12th week of 2013 patent applcation highlights part 48 |
Patent application number | Title | Published |
20130072333 | BICYCLE FRONT DERAILLEUR - A bicycle front derailleur is basically provided with a base member, a movable member and a biasing arrangement. The biasing arrangement is operatively disposed between the base member and the movable member such that a biasing force of the biasing arrangement is smaller during an early range of a movement range of the movable member as the movable member moves from a first position to a second position. The biasing arrangement includes a first biasing member, a second biasing member and a pre-load body. The first and second biasing members selectively bias the movable member. The pre-load body maintains the second biasing member in a loaded state such that the second biasing member applies the second biasing force only after the movable member has partially moved from the first position towards the second position. | 2013-03-21 |
20130072334 | Sprocket for Rear Wheel of a Bicycle - The present invention relates to a sprocket for use with a bicycle, the sprocket for use with a multi-sprocket assembly and chain, wherein the sprocket is made from a light but comparatively soft material and does not have shifting aids in the form of recesses and notches on the sprocket teeth where the chain rollers are in contact with the load flanks of the teeth. | 2013-03-21 |
20130072335 | TOOTHED BELT AND METHOD OF MANUFACTURING THE SAME - A toothed belt has therein a core wire ( | 2013-03-21 |
20130072336 | POWERTRAIN WITH TWO PLANETARY GEAR SETS AND TWO MOTOR/GENERATORS FOR HYBRID VEHICLE - A powertrain includes an input member, an output member, and a stationary member. A first and a second electric motor/generator are provided. Only two planetary gear sets are used, each having a respective first, second, and third member. An interconnecting member connects one of the members of a first one of the planetary gear sets to one of the members of a second one of the planetary gear sets. The input member, the output member, the first motor/generator and the second motor/generator are each continuously connected for common rotation with a different one of the members of the planetary gear sets that is not connected by the interconnecting member. Four brakes are each selectively engageable to ground a different respective one of the members of the planetary gear sets that is not connected by the interconnecting member to the stationary member. | 2013-03-21 |
20130072337 | HYBRID POWER TRAIN FOR VEHICLES - A hybrid power train for vehicles uses a double clutch transmission (DCT) to further improve the fuel efficiency of a vehicle, obtain a sporty transmission, and prevent the entire length thereof from being excessively lengthened, thereby sufficiently securing the ability of being mounted in a vehicle. | 2013-03-21 |
20130072338 | Hydrodynamic Clutch Device - A wet clutch arrangement includes a housing arrangement which is filled or fillable with fluid, a first friction surface formation which is rotatable with the housing arrangement around an axis of rotation and a second friction surface formation which is rotatable with a driven member around the axis of rotation and which can be brought into frictional engagement with the first friction surface formation by a piston pump. At least a portion of a torsional vibration damping arrangement is provided in a torque transmission path and includes an input region and an output region. The torsional vibration damping arrangement further includes at least in a first torque transmission path a phase shifter arrangement for generating a phase shift of rotational irregularities transmitted via the first torque transmission path relative to rotational irregularities transmitted via a second torque transmission path. | 2013-03-21 |
20130072339 | AUTOMATIC GEARBOX TRANSMISSION SYSTEM FOR ELECTROMECHANICAL HYBRID POWER VEHICLE - A drive train for an automatic transmission for an electromechanical hybrid vehicle is disclosed. The drive train is designed as a whole consisting of only 29 major parts and units, capable of generating 6 forward shifts and 1 reverse shift. A motor is wholly arranged on an input shaft such that the rotation speeds of the motor and the input shaft are synchronous. The motor has the functions of an electric generator and can drive a vehicle to run by a reactive force generated by the magnetic field of the electric generator such that the vehicle generates power during running and therefore avoids consuming the power of the engine due to the load of the electric generator, and thus, the aim of power conservation is achieved. In the hybrid drive mode, the vehicle does not need a clutch and a brake to shift the gear at the moment of startup and during running and therefore realizes stepless transmission and can transmit a large torque. | 2013-03-21 |
