| 14th week of 2015 patent applcation highlights part 41 |
| Patent application number | Title | Published |
|---|
| 20150093708 | SUBSTITUTED ARYL ONIUM MATERIALS - Acid generators comprising a carbocyclic or heteroaromatic group substituted with at least one diester moiety are provided. These acid generators are particularly useful as a photoresist composition component. | 2015-04-02 |
| 20150093709 | ARYL ACETATE ONIUM MATERIALS - Acid generators comprising a carbocyclic aryl or heteroaromatic group substituted with at least one acetate moiety are provided. These acid generators are particularly useful as a photoresist composition component. | 2015-04-02 |
| 20150093710 | APPARATUS FOR HEATING PLASTIC BITS - An apparatus and a corresponding method for heating plastic bits, including a heating zone in which introduced plastic bits can be heated, and a heating device which is suited to conduct heat into the heating zone, the apparatus further including filling bodies which can be introduced into the heating zone and are suited to give off absorbed heat to the plastic bits in the heating zone. | 2015-04-02 |
| 20150093711 | HEAT TREATMENT FURNACE AND HEAT TREATMENT DEVICE HAVING THE SAME - A heat treatment furnace of an embodiment includes a chassis, a heater to heat an inside of the chassis, a table rotatably arranged in the chassis, in which an opening portion is formed at a central axis side, and a guide which is fixed inside the chassis, is arranged above the table, and is formed so as to become in a spiral shape from an outer circumferential side of the table toward the opening portion. | 2015-04-02 |
| 20150093712 | RETAINING BAR FOR HEAT FURNACE RECEPTACLES, HEAT FURNACE RECEPTACLE SUPPORTING ASSEMBLY COMPRISING RETAINING BAR AND HEAT FURNACE COMPRISING SAME - A retaining bar to be used in combination with a heat furnace supporting assembly for supporting at least one receptacle. The retaining bar comprises at least one single piece elongated body having a finite length and at least one receptacle receiving cavity defined therein and extending along a section of the length of the body. Each one of the at least one receptacle receiving cavity is configured to receive therein one of a bottom section and an upper section of one of the at least one receptacle. A heat furnace receptacle supporting assembly comprising such a retaining bar and a heat furnace provided with the heat furnace receptacle supporting assembly are further provided. | 2015-04-02 |
| 20150093713 | RELEASE AGENT RECEPTACLE - The present disclosure includes method, system, apparatus, and indicator embodiments. One apparatus includes an appliance for placement over one or more teeth and a release agent receptacle including an outer portion provided on appliance surface, an inner portion provided within the outer portion, and one or more apertures formed in the outer portion. | 2015-04-02 |
| 20150093714 | METHOD, SYSTEM AND MODEL FOR INDIRECT BONDING - A physical model of at least a portion of a patient's dentition has model dental surfaces corresponding to real dental surfaces of the patient's dentition. The physical model includes one or more targets, each configured for facilitating placement of an | 2015-04-02 |
| 20150093715 | VISCOUS MATERIAL CONTAINER WITH EXPANDABLE BEND - Provided herein is a viscous material container that is not likely to form continuous streaks or asperities on the surface of a viscous material discharged from the viscous material container even if the viscous material is highly viscous. A third section of a housing includes a wall having a wall portion that is positioned radially outwardly of a continuous angular portion with respect to a second imaginary center line, and extends along the continuous angular portion. The wall portion is configured to expand radially outward when a dental viscous material pushed out from a discharge port. | 2015-04-02 |
| 20150093716 | PATIENT CONTROLLED DENTAL DEVICE AND METHOD - A device for helping maintain a mouth of a patient in an open position during a dental procedure may include a tooth engaging portion including at least one groove for accepting at least one lower tooth of the patient's lower jaw, an extension portion that extends away from the tooth engaging portion, and a handle that extends down from the extension portion and ends in a caudal end. The caudal end of the handle and the groove of the tooth engaging portion lie along a longitudinal axis drawn through a center of the groove. | 2015-04-02 |
| 20150093717 | DEVICES AND METHODS FOR ENHANCING BONE GROWTH - The present invention is generally related to implants for compensating bone loss in mammalian body, and to devices and methods for replacing or creating facial bone. The present invention relates to devices and methods for implanting an implantable device in a subject's body. The implantable device embodying features of the present invention include a body formed from a rig or matrix having a trabecular meshwork structure or cells with shapes suitable for a particular anatomical area of interest. The device may be a dental implant serving as a platform for placement of dental crowns. | 2015-04-02 |
| 20150093718 | HOUSING FOR DENTAL IMPLANTS - Described herein is a housing that releasably connects a dental prosthetic device, such as a full or partial denture, to a dental implant. The housing is at least partially constructed of a resilient material, at least providing the denture with machinability relative to prior art metal housings. A method of manufacturing a housing for a dental implant and a method of retrofitting a housing for a dental implant are described. | 2015-04-02 |
| 20150093719 | METHOD OF MANUFACTURING AN ARTICLE - A method of manufacturing an article including taking an article in an initial state formed using an additive manufacturing process, the article including at least one set of mounting features; performing a second manufacturing process to transform the article into a second state, which includes mounting, via the at least one set of mounting features, the article in a holding device of a machine for operating on the article, wherein the position and orientation of the article in three linear and three rotational degrees of freedom within the machine operating volume is known and defined by virtue of the interaction of the mounting features with the holding device, and processing at least one feature on the article. The at least one mounting feature includes kinematic mount features which engage with corresponding kinematic mount features on the holding device of the machine. | 2015-04-02 |
| 20150093720 | METHOD OF MANUFACTURING AN ARTICLE - A method of manufacturing an article, including taking an article formed in an initial state via an additive manufacturing process and performing a second manufacturing process to transform the article into a second state, which includes mounting the article in a holding device, processing at least one first feature on the article, which includes processing at least one set of mounting features on the article, re-mounting the article via the at least one set of mounting features, and then processing at least one second feature on the article. | 2015-04-02 |
