16th week of 2011 patent applcation highlights part 32 |
Patent application number | Title | Published |
20110092353 | DURABLE GLASS-CERAMIC HOUSINGS/ENCLOSURES FOR ELECTRONIC DEVICE - The invention relates glass ceramic articles suitable for use as electronic device housing or enclosures which comprise a glass-ceramic material. Particularly, a glass-ceramic article housing/enclosure comprising a glass-ceramic material exhibiting both radio and microwave frequency transparency, as defined by a loss tangent of less than 0.5 and at a frequency range of between 15 MHz to 3.0 GHz, a fracture toughness of greater than 1.5 MPa·m | 2011-04-21 |
20110092354 | SYNTHETIC SILICA GLASS WITH UNIFORM FICTIVE TEMPERATURE - A method of making a silica glass having a uniform fictive temperature. The glass article is heated at a target fictive temperature, or heated or cooled at a rate that is less than the rate of change of the fictive temperature, for a time that is sufficient to allow the fictive temperature of the glass to come within 3° C. of the target fictive temperature. The silica glass is then cooled from the target fictive temperature to a temperature below the strain point of the glass at a cooling rate that is greater than the relaxation rate of the glass at the target fictive temperature. The silica glass has a fictive temperature that varies by less than 3° C. after the annealing step. A silica glass made by the method is also described. | 2011-04-21 |
20110092355 | RECLAIMING APPARATUS AND RECLAIMING METHOD - A reclaiming apparatus | 2011-04-21 |
20110092356 | CATALYTIC STRUCTURES INCLUDING CATALYST MATERIALS IN POROUS ZEOLITE MATERIALS, AND METHODS OF FORMING SAME - Catalytic structures include a catalytic material disposed within a zeolite material. The catalytic material may be capable of catalyzing a formation of methanol from carbon monoxide and/or carbon dioxide, and the zeolite material may be capable of catalyzing a formation of hydrocarbon molecules from methanol. The catalytic material may include copper and zinc oxide. The zeolite material may include a first plurality of pores substantially defined by a crystal structure of the zeolite material and a second plurality of pores dispersed throughout the zeolite material. Systems for synthesizing hydrocarbon molecules also include catalytic structures. Methods for synthesizing hydrocarbon molecules include contacting hydrogen and at least one of carbon monoxide and carbon dioxide with such catalytic structures. Catalytic structures are fabricated by forming a zeolite material at least partially around a template structure, removing the template structure, and introducing a catalytic material into the zeolite material. | 2011-04-21 |
20110092357 | SILICA-COATED ALUMINA ACTIVATOR-SUPPORTS FOR METALLOCENE CATALYST COMPOSITIONS - Silica-coated alumina activator-supports, and catalyst compositions containing these activator-supports, are disclosed. Methods also are provided for preparing silica-coated alumina activator-supports, for preparing catalyst compositions, and for using the catalyst compositions to polymerize olefins. | 2011-04-21 |
20110092358 | VULCANIZATION-ACCELERATING MIXTURE - The present invention relates to a mixture which can be used as vulcanization accelerator, to a process for producing the mixture and to use of the mixture, to vulcanizates which comprise the said mixtures or which comprise corresponding individual constituents of the mixture, and also to vulcanizates which are produced with use of the said mixture. | 2011-04-21 |
20110092359 | PHOTOCATALYTIC TITANIUM OXIDE SOL, AND COATING COMPOSITION AND MEMBER USING THE SAME - A photocatalytic coating composition comprising photocatalytic titanium oxide, silver, copper and a quaternary ammonium hydroxide. The photocatalytic coating composition may include a photocatalytic titanium oxide sol dispersed in a binder. Furthermore, a photocatalytic member includes a substrate having a surface coated with the photocatalytic coating composition. The photocatalyst coating composition can contain highly antibacterial silver by skillfully utilizing copper and a quaternary ammonium hydroxide, and accordingly can show an antibacterial effect not only in a dark place simply due to silver, but also a higher antibacterial effect in a conventional application of employing ultraviolet sterilization by concomitantly using the photocatalyst titanium oxide sol according to the present invention and an ultraviolet sterilizer. | 2011-04-21 |
20110092360 | PROCESS FOR SULFURIZING HYDROCARBON TREATMENT CATALYSTS - The present invention relates to a process for sulfurizing a hydrocarbon treatment catalyst, comprising:
| 2011-04-21 |
20110092361 | Sulfur-Tolerant Catalyst Systems - Methods for improving the sulfur-tolerance of nickel-based catalyst systems, as well as the improved catalyst systems, are disclosed. The methods can include adding praseodymium alone, or in combination with ruthenium and/or cerium, to a nickel-based catalyst system, thereby inhibiting sulfur poisoning of the catalyst system. Improved catalyst systems can have an added amount of praseodymium alone, or in combination with ruthenium and/or cerium, sufficient to inhibit poisoning of the system by sulfur. | 2011-04-21 |
20110092362 | Porous Carbon Material and a Method of Production Thereof - Disclosed is a method for producing a porous carbon material comprising: heating a cured phenolic resin complex lump, including 150 to 450 parts by weight of sodium hydroxide and/or potassium hydroxide per 100 parts by weight of phenolic resin, at a temperature of 420 to 850° C. in a non-oxidizing atmosphere to obtain carbonized material; and washing and removing sodium hydroxide and potassium hydroxide included in the carbonized material. According to the present invention, there can be provided a porous carbon material, including large volumes of subnano-pores having a diameter of in a range of 0.45 to 1.0 nm with a sharp distribution, which is particularly useful as a gaseous adsorbent. | 2011-04-21 |
