16th week of 2014 patent applcation highlights part 56 |
Patent application number | Title | Published |
20140107319 | CARRIER FOR SEPARATION, METHOD FOR SEPARATION OF COMPOUND, AND METHOD FOR SYNTHESIS OF PEPTIDE USING THE CARRIER - Disclosed are a carrier for use for separation purpose and a method for separation of a compound which enable a chemical reaction to be performed in a liquid phase, enable a compound of interest to be separated from the liquid phase after the completion of the reaction readily, enable the separated compound to be evaluated by structural analysis or the like while the compound being bound to the carrier, and enable the compound to be separated from the carrier readily. A carrier for separation which has a reaction site capable of reacting with other compound on a benzene ring, and a long-chain group having a specified carbon atom(s) at each of the ortho-position and the para-position of the reaction site through an oxygen atom. | 2014-04-17 |
20140107320 | BLOOD COAGULATION PROTEIN CONJUGATES - The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a blood coagulation protein comprising contacting the oxidized carbohydrate moiety with an activated water soluble polymer under conditions that allow conjugation. More specifically, the present invention relates to the aforementioned materials and methods wherein the water soluble polymer contains an active aminooxy group and wherein an oxime linkage is formed between the oxidized carbohydrate moiety and the active aminooxy group on the water soluble polymer. In one embodiment of the invention the conjugation is carried out in the presence of the nucleophilic catalyst aniline. In addition the generated oxime linkage can be stabilized by reduction with NaCNBH | 2014-04-17 |
20140107321 | PURIFICATION OF ANTIBODIES - The invention provides a method of purification of antibodies using chromatographic technique. The method involves the use of cation-exchange chromatography for the purification of the antibody. The purified antibody can be used as a therapeutic composition. | 2014-04-17 |
20140107322 | METHODS OF USE OF SOLUBLE CD24 FOR THERAPY OF RHEUMATOID ARTHRITIS - Provided herein is a CD24 protein. The CD24 protein may include mature human or mouse CD24, as well as a N- or C-terminally fused portion of a mammalian immunoglobulin. | 2014-04-17 |
20140107323 | SDP-containing Heterobifunctional Agents - The present disclosure is directed to a reactive ester agent for conjugating a click-reactive group to a carrier molecule or solid support. The reactive ester agent has the general formula IA, wherein the variables R | 2014-04-17 |
20140107324 | Growth Hormones with Prolonged In-Vivo Efficacy - The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. Further described are methods of preparing and using such compounds. These growth hormone compounds are based on there althered profile considered particular useful in therapy. | 2014-04-17 |
20140107325 | PREPARATION OF HIGH-PURITY GADOBUTROL - What is described is a process for producing high-purity gadobutrol in a purity (according to HPLC) of more than 99.7 or 99.8 or 99.9% and the use for preparing a pharmaceutical formulation for parenteral administration. The process is carried out using specifically controlled crystallization conditions. The more recent developments in the field of the gadolinium-containing MR contrast agents (EP 0448191 B1, CA Patent 1341176, EP 0643705 B1, EP 0986548 B1, EP 0596586 B1) include the MRT contrast agent gadobutrol (Gadovist® 1.0) which has been approved for a relatively long time in Europe and more recently also in the USA under the name Gadavist®. | 2014-04-17 |
20140107326 | METHODS INVOLVING GRAPHENE AND FUNCTIONALIZED GRAPHENE - Embodiments relating to the synthesis and processing of graphene molecules are provided. In some cases, methods for the electrochemical expansion and/or functionalization of graphene molecules are provided. In some embodiments, one or more species may be intercalated between adjacent graphene sheets. | 2014-04-17 |
20140107327 | METHODS FOR PREPARING DEUTERATED 1,2,3-TRIAZOLES - This disclosure relates to a method that involves reacting an azide with an alkyne in the presence of deuterated water and a copper-containing catalyst, thereby forming a deuterated 1,2,3-triazole. | 2014-04-17 |
20140107328 | CHEMOSELECTIVE ENRICHMENT FOR COMPOUND ISOLATION - Chemoselective isolation of aliphatic hydroxyl group-containing and aromatic hydroxyl group-containing compounds is accomplished via formation of polymeric siloxyl ethers. Chemoselective release of aliphatic hydroxyl group-containing and aromatic hydroxyl group-containing compounds from polymeric siloxyl reagents is described. | 2014-04-17 |
20140107329 | N,N,N-TRILAKYLAMINOPOLYMERS, METHODS OF THEIR PREPARATION AND USES THEREOF - There is provided a method for the preparation of an N,N,N-trialkylaminopolymer having one or more unsubstituted heteroatoms different from nitrogen atom. The method comprises a first step of alkylating an aminopolymer to produce an N,N-dialkylaminopolymer, wherein substantially no N,N,N-trialkylaminopolymer is produced; and a second step of alkylating the N,N-diaminopolymer to produce the N,N,N-trialkylaminopolymer. The N,N,N-trialkylaminopolymer is produced with a satisfactory degree of quaternization and with only a low percentage of the unsubstituted heteroatoms alkylated. The N,N,N-trialkylaminopolymer can be an N,N,N-trialkylaminopolysaccharide or an N,N,N-trialkylchitosan such as N,N,N-trimethylchitosan. | 2014-04-17 |
20140107330 | OLIGOMERIC COMPOUNDS COMPRISING BICYCLIC NUCLEOTIDES AND USES THEREOF - The present invention provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount activity or expression of the target nucleic acid in a cell. | 2014-04-17 |
