14th week of 2015 patent applcation highlights part 38 |
Patent application number | Title | Published |
20150093407 | TUBERCULOSIS TB VACCINE TO PREVENT REACTIVATION - The present invention discloses a vaccine or immunogenic composition that can be administered to latently infected individuals to prevent reactivation of latent tuberculosis infection caused by species of the tuberculosis complex microorganisms ( | 2015-04-02 |
20150093408 | Lyme disease vaccine, genetic construct, recombinant protein, method for designing genetic construct, method for producing vaccine, method for producing recombinant proteins, use of recombinant proteins in the production of Lyme disease vaccine - The present invention relates to a Lyme disease vaccine, a genetic construct, recombinant protein, method for genetic construct design, method for vaccine delivery, method for recombinant proteins delivery, use of recombinant proteins in the production of Lyme disease vaccine. In particular, the method concerns the use of TROSPA and TROSPA-Salp15 recombinant proteins derived from castor bean tick ( | 2015-04-02 |
20150093409 | Topical Compositions Comprising Fermented Extracts of Traditional Chinese Medicinal (TCM) Ingredients, and Methods of Making and Using Same - The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products. | 2015-04-02 |
20150093410 | Stimulation of An Immune Response By Cationic Lipids - The present invention provides compositions and methods for stimulating an immune response using cationic lipids alone or in combination with antigens. | 2015-04-02 |
20150093411 | Chimeric Multivalent Polysaccharide Conjugate Vaccines - The present invention provides multivalent chimeric conjugate vaccine molecule and methods of using the conjugate to immunize subjects against bacterial infections. A conjugate molecule of the invention comprises multiple bacterial capsular polysaccharides linked to a carrier protein. Accordingly, the conjugate molecule provides immune protection against multiple types of bacteria in a single vaccines. In particular, conjugate molecules of the invention are used to prevent or attenuate Group B | 2015-04-02 |
20150093412 | USE OF SACCHARIDES CROSS-REACTIVE WITH BACILLUS ANTHRACIS SPORE GLYCOPROTEIN AS A VACCINE AGAINST ANTHRAX - Provided are immunogenic compositions and methods for eliciting an immune response against | 2015-04-02 |
20150093413 | NUCLEIC ACID COMPRISING OR CODING FOR A HISTONE STEM-LOOP AND A POLY(A) SEQUENCE OR A POLYADENYLATION SIGNAL FOR INCREASING THE EXPRESSION OF AN ENCODED PATHOGENIC ANTIGEN - The present invention relates to a nucleic acid sequence, comprising or coding for a coding region, encoding at least one peptide or protein comprising a pathogenic antigen or a fragment, variant or derivative thereof, at least one histone stem-loop and a poly(A) sequence or a polyadenylation signal. Furthermore the present invention provides the use of the nucleic acid for increasing the expression of said encoded peptide or protein. It also discloses its use for the preparation of a pharmaceutical composition, especially a vaccine, e.g. for use in the treatment of infectious diseases. The present invention further describes a method for increasing the expression of a peptide or protein comprising a pathogenic antigen or a fragment, variant or derivative thereof, using the nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal. | 2015-04-02 |
20150093414 | MODIFIED ANTIGENS - Modified Rv3616c proteins and their use as medicaments, particularly for the prevention of reactivation of tuberculosis. | 2015-04-02 |
20150093415 | ANTIGEN COMPOSITION, PREPARATION METHOD AND USE THEREOF, AND TUMOR VACCINE - The present invention provides a preparation method of an antigen composition. The preparation method comprises the following steps: (1) obtaining a tumor antigen protein; (2) making the tumor antigen protein into contact with an immature dendritic cell; (3) inducing the immature dendritic cell in contact with the tumor antigen into a mature dendritic cell; and (4) separating a cell vesicle of the mature dendritic cell. The present invention further provides an antigen composition obtained through the preparation method and the application thereof in preparing a tumor vaccine. | 2015-04-02 |
20150093416 | AUTOLOGOUS TUMOR VACCINES AND METHODS - Autologous anti-cancer vaccines and methods of manufacture and treatment are provided, including expansion of individual patient-derived tumor cells in an immune-compromised animal(s) to attain, quantitatively and qualitatively, sufficient material for efficacious vaccine production and utilization, to elicit an immune response against micrometastases and/or recurrence in the individual patient following tumor excision. | 2015-04-02 |
20150093417 | Compositions And Methods For Inhibiting Expression Of CD45 Gene - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the CD45 gene. | 2015-04-02 |
20150093418 | EYE SWAB - In accordance with the invention, with an eye swab for cleaning eyes of vertebrate animals, for example dog's eyes, is provided. The eye swab consists of a gel-like putty, wherein the gel-like putty is held together from a reversibly bonded, three-dimensional network formed of at least one natural or synthetic polymer, at least one cross-linking agent and glycerol. | 2015-04-02 |
20150093419 | ABSORPTION ENHANCERS SUCH AS E.G. BHT, BHA OR PROPYL GALLATE - The invention provides a pharmaceutical composition comprising a mixture of (a) an active macromolecular principle, and (b) an aromatic alcohol absorption enhancer chosen from butylated hydroxy toluene, butylated hydroxy anisole and analogues and derivatives thereof, wherein the aromatic alcohol absorption enhancer is present in an amount by weight greater than or equal to that of the active macromolecular principle, and further comprises a pharmaceutical composition comprising a mixture of (a) an active macromolecular principle, (b) an aromatic alcohol absorption enhancer chosen from propyl gallate, butylated hydroxy toluene, butylated hydroxy anisole and analogues and derivatives thereof, wherein the aromatic alcohol absorption enhancer is present in an amount by weight greater than or equal to that of the active macromolecular principle, and (c) a solubilisation aid capable of increasing the solubility of the aromatic alcohol absorption enhancer in aqueous media. | 2015-04-02 |
20150093420 | Hair Conditioning Compositions Comprising Low Viscosity Emulsified Silicone Polymers - Embodiments of a hair conditioning composition include a silicone polymer comprising one or more quaternary groups, at least one silicone block comprising greater than 200 siloxane units, at least one polyalkylene oxide structural unit, and at least one terminal ester group. The silicone polymer has a viscosity of up to 100,000 mPa·s. The silicone polymer is a pre-emulsified dispersion with a particle size of less than about 1 micron. The hair conditioning composition includes a gel matrix including a cationic surfactant, a high melting point fatty compound, and an aqueous carrier. | 2015-04-02 |
20150093421 | Hair Compositions Comprising Low Viscosity Silicone Polymers - Embodiments of a hair conditioning composition include a silicone polymer comprising one or more quaternary groups, at least one silicone block comprising greater than 200 siloxane units, at least one polyalkylene oxide structural unit, and at least one terminal ester group. The silicone polymer has a viscosity of up to 100,000 mPa·s. The hair conditioning composition also includes a polymeric thickener. | 2015-04-02 |