20110092363 | POROUS METAL OXIDE PARTICLES - Preparing porous particles includes forming a gel including a first liquid and an oxygen-containing compound of a metal, semi-metal, metalloid, or semi-conductor, including an oxide, hydroxide, alkoxide, oxohydroxide, oxoalkoxide, oxo salt, or oxo salt hydrate of the metal, semi-metal, metalloid, or semi-conductor; contacting the gel with a combustible liquid to form a combustible gel; and initiating combustion of the combustible gel to form a substance including porous metal, semi-metal, metalloid, or semi-conductor oxide particles. The combustible liquid can include a volatile solvent. The porous particles have open pores with a range of nanoscale pore sizes. The porous particles may be treated further to form, for example, a composite. | 2011-04-21 |
20110092364 | OLIGOMERIC SPIROPYRANS FOR ERASABLE MEDIUM APPLICATIONS - Exemplary embodiments provide compositions and methods for making and using an erasable medium that can contain oligomeric photochromic materials such as spiropyran oligomers, wherein the oligomeric photochromic material can include a plurality of photochromic groups such as spiropyrans covalently connected together by one or more linkers. | 2011-04-21 |
20110092365 | THERMOSENSITIVE RECORDING MATERIAL - A thermosensitive recording material including, on a support having a type D durometer hardness of 40 or more as defined in accordance with ISO 7619:2004, and sequentially from the support side, an undercoating layer having a dynamic microhardness at 25° C. of 5.0 mN or less; and a thermosensitive color-forming layer containing an electron-donating dye precursor and an electron-accepting compound for thermal color-formation of the electron-donating dye precursor. | 2011-04-21 |
20110092366 | Ternary Herbicidal Compositions Comprising Aminopyralid and Imazamox - Herbicidally active compositions, which comprise 4-amino-3,6-dichloropyridine-2-carboxylic acid (common name: aminopyralid), 2-[(RS)-4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl]-5-methoxymethylnicotinic acid (common name: imazamox)
| 2011-04-21 |
20110092367 | Herbicidal Compositions Comprising 4-amino-3,6-dichloropyridine-2-carboxylic Acid - Herbicidally active compositions, which comprise 4-amino-3,6-dichloropyridine-2-carboxylic acid (herbicide A) and at least one herbicide B from the group of the lipid biosynthesis inhibitors, a method for controlling undesirable vegetation, their use for controlling undesirable vegetation, and formulations comprising such compositions. | 2011-04-21 |
20110092368 | 2,4,6-Phenyl-substituted cyclic ketoenols - The present invention relates to novel 2,4,6-phenyl-substituted cyclic ketoenols of the formula (I) | 2011-04-21 |
20110092369 | MICROCAPSULE COMPOSITION FOR INHIBITING AN ETHYLENE RESPONSE IN PLANTS, METHOD FOR PREPARING MICROCAPSULES, AND METHOD USING THE MICROCAPSULE COMPOSITION - Disclosed is a microcapsule composition for inhibiting an ethylene response in plants, which comprises a plurality of microcapsules, each including an agent for blocking an ethylene binding site in plants in an oil droplet, and a coating encapsulating the oil droplet and the agent for blocking the ethylene binding site in plants. A method for preparing microcapsules of an agent for blocking the ethylene binding site in plants, and a method for inhibiting an ethylene response in plants are also disclosed. | 2011-04-21 |
20110092370 | Surfactant Composition for Agricultural Chemicals - A surfactant composition for agricultural chemicals, containing fatty acid polyoxyalkylene alkyl ether expressed by the following general formula (I), | 2011-04-21 |
20110092371 | COOLING FLUID PATH STRUCTURE FOR SUPERCONDUCTION ROTATING MACHINE - Disclosed is a cooling fluid path structure for a superconducting rotating machine, which includes: a fixed inlet fluid path fixed together with the fluid supply means; a rotating inlet fluid path adjacently connected to an outlet of the fixed inlet fluid path, which is for transferring the cooling fluid transferred from the fixed inlet fluid path to a cooling fluid path inlet provided in the rotor while rotating together with the rotor; a rotating outlet fluid path rotating together with the rotor, to which the cooling fluid discharged from a cooling fluid path outlet of the rotor is transferred; and a fixed outlet fluid path adjacently connected to the rotating outlet fluid path, which is for transferring the cooling fluid transferred from the rotating outlet fluid path to the fluid supply means while being fixed together with the fluid supply means, wherein the rotating outlet fluid path and the fixed outlet fluid path are disposed in such a manner that they surround outside of the rotating inlet fluid path and the fixed inlet fluid path. | 2011-04-21 |
20110092372 | Methods of Affinity Maturing Antibodies - The invention relates to methods of affinity maturing antibodies. | 2011-04-21 |
20110092373 | SYSTEM FOR TRANSPORTING EMULSIONS FROM AN ARRAY TO A DETECTOR - System, including apparatus and methods, for performing droplet-based assays. The system may comprise a droplet transporter configured to pick up droplets from each emulsion of an array of reacted emulsions and to drive flow of the droplets through a detection region. The system also may comprise a detector configured to collect data related to one or more analytes from individual droplets of the reacted emulsions as such individual droplets travel through the detection region. The system further may comprise a controller programmed to determine, based on the data collected, an aspect of the one or more analytes in one or more samples included in droplets of the emulsions. | 2011-04-21 |
20110092374 | METHODS FOR PRODUCING SUBSTANTIALLY HOMOGENEOUS HYBRID OR COMPLEX N-GLYCANS IN METHYLOTROPHIC YEASTS - The present invention provides methods for effectively and efficiently converting methylotrophic yeast's heterogeneous high mannose-type N-glycosylation to mammalian-type N-glycosylation by disruption of an endogenous glycosyltransferase gene (OCH1) and step-wise introduction of heterologous glycosidase and glycosyltransferase activities. Each engineering step includes a number of stages: transformation with an appropriate vector, cultivation of a number of transformants, performance of sugar analysis and heterologous protein expression analysis, and selection of a desirable clone. The selected clone is then subjected to the next engineering step. | 2011-04-21 |
