13th week of 2014 patent applcation highlights part 47 |
Patent application number | Title | Published |
20140087409 | NEAR-INFRARED SILVER SULFIDE QUANTUM DOT, PREPARATION METHOD THEREFOR AND BIOLOGICAL APPLICATION THEREOF - Provided are near-infrared silver sulfide quantum dots, a preparation method thereof and a biological application thereof. The silver sulfide quantum dots have hydrophilic groups derived from a mercapto-containing hydrophilic reagent attached on the surface thereof, and the hydrophilic reagent is any one of mercaptoacetic acid, mercaptopropionic acid, cysteine, cysteamine, thioctic acid and ammonium mercaptoacetate or any combination thereof. The silver sulfide quantum dots have high fluorescence yield, good fluorescence stability, good biocompatibility and uniform sizes. The preparation method has moderate reaction conditions, simple operation, short production cycle, good reproducibility and is easy to control. The silver sulfide quantum dots can be used in the application of cellular imaging and biological tissue imaging. | 2014-03-27 |
20140087410 | CULTURE CONTAINER, CULTURE OBSERVATION APPARATUS AND CULTURE OBSERVATION METHOD - A culture container includes a first transparent member being capable of keeping a predetermined temperature; a second transparent member facing to the first transparent member; a housing member to which the first transparent member and the second transparent member are adhered forming a culture space being capable of housing a well plate together with the first transparent member and the second transparent member; and a sealing member for sealing a liquid injected into the culture space between the first transparent member and the housing member. | 2014-03-27 |
20140087411 | SYSTEM AND METHOD FOR DETERMINING TUMOR INVASIVENESS - A method of determining invasion potential of a tumor cell includes exposing a tumor cell to an activity sensor; after exposing the tumor cell to the activity sensor, stimulating the tumor cell to cause a response in the cell that is reported by the activity sensor; detecting the level of response after stimulation of the tumor cell; and determining the invasion potential of the tumor cell based on the response. A system for determining the invasion potential of a tumor cell includes a sample stage that supports the tumor cell; a stimulator that focuses energy on the tumor cell to stimulate the tumor cell; and an imaging apparatus that observes an effect of the beam on the tumor cell. | 2014-03-27 |
20140087412 | Method and Device for Application of Fluid Forces to Cells - A system and method of determining biomechanical properties of a cell. A cell is introduced into a multiport flow device, the device being configured such that during fluid flow at least one stagnation zone arises in an expected location within the device. The cell is trapped in the stagnation zone of the device. A selected physical stimulus is applied to the cell, such as rotation, stretching or time-varying shear rate. The cell is observed while trapped to detect an absolute, differential and/or transient effect of the applied physical stimulus and to thereby determine biomechanical properties of the cell. Disease diagnosis may follow, by comparison to a normal control. Selectively directing the cell to a chosen outlet based on observed properties provides cell sorting, which may be implemented in parallel to increase throughput and/or in series to enlarge sorting criteria. Micro-particles may be investigated by use of appropriate particle model. | 2014-03-27 |
20140087413 | AUTOMATIC ASEPTIC SAMPLING VALVE FOR SAMPLING FROM ENCLOSED CONTAINERS - A sample can be collected from an enclosed container by opening a sample collection valve and drawing the sample from the enclosed container. After delivery of the sample out of a fluid flow path, a sanitizing fluid can be directed along the fluid flow path to sanitize the fluid flow path. | 2014-03-27 |
20140087414 | MAGNETOPHORETIC ANALYTE SELECTION AND CONCENTRATION - Devices and methods for magnetophoretic analyte selection and concentration are described. Magnetically marked analytes (e.g., cells) may be separated out of a sample dynamically in flux, such that the magnetically marked analytes are present in a highly concentrated manner in a reduced sample volume. The analyte selection may be followed by an analysis. | 2014-03-27 |
20140087415 | EMBRYO QUALITY ASSESSMENT BASED ON BLASTOMERE CLEAVAGE AND MORPHOLOGY - The present invention relates to a method and to a system for selecting embryos for in vitro fertilization based on the timing, and duration of observed cell cleavages and associated cell morphology. One embodiment of the invention relates to a method for determining embryo quality comprising monitoring the embryo for a time period, and determining one or more quality criteria for said embryo, wherein said one or more quality criteria is based on the extent of irregularity of the timing of cell divisions when the embryo develops from four to eight blastomeres, and/or wherein said one or more quality criteria is based on determining the time of cleavage to a five blastomere embryo (t5) and wherein t5 is between 48.7 hours and 55.6 hours, and/or wherein said one or more quality criteria is based on the ratio of two time intervals, each of said two time intervals determined as the duration of a time period between two morphological events in the embryo development from fertilization to eight blastomeres, and based on said one or more quality criteria determining the embryo quality. | 2014-03-27 |
20140087416 | METHODS AND COMPOSITIONS FOR PRODUCING INDUCED HEPATOCYTES - The present invention relates to methods and compositions for use in generating induced hepatocytes by reprogramming non-hepatocyte cells. | 2014-03-27 |
20140087417 | Personal Care Products with Visual Indicator of Vaginitis - There is provided a personal care product having a body side liner, a baffle and an indicator strip with two ends. The indicator has an amine sensitive dye near at least one end. The indicator extends from the target area just below the liner to just above the baffle such that the dye deposit is visible to an unaided eye. The dye changes color in the presence of amines which are characteristic of infection, thus alerting the user to the possibility of infection. Such an indicator placed in a feminine hygiene pad, for example, may be useful in the diagnosis of vaginitis. | 2014-03-27 |
20140087418 | ORGANIC-INORGANIC NANOFLOWERS, THEIR SYNTHESIS AND USE - Organic-inorganic nanoflowers, methods of synthesis, and uses of the nanoflowers are described. It has been found that organic-inorganic nanoflowers can be grown in the presence of a solid substrate containing copper without the requirement for added copper ion. The method includes exposing bacteria to a solid substrate containing copper in the presence of an aqueous solution that contains phosphate ions. The aqueous solution can additionally contain chloride ions, similar to that of a phosphate-buffered saline composition. The solid substrate can be an alloy of copper and tin, and the substrate can have phosphorus incorporated into it. | 2014-03-27 |
20140087419 | METHOD FOR MAKING BIOLOGICAL MATERIAL TRANSPARENT AND USE THEREOF - A method for making a biological material transparent according to the present invention includes: a first permeation step of causing a first solution to permeate into a biological material, the first solution containing at least one compound selected from the group consisting of urea and urea derivatives at a predetermined concentration; and then a second permeation step of causing a second solution to permeate into the biological material, the second solution containing at least one compound selected from the group consisting of urea and urea derivatives at a concentration higher than the concentration of the at least one compound contained in the first solution. | 2014-03-27 |