| 20150093721 | DENTAL BLANK TO BE MACHINED, METAL POWDER FOR POWDER METALLURGY, DENTAL METAL FRAME FOR PORCELAIN BONDING, AND DENTAL PROSTHESIS - A dental blank is provided for yielding a metal frame having a desired shape according to a dental CAD/CAM system and a machining process. The dental blank is formed from a metal powder sintered body and contains Co as a main component, Cr in a proportion of 26% by mass or more and 35% by mass or less, Mo in a proportion of 5% by mass or more and 12% by mass or less, and Si in a proportion of 0.5% by mass or more and 1.0% by mass or less. Further, part of the Si is silicon oxide, and the ratio of the silicon oxide to the total amount of Si is preferably 10% by mass or more and 90% by mass or less. | 2015-04-02 |
| 20150093722 | VEHICLE COMPARISON SYSTEM - A system for comparing energy usage of different vehicle platforms is provided. The system may include a processor to execute routines stored in a memory device. Further, in one embodiment the routines include routines configured to receive selection of a driving style by a user and to select a virtual test drive based on the received selection. Also, the routines may include routines configured to output the selected virtual test drive and to output a comparison of multiple vehicles having different characteristics based on the selected virtual test drive. Other systems, methods, and manufactures are also disclosed. | 2015-04-02 |
| 20150093723 | TRACING FIGURES FROM A DISPLAY OF AN ELECTRONIC DEVICE - A manufacture for tracing figures from a display of an electronic device includes a sheet of transparent or semitransparent material having a shape corresponding to the electronic device or the display, and first and second sides. The first and second sides include a tracing area in which a figure displayed on the display is visible in the tracing area through the transparent or semitransparent material. The manufacture for tracing figures from a display of an electronic device also includes an adhesive applied to a portion of the second side of the sheet for the manufacture to adhere to the electronic device or the display such that the figure displayed on the display of the electronic device is visible in the tracing area through the transparent or semitransparent material such that a user may trace the figure on the tracing area by marking the first side with a writing device. | 2015-04-02 |
| 20150093724 | SYSTEM FOR THE IDENTIFICATION AND SELECTION OF THREAD COLOR FOR USE IN THE MACHINE EMBROIDERY OF FABRICS - A system for the determination of thread color includes a fabric having a surface thereon, a digitized embroidery chart stitched on the fabric so as to form a fabric chart, and a recording chart that corresponds to the fabric chart. The fabric has a solid color or multi-color pattern thereon. The fabric chart includes multiple colors in a row or in a column and multiple stitch types in another row or in another column. The fabric chart includes indicia formed thereon associated with the rows or with the columns. The recording chart also includes a plurality of rows and a plurality of columns, along with an alphanumeric character corresponding to the indicia on the fabric chart. | 2015-04-02 |
| 20150093725 | DIET ADHERENCE SYSTEM - A system and method for providing dietary guidance is provided. The method includes receiving a selection of a health program for an individual, the health program including a dietary regimen, measuring the individual's caloric expenditure and change in body composition or body mass during the individual's participation in the health program, determining adherence to the health program based on the measured caloric expenditure or the measured change in body composition or body mass, identifying a modification to the health program, and informing the individual of the modification. The modification can include nutritional supplements, meals or recipes having a nutritional and/or caloric content tailored to assist the individual in meeting his or her health goals. The method can further include predicting an expected change in body composition or body mass based on the health program and based on the individual's gender, age, height, weight, and other factors. | 2015-04-02 |
| 20150093726 | Systems and Methods for Tracking Learning Behavior - Embodiments of the invention provide systems and methods for tracking learning behavior and teaching individuals with Autism Spectrum Disorder and other complex communication needs and learning disabilities. A demonstration of a task having a plurality of steps is provided on a graphical display of a computing device (e.g., a smartphone or tablet computer). The computing device receives an indication of any prompts or reward reminders given to the individual when the individual performs the task. Data is collected and automatically stored regarding the individual's behavior while performing the task. Upon successful completion of the task, a message of praise and/or a reward may be provided to the individual. | 2015-04-02 |
| 20150093727 | VOCABULARY LEARNING SYSTEM AND METHOD - A computerized system and method of teaching vocabulary to a student includes an application that provides words to the student that he or she has previously used in a writing effort. The previously words are utilized to automatically create an individualized vocabulary assignment. The user is instructed to learn the new vocabulary words by breaking the words into their suffixes, prefixes, roots and word origin and/or history. The student is encouraged to create a word history or etymology of the word to understand the history, the language of origin, and the language from which the word is borrowed. The student is then instructed to use the vocabulary word(s) in a sentence. A teacher, instructor or an online tutor may monitor the completion of the various assignments by the student and may also monitor how well the assignments are performed. | 2015-04-02 |
| 20150093728 | Learning Estimation Method and Computer System thereof - A learning estimation method comprises tagging an identification tag on a learning object, recording a learning result corresponding to the learning object when a learner utilizes the learning object to process a learning operation, and obtaining an analytical result for the learner according to the learning result and a learning principle, wherein the identification tag is utilized to recognize characteristics of the learning object. | 2015-04-02 |
