17th week of 2011 patent applcation highlights part 45 |
Patent application number | Title | Published |
20110098407 | ENCAPSULATED MATERIAL COMPOSITION - An encapsulated material composition is presented, which contains a compound of Chemical Formula I and a compound of Chemical Formula II, | 2011-04-28 |
20110098408 | Deoxybenzoin-based Anti-flammable Polyphosphonate and Poly(arylate-phosphonate) Copolymer Compounds, Compositions and Related Methods of Use - Deoxybenzoin-phosphonate and other copolymer compounds, compositions and related methods. | 2011-04-28 |
20110098409 | COMPOSITIONS AND ARTICLES FOR HIGH-TEMPERATURE WEAR USE - Disclosed herein are compositions and articles that are useful in environments exposed to heat, wear, and oxidizing agents, which are improved by means of specific kinds of carbon filaments. The compositions and articles comprise high-temperature polymer, high-temperature filler, and a mixture of carbon filament, wherein said mixture of carbon filament comprises multiwall axial carbon filament. | 2011-04-28 |
20110098410 | ROOM TEMPERATURE-CURABLE COMPOSITION AND CURED PRODUCT THEREOF - The present invention provides a novel acrylic/modified silicone room temperature-curable resin composition that serves as a material for sealants having high modulus and high strength after curing, and a cured product thereof. The room temperature-curable composition includes: a (meth)acrylate ester polymer (A) having a specific silicon-containing functional group and having an alkyl (meth)acrylate ester monomer unit in its molecular chain; and a polyoxyalkylene polymer (B) having a specific silicon functional group. | 2011-04-28 |
20110098411 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF - An object of the present invention is to provide a curable composition which has excellent handling properties and which is able to form a cured product excellent in transparency, heat resistance, environment resistance and molding processability. The curable composition of the present invention comprises (a) silica fine particles, (b) a (meth)acrylate having at least two ethylenic unsaturated groups and no ring structure, (c) a (meth)acrylate having an ethylenic unsaturated group and an alicyclic structure, and (d) a polymerization initiator, said silica fine particles (a) are surface-treated with a silane compound (e) represented by the following general formula (1) and a silane compound (f) represented by the following general formula (2). | 2011-04-28 |
20110098412 | PARTIALLY HYDROGENATED POLYMER AND METHOD THEREOF - The present invention discloses a method for partially hydrogenating polymer. The method comprises providing a polymer having at least one vinyl aromatic block; and hydrogenating the polymer in presence of a heterogeneous catalyst on a support selected from the group consisting of BaSO | 2011-04-28 |
20110098413 | Acrylic star polymer - A method for obtaining a star polymer having a controlled ratio of a weight average molecular weight of the star polymer to a number average molecular weight of the star polymer, containing the steps of anionically polymerizing a (meth)acrylic ester having an alicyclic skeleton and a lactone ring in the presence of an anionic polymerization initiator to synthesize an arm polymer, reacting the arm polymer with a polyfunctional coupling agent, and reacting with an anionic polymerizable monomer. | 2011-04-28 |
20110098414 | Polymer Complex - The invention provides a polymer complex having two or more kinds of channel groups through which specific compounds ranging from gaseous small molecules to large molecules such as proteins and other biomolecules can be selectively incorporated and/or released and/or transported. The polymer complex comprises an aromatic compound having two or more coordinating sites as a ligand, a metal ion as a central metal, and an uncoordinating aromatic compound, wherein the polymer complex has a three-dimensional lattice-like structure containing a stack structure comprising the uncoordinating aromatic compound intercalated between aromatic compound ligands in a three-dimensional coordination network formed by coordinating the aromatic compound ligands to the central metal ion, the three-dimensional lattice-like structure is provided with two or more kinds of channel groups each composed of channels identical with one another and having inherent affinity for guest components, the uncoordinating aromatic compound has a specific substituent A at a specific position on the aromatic ring thereof, and the uncoordinating aromatic compound is arranged regularly such that the substituent A is directed to the inside of a specific channel group B out of the two or more kinds of channel groups. | 2011-04-28 |
20110098415 | CROSSLINKING OF REACTIVE POLYOLEFIN PREPOLYMERS USING A COREACTANT - The present invention provides a cross linked polyolefin thermoset material, comprising maleic anhydride functionalized reactive polyolefin wax cross linked with a polyamine. The thermoset may be made by a method involving reaction of a maleic anhydride functionalized reactive polyolefin wax with a polyamine. The polyolefin may be polyethylene, polypropylene and their copolymers. The polyamine is a primary or secondary alkyl polyamines, alkyl ether polyamines, aryl polyamines. Polyols may be used instead of polyamines, for example alkyl polyols, alkyl ether polyols or aryl polyols. | 2011-04-28 |
20110098416 | Method for the Continuous Thermal Secondary Surface Cross-Linking of Water-Absorbing Polymer Particles - A process for continuous thermal postcrosslinking of water-absorbing polymer particles, wherein the postcrosslinker is applied to the water-absorbing polymer particles by means of suitable nozzles and the nozzles are exchanged or cleaned via the interior of a glovebox adjoining the plant section comprising the nozzle. | 2011-04-28 |
20110098417 | POLYURETHANE POLYMER SYSTEMS - The present invention is to the preparation and application of isocyanate based polymers, particularly polyurethane and polyurea elastomeric polymers. By incorporating polybutadiene with a polyether polyol in a polyurethane system, the produced elastomer have improved chemical resistance as compared to conventional polyurethane elastomers. For polyurea elastomer, the incorporation of high functional polyols or crosslinkers with polybutadiene gives elastomer with improved chemical resistance as compared to conventional polyurea elastomers. | 2011-04-28 |