20140107331 | PHOTORESPONSIVE NUCLEIC ACID MANUFACTURING METHOD - The present invention provides a manufacturing method that can easily manufacture a compound known as photoresponsive (photocoupling) nucleic acids at high yield in a shorter period of time than that of the conventional technology. The present invention relates to a method of manufacturing a photoresponsive nucleic acid which includes a step of reacting a nucleic acid having groups represented by the Formula I, the Formula III, the Formula IV, or the Formula V and a compound represented by the Formula II, or reacting a nucleic acid having groups represented by the Formula VI, the Formula VIII, the Formula IX, or the Formula X and a compound represented by the Formula VII by heating them by microwaves in the presence of a metal catalyst, a basic substance, and a solvent. | 2014-04-17 |
20140107332 | SERIES OF DRUGS USING PHOTOFRIN TO CATALYZE DECOMPOSITION OF HYDROGEN PEROXIDE - The present invention relates to a series of new drugs which refer to chemical series capable of catalyzing the decomposition of H | 2014-04-17 |
20140107333 | POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING - Embodiments of the present disclosure provide compositions including metal-organic polyhedrons, metalloporphyrin framework structures, methods of making these, methods of using these, and the like. | 2014-04-17 |
20140107334 | PROCESS FOR THE SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of the compound of formula (I): | 2014-04-17 |
20140107335 | Cyclic Amines - The present invention is directed to novel cyclic amines which inhibit the P2X | 2014-04-17 |
20140107336 | TRI-ARYL COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME - The present invention relates to a novel class of tri-aryl compounds, compositions comprising the same and processes for the preparation thereof. | 2014-04-17 |
20140107337 | PROCESS FOR FOSAPREPITANT - The present invention provides a novel process for reducing palladium content in fosaprepitant dimeglumine. | 2014-04-17 |
20140107338 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME - The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device using the same. Said organic luminescent compound provides an organic electroluminescent device which has high luminous efficiency and a long operation lifetime and requires a low driving voltage improving power efficiency and power consumption. | 2014-04-17 |
20140107339 | SUBSTITUTED 3-HYDROXY-DELTA-LACTONES FROM EPOXIDES - Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed. | 2014-04-17 |
20140107340 | Benzamides - The present invention is directed to benzamide containing compounds which inhibit the P2X7 receptor | 2014-04-17 |
20140107341 | COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS - The present invention relates to compounds containing hydrido-tricyano-borate anions, their preparation and their use, in particular as part of electrolyte formulations for electrochemical or optoelectronic devices. | 2014-04-17 |
20140107342 | CAMPTOTHECIN DERIVATIVE, AND PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION AND APPLICATION - The present invention relates to a camptothecin derivative having a structure as represented by Formula (II), in which X | 2014-04-17 |
20140107343 | INDENOPYRIDINE DERIVATIVES - Disclosed is a compound of formula (I) | 2014-04-17 |
20140107344 | ZINC SALT OF ISOTHIAZOLONE COMPOUND, METHOD FOR REDUCING IRRITATION CAUSED BY ISOTHIAZOLONE COMPOUND, ANTIBACTERIAL AND ANTIFUNGAL METHOD USING ZINC SALT OF ISOTHIAZOLONE COMPOUND, AND ANTIBACTERIAL AND ANTIFUNGAL COMPOSITION - A method for reducing irritation caused by an isothiazolone compound represented by formula (1) by converting the isothiazolone compound represented by formula (1) into a zinc salt, where R | 2014-04-17 |
20140107345 | Compositions for Oral Administration of Zoledronic Acid or Related Compounds for Treating Disease - Oral dosage forms of bisphosphonate compounds, such as zoledronic acid, can be used to treat or alleviate pain or related conditions. The oral bioavailabilty of zoledronic acid can be enhanced by administering the zoledronic acid in the disodium salt form | 2014-04-17 |
20140107346 | PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS - A process for the preparation of pyrazolopyrolidines of structural formula I: and W is or P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process. | 2014-04-17 |
20140107347 | Method for Producing Pyrazole Compound - A method for producing a pyrazole compound of the general formula (5) includes reacting a 2-acyl-3-aminoacrylic acid ester of the general formula (1) with a hydrazine of the general formula (4) in the presence of a base | 2014-04-17 |
20140107348 | METHODS FOR THE PREPARATION OF ARYL AMIDES - The present invention relates to methods of initiating a reaction represented by scheme 1 | 2014-04-17 |
20140107349 | Methods for Preparing Polymeric Reagents - The present invention provides among other things methods for preparing polymeric reagents, wherein the method comprises (a) providing an aromatic moiety bearing a hydroxy group, a first amino group and a second amino group; (b) reacting a functional group reagent with the hydroxy group to result in a hydroxy group bearing a functional group capable of reacting with an amino group of an active agent and resulting in a hydrolyzable carbamate; and (c) reacting a plurality of poly(alkylene glycol) water-soluble polymers bearing a reactive group with the first amino group and second amino group to result in (i) a first amino group bearing a water-soluble polymer through a spacer moiety, and (ii) a second amino group bearing a second water-soluble polymer through a spacer moiety. | 2014-04-17 |
20140107350 | Process for Preparing Episulfide Compounds - Provided is a method for producing an episulfide compound, the method including a step of thiating epoxy groups of (B) an epoxy compound by a reaction with (C) a thiating agent in the presence of (A) a polyhydric hydroxyl compound having two or more hydroxyl groups. | 2014-04-17 |
20140107351 | Fullerene-Containing Hemicarceplexes and a Method of Purifying Fullerenes by Using the Same - Fullerene⊙CTV complexes, comprising fullerene⊙CTV hemicarceplexes, formed by various cyclotriveratrylene (CTV)-based molecular cages and various fullerene guests are disclosed. A method of direct isolating at least a fullerene from fullerene mixtures by using the above fullerene CTV hemicarceplexes but without using crystallization or HPLC is also disclosed. | 2014-04-17 |