20130072340 | CONTINUOUSLY AND/OR INFINITELY VARIABLE TRANSMISSIONS AND METHODS THEREFOR - An infinitely variable transmission (IVT) having a rotatable input shaft arranged along a longitudinal axis of the transmission. In one embodiment, the input shaft is adapted to supply a lubricant to the interior of the transmission. In some embodiments, a stator assembly is coupled to, and coaxial with, the input shaft. The IVT has a plurality of planets operably coupled to the stator assembly. The planets are arranged angularly about the longitudinal axis of the transmission. In one embodiment, a traction ring is operably coupled to the planets. The WT is provided with a housing that is operably coupled to the traction ring. The housing is substantially fixed from rotating with the input shaft. The traction ring is substantially fixed from rotating with the input shaft. In some embodiments, the IVT is provided with a lubricant manifold that is configured to supply a lubricant to the input shaft. | 2013-03-21 |
20130072341 | MULTI-SPEED GEAR SYSTEM FOR POWER TOOL - A multi-speed gear system for a power tool includes a case, a lever, a gear disk, a movable member, a ring gear, a planet gear unit and an idle gear unit. The movable member is axially moved to be engaged with the ring gear, the planet gear unit or the idle gear unit to change the gear ratios and output different speeds. The parts that are engaged with the movable member are located outside of the area where the gears are located, so that the switching between the speeds is smooth and has less friction. | 2013-03-21 |
20130072342 | TRANSMISSION FOR VEHICLE - A transmission for a vehicle employs four planetary gear trains to realizing at least forward 10-speed and reverse 3-speed gear ratios, thereby reducing the number of rotations of a second sun gear of a second planetary gear train so as to increase the efficiency of power transmission and to improve the longevity of related components of the second planetary gear train, such as a pinion gear, a pinion shaft, and a needle roller bearing. | 2013-03-21 |
20130072343 | TRANSMISSION FOR VEHICLE - A transmission for a vehicle employs parts as few as possible to provide forward 11-speed and reverse 3-speed gear ratios along with relatively simple configuration, thereby allowing the operational state of an engine connected thereto to achieve an optimal state. Thus, the transmission makes it possible to improve fuel efficiency and to secure smooth driving performance of the vehicle. | 2013-03-21 |
20130072344 | MULTIPLE-ROW EPICYCLIC GEAR - A multiple-row epicyclic gear includes a carrier with planet gears arranged in rows, as well as a composite central ring gear, having major crowns, with friction spacer rings disposed there between, are also mounted in the housing. The elements of the central ring gear are axially spring loaded. The end faces of the frictional spacer rings and counter-oriented end faces of the major crowns have tapered surfaces being in frictional contact. The friction spacer rings are spliced and arranged to bring their outer cylindrical surfaces into frictional contact with the inner cylindrical surface of the housing. The planet gears are disposed on the carrier in rows in corresponding apertures (or through openings) formed in the carrier. The optimal cone apex angle (δ) of the contacting tapered end faces of the major crowns and tapered end faces of the friction spacer rings is in the range 60-90°. | 2013-03-21 |
20130072345 | PLANETARY GEAR UNIT - A planetary gear unit inside a case includes coaxial sun and ring gears, a planetary pinion gear that meshes with the sun and ring gears, and a carrier that holds the planetary pinion gear, the ring gear being fixed with respect to the case, and a flange disposed inward of the ring gear. The ring gear is fixed to a case wall, via the flange, the wall extending radially inward, and the flange being prevented from rotating with respect to the wall by a rotation prevention mechanism. The rotation prevention mechanism includes a plurality of case holes on the same circle in the wall, flange holes in the flange at positions corresponding to the case holes, and rotation prevention members fitted into the case and flange holes to prevent rotation of the flange with respect to the wall with the flange relatively movable axially with respect to the wall. | 2013-03-21 |
20130072346 | Torsional Vibration Damping Arrangement - A torsional vibration damping arrangement, particularly for a drivetrain with an automatic transmission, includes an input region and an output region, wherein a first torque transmission path and parallel thereto a second torque transmission path and a coupling arrangement for superposing the torques transmitted via the torque transmission paths are provided between the input region and the output region. The torsional vibration damping arrangement further includes at least in the first torque transmission path a phase shifter arrangement for generating a phase shift of rotational irregularities transmitted via the first torque transmission path relative to rotational irregularities transmitted via the second torque transmission path. | 2013-03-21 |
20130072347 | DRIVETRAIN FOR A PARALLEL HYBRID VEHICLE - A drivetrain ( | 2013-03-21 |