20110098418 | Additives For Detergents And Cleaning Agents - The invention relates to additives in the form of non-ionic polyesters comprising terephthalic acid, ethylene glycol, polyethylene glycol, optionally propylene glycol, C—C-alkyl-polyalkene glycol ether, and a multifunctional cross-linked monomer. Said polyesters preferably have a flow factor ff of greater than 8, and preferably have a melting point of over 40° C. and molecular weights Mp of 4,000 to 15,000 g/mol. Said polyesters are suitable as soil release components in detergents and cleaning agents. | 2011-04-28 |
20110098419 | FUNCTIONAL FILLER AND RESIN COMPOSITION CONTAINING SAME - The present invention provides a functional filler which is excellent in dispersibility or interaction with polylactic acid as a matrix polymer and can improve heat resistance, moldability and mechanical strength of the polylactic acid; and a resin composition containing the functional filler. The functional filler of the present invention is characterized in including a raw material filler and polylactic acid, wherein a surface or end the raw material filler is modified by the polylactic acid. | 2011-04-28 |
20110098420 | CURABLE POLYSILOXANE COMPOSITION, AND POLYSILOXANE CURED PRODUCT, OPTICAL MEMBER, MEMBER FOR AEROSPACE INDUSTRY, SEMICONDUCTOR LIGHT-EMITTING DEVICE, ILLUMINATING DEVICE AND IMAGE DISPLAY DEVICE USING THE SAME - The present invention provides a curable polysiloxane composition which is excellent in light resistance (particularly ultraviolet resistance) and adhesion and has a sufficient heat resistance/hydrothermal resistance and film-forming property and which generates little foaming at curing and does not generate cracks, peeling, coloring, and foaming even when used for a long period of time. A curable polysiloxane composition which comprises a specific hydrosilyl group-containing polysiloxane compound, a specific polysiloxane compound comprising two or more silanol groups in one molecule, and a dehydrogenative condensation reaction catalyst. | 2011-04-28 |
20110098421 | Process for Improving the Devolatilization of Polymer Slurry Produced in a Polymerization Reactor - The present invention relates to a process for improving the devolatilization of polymer slurry produced in an olefin polymerization reactor. The process is characterized in that it involves an adjustment of the temperature of the interior surface of the flash line for periodically transferring polymer slurry from the polymerization reactor to a downstream processing unit. In particular, in accordance with the present process, the temperature of the interior surface of the flash line is adjusted to a temperature which is equal to or higher than the softening temperature of the polymer passing through said flash line whereby said temperature is higher in a first half of the length of the flash line than in the remaining length of the flash line. | 2011-04-28 |
20110098422 | POLYETHYLENE COMPOSITIONS HAVING IMPROVED PROPERTIES - Polyethylene compositions having improved properties are provided. In one aspect, a polyethylene composition having a long chain branching index (g′ | 2011-04-28 |
20110098423 | Propylene-ethylene copolymers and process for their preparation - Random propylene/ethylene copolymers are provided characterized by
| 2011-04-28 |
20110098424 | Preparation of styrene homopolymers and styrene-ethlyene copolymers - The present invention discloses copolymers of styrene and ethylene with highly syndiotactic styrene blocks prepared with of a catalyst system comprising a metallocene catalyst component of the general formula (I): (Flu-R″—C p)M(n | 2011-04-28 |
20110098425 | Catalyst Compounds and Use Thereof - This invention relates to Group 4 catalyst compounds containing di-anionic tridentate nitrogen/oxygen based ligands. The catalyst compounds are useful, with or without activators, to polymerize olefins, particularly a-olefins, or other unsaturated monomers. Systems and processes to oligomerize and/or polymerize one or more unsaturated monomers using the catalyst compound, as well as the oligomers and/or polymers produced therefrom are also provided. | 2011-04-28 |
20110098426 | TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF THE ETHYLENE AND a-OLEFINS USING THE SAME - Provided are transition metal catalytic systems for preparing ethylene homopolymers or copolymers of ethylene with α-olefins. More specifically, provided are Group 4 transition metal catalysts, which is characterized in that the catalyst comprises around the Group 4 transition metal a cyclopentadiene derivative, and at least one aryloxide ligand(s) having a fluorenyl group or a derivative thereof (which is ready to be substituted at 9-position) that functions as an electron donor and serves to stabilize the catalytic system by surrounding an oxygen atom that links the ligand to the transition metal at ortho-position, and there is no cross-linkage between the ligands; catalytic systems comprising such transition metal catalyst and aluminoxane cocatalyst or boron compound cocatalyst; and processes for preparing ethylene homopolymers or copolymers of ethylene with α-olefins by using the same. | 2011-04-28 |
20110098427 | Catalyst Compounds And Use Thereof - Group 4 catalyst compounds containing di-anionic tridentate nitrogen/oxygen based ligands are provided. The catalyst compounds are useful, with or without activators, to polymerize olefins, particularly α-olefins, or other unsaturated monomers. Systems and processes to oligomerize and/or polymerize one or more unsaturated monomers using the catalyst compound, as well as the oligomers and/or polymers produced therefrom are also provided. | 2011-04-28 |
20110098428 | CATALYST PREPARATION USING H2 - The invention refers to a process for preparing a Group 2 metal/transition metal olefin polymerization catalyst component in particulate form having improved polymerization properties due to the use of H | 2011-04-28 |
