14th week of 2013 patent applcation highlights part 34 |
Patent application number | Title | Published |
20130084491 | AMBIENT TEMPERATURE MOLTEN SALT, ELECTRODE, BATTERY, AGENT FOR PREVENTING CHARGE-UP, AND METHOD FOR OBSERVING SAMPLE - An object of the present invention is to provide an ambient temperature molten salt having excellent electron conductivity in addition to ion conductivity. The present invention attains the object by providing an ambient temperature molten salt including a first imidazolium salt having a cationic segment represented by the general formula (1) and an anionic segment represented by MX | 2013-04-04 |
20130084492 | NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY - In a non-aqueous electrolyte secondary battery, a first active material of a positive electrode includes at least one of carbon-coated LiFePO | 2013-04-04 |
20130084493 | NONAQUEOUS-ELECTROLYTE BATTERIES AND NONAQUEOUS ELECTROLYTIC SOLUTIONS - This invention relates to a nonaqueous-electrolyte battery containing a current collector, a positive electrode, a negative electrode, and a nonaqueous electrolytic solution. The positive electrode contains a lithium-containing phosphoric acid compound represented by LixMPO | 2013-04-04 |
20130084494 | SEPARATOR FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY, METHOD FOR PRODUCING THE SAME, AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY - The separator for non-aqueous electrolyte secondary batteries according to the present invention includes at least a resin (A) having a crosslinked structure. The resin having the crosslinked structure is obtained by applying energy rays to at least an oligomer that is capable of being polymerized by irradiation with energy rays, and the resin (A) has a glass transition temperature higher than 0° C. and lower than 80° C. The separator for non-aqueous electrolyte secondary batteries according to the present invention can be produced using a method of the present invention including the steps of applying a separator-forming composition containing an oligomer and a solvent to a base substrate, forming a resin (A) by irradiation with energy rays, and forming pores by drying a coating film after the resin (A) has been formed. Furthermore, the non-aqueous electrolyte secondary battery of the present invention includes the separator for non-aqueous electrolyte secondary batteries according to the present invention. | 2013-04-04 |
20130084495 | POWER STORAGE DEVICE - Provided is a power storage device in which charge/discharge capacity is high, charge/discharge can be performed at high speed, and deterioration in battery characteristics due to charge/discharge is small. The power storage device includes a negative electrode including an active material including a plurality of prism-like protrusions. A cross section of each of the plurality of prism-like protrusions, which is perpendicular to the axis of each protrusion, is a polygonal shape or a polygonal shape including a curve, such as a cross shape, an H shape, an L shape, an I shape, a T shape, a U shape, or a Z shape. The active material including the plurality of prism-like protrusions may be covered with graphene. | 2013-04-04 |
20130084496 | POWER STORAGE DEVICE - Provided are an electrode for a power storage device having much better charge/discharge characteristics and a power storage device using the electrode. A plurality of cavities is provided in a surface of an active material layer over a current collector. A graphene covering the active material layer facilitates rapid charge/discharge and prevents breakdown of the current collector caused by charge/discharge. With improved charge/discharge characteristics, an electrode for a power storage device which does not easily deteriorate and a power storage device using the electrode can be provided. | 2013-04-04 |
20130084497 | NONAQUEOUS ELECTROLYTE BATTERY, BATTERY PACK AND VEHICLE - A nonaqueous electrolyte battery includes a positive electrode, a negative electrode and a nonaqueous electrolyte. The negative electrode contains a lithium compound and a negative electrode current collector supporting the lithium compound. A log differential intrusion curve obtained when a pore size diameter of the negative electrode is measured by mercury porosimetry has a peak in a pore size diameter range of 0.03 to 0.2 μm and attenuates with a decrease in pore size diameter from an apex of the peak. A specific surface area (excluding a weight of the negative electrode current collector) of pores of the negative electrode found by mercury porosimetry is 6 to 100 m | 2013-04-04 |
20130084498 | NEGATIVE ELECTRODE ACTIVE MATERIAL FOR LITHIUM ION BATTERY, AND NEGATIVE ELECTRODE FOR LITHIUM ION BATTERY USING THE SAME - The present invention relates to a negative electrode active material including an Si—Sn—Fe—Cu based alloy, in which an Si phase has an area ratio in a range of from 35 to 80% in the entire negative electrode active material, the Si phase is dispersed in a matrix phase, the matrix phase contains an Si—Fe compound phase crystallized around the Si phase and further contains an Sn—Cu compound phase crystallized to surround the Si phase and the Si—Fe compound phase, the Si—Fe compound phase is crystallized in a ratio of from 35 to 90% in terms of an area ratio in the entire matrix phase, and the matrix phase further contains an Sn phase unavoidably crystallized in the matrix phase in a ratio of 15% or less in terms of an area ratio in the entire matrix phase, | 2013-04-04 |
20130084499 | NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY - In a non-aqueous electrolyte secondary battery, a positive electrode active material includes a carbon-coated lithium vanadium phosphate and a lithium nickel composite oxide. A negative electrode active material includes a carbon-based active material capable of intercalating and deintercalating lithium ions. When a first charge capacity of a negative electrode per unit area is “x” (mAh/cm | 2013-04-04 |
20130084500 | POSITIVE ELECTRODE MATERIAL - A positive-electrode material includes lithium vanadium phosphate particles having an average primary particle diameter from 0.3 μm to 2.6 μm and crystallite sizes from 24 nm to 33 nm. The lithium vanadium phosphate particles are coated with a conductive carbon of a range of 0.5 mass % to 2.4 mass % with respect to a total lithium vanadium phosphate particles. | 2013-04-04 |
20130084501 | ELECTRODE MATERIAL FOR LITHIUM SECONDARY BATTERY, METHOD FOR PRODUCING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME - An electrode material for lithium secondary battery comprises a nanoheterostructure which contains a lithium-ion conductor and an electrode active substance of which one inorganic component is a matrix, and of which the other inorganic component is three-dimensionally and periodically arranged in the matrix, and has a three-dimensional periodic structure whose average value of one unit length of a repeated structure is 1 nm to 100 nm. | 2013-04-04 |
20130084502 | Intermetallic Nanoparticles - A process for preparing intermetallic nanoparticles of two or more metals is provided. In particular, the process includes the steps: a) dispersing nanoparticles of a first metal in a solvent to prepare a first metal solution, b) forming a reaction mixture with the first metal solution and a reducing agent, c) heating the reaction mixture to a reaction temperature; and d) adding a second metal solution containing a salt of a second metal to the reaction mixture. During this process, intermetallic nanoparticles, which contain a compound with the first and second metals are formed. The intermetallic nanoparticles with uniform size and a narrow size distribution is also provided. An electrochemical device such as a battery with the intermetallic nanoparticles is also provided. | 2013-04-04 |