20150093422 | Methods and Compositions for Preventing or Reducing Frizzy Appearance of Hair - Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified aluminum oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle. | 2015-04-02 |
20150093423 | CERAGENIN PARTICULATE MATERIALS AND METHODS FOR MAKING SAME - Particulate ceragenin materials may be manufactured by (i) providing a ceragenin feed material comprised of ceragenin molecules, each having a sterol backbone and a plurality cationic groups attached thereto; (ii) fracturing the ceragenin feed material in a milling apparatus to produce a ceragenin particulate material having a particle size distribution with a median particle size in a range from 5 nm to 20 μm; and (iii) during fracturing, maintaining the ceragenin feed with a moisture content of less than or equal to 10% by weight. | 2015-04-02 |
20150093424 | Antibacterial Surfactant/Microgel Formulations, Methods of Making and Methods of Using the Same - Formulations having, as active agents, at least one quaternized polymeric microgel and at least one surfactant, methods of making, and methods of using are described. | 2015-04-02 |
20150093425 | ENVIRONMENTALLY PREFERRED ANTIMICROBIAL COMPOSITIONS - Provided are antimicrobial compositions that include peracid compositions. The peracid compositions have increased shelf life and storage stability. The antimicrobial compositions can be formulated into a hard surface disinfectant composition that includes a hydrogen peroxide generator, a peracetic acid catalyst, a slow hydrolyzing acid and optionally a carboxylic acid, where the ratio between the hydrogen peroxide generator and the peracetic acid catalyst is from about 1.5:1 to about 3:1 respectively. | 2015-04-02 |
20150093426 | FOAM FORMULATIONS AND APPARATUS FOR DELIVERY - Foamable formulations of agriculturally active ingredients are provided, as well as methods for using them. The formulations allow improved delivery active ingredients by the ability to deliver high amounts of active ingredient with a low volume of formulation used. | 2015-04-02 |
20150093427 | Insecticidal Polymer Matrix Comprising PBO and DM - An insecticidal polymer matrix containing Piperonyl Butoxide (PBO) and deltamethrin (DM), wherein the ratio between the content of PBO and the content of DM in terms of weight is higher than 3. | 2015-04-02 |
20150093428 | 3D IN VITRO BI-PHASIC CARTILAGE-BONE CONSTRUCT - A 3D in vitro bi-phasic cartilage-bone organoid includes a layer of an artificial cartilage tissue, and a layer of an artificial bone tissue comprising a structure-giving scaffold and a bone marrow structure. The layer of the artificial cartilage tissue contacts at least one surface of the layer of the artificial bone tissue. | 2015-04-02 |
20150093429 | DEMINERALIZED BONE FIBERS HAVING CONTROLLED GEOMETRY AND SHAPES AND METHODS THEREOF - A bone repair composition and methods thereof include elongated bone fibers made from cortical bone in which a plurality of approximately uniform bone fibers is made into various implant shapes conducive for various applications. The bone fiber compositions may be in the form of a cavity, ball, pellet, wrap, strip, cylinder, cone, putty, gel, or injectable slurry. | 2015-04-02 |
20150093430 | DIAMINE OXIDASE FOR USE IN THE TREATMENT OR PREVENTION OF ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD) - The present invention refers to diamine oxidase for use in the treatment or prevention of attention deficit hyperactivity disorder (ADHD). | 2015-04-02 |
20150093431 | COMPOSITIONS - The present invention relates to a composition comprising at least one mimotope of an epitope of alpha-synuclein for use in a method for preventing and/or treating synucleinopathies, wherein said at least one mimotope is coupled or fused to a pharmaceutically acceptable carrier protein selected from the group consisting of a non-toxic diphtheria toxin mutant, keyhole limpet hemocyanin (KLH), diphtheria toxin (DT), tetanus toxid (TT) and | 2015-04-02 |
20150093432 | COMPOSITION - The present invention relates to a composition comprising at least one mimotope of an epitope of alpha-synuclein for use in a method for preventing and/or treating β-amyloidoses including Alzheimer's disease, wherein said at least one mimotope is coupled or fused to a pharmaceutically acceptable carrier protein selected from the group consisting of a non-toxic diphtheria toxin mutant, keyhole limpet hemocyanin (KLH), diphtheria toxin (DT), tetanus toxid (TT) and | 2015-04-02 |
20150093433 | TARGETED AND MODULAR EXOSOME LOADING SYSTEM - Disclosed are exosomes that include a packaging protein and a cargo RNA in which the packaging protein binds specifically to the cargo RNA. The packaging protein is a fusion protein that includes an RNA-binding domain and an exosome-targeting domain. The cargo RNA includes an RNA-motif that the RNA-binding domain of the fusion protein binds specifically such that the cargo RNA is packaged in the lumen of the exosomes. | 2015-04-02 |
20150093434 | LIPOSOMAL COMPOSITIONS OF GLUCOCORTICOID AND GLUCOCORTICOID DERIVATIVES - Provided are pharmaceutical compositions including a glucocorticoid or glucocorticoid derivative stably encapsulated in a liposome. The glucocorticoid or glucocorticoid derivative is selected from an amphipathic weak base glucocorticoid or glucocorticoid derivative having a pKa equal or below 11 and a logD at pH 7 in the range between −2.5 and 1.5; or an amphipathic weak acid GC or GC derivative having a pKa above 3.5 and a logD at pH 7 in the range between −2.5 and 1.5. The therapeutic effect of the pharmaceutical composition of the invention was exhibited in vivo with appropriate models of multiple sclerosis and cancer. | 2015-04-02 |
20150093435 | TREATMENT OF LENGTH DEPENDENT NEUROPATHY - Compositions, and methods of use thereof, are provided for the treatment of painful neuropathy by local or topical delivery of compounds that interact with α-adrenergic receptors, especially an alpha | 2015-04-02 |
20150093436 | MODIFIED RELEASE DOSAGE FORMS OF SKELETAL MUSCLE RELAXANTS - A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration—time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period. | 2015-04-02 |
20150093437 | NOVEL PHARMACEUTICAL COMPOSITION OF LINEZOLID - The present invention relates to a novel pharmaceutical composition of Linezolid. The present invention relates to a novel pharmaceutical composition comprising Linezolid Form III along with pharmaceutically acceptable excipients and a process to prepare the said composition. The present invention relates to an oral dosage forms for the treatment of severe infections caused by Gram-positive bacteria. | 2015-04-02 |
20150093438 | Tramadol for Treating Depression - There is described a sub-analgesic amount of tramadol, or a salt thereof, in the treatment, alleviation or prevention of depression in a patient wherein the sub-analgesic amount is from about 60 to 80 mg, of tramadol or a salt thereof. | 2015-04-02 |