20110098429 | Catalyst Compounds and Use Thereof - This invention relates to Group 4 catalyst compounds containing di-anionic tridentate nitrogen/oxygen based ligands. The catalyst compounds are useful, with or without activators, to polymerize olefins, particularly a-olefins, or other unsaturated monomers. Systems and processes to oligomerize and/or polymerize one or more unsaturated monomers using the catalyst compound, as well as the oligomers and/or polymers produced therefrom are also provided. | 2011-04-28 |
20110098430 | Catalyst Compounds and Use Thereof - This invention relates to Group 4 catalyst compounds containing di-anionic tridentate nitrogen/oxygen based ligands. The catalyst compounds are useful, with or without activators, to polymerize olefins, particularly α-olefins, or other unsaturated monomers. Systems and processes to oligomerize and/or polymerize one or more unsaturated monomers using the catalyst compound, as well as the oligomers and/or polymers produced therefrom are also provided. | 2011-04-28 |
20110098431 | Catalyst Compounds and Use Thereof - This invention relates to Group 4 dialkyl compounds supported by a pyridyl-amido-aryl (“PAA”), an anisole-amido-aryl (“AAA”), a phenoxy-amido-pyridyl (“PAPY”), an anisole-amido-phenoxy (“AAP”) or a anisole-amido-phenoxy (“AAP”) tridentate ligand. Such compounds can polymerize olefins, such as ethylene. | 2011-04-28 |
20110098432 | Coordination Complex - The present invention provides a complex of formula I | 2011-04-28 |
20110098433 | RESIST COPOLYMERS CONTAINING PHOTOACID GENERATORS FOR LITHOGRAPHIC APPLICATIONS AND ITS METHOD OF PREPARATION - Disclosed is a copolymer suitable for use as a resist for atomic force microscope (AFM) lithography or e-beam lithography. The copolymer contains fluoroalkylsulfonium salts as photoacid generators. The copolymer has high solubility in organic solvents and high coating ability. In addition, the copolymer can be patterned with high sensitivity and resolution by lithography. Further disclosed is a method of preparation for the copolymer. | 2011-04-28 |
20110098434 | ISOPRENE-BASED POLYMER CYCLIZED PRODUCT, ALICYCLIC POLYMER, AND OPTICAL RESIN - An isoprene-based polymer cyclized product obtained by cyclization of an isoprene-based polymer containing structural units expressed by the general formula (1) and having a ratio of content of the structural units to all repeating structural units of 60 mol % or more; an alicyclic polymer obtained by hydrogenation of 50% or more of the carbon-carbon double bonds of the isoprene-based polymer; and an optical resin comprising the isoprene-based polymer cyclized product and alicyclic polymer. | 2011-04-28 |
20110098435 | RU SULFOXIDE COMPLEXES, THEIR PREPARATION AND USE - Ru(0) complexes containing sulfoxide ligands and aliphatically unsaturated ligands are effective hydrosilylation catalysts useful in particular for addition curing organosilicon compositions. | 2011-04-28 |
20110098436 | IPA/Polyester copolymer fiber - A process for producing an IPA/PET copolymer fiber that is homogenous having a substantially level, single IPA copolymer content, said fiber having improved pilling resistance and dye uptake. | 2011-04-28 |
20110098437 | Copolymer and Method for Manufacturing the Same and Packaging Material Utilizing the Same - The disclosed is a copolymer having a formula as: | 2011-04-28 |
20110098438 | Production Process of Alpha-Hydroxy Acids - An object of the present invention is to provide a production process of an α-hydroxy acid having a sufficient quality as a polymer raw material, which process does not produce a large amount of waste as a byproduct and is economical. | 2011-04-28 |
20110098439 | INSULINS WITH AN ACYL MOIETY COMPRISING REPEATING UNITS OF ALKYLENE GLYCOL CONTAINING AMINO ACIDS - Acylated insulins wherein an acyl moiety is attached to the parent insulin and wherein said acyl moiety comprises repeating units of alkylene glycol containing amino acids and wherein there is only one lysine residue (K & Lys) in the parent insulin have satisfactory properties when administered pulmonary. | 2011-04-28 |
20110098440 | Insulin Analogues with an Acyl and Alkylene Glycol Moiety - An acylated insulin analogue wherein the insulin analogue comprises a lysine residue connected C-terminally to the A21 amino acid residue or a peptide residue of up to 4 amino acid residues comprising a lysine residue which peptide residue is connected C-terminally to the A21 amino acid residue, characterized in that an acyl moiety comprising an alkylene glycol moiety is attached to the lysine residue in the A22 position or attached to a lysine residue present in the peptide residue that is attached to the C terminal end of the A21 amino acid residue and wherein there is only one lysine (K, Lys) in the insulin analogue, can conveniently be administered pulmonary. | 2011-04-28 |
20110098441 | Label target and labeling reagents comprising backbones with at least two consecutive peptide bonds - This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes. These labeling reagents are useful for labeling probes or targets, including nucleic acids and proteins. These reagents can be usefully applied to protein and nucleic acid probe based assays. They are also applicable to real-time detection processes. | 2011-04-28 |
20110098442 | PEPTIDES AND PEPTIDE DERIVATIVES AS WELL AS PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - Peptides and peptide derivatives of the following general Formula (I): H | 2011-04-28 |
20110098443 | Anti-GLP-1R Antibodies and Their Uses - The present invention relates to antibodies reactive with GLP-1R, and methods of making and using them. | 2011-04-28 |
20110098444 | METHODS OF PREPARATION AND COMPOSITION OF PEPTIDE CONSTRUCTS USEFUL FOR TREATMENT OF RHEUMATOID ARTHRITIS - The invention is related to peptide constructs, i.e., polypeptides obtained by linking together two or more peptides based on or derived from different molecules, which are useful in the treatment or prevention of autoimmune diseases, specifically rheumatoid arthritis (RA) and compositions containing same, methods for producing same and methods for using same; wherein the peptide constructs have the formula P | 2011-04-28 |