20140107352 | PROCESS FOR THE INTEGRATED PREPARATION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYLTETRAHYDROPYRANS AND OF 2-SUBSTITUTED 4-METHYLTETRAHYDROPYRANS - The present invention relates to a process for the integrated preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans and of 2-substituted 4-methyltetrahydropyrans. | 2014-04-17 |
20140107353 | Reductive Biomass Liquefaction - The present invention provides methods, reactor systems, and catalysts for converting in a continuous process biomass to less complex oxygenated compounds for use in downstream processes to produce biofuels and chemicals. The invention includes methods of converting the components of biomass, such as hemicellulose, cellulose and lignin, to water-soluble materials, including lignocellulosic derivatives, cellulosic derivatives, hemicellulosic derivatives, carbohydrates, starches, polysaccharides, disaccharides, monosaccharides, sugars, sugar alcohols, alditols, polyols, diols, alcohols, ketones, cyclic ethers, esters, carboxylic acids, aldehydes, and mixtures thereof, using hydrogen and a heterogeneous liquefaction catalyst. | 2014-04-17 |
20140107354 | New Methodology for the Synthesis of Xanthones - Methods are provided for forming a xanthone derivative via reacting a 2-substituted benzaldehyde with a phenol derivative to form the xanthone derivative. | 2014-04-17 |
20140107355 | METHOD TO CONVERT MONOSACCHARIDES TO 5-(HYDROXYMETHYL) FURFURAL (HMF) USING BIOMASS-DERIVED SOLVENTS - Described is a process to produce hydroxymethyl furfural (HMF) from biomass-derived sugars. The process includes the steps of reacting a C5 and/or C6 sugar-containing reactant derived from biomass in a monophasic or biphasic reaction solution comprising water and a co-solvent. The co-solvent can be beta-, gamma-, and/or delta-lactones derived from biomass, tetrahydrofuran (THF) derived from biomass, and/or methyltetrahydrofuran (MTHF) derived from biomass. The reaction takes place in the presence of an acid catalyst and a dehydration catalyst for a time and under conditions such that at least a portion of glucose or fructose present in the reactant is converted to HMF. | 2014-04-17 |
20140107356 | METHODS FOR PRODUCING EPOXIDATION CATALYSTS AND EPOXIDATION METHODS UTILIZING THEM - A method for producing epoxidation catalysts is provided. The catalyst comprises a support, a catalytic species, maganese and at least one alkali metal and/or promoter. The catalytic species may be silver. The catalyst is prepared by a method wherein at least a portion of the manganese is impregnated in a step separate from the at least one alkali metal and/or promoter. Advantageously, catalysts produced by the present method may exhibit greater efficiencies than catalysts produced by conventional methods. A method for the epoxidation of alkylenes using the catalysts so produced is provided as is a method for using the alkylene oxides for the production of 1,2-diols, 1,2-carbonates, 1,2-diol ethers, or alka-nolamines. | 2014-04-17 |
20140107357 | TIGECYCLINE CRYSTALLINE HYDRATE AND PREPARATION METHOD THEREFOR AND USE THEREOF - Provided are a Tigecycline crystalline hydrate, and a preparation method therefor and use thereof. The crystalline hydrate has high stability for storage, and is used for the manufacture of a medicament for treating or preventing the infection of respiratory system, hepatobiliary system, facial features, urogenital system, bone and joint, skin and soft tissue and endocarditis, septicemia, meningitis caused by susceptible strains of Gram-positive or Gram-negative bacteria, anaerobic bacteria, chlamydia, and mycoplasma in human or animal. | 2014-04-17 |
20140107358 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES - The present invention relates to a process for the preparation of a compound of formula (I) said process comprising the steps of: a) reacting a compound of formula (II), with an acylating or a silylating agent to produce a compound of formula (III), wherein P | 2014-04-17 |
20140107359 | Heated Chromatographic Separation Process - The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises passing the feed mixture through one or more chromatographic columns containing, as eluent, an aqueous organic solvent, wherein the temperature of at least one of the chromatographic columns through which the feed mixture is passed is greater than room temperature. | 2014-04-17 |
20140107360 | LIPID-LOWERING ANTIDIABETIC AGENT - A composition which includes a salt of metformin and the use of the composition for treatment of or use in prediabetes, diabetes, lowering triglycerides and/or other conditions in mammals. | 2014-04-17 |
20140107361 | MODIFYING THE FATTY ACID PROFILE OF CAMELINA SATIVA OIL - The present disclosure provides methods and compositions for modifying fatty acids in | 2014-04-17 |
20140107362 | HEXAFLUORODIMETHYLCARBINOL TERMINATED ALKANE- AND ALKENETHIOLS - A hexafluorodimethylcarbinol terminated compound, method of making it, and a composition of matter are disclosed. The compound may have the formula (CF | 2014-04-17 |
20140107363 | Stereoselective Synthesis of Bridged Metallocene Complexes - The present invention provides methods of making stereo-enriched ansa-metallocene compounds using an unchelated amine compound. Generally, these methods result in a rac:meso isomer selectivity of the stereo-enriched ansa-metallocene compound of greater than 4:1. | 2014-04-17 |
20140107364 | Organic Electronic Device and Dopant for Doping an Organic Semiconducting Matrix Material - An organic electronic device includes a substrate, a first electrode arranged on the substrate, at least a first functional organic layer arranged on the first electrode and a second electrode arranged on the first functional organic layer. The first functional organic layer includes a matrix material and a p-dopant with regard to the matrix material, wherein the p-dopant includes a copper complex containing at least one ligand. | 2014-04-17 |
20140107365 | MULTI-THIOL MERCAPTOALKOXYSILANE COMPOSITIONS - The present invention provides multi-thiol mercaptoalkoxysilane compositions and methods of making multi-thiol mercaptoalkoxysilane compositions having the formula: | 2014-04-17 |
