16th week of 2016 patent applcation highlights part 20 |
Patent application number | Title | Published |
20160107925 | METHODS FOR FORMING VIAS IN GLASS SUBSTRATES - Methods for forming vias in glass substrates by laser drilling and acid etching are disclosed. In one embodiment, a method forming a via in a glass substrate includes laser drilling the via through at least a portion of a thickness of the glass substrate from an incident surface of the glass substrate. The method further includes etching the glass substrate for an etching duration to increase a diameter of an incident opening of the via and applying ultrasonic energy to the glass substrate during at least a portion of the etching duration. The applied ultrasonic energy has a frequency between 40 kHz and 192 kHz. | 2016-04-21 |
20160107926 | MANUFACTURING METHOD OF FLEXIBLE SUBSTRATE - A manufacturing method of a flexible substrate is provided. The method comprises: coating a flexible substrate material and drying it; using a mask to expose the dried flexible substrate material, wherein the mask has a plurality of opaque regions distanced from each other, and the opaque regions form a designed pattern; developing the flexible substrate material to remove a portion of the flexible substrate material except the opaque regions; and curing the flexible substrate material to form a plurality of films comprising the flexible substrate material, which correspond to the designed pattern. | 2016-04-21 |
20160107927 | DECORATIVE GLASS AND METHOD FOR MANUFACTURING THE SAME - The present invention relates to a method for manufacturing decorative glass which comprises the steps of: preparing a glass; coating a water-based pigment on one surface of the prepared glass; covering the glass in which the water-based pigment has been coated with a vinyl or a wrap, forming a pattern on the vinyl or wrap covering the glass; removing the vinyl or wrap in which the pattern has been formed; and drying the glass in which the vinyl or wrap has been removed. | 2016-04-21 |
20160107928 | GLASS-FILM LAMINATES WITH CONTROLLED FAILURE STRENGTH - A glass-film laminate or article having a narrow failure distribution or a Weibull modulus of greater than 10. In embodiments, the glass-film laminate or article includes at least one first film disposed on a strengthened glass substrate. A first film or any additional films can exhibit an average strain-to-failure that is less than the strain-to-failure of the strengthened glass substrate. In embodiments, the first film is adhered to the glass substrate such that the first film does not exhibit visible delamination from the glass substrate. Methods of forming glass-film laminates or articles with a desired strength level and narrow failure strength distribution are also disclosed. | 2016-04-21 |
20160107929 | COATING COMPOSITIONS FOR ROOFING GRANULES, DARK COLORED ROOFING GRANULES WITH INCREASED SOLAR HEAT REFLECTANCE, SOLAR HEAT-REFLECTIVE SHINGLES AND PROCESS FOR PRODUCING THE SAME - Dark colored roofing granules include an inert base particle coated with a composition including a metal silicate, a non-clay latent heat reactant, and a dark colored but solar reflective pigment. | 2016-04-21 |
20160107930 | METHOD FOR PROCESSING STEEL SLAG AND HYDRAULIC MINERAL BINDER - The invention relates to a method for processing steel slag to produce a hydraulic mineral binder with a high hardening potential and to recover iron. There is provision for this purpose to provide a feed product comprising steel slag with MnO. This feed product is further processed as a melt by introducing reducing agents into the melt. A lime saturation factor of between 90 and 110 is hereby to be achieved in the mineral melt portion. Subsequently the melt is cooled in a defined manner and elemental iron is mechanically separated from the solidified melt. The solidified melt is then supplied for use as hydraulic mineral binder. | 2016-04-21 |
20160107931 | COMPOSITIONS WITH SYNTHETIC GYPSUM AND METHODS - DTPA-coated synthetic calcined gypsum is provided with alpha-like properties and obtained by spray-coating the synthetic caclined gypsum with DTPA. Cementitious compositions comprising DTPA-coated synthetic calcined gypsum and low water demand are provided as well. Methods for controlling an open time of a cementitious slurry by increasing or decreasing the amount of DTPA-coated synthetic calcined gypsum in the slurry are provided as well. | 2016-04-21 |
20160107932 | Process for the Preparation of Cement, Mortars, Concrete Compositions Containing a Calcium Carbonate - Based Filler Treated with an Ultrafine Filler and a Superplasticizer, Compositions and Cement Products Obtained and Their Applications - PROCESS for the preparation of cement/mortar/concrete compositions or systems, (for simplicity hereafter “cement” compositions or systems or even “cements”), of a generally known type containing low or medium (standard) “filler(s)”, and/or optionally HP filler(s), as carbonate-based filler(s), namely coarse low or medium calcium carbonate(s), namely coarse marble(s); Product comprising, or consisting of, the pre-blend (A) of coarse, low or medium (or optionally HP) “calcium carbonate-based filler” pre-blended with at least an UF; Aqueous compositions (B) obtained by mixing the above pre-blend (A) of coarse filler(s) with UF(s) with an aqueous system such as mix water, aqueous mix fluid; Product (C) consisting of, or comprising, the pre-blend (A) or the compositions (B), treated or pretreated with at least one superplastifier or aqueous system containing superplastifier(s); Cement and Use of cement. | 2016-04-21 |