| 20150093729 | BIOMETRIC-MUSIC INTERACTION METHODS AND SYSTEMS - A system and method for the automatic, procedural generation of musical content in relation to biometric data. The systems and methods use a user's device, such as a cell phone to capture image data of a body part, and derive a biometric signal from the image data. The biometric signal includes biometric parameters, which are used by a music generation engine to generate music. The music generation can also be based on user-specific data and quality data related to the biometric detection process. | 2015-04-02 |
| 20150093730 | SYSTEMS AND METHODS FOR A SEARCH DRIVEN, VISUAL ATTENTION TASK FOR ENHANCING COGNITION - A method and apparatus for enhancing a cognitive ability of a user is disclosed, which may comprise: conducting, via a user interface display of a user computing device, a training session which may comprise: presenting, via the user interface display of the user computing device, a plurality of objects having at least two identifying parameters, at least two of the plurality of objects having the same at least two identifying parameters forming at least one group of objects having the same at least two identifying parameters and at least one of the objects having at least one unique identifying parameter thereby not duplicating the identifying parameters of the at least two objects in the at least one group of objects; and allowing the user, via the user interface display of the user computing device, to select an object as a proposed unique object. | 2015-04-02 |
| 20150093731 | NATURAL ORIENTATION INDUCTION TOOL APPARATUS AND METHOD - An apparatus for training learning disabled subjects, such as autistic children, induces sound waves into a body of a user through two paths, one heard by the ears through air and the other through a liquid or solid in contact with tissues, such as skin and skeleton on the back of a user, below the collar and centered across the vertical axis of the spine. Two transducers produce waves in the audible sound spectrum, repeat persistently, and provide a tone about a location on which the subject may focus attention. A controller and actuator adhered to the skin by an adhesive gel pad against the back of a wearer. The sound, repeating (after a selected delay), decaying, and seeming to originate above and behind the head of a wearer is a waveform becomes a focus; effective to orient a subject, who lacks natural, self-orientation. | 2015-04-02 |
| 20150093732 | System, Apparatus and Method for Teaching Skiing, Snowboarding, and the Like - A method of instructing an individual to ski includes attaching at least a portion of a bottom surface of a first apparatus to at least a portion of a top surface of a left ski. A top surface of the first apparatus may include indicia that instructs the individual how to maneuver the ski when moving downhill. The method may further include attaching at least a portion of a bottom surface of a second apparatus to at least a portion of a top surface of a right ski. A top surface of the second apparatus may include indicia that instructs the individual how to maneuver the ski when moving downhill. The indicia of the second apparatus may be presented in a different layout than the indicia of the first apparatus. | 2015-04-02 |
| 20150093733 | SOFTWARE PRODUCT USING GAMING PROTOCOLS AND TECHNOLOGY TO HELP PEOPLE DEAL WITH CHRONIC CONDITIONS - A software product using gaming protocols and technology to help people deal with chronic conditions is described herein comprising four modules. The first module presents a therapeutic component to teach condition management skills. The second module presents a query component to assess various conditions. The third module presents an activities component to determine progress towards learning condition management skills. The fourth module presents a progression module to track that progress. Progress reports detailing the user's progress may be provided. | 2015-04-02 |
| 20150093734 | SURGICAL ASSISTANCE USING PHYSICAL MODEL OF PATIENT TISSUE - A method for assisting with a surgical procedure upon a native patient tissue using a physical model of the native patient tissue includes providing a three-dimensional physical model of a patient tissue. At least one surgical action is performed upon the physical model. The at least one surgical action performed upon the physical model is recorded. A planned surgical itinerary including the at least one recorded action performed upon the physical model is produced. The surgical actions of the planned surgical itinerary are performed upon at least one of the native patient tissue and a three-dimensional physical model of a patient tissue. Adherence of the performed surgical actions to the planned surgical itinerary is monitored. | 2015-04-02 |
| 20150093735 | Scientific Instrument Trainer - A training system in which some parts of an instrument are virtualized while other parts are physical. Typically, those parts that are physical are those whose use requires a minimum level of user technique to obtain optimum results. An example of a physical component is a sample injection syringe. Those parts of an instrument that are virtualized are those whose operations are independent of user technique or for which user technique is largely the same in virtualized or physical forms. Examples of virtualized components may include a start button, a detector or a heater. | 2015-04-02 |
| 20150093736 | SYSTEM AND METHOD FOR MANAGING PEDAGOGICAL CONTENT - A system and method for managing pedagogical content are provided. A system and method may capture a screenshot of a presentation of educational or pedagogical content and convert the captured screenshot to an image. A system and method may receive comments from a student and include the comments and image in a pedagogical element, which may be stored in the student's account and may be submitted to a teacher for review, evaluation or assessment A system and method may receive an assessment from a teacher and may include the assessment in the pedagogical element to produce a revised pedagogical element, which may be presented to the student. A system and method may provide a snapshot tool as a Flash library included in a source code of educational content. | 2015-04-02 |
| 20150093737 | APPARATUS AND METHOD FOR AUTOMATIC SCORING - An automatic scoring apparatus includes: an automatic scoring unit to receive scoring target data, apply a corresponding scoring model per each of evaluation regions, and automatically calculate a score per each of the evaluation regions with respect to the received scoring target data based on the applied corresponding scoring model; and a score tuning unit to tune the calculated score per each of the evaluation regions using a corresponding correlation model between the evaluation regions. | 2015-04-02 |