20140087420 | NOVEL MICROORGANISM RHIZOBIUM SP. KB10 HAVING PROPERTIES OF PROMOTING GROWH OF BOTRYOCOCCUS BRAUNII AND INCREASING FATTY ACID CONTENT - The present invention relates to | 2014-03-27 |
20140087421 | NOVEL 7Beta-HYDROXYSTEROID DEHYDROGENASE MUTANTS AND PROCESS FOR THE PREPARATION OF URSODEOXYCHOLIC ACID - The invention relates to novel 7β-hydroxysteroid dehydrogenase mutants, to the sequences which encode these enzyme mutants, to processes for the preparation of the enzyme mutants and to their use in enzymatic reactions of cholic acid compounds, in particular in the preparation of ursodeoxycholic acid (UDCS). The invention also relates to novel processes for the synthesis of UDCS using the enzyme mutants; and to the preparation of UDCS using recombinant, multiply-modified microorganisms. | 2014-03-27 |
20140087422 | Nucleic acids related to fusion proteins - The present invention concerns a family of nucleic acids, polypeptides and cloning vectors which direct expression of fusion proteins that can mimic aggregated IgG (AIG) and immune complex function with respect to their interactions with FcγR and which allow for the inclusion and targeting of a second protein domain to cells expressing FcγR. This was accomplished by expressing multiple linear copies of the hinge and CH2 domains (HCH2) of human IgG | 2014-03-27 |
20140087423 | Method for Controlling the Main Complex N-Glycan Structures and the Acidic Variants and Variability in Bioprocesses Producing Recombinant Proteins - The present invention relates to a method of controlling quality and quantity of posttranslational modification of a recombinantly produced polypeptide/protein (glycoprotein), wherein the posttranslational modification affects the glycosylation profile and/or the acidic variants profile, as manifested in CEX profiles, wherein the polypeptide/protein (glycoprotein) production is in eukaryotic host cells, the method comprising the following steps: a) cultivating the eukaryotic cells in a suitable medium under conditions which allow the expression of the polypeptide/protein, wherein the content of the dissolved CO | 2014-03-27 |
20140087424 | Process for Cell Culturing by Continuous Perfusion - The invention relates to a process for the culturing of cells by continuous perfusion culturing of a cell culture comprising cell culture medium and cells, wherein cell culture medium is added to the cell culture, the cell culture is circulated over a filter module comprising hollow fibers resulting in an outflow of liquid having a lower cell density than the cell culture and the flow within the filter module is an alternating tangential flow. Preferably, culture medium is added at a particular perfusion rate and/or biomass is removed form the culture at least once. The method is especially suitable for the culturing of aggregating cells. The invention also relates to such a process wherein a biological substance, preferably an antibody, is produced by the cells, which biological substance may be further purified in downstream processing. | 2014-03-27 |
20140087425 | METHODS FOR PREPARING PURIFIED LIPOPEPTIDES - The present invention relates to crystalline and crystal-like forms of lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention relates to methods of purifying lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention also relates to pharmaceutical compositions comprising the purified form of the lipopeptide and methods of using these compositions. | 2014-03-27 |
20140087426 | TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES (TALENS) - This application provides transcription activator-like effector nucleases (TALENs), polynucleotide sequences encoding the TALENs, expression cassettes for producing TALENs to target cleavage of nucleic acids, and methods of producing and using the TALENs. | 2014-03-27 |
20140087427 | dsRNA ENDORIBONUCLEASES - The invention relates to a new double-stranded RNA endoribonuclease, its derivative and/or variant, which has a loop locating in and interacting with the major groove of the double-stranded RNA, exhibiting sequence specific properties in the double-stranded RNA cleavage. | 2014-03-27 |
20140087428 | Microorganisms And Methods For Producing Substituted Phenols - The present invention is concerned with methods for producing vanillin, feroyl-CoA, ferulic acid, coniferyl aldehyde and/or coniferyl alcohol. Also, the invention relates to microorganisms useful in such production method, and to the construction of such microorganisms. | 2014-03-27 |
20140087429 | ALPHA-AMYLASE BLEND FOR STARCH PROCESSING AND METHOD OF USE THEREOF - The present disclosure relates to an enzyme blend comprising a low pH, thermostable alpha-amylase and a | 2014-03-27 |
20140087430 | SINGLE PH PROCESS FOR STARCH LIQUEFACTION AND SACCHARIFICATION FOR HIGH-DENSITY GLUCOSE SYRUPS - Embodiments of the present disclosure relate to a process for producing downstream products, such as high-density glucose syrups and high-glucose fermentation feedstock, from a starch-containing substrate without a pH adjustment before the saccharification step. The saccharification is effectively catalyzed by a glucoamylase at a pH in the range of 5.2 to 5.6. | 2014-03-27 |
20140087431 | GLUCOSYLTRANSFERASE ENZYMES FOR PRODUCTION OF GLUCAN POLYMERS - Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan. | 2014-03-27 |
20140087432 | METHODS FOR CONDITIONING PRETREATED BIOMASS - Methods for producing ethanol from cellulosic biomass and, in particular, methods for conditioning pretreated biomass are disclosed. In some embodiments, pretreated biomass is contacted with a cooling fluid in a flash vessel to cool the biomass. The amount of alkaline solution contacted with the biomass may be based on the pH of partially hydrolyzed pretreated biomass in a liquefaction bioreactor. | 2014-03-27 |
20140087433 | Processing Biomass - Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce an intermediate or product, e.g., by fermentation. | 2014-03-27 |
20140087434 | METHOD FOR PRODUCING AQUEOUS ACRYLAMIDE SOLUTION - There is provided a method for producing an aqueous acrylamide solution by reacting a composition including acrylonitrile with water to produce acrylamide, in which the composition including acrylonitrile includes 3 to 15 mg of propionitrile per 1 kg of the total weight of the composition including acrylonitrile. According to the present invention, a production method with which it is possible to suppress acrylamide polymerization without lowering quality and thereby obtain a stable aqueous acrylamide solution can be provided. | 2014-03-27 |
20140087435 | Novel Microbial Biocatalysts That Enables Use Of Cellodextrin As Biofuel - The present disclosure provides genetically engineered biocatalysts which enable intracellular assimilation of cellodextrin. The genetically engineered biocatalyst co-expresses a cellodextrin phosphorylase (CDP) gene and a cellobiose phosphorylase (CBP) gene. Further, the genetically engineered biocatalyst includes a first synthetic promoter used to express the cellodextrin phosphorylase (CDP) gene and a second synthetic promoter used to express the cellobiose phosphorylase (CBP) gene. Furthermore, the genetically engineered biocatalyst expresses one or more cellodextrin permeases. The intracellular assimilation includes hydrolysis and phosphorolysis mechanism. Further provided are methods of using the genetically engineered biocatalysts to generate various useful end-products including alcohol and lactic acid. | 2014-03-27 |