20150093439 | COMPRESSION COATED PULSATILE RELEASE COMPOSITIONS - The present invention is directed to a dosage form comprising an immediate release portion of a first active pharmaceutical ingredient and a delayed release portion of a second active pharmaceutical ingredient wherein (a) the immediate release portion comprises from about 1 mg to about 1000 mg of the first active pharmaceutical ingredient; and (b) the delayed release portion comprises from about 1 mg to about 1000 mg of the second active pharmaceutical ingredient; wherein the delayed release portion is coated with a delayed release coating comprising at least one swellable erodible polymer and a filler, and wherein the immediate release portion is in contact with the delayed release coating. | 2015-04-02 |
20150093440 | AGGREGATE NANOPARTICULATE MEDICAMENT FORMULATIONS, MANUFACTURE AND USE THEREOF - A method of making aggregate particles suitable for a powder aerosol composition that includes forming a dispersion of nanoparticulate drug and/or excipient in a non-aqueous liquid, and spray-drying the dispersion to generate aggregate particles having a mass median aerodynamic diameter of less than or equal to about 100 microns, and particles generated by such method, and compositions of said particles. | 2015-04-02 |
20150093441 | ORAL SOLID PREPARATION COMPRISING ARIPIPRAZOLE AND METHOD FOR PRODUCING ORAL SOLID PREPARATION COMPRISING ARIPIPRAZOLE - An object of the present invention is to provide an oral solid preparation that can be produced in a simpler manner than conventional methods, that exhibits high bioavailability and high dissolubility even in persons having low stomach acid, and that can also ensure dissolubility after being allowed to stand for a certain period of time. Another object is to provide a simple method for producing the oral solid preparation. | 2015-04-02 |
20150093442 | INJECTABLE PREPARATION - An object of the present invention is to provide a storage-stable injectable preparation comprising a composition comprising a poorly soluble drug as an active ingredient and a dispersion medium. Another object of the present invention is to provide a compact, lightweight prefilled syringe by filling a syringe with the injectable preparation. The present invention provides an injectable preparation comprising a composition comprising a poorly soluble drug, a dispersion medium, and a specific suspending agent, the composition having a viscosity of 40 pascal-seconds or more in at least one point in the shear rate range of 0.01 to 0.02 s | 2015-04-02 |
20150093443 | MICROCOMPOSITES FOR TREATMENT OF BONE - Compositions having a drug-loaded microparticle and bone cement and methods of making such compositions are disclosed. Also disclosed are methods of employing such compositions for the treatment of injected joint spaces and bone disease. | 2015-04-02 |
20150093444 | BLOCK COPOLYMER, LIQUID COMPOSITE THEREOF, NUCLEIC ACID PREPARATION, PREPARATION METHODS THEREFOR, AND USE THEREOF - Provided are a polycaprolactone-polyphosphate block copolymer, a liquid composite formed by the block copolymer, a nucleic acid preparation, preparation methods for the copolymer and the liquid composite, and the use of the copolymer and the liquid composite in a nucleic acid medicine delivery system. The block copolymer prepared using the present invention has good biocompatibility, low cytotoxicity, and good biodegradability. The micelles provided in the present invention self-assemble into nano-particles in an aqueous solution, and have good stability, biocompatibility, and biodegradability, and low cytotoxicity. The preparation method is simple, has high repeatability, as a vector can protect small nucleic acids such as siRNA from biodegradation, can combine with the scale effect of nano-particles, and can be used for treating different diseases. Additionally, bonding targeting groups enable specificity recognition of different cancer cells. | 2015-04-02 |
20150093445 | FORMULATIONS AND METHODS FOR TREATMENT OF ACNE AND INFLAMMATORY SKIN CONDITIONS - Topically administrable compositions and methods for treating skin conditions in mammals, such as acne, rosacea, keratosis pilaris, photo-aging, and photo-rejuvenation. The composition includes a therapeutic amount of antihistamine selected from the group consisting of a non-sedating antihistamine, a physiologically acceptable acid of a non-sedating antihistamine, a salt of a non-sedating antihistamine, an amide of a non-sedating antihistamine, and a combination of two or more of these, and emu oil product selected from the group consisting of emu oil, a biologically active fraction of emu oil, and a combination of these. The composition further includes a therapeutic amount of topical retinoid. The combination of non-sedating antihistamine and retinoid with emu oil has been found to produce a synergistic effect that is more effective in the treatment of skin conditions than the compound used separately. | 2015-04-02 |
20150093446 | Exfoliating Body Scrub Composition - An exfoliating body scrub composition is made from natural ingredients. The body scrub composition comprises ground coffee; ground whole oats; dry milk; from about 0.5% by weight to about 5% by weight of soy flour, based on the total weight of the coffee; oats; dry milk; and soy flour. The body scrub composition further comprises an optional carrier, such as an aqueous carrier, a moisturizing nonaqueous carrier, or a solid carrier. The body scrub composition may be made by combining solid ingredients comprising ground coffee, ground whole oats, dry milk, and from about 0.5% by weight to about 5% by weight of soy flour; and mixing the solid ingredients to produce a uniform powdered mixture. The uniform powdered mixture is optionally mixed with a carrier. | 2015-04-02 |
20150093447 | STEM CELL IDENTIFICATION AND PURIFICATION METHOD - The invention provides a composition comprising enriched extracellular vesicles, wherein the extracellular vesicles express VSEL markers. The extracellular vesicles are used to treat or regenerate damages or injured tissue in a subject. | 2015-04-02 |
20150093448 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Angiopoietin-related protein 3, Soluble Lymphatic vessel endothelial hyaluronic acid receptor 1, and Vascular endothelial growth factor D as diagnostic and prognostic biomarkers in renal injuries. | 2015-04-02 |
20150093449 | Method of Using Silicon Substituted Phosphates to Improve Healing of Bone and Soft Tissue - A method of use of silicon substituted phosphates that improves bone and soft tissue growth resulting in better adhesion and fixation of implanted prosthetics, which may be used as part of a tissue engineering scaffold for ligament replacement and results in improved healing of healing of damaged bone and soft tissue ulcers. The silicon substituted phosphates of various chemical composition and granular sizes may be used in direct application or in combination with other materials, not previously claimed in prior art used to treat the various medical conditions described. | 2015-04-02 |