| 20150093738 | Administration And Monitoring Of Nitric Oxide In Ex Vivo Fluids - Described are systems and methods for monitoring administration of nitric oxide (NO) to ex vivo fluids. Examples of such fluids include blood in extracorporeal membrane oxygenation (ECMO) circuits or perfusion fluids used for preserving ex vivo organs prior to transplanting in a recipient. The systems and methods described herein provide for administering nitric oxide to the fluid, monitoring nitric oxide or a nitric oxide marker in the fluid, and adjusting the nitric oxide administration. | 2015-04-02 |
| 20150093739 | SYSTEMS AND METHODS FOR PROCESSING COMPLEX BIOLOGICAL MATERIALS - Method and systems, for processing biological material, that contain a biological material in a vessel; add an aggregating agent to the material in the vessel and allow the material to separate into two or more distinct submaterials; extract one or more of the submaterials from the vessel; automatically transport one or more of the submaterials remaining in the vessel to a filtration device; and collect a resulting target retentate into a target retentate receptacle. | 2015-04-02 |
| 20150093740 | INDEPENDENT PORTS IN AUTOMATED BIOREACTOR SYSTEM - A totipotent plant tissue multiplication system can include a sterile enclosure and a bioreactor in the sterile enclosure. The bioreactor can include a number of ports. A sensor can be inserted into a first port. A matter insertion system can input matter into the bioreactor via tubing configured to be connected to a second port. The sensor can be removed from the first port during operation of the matter insertion system. The tubing can be disconnected from the second port during operating of the sensor and the culture transfer system. | 2015-04-02 |
| 20150093741 | GAS CONTROL IN AUTOMATED BIOREACTOR SYSTEM - A totipotent plant tissue multiplication system can include a plurality of bioreactors, an agitator to agitate culture in the bioreactors, and a gas source and control system. The gas source and control system can include a dissolved gas sensor in each of the bioreactors, gas sources, a manifold connected to each of the gas sources, and valves connected to the manifold. Each of the valves can be connected to one of the bioreactors. A controller can open the valves and control amounts of gas released from the gas sources into the manifold based on signals received from the dissolved gas sensors in each of the bioreactors. | 2015-04-02 |
| 20150093742 | ANTIBODIES FOR ONCOGENIC STRAINS OF HPV AND METHODS OF THEIR USE - The subject invention provides antibodies, including polyclonal and monoclonal antibodies, that bind to E6 proteins from at least three oncogenic strains of HPV. In general, the antibodies bind to amino acids motifs that are conserved between the E6 proteins of different HPV strains, particularly HPV strains 16 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing the subject methods and containing the subject antibodies are also provided. | 2015-04-02 |
| 20150093743 | ON-DEMAND PARTICLE DISPENSING SYSTEM - Systems, including apparatus and methods, for the microfluidic manipulation, dispensing, and/or sorting of particles, such as cells and/or beads. | 2015-04-02 |
| 20150093744 | CAPTURE OF HUMAN NOROVIRUS FROM CLINICAL ENVIRONMENTAL AND FOOD SAMPLES AND MEASUREMENT OF INFECTIVITY - The present invention relates to human noroviruses. | 2015-04-02 |
| 20150093745 | OPTOELECTRONIC DETECTION SYSTEM - The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal. | 2015-04-02 |
| 20150093746 | Virus Causing Respiratory Tract Illness in Susceptible Mammals - The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus | 2015-04-02 |
| 20150093747 | MAIZE EVENT DP-004114-3 AND METHODS FOR DETECTION THEREOF - The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided. | 2015-04-02 |
| 20150093748 | METHOD AND PRIMERS FOR THE DETECTION OF MICROCYSTIN-PRODUCING TOXIC CYANOBACTERIA - The present invention provides a method for detecting the presence of microcystin-producing toxic | 2015-04-02 |
| 20150093749 | REAL-TIME PCR DETECTION OF STREPTOCOCCUS PYOGENES - The present invention relates to assays, diagnostic kits and methods for real-time PCR detection of | 2015-04-02 |
| 20150093750 | MAGNETICALLY ASSISTED PROCESSING OF A MEDIUM - The invention relates to a processing device ( | 2015-04-02 |
| 20150093751 | PRIMERS FOR DIAGNOSING AVELLINO CORNEAL DYSTROPHY - The present invention relates to a real-time PCR primer pair and probe for diagnosing Avellino corneal dystrophy, and more particularly to a real-time PCR primer pair and probe for diagnosing Avellino corneal dystrophy, which can accurately diagnose the presence or absence of a mutation in exon 4 of BIGH3 gene, which is responsible for Avellino corneal dystrophy. The use of the primer pair and probe according to the invention can diagnose Avellino corneal dystrophy in a more rapid and accurate manner than a conventional method that uses a DNA chip or PCR. | 2015-04-02 |
| 20150093752 | Conversion of alpha-hydroxyalkylated residues in biomolecules using methyltransferases - The present invention relates to targeted conversion of alpha-hydroxyalkylated residues in biomolecules in the presence of a directing methyltransferase, namely to targeted removal of the alpha-hydroxyalkyl moieties to give unmodified residues, or targeted derivatization of the alpha-hydroxyalkyl groups by covalent coupling of non-cofactor compounds represented by formula HQ-LX, wherein X represents a functional group or a reporter group attached via a linker moiety L, and QH is selected from HS—, HSe—, HO—H | 2015-04-02 |
| 20150093753 | METHODS FOR QUANTITATIVE AMPLIFICATION AND DETECTION OVER A WIDE DYNAMIC RANGE - Disclosed are compositions and methods for making differentiable amplicon species at unequal ratios using a single amplification system in a single vessel. The number of differentiable amplicons and their ratios to one another are chosen to span the required linear dynamic range for the amplification reaction and to accommodate limitations of the measuring system used to determine the amount of amplicon generated. Unequal amounts of distinguishable amplicon species are generated by providing unequal amounts of one or more amplification reaction components (e.g., distinguishable amplification oligomers, natural and unnatural NTP in an NTP mix, or the like). The amount of target nucleic acid present in a test sample is determined using the linear detection range generated from detection of one or more amplicon species having an amount within the dynamic range of detection. | 2015-04-02 |
| 20150093754 | ANALYZER, ANALYZING METHOD, AND TIP CONTAINER - Disclosed is an analyzer comprising: a liquid container mounting section in which a liquid container are set; a container mounting section in which at least one tip container accommodating a plurality of pipette tips is set; a cover detecting section that detects a presence of a cover mounted on the tip container; a dispensing section that equips a pipette tip accommodated in the tip container and dispenses a quantity of liquid from the liquid container to a reaction container via the equipped pipette tip; a detecting section that interrogate a property of the liquid; and a controller programmed to prohibit a process of equipping the pipette tip by the dispensing section when the cover on the tip container is detected, and permits the process when no cover is detected. | 2015-04-02 |