20140087436 | AUTOTROPHIC HYDROGEN BACTERIA AND USES THEREOF - In an aspect, the invention relates to compositions and methods production of n-butanol by aerobic hydrogen bacteria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 2014-03-27 |
20140087437 | PROCESS FOR THE CRYSTALLISATION OF A WATER-SOLUBLE COMPOUND - A process for the crystallisation of a water-soluble compound from a solution of water and a solvent is provided. A process for the manufacture of crystalline sucrose from sugar palm juice or sucrose-containing biomass comprising such crystallisation process is also disclosed. | 2014-03-27 |
20140087438 | ISOLATED YEAST STRAIN HAVING HIGH XYLOSE CONSUMPTION RATE AND PROCESS FOR PRODUCTION OF ETHANOL USING THE STRAIN - The invention utilizes cloning and transformation techniques in combination with mutation and strain taming techniques to obtain yeasts having high xylose consumption rate and ethanol yield. The cloning and transformation used in the invention are to transform xylose metabolism genes to yeasts to solve the problem that some yeast strains cannot utilize xylose to produce ethanol. The mutation and strain taming used in the invention are to increase xylose consumption rate and ethanol yield to solve the problem of low rate and yield. By combining the above-mentioned technical means, the invention unexpectedly obtain a mutant having high xylose consumption rate and ethanol yield. | 2014-03-27 |
20140087439 | COMPLEX AND USES THEREOF - The present invention provides a complex of a metal reducing substance and a culture medium component, which is produced in the culturing process of reducing bacteria and the use thereof. The complex of the present invention is a complex produced in the culturing process of reducing bacteria and a compound of a metal reducing substance and a culture medium component. The complex is an adsorbent for quickly and efficiently adsorbing ionic substances present in a solution, and also functions as a reducing agent for reducing specific precious metal ions or platinum-group metal ions. | 2014-03-27 |
20140087440 | MAGNETIC THREE-DIMENSIONAL CELL CULTURE APPARATUS AND METHOD - A culture apparatus and method for growing cells and tissue in a three-dimensional configuration harnesses magnetic, paramagnetic, ferromagnetic and diamagnetic forces. The cells or tissue are grown with magnetized core particles and are suspended via magnetic forces in a native, non-restricted, three-dimensional configuration while being maintained in a normal gravity (1 g) growth environment in the absence of rotational alteration of the gravity vector. | 2014-03-27 |
20140087441 | NOVEL APPLICATION OF FIBRINOGEN-420 AND ITS ACTIVE DOMAIN - The invention discloses a novel application of fibrinogen-420 and its active domain (alpha EC domain), and a separate alpha EC domain protein has the same or similar function with fibrinogen-420. Fibrinogen-420 and its active domain can be widely used in inhibiting protein aggregation, helping protein refolding, drugs which can prevent and/or treat protein conformation disease, detecting denatured protein in quality control and protect protein from denaturation. | 2014-03-27 |
20140087442 | GLUCOAMYLASE VARIANTS - The present invention relates to glucoamylase variants. In particular, the invention relates to variants in the starch binding domain (SBD) of a glucoamylase. The invention also relates to variants having altered properties (e.g., improved thermostability and/or increased specific activity) as compared to a corresponding parent glucoamylase. The present invention also provides enzyme compositions comprising the variant glucoamylases; DNA constructs comprising polynucleotides encoding the variants; and methods of producing the glucoamylase variants in host cells. | 2014-03-27 |
20140087443 | OVER EXPRESSION OF FOLDASES AND CHAPERONES IMPROVES PROTEIN PRODUCTION - The present teachings provide methods for increasing protein secretion, e.g., chymosin in filamentous fungi by co-expressing certain chaperone(s) and/or foldase(s). The present teachings also provide filamentous fungi containing certain chaperone(s) and/or foldase(s) and a protein of interest for increased secretion. | 2014-03-27 |
20140087444 | Proviral Plasmids and Production of Recombinant Adeno-Associated Virus - Proviral plasmids contain a modular gene expression cassette with one or a combination of (i) a wildtype 5′ AAV2 ITR sequence flanked by unique restriction sites that permit ready removal or replacement of said ITR; (ii) a promoter flanked by unique restriction sites that permit ready removal or replacement of the entire promoter sequence; (iii) a polylinker sequence that permits insertion of a gene coding sequence without modification thereof, wherein the gene is operatively linked to, and under the regulatory control of, the aforementioned promoter; (iv) a bovine growth hormone polyadenylation sequence flanked by unique restriction sites that permit ready removal or replacement of said polyA sequence; and (v) a wildtype 3′ AAV2 ITR sequence flanked by unique restriction sites that permit ready removal or replacement of the 3′ ITR. These plasmids enable rapid manipulation of the components of the cassette, e.g., rapid mutation and/or replacement of any component, and thereby increase the efficiency of recombinant viral vector, e.g., rAAV, production. | 2014-03-27 |
20140087445 | METHOD OF MAKING LIGAND FUNCTIONALIZED SUBSTRATES - Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed. | 2014-03-27 |
20140087446 | COMPOSITIONS AND METHODS FOR CULTURING SPIROCHETES - The present invention relates to methods for culturing spirochetes, in particular | 2014-03-27 |
20140087447 | Cell Modeling of Heme Deficiency using Ferrochelatase Mutations - Provided herein, is a means for development of ferrochelatase variants with improved tolerance towards N-methyl protoporphyrin. Also disclosed are cell assay systems utilizing the variants, as the variants would confer resistance to N-methyl protoporphyrin inhibition and thereby keep heme synthesis uninterrupted. The variants contain loop mutations that affect the NMPP-ferrochelatase interaction, and different degrees of NMPP tolerance are obtained with the introduction of loop mutations in wild-type ferrochelatase. Also disclosed is kinetic mechanism of inhibition of ferrochelatase by NMPP, using the disclosed variants whose mutations in the “porphyrin-interacting loop” motif weakened the potency of NMPP as an inhibitor. | 2014-03-27 |
20140087448 | PROCESS FOR OBTAINING A BROWN ALGAE LYOPHILISATE, AND COSMETIC PREPARATIONS THEREOF - A process for obtaining a freeze-dried product of gametophytes cells of brown algae, and a cosmetic preparation for tropical use including the freeze-dried product of gametophytes cells of brown algae obtained. | 2014-03-27 |
20140087449 | Method for Providing DNA Fragments Derived from an Archived Sample - Aspects of the present invention relate to compositions and methods for providing DNA fragments from an archived sample (e.g., paraffin-embedded and/or fixed-tissue biopsies, etc.). Particular aspects provide methods whereby high yields of DNA are isolated as well as a substantial portion of the DNA consists of long DNA fragments, and where the isolated genomic DNA is free of associated or cross-linked contaminants like proteins, peptides, amino acids or RNA. The methods are facile, cost-effective, and are characterized by high reproducibility and reliability. Particular aspects provide methods for providing DNA fragments derived from an archived sample, wherein the yield of DNA before, for example, an amplification step is at least 20%, and amplicons up to a length of about 1,000 base pairs are amplifiable. | 2014-03-27 |
20140087450 | DEPOSITION DEVICE, AND COLLECTION DEVICE | 2014-03-27 |