20150093450 | METHODS AND COMPOSITIONS FOR REDUCING OR PREVENTING VASCULAR CALCIFICATION DURING PERITONEAL DIALYSIS THERAPY - Methods and compositions for reducing, preventing or reducing the progression of calcification in peritoneal dialysis patients are provided. In an embodiment, the present disclosure provides a method comprising administering to a patient during peritoneal dialysis therapy a dialysis solution comprising a therapeutically effective amount of pyrophosphate ranging between about 30 μM and about 400 μM. Formulations of dialysis solutions according to the dose ranges claimed in the present disclosure allow therapeutic amounts of pyrophosphate to be delivered to peritoneal dialysis patients. | 2015-04-02 |
20150093451 | METHOD OF INCREASING ENERGY EXPENDITURE - Methods are disclosed of the increasing resting metabolic rate of a subject comprising administering a composition comprising a mixture of reduced species and reactive oxygen species, wherein the mixture of reduced species and reactive oxygen species increases the resting metabolic rate of the subject. The reactive oxygen species can comprises at least one superoxide The process of making the composition comprises the steps of purifying water to produce ultra-pure water, combining sodium chloride to the ultra-pure water to create salinated water, and electrolyzing the salinated water at a temperature of about 4.5° C. to about 5.8° C. The electrolyzing is accomplished with an anode, a cathode and a power source. The power source comprises a transformer and a rectifier and does not comprise a filter capacitor. The method can also include contacting at least one cell of the subject with the composition. | 2015-04-02 |
20150093452 | COMPOSITIONS AND METHODS FOR DISINFECTING AND CLEANING CONTACT LENSES - This invention relates generally to disinfection and cleaning systems for medical devices. In a preferred embodiment, the invention relates to compositions, methods and articles for simultaneously cleaning and disinfecting contact lenses. The present invention is directed to ophthalmic compositions containing one or more block copolymers referred to as (polyoxyethylene)-(poly-oxybutylene) block copolymers (“PEO-PBO”). The invention is particularly directed to the use of PEO-PBO di-block copolymers as non-foaming wetting agents in peroxide-based compositions for disinfecting contact lenses. | 2015-04-02 |
20150093453 | Continuous Methods for Treating Liquids and Manufacturing Certain Constituents (e.g., Nanoparticles) in Liquids, Apparatuses and Nanoparticles and Nanoparticle/Liquid Solution(s) Resulting Therefrom - This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred. The continuous process causes at least one liquid to flow into, through and out of at least one trough member, such liquid being processed, conditioned and/or effected in said trough member(s). Results include constituents formed in the liquid including micron-sized particles and/or nanoparticles (e.g., metallic-based nanoparticles) of novel size, shape, composition and properties present in a liquid. | 2015-04-02 |
20150093454 | COMPOSITION COMPRISING ALPHA-LIPOIC ACID AND HONOKIOL FOR TREATING NEUROPATHIES - The present invention relates to a composition comprising alfa-lipoic acid, or a salt or complex thereof, and honokiol, wherein the weight quantity of said honokiol is between 1% and 30% with respect to the total weight of honokiol and alfa-lipoic acid. | 2015-04-02 |
20150093455 | COMPOSITIONS AND METHODS FOR INCREASING TELOMERASE ACTIVITY - The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical, including topical, and nutraceutical formulations. The methods and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient, such as, for example, HIV infection, various degenerative diseases, and acute or chronic skin ailments. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and proliferation of stem cells. | 2015-04-02 |
20150093456 | PHARMACEUTICAL COMPOSITION FOR TREATING WOUNDS OR REVITALIZING SKIN COMPRISING EUPHORBIA KANSUI EXTRACTS, FRACTIONS THEREOF OR DITERPENE COMPOUNDS SEPARATED FROM THE FRACTIONS AS ACTIVE INGREDIENT - The present invention relates to a pharmaceutical composition for treating wounds or revitalizing skin comprising the | 2015-04-02 |
20150093457 | Topical Compositions Comprising Fermented Extracts of Traditional Chinese Medicinal (TCM) Ingredients, and Methods of Making and Using Same - The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products. | 2015-04-02 |
20150093458 | NUTRACEUTICAL COMPOSITION FOR PDE4 INHIBITION, ENHANCED DOPAMINE METABOLISM AND LONG TERM POTENTIATION - A nutritional supplement for increasing cognitive functioning. The supplement includes a flavonoid such as luteolin and a labdane diterpene such as forskolin. The supplement can also include one or any combination of L-phenylalanine, L-carnitine, acetyl-L-carnitine, and vitamin B6. Artichoke extract can be used as a source of luteolin. Methods of using the nutritional supplements to increase cognitive functioning are also included. | 2015-04-02 |
20150093459 | BIOACTIVE COMPLEX COMPOSITIONS AND METHODS OF USE THEREOF - A bioactive complex composition having enhanced oxidative stability, emulsion stability, mineral rich transparent beverages and a wide range of functional health benefits. The composition may include as a base composition individual ingredients or a synergistic blend of mineral salts, Omega-3 rich oils, phospholipids, chitosan, and alpha-casein, beta-casein, kappa-casein or protein fragments, glycopeptides, phosphopeptides. The composition may optionally be further utilized for the prevention of hypercholesterolemia, bone (and teeth) mineral loss, treatment of mental health diseases, heart health, additional nutritional supplementation, and treatment of additional medical conditions. | 2015-04-02 |
20150093460 | ANTI-OXIDANT PROPERTIES OF CORNUS SERICEA - It has been discovered that Red Osier Dogwood can be fed to domesticated animals such as livestock as part of a feeding regimen in place of silage. Surprisingly, the Red Osier Dogwood results in increased growth compared to a control fed a regular diet. Experiments have shown that the Red Osier Dogwood is rich in antioxidants such as rutin, gallic acid, ellagic acid, quercetin and tyrosol. Also described herein are methods of preparing extracts from Red Osier Dogwood comprising high levels of these antioxidants, which can be used in the preparation of medicaments for the administration to animals, including humans. | 2015-04-02 |
20150093461 | Topical Compositions Comprising Fermented Extracts of Traditional Chinese Medicinal (TCM) Ingredients, and Methods of Making and Using Same - The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products. | 2015-04-02 |
20150093462 | Watery Lotion Skin Care Compositions And Methods - A watery lotion composition for topical application to skin comprising at least one extract from the fermentation of the microorganism | 2015-04-02 |
20150093463 | NUTRITIONAL COMPOSITION CONTAINING A PEPTIDE COMPONENT WITH ANTI-INFLAMMATORY PROPERTIES AND USES THEREOF - The present disclosure relates to nutritional compositions comprising a protein equivalent source, wherein 20% to 80% of the protein equivalent source includes a peptide component comprising SEQ ID NO 4, SEQ ID NO 13, SEQ ID NO 17, SEQ ID NO 21, SEQ ID NO 24, SEQ ID NO 30, SEQ ID NO 31, SEQ ID NO 32, SEQ ID NO 51, SEQ ID NO 57, SEQ ID NO 60, and SEQ ID NO 63, and 20% to 80% of the protein equivalent source comprises an intact protein, a partially hydrolyzed protein, or combinations thereof. The disclosure further relates to methods of reducing the inflammatory response and/or production of proinflammatory cytokines, i.e. Interleukin-17, by providing said nutritional compositions to a target subject. | 2015-04-02 |