| 20150093755 | METHOD FOR ASSESSING JUICE/CIDER QUALITY AND/OR SAFETY - A novel method for isolating DNA from juices and ciders is described. This method is low cost and yield large quantities of highly purified DNA even though one uses a small quantity of juice or cider. A method for determining if a juice or cider is safe to consume and/or the quality of the juice or cider are also described. For these methods, one can perform qPCR on the DNA which can be obtained using the disclosed method or any other prior art method, and comparing the amount of DNA from microorganisms is present in the juice and/or cider to determine the safety and/or quality of the juice and/or cider. These methods work even if the liquid was pasteurized. | 2015-04-02 |
| 20150093756 | Thermophilic Helicase Dependent Amplification Technology With Endpoint Homogenous Fluorescent Detection - Disclosed herein are methods of amplifying a target nucleic acid in a helicase-dependent reaction. Also disclosed are methods of amplifying and detecting a target nucleic acid in a helicase-dependent reaction as well as modified detection labels to assist in the detection. | 2015-04-02 |
| 20150093757 | METHODS. APPARATUS AND SYSTEMS FOR DETECTION OF TOTAL PROTEIN USINGCAPILLARY ELECTROPHORESIS - Capillary electrophoresis methods for determining the relative amount of protein in a sample comprising a population of proteins are provided. The methods comprise charge and/or size separation of a target protein or a plurality of target proteins present in a sample, for example a biological sample, by capillary electrophoresis in a separation matrix comprising a haloalkane compound, and downstream detection and quantification of the total amount of protein in the sample. Optionally, the method further comprises detection and quantification of one or more specific target proteins in the sample. Systems for carrying out the methods are also provided. | 2015-04-02 |
| 20150093758 | PSA CAPTURE AGENTS, COMPOSITIONS, METHODS AND PREPARATION THEREOF - Disclosed herein are novel synthetic prostate specific antigen (PSA)-targeted capture agents that specifically bind PSA. In certain embodiments, these PSA capture agents are biligand or triligand capture agents containing two or three target-binding moieties, respectively. | 2015-04-02 |
| 20150093759 | COMPOSITIONS AND METHODS FOR DETECTING NITRATION OF PKG-1a AND METHODS OF USE THEREOF - Antibodies for detecting nitration of nitrotyrosine 247 PKG-1α and antibodies for detecting nitrotyrosine 425 of PKG-1α are disclosed. Methods of detecting nitrotyrosine 247 PKG-1α and nitrotyrosine 425 of PKG-1α, and uses thereof are also disclosed for identification and diagnosis or phenotypes, pathologies, diseases and disorders associated with protein nitration of PKG-1α are also disclosed. In a preferred embodiment, one or more of the disclosed antibodies is used in the disclosed methods. | 2015-04-02 |
| 20150093760 | CARTRIDGE AND SYSTEM FOR DETECTING OF GLYCATED PROTEIN IN SAMPLE AND METHOD OF DETECTING GLYCATED PROTEIN USING THE SAME - A cartridge for measuring a concentration of a glycated protein in a wide measurement range, a system for measuring a glycated protein, and a method of measuring a glycated protein using same. | 2015-04-02 |
| 20150093761 | Differentiation and amplification method for inducing human neuralstem/progenitor cells to differentiate into oligodendrocyte progenitor cells andapplication thereof - A Method for inducing human neural stem/progenitor cells to differentiate into oligodendrocyte progenitor cells and application thereof comprises following steps of: pre-treating neural stem cells derived from different resources in pre-treatment medium including bFGF and EGF for culturing; and inducing neural stem cells after pre-treating with inducing medium including PDGF-AA, bFGF and NT3, so as to differentiate into oligodendrocyte progenitor cells (OPCs). Main markers of the OPCs obtained by the method, such as NG2, O4, A2B5 and PDGFR, have a positive rate of 80˜90%. The OPCs obtained thereby is capable of proliferating steadily in the OPCs inducing medium for at least 10 generations and simultaneously maintaining biological characteristics thereof unchanged. The OPCs induced by the present invention can be applied in treating myelin-associated diseases or researching on drug screening. | 2015-04-02 |
| 20150093762 | HEPATIC STELLATE CELL PRECURSORS AND METHODS OF ISOLATING SAME - The present invention relates to precursor cells to hepatic stellate cells, compositions comprising same and methods of isolating same. The surface antigenic profile of the precursors is MHC class Ia negative, ICAM-1 | 2015-04-02 |
| 20150093763 | METHOD FOR DIAGNOSIS OF PULMONARY INVOLVEMENT IN SYSTEMIC SCLEROSIS - A method for the diagnosis and/or therapy control of systemic sclerosis is disclosed wherein soluble CD90 is detected in body fluids. By measuring the concentration of soluble CD90 certain forms of diseases can be differentiated by applying the ex vivo method. | 2015-04-02 |
| 20150093764 | BLOCKING REAGENT COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME - Blocking reagent compositions, as well as methods of making and using the same, are provided. Aspects of the composition include a blocking reagent that binds to the cell surface but does not specifically bind to a targeted first cell surface antigen. Also provided are system and kits that include the compositions. | 2015-04-02 |
| 20150093765 | METHOD OF PROGNOSIS - The present invention relates to the use of soluble CD163 as a prognostic marker for the assessment of the risk for contracting a disorder, in particular for contracting diabetes and/or a liver disorder. The invention also relates to the use of CD163 as a prognostic marker for assessing lifetime expectancy. | 2015-04-02 |
| 20150093766 | DIAGNOSTIC REAGENTS - There is provided a diagnostic reagent useful to determine whether an animal has a tuberculosis infection or has been exposed to a tuberculosis agent, for example a | 2015-04-02 |
| 20150093767 | METHODS FOR DIAGNOSIS AND PROGNOSIS OF EPITHELIAL CANCERS - The present invention is based on the discovery that three proteins, Cystatin B, Chaperonin 10, and Profilin are present in the urine of patients with bladder cancer, a cancer of epithelial origin. Accordingly, the present invention is directed to methods for prognostic evaluation of cancers of epithelial origin and to methods for facilitating diagnosis of cancers of epithelial origin by monitoring the presence of these markers in biological samples. The invention is also directed to markers for therapeutic efficacy. | 2015-04-02 |