20140107366 | Hydrosilylation Synthesis of Haloalkylorganosilanes Using Peroxide Promoters - This invention is directed to a process for producing a haloorganoalkoxysilane product comprising reacting an olefinic halide, an alkoxysilane, a catalytically effective amount of ruthenium-containing catalyst; and a reaction-promoting effective amount of a peroxy compound, optionally in the presence of an electron-deficient aromatic compound. | 2014-04-17 |
20140107367 | METHOD FOR PRODUCING 2-CHLOROALLYL THIOCYANATE AND 2-CHLOROALLYL ISOTHIOCYANATE - A process is described for producing 2-chloroallyl isothiocyanate from 2,3-dichloro-1-propene by reacting the 2,3-dichloro-1-propene with a thiocyanate in the presence of a phase transfer catalyst, without diluent or in the presence of up to 15 percent by weight based on 2,3-dichloropropene and simultaneously in the presence of an excess of from 10 to 200 mol percent of 2,3-dichloro-1-propene based on the thiocyanate. A process starting from 1,2,3-trichloropropane is also described. | 2014-04-17 |
20140107368 | AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD - A pest control agent containing a compound represented by the following Formula (1), wherein A represents a carbon atom, a nitrogen atom, or the like, K represents a non-metal atom group necessary for forming a cyclic linking group derived from a 5- or 6-membered aromatic ring, in combination with A and two carbon atoms to which A bonds, X represents a hydrogen atom, a halogen atom, or the like, n represents an integer of from 0 to 4, T represents —C(=G | 2014-04-17 |
20140107369 | COMPOUNDS USEFUL IN THE SYNTHESIS OF BENZAMIDE COMPOUNDS - Compounds that are useful in the synthesis of 2-amino-4,6-dimethoxybenzamide derivatives and other benzamide compounds. | 2014-04-17 |
20140107370 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS - The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): | 2014-04-17 |
20140107371 | CATALYSIS BY METAL NANOPARTICLES DISPERSED WITHIN A HIERARCHICALLY POROUS CARBON MATERIAL - Disclosed are hierarchically porous carbon materials with a plurality of discreet nanoparticles dispersed on their carbon phase. The materials possess a continuous network of pores that spans the porous material, permitting the flow of fluids into and through the material. The porous materials can be used as heterogeneous catalysts. | 2014-04-17 |
20140107372 | METHOD FOR PRODUCING CYCLOPENTANONE COMPOUND, AND INTERMEDIATE COMPOUND - In order to provide a novel method for producing a cyclopentanone compound, the present invention is a method for producing a cyclopentanone compound represented by the formula (I). The method includes the steps of: substituting the group represented by Y by a hydrogen atom by allowing a compound represented by the formula (III) or an intermediate compound obtained from the compound represented by the formula (III) to react with a catalyst or a halogenating agent; and substituting, by hydrogen atoms, (i) the group or the atom represented by Z | 2014-04-17 |
20140107373 | Polyvalent Vinyl Aromatic Compound and Method for Producing Same - A polyvalent vinyl aromatic compound represented by chemical formula (4) is produced by reacting (1) a specific vinyl aromatic compound and (2) a specific vinyl compound in the presence of (3-1) a metal complex and (3-2) a percarboxylic acid or a hypervalent iodine compound so that a vinyl group derived from the vinyl compound is introduced onto a carbon atom that is adjacent to the carbon atom to which a vinyl group is bonded in the vinyl aromatic compound. (In the formula, Ar represents a monocyclic aromatic hydrocarbon group or the like; R | 2014-04-17 |
20140107374 | FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME - The presently disclosed and claimed inventive concept(s) relates generally to the functionalized polyethylene terephthalate polymers and functionalized derivatives of PET. More particularly, but not to be construed as limiting, the presently disclosed and claimed inventive concept(s) relate to lower molecular weight functionalized digested PET materials from digesting recycled and methods of making and using same. | 2014-04-17 |
20140107375 | PROCESS FOR OXIDIZING IMPURITIES IN CRUDE TEREPHTHALIC ACID - A process for oxidizing solid crude terephthalic acid is described. The process includes contacting solid crude terephthalic acid with a solvent comprising a carboxylic acid and one or more of an ionic liquid or ammonium acetate; a bromine source; a catalyst; and an oxidizing agent to produce solid purified terephthalic acid at a temperature of about 100 to about 210° C., and a pressure of about 2 to about 4.5 MPa, for a time of about 5 to about 60 min, and recovering the solid purified terephthalic acid. | 2014-04-17 |
20140107376 | DENDRIMERS AND METHODS FOR THEIR PREPARATION - Provided are new dendrimers and processes for making them. The dendrimers are derived from a nitroalkyloxirane compound of formula (III): wherein R | 2014-04-17 |
20140107377 | Microorganisms And Methods For Producing Acrylate And Other Products From Propionyl-CoA - This invention relates to microorganisms that convert a carbon source to acrylate or other desirable products using propionyl-CoA as an intermediate. The invention provides genetically engineered microorganisms that carry out the conversion, as well as methods for producing acrylate by culturing the microorganisms. Also provided are microorganisms and methods for converting propionyl-CoA and propionate to 3-hydroxypropionyl-CoA, 3-hydroxypropionate (3-HP) and poly-3-hydroxypropionate. | 2014-04-17 |
20140107378 | PROCESS FOR OBTAINING PURE ANILINE - A process for obtaining pure aniline contains
| 2014-04-17 |
20140107379 | PROCESS FOR PREPARING ISOPHORONE IN THE PRESENCE OF AT LEAST ONE DEFOAMER IN THE WASTEWATER COLUMN IN THE WORKUP SECTION - The invention relates to a process for preparing isophorone (3,5,5-trimethyl-2-cyclohexen-1-one) in the presence of at least one defoamer in the wastewater column in the workup section. | 2014-04-17 |