20150093464 | ROTARY ATOMIZER HAVING ELECTRO-MAGNETIC BEARINGS AND A PERMANENT MAGNET ROTOR - An improved rotary disc atomizer for use in, for example, spray dryers or congealers is disclosed. The rotary disc may be directly mounted to the shaft of a high-speed electrical motor. The high-speed electrical motor comprises a permanent magnet rotor and electro-magnetic bearings. The electro-magnetic bearings may be supported by one or more upper/lower bearing housings and used to enable frictionless support of the shaft/rotor and rotary disc. The atomizer system may further comprise a gas distributor enabled to dynamically adjust the velocity at which the gas leaves the radial vanes and meets with the atomized droplets. | 2015-04-02 |
20150093465 | Material Dispensing System - Additive manufacturing systems and apparatus include, in one aspect, a material deposition system including an extruder for deposition materials, the extruder including two or more material entry ports, a mixing chamber, and an exit orifice; and a controller coupled with the extruder to dynamically change delivery rates of the deposition materials to be mixed in the mixing chamber before flowing from the exit orifice; wherein the controller combines a desired volume flow rate of material to flow from the exit orifice with a mix ratio to specify the delivery rates of the deposition materials. The system can include filament drive systems to feed the thermoplastic materials in filament form into the entry ports, and the controller can dynamically change the mix ratio when operating the filament drive systems to control one or more properties of the material to flow from the exit orifice. | 2015-04-02 |
20150093466 | APPARATUS FOR IMPROVING RADIO FREQUENCY SIGNAL TRANSMISSION THROUGH LOW-EMISSIVITY COATED GLASS - A method and apparatus for modifying low emissivity (low-E) coated glass, so that windows using the processed glass allow uninterrupted use of RF devices within commercial or residential buildings. Glass processed in the manner described herein will not significantly diminish the energy conserving properties of the low-E coated glass. This method and apparatus disrupts the conductivity of the coating in small regions. In an embodiment, the method and apparatus ablates the low-E coating along narrow contiguous paths, such that electrical conductivity can no longer occur across the paths. The paths may take the form of intersecting curves and/or lines, so that the remaining coating consists of electrically isolated areas. The method and apparatus are applicable both to treating glass panels at the factory as well as treating windows in-situ after installation. | 2015-04-02 |
20150093467 | FEED ROLL FOR STRAND PELLETIZERS AND METHOD FOR PRODUCING SUCH A ROLL - A feed roll for a strand pelletizer and a method for producing the feed roll for a strand pelletizer. The feed roll comprises a metallic roll core and a sheathing located on the metallic roll core. The sheathing can comprise a plastic material and at least one metal mesh. The feed roll can be produced by: providing a metallic roll core, arranging a metallic mesh on the roll core, and molding over the metallic mesh with a plastic material to form the sheathing. | 2015-04-02 |
20150093468 | Apparatus And System For Expanding Expandable Polymeric Microspheres - An apparatus including: (a) a steam generator having a power output of less than or equal to about 6 boiler horsepower; (b) a steam conduit in fluid communication with the steam generator; (c) a fluid material conduit in fluid communication with a source of a fluid material, wherein the fluid material includes unexpanded, expandable polymeric microspheres; (d) a treatment zone in fluid communication with the steam generator via the steam conduit, and with the fluid material conduit, such that the fluid material is contacted by steam within the treatment zone; and (e) a back pressure generator in fluid communication with the treatment zone, capable of increasing pressure in the treatment zone, which results in expansion of the expandable polymeric microspheres when the fluid material exits the treatment zone. | 2015-04-02 |
20150093469 | ORGANOMETALLIC COMPLEX, POWDER INTENDED FOR ANIMAL FEED AND PREPARATION METHODS THEREOF - The invention relates to an organometallic complex of the amino acid/metal type. The complex is a crystalline pluri-metal complex that can be obtained in the form of a homogeneous powder that can be used to optimise animal feed. More specifically, the invention relates to an organometallic complex that is characterised in that it is formed by at least one amino acid or amino acid derivative with at least two different metals. The invention also relates to a powder comprising the organometallic complex of the invention, as well as to methods for preparing such a powder. | 2015-04-02 |
20150093470 | REDUCED CALORIE BEVERAGE OR FOOD PRODUCT AND PROCESS AND APPARATUS FOR MAKING SAME - The invention relates to a process for preparing a reduced calorie beverage or food product employing fermentation of a plant-derived juice or liquid and removing the ethanol therefrom. The process involves first converting at least some of the sugar in a plant-derived juice or liquid by fermenting it with yeast to produce a fermentation product containing ethanol and subsequently removing at least some of the ethanol from the fermentation product, while maintaining the fermentation product at a temperature of less than fifty-five degrees Celsius to produce the reduced calorie beverage or food product. The alcohol removal step is performed at temperatures of less than seventy-five degrees in order to reduce the impact upon flavour and nutritional properties, relative to conventional alcohol removal at or near boiling temperatures. This invention also relates to an apparatus for performing the process for preparing a reduced calorie beverage or food product and to the reduced calorie juices and juice products created using this process and apparatus. | 2015-04-02 |
20150093471 | BREWING METHOD - A fermenter is provided that heats and ferments a beverage feed material, such as grain and water, and a mashing device having a porous and permeable bottom to be positioned in the fermenter during heating to form an intermediate beverage feed material, such as a wort. | 2015-04-02 |
20150093472 | ASPARAGINASE FROM BASIDIOMYCETES - An asparaginase enzyme derived from the fungi Basidiomycete, in particular the Basidiomycete is | 2015-04-02 |
20150093473 | CULTURES WITH IMPROVED PHAGE RESISTANCE - The present invention provides methods and compositions related to modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some preferred embodiments, the present invention provides compositions and methods for the use of one or more cas genes or proteins for modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some embodiments, the present invention provides methods and compositions that find use in the development and use of strain combinations and starter culture rotations. In additional embodiments, the present invention provides methods for labelling and/or identifying bacteria. In some preferred embodiments, the present invention provides methods for the use of CRISPR loci to determine the potential virulence of a phage against a cell and the use of CRISPR-cas to modulate the genetic sequence of a phage for increased virulence level. In still further embodiments, the present invention provides means and compositions for the development and use of phages as biocontrol agents. | 2015-04-02 |