20160107933 | BELITE-CALCIUM ALUMINATE AS AN ADDITIVE - The present invention relates to the use of a belite calcium aluminate obtainable in a method comprising the following steps:
| 2016-04-21 |
20160107934 | INORGANIC ADMIXTURES FOR MITIGATING AGAINST CONVERSION PHENOMENA IN HIGH-ALUMINA CEMENTS - A manufacturing process of a cement product includes: (1) incorporating at least one additive into a high-alumina cement composition, wherein the at least one additive is selected from nitrate-containing salts, nitrite-containing salts, carbonate-containing salts, sulfate-containing salts, chloride-containing salts, and hydroxide-containing salts; and (2) curing the high-alumina cement composition to form the cement product. | 2016-04-21 |
20160107935 | LIQUID DISPERSANT COMPOSITION FOR GYPSUM - The present invention relates to a liquid dispersant composition for gypsum, containing (A) a particular polycarboxylic acid copolymer, a particular nitrogen-containing compound, such as a particular alkylamine, and water, and having pH of 7.0 or more and 13.0 or less at 20° C. | 2016-04-21 |
20160107936 | REFRACTORY OBJECT AND PROCESS OF FORMING A GLASS SHEET USING THE REFRACTORY OBJECT - A refractory object can include at least approximately 10 wt % Al | 2016-04-21 |
20160107937 | BUILDING PRODUCTS COMPOSITES AND METHODS - Methods of manufacturing composites are provided, including combining dihydrate calcium sulfate whiskers, hemihydrate calcium sulfate stucco, and water to form a slurry, and setting the slurry to form a composite having a natural porosity of about 60 volume percent or greater. Composites are also provided, including dihydrate calcium sulfate whiskers and dihydrate calcium sulfate crystals, and having a natural porosity of about 60 volume percent or greater. | 2016-04-21 |
20160107938 | ACCELERATOR FOR MINERAL BINDERS - A method for preparing a setting and hardening accelerator for mineral binders including a step of: (i) reacting a calcium compound CV with a silica sol SL, a molar ratio of Si:Ca being less than 0.1 during the reaction. | 2016-04-21 |
20160107939 | METHODS AND COMPOSITIONS FOR CONCRETE PRODUCTION - The invention provides compositions and methods directed to carbonation of a cement mix during mixing. The carbonation may be in a stationary mixer or a transportable mixer, such as a drum of a ready-mix truck. | 2016-04-21 |
20160107940 | CERAMIC MATRIX COMPOSITES AND METHODS FOR PRODUCING CERAMIC MATRIX COMPOSITES - A ceramic matrix composite includes a plurality of fibers embedded in a matrix. The composition of the matrix is selected to achieve a desired relationship between the mechanical and thermal properties of the matrix and the fibers. | 2016-04-21 |
20160107941 | METHOD FOR IMPREGNATING A POROUS BODY BY A SUSPENSION AND INSTALLATION FOR IMPLEMENTING SAME - The present invention relates to a method for impregnating a porous body ( | 2016-04-21 |
20160107942 | METHOD FOR RECYCLING A BYPRODUCT OF THE PHOSPHATE FERTILIZER INDUSTRY, SOIL CONDITIONER, AND SOIL CONDITIONER MANUFACTURING PROCESS - Industrial demand for hexafluorosilicic acid (H | 2016-04-21 |
20160107943 | Three-Part Plant Nutrient System - The present invention is incorporated in a three-part primary nutrient system for facilitating the growth of a plant in any growing media. The first part of the nutrient system comprises calcium and nitrogen and is devoid of phosphorus, potassium, magnesium, sulfur, and trace minerals. The second part of the nutrient system comprises nitrogen, phosphorus, potassium, magnesium, sulfur, and trace minerals and is devoid of calcium. The third part of the nutrient system comprises potassium, phosphorus, magnesium, sulfur, and trace minerals and is devoid of nitrogen and calcium. | 2016-04-21 |
20160107944 | SOIL CONDITIONER, AND SOIL CONDITIONER MANUFACTURING PROCESS - Industrial demand for hexafluorosilicic acid (H | 2016-04-21 |
20160107945 | BIOMATERIAL PROCESS AND APPARATUS - The invention relates to a process of manufacturing a growing medium from an initial material which is a by-product of a composting process and comprises a mixture of oversize biodegradable material and contaminants. The process comprises: removing contaminant objects from the initial material; removing mineral contaminants from the initial material; and subsequently defibrating the remaining material to produce a growing medium. | 2016-04-21 |
20160107946 | Producing Liquid Fertilizer in a Biogas Plant - A biogas plant produces both methane and liquid fertilizer by fermenting biomass. The plant includes a fermenter, a percolate tank and a sanitation tank located inside the percolate tank. Dry fermentation takes place in the fermenter and generates methane and a percolate. The percolate is circulated between the fermenter and the percolate tank. Percolate that is returned from the percolate tank to the fermenter is sprinkled over the biomass. A portion of the percolate is transferred from the percolate tank into the sanitation tank. The percolate in the sanitation tank is sanitized by heating to a Celsius temperature between 45° and 65° for a period of at least five days. The percolate in the sanitation tank is heated using both a heating device in the sanitation tank as well as heat generated from a thermophilic fermentation reaction occurring in the percolate tank. The sanitized percolate is used as liquid fertilizer. | 2016-04-21 |