20140107380 | METHOD FOR PRODUCING BIODERIVED DIPROPYLENE AND TRIPROPYLENE GLYCOLS WITHOUT PROPYLENE OXIDE - A method is provided for producing bioderived dipropylene and tripropylene glycols without using propylene oxide. The method utilizes a bioderived (mono)propylene glycol as a feed, and in one embodiment performs an acid-catalyzed condensation process to convert the bioderived propylene glycol to products including at least dipropylene glycol and preferably including tripropylene glycol as well. Wholly biobased dipropylene glycol and tripropylene glycol products and derivative products made therefrom are described, with compositions of matter including the wholly biobased dipropylene glycol and tripropylene glycol or a derivative thereof and describing uses of the various wholly biobased products or of the compositions including the wholly biobased products. Biobased polypropylene glycols may be made in the same manner. | 2014-04-17 |
20140107381 | HYDROXIDE CATALYSTS FOR LIGNIN DEPOLYMERIZATION - Solid base catalysts and their use for the base-catalyzed depolymerization (BCD) of lignin to compounds such as aromatics are presented herein. Exemplary catalysts include layered double hydroxides (LDHs) as recyclable, heterogeneous catalysts for BCD of lignin. | 2014-04-17 |
20140107382 | METHODS AND APPARATUSES FOR SEPARATING A LINEAR HEXANE STREAM FROM A HYDROCARBON FEED - Methods of and apparatuses for separating a linear hexane stream from a hydrocarbon feed that includes unbranched C | 2014-04-17 |
20140107383 | Selective Hydrogenation Catalyst and Methods of Making and Using Same - A composition comprising a supported hydrogenation catalyst comprising palladium and an organophosphorous compound, the supported hydrogenation catalyst being capable of selectively hydrogenating highly unsaturated hydrocarbons to unsaturated hydrocarbons. A method of making a selective hydrogenation catalyst comprising contacting a support with a palladium-containing compound to form a palladium supported composition, contacting the palladium supported composition with an organophosphorus compound to form a catalyst precursor, and reducing the catalyst precursor to form the catalyst. A method of selectively hydrogenating highly unsaturated hydrocarbons to an unsaturated hydrocarbon enriched composition comprising contacting a supported catalyst comprising palladium and an organophosphorous compound with a feed comprising highly unsaturated hydrocarbon under conditions suitable for hydrogenating at least a portion of the highly unsaturated hydrocarbon feed to form the unsaturated hydrocarbon enriched composition. | 2014-04-17 |
20140107384 | Method for Providing a Co-Feed in the Coupling of Toluene with a Carbon Source - A process for making styrene is disclosed that includes reacting toluene with a C | 2014-04-17 |
20140107385 | OXIDATIVE COUPLING OF METHANE SYSTEMS AND METHODS - Systems and methods conducive to the formation of one or more alkene hydrocarbons using a methane source and an oxidant in an oxidative coupling of methane (OCM) reaction are provided. One or more vessels each containing one or more catalyst beds containing one or more catalysts each having similar or differing chemical composition or physical form may be used. The one or more catalyst beds may be operated under a variety of conditions. At least a portion of the catalyst beds may be operated under substantially adiabatic conditions. At least a portion of the catalyst beds may be operated under substantially isothermal conditions. | 2014-04-17 |
20140107386 | Polymerization Process - The present invention relates to a polymerization process of producing ethylene-alpha-olefin polymer. The polymerization process comprises supplying at a feed temperature a feed containing ethylene, at least one alpha-olefin and optionally, a diene in a solvent, the solvent is supplied at a solvent feed rate; supplying at a catalyst feed rate a catalyst to a reactor, and contacting the feed with the catalyst to produce a reaction mixture containing the polymer. The present invention also relates to processes for improving the energy utilization of polymerization processes, wherein the process comprises decreasing the feed temperature, decreasing the solvent feed rate, and decreasing the catalyst feed rate. | 2014-04-17 |
20140107387 | PROCESSES FOR PRODUCTION OF ISOBUTENE AND TERTIARY BUTANOL - An object of the present invention is to provide, for the production of isobutene, a high-yielding, highly-selective, and long-term stable production process of isobutene from TBA. With respect to the production of TBA, an object of the present invention is to provide a TBA production process in which, through long-term stable maintenance of a high reaction activity, long-term continuous operation is enabled and the productivity is improved. The present invention discloses a process for producing isobutene that employs a dehydration temperature of from 200 to 450° C. in use of an alumina catalyst that contains a Na content of 0.6% by weight or less in terms of NaO | 2014-04-17 |
20140107388 | FUEL GAS CONDITIONING PROCESS USING GLASSY POLYMER MEMBRANES - Disclosed herein is a process for conditioning natural gas containing C | 2014-04-17 |
20140107389 | METHOD AND COMPOSITION FOR SEQUESTRATION OF ARSENIC - A method for sequestrating arsenic oxides, comprising forming an insoluble and stable glass incorporating a fully oxidized form of arsenic generated by oxidation of an initial lower oxide of arsenic and stabilization by calcium salt formation. The glass composition for sequestration of arsenic comprises from 50 to 75% silica; from 0.5 to 3% Al | 2014-04-17 |
20140107390 | IMPLEMENTATION AND EXPERIMENTAL RESULTS OF REAL-TIME 4D TUMOR TRACKING USING MULTI-LEAF COLLIMATOR (MLC), AND/OR MLC-CARRIAGE (MLC-BANK), AND/OR TREATMENT TABLE (COUCH) - Methods and systems of operating a support structure and beam shaping mechanism in a manner that compensates for motion patterns exhibited by a patient, promotes comfort of the patient, and optimizes accuracy of delivery of radiotherapy to a targeted location within the patient. The support structure can be a treatment table or couch and the beam shaping mechanism can be a multi-leaf collimator (MLC), and/or an MLC-bank/-carriage. The control system can utilize algorithms for predicting tumor motion and loading condition on the table/couch during radiation therapy. | 2014-04-17 |