20110092375 | Deducing Exon Connectivity by RNA-Templated DNA Ligation/Sequencing - A technology is described that is capable of generating high-throughput sequencing (HTS) read length DNA products to accurately and reliably provide exon connectivity information for alternatively spliced isoforms. The method is not limited by the initial size of the isoform as the technology removes the template oligonucleotide sequence and a newly formed full length ligated product provides an HTS-compatible read length sequence that comprises information that corresponds to the consecutive order of the exons in the original template oligonucleotide. | 2011-04-21 |
20110092376 | SYSTEM FOR DROPLET-BASED ASSAYS USING AN ARRAY OF EMULSIONS - System, including method and apparatus, for performing droplet-based assays. In the method, an emulsion may be obtained that includes droplets packed closely together in a three-dimensional packing arrangement. Data related to an analyte may be collected from individual droplets of the reacted emulsion as such droplets travel serially through a detection region. | 2011-04-21 |
20110092377 | High throughput methods for analysis of contamination in environmental samples - Use of high throughput methods to analyze samples for toxic elements originating from industrial hygiene and environmental sampling are described. These methods utilize optical detection methods using plates with arrays and microwells. Methods to fabricate samples in such plates are described. The invention is particularly illustrated by demonstrating its applicability for analysis of beryllium by fluorescence and uranium by phosphorescence. This invention also discloses the use of improved filtration method and use of reagents with low background signals. | 2011-04-21 |
20110092378 | ISOLATION AND USE OF SOLID TUMOR STEM CELLS - A small percentage of cells within an established solid tumor have the properties of stem cells. These solid tumor stem cells give rise to both more tumor stem cells and to the majority of cells in the tumor that have lost the capacity for extensive proliferation and the ability to give rise to new tumors. Thus, solid tumor heterogeneity reflects the presence of tumor cell progeny arising from a solid tumor stem cell. | 2011-04-21 |
20110092379 | GENOTYPING METHOD AND MEANS THEREOF FOR USE IN TRACEABILITY SCHEMES - The invention discloses means and methods for genotyping an individual head of cattle. Individual's DNA is genotyped utilising the herein defined PCR SNaP-shot protocol. The protocol comprises two PCR steps where the first step (PCR1) includes adding primers (SEQ ID No. 1-30) and/or primers extended at their 5′ end with a common 10 base motif (ACGTTGGATG) to the PCR1 reaction. The second step (PCR2) includes adding extension primers (SEQ ID No. 31-45), and/or primers adjacent to corresponding specific SNPs. Further steps include producing amplicons from a PCR1 mixture comprising template DNA and the first primer set to yield PCR1 products, using PCR1 products as templates to a set of extension primers to yield PCR2 products. Size and colour separation is achieved by adding tails of different lengths to the PCR2 primers. PCR2 products are separated and the results compared with SNP profiles from the databank to obtain matching. | 2011-04-21 |
20110092380 | IMPROVED MOLECULAR-BIOLOGICAL PROCESSING EQUIPMENT - The invention relates to improved molecular-biological processing equipment and an improved method of processing biological samples. The invention combines the provision of biologically functional molecules such as nucleic acids and peptides and of derivatives or analogs of these two classes of molecules in miniaturized flow cells with the sequential addition of reagents or fluids and serves for the processing of biological samples, such as proteins, nucleic acids, biogenic small molecules such as e.g. metabolites, viruses or cells, which for this purpose are introduced into the miniaturized flow cells. The invention further relates to methods and to the use of the molecular-biological processing equipment according to the invention for the detection and/or for the isolation of nucleic acids; for sequencing; for point mutation analysis; for the analysis of genomes and/or chromosomes; for the production of synthetic nucleic acids; for the production of arrays of primers, probes and/or antisense molecules; and other analytical and synthetic methods. | 2011-04-21 |
20110092381 | DETECTION OF PLURALITY OF TARGETS IN BIOLOGICAL SAMPLES - Methods for detecting a plurality of targets in a biological sample are provided. The method comprises contacting the biological sample with a plurality of target-binding probes to form a plurality of target-bound probes, covalently attaching at least one of the target-bound probes to the biological sample, and observing the signals from the target-bound probes sequentially. An associated kit and device for detection of the plurality of targets are also provided. | 2011-04-21 |
20110092382 | Modified Nucleic Acid Probes - Oligonucleotide analogue arrays attached to solid substrates and methods related to the use thereof are provided. The oligonucleotide analogues hybridize to nucleic acids with either higher or lower specificity than corresponding unmodified oligonucleotides. Target nucleic acids which comprise nucleotide analogues are bound to oligonucleotide and oligonucleotide analogue arrays. | 2011-04-21 |
20110092383 | Method For Diagnosing Multiple Sclerosis - Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample. | 2011-04-21 |
20110092384 | COMPOSITIONS AND METHODS FOR PRODUCING CODED PEPTOID LIBRARIES - Embodiments of the invention are directed to a one-bead-two-compound method for the creation of encoded cyclic peptoid libraries. This scheme is useful for the creation of cyclic peptoid microarrays since only the cyclic peptoid, not the linear encoding molecule, contains an attachment residue and thus can be spotted onto an activated substrate. | 2011-04-21 |
20110092385 | COMPOSITIONS AND METHODS TO DETECT INFLUENZA VARIANTS - Methods and kits used in the detection of variants of the Influenza virus are disclosed, including variants that are resistant to treatment with antiviral compositions. | 2011-04-21 |
20110092386 | ISOLATING BIOLOGICAL MODULATORS FROM BIODIVERSE GENE FRAGMENT LIBRARIES - The present invention provides a method for identifying a modulator or mediator of a biological activity, which activity includes antigenicity and/or immunogenicity, said method comprising the step of:
| 2011-04-21 |