20140087451 | ACOUSTIC WAVE (AW) SENSING DEVICES USING LIVE CELLS - In one embodiment according to the invention, there is provided a method of sensing a response of a living cell or virus to a change in conditions. The method comprises applying an essentially constant external electromotive force that causes oscillation of an acoustic wave device at essentially constant amplitude and frequency under steady state conditions. The acoustic wave device has attached at least one living cell or virus. A combined oscillating system including the acoustic wave device and the living cell or virus exhibits a fundamental frequency and at least one harmonic frequency of the combined oscillating system. The living cell or virus is exposed to a change in an environmental condition while oscillating the combined oscillating system under the essentially constant external electromotive force, whereby a response of the living cell or virus to the change in environmental condition will be indicated by a change in at least one of frequency and amplitude of the oscillation of at least one harmonic frequency of the combined oscillating system. | 2014-03-27 |
20140087452 | IN-VITRO CONTACT LENS TESTING - Contact lens testing apparatuses and method for testing contact lenses for analytes are presented. In an aspect, a device is provided that includes a housing configured to hold one or more contact lenses, and a testing compartment provided within the housing and comprising a reagent, the reagent configured to facilitate a chemical reaction in response to the existence of a predetermined biomarker disposed on or within a contact lens placed in the testing compartment, wherein the chemical reaction produces a known result related to state information of an individual from which the biomarker was generated. | 2014-03-27 |
20140087453 | MICROPARTICLE ANALYSIS APPARATUS AND MICROPARTICLE ANALYSIS METHOD - There is provided a microparticle analysis apparatus including a light detection unit configured to detect forward-scattered light generated from a microparticle that is an analysis target. The light detection unit includes a circuit having a high-pass filter that removes low frequency noise included in light entering the light detection unit and switches to the high-pass filter according to a predetermined frequency of the forward-scattered light. | 2014-03-27 |
20140087454 | Hepatic Lobule-Like Bioreactor - The present invention provides a hepatic lobule-like bioreactor. The bioreactor includes a nanofiber scaffold enclosed within a housing. An intrahepatic fibrous vascular network, a bile capillary network, upper hepatic bile ducts, lower hepatic bile ducts, a common bile duct connecting the upper and the lower hepatic bile ducts, and collagen fibrous microchannels for hepatocytes surrounded by the bile capillary network are distributed throughout the nanofiber scaffold. Bile capillaries in the bile capillary network are provided with two or more inlet ports for biliary epithelial cells. The collagen fibrous microchannels for hepatocytes are provided with two or more inlet ports for hepatocytes. The intrahepatic vascular network is provided with a liquid inlet port and a liquid outlet port. These ports extend through the housing | 2014-03-27 |
20140087455 | Cell Culture Device and Transport Device - The present invention provides a carrier device including a culture vessel and a flow channel, which have a closed structure, for supplying cell liquid or a culture medium into the flow channel; and a method of aseptically injecting liquid, such as the cell or the culture medium, into the culture vessel and the flow channel. The present invention provides a carrier jig | 2014-03-27 |
20140087456 | Isolating Target Cells From A Biological Fluid - A micro-fluidic device operable to isolate target cells from a biological fluid comprises: an inlet operable to receive the biological fluid, the biological fluid comprising target cells and other components; a waste outlet operable to receive at least the other components of the biological fluid; a plurality of parallel arrays of cell isolation wells coupling the inlet with the waste outlet, each parallel array of cell isolation wells supporting a flow of the biological fluid from the inlet to the waste outlet in response to a pressure differential thereacross, each array of cell isolation wells comprising a plurality isolation wells, each isolation well being dimensioned to mechanically trap the target cells therein whilst permitting flow of other components of the biological fluid; and at least one pressure maintenance structure operable to assist in maintaining a predetermined pressure differential across each of the plurality of parallel arrays of cell isolation wells. | 2014-03-27 |
20140087457 | GAS SPARGERS AND RELATED CONTAINER SYSTEMS - A container system includes a bag having of one or more sheets of flexible polymeric material, the bag having an interior surface at least partially bounding a chamber that is adapted to hold a fluid. A sparger is secured to the interior surface of the bag so that a compartment is formed between the interior surface of the bag and the sparger. At least a portion of the sparger includes a sparging sheet formed from a flexible sheet of a gas permeable material. A tubular port or tube is coupled with the bag so that a passage bounded by the tubular port or tube communicates with the compartment. | 2014-03-27 |
20140087458 | METHODS AND COMPOSITIONS FOR PRODUCING VITAMIN K DEPENDENT PROTEINS - The present invention relates to methods and compositions for improving the productivity of recombinant vitamin K dependent protein expression in host cells. | 2014-03-27 |
20140087459 | Expansion Medium for CD34-Negative Stem Cells - This invention provides a cell growth medium comprising (a) a human platelet lysate free of solid matter greater than 0.22 μm in diameter; (b) a human fresh frozen plasma (FFP) filtrate free of solid matter greater than 0.22 μm in diameter; (c) heparin; (d) L-glutamine; and (e) a serum-free, low glucose medium suitable for mammalian cell growth, wherein the cell growth medium permits the expansion of human CD34 | 2014-03-27 |
20140087460 | INDUCTION OF HUMAN EMBRYONIC STEM CELL DERIVED CARDIAC PACEMAKER OR CHAMBER-TYPE CARDIOMYOCYTES BY MANIPULATION OF NEUREGULIN SIGNALING - The present invention is directed to methods of producing cardiomyocytes having a nodal/pacemaker phenotype and cardiomyocytes having an atrial/ventricular phenotype. Isolated populations of nodal/pacemaker and atrial/ventricular cardiomyocytes are also disclosed. Methods of treating a subject having cardiac arrhythmia and a subject in need of cardiac tissue repair using the isolated populations of nodal/pacemaker cardiomyocytes and atrial/ventricular cardiomyocytes, receptively, are also disclosed. | 2014-03-27 |
20140087461 | CARBON-NANOTUBE MODULATION OF MYOCYTE CELLS - Embodiments include compositions of carbon nanotubes complexed with myocyte cells. Embodiments also include methods for making compositions of carbon nanotubes, and methods for modulating the electrophysical, proliferative, and viability potential of myocytes. | 2014-03-27 |
20140087462 | METHOD FOR POLYCLONAL STIMULATION OF T CELLS BY FLEXIBLE NANOMATRICES - The present invention provides a method polyclonal stimulation of T cells, the method comprising contacting a population of T cells with a nanomatrix, the nanomatrix comprising a) a flexible matrix, wherein said matrix is of polymeric material; and b) attached to said polymeric flexible matrix one or more polyclonal stimulatory agents which provide activation signals to the T cells; thereby activating and inducing the T cells to proliferate; wherein the nanomatrix is 1 to 500 nm in size. At least one first and one second stimulatory agents are attached to the same or to separate flexible matrices. If the stimulatory agents are attached to separate beads, fine-tuning of nanomatrices for the stimulation of the T cells is possible. | 2014-03-27 |