20110098445 | COVALENT ATTACHMENT OF PEPTIDES AND BIOLOGICAL MOLECULES TO LUMINESCENT SEMICONDUCTOR NANOCRYSTALS - A method for covalent attachment of peptides to luminescent quantum dots or other inorganic nanoparticles. The first step in the method involves functionalizing at least a portion of a surface of the quantum dot or nanoparticle with one or more materials having at least one reactive functional group therein. Subsequently, a peptide having a reactive functional group is reacted with at least some of the quantum dot or nanoparticle reactive functional groups to covalently bond at least some of the peptide to the quantum dots or nanoparticles. Modifications of the basic method are disclosed which provide methods allowing customized fabrication of quantum dots having a variety of different functional properties and combinations of functional properties. Also disclosed are quantum dots and nanoparticles made by the methods of the present invention. | 2011-04-28 |
20110098446 | Use of a tetraphenylborate (TPB) salt for the separation of biomolecules - Process for the separation of a biomolecule containing at least one cationic group from a liquid medium containing said biomolecule, which comprises the use of a tetraphenylborate (TPB) salt. | 2011-04-28 |
20110098447 | Homogenous Populations of Molecules - The invention provides populations of molecules that are prepared as, or treated to become, homogeneous for one or more molecular characteristics. In an aspect, the invention relates to molecular weight standards that may be used to determine the molecular weight or apparent molecular weight of uncharacterized molecules, such as proteins and nucleic acids, as well as in other applications. In one aspect, the molecular weight standards are pre-stained. | 2011-04-28 |
20110098448 | ANTI-PRION PROTEIN ANTIBODY FRAGMENT - The invention relates to an antibody, antibody fragment or derivative thereof which specifically recognizes a prion protein and which comprises a complementarity determining region (CDR), a retro-inverso D-peptide of said CDR and/or an anti-idiotypic antibody, antibody fragment or derivative thereof which recognizes said CDR. The invention further concerns a nucleic acid molecule encoding said antibody, antibody fragment or derivative thereof as well as a method for generating an antibody, antibody fragment or derivative thereof that specifically recognizes a prion protein, wherein an antibody that recognizes a specific domain of the prion protein is generated, an antigen-specific amino acid sequence is isolated from said antibody, and an anti-idiotypic antibody, antibody fragment or derivative thereof, which recognizes said antigen-specific amino acid sequence, is generated. | 2011-04-28 |
20110098449 | MODULATORS OF HEPATOCYTE GROWTH FACTOR ACTIVATOR - The invention provides methods and compositions for modulating hepatocyte growth factor activator function. | 2011-04-28 |
20110098450 | Antibody Molecules - The present invention provides pharmaceutical compositions comprising second-generation molecules that are superior than TOCILIZUMAB, by altering the amino acid sequences of the variable and constant regions of TOCILIZUMAB, which is a humanized anti-IL-6 receptor IgG1 antibody, to enhance the antigen-neutralizing ability and increase the pharmacokinetics, so that the therapeutic effect is exerted with a less frequency of administration, and the immunogenicity, safety and physicochemical properties (stability and homogeneity) are improved. The present invention also provides methods for producing these pharmaceutical compositions. The present inventors have successfully generated second-generation molecules that are superior to TOCILIZUMAB by appropriately combining amino acid sequence alterations in the CDR domains, variable regions, and constant regions. | 2011-04-28 |
20110098451 | PEPTIDE-POLYMER CONJUGATES - This invention relates to a conjugate of a polymer moiety and an erythropoietin moiety. | 2011-04-28 |
20110098452 | PURIFICATION OF MODIFIED CYTOKINES - The invention provides an efficient method of purification of a modified cytokine. The process includes the use of a chromatographic technique for the purification of the desired cytokine. The purified cytokine can be used as a therapeutic composition. | 2011-04-28 |
20110098453 | MAGNETIC NANOCOMPOSITE, AND PROCESS FOR SELECTIVE BINDING, SEPARATION AND PURIFICATION OF PROTEIN USING THE SAME - The present invention relates to a magnetic nanocomposite, a process for production thereof, a reusable protein-binding agent for separation of a protein including the magnetic nanocomposite, and a process for selective binding, separation and purification of a protein using the magnetic nanocomposite. In particular, the present invention is directed to a magnetic nanocomposite with a magnetic nanoparticle core of a magnetic nanoparticle, a silica shell coating said core, and a nanoparticle layer of a fourth period transition metal oxide, which coats said silica shell, a process for production of the magnetic nanocomposite, a reusable protein-binding agent the magnetic nanocomposite, and a process for selective binding, separation and purification of a protein using the magnetic nanocomposite. | 2011-04-28 |
20110098454 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND - Provided is an easy method for production of a high-performance polyfunctional compound which can be used as an optical recording material, an optical waveguide material, a photo-alignment film material, or the like, in a simple manner. The method for production of a polyfunctional compound includes conducting a Michael addition of a compound (A) having a hydrogen atom of pKa≦15 to a (meth)acrylate or a (meth)acrylamide (B), in which at least one of the compounds (A) and (B) has a photoisomerization group and/or a liquid-crystalline group. | 2011-04-28 |
20110098455 | Crosslinked polysaccharide sponge - A process for producing a polysaccharide sponge comprises the steps of (A) freezing a photoreactive polysaccharide solution, and (B) irradiating the frozen photoreactive polysaccharide solution with light to crosslink the photoreactive polysaccharide, thereby obtaining the polysaccharide sponge. The process includes simplified steps requiring no removal of solvent, and has such an advantage that impurities are easily removed therefrom. | 2011-04-28 |