20160107947 | SOLVENT SYSTEMS FOR DICYANDIAMIDE AND/OR ALKYL THIOPHOSPHORIC TRIAMIDE AND USE IN AGRICULTURAL APPLICATIONS - An inhibitor composition contains dicyandiamide as a nitrification inhibitor, alkyl thiophosphoric triamide as a urease inhibitor, or a combination thereof, dissolved in a liquid medium comprising an organic solvent selected from, among others, one or more polar aprotic solvents, including one or more organophosphates, amine solvents, heterocyclic alcohol solvents, and mixtures thereof, is useful in making fertilizer compositions and in a method of fertilizing target plants. | 2016-04-21 |
20160107948 | MECHANICALLY ACTIVATED METAL FUELS FOR ENERGETIC MATERIAL APPLICATIONS - The invention provides mechanically activated metal fuels for energetic material applications. An exemplary embodiment involves mechanically treating micrometer-sized particles of at least one metal with particles of at least one fluorocarbon to form composite particles containing the at least one metal and the at least one fluorocarbon. | 2016-04-21 |
20160107949 | COMPOSITIONS USABLE AS FLARE COMPOSITIONS, COUNTERMEASURE DEVICES CONTAINING THE FLARE COMPOSITIONS, AND RELATED METHODS - A composition that includes a fuel and a perfluoropolyether (PFPE) is disclosed. The composition may be used as a flare composition in a countermeasure device. Countermeasure devices including the flare composition are also disclosed, as are methods of forming grains of the countermeasure device. | 2016-04-21 |
20160107950 | METAL HYDRIDE NANOPARTICLES - A nanoparticle of a decomposition product of a transition metal aluminum hydride compound, a transition metal borohydride compound, or a transition metal gallium hydride compound. A process of: reacting a transition metal salt with an aluminum hydride compound, a borohydride compound, or a gallium hydride compound to produce one or more of the nanoparticles. The reaction occurs in solution while being sonicated at a temperature at which the metal hydride compound decomposes. A process of: reacting a nanoparticle with a compound containing at least two hydroxyl groups to form a coating having multi-dentate metal-alkoxides. | 2016-04-21 |
20160107951 | DIGITAL MICROFLUIDIC PLATFORM FOR RADIOCHEMISTRY - Disclosed herein are methods of performing microchemical reactions and electro-wetting-on-dielectric devices (EWOD devices) for use in performing those reactions. These devices and method are particularly suited for preparing radiochemical compounds, particularly compounds containing | 2016-04-21 |
20160107952 | HIGH EFFICIENCY FUEL CELL - Fuel cell arrangement having an improved efficiency. The arrangement comprises one or more fuel cell units | 2016-04-21 |
20160107953 | MODULAR REFINING REACTOR AND REFINING METHODS - Methods and apparatus for refining feedstocks, such as crude or synthetic oil, and like feedstocks, are disclosed herein. In some embodiments, a reactor for refining a feedstock includes: a chamber having an inner volume to hold a liquid feedstock, a feedstock inlet port, a process gas inlet port, and an outlet port; a gas diffuser housed within the chamber and coupled to the process gas inlet port; and a radical generator coupled in fluid communication with the inner volume via the gas diffuser. In some embodiments, a method for refining feedstock includes: providing liquid feedstock to an inner volume of a reactor; flowing a radicalized process gas from a radical generator into the inner volume and into contact with the feedstock via a gas diffuser to fractionate the feedstock and produce one or more fractions of product in a vaporous mixture; and collecting a desired product from the vaporous mixture. | 2016-04-21 |
20160107954 | PROCESS FOR THE ISOMERIZATION OF C5/C6 HYDROCARBON CUTS WITH CHLORINATED COMPOUND RECYCLING - A process for the isomerization of a feed of hydrocarbon compounds containing C | 2016-04-21 |
20160107955 | PROCESS FOR PRODUCING A CHLORINATED C3-6 ALKANE - Disclosed is a process for producing a chlorinated C3-6 alkane comprising providing a reaction mixture comprising an alkene and carbon tetrachloride in a principal alkylation zone to produce chlorinated C3-6 alkane in the reaction mixture, and extracting a portion of the reaction mixture from the principal alkylation zone, wherein:
| 2016-04-21 |
20160107956 | PROCESSES FOR PRODUCING VERY HIGH PURITY 1,1,1,2,3-PENTACHLOROPROPANE - Disclosed is a process for preparing a highly pure 1,1,1,2,3-pentachloropropane product, comprising
| 2016-04-21 |
20160107957 | PROCESS FOR THE MANUFACTURE OF 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE BY LIQUID PHASE FLUORINATION OF 2-CHLORO-3,3,3-TRIFLUOROPROPENE - Process of catalytic fluorination in liquid phase of product 2-chloro-3,3,3-trifluoropropene into product 2-chloro-1,1,1,2-tetrafluoropropane, with an ionic liquid based catalyst. Process for manufacturing 2,3,3,3-tetrafluoropropene. | 2016-04-21 |
20160107958 | PROCESS FOR PRODUCING HIGHLY PURE CHLORINATED ALKANE - Disclosed is a process for producing highly pure chlorinated alkane in which a chlorinated alkene is contacted with chlorine in a reaction zone to produce a reaction mixture containing the chlorinated alkane and the chlorinated alkene, and extracting a portion of the reaction mixture from the reaction zone, wherein the molar ratio of chlorinated alkane:chlorinated alkene in the reaction mixture extracted from the reaction zone does not exceed 95:5. | 2016-04-21 |