20130084503 | NONAQUEOUS ELECTROLYTE SECONDARY BATTERY - A nonaqueous electrolyte secondary battery provided by the present invention includes an electrode body in which a positive electrode sheet and a negative electrode sheet | 2013-04-04 |
20130084504 | MICROMACHINED ELECTROLYTE SHEET - The disclosure relates to ceramic lithium ion electrolyte membranes and processes for forming them. The ceramic lithium electrolyte membrane may comprise at least one ablative edge. Exemplary processes for forming the ceramic lithium ion electrolyte membranes comprise fabricating a lithium ion electrolyte sheet and cutting at least one edge of the fabricated electrolyte sheet with an ablative laser. | 2013-04-04 |
20130084505 | SOLID ELECTROLYTE MATERIAL AND LITHIUM BATTERY - A main object of the present invention is to provide a Li—La—Zr—O-based solid electrolyte material having favorable denseness. The present invention solves the problem by providing a solid electrolyte material including Li, La, Zr, Al, Si and O, having a garnet structure, and being a sintered body. | 2013-04-04 |
20130084506 | MONITORING ELECTROLYTE CONCENTRATIONS IN REDOX FLOW BATTERY SYSTEMS - Methods, systems and structures for monitoring, managing electrolyte concentrations in redox flow batteries are provided by introducing a first quantity of a liquid electrolyte into a first chamber of a test cell and introducing a second quantity of the liquid electrolyte into a second chamber of the test cell. The method further provides for measuring a voltage of the test cell, measuring an elapsed time from the test cell reaching a first voltage until the test cell reaches a second voltage; and determining a degree of imbalance of the liquid electrolyte based on the elapsed time. | 2013-04-04 |
20130084507 | NON-VOLATILE CATHODES FOR LITHIUM OXYGEN BATTERIES AND METHOD OF PRODUCING SAME - An air lithium battery is provided having two equal halves ( | 2013-04-04 |
20130084508 | OPERATION METHOD OF FUEL CELL SYSTEM - A method of operating a fuel cell system ( | 2013-04-04 |
20130084509 | METHOD AND APPARATUS FOR CONTROLLING FUEL CELL OPERATING CONDITIONS - The disclosure is directed at a method and apparatus for controlling fuel cell operating conditions. The apparatus includes a set of sensors for monitoring the fuel cell operating conditions and a processing unit, in communication with the set of sensors for determining when the fuel cell operating conditions are outside of an acceptable range. When it is determined that the fuel cell operating conditions are outside of the acceptable range, an electrolyser is activated to electrolyse waste liquid water or water vapour to assist in controlling the fuel cell operating conditions. | 2013-04-04 |
20130084510 | FUEL CELL SYSTEM, CONTROL METHOD FOR FUEL CELL SYSTEM, AND DEGRADATION DETERMINING METHOD FOR FUEL CELL STACK - A fuel cell system includes: a fuel cell stack that is formed of a plurality of serially connected fuel-cell cells that use fuel gas and oxidant gas to generate electric power; a detecting unit that detects an output power generated by each of a first fuel-cell cell group and a second fuel-cell cell group that are grouped on the basis of a power generation performance factor; and an operating condition changing unit that changes an operating condition of the fuel-cell cells on the basis of a rate of deviation between the generated output power of the first fuel-cell cell group, detected by the detecting unit, and the generated output power of the second fuel-cell cell group, detected by the detecting unit. | 2013-04-04 |
20130084511 | SOLID OXIDE FUEL CELL STACK - A solid oxide fuel cell stack is disclosed. The solid oxide fuel cell stack may include a first fuel chamber, flow passage pipes, a unit cell, a second fuel chamber, a first oxidizer chamber, a second oxidizer chamber, and a stabilization chamber. The flow passage pipes are fluidly connected to a bottom end of the first fuel chamber. The unit cell, in which a bottom thereof is shielded, is formed to surround the flow passage pipes and forms the flow passage between the flow passage pipes and the unit cell. The second fuel chamber is fluidly connected to a top end of the unit cell and configured to discharge non-reaction gas from the unit cell. The stabilization chamber is formed between the second fuel chamber and the second oxidizer chamber. | 2013-04-04 |
20130084512 | FUEL BATTERY SYSTEM - A fuel battery system of the present invention includes: an alkaline fuel battery; a fuel supply device for supplying a fuel to an anode of the fuel battery; an oxidizing agent supply device for supplying an oxidizing agent to a cathode of the fuel battery; a liquid supply device which supplies a liquid to the cathode; a valve which switches between fluids to be supplied to the cathode; and a control device which controls the switching of the valve. The fuel battery system suppresses the neutralization of an anion-exchange electrolyte due to carbon dioxide in the air, by supplying the liquid from the liquid supply device to the cathode and making the cathode in the state of being immersed in the liquid when the fuel battery stops power generation. | 2013-04-04 |
20130084513 | ENERGY ADJUSTING METHOD - An energy adjusting method for controlling output energy of a fuel cell group, wherein at least one of the fuel cell group and a secondary battery group drives a load is disclosed. The voltage of the fuel cell group is boosted by a boost regulation module to generate a first adjustment voltage. The boost regulation module boosts the voltage of the fuel cell group according to a first control signal. The first adjustment voltage is dropped by a drop regulation module to generate a second adjustment voltage to the load. The drop regulation module drops the first adjustment voltage according to a second control signal. At least one of the fuel cell group, the boost regulation module, the drop regulation module and the load is detected to generate a detection result. The first and the second control signals are generated according to the detection result. | 2013-04-04 |
20130084514 | GAS DECOMPOSITION COMPONENT, AMMONIA DECOMPOSITION COMPONENT, POWER GENERATION APPARATUS, ELECTROCHEMICAL REACTION APPARATUS, AND METHOD FOR PRODUCING GAS DECOMPOSITION COMPONENT - Provided are a gas decomposition component in which an electrochemical reaction is used to reduce the running cost and high treatment performance can be achieved; and a method for producing the gas decomposition component. The gas decomposition component includes a cylindrical MEA | 2013-04-04 |
20130084515 | POLYIMIDE POROUS WEB, METHOD FOR MANUFACTURING THE SAME, AND ELECTROLYTE MEMBRANE COMPRISING THE SAME - Disclosed is a polyimide porous web with good porosity, good dimensional stability, and uniform pore; a method for manufacturing the same; and an electrolyte membrane with improved ion conductivity and good dimensional stability owing to ion conductors uniformly impregnated in the porous web, the polyimide porous web having a porosity of 60% to 90%, wherein not less than 80% of entire pores of the porous web have a pore diameter which differs from an average pore diameter of the porous web by not more than 1.5 μm. | 2013-04-04 |
20130084516 | Poly(Methyl Methacrylate) Additive to Polyelectrolyte Membrane - An ion-conducting membrane for fuel cells includes an ion-conducting polymer having protogenic groups and poly(methyl methacrylate). Characteristically, the ion-conducting layer is planar having a thickness from 1 microns to 200 microns. A membrane electrode assembly includes the ion-conducting membrane interposed between a cathode layer and an anode layer. | 2013-04-04 |
20130084517 | RESIST PROTECTIVE FILM-FORMING COMPOSITION AND PATTERNING PROCESS - A protective film-forming composition comprising a polymer comprising fluorinated alcohol units of the structure: —C(CF | 2013-04-04 |