20110098456 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES - The invention relates to oligonucleotides including at least one FANA substituted nucleotide analog and a pyrimidine-purine dinucleotide. The invention also relates to pharmaceutical compositions and methods of use thereof. | 2011-04-28 |
20110098457 | METHODS OF ATTACHING BIOLOGICAL COMPOUNDS TO SOLID SUPPORTS USING TRIAZINE - Disclosed are methods of attaching biologically active compounds to a solid surface, comprising modifying the solid surface using triazine chloride and attaching the biologically active compound to the triazine moiety. | 2011-04-28 |
20110098458 | Isolated Nucleic Acid Molecules From Transgenic Papaya Line 16-0-1 Resistant To Papaya Ringspot Virus And Use Thereof - Provided is an isolated nucleic acid molecule having a right border flanking region, a left border flanking region and a transgene sequence between the right border flanking region and the left border flanking region, wherein the right border flanking region having at least 90% homology with the sequence set forth in SEQ ID NO: 29; the left border flanking region having at least 90% homology with the sequence set forth in SEQ ID NO: 31; and the transgene sequence having a papaya ringspot virus coat protein gene and a promoter operably linked to the papaya ringspot virus coat protein gene. Primers, probes and kit derived from the isolated nucleic acid molecule are proved to be useful for identifying the transgenic papaya line 16-0-1 in a specific, reproducible, sensitive and reliable way. | 2011-04-28 |
20110098459 | Isolated Nucleic Acid Molecules From Transgenic Papaya Line 18-2-4 Resistant To Papaya Ringspot Virus And Use Thereof - Provided is an isolated nucleic acid molecule having a right border flanking region, a left border flanking region and a transgene sequence between the right border flanking region and the left border flanking region, wherein the right border flanking region having at least 90% homology with the sequence set forth in SEQ ID NO: 30; the left border flanking region having at least 90% homology with the sequence set forth in SEQ ID NO: 32; and the transgene sequence having a | 2011-04-28 |
20110098460 | SiRNA Useful to Suppress expression of eIF-5A1 - The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis factor 5A1 or simply factor 5A1, apoptosis factor 5A1 nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of factor 5A1. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines by inhibiting expression of apoptosis factor 5A. | 2011-04-28 |
20110098461 | Novel RNA Interference Methods Using DNA-RNA Duplex Constructs - The present invention provides novel compositions and methods for suppressing the function or activity of a targeted gene through a novel intracellular piRNA-mediated RNAi mechanism, using RNA-DNA duplex constructs. The invention further provides novel methods and compositions for generating or producing RNA-DNA duplex agents, whose quantity is high enough to be used for the invention's gene silencing transfection and possibly in therapeutics applications. This improved RNA-polymerase chain reaction (RNA-PCR) method utilizes thermocycling steps of promoter-linked DNA or RNA template synthesis, in vitro transcription and then reverse transcription to bring up the amount of RNA-DNA duplexes up to two thousand folds within one round of the above procedure for using in D-RNAi-directed gene silencing. | 2011-04-28 |
20110098462 | METHOD AND KIT FOR THE SAMPLE PRESERVATION AND CELL DISRUPTION BEFORE THE EXTRACTION OF NUCLEIC ACIDS - The invention relates to a method for preserving samples and disrupting cells which can be employed for the preparation of the extraction of nucleic acids from live cells, cell aggregates and tissue samples, and to a kit for carrying out the method. The method includes the introduction of live cells, cell aggregates or tissue samples whose nucleic acids are to be extracted into an excess of water-miscible and volatile organic liquid. The saturation of the sample with the organic liquid has an advantageous effect on the extraction of the nucleic acids, which is subsequently carried out in an aqueous medium. The mechanical cell disruption is facilitated by the virtually complete removal of the water from the cells. The biomembranes are dissolved in the organic liquid. tRNA and other RNA fractions with a low degree of polymerization, which are capable of permeating across the cell wall, can be extracted selectively without mechanical disruption. Before high-molecular-weight nucleic acids are extracted, the cells, cell aggregates or tissue samples are disrupted in the organic liquid with the aid of mechanical pulses. Since the nucleases are inactive in the dehydrated organic liquid, the biological samples or the homogenates prepared therefrom can be stored at room temperature in the organic liquid as long as desired. After incubation in the largely anhydrous organic liquid, the sample's nucleases are largely denatured. An advantageous kit according to the invention contains a mixed organic/aqueous phase with denaturing properties and, for each sample, a shaped body for dehydration which is adapted to suit the size of the preservation container, and a mixture, adapted to suit the size of the preservation container, of a few large and many small disruption bodies for the disruption in the nonaqueous medium. A considerable advantage of the invention is the fact that cooling and powerful mechanical pulses when disrupting the cells and during the extraction may be dispensed with, and that DNA extraction and cell disruption can be carried out at different times. | 2011-04-28 |
20110098463 | CELLULOSE DERIVATIVE AND METHOD FOR PRODUCING THE SAME, CELLULOSE RESIN COMPOSITION, MOLDED MATTER AND METHOD FOR MAKING THE SAME, AND ELECTRICAL AND ELECTRONIC EQUIPMENT HOUSING - A cellulose derivative obtained from cellulose by substitution of hydrocarbyl groups ranging in carbon number from 1 to 7 and aliphatic acyl groups ranging in carbon number from 4 to 11 for at least part of the hydrogen atoms of hydroxyl groups contained in the cellulose. The cellulose derivative can exhibit good thermal plasticity, strength, heat resistance and mold working suitability. | 2011-04-28 |