20160107959 | PROCESS FOR THE PREPARATION OF FLUORINATED COMPOUNDS - A subject-matter of the invention is a process for the preparation of 2,3,3,3-tetrafluoro-1-propene which comprises the following stages: (i) hydrogenation of hexafluoropropylene to give 1,1,1,2,3,3-hexafluoropropane; (ii) dehydrofluorination of the 1,1,1,2,3,3-hexafluoropropane obtained in the preceding stage to give 1,2,3,3,3-pentafluoro-1-propene; (iii) hydrogenation of the 1,2,3,3,3-pentafluoro-1-propene obtained in the preceding stage to give 1,1,1,2,3-pentafluoropropane; and (iv) dehydrofluorination of the 1,1,1,2,3-pentafluoropropane obtained in the preceding stage to give 2,3,3,3-tetrafluoro-1-propene. Stages (ii) and (iv) are carried out using a water and potassium hydroxide mixture with the potassium hydroxide representing between 58 and 86% by weight of the mixture and at a temperature of between 110 and 180° C. | 2016-04-21 |
20160107960 | PROCESS FOR PREPARING A CHLORINATED ALKENE - Disclosed is a process for preparing a chlorinated alkene, comprising contacting a chlorinated alkane with a catalyst in a dehydrochlorination zone to produce a liquid reaction mixture comprising the chlorinated alkane and the chlorinated alkene, and extracting chlorinated alkene from the reaction mixture, wherein the concentration of the chlorinated alkene in the reaction mixture present in the dehydrochlorination zone is controlled such that the molar ratio of chlorinated alkene:chlorinated alkane is from 1:99 to 50:50. | 2016-04-21 |
20160107961 | PROCESS FOR THE PREPARATION OF METHANOL IN PARALLEL REACTORS - In a process for the preparation of methanolin parallel reactors, comprising the steps of (a) reacting carbon oxides and hydrogen in the presence of a methanol catalyst in a first methanol reactor to obtain a first methanol-containing effluent, (b) introducing and reacting unconverted synthesis gas in a second methanol reactor in the presence of a methanol catalyst to obtain a second methanol-containing effluent, the first methanol reactor and the second methanol reactor being connected in parallel, (c) combining the first and second effluent, and (d) cooling and separating the combined and cooled effluent into a methanol-containing liquid phase and unconverted synthesis gas, the methanol catalyst in the first methanol reactor is indirectly cooled by boiling water and the methanol catalyst in the second methanol reactor is either directly or indirectly cooled by the unconverted synthesis gas prior to conversion into the second effluent. | 2016-04-21 |
20160107962 | PROCESS OF REMOVING HEAT - The present invention provides an improved process for removing heat from an exothermic reaction. In particular, the present invention provides a process wherein heat can be removed from multiple reaction trains using a common coolant system. | 2016-04-21 |
20160107963 | RECYCLING GAS TO HEAT THE HYDRODESULPHURIZATION SECTION - In one aspect, the present invention provides a method for recycling natural gas during a reformer startup in a methanol plant. The method comprises recycling natural gas from a point before entry into the natural gas saturator where the natural gas is recycled until the natural gas reaches a desired temperature. | 2016-04-21 |
20160107964 | METHOD FOR CONDENSING WATER-SOLUBLE ORGANIC MATTER AND DEVICE FOR CONDENSING WATER-SOLUBLE ORGANIC MATTER - A method and a device for condensing a water-soluble organic matter, which can collect a highly concentrated water-soluble organic matter, save energy, and reduce cost of the device by reducing a membrane area. | 2016-04-21 |
20160107965 | PROCESS FOR THE SEPARATION OF ALCOHOLS - The invention provides a process for the recovery of a first alcohol from a stream comprising two or more alcohols, said process comprising the steps of providing a stream comprising two or more alcohols, providing a solvent stream, combining said stream comprising two or more alcohols with said solvent stream in the presence of water and recovering at least a portion of the first alcohol by liquid-liquid extraction. | 2016-04-21 |
20160107966 | PROCESS FOR THE SEPARATION OF 1,4-BUTANEDIOL AND CO-PRODUCTS - The present invention provides a process for the recovery of 1,4-butanediol and at least one co-product selected from γ-butyrolactone, n-butanol and tetrahydrofuran from an aqueous stream, said process comprising the steps of providing the aqueous stream, providing a first solvent stream, combining said aqueous stream with said first solvent stream and recovering at least a portion of the 1,4-butanediol and at least a portion of at least one of the co-products by liquid-liquid extraction. | 2016-04-21 |
20160107967 | METHOD FOR THE DEPOLYMERIZATION OF LIGNIN - A catalytic method is disclosed for the valorization of lignin. The method comprises subjecting lignin to a catalyzed hydrothermal conversion reaction, said reaction being conducted in the presence of water at an alkaline pH>8 and a temperature of 200° C.-300° C., under the influence of a noble metal catalyst comprising a carbon support. The same reaction can also be applied to subsequently defunctionalize one or more phenolic compounds, notably guaiacol, so as to produce six-membered cyclic hydrocarbons, such as phenol. | 2016-04-21 |
20160107968 | METHOD FOR PRODUCING ACROLEIN - The present invention relates to a process for preparing acrolein from propylene by catalytic gas phase oxidation with molecular oxygen (for example air). The invention further relates to the use of particular propylene-containing starting materials, for example refinery grade propylene, for preparation of acrolein. | 2016-04-21 |