20110092387 | Expression profiling using microarrays - The invention provides novel compositions and methods for the analysis of gene expression (e.g., expression profiling) using microarray-based technology. In some embodiments of the invention, the novel methods use gene-specific as well as universal amplification primers during sample preparation, and the methods permit the simultaneous analysis of multiple samples on the same microarray. Furthermore, some embodiments of the invention incorporate barcode sequences into the amplified products, thereby permitting the use of generic arrays and generic labeled probes. | 2011-04-21 |
20110092388 | COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND THERAPY OF BREAST CANCER - The invention relates to newly discovered nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast cancers are provided. | 2011-04-21 |
20110092389 | METHODS OF DETECTING TARGETS ON AN ARRAY - The invention relates to methods of detecting a target analyte in a biological sample using composite microsphere arrays having first and second assay locations. Preferred target analytes include nucleic acid, and more specifically, nucleic acid having one or more single nucleotide polymorphisms (SNPs). | 2011-04-21 |
20110092390 | ASSESSMENT OF EFFECT OF AN AGENT ON A HUMAN BIOLOGICAL CONDITION USING RODENT GENE EXPRESSION PANELS - Rodent gene expression data, in particular, gene expression profiles, are created and used to predict the efficacy of therapeutic agents on human biological conditions. Gene Profile data sets are derived from rodent subject samples and include quantitative, substantially repeatable measures of a distinct amount of RNA or protein constituent(s) in a signature panel selected such that measurement of the constituent(s) enables measurement of a biological condition of interest in both human and rodent subjects. Such profile data sets may be used to predict the therapeutic efficacy of a therapeutic agent in humans. | 2011-04-21 |
20110092391 | PHAGE LAMBDA DISPLAY CONSTRUCTS - Bacteriophages in general and lambda phage in particular are powerful, flexible reagents who have yet to be exploited to their full potential. As discussed herein, the lambda phage head and/or genome comprises an easy to use and highly efficient delivery vehicle for delivering the expression products of a gene of interest systemically or to a particular tissue. | 2011-04-21 |
20110092392 | SYSTEM FOR FORMING AN ARRAY OF EMULSIONS - System, including apparatus and methods, for forming an array of emulsions. The system may comprise a plate including an array of emulsion production units. Each unit may include at least one first input well, a second input well, and an output well connected to the first and second input wells by channels that form a droplet generator. The system also may comprise a vacuum or pressure source configured to be connected operatively to wells of the plate to form a pressure drop between the input wells and the output well of each unit that is capable of driving a first fluid and a second fluid from respective first and second input wells of such unit and through the droplet generator, for collection as an emulsion in the output well of such unit. | 2011-04-21 |
20110092393 | METHOD OF REDUCING THE VISCOSITY OF HYDROCARBONS - Methods of treating hydrocarbon fluids to reduce the apparent viscosity of hydrocarbon fluids encountered in petroleum operations and reducing deposits within a well annulus or a pipeline are disclosed. The method comprises contacting such fluids with a hydrophobically modified polysaccharide to create water external emulsions. The disclosed hydrophobically modified polysaccharides have been demonstrated to reduce interfacial tension to below 65 mN/m and thereby improve the transportability of inherently viscous hydrocarbon fluids, such as heavy crude oils. | 2011-04-21 |
20110092394 | FLUORINATED CATIONIC SURFACTANT - A composition comprising a fluorinated pyridinium cationic compound of formula (I) | 2011-04-21 |
20110092395 | FLUORINATED VINYLIDENE CATIONIC SURFACTANT - A fluorinated pyridinium cationic compound of formula (I) | 2011-04-21 |
20110092396 | COPOLYMER FOR SHALE STABILIZATION AND METHOD OF USE - Embodiments disclosed herein relate to methods for stabilizing shales while drilling a wellbore into an earthen formation comprising circulating an aqueous based wellbore fluid in the wellbore while drilling through shales; wherein the aqueous-based wellbore fluid comprises a copolymer of acrylamide-type comonomers and at least one cationic comonomer. | 2011-04-21 |
20110092397 | Thermophilic Mannanohydrolase and Fracturing Fluids Containing the Same - A thermophilic mannanohydrolase enzyme may be used as an enzyme breaker for fracturing fluids containing hydratable polymers of guar and underivatized guar. The enzyme is effective in downhole temperatures exceeding 160° F. | 2011-04-21 |
20110092398 | VISCOELASTIC SURFACTANT FLUIDS AND RELATED METHODS OF USE - Viscoelastic surfactant based aqueous fluid systems useful as thickening agents in various applications, e.g. to suspend particles produced during the excavation of geologic formations. The surfactants are zwitterionic/amphoteric surfactants such as dihydroxyl alkyl glycinate, alkyl ampho acetate or propionate, alkyl betaine, alkyl amidopropyl betaine and alkylimino mono- or di-propionates derived from certain waxes, fats and oils. The thickening agent is used in conjunction with an inorganic water-soluble salt or organic additive such as phthalic acid, salicylic acid or their salts. | 2011-04-21 |
20110092399 | LUBRICATING GREASE COMPOSITION BASED ON IONIC LIQUIDS - The invention relates to the use of ionic liquids for production of water-resistant lubricating grease compositions, which are used in a temperature range from at least 30° C. to at least 180° C. and have good anticorrosion properties. | 2011-04-21 |
20110092400 | SOLID LUBRICANT AND PRODUCTION METHOD THEREOF - A method for producing a solid lubricant includes steps of preparing and coating. A phosphate aqueous solution prepared by the step of preparing is an aqueous solution containing at least one of aluminum dihydrogen phosphate and magnesium dihydrogen phosphate in an amount of 0.5 to 10% by mass. A graphite material is coated with a phosphate using the phosphate aqueous solution. The graphite material is used at a ratio of 40 to 50 parts by mass based on 100 parts by mass of the aqueous solution. | 2011-04-21 |