20140107391 | USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY - The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules or α2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality. | 2014-04-17 |
20140107392 | Method of Dose Comparison for In Vivo Dosimetry - The invention relates to in vivo dosimetry techniques and can be used for comparison of dose measured in reference point and dose calculated at the same place with computerized treatment planning system. The suggested method takes into consideration dose difference and distance-to-agreement between measured and calculated points and uses a region of measurements (ROM) contoured as an organ at risk so that dose differences inside the ROM and acceptance interval are defined with the dose volume histogram of the ROM. The method can be used for evaluation of influence of ROM homogeneity and dosimeter movement on the difference between calculated and measured doses. | 2014-04-17 |
20140107393 | DEVICE FOR RESTRAINT OF PATIENTS ON A TABLE - The present invention is a device for the restraint of patients on a treatment table. More specifically, the invention is designed to provide lateral side pressure on a patient in the abdomen, thorax, and hip areas during a radiation treatment. The main components of the device are paddle(s) and at least one crossbar assembly. The paddles are coupled to a crossbar assembly, which is positioned on a treatment table under the body cushion in which the patient is positioned. The paddles can be moved laterally along the crossbar such that they put lateral pressure on the cushion and the patient. | 2014-04-17 |
20140107394 | SYSTEM AND METHODS FOR USING A DYNAMIC SCHEME FOR RADIOSURGERY - The present invention is a method and system for developing a dynamic scheme for Gamma Knife radiosurgery based on the concept of “dose-painting” to take advantage of robotic patient positioning systems on the Gamma Knife C and Perfexion units. The spherical high dose volume created by the Gamma Knife unit will be viewed as a 3D spherical “paintbrush”, and treatment planning is reduced to finding the best route of this “paintbrush” to “paint” a 3D tumor volume. Under the dose-painting concept, Gamma Knife radiosurgery becomes dynamic, where the patient is moving continuously under the robotic positioning system. | 2014-04-17 |
20140107395 | HADRON TREATMENT PLANNING WITH ADEQUATE BIOLOGICAL WEIGHTING - Treatment planning methods are provided that determine the variability of relative biological effectiveness (RBE) along a beam line and calculate, among other things, what intensity of hadron beam such as a proton or a carbon ion beam should be applied to achieve a desired biological dose at treatment site of a patient afflicted with a medical condition. Typically, three or four RBE values at three or four corresponding spacially-dispersed intervals along the beam line are calculated. In one embodiment, two RBE values for the spread-out Bragg peak (SOBP) region of the treatment site; one for the proximal section and one for the declining distal section is calculated. A third and different RBE value may be determined for the distal edge region of the SOBP. A fourth value may also be calculated for a pre-SOBP region. | 2014-04-17 |
20140107396 | SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT - Devices, systems, and methods for delivering a therapeutic agent to a treatment region in the body are disclosed. By determining a treatment region in the body, reducing the volume of the treatment region to create a target region by using one or more flow control elements and delivering at least one therapeutic agent to the target region, improved treatment may be achieved. | 2014-04-17 |
20140107397 | METHODS AND DEVICES FOR TREATING PRIMARY HEADACHE - Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated. | 2014-04-17 |
20140107398 | METHODS AND DEVICES FOR TREATING PRIMARY HEADACHE - Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated. | 2014-04-17 |
20140107399 | DEVICES, SYSTEMS, AND METHODS FOR FACILITATING FLOW FROM THE HEART TO A BLOOD PUMP - An apparatus includes a tubular member defining a lumen and a channel, and a support member. The tubular member has a connection portion configured to be coupled to an organ wall. An outer edge of the connection portion is configured to contact a first portion of an inner surface of the wall when the connection portion is in an expanded configuration such that an interior volume of the organ is in fluid communication with the lumen. The support member is movably disposed within the channel and is configured to minimize movement of the wall relative to the tubular member. An end portion of the support member is disposed within the channel when the support member is in a first configuration. The end portion of the support member configured to contact a second portion of the inner surface of the wall when the support member is in a second configuration. | 2014-04-17 |
20140107400 | TEMPLATE FOR IMPLANTING A HOUSING OF A HEARING INSTRUMENT - The invention relates to a template for implanting a housing of an implantable unit of a partially implantable hearing instrument, comprising a template plate comprising an implant position marking opening and a template position indicating element which extends substantially normal with regard to the surface of the template plate, wherein the implant position marking opening is designed to mark the position of a receptacle to be created in the patient's temporal bone for receiving an elevated housing positioning portion of the housing, and wherein the template position indicating element is a projection designed to be seen or felt by a surgeon through the patient's skin when the template plate is positioned at the patient's skull to mark the position of said receptacle. | 2014-04-17 |