20140087463 | OPTICAL CONTROL OF CELL SIGNALING - The present invention discloses methods of spatiotemporally controlling G protein signaling in a cell using an artificial optical input. Also disclosed are methods of manipulating cell behavior that is controlled by asymmetrical G protein signaling in a cell. | 2014-03-27 |
20140087464 | MULTIPOTENT NEURAL CELLS - The inventions disclosed herein are based on the identification of novel cell populations derived from human embryonic stem cells and other pluripotent cells. The inventive cell populations may be used for cell therapies for the treatment of various neurological diseases and as substrates in pharmacological assays. | 2014-03-27 |
20140087465 | CELL CULTURE METHOD AND CELL CULTURE KIT - Provided is a means suitable for mass culture of adherent cells and which allows easy and safe collection of the cultured adherent cells. A cell culture kit has a culture bag having flexibility, such a level of hydrophilicity that the culture of adherent cells can be achieved, and permeability into a bag shape and which is filled with a culture medium; a dissociation solution bag filled with a dissociation solution containing a metal chelating agent or ornithine or a derivative thereof, and a solution sending circuit or a derivative thereof, and a solution sending circuit which connects the culture bag and the dissociation solution bag to each other and can send the dissociation solution from the dissociation solution bag to the culture bag. | 2014-03-27 |
20140087466 | MICRO BLOOD VESSELS AND TISSUE DUCTS - A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves. | 2014-03-27 |
20140087467 | FERROMAGNETIC CELL AND TISSUE CULTURE MICROCARRIERS - A porous, collagen coated, ferromagnetic cell culture microcarrier, which is suitable for in vitro cell and tissue culture and which facilitates 3D multicellular construct generation. Also provided is a method for creating batches of microcarriers which have inserted within them magnetite (Fe3O4) in the presence of collagen, thus creating a microcarrier which becomes magnetic in nature when placed in a the presence of a magnetic field and which facilitates cellular adherence (via the collagen coating) for 3D construct development. | 2014-03-27 |
20140087468 | METHODS AND COMPOSITIONS FOR GENERATING AN IMMUNE RESPONSE BY INDUCING CD40 AND PATTERN RECOGNITION RECEPTOR ADAPTERS - Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible pattern recognition receptor adapter, or adapter fragment, and CD40 activity. Also provided are nucleic acid compositions comprising sequences coding for chimeric proteins that include an inducible CD40 peptide and an inducible pattern recognition receptor adapter or adapter fragment. | 2014-03-27 |
20140087469 | SYSTEM AND PROCESS FOR GENETIC AND EPIGENETIC TREATMENT - Transplantation of total or partial organs or tissues from one person to another creates severe immunologic problems and does not obtain a genetic rejuvenation, for example, of half the biological age of the donor's selected tissue. The invention permits, without a return to an embryonic stage, to develop an autologous and genetic rejuvenated (AGR) tissue that can be grafted without graft rejection in the donor's body. In order to reconstitute an organ, every tissue should be treated separately and re-assembled afterwards in a cellular culture. Thus, it becomes possible to repair damaged tissues, such as: retina, myocardium, lung, kidney, hepatic, pancreas, osteoporosis, etc. using their own cells that receive a genetic rejuvenation and that remain adult and immediately functional after their implantation. | 2014-03-27 |
20140087470 | REVERSIBLE IMMORTALIZATION - A gene complex for reversibly immortalizing cells contains an immortalizing gene region, which possesses at least a resistance gene, an immortalizing gene and, preferably, a suicide gene, and also two sequences which flank the gene region and which function as recognition sites for homologous intramolecular recombination, and at least one promoter located upstream of the gene region. A gene complex for imnomodulating cells contains a first immunomodulating gene region, whose expression inhibits the function of MHC I molecules, a second immunomodulating gene region, whose expression leads to the inactivation of natural killer cells, and a resistance gene. A method for obtaining cells involves preparing organ-related cells which are immortalized by transferring the first gene complex and immunomodulated by transferring the second gene complex. After the immortalized cells have been expanded, the immortalization is reversed. | 2014-03-27 |
20140087471 | METHOD FOR DETECTING URINE ODOR FROM AIR CONDITIONER, REPRODUCING URINE ODOR AND PREPARING CORRESPONDING URINE ODOR COMPOSITION - Disclosed herein is a method for identifying the compounds contributing to urine odor emitting from an air conditioner, a method for artificially reproducing the detected urine odor, and preparing a corresponding urine odor composition. Through the analysis method of the present invention, the compounds contributing to the urine odor emitted from an air conditioner may be identified and quantified. The detected urine odor may be reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced urine odor may provide meaningful data required for development of an apparatus and a method for removing specific odor. | 2014-03-27 |
20140087472 | SAMPLE ANALYZER AND SAMPLE ANALYZING METHOD - Disclosed is a sample analyzer comprising: a transporting part configured to transport a sample rack holding one or more samples; a measuring part configured to perform a measurement on the sample of the transported sample rack; and a controller; wherein the controller is programmed to perform an analysis of a predetermined item that requires at least first and second measurement results derived respectively from first and second samples obtained from the same subject and preprocessed in different ways, if a measurement of the predetermined item is requested and a set of first and second samples obtained from the same subject and preprocessed in different ways are transported to the measuring part, the controller controls the measuring part to perform measurements on both of the first and second samples to derive the first and second measurement results and processes them to generate an analysis result of the predetermined item. | 2014-03-27 |
20140087473 | METHOD OF MARKING HYDROCARBON LIQUIDS - A method of marking a hydrocarbon liquid includes the step of | 2014-03-27 |
20140087474 | APPARATUS AND METHODS FOR PERFORMING OPTICAL NANOPORE DETECTION OR SEQUENCING - Methods and systems for detecting or sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. Optical sequencing of a molecule may be performed utilizing an optical or photon detector operated in time delayed integration mode. In certain variations, the translocation rate of molecules through a, pore, nanopore or channel may be controlled or reduced by increasing the diameter of the molecules to allow for molecule detection or sequencing by optical or electrical detection. In certain variations, a plurality or an array of, pores, nanopores, or channels may be utilized to optically detect a plurality of molecules. | 2014-03-27 |