20110092401 | Gear oil having low copper corrosion properties - A gear oil additive composition and gear oil composition comprising a organic polysulfide having at least 30 wt % of a dialkyl polysulfide compound or mixture of dialkyl polysulfide compounds, a thiadiazole; and at least one ashless phosphorus-containing wear inhibitor compound is disclosed as having low yellow corrosion in axles and transmissions. | 2011-04-21 |
20110092402 | TRANSMISSION OIL COMPOSITION FOR AUTOMOBILE - A transmission oil composition for an automobile characterized in that it contains a base oil selected from the group consisting of a mineral oil, a synthetic oil and mixtures thereof; and a phosphate compound selected from the group consisting of (A) a zinc dithiophosphate having a hydrocarbon group, (B) a triaryl phosphate (C) a triaryl thiophosphate, and mixtures thereof at 0.1 to 15.0% by mass with respect to the total composition; wherein the composition has a volume resistivity of 1×10 | 2011-04-21 |
20110092403 | CYLINDER LUBRICANT FOR A TWO-STROKE MARINE ENGINE - The present invention relates to a cylinder lubricant having a BN determined according to standard ASTM D-2896 greater than or equal to 15, preferably greater than 20, preferably greater than 30, advantageously greater than 40 milligrams of potash per gram of lubricant, comprising:
| 2011-04-21 |
20110092404 | OVERBASED METAL CARBOXYLATE COMPLEX GREASE AND PROCESS FOR MAKING - Complex greases of overbased alkaline earth metal carboxylates are prepared by reacting an overbased alkaline earth metal salt of a fatty acid, wherein the alkaline earth metal salt has an alkaline earth metal content of at least 14.5% and a non-volatile matter content of at least 95% with conversion agents to form a grease precursor. The grease precursor is then reacted with complexing agents to form a predominantly vaterite containing non-Newtonian modified overbased metal carboxylate complex grease. | 2011-04-21 |
20110092405 | LIQUID CLEANSING COMPOSITIONS - A liquid cleansing composition comprising a glyceryl caprylate/caprate ester that provides excellent viscosity-building properties, as well as enhanced foaming properties. The glyceryl caprylate/caprate ester is preferably glyceryl caprylate/caprate, and is preferably obtained by esterifying glycerin with C8-C10 fatty acids derived from coconut or palm kernel oil. The cleansing composition also comprises one or more surfactants, and optional additives, and can be formulated into a body wash, shampoo, 2-in-1 shampoo, facial cleanser, or liquid hand soap. | 2011-04-21 |
20110092406 | PROCESS FOR MAKING A SECONDARY ALCOHOL CLEANING PRODUCT - A process for making a useful cleaning product from an alkoxylate of a secondary alcohol which comprises: (a) partially sulfating a secondary alcohol alkoxylate with sulfur trioxide in a falling film sulfation reactor at a molar ratio of sulfur trioxide to secondary alcohol alkoxylate of less than 0.9 to produce a mixture comprising a sulfuric acid ester of the secondary alcohol alkoxylate and secondary alcohol alkoxylate which may comprise at least 50 percent by weight of the sulfuric acid ester of the secondary alcohol alkoxylate, (b) combining the mixture with a neutralizing agent in an amount sufficient to neutralize the sulfuric acid ester, and (c) optionally adding water to yield a useful cleaning product. | 2011-04-21 |
20110092407 | LIGHT DUTY LIQUID CLEANING COMPOSITIONS AND METHODS OF MANUFACTURE AND USE THEREOF - The invention encompasses liquid cleaning compositions, for example, dish washing liquids, and methods of their manufacture and use, which possess enhanced cleaning ability. The cleaning compositions of the invention include acidic light duty liquid cleaning compositions with low toxicity and antibacterial efficacy on surfaces, for example, hard surfaces. | 2011-04-21 |
20110092408 | Subtilase Variants - The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. | 2011-04-21 |
20110092409 | VARIANTS OF A FAMILY 44 XYLOGLUCANASE - The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide. | 2011-04-21 |
20110092410 | FLUOROALKYL PHOSPHATE COMPOSITIONS - Fluoroalkyl phosphates containing a tertiary carbon and a nonfluorinated chain are provided. The fluoroalkyl phosphates are useful as surfactants and additives for coating compositions and as treatment agents to impart various surface properties to substrates. | 2011-04-21 |
20110092411 | RECOMBINANT LACTOFERRINS, METHODS OF PRODUCTION FROM PLANTS AND USES THEREOF - The invention concerns the use of a recombinant nucleotide sequence containing a DNAc coding for a lactoferrin, in particular human lactoferrin, or the derived proteins, and elements enabling a plant cell to produce lactoferrin or the derived proteins, coded by said DNAc, in particular a transcription promoter and terminator identified by the plant cell transcription machinery, to transform plant cells in order to obtain, from these cells, or plants obtained therefrom, lactoferrin or derived proteins. | 2011-04-21 |
20110092412 | METHOD OF PRODUCING TAT-HOXB4H - The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation. | 2011-04-21 |
20110092413 | Albumin-Fused Kunitz Domain Peptides - The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer. | 2011-04-21 |
20110092414 | COMPOSITION FOR TREATING VIRUS INFECTION DISEASE COMPRISING JAB1 - Disclosed is a composition for treating or preventing a viral infection or associated disease comprising a Jab1 protein, a nucleic acid having a nucleotide sequence coding for a Jab1 protein or a recombinant virus expressing a Jab1 protein. | 2011-04-21 |
20110092415 | Anti-Viral Compounds - Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection. | 2011-04-21 |
20110092416 | Vitamine B12 - Peptide Conjugates for Oral Delivery - Compositions containing a therapeutic peptide covalently linked to Vitamin B | 2011-04-21 |
20110092417 | LEPTIN FUSION PROTEINS - The disclosure relates to leptin fusion polypeptides; nucleic acid molecules encoding said polypeptides and methods of treatment that use said polypeptides. | 2011-04-21 |