20160107969 | METHOD FOR PRODUCING AN OMEGA-HALO-2-ALKYNAL - Provided is a method for industrially producing a conjugated Z-alken-yn-yl acetate such as Z-13-hexadecen-11-yn-yl acetate which is a sex pheromone component of a pine processionary moth, and an intermediate for the conjugated Z-alken-yn-yl acetate under mild conditions at a high yield. More specifically, provided is a method for producing a conjugated Z-alken-yn-yl acetate (5) comprising the steps of: reacting an ω-halo-2-alkynal (1) with an alkylidene triphenylphosphorane (3) through a Wittig reaction to obtain a conjugated Z-alken-yn-yl halide (4), and acetoxylating the conjugated Z-alken-yn-yl halide (4) into a conjugated Z-alken-yn-yl acetate (5). | 2016-04-21 |
20160107970 | Process for Producing Phenol and/or Cyclohexanone - In a process for producing phenol and/or cyclohexanone, cyclohexylbenzene is contacted with an oxygen-containing gas in the presence of an oxidation catalyst under oxidation conditions effective to produce an oxidation effluent comprising cyclohexylbenzene hydroperoxide. At least a portion of the oxidation effluent is then subjected to a concentrating step to produce a cleavage feed having a higher concentration of cyclohexylbenzene hydroperoxide than the oxidation effluent. A cleavage reaction mixture comprising the cleavage feed is then contacted with a solid acid catalyst in a cleavage reaction zone under conditions effective to produce a cleavage product comprising phenol and cyclohexanone. | 2016-04-21 |
20160107971 | HEAT MANAGEMENT PROCESS - A method of managing the heat of a chemical reaction process. | 2016-04-21 |
20160107972 | IONIC LIQUID COMPOSITION - The present disclosure provides a composition for preparing aryl carboxylic acid; said composition comprising: at least one ionic liquid, at least one catalyst, at least one non-oxidizable polar solvent, and at least one oxidizable multi-alkylated arylene compound with no two successive ring positions bearing alkyl group. The present disclosure also provides a process for preparing aryl carboxylic acid. | 2016-04-21 |
20160107973 | SYNTHESIS OF INTERMEDIATES FOR PRODUCING PROSTACYCLIN DERIVATIVES - The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin derivatives, such as treprostinil. | 2016-04-21 |
20160107974 | Process For Production Of Acrylic Acid Or Its Derivatives - Processes for the catalytic dehydration of hydroxypropionic acid, hydroxypropionic acid derivatives, or mixtures thereof to acrylic acid, acrylic acid derivatives, or mixtures thereof with high yield and selectivity and without significant conversion to undesired side products, such as, acetaldehyde, propanoic acid, and acetic acid, are provided. The processes can be carried out either in a gas phase or in a liquid phase. | 2016-04-21 |
20160107975 | PROCESS FOR THE SEPARATION OF FORMIC ACID FROM METHYLTETRAHYDROFURAN - The invention relates to a process to separate formic acid from methyltetrahydrofuran (MTHF) said process comprising subjecting a composition comprising formic acid and MTHF to distillation, characterized in that the process comprises adding water to said distillation. This allows for cost-efficient recovery and recycling of MTHF, for example in process to produce and recover formic acid from a biomass hydrolysate. | 2016-04-21 |
20160107976 | METHOD OF PRODUCING ESTOLIDE HAVING HIGH STRUCTURAL STABILITY - Disclosed is a method of producing an estolide having high structural stability, including: a) preparing a fatty acid mixture from biomass-derived oil; b) separating the fatty acid mixture into a C16 fatty acid and a C18 fatty acid; c) converting the C18 fatty acid into a C18 or C17 linear internal olefin; and d) subjecting the C18 or C17 linear internal olefin and the C16 fatty acid to an estolide reaction, thus obtaining an estolide. | 2016-04-21 |
20160107977 | METHODS OF SYNTHESIS OF INGENOL AND INTERMEDIATES THEREOF - The present invention relates generally to methods of synthesis of diterpene heterocylic compounds. More particularly, the present invention relates to efficient methods of synthesis of ingenol (Formula (21), CAS 30220-46-3), from a compound of formula (1). The present invention also provides for various advantageous intermediates along the synthetic route of ingenol. Efficient synthesis of ingenol is important in the design and synthesis of related analogues, such as ingenol-3-angelate. | 2016-04-21 |
20160107978 | METHOD FOR PRODUCING A CONJUGATED Z-ALKEN-YN-YL ACETATE - Provided is a method for industrially producing a conjugated Z-alken-yn-yl acetate such as Z-13-hexadecen-11-yn-yl acetate which is a sex pheromone component of a pine processionary moth, and an intermediate for the conjugated Z-alken-yn-yl acetate under mild conditions at a high yield. More specifically, provided is a method for producing a conjugated Z-alken-yn-yl acetate (5) comprising the steps of: reacting an ω-halo-2-alkynal (1) with an alkylidene triphenylphosphorane (3) through a Wittig reaction to obtain a conjugated Z-alken-yn-yl halide (4), and acetoxylating the conjugated Z-alken-yn-yl halide (4) into a conjugated Z-alken-yn-yl acetate (5). | 2016-04-21 |
20160107979 | PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF - A process for preparing pentabromobenzyl acrylate through the reaction of pentahalobenzyl halide with a salt of acrylic acid in a water-immiscible solvent, wherein said salt is in aqueous form and the reaction is carried out in the presence of a phase transfer catalyst. A process for polymerizing the pentabromobenzyl acrylate in halogenated aromatic solvent and the poly(pentabromobenzyl acrylate) obtained are also disclosed. | 2016-04-21 |