20130072348 | METHOD AND APPARATUS FOR ADAPTIVE CLUTCH CONTROL FOR A VEHICLE HAVING ENGINE START-STOP FUNCTIONALITY - A vehicle includes an engine, torque converter, transmission, accumulator, sensor, and controller. The engine is automatically restarted in response to a start signal during an engine auto-start event. The transmission has a calibrated line pressure and a plurality (n) of clutches. The (n) clutches are engaged to execute the engine auto-start event. The accumulator delivers fluid under pressure to the transmission in response to the start signal. The controller controls (n−1) of the plurality (n) of clutches to the calibrated line pressure in response to detecting the start signal. The controller also modifies clutch fill parameters which control a fill sequence of the remaining clutch, i.e., the designated control clutch, as a function of a deviation of the measured turbine speed from a theoretical no-slip turbine speed. A system includes the transmission, sensor, accumulator, and controller. A method for controlling the designated clutch is also disclosed. | 2013-03-21 |
20130072349 | AUTOMATIC SPEED CONTROL SYSTEM FOR MANUAL TRANSMISSION - Disclosed therein is an automatic speed control system for a manual transmission. Clutch operating means using a combination of a motor and gears, transmission lever operating means using a combination of a motor and gears, and a control part, which check a driving state of a vehicle in real time and controls the motor if gear-shifting is needed, are additionally mounted to a general manual transmission, so that the general manual transmission can automatically shift the gear like an automatic transmission. | 2013-03-21 |
20130072350 | VEHICLE SHIFT CONTROL DEVICE - It is provided a vehicle shift control device electrically switching a shift position between a parking position and a non-parking position, the vehicle being capable of switching a vehicle state among a first state, a second state and a third state, when an operation for switching the vehicle state is performed in the first state, if a vehicle speed is a predetermined speed or less, switching is executed to the parking position and, after completion of the switching, the vehicle state is switched to the third state, whereas when plural-times of the operations are performed successively during the vehicle running, the vehicle state is compulsorily switched to the second state, and when at least one operation of the plural-times of the operations is performed if the vehicle speed is the predetermined speed or less, switching to the parking position is executed prior to switching to the second state. | 2013-03-21 |
20130072351 | BRAKE MONITORING SYSTEM AND METHOD - A brake monitoring system and method for a vehicle having multiple axles and a plurality of brake actuators and an engine control module, each brake actuator being associated with one of the axle. The system include sensors for measuring, in real-time, brake pressure and brake lining wear, and generating first and second signals. The first and second signals are received and stored in a chassis communications module. The chassis communications module detects fault condition of the brakes as a function of the first and/or second signals and for recording the fault condition, the fault condition being one of a brake monitor warning and a brake lining warning and provides an indication of status via warning lights. | 2013-03-21 |
20130072352 | SPINE EXERCISE APPARATUS - Disclosed herein is a spine exercise apparatus which makes it possible for a user to actively perform spine exercise in a variety of postures. The spine exercise apparatus includes a base plate, a support unit, a plate drive unit and a control box. The base plate includes body contact units which come into contact with portions of the user's body and support the user's body. The support unit protrudes from the base plate and supports another portion of the user's body. The plate drive unit supplies power to the plate so that the plate moves in a plurality of degrees of freedom. The control box creates a plate drive signal containing information about the power to be supplied by the plate drive unit and provides the plate drive signal to the plate drive unit. | 2013-03-21 |
20130072353 | APPARATUS FOR THE ASSISTED PERFORMANCE OF A FITNESS EXERCISE - An apparatus ( | 2013-03-21 |
20130072354 | Athletic Agility Equipment and Methods of Using the Same - The present invention relates to a grid apparatus that is useful for the training of athletes in speed, agility, strength, plyometrics, balance, cardiovascular and other training exercise activities. The grid apparatus allows athletes to move forward, backward, side to side, and diagonal at multiple height settings. Specifically, the present invention relates to a grid apparatus that has the ability to be held tight and maintain its shape while on any athletic surface. More specifically, the present invention relates to a grid apparatus that may be suspended above the ground at specific heights. The grid apparatus includes, generally, one or more straps intersecting in a grid configuration and one or more stabilizers to functionally suspend the grid apparatus above the ground. | 2013-03-21 |
20130072355 | Collapsible Athletic Training Ladder - A collapsible ladder for use primarily for athletic training and the like has a plurality of spaced-apart, substantially rigid rungs secured with collapsible connectors to a plurality of spaced-apart, substantially rigid spacers extending therebetween. In one disclosed embodiment, the collapsible connectors are strips of flexible material extending between the rungs and spacers. Another disclosed embodiment has a second set of rungs aligned substantially parallel to the plurality of spaced-apart rungs along a common central set of spacers. The collapsible connectors allow the ladder to be quickly and easily transitioned between an extended, operational position, and a collapsed, storage position. | 2013-03-21 |