| 20150093768 | DETECTION OF PROSTATE AND BLADDER CANCER - The present invention relates to a method for the diagnosis, prognosis, and monitoring of cancer, such as early or late stage prostate cancer and bladder cancer, in a subject by detecting Bcl-2 in a biological sample from the subject, preferably a urine or blood sample. Bcl-2 may be measured using an agent that detects or binds to Bcl-2 protein or an agent that detects or binds to encoding nucleic acids, such as antibodies specifically reactive with Bcl-2 protein or a portion thereof. The invention further relates to kits for carrying out the methods of the invention. The invention further relates to a device for the rapid detection of Bcl-2 in a bodily fluid and methods for rapidly measuring Bcl-2 in a bodily fluid. | 2015-04-02 |
| 20150093769 | METHOD FOR DETERMINING THE CONCENTRATION OF THE ADIPOCYTIC FORM OF THE FATTY ACID BINDING PROTEIN (A-FABP, FABP4, P2) - Products and methods for the research, diagnosis, risk assessment, course monitoring, treatment and prophylaxis of various metabolic disorders and their early forms, concomitant diseases and secondary diseases are provided. Metabolic diseases include, for example, metabolic syndrome, non-insulin-dependent diabetes, (type II diabetes), insulin resistance, obesity (adiposis), in addition to diseases that are associated with disorders of the fatty acid metabolism. Methods may include analysis of the concentration of the adipocytic form of the fatty acid binding protein (A-FABP, FABP 4, P2) in various bodily fluids. | 2015-04-02 |
| 20150093770 | METHOD AND DEVICE FOR THE DETERMINATION OF PLATELET FUNCTION UNDER FLOW CONDITIONS - The invention lies in the area of platelet function diagnostics and relates to a method for the determination of platelet function under flow conditions as well as a device for the implementation of this method. The method is particularly suitable for the determination of the effect of clopidogrel and of other P2Y(12) antagonists with antithrombotic activity as well as the determination of P2Y(1) antagonists with antithrombotic activity. | 2015-04-02 |
| 20150093771 | MICROFLUIDIC ANALYTICAL DEVICE FOR ANALYSIS OF CHEMICAL OR BIOLOGICAL SAMPLES, METHOD AND SYSTEM THEREOF - An analytical device for analysis of chemical or biological samples, a method of using such a device, based on rotation of the device, integrated sample dosing and optical detection, and a system comprising such a device are disclosed. The analytical device comprises a device body having a liquid processing unit. The liquid processing unit comprises a mixing chamber for mixing a sample with a reagent, a sample dosing chamber for delivering a defined volume of the sample to the mixing chamber, and a reagent channel for delivering the reagent to be mixed with the sample, wherein the mixing chamber also serves as a detection chamber. | 2015-04-02 |
| 20150093772 | METHOD FOR EVALUATING COSMETIC - It is an object of the invention to provide a method for evaluating cosmetics that allows development of cosmetics that can contribute to beautiful healthy skin. The object is achieved by a method of evaluating improvement in skin by an applied cosmetic, using as the index the change in stratum corneum thickness during the process of moistening and drying. | 2015-04-02 |
| 20150093773 | METHOD OF INSERTING DNA FRAGMENTS INTO GENOME BY USING MARKER GENE EXPRESSION - Provided is a method of inserting a target sequence into a genome of a cell through positive selection or negative selection based on whether a marker is expressed. | 2015-04-02 |
| 20150093774 | SENSORS AND METHODS FOR CAPTURE, KILLING, AND RELEASE OF BACTERIA - There is provided a renewable sensor for sensing or selectively capturing a targeted bacteria in a fluid. The renewable sensor includes a surface, the surface includes a substrate, a biologically or bacterially non-adhesive feature disposed on or in functional proximity to at least a portion of the substrate; and an adhesive elements disposed on or in functional proximity to the non-adhesive feature, a flow channel in operative contact with the surface; and a detector configured to detect the targeted cell type captured on the surface. Also provided are method for using the sensor and the surface. | 2015-04-02 |
| 20150093775 | SYSTEM AND METHOD FOR ANALYTE SENSING AND MONITORING - An analyte sensing and monitoring system and method is provided that is particularly applicable to monitoring of analytes in cell cultures. The system and method relies on the initial diffusion rates of the analytes from the medium that contains the analytes being measured (e.g., cell culture) into a diffusion chamber that is inserted into the medium, and remote sensing of the analytes using an analyte sensing system that is coupled to the diffusion chamber. | 2015-04-02 |
| 20150093776 | POLYPHENOL, TERPENOID, GLYCOSIDE, AND ALKALOID PRODUCTION BY CROCUS SATIVUS CELL CULTURES - A method for producing metabolites of | 2015-04-02 |
| 20150093777 | METHODS FOR DETERMINING AND/OR MONITORING CONDITIONS OF A THREE DIMENSIONAL CELL CULTURE SYSTEM AND OPTICAL SENSOR DEVICE FOR CONDUCTING SAID METHODS - A method for at least one of determining and monitoring at least one condition of/in a three dimensional cell culture system comprising at least one growth section, the at least one condition being selected from the group consisting of a physiological condition, a vitality, and a metabolism status, the method includes determining the physiological condition using erythrocytes as detectors, determining and/or monitoring the vitality by measuring living cell fluorescent dyes, and determining and/or monitoring the metabolism status by at least one of measuring an autofluorescence of NADH and/or FAD, by determining a NADH/NAD | 2015-04-02 |
| 20150093778 | VIBRIO ASSAY METHODS AND KITS - Methods and kits for detection of bacteria, especially | 2015-04-02 |
| 20150093779 | SYSTEM AND DEVICE FOR CHARACTERIZING CELLS - A diagnostic device includes a microscope configured to obtain image data on a plurality of cells and a computing device. The computing device is configured to receive the image data, identify at least a portion of each of the plurality of cells based on the received image data, determine at least one of a value of a morphological parameter for each identified at least a portion of the plurality of cells or a relative organization among the identified at least a portion of the plurality of cells, and calculate statistics for the plurality of cells based on the at least one of the determined values of the morphological parameter or the determined relative organization, the statistics including information suitable for distinguishing metastatic cells from non-metastatic cells. The diagnostic device further includes an output device configured to output the statistics for diagnosis. | 2015-04-02 |