20140087475 | METHOD FOR DETECTING SOUR ODOR FROM AIR CONDITIONER, REPRODUCING SOUR ODOR AND PREPARING CORRESPONDING SOUR ODOR COMPOSITION - Disclosed herein is a method for identifying compounds contributing to a sour odor emitting from an air conditioner, a method for artificially reproducing the detected sour odor and preparing a corresponding sour odor composition. Through the analysis method of the present invention, the compounds contributing to the sour odor emitted from an air conditioner may be identified and quantified. The detected sour odor may be reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced sour odor may provide meaningful data required for development of an apparatus and a method for removing specific odors. | 2014-03-27 |
20140087476 | OPTICAL SENSOR FOR BROMIDE ION - Methods and systems to determine a concentration of bromide ions in an aqueous sample are disclosed. The method involves the oxidation of bromide ions to bromine, followed by bromination of a colored or fluorescent reporter compound which may be detected by spectrophotometric means. The relative change in color or fluorescence upon bromine binding to the reporter compound may then be used to determine a quantitative concentration of bromide ions in the sample. The system utilizes a photocatalytic coating in a sample chamber, a source of reporter compound in fluid communication with the sample chamber, light sources that may activate the photocatalyst and excite the reporter compound, an optical detection unit capable of receiving a light signal from the second light source after it has passed through the sample chamber, and various pumps, valves or injection syringes that regulate the flow of sample and reporter compound into and out of the sample chamber. | 2014-03-27 |
20140087477 | Ion Mobility Spectrometer Which Controls Carrier Gas Flow to Improve Detection - IMS apparatus has an inlet with a preconcentrator opening into a reaction region where analyte molecules are ionized and passed via a shutter to a drift region for collection and analysis. A pump and filter arrangement supplies a flushing flow of clean gas to the housing in opposition to ion flow. A pressure pulser connects with the housing and is momentarily switched to cause a short drop in pressure, in the housing to draw in a bolus of analyte sample from the preconcentrator. Just prior to admitting a bolus of sample, the pump is turned off so that the flushing flow drops substantially to zero, thereby prolonging the time the analyte molecules spend in the reaction region. | 2014-03-27 |
20140087478 | MASS SPECTROMETER INTERFACE - A mass spectrometer interface, having improved sensitivity and reduced chemical background, is disclosed. The mass spectrometer interface provides improved desolvation, chemical selectivity and ion transport. A flow of partially solvated ions is transported along a tortuous path into a region of disturbance of flow, where ions and neutral molecules collide and mix. Thermal energy is applied to the region of disturbance to promote liberation of at least some of the ionized particles from any attached impurities, thereby increasing the concentration of the ionized particles having the characteristic m/z ratios in the flow. Molecular reactions and low pressure ionization methods can also be performed for selective removal or enhancement of particular ions. | 2014-03-27 |
20140087479 | LIQUID REAGENT STORAGE AND OPERATION OF ANALYTICAL DEVICES - Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved. | 2014-03-27 |
20140087480 | Methods and Compositions for Assaying a Sample for an Aggregant - This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein. | 2014-03-27 |
20140087481 | SCD FINGERPRINTS - The present invention relates to the use of cluster of differentiation (CD) molecules in detecting the presence and progression of one or more disease states in an individual. In particular it relates to the use of profiles of shed CD (sCD) molecules in detecting and assessing the progression of one or more disease states in an individual. Further uses of sCD profiles according to the present invention are also described. | 2014-03-27 |
20140087482 | METHOD FOR DETECTING TARGET PARTICLES - The present invention provides a method for detecting a target particle, comprising: (a) concentrating a test sample so as to enhance the concentration of target particles in the test sample, (b) preparing a sample solution containing the test sample concentrated in (a) and a luminescent probe that binds to the target particle, and allowing the target particle and the luminescent probe to bind in the sample solution, and (c) counting the number of target particles bound to the luminescent probe present in the sample solution according to a scanning molecule counting method, wherein the luminescence properties of the released light differ between the state in which the luminescent probe is bound to the target particle and the state in which the luminescent probe is present alone. | 2014-03-27 |
20140087483 | MANUFACTURING METHOD OF MAGNETORESISTIVE EFFECT ELEMENT AND MANUFACTURING APPARATUS OF MAGNETORESISTIVE EFFECT ELEMENT - According to one embodiment, a manufacturing method of a magnetoresistive effect element includes forming a laminated structure on a substrate, the laminated structure including a first magnetic layer having a variable magnetization direction, a second magnetic layer having an invariable magnetization direction, and a non-magnetic layer between the first and second magnetic layers, forming a first mask layer having a predetermined plane shape on the laminated structure, and processing the laminated structure based on the first mask layer by using an ion beam whose solid angle in a center of the substrate is 10° or more. | 2014-03-27 |
20140087484 | METHOD FOR FABRICATING A DAMASCENE SELF-ALIGNED FERRORELECTRIC RANDOM ACCESS MEMORY (F-RAM) WITH SIMULTANEOUS FORMATION OF SIDEWALL FERROELECTRIC CAPACITORS - A method for fabricating a non-volatile, ferroelectric random access memory (F-RAM) device is described. In one embodiment, the method includes forming an opening in an insulating layer over a surface of a substrate, and forming bottom electrode spacers proximal to sidewalls of the opening. Next, a ferroelectric dielectric layer is formed in the opening over the surface of the substrate and between the bottom electrode spacers, and a pair of top electrodes is formed within the opening comprising first and second side portions displaced laterally from respective ones of the bottom electrode spacers by the ferroelectric dielectric layer. | 2014-03-27 |
20140087485 | SEMICONDUCTOR DEVICE MANUFACTURING METHOD - According to one embodiment, a method for manufacturing a semiconductor device is disclosed. The method includes forming a first magnetic film containing boron, forming a second magnetic film free from boron, above the first magnetic film. The method further includes selectively etching the second magnetic film with respect to the first magnetic film using plasma of etching gas which contains oxygen and hydrogen and which is free from halogen. | 2014-03-27 |
20140087486 | METHOD FOR ETCHING WITH CONTROLLED WIGGLING - A method for etching trenches in an etch layer disposed below a patterned organic mask is provided. The patterned organic mask is treated, comprising flowing a treatment gas comprising H | 2014-03-27 |
20140087487 | METHOD FOR REPAIRING SOLAR CELL MODULE - A method for repairing a solar cell module includes the following steps. A solar cell module, which is provided, includes a first and a second solar cell serially connected. A first terminal is electrically connected to a first electrode layer of the first solar cell. A second terminal is electrically connected to a second electrode layer of the second solar cell. A polarity of the first electrode layer is the same as that of the second electrode layer. A biased voltage signal is generated and transmitted to the first solar cell and the second solar cell through the first terminal and the second terminal. The biased voltage signal includes a forward biased voltage part greater than zero and a reversed biased voltage part smaller than zero. The voltage value of the reversed biased voltage part is increasingly decreased in a step-like manner as time goes by. | 2014-03-27 |