20150093474 | PROTEIN-RICH FEEDSTUFF WITH RESISTANCE TO LOWERED DIGESTIBILITY DUE TO HEAT DAMAGE - Protein-rich feedstuffs which contain at least one protein feed material and either betaine or at least one feed product which contains betaine are resistant to reduction of digestibility as a result of heat damage during drying. | 2015-04-02 |
20150093475 | Method for Facilitating Selection of a Pet Food - A method for facilitating the selection of a pet food based on the nutrient sources. A first pet food product and a second pet food product can be provided. Each pet food product can be put in a package and each package can have a primary nutrient source region with protein source indicia and a secondary nutrient region with secondary nutrient source indicium. The protein source indicia on the first and second package can be different. The primary source region and the secondary source region can comprise great than about 50% of the area of the front side of the package. | 2015-04-02 |
20150093476 | SUGAR-REDUCED FROSTED CEREAL PRODUCT - A frosted cereal product includes a cereal base and a frosting on the cereal base. The frosting is a composition containing a sugar, in an amount of at most 90% by weight (dry matter of the frosting), and a raw starch, in an amount of at least 10% by weight (dry matter of the frosting); the weight ratio between the cereal base and the frosting lies between 1:0.05 and 1:2; and the frosting consists of 1 to 5 layers. | 2015-04-02 |
20150093477 | Multi-Function Dual-Opening Retail Beverage Container - A hermetically sealed dual-opening beverage container that functions as a mixing instrument, drinking straw, and a shot delivery (or shooter) device suitable for retail distribution is disclosed. An example embodiment includes a hermetically sealed beverage container for retail distribution including a vessel having a generally right rectangular prism shape, a first cap and a second cap both having a generally cube shape. Example embodiments of the hermetically sealed dual-opening beverage container reduce the amount of wasted space in the packaging and distribution process because of its efficient shape. Further, example embodiments of the container can poured contents at a faster rate, and can be reused and recycled. Further, the disclosed subject matter can be utilized as a straw and mixing device, like a stirrer, and makes consuming a shot from a bottle easier and quicker. This results in increased efficiency, increased functionality and increased pouring speed. | 2015-04-02 |
20150093478 | ABSORBENT PAD TO REDUCE CONFINEMENT ODOR IN FOOD PACKAGES - An absorbent pad that contains activated carbon to reduce confinement odor in a vacuum-packaged food product is provided. An embodiment of absorbent pad contains activated carbon and an antimicrobial agent that further reduces confinement odor by two mechanisms of action: reducing bacterial counts in the liquid purge that cause breakdown of carbohydrates and proteins in food products; and trapping of confinement odor-causing breakdown products by the activated carbon. The absorbent body in the absorbent pad actively draws in liquid purge and dissolved volatile breakdown products in the vacuum package that produce confinement odor, which produces greater and more rapid contact of odor-causing compounds with the activated carbon. | 2015-04-02 |
20150093479 | Birch Sap Beverage - A birch sap beverage having an extended shelf life and process for the manufacture thereof in which a birch sap is adjusted to a standard pre-determined Brix value and then subjected to either (a) ultra-high temperature (UHT) pasteurization followed with aseptic packaging (b) packaging followed by UHT. Additional birch sap products having extended shelf life are also disclosed and claimed. | 2015-04-02 |
20150093480 | Barbecue Seasoning Utensil - A barbecue utensil having a hollow cylindrical handle with a plunger access opening along the back side of the handle; food handling means removably attachable by an adapter to the bottom end of the handle; and a fluid syringe having a plunger at a top end and a fluid outlet at a bottom end, the syringe reversibly insertable into the bottom end of the handle, wherein the fluid outlet is reversibly connectable to the top end of the food handling means, which may be a fork, basting brush or spatula, for discharge of a fluid seasoning from a syringe into or onto a food item. A food thermometer or grill cleaning brush may also be attached to the handle. | 2015-04-02 |
20150093481 | METHOD AND SYSTEM FOR RECAPTURING AND REUSING UNREACTED ANTIMICROBIAL SOLUTIONS IN SPRAY APPLICATIONS - A system providing for on-site reclamation and re-use of reclaimed antimicrobial solution includes a dispenser, at least one receptacle, piping, and at least one pump. The dispenser sprays antimicrobial solution toward moving raw food products. Unspent antimicrobial solution that did not contact the moving raw food products and rebound antimicrobial solution that did contact the raw food products combine to form a reclaimed antimicrobial solution. The reclaimed antimicrobial solution is collected in the receptacle and is pumped through the piping to a location for reuse. | 2015-04-02 |
20150093482 | AQUEOUS CHLOROUS ACID SOLUTION FOR USE AS DISINFECTANT - A process for producing aqueous chlorous acid solution in which chlorous acid, which is safe for the human body, is easy to handle, and less generates chlorine dioxide, is yielded and used as a disinfectant for a pretreatment in food processing. To an aqueous sodium chlorate solution is added sulfuric acid or an aqueous solution thereof in such an amount and concentration that the pH of the aqueous solution can be kept at 2.3-3.4 to thereby react them and generate chloric acid. Subsequently, hydrogen peroxide is added to the chloric acid in an amount which is equal to or larger than the amount necessary for a reduction reaction to thereby yield chlorous acid. Any one of inorganic acids, inorganic acid salts, organic acids, and organic acid salts, or two or more thereof, or a combination or these is added to the aqueous solution containing chlorous acid yielded, whereby the chlorous and acid can be present for long and the pH of the aqueous solution is regulated to regulated to 3.2-7.0. Thus, high bactericidal power is imparted thereto. | 2015-04-02 |
20150093483 | APPARATUS FOR BREWING A BEVERAGE AND RELATED METHOD - Disclosed is an apparatus for brewing a beverage, such as coffee, as well as associated methods for brewing a beverage. Apparatuses and methods are disclosed to reduce labor involved in pour-over brewing techniques, while providing greater consistency in the results. Manual and/or automatic movements are provided to a filter (e.g., rotation) and/or a nozzle dispensing liquid over the filter. Water dosage and timing therefore can be automated to the filter. The nozzle can be positioned off-center with respect to the filter to ensure wetting thereof. The nozzle can be made movable for constrained changes to the path of liquid flow relative to the rotating filter. | 2015-04-02 |