20130084518 | NEGATIVE CHEMICAL AMPLIFICATION RESIST COMPOSITION, RESIST FILM, AND, RESIST-COATED MASK BLANKS, METHOD FOR FORMING RESIST PATTERN, AND PHOTOMASK, EACH USING THE SAME - Disclosed is a negative chemical amplification resist composition including (A) a polymer compound having a repeating unit (P) represented by the following formula (I) which is stable in acids and alkalis, and a repeating unit (Q) having a phenolic hydroxyl group; (B) a compound capable of generating an acid when irradiated with actinic rays or a radiation; and (C) a cross-linking agent: | 2013-04-04 |
20130084519 | Toner with improved charging - The disclosure describes a toner process in which portion-wise addition of colorant(s) during particle formation is used to control the distribution of colorant within the toner particle, thereby enhancing A zone charge. | 2013-04-04 |
20130084520 | ELECTROSTATIC IMAGE DEVELOPING TONER AND MANUFACTURING METHOD OF THE SAME, ELECTROSTATIC IMAGE DEVELOPER, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD - An electrostatic image developing toner of the exemplary embodiment of the invention contains an amorphous first polyester resin of a polycondensation product of at least a carboxylic acid component and an alcohol component containing rosin, and a second polyester resin having the difference (absolute value) in parameter of solubility relative to the first polyester resin of from about 0.3 (cal/cm | 2013-04-04 |
20130084521 | CARRIER CORE PARTICLES FOR ELECTROPHOTOGRAPHIC DEVELOPER, CARRIER FOR ELECTROPHOTOGRAPHIC DEVELOPER, ELECTROPHOTOGRAPHIC DEVELOPER AND METHOD FOR MANUFACTURING THE CARRIER CORE PARTICLES - The carrier core particles for electrophotographic developer include a core composition expressed by a general formula Fe | 2013-04-04 |
20130084522 | AQUEOUS DISPERSIONS FOR USE AS TONERS - A compound that includes an aqueous dispersion, wherein the dispersion includes a thermoplastic resin and at least one stabilizing agent, and at least one selected from the group consisting of a colorant and a magnetic pigment, wherein the dispersion has an average volume diameter particle size from about 0.05 to about 10 microns is described. | 2013-04-04 |
20130084523 | RESIST COMPOSITIOIN AND METHOD OF FORMING RESIST PATTERN - A method of forming a resist pattern, including: a step (1) in which a resist film is formed by coating a resist composition including a base component (A) that exhibits increased solubility in an alkali developing solution, a photo-base generator component (C) that generates a base upon exposure, an acid supply component (Z) and a compound (F) containing at least one selected from the group consisting of a fluorine atom and a silicon atom and containing no acid decomposable group which exhibits increased polarity by the action of acid on a substrate; a step (2) in which the resist film is subjected to exposure; a step (3) in which baking is conducted after the step (2); and a step (4) in which the resist film is subjected to an alkali development, thereby forming a negative-tone resist pattern, and a resist composition used in the step (1). | 2013-04-04 |
20130084524 | COMPOSITION FOR FORMING LIQUID IMMERSION UPPER LAYER FILM AND METHOD FOR FORMING RESIST PATTERN - A composition for forming a liquid immersion upper layer film, includes a first polymer, a second polymer and a solvent. The first polymer includes a first structural unit having a group represented by a following formula (i). In the formula (i), n is an integer of 1 to 3, and R | 2013-04-04 |
20130084525 | PHOTOACID GENERATOR AND PHOTORESIST COMPRISING SAME - A photoacid generator compound has the formula (I): | 2013-04-04 |
20130084526 | PHOTO-RESIST AND METHOD OF PHOTOLITHOGRAPHY - A photo-resist and a method for performing photolithography using the photo-resist are described. The photo-resist comprises a matrix resin, a first component and a second component. The first component is configured to produce a chemical amplification action and generates a first chemical substance when exposed to a light of a first wavelength band. The first chemical substance will react with the matrix resin to form a latent image. The second component is configured to generate a second chemical substance when exposed to a light of a second wavelength band. The second chemical substance reacts with the first chemical substance to reduce a mass concentration of the first chemical substance. | 2013-04-04 |
20130084527 | POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS - A positive resist composition comprising a polymer having carboxyl groups substituted with an acid labile group having formula (1) exhibits a high contrast of alkaline dissolution rate before and after exposure, a high resolution, a reduced acid diffusion rate, and forms a pattern with good profile, minimal edge roughness, and etch resistance. In formula (1), R | 2013-04-04 |
20130084528 | POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS - A positive resist composition comprising a polymer having carboxyl groups substituted with an acid labile group having formula (1) exhibits a high contrast of alkaline dissolution rate before and after exposure, a high resolution, a reduced acid diffusion rate, and forms a pattern with good profile, minimal edge roughness, and etch resistance. In formula (1), R | 2013-04-04 |
20130084529 | POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS - A positive resist composition comprising a polymer having carboxyl groups substituted with an acid labile group having formula (1), (2) or (3) exhibits a high contrast of alkaline dissolution rate before and after exposure, a high resolution, a reduced acid diffusion rate, and forms a pattern with good profile, minimal edge roughness, and etch resistance. In formula (1), R | 2013-04-04 |
20130084530 | METHOD FOR FABRICATING PATTERNED LAYER - A method for fabricating a patterned layer is disclosed. Firstly, a semiconductor substrate is provided. Then, a precursory gas on the semiconductor substrate is formed. Finally, a patterned layer on the semiconductor substrate is deposited by reacting the precursory gas with at least one electron beam or at least one ion beam. The present invention not only fabricates a patterned layer on the substrate in a single step but also achieves a high lithographic resolution and avoids remains of contaminations by using the properties of the electron beam or the ion beam and the precursory gas. | 2013-04-04 |
20130084531 | METHOD OF PRODUCING ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE - Provided is a method of producing an organic electroluminescence display device including patterning by photolithography, the method including: forming an organic compound layer containing a low-molecular organic electroluminescence material and an intermediate layer for protecting the organic compound layer; forming a resist layer on the intermediate layer; irradiating the resist layer with ultraviolet light through a photomask to partially remove the resist layer in a region irradiated with the ultraviolet light; and removing the organic compound layer in a region from which the resist layer is removed, in which the resist layer includes a layer formed of a positive resist, and the intermediate layer includes a layer formed of a high-molecular organic material having a chain structure, capable of being selectively dissolved in a solvent that dissolves the organic compound layer. | 2013-04-04 |
20130084532 | PHOTOLITHOGRAPHIC METHOD - A method for performing photolithography using a photo-resist is disclosed. The photo-resist comprises a first component and a second component. The method includes providing a substrate having a surface coated with the photo-resist and selectively illuminating a region of the surface of the photo-resist using light in a first wavelength band. The method further includes illuminating the entire surface of the photo-resist using light in a second wavelength band. The first and second wavelength bands are different and may not overlap. The method also includes performing a development process for the photo-resist upon illumination with the light of the first and second wavelength bands. | 2013-04-04 |