20140087488 | SHOWERHEAD ELECTRODE ASSEMBLY IN A CAPACITIVELY COUPLED PLASMA PROCESSING APPARATUS - A showerhead electrode assembly for use in a capacitively coupled plasma processing apparatus comprising a heat transfer plate. The heat transfer plate having independently controllable gas volumes which may be pressurized to locally control thermal conductance between a heater member and a cooling member such that uniform temperatures may be established on a plasma exposed surface of the showerhead electrode assembly. | 2014-03-27 |
20140087489 | BOTTOM AND SIDE PLASMA TUNING HAVING CLOSED LOOP CONTROL - An apparatus for plasma processing a substrate is provided. The apparatus comprises a processing chamber, a substrate support disposed in the processing chamber, and a lid assembly coupled to the processing chamber. The lid assembly comprises a conductive gas distributor coupled to a power source. A tuning electrode may be disposed between the conductive gas distributor and the chamber body for adjusting a ground pathway of the plasma. A second tuning electrode may be coupled to the substrate support, and a bias electrode may also be coupled to the substrate support. | 2014-03-27 |
20140087490 | Method and Apparatus for Improving Particle Performance - A method for combinatorially processing a substrate is provided. The method includes providing a substrate disposed on a substrate support. The method further includes rigidly locking a top portion of a sleeve to a bottom portion of a process head of a combinatorial processing device, where the combinatorial processing device is operable to concurrently process different regions of the substrate differently. The method includes raising the substrate and the substrate support to contact a sealing surface of the sleeve with a surface of the substrate and combinatorially processing the different regions of the substrate. | 2014-03-27 |
20140087491 | WAFER LEVEL BONDING METHOD FOR FABRICATING WAFER LEVEL CAMERA LENSES - A wafer-level bonding method for fabricating wafer level camera lenses is disclosed. The method includes: providing a lens wafer including lenses arranged in an array and a sensor wafer including sensors arranged in an array; measuring and analyzing an FFL of each lens to obtain a corresponding FFL compensation value for each lens; forming a thin transparent film (TTF) on each sensor of the sensor wafer, and the thickness of TTF is determined by the FFL compensation value of the corresponding lens; aligning and bonding the lens wafer with the sensor wafer having TTFs formed thereon. Since the focal length of each lens is adjusted to compensate the FFL of the lens by adding a TTF of transparent optical material with an index of refraction that is similar to the index of refraction of the sensor cover glass, the FFL variation of each camera lens can be reduced. | 2014-03-27 |
20140087492 | Exclusion Zone for Stress-Sensitive Circuit Design - A semiconductor structure less affected by stress and a method for forming the same are provided. The semiconductor structure includes a semiconductor chip. Stress-sensitive circuits are substantially excluded out of an exclusion zone to reduce the effects of the stress to the stress-sensitive circuits. The stress-sensitive circuits include analog circuits. The exclusion zone preferably includes corner regions of the semiconductor chip, wherein the corner regions preferably have a diagonal length of less than about one percent of the diagonal length of the semiconductor chip. The stress-sensitive analog circuits preferably include devices having channel lengths less than about five times the minimum channel length. | 2014-03-27 |
20140087493 | METHOD OF MANUFACTURING OPTICAL MODULATOR, AND OPTICAL MODULATOR - A method for manufacturing an optical modulator having a laser diode section and an EAM section. LD growth layers which are semiconductor layers for manufacturing the laser diode section, are formed on a semiconductor substrate. An EAM absorption layer for forming the EAM section is then formed on the semiconductor substrate. The photoluminescent wavelength of the EAM absorption layer is then measured. The LD growth layers are then etched to form a stripe structure section. The width of the stripe structure section is determined such that the difference between the lasing wavelength of the LD section and the photoluminescent wavelength of the EAM section is close to a design value. | 2014-03-27 |
20140087494 | DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME - A display device and a method of manufacturing the same. In one embodiment, a display device includes a substrate having a pixel region, a transistor region and a capacitor region, a transistor arranged within the transistor region of the substrate and a capacitor arranged within the capacitor region of the substrate, wherein the capacitor includes a lower electrode arranged on the substrate, a gate insulating layer arranged on the lower electrode and an upper electrode arranged on the gate insulating layer and overlapping the lower electrode, the upper electrode includes a first conductive layer and a second conductive layer arranged on the first conductive layer, wherein the first conductive layer is opaque. | 2014-03-27 |
20140087495 | ORGANIC LIGHT EMITTING ELEMENT AND METHOD OF MANUFACTURING THE SAME - An organic light emitting element includes an organic light emitting diode formed on a substrate, coupled to a transistor including a gate, a source and a drain and including a first electrode, an organic thin film layer and a second electrode; a photo diode formed on the substrate and having a semiconductor layer including a high-concentration P doping region, a low-concentration P doping region, an intrinsic region and a high-concentration N doping region; and a controller that controls luminance of light emitted from the organic light emitting diode, to a constant level by controlling a voltage applied to the first electrode and the second electrode according to the voltage outputted from the photo diode. | 2014-03-27 |
20140087496 | METHODS AND STRUCTURES FOR FORMING AND PROTECTING THIN FILMS ON SUBSTRATES - A method for forming of a thin film on a substrate is disclosed. The method includes cleaning a process chamber by flowing a first gas having fluorine. The method also includes coating the process chamber with a first encapsulating layer including amorphous silicon (A-Si) by flowing a second gas for a first duration, where the first encapsulating layer protects against fluorine contamination. The method further includes loading a substrate into the process chamber, depositing a thin film on the substrate by flowing a third gas into the process chamber and unloading the substrate from the process chamber. The thin film can include silicon nitride (SiN), the first gas can include nitrogen triflouride (NF | 2014-03-27 |
20140087497 | BARRIER FILM FOR ELECTRONIC DEVICES AND SUBSTRATES - Methods for forming a coating over a surface are disclosed. A method includes directing a first source of barrier film material toward a substrate in a first direction at an angle θ relative to the substrate, wherein θ is greater than about 0° and less than about 85°. Additionally, a method of depositing a barrier film over a substrate includes directing a plurality of N sources of barrier film material toward a substrate, each source being directed at an angle θ | 2014-03-27 |