20150093484 | MULTI-LAYER MEMBRANE CAPSULE FOR PREPARING A BEVERAGE - A system, method and capsule are usable for preparing a predetermined quantity of beverage suitable for consumption using an extractable product. The system includes an exchangeable capsule, and an apparatus including a receptacle for holding the exchangeable capsule, and a fluid dispensing device for supplying a fluid to the exchangeable capsule. The exchangeable capsule includes a circumferential wall, a bottom, and a lid. The wall, bottom and lid enclose an inner space including the extractable product. The receptacle includes bottom piercing means intended for piercing an entrance area of an alternative capsule for creating at least one entrance opening for supplying the fluid to the extractable product. The entrance area of the capsule includes an entrance filter for supplying the fluid to the extractable product there through. In use, the entrance filter is positioned at a distance from the bottom piercing means, such that the capsule of the system is not pierced by the bottom piercing means. The filter is a multi-layer filter including at least a first layer and a second layer bonded together. The first layer has a higher tear strength than the second layer and the second layer has a higher stiffness than the first layer. | 2015-04-02 |
20150093485 | METHOD FOR THE SELECTIVE REMOVAL OF SULFITES FROM BEVERAGES AND MODULAR APPARATUS FOR SAME - The disclosure provides a method for selectively removing sulfites, for example bisulfite anionic species, from a beverage comprising free sulfite by providing an effective amount of a non-ionic, solid phase material and contacting the beverage with the solid phase material thereby sequestering the free sulfite on the non-ionic, solid phase material and providing a beverage having a reduced amount of free sulfite that otherwise maintains the general chemical composition with which it started. The disclosure further provides a device for selectively removing sulfite from a beverage comprising a container for receiving a beverage comprising free sulfite, said container enclosing a non-ionic, solid phase material capable of sequestering free sulfite, and a modular apparatus comprising a sulfite capture module and optionally a sediment filter module or an aeration module. Optionally, the non-ionic solid phase material is food-safe. | 2015-04-02 |
20150093486 | Nozzle Device And Nozzle For Atomisation And/Or Filtration And Methods For Using The Same - Nozzle device and nozzle for atomisation and/or filtration as well as methods for using the same. The present invention relates to a nozzle and nozzle device for atomisation, in particular a micro-machined reinforced nozzle plate, that may produce small liquid droplets in air (spray) or into a liquid (emulsion) with a narrow droplet size distribution and to make small air bubbles into a liquid (foam) and to methods of making the same. The invention is further related to a nozzle part for filtration as well as means and methods to facilitate atomisation and filtration. | 2015-04-02 |
20150093487 | HEATING PAD ASSEMBLY FOR CONTAINER WARMING - Disclosed herein are heating pad assemblies for a food serving container, wherein the assemblies comprise a heating pad and a pouch configured to hold the heating pad. Also disclosed are methods for warming a food serving container comprising steps of obtaining a heating pad; heating the heating pad; placing the warm heating pad in a pouch to obtain a heating pad assembly; and placing the heating pad assembly under the container. | 2015-04-02 |
20150093488 | DEVICE FOR FORMING PORTIONS OF FOOD IN MULTIPLE RECEPTACLES - A device for forming portions of food is proposed, comprising a hydraulic press. rne press has at least one hydraulic pressure generator and at least two actuators, wherein each of the actuators comprises a working cylinder and the working cylinders are hydraulically connected. It is preferably provided that a die has at least two separate receptacles for receiving portions of food. The receptacles interact with respective pressing tools, and the pressing tools can in each case be moved by means of an actuator, in particular by means of a pressing ram. | 2015-04-02 |
20150093489 | FOOD COMPOSITION COMPRISING A BLEND OF CELLULOSE ETHERS - The presently disclosed and claimed inventive concept(s) relates generally to a food composition for reducing fat comprising flour and a binder, and methods of making the composition and using the composition to reduce fat in fried and baked foods. The binder is a blend of two or more different water soluble cellulose ethers. | 2015-04-02 |
20150093490 | PROCESS FOR THE HUMANIZATION OF ANIMAL SKIM MILK AND PRODUCTS OBTAINED THEREBY - The invention relates to a process for the treatment of animal skim milk and for the production of an infant formula base product from animal skim milk, which process is highly efficient and cost effective, as only membrane filtration techniques, such as microfiltration and ultrafiltration, are required. By carefully controlling the process parameters, a product is obtained in which most of the major components are within the desired range for an infant formula base product. The invention also relates to products obtainable by the process according to the invention. | 2015-04-02 |
20150093491 | Method and Apparatus For Aging Coffee - A method and apparatus for aging coffee, which both accelerates the aging process, and also imparts and develops a desired flavor profile in the finished (roasted and brewed) bean. Beneficial results are obtained by placing unroasted coffee in intimate contact with or in proximity to aging compounds of interest. | 2015-04-02 |
20150093492 | OIL AND FAT COMPOSITION SUITABLE FOR NON-TEMPERING HARD BUTTER - [Object] To provide an oil and fat composition suitable for non-tempering type hard butter that is a low trans fatty acid and non-lauric type and an oil-based food product comprising such an oil and fat composition, the productivity of which is good. | 2015-04-02 |
20150093493 | METHOD FOR PROVIDING A COCOA REPLACER BASED ON A MATERIAL SELECTED FROM ROASTED WHEAT, ROASTED AND/OR MALTED BARLEY - A method of providing a cocoa replacer based on a material selected from roasted wheat, roasted and/or malted barley, comprising the steps of
| 2015-04-02 |
20150093494 | Bioactive Additive - The bioactive additive is made by processing bee pollen. The bioactive additive includes 33% to 40% by weight of bee pollen, 20% to 33% by volume of water, and 33% to 40% by volume of an alcohol such as ethanol. The bioactive additive, when added to products such as bread and bread-like products, enriches the products with amino acids, vitamins, and minerals. The bioactive additive can be used in food production, for example, in the preparation of bread and bread-like products. | 2015-04-02 |