20110098464 | CELLULOSE INTERPOLYMERS AND METHODS OF OXIDATION - This invention provides cellulose ester interpolymers, and methods of oxidizing cellulose interpolymers and cellulose ester interpolymers. The invention also provides routes to access carboxylated cellulose ester derivatives with high acid numbers wherein the carboxyl group is attached directly to the cellulose backbone by a carbon-carbon bond. Through functionalization of an intermediate aldehyde, the corresponding cationic or zwitterionic cellulose ester derivatives can also be accessed. The interpolymers of the present invention have a number of end-use applications, for example, as binder resins in various types of coating compositions and as drug delivery agents. | 2011-04-28 |
20110098465 | Nonflow -Through Apparatus And Method Using Enhanced Flow Mechanisms - Methods and apparatus for facilitating the synthesis of compounds in a nonflow-through device are presented. Application of the nonflow-through methods and microfluidic devices to the synthesis of radiolabeled compounds is described. These methods and apparatus enable the introduction of a pressurized gas through a tangential slit into a vortex reactor of the nonflow-through device, while one or more liquids are delivered to the reaction chamber through the same or different inlet ports. The introduction of the pressurized gas produces a cyclonic motion of the mixture within the reactor. Such a mechanism may be used to facilitate the evaporation of various liquids within the reactor at lower temperatures, thus reducing the production of unwanted byproducts that are associated with the use of high temperatures. In addition, thorough mixing of various liquids may be effected rapidly while allowing chemical reactions to take place efficiently within the vortex reactor. | 2011-04-28 |
20110098466 | Synthesis Of Triphenodioxazine Pigments - The invention relates to a process for the preparation of compounds of the general formula (I) where X are halogen atoms, the rings labeled A are linearly or angularly fused in position 1,2; 2,3 or 3,4, and in position 8,9; 9,10 or 10,11, to a 5- or 6-membered heterocyclic ring containing in the ring one nitrogen atom and one oxygen atom, or containing in the ring two nitrogen atoms, comprising an oxidation of a 3,6-bisarylamino-2,5-dihalobenzoquinone of the formula (II) in an aprotic-polar organic solvent in the presence of an organic sulfonic acid. | 2011-04-28 |
20110098467 | PYRROLO-TRIAZINE ANILINE COMPOUNDS USEFUL AS KINASE INHIBITORS - Compounds having the formula (I), | 2011-04-28 |
20110098468 | NK1 ANTAGONISTS | 2011-04-28 |
20110098469 | 1-THIO-D-GLUCITOL DERIVATIVES - The present invention provides a 1-thio-D-glucitol compound of the following formula, which shows the action of inhibiting the activity of SGLT2, a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the salt; and a pharmaceutical comprising such a compound as an active ingredient, especially, a pharmaceutical for preventing or treating diabetes, diabetes-related disease, or diabetic complication. The invention also provides a method for producing the 1-thio-D-glucitol compound and its intermediate. | 2011-04-28 |
20110098470 | METHOD FOR PRODUCING THE TRISODIUM SALT OF 2,4,6-TRIMERCAPTO-S-TRIAZINE - The invention relates to a method for producing the trisodium salt of 2,4,6-trimercapto-s-triazine, cyanuric chloride being reacted in an aqueous medium at a temperature of 20 to 70° C. using NaSH, Na | 2011-04-28 |
20110098471 | OXAZOLIDINONE DERIVATIVE HAVING FUSED RING - The present invention provides a novel antimicrobial drug comprising an oxazolidinone derivative of the formula (I): | 2011-04-28 |
20110098472 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES - The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof. | 2011-04-28 |
20110098473 | NOVEL TRANSITION METAL COMPLEXES AND USE THEREOF IN ORGANIC LIGHT EMITTING DIODES - III - Metal complexes comprising at least one polycyclic aromatic ligand which is bonded to the central metal via two nitrogen atoms, an organic light-emitting diode comprising at least one inventive metal complex, a light-emitting layer comprising at least one inventive metal complex, an organic light-emitting diode comprising at least one inventive light-emitting layer, the use of the at least one inventive metal complex in organic light-emitting diodes, and a device selected from the group consisting of stationary visual display units such as visual display units of computers, televisions, visual display units in printers, kitchen appliances and advertising panels, illuminations, information panels and mobile visual display units such as visual display units in cellphones, laptops, digital cameras, vehicles, and destination displays on buses and trains, comprising at least one inventive organic light-emitting diode. | 2011-04-28 |
20110098474 | PROCESS FOR THE SYNTHESIS OF MORPHINANE COMPOUNDS AND INTERMEDIATES THEREOF - This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds. | 2011-04-28 |
20110098475 | FLUORESCENT PROBES - A fluorescent probe which is represented by the following formula (wherein R | 2011-04-28 |
20110098476 | PROCESS FOR PREPARING BIS(THIOHYDRAZIDE AMIDES) - Disclosed herein are methods of preparing a bis(thio-hydrazide amides) compounds of the following structural formula: wherein R | 2011-04-28 |
20110098477 | Method Of Producing Compound Having Anti-Hcv Activity - There is provided a convenient and inexpensive method of producing a compound which has a high activity of inhibiting replication of hepatitis C virus (HCV) and is useful for preventing and treating a liver disease caused by HCV infection. | 2011-04-28 |
20110098478 | FUSED THIOPHENES AND METHODS FOR MAKING AND USING SAME - Disclosed are compounds having one of the following formulae (11), (12), wherein X is an aromatic nucleophilic substitution leaving group; R | 2011-04-28 |
20110098479 | CONDENSATION REACTION BY METAL CATALYST - The invention relates to a method for producing an azoline compound represented by the general formula (3): | 2011-04-28 |