20130084533 | Spill proof alcohol burner - A portable alcohol burner is designed to use ethanol as a fuel for indoor/outdoor settings. The burner has a fuel chamber filled with ceramic fiber filler permeated with alcohol. A perforated baffle cage is fitted in the housing and is completely surrounded by the filler material. As alcohol vapors escape from the fuel chamber and rise through the perforations in the baffle cage they can be ignited to create a desired pleasing flame pattern. | 2013-04-04 |
20130084534 | COMBUSTOR AND METHOD FOR SUPPLYING FUEL TO A COMBUSTOR - A combustor includes an end cap having upstream and downstream surfaces and a cap shield surrounding the upstream and downstream surfaces. First and second sets of premixer tubes extend from the upstream surface through the downstream surface. A first fuel conduit supplies fuel to the first set of premixer tubes. A casing circumferentially surrounds the cap shield to define an annular passage, and a second fuel conduit supplies fuel through the annular passage to the second set of premixer tubes. A method for supplying fuel to a combustor includes flowing a working fluid through first and second sets of premixer tubes, flowing a first fuel into the first set of premixer tubes, and flowing a second fuel through an annular passage surrounding the end cap and into the second set of premixer tubes. | 2013-04-04 |
20130084535 | MULTI-COLORED, MULTI-SCENTED CANDLE - The invention relates to a multi-colored, multi-scented candle, comprising a solidified block of fuel and a wick embedded therein, wherein the solidified block of fuel comprises two, three or more distinct fuel members strung on the wick and partially or completely embedded in the outer fuel portion of the solidified block of fuel, wherein a first member and a second member of said distinct fuel members are adjacent and have different scents and different colors. | 2013-04-04 |
20130084536 | METHODS AND APPARATUS FOR AN ORTHODONTIC HEADGEAR SLIP - A method and apparatus for an orthodontic headgear slip, comprising a substantially rectangular body having a pair of ends that are each coupled together, a front side, a back side, a top, and a bottom. The rectangular body comprises a longitudinal opening for receiving a headgear neck-strap on the top of the body and a first and a second opening on the front of the body. The openings are spaced and sized to allow for a first and a second headgear attachment mechanism to be fed from inside of the body to outside of the body. | 2013-04-04 |
20130084537 | APPARATUS AND METHOD FOR USE IN CREATING DENTAL PROSTHETICS - An apparatus and method for creating dental prosthetics with greater accuracy and consistency is provided. The apparatus includes a base, an ear mount portion for making contact with a patient's head such that the patient's temporomandibular joints are maintained in a fixed level position relative to the base, a chin mount portion for making contact with the patient's chin and nose bridge such that the chin mount portion maintains the patient's head in a perpendicular orientation relative to the base, a bite fork portion including a bite fork which may be inserted into the patient's mouth for the purpose of obtaining the patient's bite registration information, and a camera mount portion including a camera oriented toward the patient's face. | 2013-04-04 |
20130084538 | APPARATUS AND METHOD FOR USE IN CREATING DENTAL PROSTHETICS - An apparatus and method for creating dental prosthetics with greater accuracy and consistency is provided. The apparatus includes a base, an ear mount portion for making contact with a patient's head such that the patient's temporomandibular joints are maintained in a fixed level position relative to the base, a chin mount portion for making contact with the patient's chin and nose bridge such that the chin mount portion maintains the patient's head in a perpendicular orientation relative to the base, a bite fork portion including a bite fork which may be inserted into the patient's mouth for the purpose of obtaining the patient's bite registration information, and a camera mount portion including a camera oriented toward the patient's face. | 2013-04-04 |
20130084539 | DENTAL IMPRESSION TRAY - A dental impression tray includes a tray body | 2013-04-04 |
20130084540 | STOPPER AND STOPPER SET - A stopper Y is cylindrically formed in its entirety and inserted and attached from a top side of a blade Xc of a drill X having a flange Xa projecting at a shank Xb. The stopper has a through hole to be inserted by the blade Xc of the drill X and includes a drill blade entering depth regulating part Ya and a drill holding part Yb. The drill blade entering depth regulating part Ya has a height regulating a entering depth of the blade Xc of the drill X in a jawbone of the lost tooth part. The drill holding part Yb has a plurality of slits Yba formed along the axial direction of the stopper from an end opposite to the drill blade entering depth regulating part Ya, detachably engages to the flange Xa of the drill X, and holds the drill X by elasticity. | 2013-04-04 |
20130084541 | IMPLANT SYSTEM - An implant system ( | 2013-04-04 |
20130084542 | METHOD FOR IMPROVING PRODUCTIVITY AND PERSONALIZATION FOR DENTAL PROSTHESES - The present disclosure describes a method for increasing the speed in setting artificial teeth in full dentures or dental prostheses, the method comprising providing premade tooth segments, the premade tooth segments comprising at least one tooth that may be preset into a gingival roll manufactured with either the individual teeth connected together in the gingival roll or by a mid-tooth connection at the mesial and distal surfaces (the sides of a tooth) of each tooth in the segment; setting the premade tooth segments into a wax bite rim; fitting the wax bite rim to the patient's mandibular or maxillary arch; and curing the wax bite rim. Another aspect of the disclosure includes a method for individualizing the denture or dental prosthesis whereby the incisors can be manipulated to create a personal and natural appearance. | 2013-04-04 |
20130084543 | THIOL-ENE POLYMERIZATION WITH VINYLESTERS AND VINYLCARBONATE - The present disclosure is directed, in part, to a curable composition, a method for augmenting a structure in a patient with a resorbable biocompatible polymer, and a biodegradable, resorbable implant comprising a biocompatible copolymer. An exemplary embodiment of the curable composition comprises (a) 60 wt. % to 95 wt. % of one or more vinyl ester monomers and/or vinylcarbonate monomers, wherein said one or more vinyl ester monomers and/or vinylcarbonate monomers are respectively selected from compounds of the general formulas (I) and (II) below: | 2013-04-04 |
20130084544 | Cavitation Medication Delivery System - Systems and methods for delivering a substance to a target region in vapor form are provided. A fluid is placed within an interaction zone, where the interaction zone is a volume that extends into the target region or that is adjacent to the target region. A fiber optic tip is placed within the interaction zone. The fiber optic tip contains the substance that is transparent to a first wavelength of energy and that substantially absorbs a second wavelength of energy. A vapor bubble is created within the interaction zone by exposing the fluid to electromagnetic radiation at the first wavelength, where the radiation at the first wavelength is substantially absorbed by the fluid. The substance is released in vapor form into the vapor bubble by exposing the substance to electromagnetic radiation at the second wavelength. The fiber optic tip emits the radiation at the first and second wavelengths. | 2013-04-04 |