20140087498 | METHOD OF MANUFACTURING LIGHT-EMITTING DEVICE - A method of manufacturing a light-emitting device includes mounting an LED chip on a bottom surface of a recessed portion of a case, and after mounting the LED chip, forming a highly-reflective sidewall so as to be in contact with side surfaces and the bottom surface of the recessed portion and to be spaced from the LED chip. The highly-reflective sidewall includes a higher light reflectance than the side surfaces of the recessed position of the case and an outwardly convex surface as a surface exposed in the recessed portion. | 2014-03-27 |
20140087499 | METHOD FOR HANDLING A SEMICONDUCTOR WAFER ASSEMBLY - Systems and methods for fabricating a light emitting diode include forming a multilayer epitaxial structure above a carrier substrate; depositing at least one metal layer above the multilayer epitaxial structure; removing the carrier substrate. | 2014-03-27 |
20140087500 | TRANSPARENT CONDUCTIVE ELECTRODE STACK CONTAINING CARBON-CONTAINING MATERIAL - A transparent conductive electrode stack containing a work function adjusted carbon-containing material is provided. Specifically, the transparent conductive electrode stack includes a layer of a carbon-containing material and a layer of a work function modifying material. The presence of the work function modifying material in the transparent conductive electrode stack shifts the work function of the layer of carbon-containing material to a higher value for better hole injection into the OLED device as compared to a transparent conductive electrode that includes only a layer of carbon-containing material and no work function modifying material. | 2014-03-27 |
20140087501 | DOPED GRAPHENE TRANSPARENT CONDUCTIVE ELECTRODE - Graphene is used as a replacement for indium tin oxide as a transparent conductive electrode which can be used in an organic light emitting diode (OLED) device. Using graphene reduces the cost of manufacturing OLED devices and also makes the OLED device extremely flexible. The graphene is chemically doped so that the work function of the graphene is shifted to a higher value for better hole injection into the OLED device as compared to an OLED device containing an undoped layer of graphene. An interfacial layer comprising a conductive polymer and/or metal oxide can also be used to further reduce the remaining injection barrier. | 2014-03-27 |
20140087502 | LIGHT EMITTING DIODE CHIP HAVING DISTRIBUTED BRAGG REFLECTOR AND METHOD OF FABRICATING THE SAME - Exemplary embodiments of the present invention disclose a light emitting diode chip including a substrate having a first surface and a second surface, a light emitting structure arranged on the first surface of the substrate and including an active layer arranged between a first conductive-type semiconductor layer and a second conductive-type semiconductor layer, a distributed Bragg reflector arranged on the second surface of the substrate, the distributed Bragg reflector to reflect light emitted from the light emitting structure, and a metal layer arranged on the distributed Bragg reflector, wherein the distributed Bragg reflector has a reflectivity of at least 90% for light of a first wavelength in a blue wavelength range, light of a second wavelength in a green wavelength range, and light of a third wavelength in a red wavelength range. | 2014-03-27 |
20140087503 | Method for fabricating a display panel - A method for fabricating a display panel includes the following steps. A surface of a first substrate is adhered to a first supporting substrate with a first adhesive layer. First devices are formed on the other surface of the first substrate. The other surface of the first substrate is adhered to a second supporting substrate with a second adhesive layer. The first adhesive layer and supporting substrate are separated from the first substrate. Second devices are formed on the surface of the first substrate. A second substrate is adhered to a third supporting substrate with a third adhesive layer. The first substrate and the second substrate are assembled, and a display medium layer is interposed between the first substrate and the second substrate. The second adhesive layer and supporting substrate are separated from the first substrate, and the third adhesive layer and supporting substrate are separated from the second substrate. | 2014-03-27 |
20140087504 | OLED DISPLAY WITH SPALLED SEMICONDUCTOR DRIVING CIRCUITRY AND OTHER INTEGRATED FUNCTIONS - Spalling is employed to generate a single crystalline semiconductor layer. Complementary metal oxide semiconductor (CMOS) logic and memory devices are formed on a single crystalline semiconductor substrate prior to spalling. Organic light emitting diode (OLED) driving circuitry, solar cells, sensors, batteries and the like can be formed prior to, or after, spalling. The spalled single crystalline semiconductor layer can be transferred to a substrate. OLED displays can be formed into the spalled single crystalline semiconductor layer to achieve a structure including an OLED display with semiconductor driving circuitry and other functions integrated on the single crystalline semiconductor layer. | 2014-03-27 |
20140087505 | Light-Emitting Diodes on Concave Texture Substrate - A semiconductor device having light-emitting diodes (LEDs) formed on a concave textured substrate is provided. A substrate is patterned and etched to form recesses. A separation layer is formed along the bottom of the recesses. An LED structure is formed along the sidewalls and, optionally, along the surface of the substrate between adjacent recesses. In these embodiments, the surface area of the LED structure is increased as compared to a planar surface. In another embodiment, the LED structure is formed within the recesses such that the bottom contact layer is non-conformal to the topology of the recesses. In these embodiments, the recesses in a silicon substrate result in a cubic structure in the bottom contact layer, such as an n-GaN layer, which has a non-polar characteristic and exhibits higher external quantum efficiency. | 2014-03-27 |
20140087506 | ZINC OXIDE-CONTAINING TRANSPARENT CONDUCTIVE ELECTRODE - A transparent conductive electrode stack containing a work function adjusted zinc oxide is provided. Specifically, the transparent conductive electrode stack includes a layer of zinc oxide and a layer of a work function modifying material. The presence of the work function modifying material in the transparent conductive electrode stack shifts the work function of the layer of zinc oxide to a higher value for better hole injection into the OLED device as compared to a transparent conductive electrode that includes only a layer of zinc oxide and no work function modifying material. | 2014-03-27 |
20140087507 | Polythiophene-Containing Ink Compositions For Inkjet Printing - Ink compositions comprising polythiophenes and methicone that are formulated for inkjet printing the hole injecting layer (HIL) of an organic light emitting diode (OLED) are provided. Also provided are methods of inkjet printing the HILs using the ink compositions. | 2014-03-27 |
20140087508 | METHOD FOR PRODUCING GROUP III NITRIDE SEMICONDUCTOR LIGHT-EMITTING DEVICE - The present invention provides a method for producing a Group III nitride semiconductor light-emitting device wherein a p-cladding layer has a uniform Mg concentration. A p-cladding layer having a superlattice structure in which AlGaN and InGaN are alternately and repeatedly deposited is formed in two stages of the former process and the latter process where the supply amount of the Mg dopant gas is different. The supply amount of the Mg dopant gas in the latter process is half or less than that in the former process. The thickness of a first p-cladding layer formed in the former process is 60% or less than that of the p-cladding layer, and 160 Å or less. | 2014-03-27 |