20110098480 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR - A compound represented by the formula (I) or a pharmacologically acceptable salt thereof is used as an activator of PPAR. | 2011-04-28 |
20110098481 | NOVEL EP4 AGONIST - Provided is a compound represented by the formula (1): | 2011-04-28 |
20110098482 | METHODS OF PREPARING 1-(4-((1R,2S,3R)-1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL)ETHANONE - Methods of preparing 1-(4-((1R,2S,3R)-1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone and derivatives thereof are disclosed. | 2011-04-28 |
20110098483 | Substituted Nitrogen Heterocycles and Synthesis and Uses Thereof - The invention relates to a nitrogen heterocycle compound of formula 1: | 2011-04-28 |
20110098484 | PROCESS FOR PRODUCTION OF 1-(3-(2-(1-BENZOTHIOPHEN-5-YL)- ETHOXY)PROPYL)AZETIDIN-3-OL OR SALTS THEREOF - A Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which comprises using as a starting compound as a (phenylthio)acetic acid derivative or salts thereof represented by the general formula: | 2011-04-28 |
20110098485 | BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS - Compounds of the formula I, in the form of mixtures comprising predominantly one enantiomer or in the form of pure enantiomers, secondary phosphine-Q-P*(═O)HR | 2011-04-28 |
20110098486 | Aromatic enediyne derivative, organic semiconductor thin film, electronic device and methods of manufacturing the same - Disclosed are a novel aromatic enediyne derivative, an organic semiconductor thin film using the same, and an electronic device. Example embodiments pertain to an aromatic enediyne derivative which enables the formation of a chemically and electrically stable and reliable semiconductor thin film using a solution process, e.g., spin coating and/or spin casting, at about room temperature when applied to devices, an organic semiconductor thin film using the same, and an electronic device including the organic semiconductor thin film. A thin film having a relatively large area may be formed through a solution process, therefore simplifying the manufacturing process and decreasing the manufacturing cost. Moreover, it is possible to provide an organic semiconductor that may be effectively applied to various fields including organic thin film transistors, electroluminescent devices, solar cells, and memory. | 2011-04-28 |
20110098487 | NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS - There are described novel rhodamine color-forming compounds. The rhodamine color-forming compounds exhibit a first color when in a crystalline form and a second color, different from the first color, when in an amorphous form. Thermal imaging members containing these color-formers are also described. | 2011-04-28 |
20110098488 | Process for Oxidizing Organic Substrates By Means of Singlet Oxygen Using a Modified Molybdate LDH Catalyst - Oxidation of organic substrates by means of singlet oxygen, in which organic substrates which react with | 2011-04-28 |
20110098489 | PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND - A method of producing a corresponding acetal compound which comprises reacting a benzal halide compound represented by formula (1) | 2011-04-28 |
20110098490 | PROCESS FOR PREPARATION OF FORMATE SALT - Processes for the recovery of formate salt from biomass and the product obtained thereof generally include subjecting an aqueous liquid mixture containing levulinic acid, formic acid and possibly furfural to a liquid-liquid extraction process, followed by the recovery of the furfural, the formate salt and the levulinic acid or the levulinate salt. | 2011-04-28 |
20110098491 | Direct epoxidation process using alkanoic acid modifier - The invention is a process for epoxidizing an olefin with hydrogen and oxygen in the presence of an alkanoic acid and a catalyst comprising a noble metal and a titanium zeolite, wherein the catalyst has not been reduced prior to epoxidation. This process surprisingly gives significantly improved productivity and reduced formation of unwanted propane compared to processes that do not use the alkanoic acid modifier. | 2011-04-28 |
20110098492 | CLEANING COMPOSITIONS CONTAINING MID-RANGE ALKOXYLATES - Cleaning compositions are described comprising mid-range alkoxylate surfactants or blends of alkoxylate surfactants, and their use as cleaners for triglycerides and cross-linked triglycerides, formula stabilization agents, agents for ultra-concentrated cleaning formulations, pre-wash spotters, detergents, agricultural adjuvants, hard surface cleaning, and emulsifiers. | 2011-04-28 |
20110098493 | Method of separating ergosterol - The present invention provides a method of separating ergosterol from a solution containing ergosterol in water-insoluble organic solvent, comprising supplying water to the solution and precipitating ergosterol. According to the method of the present invention, ergosterol crystals can be obtained at a high yield. Moreover, controlled water supply provides granular ergosterol aggregates exhibiting good solid-liquid separation character at a high yield. | 2011-04-28 |
20110098494 | METHOD OF HYDROTREATING FEEDS FROM RENEWABLE SOURCES WITH INDIRECT HEATING USING A CATALYST BASED ON NICKEL AND MOLYBDENUM HAVING A PARTICULAR ATOMIC RATIO - The invention describes a method of treating feeds from renewable sources comprising a hydrotreatment stage comprising at least two catalytic zones in which the entry stream comprising said feed mixed with at least a part of a hydrotreated liquid effluent from stage b) is introduced into the first catalytic zone at a temperature comprised between 150 and 260° C., and the effluent from the first catalytic zone is then introduced, mixed with at least a part of a hydrotreated liquid effluent from stage b) and preheated, into the following catalytic zone or zones at a temperature comprised between 260 and 320° C., and a stage of separation of the effluent from the hydrotreatment stage permitting the separation of a gaseous effluent and a hydrotreated liquid effluent of which at least a part is recycled at the top of each catalytic zone, said method using, in at least the catalytic zone or zones following the first, a bulk or supported catalyst comprising an active phase constituted by at least one group VIB element and at least one group VIII element, said elements being in sulphide form and the atomic ratio of the group VIII metal to the group VIB metal being strictly greater than 0 and less than 0.095. | 2011-04-28 |