20130084545 | Pressure Wave Root Canal Cleaning System - Systems and methods are provided for cleaning or disinfecting a target region. A fluid including a plurality of gas bubbles is placed into an interaction zone. The interaction zone is a volume that extends into the target region or that is adjacent to the target region. The fluid in the interaction zone is exposed to electromagnetic radiation, where the electromagnetic radiation has a wavelength that is substantially absorbed by the fluid. The fluid in the interaction zone substantially absorbs the electromagnetic radiation to create an acoustic shock wave and a pressure wave. The acoustic shock wave and the pressure wave cause a movement of the fluid and cavitation effects that are configured to clean or disinfect the target region. | 2013-04-04 |
20130084546 | COMPOSITIONS FOR INFILTRATION AND/OR SEALING OF HARD TOOTH TISSUE AND CORRESPONDING METHODS - A method for infiltration and/or sealing of hard tooth tissue and for detection of caries in the infiltrated region or under the seal by means of fluorescence, is described. The method includes applying a composition comprising a filler system consisting of or comprising inorganic filler particles surface-modified by means of organic structural elements, wherein the organic structural elements can be reacted with an organic binder system to form covalent bonds, wherein the filler particles of the composition have an average particle size in the range between 1 nm and 150 nm, and an organic binder system comprising one or more polymerizable monomers, wherein the filler system is dispersed in the organic binder system (b). The infiltrated or sealed surface of the hard tooth tissue is then irradiated with excitation radiation which causes emission of fluorescence radiation. The fluorescence radiation data is recorded and used to detect curies. | 2013-04-04 |
20130084547 | Illuminated Child's Activity Toy - An illuminated child's activity toy in which a housing is provided on which opaque drawing sheets can be mounted. The housing includes an illumination system that can be used to back-light the surfaces of the housing. Using a scraping tool, a child can remove the opaque material from the drawing sheet to reveal the illuminated base and optionally, a design which has been pre-printed on the drawing sheet. The illuminated toy can be viewed using 3D glasses to enhance the visual appearance of the toy. Additionally, the toy can be used as a customized nightlight of the child's own design. A novel child's activity toy is provided. | 2013-04-04 |
20130084548 | DEVICE TO THREE-DIMENSIONALLY DISPLAY COLORS OF A COLOR MODEL - A device to three-dimensionally display colors of a color model is provided. The device includes a plurality of interconnected top panels. The top panels are arranged in a circle about a central axis to display primary, secondary and tertiary colors of the color model in a predetermined spatial relationship at the top surface of the device. The device further includes a plurality of interconnected side and bottom panels. Left and right surfaces of the side panels, the lower surfaces of the top panels and the upper surfaces of the bottom panels form the side surfaces of the device and display the primary, secondary and tertiary colors of the color model at the side surfaces. | 2013-04-04 |
20130084549 | LITERACY EDUCATION SYSTEM FOR STUDENTS WITH AUTISTIC SPECTRUM DISORDERS (ASD) - A literacy system provides teaching for reading and writing skills particularly adapted to students with autistic spectrum disorders (ADS). In one embodiment, the literacy system may include exercises for teaching visual sequencing, motor skills, phonology, semantics, syntax, and text. The literacy system may have a pre-reading section, which includes exercises for developing visual sequencing skills and motor skills prior to teaching the skills of reading and writing words. | 2013-04-04 |
20130084550 | Potty Training Device - A potty training device has a backsplash/shield designed to attach and conform to an inner rim of a toilet bowl. The distal ends of the backsplash/shield include structures for fixedly connecting the backsplash to the inner rim of the toilet. The backsplash further has a structure fixedly attached to the front of the backsplash at or near the center, bottom of the backsplash that extends from the front of the backsplash. The structure defines a target for providing young boys to aim at while urinating standing up. The backsplash provides protection from urine deflected by the target. The backsplash and target may further define a sporting theme, for example, a basketball theme. The potty training device may include electronic sensors and/or displays. | 2013-04-04 |
20130084551 | Child Learning And Safety Device And Method Of Use - A child learning and safety device comprising: a housing, where the housing contains a plurality of internal components; an attachment means attached to the housing, wherein the attachment means enables the housing to wrap around a body part of a child user; an audio device as one of the internal components, where the audio device plays audio files; a location processor as one of the internal components, where the location processor monitors a location of the child user; one or more location sensors attached to a fixture within a building, where the location sensor activate an alarm within the location processor when the location processor comes within a predetermined distance of the location sensor; and a set of speakers positioned on the housing, where the set of speakers play the audio files and where the set of speaker sound the alarm when the location processor is activated. | 2013-04-04 |
20130084552 | WAGER GAMING VOTING LEADERBOARD - Disclosed herein are techniques and equipment for providing a voting point leaderboard system. Players playing wagering games may be awarded voting points for use in a poll with a plurality of candidates in exchange for game-play related activity. Players voting for the winning candidate in the poll may be given an award. Polls may include candidates which may be involved in a real-world contest. Players may be rewarded for voting for the candidate which wins the real-world contest. | 2013-04-04 |
20130084553 | INFORMATION PROVIDING SYSTEM - In an information providing system, a transmitter/receiver of an information providing device serves as a relay station to allow wireless data transmission and reception between the information providing device and a tablet and between the information providing device and each of response clickers provided for individual responders in audience. The information providing device wirelessly receives data from the tablet and from each individual response clicker in a specified time interval of data transmission after transmission of a transmission approval. The information providing device transmits the transmission approval to a transmitter/receiver of the tablet at a higher frequency than a frequency of transmitting the transmission approval to a transmitter/receiver of each of the response clickers. This effectively increases accumulation of the time interval of data transmission from the tablet to the information providing device. | 2013-04-04 |
20130084554 | CUSTOMIZED QUESTION PAPER GENERATION - The present subject matter relates to a method for customized question paper generation. The method includes assigning at least one key value to each of a plurality of questions, and storing the questions along with the at least one associated key value in a question bank. The method further includes fetching the stored questions based on rules in a question paper template, where the rules are based on the at least one key value. Furthermore, the method includes validating the fetched questions based on at least one constraint and generating the question paper based on the validating. | 2013-04-04 |