20110092418 | Chimeric Relaxin Polypeptides Comprising an A and B Chain Derived From Different Relaxin Family Peptides - Provided herein are modified relaxin polypeptides wherein the B chain comprises the core amino acid sequence CGR-XXX-R-XX-I/V-XX-CG (SEQ ID NO:1), where X is any amino acid. Also provided are modified relaxin polypeptides comprising at least an A and a B chain, wherein the A and B chains are derived from different naturally occurring relaxins and wherein the B chain comprises the core amino acid sequence CGR-XXX-R-XX-I/V-XX-CG (SEQ ID NO:1), where X is any amino acid. | 2011-04-21 |
20110092419 | PROTEASE-STABILIZED INSULIN ANALOGUES - The present invention relates to novel insulin analogues comprising mutations at position A14 in the A chain and at positions B27, B28, B29 and B30 in the B chain and exhibiting resistance towards protease; a method for the preparation of such insulin analogues; insulin preparations containing the insulin analogues of the invention; and, a method of treating diabetes mellitus using these insulin analogues. | 2011-04-21 |
20110092420 | SELENIUM CONTAINING MODIFYING AGENTS AND CONJUGATES - The invention relates to a modifying agent comprising a water soluble polymer, wherein the water soluble polymer comprises at least one reactive selenium group, said reactive selenium group being capable of reacting with a thiol group thereby forming an —Se—S— bond. Furthermore, the invention relates to a method for producing said modifying agents and their use in the modification of pharmaceutically active agents, e.g. G-CSF. Additionally, the invention concerns conjugates comprising a water-soluble polymer and a pharmaceutically active agent, wherein the water-soluble polymer is linked via a S—Se-bond to agent and a method for their production and their use as medicaments. Finally, the invention concerns a pharmaceutical composition comprising the inventive conjugates. | 2011-04-21 |
20110092421 | METHODS FOR GENERATING NEW HAIR FOLLICLES, TREATING BALDNESS, AND HAIR REMOVAL - The present invention provides methods of treating baldness in a subject and generating new hair follicles, comprising epidermal disruption and administration of a compound that promotes a differentiation of an uncommitted epidermal cell into a hair follicle cell. The present invention also provides methods for hair removal and inducing hair pigmentation. | 2011-04-21 |
20110092422 | ELASTIN BASED GROWTH FACTOR DELIVERY PLATFORM FOR WOUND HEALING AND REGENERATION - The invention is based on the discovery of a potent growth factor delivery system by creating a fusion polypeptide that includes two portions: (i) keratinocyte growth factor protein, and (ii) an elastin-like peptide. This chimera can be administered directly to a wound site, accelerating recovery. | 2011-04-21 |
20110092423 | INHIBITORS OF Akt ACTIVITY - Invented are novel hetero-pyrrole compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis. | 2011-04-21 |
20110092424 | PRODUCTION OF GLUCAGON LIKE PEPTIDE 2 AND ANALOGS - GLP-2 peptides and analogs thereof are produced in high yield and with desired, authentic termini by isolation from a GLP-2 peptide multimer in which at least two units of GLP-2 peptide are coupled through a linker that presents an N-terminal acid cleavage site and a C-terminal enzyme cleavage site. In a specific embodiment, [Gly | 2011-04-21 |
20110092425 | METHOD OF DRUG DELIVERY FOR BONE ANABOLIC PROTEIN - The present invention provides a storage-stable composition containing a parathyroid hormone-related protein (PTHrP) and methods of using a PTHrP and the PTHrP compositions described herein to treat osteoporosis, to increase bone mass or to increase bone quality. The composition is storage stable, in sterile form, and in general may be stored at room temperature for at least several weeks to allow convenient parenteral administration to human patients. | 2011-04-21 |
20110092426 | ORAL CALCITONIN COMPOSITIONS AND APPLICATIONS THEREOF - The present invention relates to compositions for the oral delivery of pharmacologically active calcitonin, to methods of synergistically enhancing the biological effects of orally administered calcitonin with D type vitamins and calcium, and to methods of treating and/or preventing disease in mammals, particularly humans, by orally administering calcitonin compositions in accordance with the invention. | 2011-04-21 |
20110092427 | POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING THE POLYPEPTIDE - Disclosed is a novel polypeptide which can inhibit angiogenesis. Also disclosed is use of the polypeptide. The polypeptide comprises at least one amino acid sequence selected from the amino acid sequences depicted in SEQ ID NOs: 1-3, is composed of 120 or less amino acid residues, and has an anti-angiogenic activity. The polypeptide has an anti-angiogenic activity, has a lower molecular weight compared with that of PEDF, and has excellent penetration or absorption into a living body, particularly an affected part in a living body. | 2011-04-21 |
20110092428 | DETECTING AND CONTROLLING ABNORMAL HEMATOPOIESIS - A method of detecting abnormal hematopoiesis in a subject based on abnormal expression of ZFP36L2, a method of controlling hematopoiesis in a subject altering the level or activity of ZFP36L2 protein in the subject, a method of screening for compounds that modulate hematopoiesis based on changes to ZFP36L2 expression, and compounds identified thereby. | 2011-04-21 |
20110092429 | COMPOSITIONS AND METHODS FOR PRODUCING GAMMA-CARBOXYLATED PROTEINS - The present invention relates to methods and tools for producing large quantities of gamma-carboxylated protein comprising: (i) culturing a cell adapted to express a protein which requires gamma-carboxylation and γ-glutamyl carboxylase in a ratio of at least 10:1, under conditions suitable for expression of both proteins, and (ii) isolating gamma-carboxylated protein. | 2011-04-21 |
20110092430 | METHOD AND COMPOUND FOR THE TREATMENT OF VALVULAR DISEASE - The present invention provides methods for preventing or treating a valvular stenosis or a valvular calcification in a subject, comprising administering to a subject in need thereof a therapeutically effective amount of a peptide/phospholipid complex, wherein the peptide of the complex is an Apolipoprotein A-1 mimetic peptide. In one embodiment the Apolipoprotein A-1 mimetic peptide has the sequence set forth in SEQ ID NO: 1. In another embodiment the phospholipid of the complex is egg sphingomyelin and 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine. | 2011-04-21 |