20160107980 | CROSS METATHESIS OF POLY-BRANCHED POLY-OLEFINS - This invention describes processes to make products by cross metathesis of functionalized or non-functionalized olefins with poly-branched poly-olefins such as terpenes (e.g., farnesene(s), α-farnesene, β-farnesene, β-myrcene, etc.) and compositions made by such methods. More particularly, the present invention relates to methods of making (i) cross metathesis products by a cross metathesis reaction between at least one hydrovinylated olefinic substrate and at least one hydrovinylated cross metathesis substrate in the presence of at least one olefin metathesis catalyst; (ii) cross metathesis products by a cross metathesis reaction between at least one hydrovinylated olefinic substrate and at least one cross metathesis substrate in the presence of at least one olefin metathesis catalyst; and (iii) cross metathesis products by a cross metathesis reaction between at least one olefinic substrate and at least one hydrovinylated cross metathesis substrate in the presence of at least one olefin metathesis catalyst; as well as compositions made by such methods. | 2016-04-21 |
20160107981 | POLYMER DEGRADATION - A method of degrading a polymer into oligomers and/or monomers in a solvent, using a catalyst, and a functionalized magnetic particle comprising a catalyst being capable of degrading the polymer into oligomers and/or monomers. The present method and particle provide a high selectivity and a high conversion ratio. | 2016-04-21 |
20160107982 | NOVEL CHEMICAL COMPOUNDS DERIVED FROM NORMEMANTINE AND USE OF SAME IN THE MEDICAL FIELD - The present invention concerns novel chemical compounds corresponding to formulae (I) and (II): (I) (II) which, when marked with fluorine-18, can be used as markers of NMDA receptors for carrying out studies with a scanner. | 2016-04-21 |
20160107983 | AN IMPROVED PROCESS FOR THE PREPARATION OF 3-ARYLOXY-3-PHENYLPROPYLAMINE AND SALT THEREOF - The present invention relates to an industrially feasible and economically viable process for the preparation of 3-aryloxy-3-phenylpropylarnine and salt of formula I thereof. | 2016-04-21 |
20160107984 | MODULATOR - The present disclosure relates to a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein Z is selected from OH, NHCH | 2016-04-21 |
20160107985 | Compositions and Methods Relating to Ionic Salts of Peptides - The present invention relates to compounds of Formula I, compositions containing same, and methods of use. | 2016-04-21 |
20160107986 | IMPROVED METHOD FOR PRODUCING SPECIFIC OXIMES AND OXIMETHERS - Method for preparing certain oximes and oxime O-methyl ethers by reacting poorly water-soluble carbonyl compounds with salts of hydroxylamine or hydroxylamine O-methyl ether or the free base of hydroxylamine in the presence of certain phosphoric esters or salts thereof of the formula (I) | 2016-04-21 |
20160107987 | METHOD FOR PREPARING URETHANE (METH)ACRYLATES - Described is a process for preparing urethane (meth)acrylates. In a first step, a hydroxyalkyl (meth)acrylate is reacted with a lactone (B) in the presence of at least one zinc compound and/or bismuth compound (C) to produce a bismuth-containing product, and, in a further step, the bismuth-containing product is reacted with at least one cycloaliphatic or asymmetric aliphatic diisocyanate (D). | 2016-04-21 |
20160107988 | Tetracycline Compounds - The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I), or a pharmaceutically acceptable salt thereof, and its therapeutic use. | 2016-04-21 |
20160107989 | A PROCESS FOR PREPARATION OF PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES - The present invention provides pyrroles having hypolipidemic hypocholesteremic activities. The invention provides saroglitazar and its pharmaceutically acceptable salts, hydrates, solvates, polymorphs or intermediates thereof. The invention also provides a process for the preparation of saroglitazar. The invention further provides intermediates as well process for preparation thereof. | 2016-04-21 |
20160107990 | 4-(5-(4-CHLOROPHENYL)-2-(2-CYCLOPROPYLACETYL)-1,4-DIMETHYL-1H-PYRROL-3-YL)- BENZENESULFONAMIDE AS ALPHA 7 NACHR MODULATOR - Disclosed are an alpha 7 nAChR receptor modulator compound, 4-(5-(4-chlorophenyl)-2-(2-cyclopropylacetyl)-1,4-dimethyl-1H-pyrrol-3-yljbenzenesulfonamide, its tautomeric form, its pharmaceutically acceptable salts, pharmaceutical compositions comprising the compound or a salt thereof, and a method of treating various diseases, disorders or conditions, for example, Alzheimer's disease, mild cognitive impairment, senile dementia, vascular dementia, dementia of Parkinson's disease, and attention deficit disorder. | 2016-04-21 |
20160107991 | PROCESSES AND INTERMEDIATES FOR PREPARING INDOLE PHARMACEUTICALS - The invention described herein pertains to processes and intermediates for preparing indole containing pharmaceuticals, particularly to processes and intermediates for preparing selective estrogen receptor modulators, such as bazedoxifene. | 2016-04-21 |
20160107992 | INTERMEDIATES USEFUL FOR THE PREPARATION OF SAXAGLIPTIN - Intermediates useful for the synthesis of saxagliptin and their preparationare described. | 2016-04-21 |