20130084555 | INFORMATION PROVIDING SYSTEM - An information providing system is configured to provide each of students with an image of a material taken with a camera of an information providing device and allow interaction with the student. The teacher operates a tablet to set a plurality of answer options as available response choices for a question, such that the number of answer options is equal to or less than the number of answer buttons provided on each response clicker. The response clicker receives answer options specification data for specifying the answer options set by the teacher and provides initial notification that notifies each of the students of the answer buttons respectively corresponding to the plurality of answer options specified by the received answer options specification data. | 2013-04-04 |
20130084556 | SYSTEM AND METHOD FOR SIMULATING GOODS IN BULK - A retail display provides a simulation of stacked, palletized goods. The display simulates stacked bulk goods in bulk with a fabric cover draped on a tubular frame, where graphics and/or designs are applied to the fabric cover to simulate images of goods or stacks of goods. The fabric cover can be secured to the frame, both of which can be secured separately or together to a pallet as a support. The fabric cover and frame can be implemented in various shapes and sizes to accommodate different pallet sizes while simulating stacked bulk goods. The display eliminates the risks involved in providing actual bulk goods in palletized form for marketing and promotion purposes. The fabric cover is provided with various features, such as wind slits or rain holes to permit the display to withstand various environmental conditions. | 2013-04-04 |
20130084557 | SYSTEM, APPARATUS AND METHOD FOR EDUCATION THROUGH INTERACTIVE ILLUSTRATION - Systems, methods, and apparatus are described herein that facilitate education through an interactive illustration. The systems, methods and apparatuses can facilitate both the design of a course employing the interactive illustration at an instructor interface and education utilizing the course at an educational terminal. The design of the course can be based on a selection of an image, a selection of an activity, a selection of a development level of a student and selection of a work stage. The same image can be utilized for different activities, development levels and work stages. Additionally, tools utilized with the interactive image can be the same for different images, activities, development levels and work stages. The tools can also be the same for the design of the course and the study utilizing the course. | 2013-04-04 |
20130084559 | Methods of Sustaining Culture Viability - The present invention relates to methods for sustaining a microbial culture during periods of limited substrate supply. In accordance with the methods of the invention, a microbial culture comprising carboxydotrophic bacteria can be sustained during periods of limited substrate supply by maintaining the temperature of the microbial culture at a temperature below an optimum operating temperature. Examples of periods of limited substrate supply include when the microbial culture is transported to a remote location or during time when it is stored. | 2013-04-04 |
20130084560 | ANALYSIS OF A MICRONEUTRALIZATION ASSAY USING CURVE-FITTING CONSTRAINTS - A method and apparatus are disclosed for analyzing a microneutralization assay. Specifically, an automated process can be used to read the optical density of multiple samples in a microneutralization assay and plot the results using one or more constraints. A particular constraint that can be used is a maximum optical density that is read from a sample. Using the plotted curve, a neutralization titer is determined, which is the highest dilution at which a virus is effectively blocked. Other constraints can also be used. For example, a constraint can be based on using a cell control optical density as a lower asymptote and a virus control optical density as an upper asymptote. When multiple constraints are used, analysis is performed to determine which constraint provided the most accurate curve fit. | 2013-04-04 |
20130084561 | BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY - The invention provides compositions and methods for the detection of biological targets, (e.g. nucleic acids and proteins) by nucleic acid templated chemistry, for example, by generating fluorescent, chemiluminescent and/or chromophoric signals. | 2013-04-04 |
20130084562 | TETHERED ENZYME MEDIATED NUCLEIC ACID DETECTION - The present invention relates to methods and compositions for detecting a target nucleotide sequence in a sample. In particular, the methods and compositions of the present invention employ a reporter enzyme tethered to a solid support via a tether nucleotide sequence. A disclosed method for detecting a target nucleotide sequence comprises providing a linker nucleotide sequence comprising a probe sequence that can hybridize to the target sequence and a trigger which can hybridize to the tether nucleotide sequence when the probe sequence binds to the target. The linker nucleotide can have a stem-loop structure. When the trigger hybridizes to the tether nucleotide sequence, the tether is able to be digested by a nuclease, releasing the reporter enzyme from the solid support. The activity of the released reporter enzyme on a spatially or temporally separated substrate generates a detectable signal. In some embodiments, the reporter enzyme releases a feedback trigger that can hybridize to the tether nucleotide sequence and release further reporter enzymes, amplifying the signal via a feedback loop. | 2013-04-04 |
20130084563 | CO-CULTURING MAMMALIAN EMBRYONIC STEM CELLS WITH HUMAN FORESKIN FIBROBLASTS - A cell culture comprising human foreskin cells, the human foreskin cells being capable of maintaining stem cells in an undifferentiated state when co-cultured therewith. | 2013-04-04 |
20130084564 | ASSESSMENT OF CANCER RISK BASED ON RNU2 CNV AND INTERPLAY BETWEEN RNU2 CNV AND BRCA1 - Polynucleotides useful for detecting copy number variation of RNU2 sequences and methods of assessing risk of developing breast or ovarian cancer using molecular combing and/or detection or quantification of BRCA1 expression. | 2013-04-04 |
20130084565 | VERSATILE, VISIBLE METHOD FOR DETECTING POLYMERIC ANALYTES - The invention provides methods to detect or determine the presence or amount of a polymeric analyte in a sample, which employ magnetic substrates and subjects the sample and the magnetic substrate to forms of energy so as to induce aggregate formation. | 2013-04-04 |
20130084566 | FETAL METHYLATION MARKERS - This application describes the discovery that, in a pregnant woman, certain genes (such as RASSF1A, APC, CASP8, RARB, SCGB3A1, DAB2IP, PTPN6, THY1, TMEFF2, and PYCARD) originated from a fetus are highly methylated, whereas the same genes of maternal origin are unmethylated. This discovery allows the easy detection of one or more of these methylated fetal genes in a biological sample from a pregnant woman, serving as a universal indicator of the presence of fetal DNA in the sample. These fetal methylation markers are particularly useful as positive controls for a non-invasive analytical process during which the quality and quantity of fetal DNA are monitored. These newly identified fetal markers can also be measured directly for diagnosis of certain pregnancy-related conditions. | 2013-04-04 |
20130084567 | Systems and Methods of Sample Processing and Temperature Control - Systems and methods of sample processing and temperature control are disclosed. The invention may especially relate to temperature control, and may in some embodiments be methods of temperature control of an automated sample processing system and methods of automated sample processing. Specifically, the present invention provides temperature control in relation to sample processing systems and methods of processing samples, and in some embodiments provides temperature control in relation to sample carriers and processing materials such as reagents. Corresponding systems and devices are disclosed, including sample processing systems ( | 2013-04-04 |