20110092431 | SKIN AGING-INHIBITING PEPTIDE - The present invention provides a peptide and a composition which are suitable for oral ingestion, and which have a skin aging-inhibiting activity, a collagen-production promoting activity, an epidermal turnover promoting activity, and a cutaneous cell-proliferating effect. The present invention also provides a medicament and a functional food which have a skin aging-inhibiting activity, a collagen-production promoting activity, and a cutaneous cell-proliferation promoting activity. The present invention provides a composition including at least one peptide of Asn-Ile-Pro-Pro-Leu, Ile-Pro-Pro-Leu, Ile-Pro-Pro, Pro-Val-Val-Val-Pro-Pro, Val-Pro-Pro-Phe, Val-Pro-Pro, Phe-Pro-Pro-Gln, and Leu-Pro-Pro-Thr. | 2011-04-21 |
20110092432 | VASCULAR AGING INHIBITOR AND ANTI-AGING FORMULATION - A vascular aging inhibitor includes a low molecular weight collagen derived from fish skin as an essential component, wherein the weight average molecular weight of the low molecular weight collagen derived from fish skin is approximately 3,000. | 2011-04-21 |
20110092433 | FGF9-RELATED METHODS FOR TREATING ANXIETY - The present application relates to the treatment of anxiety in a subject. The invention provides novel diagnostic markers and assays, as well as agents and compounds useful for treating patients who suffer from mental illnesses and anxiety disorders. | 2011-04-21 |
20110092434 | MIMOTOPES OF ALPHA-SYNUCLEIN AND VACCINES THEREOF FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS - The present invention relates to the use of at least one compound comprising the amino acid sequence: (X | 2011-04-21 |
20110092435 | TREATMENT OF PARKINSON'S DISEASE - Described herein are compositions and methods for the treatment of Parkinson's disease (PD) and/or to protect dopaminergic nigrostriatal neuronal cell bodies from 6-OHDA-induced neurotoxicity in a mammal. In various embodiments of the invention, the dopaminergic neuron differentiation factor sonic hedgehog (Shh) and/or its downstream transcription factor target Gli-1 are used in connection with gene therapeutic techniques or direct peptide injection for the aforementioned indications. Kits useful in practicing the inventive method are also disclosed, as are animal models useful for studying various neurodegenerative conditions. | 2011-04-21 |
20110092436 | COMPOUNDS FOR TREATING SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE - The present invention relates to a compound comprising a peptide for treating, preventing and/or ameliorating motor symptoms of Parkinson's disease, said peptide having a binding capacity to an antibody which is specific for an epitope of the amyloid-beta-peptide (Aβ). | 2011-04-21 |
20110092437 | USE OF CYCLIC DEPSIPEPTIDES TO INHIBIT KALLIKREIN 7 - The present application relate to cyclic depsipeptides, or derivatives thereof, having the formula (I), and uses thereof, e.g. as inhibitors of kallikrein 7. | 2011-04-21 |
20110092438 | Composition for external application comprising transcription factor decoy as active ingredient - The present invention provides an external preparation composition of transcription factor decoy of good skin permeability, the composition comprising a transcription factor decoy dissolved in a fatty acid-based ionic liquid obtained from a fatty acid having 2 to 20 carbon atoms and an organic amine compound having 4 to 12 carbon atoms. | 2011-04-21 |
20110092439 | METHOD OF PROMOTING WOUND HEALING - The present disclosure relates to methods of administering relaxin to promote wound healing and reduce scar formation. The disclosure further contemplates the use of relaxin in reconstructive and plastic surgery. | 2011-04-21 |
20110092440 | METHOD OF REGULATING CELL GROWTH USING A PROTEASOME INHIBITOR - This invention provides methods and pharmaceutical compositions for regulating cell growth or inducing apoptosis in a cell, particularly a mammalian tumor cell. Specifically, the invention provides methods for inducing apoptosis in a tumor cell comprising contacting the tumor cell with a proteasome inhibitor and a thiazole antibiotic, particularly each in a suboptimal amount. | 2011-04-21 |
20110092441 | CELL-PERMEABLE ENDOSTATIN RECOMBINANT PROTEIN, A POLYNUCLEOTIDE ENCODING THE SAME, AND AN ANTI-CANCER PREPARATION CONTAINING THE SAME AS AN ACTIVE COMPONENT - The present invention relates to a cell-permeable endostatin recombinant protein in which a macromolecule transduction domain (MTD) is fused to an angiogenesis inhibitor (angiogenesis inhibitor) endostatin; a polynucleotide encoding the cell-permeable endostatin recombinant protein; an expression vector for the cell-permeable endostatin recombinant protein; and a pharmacological composition for an anti-cancer preparation with improved inhibitory activity against angiogenesis in cancer, which contains the cell-permeable endostatin recombinant protein as an active component. The cell-permeable endostatin recombinant protein according to the present invention can block the formation of microvessels and inhibit the migration, proliferation, penetration, tube formation and the like of vascular endothelial cells present in tumor tissue by introducing the angiogenesis inhibitor endostatin into the cell with high efficiency, and it exhibits outstanding anti-cancer activity and so can be used as an anti-cancer drug against various cancers. | 2011-04-21 |
20110092442 | Anticancer agent containing bl-angiostatin - An anticancer agent containing BL-angiostatin as an active ingredient; and a process for producing the same. Also a method for treating cancer comprising administering to a mammal a pharmaceutically effective amount of BL-angiostatin. | 2011-04-21 |
20110092443 | CYCLOSPORINE COMPOSITIONS FOR ENHANCING NAIL GROWTH - The present invention is directed to cyclosporine compositions and methods for stimulating the growth of nails and cuticles in a mammal, including humans. The compositions may be administered topically to the nail bed, nail matrix and cuticle in an amount effective to increase nail growth and thicken, strengthen and smooth the nail. The composition is also effective in strengthening and growing nails, including fingernails and toenails. | 2011-04-21 |