20140107401 | Digital Sound Relaxation and Sleep-Inducing System and Method - In one embodiment, an improved-customizability digital sound relaxation system having a sound card receiving port and a collectable sound card are cooperative to play prerecorded natural or other sounds by depressing one of a plurality of sound selector switches and a sound card selector switch. The new sounds of each collectable sound card customize the library of available sounds to individual taste. In another embodiment, an improved-flexibility digital sound relaxation system having at least two (2) prerecorded sounds stored at first and second memory locations of internal or external/internal memory devices may be selected and combined for concurrent and/or individual replay by depressing one of a plurality of sound selector switches and a combine switch, or by depressing one of a plurality of sound selector switches, a sound card selector switch and a combine switch. In this manner, from eighteen (18) digitally prerecorded sounds of the preferred embodiment ninety (90) individually selectable and/or combinable sounds are made available. In either embodiment, natural or other sounds may be stored in loop or sound bite format in either or both of the internal and external memories. In a further sound relaxation and sleep-inducing embodiment, first and second preselected sound patterns selected respectively to mask sound and soothe the listener and to induce a state of deep relaxation that helps the listener to fall asleep may be selected by depressing combination mode select and sequential sound selector switches. In alarm mode, sound select and alarm check buttons respectively allow any sound of the library of prerecorded sounds (sound card or internal, single or mixed) to be selected as the alarm wake-up sound and one-touch alarm status display and audible alarm replay of any sound selected at wake-up volume in sound wake-up mode. | 2014-04-17 |
20140107402 | Adjustable Pessary Device and Method - Various embodiments of an adjustable pessary device are provided. The device can include an elastic ribbon or band, such as Nitinol, encapsulated in a soft or flexible structure, such as a rubber shell. In addition to providing a conforming, comfortable shape, the rubber layer can have additional structures to interface and fit with the anatomical structures within the vagina. | 2014-04-17 |
20140107403 | INCONTINENCE TREATMENT DEVICE - An incontinence treatment system includes a urethral support extending between a first end and a second end, a first connector attached to the first end of the urethral support and a second connector attached to the second end of the urethral support, and an energy source. At least one of the first connector and the second connector is a cross-linked polymer connector having a glass transition temperature between 40-70 degrees Celsius. In this regard, the cross-linked polymer connector is stretched to provide a stretched cross-linked polymer connector having a product length. The energy source is adapted to provide energy from an extracorporeal location through intact skin to shorten the stretched cross-linked polymer connector to an implant length that is less than the product length. | 2014-04-17 |
20140107404 | SYSTEMS, METHODS AND DEVICES FOR PERFORMING GYNECOLOGICAL PROCEDURES - Systems, methods, apparatus and devices for performing improved gynecologic and urologic procedures are disclosed. The system and devices provide simplified use and reduced risk of adverse events. Patient benefit is achieved through improved outcomes, reduced pain, especially peri-procedural pain, and reduced recovery times. The various embodiments enable procedures to be performed outside the hospital setting, such as in a doctor's office or clinic. | 2014-04-17 |
20140107405 | CARDIAC TREATMENT SYSTEM AND METHOD - Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. | 2014-04-17 |
20140107406 | CARDIAC TREATMENT SYSTEM AND METHOD - Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart. | 2014-04-17 |
20140107407 | GASTRIC BAND - A gastric band of a belt type is presented for attaching around a circumference of a patient's stomach, so as to define the diameter of the stomach opening. The band comprises outer and inner surfaces, wherein the inner surface engages the stomach, and at least the outer surface is formed by an elongated member substantially non-extendable along a longitudinal axis thereof. A through-going opening is made in the elongated member and is located so as to define an end portion of the band having a predetermined length. An opposite end portion of the band is shaped so as to be insertable into the through-going opening for adjusting a desired inner diameter of the band in its closed operating position and fastening the opposite end portion to the outer surface of the band. | 2014-04-17 |
20140107408 | DEVICE FOR CORRECTING SUNKEN CHEEKS - This invention relates to a cheek plumping apparatus which is comprised of one or multiple cheek pads and the means of attaching the cheek pads to the outer face of an individual's hind teeth. This invention thus causes the individual's cheeks to be pushed outwards and plumped, thereby giving them a more youthful appearance. The invention includes both removable and permanent means of attaching the cheek pads. | 2014-04-17 |
20140107412 | PROTECTIVE SLEEVE AND ASSOCIATED SURGICAL METHOD - An ultrasonic surgical instrument includes an elongate substantially rigid probe and an elongate tubular sheath member. The probe is operatively connected at a proximal end to a source of ultrasonic mechanical vibrations and has a distal tip configured for transmitting ultrasonic vibration energy into organic tissues. The probe longitudinally traverses the sheath member. The sheath member has a distal edge with a first portion on one side of the probe and a second portion on an opposite side of the probe. The first portion of the distal edge of the sheath member is disposed substantially closer than the second portion of the sheath's distal edge to the distal tip of the probe. The second portion of the distal edge is so spaced from the distal tip as to permit effective visualization of the distal tip during use of the instrument. | 2014-04-17 |