20110098495 | Compositions and methods of omega polyunsaturated fatty acids for the treatment of oral diseases - The invention discloses a novel discovery of anti-microbial activity against oral bacteria, which can be applied for controlling and preventing oral diseases, of omega-3, omega-6, and omega-9 fatty acids, but not limited to omega-3, omega-6, and omega-9 fatty acids; omega-3, omega-6, and omega-9 fatty acid methyl esters, and omega-3, omega-6, omega-9 fatty acid ethyl esters and their application method. The application of this discovery includes the preparation of drugs, dietary supplements, food and daily necessities with oral health care and therapeutic effects. | 2011-04-28 |
20110098496 | NOVEL COMPLEXES AND METHOD FOR SYNTHESIS OF GROUP 6 ORGANOMETALLICS, AND USE THEREOF IN AN OLEFIN METATHESIS METHOD - Novel group 6 organometallic compounds are obtained by reaction of at least one boron compound comprising at least one hydroxy, sulfhydryl or amino function with at least one compound of a group 6 transition metal. These compounds are used in a catalytic composition utilized in an olefin metathesis method. | 2011-04-28 |
20110098497 | NOVEL COMPLEXES AND METHOD FOR SYNTHESIS OF GROUP 6 ORGANOMETALLICS GRAFTED ON ANIONS, AND USE THEREOF IN AN OLEFIN METATHESIS METHOD - Novel group 6 organometallic compounds, supported on anions by means of at least one covalent metal-oxygen bond, are obtained by reaction of at least one borate or aluminate comprising at least one hydroxy group with at least one compound of a group 6 transition metal. These compounds are used in a catalytic composition utilized in an olefin metathesis method. | 2011-04-28 |
20110098498 | Processes For Preparing A Polymeric Compound - The present invention provides methods for preparing a polymeric compound of Formula I: | 2011-04-28 |
20110098499 | PROCESS FOR CONTINUOUS PRODUCTION OF ORGANIC CARBONATES OR ORGANIC CARBAMATES AND SOLID CATALYSTS THEREFORE - Processes for the alcoholysis, inclusive of transesterification and/or disproportionation, of reactants are disclosed. The alcoholysis process may include feeding reactants and a trace amount of soluble organometallic compound to a reactor comprising a solid alcoholysis catalyst, wherein the soluble organometallic compound and the solid alcoholysis catalyst each independently comprise a Group II to Group VI element, which may be the same element in various embodiments. As an example, diphenyl carbonate may be continuously produced by performing transesterification over a solid catalyst followed by disproportionation, where a trace amount of soluble organometallic compound is fed to the transesterification reactor. Also disclosed is a process for reactivating a spent solid alcoholysis catalyst, such as a catalyst useful for transesterifications and/or disproportionations, the process including removing polymeric materials deposited on the catalyst and re-depositing catalytically active metals on the solid catalyst. | 2011-04-28 |
20110098500 | Polymerizable Fluorine-Containing Compound - A polymerizable fluorine-containing compound represented by formula (1), | 2011-04-28 |
20110098501 | PROCESSES FOR MAKING ETHANOL OR ETHYL ACETATE FROM ACETIC ACID USING BIMETALLIC CATALYSTS - A process for selective formation of ethanol and/or ethyl acetate from acetic acid by hydrogenating acetic acid in the presence of a Pt/Sn catalyst or a Re/Pd catalyst. The catalyst may further comprise a support modifier to improve selectivity for the desired product. | 2011-04-28 |
20110098502 | NEW PROCESS FOR RESOLVING S-3- (AMINOMETHYL)-5-METHYLHEXANOIC ACID - The present invention relates to a process for resolving S-3-(Aminomethyl)-5-methylhexanoic acid, which adopts benzoyl-L-glutamic acid, 4-methyl benzoyl-L-glutamic acid, benzene sulfonyl-L-glutamic acid or 4-methyl benzene sulfonyl-L-glutamic acid as a resolution agent to make a first resolution to racemic 3-aminomethyl-5-methylhexanoic acid, and adopts the resolution agent same to that of the first resolution to make a second resolution to the first resolution product to obtain the second resolution product, thus the resolution salt product is obtained, and further hydrolyzed by an acid, the resolution agent is extracted to be separated, the pH is adjusted to be neutral, the product S-3-(Aminomethyl)-5-methylhexanoic acid, i.e. the pregabalin, is then precipitated by distillation, therefore the present invention has the characteristics of polluting the environment slightly, high efficiency and stability, simpleness and practicality, producing product with high purity and a low sproduction cost, and is suitable for large-scale production. | 2011-04-28 |
20110098503 | ENERGY DENSIFICATION OF BIOMASS-DERIVED ORGANIC ACIDS - A process for upgrading an organic acid includes neutralizing the organic acid to form a salt and thermally decomposing the resulting salt to form an energy densified product. In certain embodiments, the organic acid is levulinic acid. The process may further include upgrading the energy densified product by conversion to alcohol and subsequent dehydration. | 2011-04-28 |
20110098504 | Histone Deacetylase Inhibitors and Methods of Use Thereof - The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention. | 2011-04-28 |
20110098505 | Process for Enantioselective Synthesis of Single Enantiomers of Thio-Substituted Arylmethanesulfinyl Derivatives by Asymmetric Oxidation - The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of:
| 2011-04-28 |
20110098506 | METHOD OF PREPARING O-DESMETHYLVENLAFAXINE - A method of preparing O-desmethylvenlafaxine from Venlafaxine or its pharmaceutically acceptable salt is disclosed. The disclosed method involves the use of mercapto carboxylic acids in the presence of suitable solvents under alkaline conditions. The disclosed process provides a novel and industrially feasible process for the preparation of O-desmethylvenlafaxine. The disclosed process also provides a cost effective, non-hazardous and efficient process for preparing O-desmethylvenlafaxine. | 2011-04-28 |