| 20150093780 | PREPARATION OF THIN TISSUE SECTIONS FOR IMAGING MASS SPECTROMETRY - The invention relates to the preparation of thin tissue sections for mass spectrometric (MALDI) imaging, and proposes a method wherein a microcrystalline layer of the matrix material is produced on the surface of the thin tissue sections, and soluble analyte molecules are transported orthogonally through the thin tissue section to the matrix layer, without substantial lateral diffusion, by means of a solvent flow with alternating or constant direction, and are then deposited in the matrix layer and, if possible, embedded in the matrix crystals. A solvent flow which alternates in direction can be produced by successive, alternating phases of swelling and drying, brought about by periodic changes to the thin tissue section temperature and/or the partial pressures of the solvents. A continuous solvent flow can be generated by applying the thin tissue section onto a porous support which supplies solvent to the rear surface of the thin tissue section. | 2015-04-02 |
| 20150093781 | MICROORGANISM FOR EXPRESSING A HUMAN MEMBRANE PROTEIN - The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced C24-methyltransferase and/or delta22-desaturase activity compared to the wild type. The invention is characterized in that the organism has increased dehydrocholesterol-delta70-reductase activity compared to the wild type. The invention further relates to different uses of such an organism, to a test kit comprising such an organism, and to a membrane extract of such an organism. | 2015-04-02 |
| 20150093782 | COMPOSITIONS AND METHODS FOR REDUCING FUCOSYLATION OF GLYCOPROTEINS IN INSECT CELLS AND METHODS OF USE THEREOF FOR PRODUCTION OF RECOMBINANT GLYCOPROTEINS - Compositions for reducing fucosylation of glycoproteins in insect cells are provided. Also disclosed are methods of use of such compositions for the production of recombinant humanized proteins. | 2015-04-02 |
| 20150093783 | HUMANIZED ANTIBODIES TO CA215 - Provided herein are humanized forms of murine RP215 monoclonal antibodies and methods of using the same. These humanized RP215 monoclonal antibodies were characterized in terms of their respective affinity and specificity to the corresponding tumor-associated antigen, CA215, and shown to be comparable to those of murine RP215. | 2015-04-02 |
| 20150093784 | Cell Culture Improvements - The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. | 2015-04-02 |
| 20150093785 | SYSTEM AND METHOD FOR PROCESSING BIOLOGICAL MATERIAL - The invention provides apparatus and processes for cultivating algae. | 2015-04-02 |
| 20150093786 | Laboratory apparatus and method of using a laboratory apparatus - The invention is related to a laboratory apparatus and method for the automated processing of liquid samples, in particular for the program controlled handling of liquid samples, having an electronic control device, which is adapted to process a program code for the program controlled processing of fluid samples, at least one processing space for receiving the fluid samples to be processed, at least one electronically controllable sample processing device for performing at least one program controlled process step on at least one sample, which is arranged in the processing space, at least one electronically controllable decontamination device for cleaning at least a part of the processing space, wherein the decontamination device is configured to be controlled by the control device and the control device is configured to digitally control the decontamination device. | 2015-04-02 |
| 20150093787 | COMPOSITIONS AND METHODS FOR USE IN RECOMBINATIONAL CLONING OF NUCLEIC ACIDS - The present invention relates generally to compositions and methods for use in recombinational cloning of nucleic acid molecules. In particular, the invention relates to nucleic acid molecules encoding one or more recombination sites or portions thereof, to nucleic acid molecules comprising one or more of these recombination site nucleotide sequences and optionally comprising one or more additional physical or functional nucleotide sequences. The invention also relates to vectors comprising the nucleic acid molecules of the invention, to host cells comprising the vectors or nucleic acid molecules of the invention, to methods of producing polypeptides using the nucleic acid molecules of the invention, and to polypeptides encoded by these nucleic acid molecules or produced by the methods of the invention. The invention also relates to antibodies that bind to one or more polypeptides of the invention or epitopes thereof. The invention also relates to the use of these compositions in methods for recombinational cloning of nucleic acids, in vitro and in vivo, to provide chimeric DNA molecules that have particular characteristics and/or DNA segments. | 2015-04-02 |
| 20150093788 | METHODS AND REAGENTS FOR MOLECULAR CLONING - The present invention provides compositions, methods, and kits for covalently linking nucleic acid molecules. The methods include a strand invasion step, and the compositions and kits are useful for performing such methods. For example, a method of covalently linking double stranded (ds) nucleic acid molecules can include contacting a first ds nucleic acid molecule, which has a topoisomerase linked to a 3′ terminus of one end and has a single stranded 5′ overhang at the same end, with a second ds nucleic acid molecule having a blunt end, such that the 5′ overhang can hybridize to a complementary sequence of the blunt end of the second nucleic acid molecule, and the topoisomerase can covalently link the ds nucleic acid molecules. The methods are simpler and more efficient than previous methods for covalently linking nucleic acid sequences, and the compositions and kits facilitate practicing the methods, including methods of directionally linking two or more ds nucleic acid molecules. | 2015-04-02 |
| 20150093789 | METHOD FOR ENHANCING OIL PRODUCTION FROM GRAIN - A process for increasing oil yield from grain that includes passing a grain-based liquid stream of an alcohol production process through a cavitation apparatus to apply cavitational energy to the grain-based liquid stream, wherein the cavitational energy is applied to the grain-based liquid stream prior to a distillation phase of the alcohol production process. | 2015-04-02 |
| 20150093790 | THERMOSTABLE C. BESCII ENZYMES - The disclosure provides thermostable enzymes isolated from | 2015-04-02 |
| 20150093791 | THERMOCELLULASES FOR LIGNOCELLULOSIC DEGRADATION - Thermostable cellulase enzyme systems comprising at least one each of a thermostable endoglucanase, an exo-processive-endoglucanase, and a β-glucosidase carry out the complete, coordinated hydrolysis of crystalline cellulose to monomeric glucose. | 2015-04-02 |