20140107413 | ENDOSCOPIC INSTRUMENT HAVING REDUCED DIAMETER FLEXIBLE SHAFT - A medical instrument comprising a flexible, filamentous shaft slideably disposed in a sheath, the instrument including an electronic imaging system comprising an image sensor carried on a distal end portion of the instrument. The shaft may be used as a guidewire for a complementary guided device, or it may be used to carry a functional element for performing a procedure at a target site in a patient's body. In other embodiments, the present invention contemplates a flexible sheath, preferably having a simple tubular construction, with an electronic imaging system at its distal end. The sheath is adapted to slideably receive a shaft, preferably a filamentous shaft, that closely fits the sheath. The shaft carries functional element at its distal end. The instruments according to the present invention may include one or more filaments along their length for deflecting an insertable portion of the instrument. | 2014-04-17 |
20140107414 | Distal Tip Channel Ramp - An endoscope and endoscope shaft having an adaptor that where the internal diameter of the adaptor increases along its longitudinal direction from the proximal end of the adaptor to the distal end of the adaptor. The adaptor guides an instrument through the working channel of the endoscope and prevents bumps from forming in the working channel of the endoscope shaft. | 2014-04-17 |
20140107415 | Auto Zoom for Video Camera - An endoscope, endoscopic system and method for filling a medical display with a medical image involving sizing the medical image so that it covers at least one of the dimensions of the medical display. Automatically sizing the medical image to fit either the vertical, horizontal, or corner-to-corner dimensions of the surgical display, the sizing of the image involving adjusting the image size to account for changing zoom factors, endoscopes and imaging conditions. | 2014-04-17 |
20140107416 | Detachable Shaft Flexible Endoscope - A flexible endoscope includes a handle, a flexible shaft having a distal end and a proximal end, a coupling mechanism releasably attaching the handle to the distal end of the flexible shaft, an illumination unit disposed in the flexible shaft, the illumination unit providing light to an area in front of the distal end of the flexible shaft, and an imaging unit disposed in the flexible shaft, the imaging unit generating image data of the area in front of the distal end of the flexible shaft, wherein the coupling mechanism includes an electrical channel for transmitting electrical power to the illumination unit and the imaging unit, and a data channel for transmitting the image data from the imaging unit. | 2014-04-17 |
20140107417 | Cannula with Integrated Camera and Illumination - A cannula assembly includes a tubular element forming a lumen, a deployable element of a subassembly, and an electronic component mounted to the deployable element. The tubular element has a proximal end and a distal end adapted to be inserted into a body cavity. The deployable element is coupled through the subassembly to the tubular element, and is adapted to transition between a closed position and an open position. The electronic component has at least one imaging device and at least one illumination source. The subassembly, including the deployable element and the electronic component, are releasable from the tubular element. | 2014-04-17 |
20140107418 | DUAL VIEW ENDOSCOPE - An endoscope is provided to examine internal organs with front and rear views. The endoscope comprises a shaft extending from a distal end in a rearward direction along a longitudinal axis towards a proximal end, with the distal and proximal ends defining a hollow channel extended there-through. The endoscope further comprises a first lens positioned adjacent to the distal end and configured to receive a first image in a forward direction along the longitudinal axis, with the forward direction generally 180 degree from the rearward direction. The endoscope further comprises a rearview module positioned adjacent to the distal end. The rearview module comprises a second lens configured to be positioned adjacent to the distal end, and receive a second image in a target direction having a directional component in the rearward direction along the longitudinal axis, independently of the first lens receiving the first image in the forward direction. | 2014-04-17 |
20140107419 | ASSIST ASSEMBLY FOR PROPULSION OF ENDOSCOPE - An assist assembly for propulsion of a tip device of an endoscope in a body cavity includes an attachment sleeve and a support sleeve. A deformable circulation device is disposed to extend over inner and outer surfaces of the support sleeve, for endlessly moving in an axial direction of the tip device. Plural rollers are disposed on the support sleeve in a rotatable manner, for pressing an inner surface of the circulation device. An alignment projection is formed on the inner surface of the circulation device to project at a height L | 2014-04-17 |
20140107420 | TRACK-FORMING DEVICE - A track-forming device can form an insertion route (track) along which a treatment tool is easily inserted. The track-forming device includes: a plurality of track-forming segmented members that are arranged in the longitudinal direction with spaces therebetween; a soft wire that connects the plurality of track-forming segmented members; and a wire pulling section that brings the plurality of track-forming segmented members into contact with each other in the longitudinal direction. When the plurality of track-forming segmented members are brought into contact with each other by the wire pulling section, a predetermined track is formed. | 2014-04-17 |
20140107421 | LIGHTING STRUCTURE AND ENDOSCOPE - A lighting structure includes: an optical transmission medium that transmits pumping light and image light; an objective optical system that is disposed at a distal-end portion of the optical transmission medium; a wavelength conversion unit comprising a fluorescent body that receives the pumping light transmitted through the optical transmission medium and irradiates an object with illuminating light; and a wavelength-selective reflective unit that selectively reflects one of a wavelength of the pumping light and a wavelength of the image light, thereby emits pumping light that is incident thereto through the optical transmission medium into the fluorescent body and emits image light that is incident from the object into the optical transmission medium through the objective optical system. | 2014-04-17 |