20130084568 | Probe, and polymorphism detection method using the same - The present disclosure relates to a probe for detecting a polymorphism, a method of detecting a polymorphism, a method of evaluating the efficacy of a drug, and a reagent kit for detecting a polymorphism. | 2013-04-04 |
20130084569 | NANOMOTORS AND MOTION-BASED DETECTION OF BIOMOLECULAR INTERACTIONS - Techniques and systems are disclosed for detecting biomolecular interactions based on the motion of nanomotors. In one aspect, a method of detecting biomolecular interactions based on a motion of a nanomachine includes functionalizing a nanomachine with a capture probe adapted to interact with biological targets; and detecting a presence of the biological targets in an environment based on a motion of the nanomachine. | 2013-04-04 |
20130084570 | METHODS OF EVALUATING RESPONSE TO CANCER THERAPY - A method of evaluating a cancer patient comprising evaluating gene expression levels in a patient sample, calculating a predictor score using the gene expression levels, and assessing the likelihood of a therapeutic outcome using the predictor score is disclosed. | 2013-04-04 |
20130084571 | METHYLATION PROFILING OF DNA SAMPLES - The present disclosure relates to methodology for fast and cost-effective identification of the source of DNA samples. DNA samples obtained from unknown or unrecognized tissues or cell types are analyzed according to the methodology described herein, yielding an identification of the tissue and/or cell type source. Identification is based on sequential biochemical procedures including methylation sensitive/dependent restriction and polymerase chain reaction, followed by analysis of the data. All biochemical steps are performed in a single test tube. The disclosure has immediate applications in forensic science for identification of the tissue source of DNA obtained from biological stains. The disclosure also has immediate applications in cancer diagnosis for identification. | 2013-04-04 |
20130084572 | CALIBRATIONS AND CONTROLS FOR DROPLET-BASED ASSAYS - System, including methods and apparatus, for performing droplet-based assays that are controlled and/or calibrated using signals detected from droplets. | 2013-04-04 |
20130084573 | Cancer Diagnosis by Measuring Polyisoprenylated Methylated Protein Methyl Esterase Activity - Methods for cancer diagnosis, making decisions on appropriate cancer treatment, awareness of a predisposition to cancer and potential cancer prevention, and monitoring of cancer therapy by measuring the activity of PMPMEase. | 2013-04-04 |
20130084574 | Chromosome Conformation Analysis - Disclosed herein are compositions, methods and kits for analyzing three-dimensional chromatin and/or chromosome conformation. Method are also disclosed for using the methods disclosed herein for diagnosing diseases such as cancer. | 2013-04-04 |
20130084575 | METHOD AND DEVICE FOR REPLICATING A CELL COLONY IN CULTURE FOR EARLY ANALYSIS - The present invention provides an apparatus comprising, in combination: (a) a cell culture plate, the cell culture plate comprising a first substrate and a plurality of cell carriers on the substrate in a first pattern; and (b) a cell replication plate, the cell replication plate comprising a second substrate and a plurality of cell sampling posts on the second substrate in a second pattern corresponding to the first pattern. Each of the sampling posts is configured to align with a respective one of the cell carriers in a position in which cells growing on the cell carrier propagate onto the sampling post; so that a plurality of distinct cell colonies growing on the cell culture plate are replicated on the cell replication plate. Methods of using the same are also described. | 2013-04-04 |
20130084576 | MODIFIED NUCLEOSIDES, ANALOGS THEREOF AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM - The present invention provides modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom. More particularly, the present invention provides modified nucleosides and analogs thereof that are useful for incorporation at the terminus of an oligomeric compound. Such oligomeric compounds can also be included in a double stranded composition. In some embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. | 2013-04-04 |
20130084577 | METHODS OF CHARACTERIZING HOST RESPONSIVENESS TO INTERFERON BY EX VIVO INDUCTION OF INTERFERON-RESPONSIVE MARKERS - Embodiments of the invention relate generally to ex vivo methods of quantifying expression of interferon responsive genes and characterizing an individual's potential responsiveness to interferon administration. Certain embodiments relate to methods to monitor the efficacy of ongoing interferon therapy by evaluating expression of interferon responsive genes before and after interferon administration. | 2013-04-04 |
20130084578 | BREAST CANCER RELATED GENE ZNFN3A1 - Objective methods for detecting and diagnosing breast cancer (BRC) are described herein. Also described are methods of treating and preventing breast cancer and breast cancer metastasis as well as methods of assessing the prognosis of a breast cancer subject and the efficacy of a breast cancer therapy. In one embodiment, the diagnostic method involves determining the expression level of ZNFN3A1, a gene whose expression is markedly elevated in breast cancers, that therefore can be used to discriminate between BRC cells and normal cells. The present invention further provides methods of screening for therapeutic agents useful in the treatment of BRC, methods of treating BRC and method for vaccinating a subject against BRC. | 2013-04-04 |
20130084579 | DRUG SUSCEPTIBILITY USING RARE CELL DETECTION SYSTEM - Methods for determining the efficacy of a given drug for a specific patient with cancer in vitro prior to, or after, the initiation of treatment of the patient are disclosed. Blood from the cancer patient is separated into an assay test tube and a control test tube. The blood in the assay test tube is exposed to a cancer drug. The two test tubes are then visually examined and compared to determine the effect of the cancer drug on cancer cells, other rare cells in the blood, or on normal constituents of the blood of a cancer patient. | 2013-04-04 |
20130084580 | CHROMATOGRAPHIC KIT AND CHROMATOGRAPHY METHOD - A chromatographic kit is provided including a labeling substance holding area having a labeling substance modified with a first binding substance of a test substance, and a labeling substance capturing area having a second binding substance of the test substance or a binding substance of the first binding substance in this order from upstream to downstream of a development direction of a test sample including the test substance, and further including an area having a color developing reagent in order to detect a first amplification reagent of two types of amplification reagents used to amplify the signal of the labeling substance when detecting the labeling substance. | 2013-04-04 |
20130084581 | Method of Identifying Transmembrane Protein-Interacting Compounds - A method for screening compounds for their ability to interact with transmembrane proteins is provided. Also provided is a method for determining whether proteins such as transmembrane proteins are able to oligomerise. | 2013-04-04 |