20160107993 | POLYMORPHIC FORMS OF ST-246 AND METHODS OF PREPARATION - Polymorph forms of 4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl)-benzamide are disclosed as well as their methods of synthesis and pharmaceutical compositions. | 2016-04-21 |
20160107994 | HETEROCYCLIC AMPHOTERIC COMPOUNDS - Disclosed are a variety of amphoteric compounds having a heterocyclic quaternary nitrogen group. The heterocycle includes pyridines, piperidines, and pyrrolidines, and is linked to the hydrophobe via either an amide or an ester linkage. These heterocyclic amphoteric compounds can be advantageously prepared in high yield and purity by a two-step chemoenzymatic process, and have excellent surfactant properties. | 2016-04-21 |
20160107995 | HISTONE DEMETHYLASE INHIBITORS - The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like. | 2016-04-21 |
20160107996 | Mitochondrial Aldehyde Dehyrogenase-2 Modulators and Methods of Use Thereof - The present disclosure provides compounds of formula (I) that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity, and methods of preparing these compounds. | 2016-04-21 |
20160107997 | CXCR7 RECEPTOR MODULATORS - The present invention relates to derivatives of formula (I) | 2016-04-21 |
20160107998 | A PROCESS FOR PREPARING IVABRADINE - The invention refers to a process for preparing ivabradine, in particular a process for preparing an ivabradine salt. | 2016-04-21 |
20160107999 | SUBSTITUTED AZADIBENZOCYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS - The invention relates to a substituted azadibenzocyclooctyne compound according to Formula (5): The invention also relates to a conjugate wherein a substituted azadibenzocyclooctyne according to the invention is conjugated to a label, and to the use of these conjugates for bioorthogonal labeling, imaging or modification of a target molecule, e.g. surface modification. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene. | 2016-04-21 |
20160108000 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES - The present invention relates to a novel process for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives from α,α-dihaloamines. | 2016-04-21 |
20160108001 | PROCESS FOR THE STEREOSELECTIVE PREPARATION OF A PYRAZOLE-CARBOXAMIDE - The present invention relates to a process for the enantioselective preparation of the compound of formula (Ib), which process comprises a) reducing the (E)- or (Z)-form of a compound of formula (II), with an enantioselective reagent to a compound of formula (IIIa), and b) acylating the compound of formula (IIIa) with the compound of formula (IV), or c) coupling the compound of formula (IV) with the compound of formula (II), to give a compound of formula (V) and d) reducing compound of formula (V) in the presence of hydrogen, a catalyst and a chiral ligand, to the compound of formula (Ib). | 2016-04-21 |
20160108002 | UNIVERSAL READER MOLECULE FOR RECOGNITION TUNNELING - Some embodiments of the present disclosure are directed to a compound 5(6)-mercapto-1H-benzo[d]imidazole-2-carboxamide (“BIA”) which yields enhanced signals for recognition tunneling. Other embodiments are directed toward methods for producing such compounds as well as apparatuses and systems which utilize such compounds for recognition tunneling for molecule identification/sequencing (for example). | 2016-04-21 |
20160108003 | SULPHATE SALTS OF N-(3-(4-(3-(DIISOBUTYLAMINO)PROPYL)PIPERAZIN-1-YL)PROPYL)-1H-BENZO[d]IMID- AZOL-2-AMINE, PREPARATION THEREOF AND USE OF THE SAME - The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases. | 2016-04-21 |
20160108004 | TREATMENT OR PREVENTION OF NEURODEGENERATIVE DISORDERS USING MENTHOL, LINALOOL AND/OR ICILIN - Compositions for treatment or prevention of neurodegenerative disorders are provided, and the compositions contain a therapeutically effective amount of a compound selected from the group consisting of Menthol, Linalool, Icilin and combinations thereof. Methods for treatment or prevention of neurodegenerative disorders are also provided, and the methods include administering such compositions. | 2016-04-21 |
20160108005 | TREATMENT OR PREVENTION OF DEPRESSION USING MENTHOL AND/OR ICILIN - Compositions for treatment or prevention of depression are provided, and the compositions contain a therapeutically effective amount of a compound selected from the group consisting of Menthol, Icilin and combinations thereof. Methods for treatment or prevention of depression are also provided, and the methods include administering such compositions. | 2016-04-21 |
20160108006 | Synthesis Method of Organometallic Complex, Synthesis Method of Pyrazine Derivative, 5,6-Diaryl-2-Pyrazyl Triflate, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device - Provided is a 5,6-diaryl-2-pyrazyl triflate, its synthetic method, and a method for synthesizing an organometallic complex having a triarylpyrazine ligand from the 5,6-diaryl-2-pyrazyl triflate. The triflate is readily obtained from the corresponding 5,6-diarylpyrazin-2-ol, and the palladium-catalyzed coupling of the 5,6-diaryl-2-pyrazyl triflate with an arylboronic acid derivative leads to a high yield of a triarylpyrazine derivative having high purity. The use of the triarylpyrazine derivative in the reaction with a metal compound such as a metal chloride results in an ortho-metallated organometallic complex with high purity. The high purity of the organometallic complex contributes to the extremely high durability of a light-emitting element. | 2016-04-21 |
20160108007 | SYNTHESIS OF SYRBACTIN PROTEASOME INHIBITORS - The disclosure relates generally to methods for the preparation of a family of natural compounds, the syrbactins and their analogs. | 2016-04-21 |