| 20150093792 | Polypeptides Having Glucoamylase Activity and Polynucleotides Encoding Same - The present invention relates to isolated polypeptides having glucoamylase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 2015-04-02 |
| 20150093793 | NOVEL METHOD FOR PRODUCING METABOLITES FROM OMEPRAZOLE USING BACTERIAL CYTOCHROME P450, AND COMPOSITION FOR SAME - The present invention relates to a novel method for producing metabolites from omeprazole using bacterial cytochrome P450, and a composition therefor, and more specifically, to a composition and a kit for producing a 5′-hydroxyl product from omeprazole, containing bacterial cytochrome P450 BM3 (CYP102A1) or mutants thereof, and to a method for producing the same. The composition, the kit, and the method are capable of economically and highly efficiently mass-producing the 5′-hydroxyl product from the omeprazole, and thus will significantly contribute to development of a novel drug using metabolites from the omeprazole. | 2015-04-02 |
| 20150093794 | CELLULAR PRODUCTION OF GLUCARIC ACID - The invention relates to the production of glucuronic and glucaric acid in cells through recombinant expression of myo-inositol 1-phosphate synthase, myo-inositol oxygenase and uronate dehydrogenase. Cloning and characterization of the gene encoding uronate dehydrogenase is also disclosed. | 2015-04-02 |
| 20150093795 | Cutinase Variants and Polynucleotides Encoding Same - The present invention relates tocutinasevariants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. | 2015-04-02 |
| 20150093796 | CLOSTRIDIUM ACETOBUTYLICUM AND APPLICATION THEREOF - The present invention provides | 2015-04-02 |
| 20150093797 | PRODUCTION OF ACETYL-COENZYME A DERIVED ISOPRENOIDS - Provided herein are compositions and methods for the heterologous production of acetyl-CoA-derived isoprenoids in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an acetaldehyde dehydrogenase, acetylating (ADA, E.C. 1.2.1.10) and an MEV pathway comprising an NADH-using HMG-CoA reductase. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an ADA and an MEV pathway comprising an acetoacetyl-CoA synthase. In some embodiments, the genetically modified host cell further comprises one or more heterologous nucleotide sequences encoding a phosphoketolase and a phosphotransacetylase. In some embodiments, the genetically modified host cell further comprises a functional disruption of the native PDH-bypass. The compositions and methods described herein provide an energy-efficient yet redox balanced route for the heterologous production of acetyl-CoA-derived isoprenoids. | 2015-04-02 |
| 20150093798 | MICROORGANISM CAPABLE OF PRODUCING 1,4-BUTANEDIOL AND METHOD OF PRODUCING 1,4-BUTANEDIOL USING THE SAME - A microorganism capable of producing 1,4-butanediol and a method of producing 1,4-butanediol using the same. | 2015-04-02 |
| 20150093799 | HISTIDYL-TRNA SYNTHETASES FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES - The present invention relates generally to compositions and methods comprising histidyl-tRNA synthetase polypeptides or other specific blocking agents for the treatment autoimmune diseases and other inflammatory diseases, including those related to Jo-1 antibodies. | 2015-04-02 |
| 20150093800 | METHOD FOR CHROMATOGRAPHY REUSE - The present invention provides methods for cleaning or regenerating a chromatography materiel for reuse. The methods of the invention can be used for cleaning or regenerating chromatography columns for reuse in the large-scale manufacture of multiple polypeptide products. | 2015-04-02 |
| 20150093801 | Solubilized Phospholipids for Stabilizing Nucleic Acid Polymerases - Compositions and methods are provided that relate to solubilized phospholipids and their use in stabilizing nucleic acid polymerases. For example, a phospholipid with a tail containing at least 8 carbons can be solubilized in the presence of an amphipathic molecule. | 2015-04-02 |
| 20150093802 | ZINC FINGER NUCLEASE FOR THE CFTR GENE AND METHODS OF USE THEREOF - The present invention provides new zinc finger proteins and zinc finger nuclease (ZFNs) that find particular using in repairing the cystic fibrosis transmembrane conductance regulator (CFTR) gene. | 2015-04-02 |
| 20150093803 | NITRILE HYDRATASE VARIANT - A nitrile hydratase variant of the present invention comprises substitution of at least one amino acid with another amino acid to improve two or more properties of nitrile hydratase by substitution of one amino acid. | 2015-04-02 |
| 20150093804 | METHOD FOR PREPARING VIRUS-LIKE PARTICLE AND RECOMBINANT BACULOVIRUS USED THEREIN - A recombinant baculovirus is provided for preparing picornavirus virus-like particles (VLP), wherein Chitinase A (ChiA) and Cathepsin V (v-cath) genes of the recombinant baculovirus are functionally disrupted and the recombinant baculovirus includes a picornavirus capsid protein gene under control of a strong promoter, and includes a protease gene configured for encoding a protease for hydrolyzing the capsid protein under control of a weak promoter. The recombinant baculovirus of the present invention may adopt High Five or Sf-9 cells for manufacturing enterovirus virus-like particles with improved stability and higher yields in comparison with the conventional arts. A method for preparing virus like particles is also herein provided. | 2015-04-02 |
| 20150093805 | POLYPEPTIDES HAVING ALPHA-AMYLASE AND GRANULAR STARCH HYDROLYZING ACTIVITY - The present invention relates to a polypeptide having alpha-amylase activity obtained from a strain of | 2015-04-02 |
| 20150093806 | Method for Photoculturing and Harvesting Microalgae - The present invention relates to a method for photoculturing and harvesting microalgae, and more particularly to a method for photoculturing and harvesting microalgae, in which a light emitting diode (LED) is used as a light source to increase the efficiency with which microalgae are cultured, and the cultured microalgae are harvested using a natural polymer flocculant and air microbubbles so that the operating cost is reduced and the range of application of microalgae is expanded, and also a semi-continuous culture method is applied so that the maximum concentration of microalgae can be produced again within a short time, even though the amount of microalgae harvested is small. | 2015-04-02 |
| 20150093807 | METHOD FOR CONTROLLING DEGRADATION OF BIODEGRADABLE POLYESTER AND DEGRADATION-CONTROLLED BIODEGRADABLE POLYESTER - The present disclosure relates to a method for controlling degradation of biodegradable polyester. To be specific, biodegradation caused by a depolymerase is suppressed by capping a carboxyl terminal in biodegradable polyhydroxyalkanoate (PHA) having the carboxyl group at one terminal or its copolymer, and, thus, it is possible to easily suppress or control degradation depending on a capping ratio of the carboxyl group. | 2015-04-02 |