20150093495 | Nucleic Acids, Cells, and Methods for Producing Secreted Proteins - A method for producing a secreted recombinant polypeptide sequence is provided. In some embodiments it comprises providing a recombinant microorganism comprising a recombinant nucleic acid comprising a first nucleic acid sequence encoding the recombinant polypeptide sequence operatively linked to a second nucleic acid sequence encoding a signal peptide; and culturing the recombinant microorganism in a culture medium under conditions sufficient for production and secretion of the recombinant protein by the recombinant microorganism. In some embodiments the coding sequence for the signal peptide is not native to the recombinant microorganism. In some embodiments the recombinant microorganism is photo synthetic. Also provided are recombinant photosynthetic microorganisms, isolated polypeptides comprising a signal peptide comprising an amino acid sequence disclosed herein, and isolated nucleic acids comprising a coding sequence for one of the signal peptides, among other things. | 2015-04-02 |
20150093496 | MEDICAL DEVICE COATINGS FOR RELEASING A THERAPEUTIC AGENT AT MULTIPLE RATES - Medical device coatings are provided that simultaneously release a therapeutic agent at different rates from different portions of the medical device coating. In a first embodiment, medical device coatings are provided that include particles comprising a therapeutic agent with two or more different particles sizes within a single layer on a surface of the implantable device. In a second embodiment, medical device coatings are provided having a higher concentration of the therapeutic agent in a first region of the coating than in a second region of the coating. In a third embodiment, medical device coatings are provided that are formed by certain coating processes wherein the droplet size of a spray coating solution is changed during the coating process. These coating processes preferably include applying a solution comprising a therapeutic agent and a suitable solvent to a surface of an implantable medical device. In a fourth embodiment, methods of treatment are provided that include implanting a coated medical device. | 2015-04-02 |
20150093497 | MULTI-LEVEL THIN FILM CAPACITOR ON A CERAMIC SUBSTRATE AND METHOD OF MANUFACTURING THE SAME - In accordance with the teachings described herein, a multi-level thin film capacitor on a ceramic substrate and method of manufacturing the same are provided. The multi-level thin film capacitor (MLC) may include at least one high permittivity dielectric layer between at least two electrode layers, the electrode layers being formed from a conductive thin film material. A buffer layer may be included between the ceramic substrate and the thin film MLC. The buffer layer may have a smooth surface with a surface roughness (Ra) less than or equal to 0.08 micrometers (um). | 2015-04-02 |
20150093498 | METHOD AND APPARATUS FOR AUTOMATICALLY ADJUSTING DISPENSING UNITS OF A DISPENSER - A dispensing apparatus includes a frame having a gantry configured to provide movement in the X axis and Y axis directions, and first and second dispensing units coupled to the gantry and configured to dispense material onto a substrate. The second dispensing unit is coupled to the gantry by an automatic adjustment mechanism. The dispensing apparatus further includes a controller configured to control the operation of the gantry, the first dispenser, the second dispenser, and the automatic adjustment mechanism. The automatic adjustment mechanism is configured to move the second dispenser in the X axis and Y axis directions to manipulate a spacing between the first dispensing unit and the second dispensing. Methods of dispensing material on the substrate are further disclosed. | 2015-04-02 |
20150093499 | INSULATING MATERIAL FOR ROTATING MACHINES - An insulating material and its method of use of insulating material for rotating machines such as motors and generators. The insulating material includes a resin embedded with a filler that is not based only on a monomodal nanoparticle size particle distribution. Radiation erodes the material and is conductive to the formation of in situ protective layers on the body to be insulated. | 2015-04-02 |
20150093500 | Corrosion-Resistant Silver Coatings with Improved Adhesion to III-V Materials - The electrical and optical performance of silver LED reflective contacts in III-V devices such as GaN LEDs is limited by silver's tendency to agglomerate during annealing processes and to corrode on contact with silver-reactive materials elsewhere in the device (for example, gallium or aluminum). Agglomeration and reaction are prevented, and crystalline morphology of the silver layer may be optimized, by forming a diffusion-resistant transparent conductive layer between the silver and the source of silver-reacting metal, (2) doping the silver or the diffusion-resistant transparent conductive layer for improved adhesion to adjacent layers, or (3) doping the silver with titanium, which in some embodiments prevents agglomeration and promotes crystallization of the silver in the preferred <111> orientation. | 2015-04-02 |
20150093501 | RARE EARTH MAGNET AND ITS PREPARATION - A rare earth magnet is prepared by disposing a R | 2015-04-02 |
20150093502 | BRIGHT COLOURED SURFACE LAYER - A method to produce a pale and/or plain coloured wear resistant surface layer by using a dry powder layer comprising a mix of refined fibres binder, pigment and wear resistant particles. | 2015-04-02 |
20150093503 | TANTALUM OXIDE COATINGS - A process for the deposition of tantalum oxide on a substrate from a precursor mix comprising a halide of tantalum and an organic oxygen source. The process lends itself in particular to on line coating during the float glass manufacturing process, where residual heat is used to effect thermal decomposition of the organic oxygen source. | 2015-04-02 |
20150093504 | Coating Reinforcement Application and Method - A method for applying a polymer to a substrate having a first surface and a second surface (such as an inside surface and outside surface). One or more apertures are provided through the substrate, with the apertures linking the first and second surfaces. A polymer coating is applied to the first and second surfaces, with some of the polymer coating flowing into and remaining within the aperture(s). The polymer coating within the aperture(s) serves to link the polymer coating covering the first surface and the polymer coating covering the second surface. The invention also encompasses coated objects made using the inventive method. | 2015-04-02 |
20150093505 | Rotolined Articles - The present invention relates to the field of steel pipes and vessels rotolined with metallocene-produced polyethylene. | 2015-04-02 |
20150093506 | METHOD FOR 3-D PRINTING A PATTERN FOR THE SURFACE OF A TURBINE SHROUD - A method of making an article of manufacture is provided and includes the steps of spraying a first coating onto a substrate, and depositing a second coating on the first coating by 3-D printing a material disposed in a pattern. The pattern includes ridges disposed at a base surface of a turbine part. Each ridge defined by first and second sidewalls, each sidewall having a first and second end. The ends extend from the base surface, the sidewalls slope toward each other until meeting at second ends of respective first and second sidewalls defining a centerline and a top portion of the ridge. The sidewalls are inclined with substantially equal but opposite slopes with respect to the base surface. The ridges correspond to a back portion of a turbine bucket and are oriented at a first angle with respect to an axis of rotation of the bucket. | 2015-04-02 |