20160108008 | Substituted N-(Tetrazol-5-yl)- and N-(Triazol-5-yl)arylcarboxamide Compounds and Their Use as Herbicides - N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamides of formula I and their use as herbicides, | 2016-04-21 |
20160108009 | Novel formulation of metaxalone - The present invention relates to methods for producing particles of metaxalone using dry milling processes as well as compositions comprising metaxalone, medicaments produced using metaxalone in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of metaxalone administered by way of said medicaments. | 2016-04-21 |
20160108010 | HUMIC ACID DERIVATIVES AND METHODS OF PREPARATION AND USE - Disclosed are antioxidative natural compounds, their salts, chelates and cleavage derivatives that exhibit a superior combination of properties. The compounds can be used for a variety of purposes, including the stabilization of polymers. The compounds can be prepared by substantially cleaving a humic acid of formula I followed by esterification to provide at least one antioxidant compounds of formula V, formula VI, formula VII, formula VIII, salts thereof, or chelates thereof. | 2016-04-21 |
20160108011 | Novel Substituted Bicyclic Aromatic Compounds as S-Nitrosoglutathione Reductase Inhibitors - The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same. | 2016-04-21 |
20160108012 | PROSTAGLANDIN CONJUGATES AND DERIVATIVES FOR TREATING GLAUCOMA AND OCULAR HYPERTENSION - Prostaglandin conjugates and derivatives and methods for their use to treat glaucoma and/or lower intraocular pressure are disclosed. Additionally, ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma and elevated intraocular pressure are disclosed. Such compositions comprise an effective amount of prostaglandin conjugates or derivatives of the present invention. | 2016-04-21 |
20160108013 | PROCESSES FOR SELECTIVE EXTRACTION OF UNSAPONIFIABLE MATERIALS FROM RENEWABLE RAW MATERIALS BY REACTIVE TRITURATION IN THE PRESENCE OF A COSOLVENT - A method for extracting an unsaponifiable fraction from a renewable raw material, includes the reactive trituration of the raw material dehydrated in the presence of at least one polar organic solvent including at least one light alcohol, at least one non-polar cosolvent immiscible with the light alcohol and at least one catalyst, resulting in the formation of a polar organic phase enriched with lipids functionalized with one or more function(s) chosen from hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine functions, and of a non-polar organic phase enriched with lipids containing no or few hydroxyl, epoxide, ketone, thiol, aldehyde, ether and amine function(s), and thereafter the concentration of the organic phases. | 2016-04-21 |
20160108014 | NOVEL ACID DIANHYDRIDE, METHOD FOR PREPARING SAME, AND POLYIMIDE PREPARED THEREFROM - The present invention relates to a novel acid dianhydride, a method for preparing the same, and a polyimide prepared therefrom. More specifically, the acid dianhydride according to the present invention is useful as a colorless transparent polyimide unit exhibiting excellent thermal stability and a low dielectric ratio, and the polyimide of the present invention has excellent solubility to an organic solvent compared with the conventional polyimide. | 2016-04-21 |
20160108015 | Carbofluorescein Lactone Ion Indicators and Their Applications - Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations are provided. | 2016-04-21 |
20160108016 | Novel Cannabinergic Compounds and Uses Thereof - Disclosed are compounds and compositions that modulate cannabinoid receptors, methods of modulating cannabinoid receptors, and methods of treating various disorders related to the modulation of cannabinoid receptors. This disclosure is directed to methods of treating cannabinoid dependence, neuropathy, inflammation, glaucoma, a neurodegenerative disorder, a motor function disorder, a gastrointestinal disorder, hypothermia, emesis, loss of appetite, or anorexia associated with AIDS. | 2016-04-21 |
20160108017 | PROCESS FOR PREPARING AN 1,2-ALKYLENE CARBONATE - The invention relates to a process for preparing an 1,2-alkylene carbonate comprising
| 2016-04-21 |
20160108018 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF - Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described. | 2016-04-21 |
20160108019 | INHIBITORS OF KRAS G12C MUTANT PROTEINS - Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I): | 2016-04-21 |
20160108020 | QUINAZOLINEDIONE DERIVATIVES AS PARP INHIBITORS - The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) | 2016-04-21 |
20160108021 | PYRIDONE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES - This invention relates to pyridone derivatives, processes for their preparation, phamaceutical compositions, and their use in therapy. | 2016-04-21 |
20160108022 | TRIAZOLE COMPOUNDS AND THEIR USE AS GAMMA SECRETASE MODULATORS - The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of Aβ-related diseases. | 2016-04-21 |
20160108023 | Novel Compound - There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. | 2016-04-21 |
20160108024 | BILATERALLY-SUBSTITUTED TRICYCLIC COMPOUNDS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS TYPE-1 (HIV-1) INFECTION AND OTHER DISEASES - The invention relates to novel bilaterally-substituted tricyclic compounds and pharmaceutical compositions containing them, for use as medicaments. | 2016-04-21 |