20130084582 | SEROLOGICAL MARKERS FOR DETECTING COLORECTAL CANCER AND THEIR APPLICATION FOR INHIBITING COLORECTAL CANCER CELLS - Embodiments relate to serological markers for detecting the colorectal cancer and applications of the serological markers. A phospholipid scramblase1 (PLSCR1), a stomatin-like protein 2 (STOML2) or a transport protein Sec61β (SEC61β) increases expression in the blood at the earlier stage of the colorectal cancer. Detecting the expression of the PLSCR1, STOML2 or SEC61β protein or an induced autoantibody of each protein in a blood sample is used to diagnose the colorectal cancer. Moreover, the serological marker improves the detection efficiency and the sensitivity in detecting the colorectal cancer and is used to predict the prognosis. The serological markers are applied in preparing a detection device or inhibiting the growth of the colorectal cancer cells. | 2013-04-04 |
20130084583 | VARIANTS OF VEGFR AND THEIR USE IN THE DIAGNOSIS AND TREATMENT OF PREGNANCY ASSOCIATED MEDICAL CONDITIONS - An isolated polypeptide comprising an amino acid sequence at least 70% homologous to SEQ ID NO: 4 and an isolated polynucleotide encoding same are disclosed. A polynucleotide comprising a nucleic acid sequence capable of specifically hybridizing to the isolated polynucleotide and an isolated antibody comprising an antigen recognition domain which specifically binds the isolated polypeptide are also disclosed. Pharmaceutical compositions, methods of diagnosing and treating comprising same are also disclosed. | 2013-04-04 |
20130084584 | METHOD TO DETECT TISSUE DEGRADATION LEADING TO INFLAMMATION - This invention relates generally to a method, an assay and a kit for determining a tissue degradation process that leads to inflammatory responses opening up for a vicious circle of increased tissue destruction. More specifically the invention relates to kits and methods for an assay that can analyzee human samples, for the presence of a COMP fragment complex that have activated complement exemplified by the complex between COMP and complement factor C3b or natural breakdown fragments of C3b. | 2013-04-04 |
20130084585 | IMMUNOASSAY FOR CHROMOGRANIN A, ANTIBODIES AND KIT - The invention relates to monoclonal antibodies which are reactive with an epitope in the polypeptide represented by amino acid sequence 236 to 251 or 264 to 279 of the human CGA amino acid sequence. The invention further relates to the use of these monoclonal antibodies in an immunoassay for CGA, to immunoreagents comprising any of these two antibodies, and to test kits for the determination of CGA containing immunoreagents based on both of the monoclonal antibodies. | 2013-04-04 |
20130084586 | RAPID, SPECIFIC AND SENSITIVE IMMUNOASSAYS FOR THE DETECTION OF HIGHLY VARIABLE GRAM NEGATIVE BACTERIAL ANTIGENS - Methods for the detection, identification and quantification of gram negative bacteria and gram negative bacterial antigens are rapid, efficient and highly specific. Compositions for the detection and identification of highly variable serogroups are provided. | 2013-04-04 |
20130084587 | Levels of cytokeratins in blood and body fluids as biomarkers for cancer screening, diagnosis and treatment monitoring - Cytokeratins are intermediate filaments in the epithelial cells. Human cancers are malignant counterparts of normal epithelia. Human cancer cells express various kinds of cytokeratins dependent upon the specific cancer cell type. Pathologists have been using cytokeratin immunostaining for classification of tumor origins and cancer types. We claim that the protein levels of cytokeratin 7 (CK7) in the blood and/or body fluids are proportional to the tumor burden, and these protein levels of CK7 can be used as biomarkers for cancer screening, diagnosis and treatment monitoring. | 2013-04-04 |
20130084588 | RAPID AND SENSITIVE DETECTION OF BACTERIA IN BLOOD PRODUCTS, URINE, AND OTHER FLUIDS - The invention provides methods of detecting bacteria in fluids, including blood, platelets and other blood products for transfusion, and urine. The methods are based on lysing the bacteria to release ATP and detecting the ATP. Eukaryotic cell contamination is a problem to be overcome, because eukaryotic cell contain large amounts of ATP. Thus, some of the methods involve separating intact eukaryotic cells (e.g., platelets) from intact bacterial cells before lysing the bacterial cells to release ATP, contacting the ATP with an ATP-consuming enzyme that catalyzes a reaction, and monitoring the enzyme-catalyzed reaction. Typically, the enzyme is luciferin, and the reaction is monitored by detecting light produced by the luciferin. Other methods of the invention involve contacting a fluid sample with a support surface that binds bacterial cells, lysing the bacterial cells to release ATP, contacting the ATP with an ATP-consuming enzyme, and monitoring the enzyme-catalyzed reaction. Apparatuses for carrying out the methods are also disclosed. | 2013-04-04 |
20130084589 | HAND-HELD TEST METER WITH PHASE-SHIFT-BASED HEMATOCRIT MEASUREMENT CIRCUIT - A hand-held test meter for use with an analytical test strip in the determination of an analyte in a bodily fluid sample includes a housing; a microcontroller block disposed in the housing; and a phase-shift-based hematocrit measurement block. The phase-shift-based hematocrit measurement block includes a signal generation sub-block, a low pass filter sub-block, an analytical test strip sample cell interface sub-block, a transimpedance amplifier sub-block, and a phase detector sub-block. In addition, the phase-shift-based hematocrit measurement block and microcontroller block are configured to measure the phase shift of a bodily fluid sample in a sample cell of an analytical test strip inserted in the hand-held test meter and the microcontroller block is configured to compute the hematocrit of the bodily fluid sample based on the measured phase shift. | 2013-04-04 |
20130084590 | ANALYTICAL TEST STRIP WITH BODILY FLUID PHASE-SHIFT MEASUREMENT ELECTRODES - An analytical test strip (“ATS”) for use with a hand-held test meter (“HHTM”) in the determination of an analyte in a bodily fluid sample (“BFS”) includes a first patterned conductive layer with a working electrode and a reference electrode, as well as a method for determining an analyte in BFS. The ATS also includes an enzymatic reagent layer disposed on the working electrode, a patterned spacer layer disposed over the first patterned conductive layer and configured to define a sample chamber (“SC”) within the ATS, and a second patterned conductive layer disposed above the first patterned conductive layer. The second patterned conductive layer includes a first phase-shift measurement electrode and a second phase-shift measurement electrode, which electrodes are disposed in the SC and are configured to measure, along with the HHTM, a phase shift of an electrical signal forced through a BFS introduced into the SC during the ATS' use. | 2013-04-04 |
20130084591 | ANALYTICAL TEST STRIP WITH ISOLATED BODILY FLUID PHASE-SHIFT AND ANALYTE DETERMINATION SAMPLE CHAMBERS - An analytical test strip (“ATS”) for use with a hand-held test meter in the determination of an analyte in a bodily fluid sample includes an electrically insulting substrate, a first patterned conductor layer disposed on the electrically insulating substrate and having a working electrode and a reference electrode. The ATS also includes an enzymatic reagent layer disposed on the working electrode, a first patterned spacer layer disposed over the first patterned conductor layer and defining both a first sample-receiving channel and an analyte determination sample chamber within the ATS, and a second patterned spacer layer disposed over the first patterned spacer layer and defining at least a second sample-receiving channel. The ATS further includes a bodily fluid phase-shift sample chamber in fluidic communication with the second sample-receiving channel. The first sample-receiving channel and analyte determination sample chamber are isolated from the second sample-receiving channel and bodily fluid phase-shift sample chamber. | 2013-04-04 |