20110092444 | LARGE SCALE PREPARATION OF ALPHA-1 PROTEINASE INHIBITOR AND USE THEREOF - A pharmaceutical preparation containing a purified, active API in the form of a ready to use sterile solution that optionally includes an excipient, diluent or a carrier. At least 90% to 95% of the API is active and is present at a concentration between about 1% to about 10%. The pH of the preparation is in the range of 6.5-7.5 and the preparation is preferably devoid of a protein stabilizer. The API is stable for at least 3 months when stored at a temperature of between 20° C. to 25° C. and is stable for a minimum of at least 12 months, at least 21 months, or at least 36 months when the pharmaceutical composition is stored at a temperature of between 2° C. to 8° C. The composition is formulated to be administered intravenously or by inhalation. | 2011-04-21 |
20110092445 | Amyloid peptide analogues, oligomers thereof, processes for preparing and composi-tions comprising said analogues or oligomers, and their uses - The present invention relates to an amyloid β peptide analogues comprising an amino acid sequence or a peptidomimetic thereof, wherein the sequence (i) forms a loop, (ii) has at least 66% identity to the amino acid sequence of native Aβ peptide or a portion thereof, (iii) comprises at least 6 contiguous amino acid residues and (iv) has at least 2 non-contiguous amino acid residues which are covalently linked with each other, oligomers comprising a plurality of said amyloid β peptide analogues, processes for preparing the amyloid β peptide analogues or oligomers, compositions comprising the amyloid β peptide analogues or oligomers, and uses of the amyloid β peptide analogues or oligomers such as their use for treating or preventing an amyloidosis (e.g. by active immunization), for diagnosing an amyloidosis, and for providing agents that are capable of binding to the amyloid β peptide analogues or oligomers. The subject invention also describes agents that are capable of binding to the amyloid β peptide analogues or oligomers, e.g. antibodies, compositions comprising the agents, and uses of the agents such as their use for treating or preventing an amyloidosis (e.g. by passive immunization) and for diagnosing an amyloidosis. | 2011-04-21 |
20110092446 | COMPOSITIONS AND METHODS FOR TREATMENT OF TRAUMA - The present invention features the use of a complement inhibitor, e.g., a compstatin analog for treating an individual who has suffered a severe injury. In some embodiments, the complement inhibitor may be administered within 24 hours following the injury and optionally also at later time points. The complement inhibitor may, for example, be administered prior to transporting the patient to a health care facility, during transport of the patient to a health care facility, or in the emergency department. Further provided are methods of selecting individuals for such therapy. Further provided are methods of identifying individuals at increased risk of poor outcome following trauma. In certain embodiments the methods comprise determining whether the genotype of the patient includes an allele of a polymorphism in or near a complement-related gene, wherein said allele is associated with risk of poor outcome following trauma. | 2011-04-21 |
20110092447 | USING INHIBITORS OF HISTONE DEACETYLASES FOR THE SUPPRESSION THERAPY OF INHERITED DISEASE PREDISPOSING CONDITIONS - Compounds can be used to act as inhibitors of enzymes having histone deacetylase activity for the medical therapy of conditions which predispose a person for the development of a disease, such as but not limited to cancer, inflammatory or metabolic diseases. Such conditions are linked to genetically inherited mutations of crucial genes which predispose a person with this condition to develop the disease phenotype. Thus, such compounds can be used for a suppressive therapeutic approach—the SUPPRESSION THERAPY—in order to inhibit or delay the onset or progression of the genetically predisposed disorder. Furthermore, a clinically used medicament can be manufactured for the SUPPRESSION THERAPY of such inherited predisposing conditions. | 2011-04-21 |
20110092448 | Peptide Conjugate for Oral Delivery of Hydrophilic Peptide Analgesics - The present invention provides a method of improving the oral delivery of a parent peptide, comprising the step of linking the parent peptide to an added peptide to form a conjugate which has greater oral bioavailability than the parent molecule alone, the added peptide comprising a balance of hydrophobic and hydrophilic residues as defined herein. Conjugates for use in the method are also provided, as are pharmaceutical compositions comprising the conjugate and methods of treatment using the conjugate or pharmaceutical composition. | 2011-04-21 |
20110092449 | TREATMENT OF FIBROTIC CONDITIONS - Compositions, articles, devices and methods for the treatment of fibrosis and fibrotic diseases, disorders, and conditions in humans and non-human animals. | 2011-04-21 |
20110092450 | METHOD OF ENHANCING THE MOBILIZATION OF HEMATOPOIETIC STEM CELLS USING TAT-HOXB4H - The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation. | 2011-04-21 |
20110092451 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE - The present invention comprises compounds useful as antiviral or antitumor agents. The compounds comprise nucleotide analogues that comprise tetrahydrofuranyl or tetrahydrothienyl moeities with quaternary centers at the 3′ position. The nucleotide analogues can be used to inhibit cancer or viruses. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting diseases or conditions associated with cancers and viruses. Thus, the present invention also comprising pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit viruses or tumors and treat, prevent, or inhibit the foregoing diseases. | 2011-04-21 |
20110092452 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING PANCREATIC CANCER - The present invention provides compositions and methods for treating and diagnosing the presence of solid tumor stem cells in a patient (e.g., based on the presence of c-Met). In certain embodiments, the presence or absence of solid tumor stem cells (e.g., pancreatic solid tumor stem cells) can be determined through the use of a single cells surface marker (e.g., c-Met). The present invention also provides methods for screening candidate compounds (e.g., c-Met antagonists) for the ability to inhibit the tumorigenisis of pancreatic solid tumor stem cells. | 2011-04-21 |