20130072356 | STATIONARY EXERCISE BICYCLE - A stationary exercise bicycle includes a base, and right and left pedals mounted to the base. The pedals are configured to rotate in operation about an axis of rotation. A frame has a rear end pivotally mounted to the base, and a forward end spaced apart from the rear end. A saddle is coupled to the rear end of the frame, and a handlebar is coupled to the forward end of the frame. The stationary exercise bicycle includes an actuator coupling the frame to the base. The actuator is configured to pivot the frame relative to the base about the axis of rotation, which can enable the rider to maintain the same general position as the frame is pivoted between normal and inclined positions. | 2013-03-21 |
20130072357 | Core XT trainer bag - The design of a center weight lift bar, internal weights and strategically placed hand grips satisfies the different requirements for health and martial arts training that are presently not met by existing conventional training bags. The redesigned Core XT Trainer Bag is not only designed for a variety of exercises, the bag also employs the maximum in safety technology to avoid contact injury to the users. The extensive versatility of this trainer bag makes it a highly usable training tool due to it's replacement of multiple single function bags. | 2013-03-21 |
20130072358 | Target Simulating Heavy Bag Cover - A target simulating heavy bag cover comprises a sheet, a simulation image, and a fastener. The sheet wraps around the heavy bag and braces the target simulating heavy bag cover against the heavy bag. The sheet provides additionally cushioning between the user's physical attacks and the heavy bag so that the heavy bag does not deform and the physical damage to the user's body is reduced. The simulation image is printed onto the sheet and provides the user with a number of realistic targets on the human body. The simulation image allows the user to hone the accuracy of their physical attacks aiming for the targets. The fastener is used to attach one end of the sheet to the other end of the sheet once the sheet is wrapped around the heavy bag. | 2013-03-21 |
20130072359 | SPRING COLLARS AND SPRING COLLAR ATTACHMENTS HAVING PERMANENT MAGNETS AND ASSOCIATED METHODS - Embodiments of a spring collar are provided for removably securing a disc weight to the sleeve of a barbell, as are embodiments of a magnetic spring collar attachment and associated methods. In one embodiment, the spring collar includes a resilient wire form having a permanent magnet mounted thereto. The spring collar includes a coiled body having a central aperture, and first and second radial arms extending from the coiled body. The first and second radial arms can be moved toward one another to increase the diameter of the central aperture and permit a user to slide the coiled body over the sleeve. The permanent magnet enables a user to removably secure the spring collar to a ferromagnetic surface when the spring collar is not in use. | 2013-03-21 |
20130072360 | BACK-EXTENSION CHAIR FOR THE PREVENTION OF LOW BACK PAIN SYMPTOMS - A chair-like exercising apparatus comprises a back, a seat, front legs, rear legs, and resistance element(s) which provide a broad range of resistance force adjustable by the user for the back extension exercise. The chair back pivotally connects to the rear legs directly, and pivotally connects to the front legs or rear legs through the resistance element(s). The resistance element comprises a compress-coil-spring cylinders (or constant-force-spring devices) and the cylinder holders (or the device holders). The resistance level of the back extension exercise is adjusted by switching the interchangeable compress-coil-spring cylinders (or constant-force-spring devices) of appropriate loads inside the cylinder holders (or device holders). A user sits on the chair and sway backward to perform back extension exercise after selecting an appropriate resistance level based on his/her physical condition. The apparatus is simple, affordable and can be used as a regular chair in its locked position. A regular back extension exercise with proper resistance force strengthens the low back muscles (erector spinae), improves and prevents the low back pain symptoms. | 2013-03-21 |
20130072361 | Exercise Apparatus - A complex exercise machine utilizes a horizontally extending frame assembly having a plurality of resistance elements. A plurality of foot pedals are included that are slidably mounted on the frame assembly. The foot pedals are moveable between a first position, proximate to the user, and a second distal position. The resistance elements have a first end and a second end. The first end of the resistance element is removably anchored to the frame assembly A first resistance element includes a handle at its second to exercise upper body muscle groups, while a second resistance element includes the pedals at its second end to exercise lower body and abdominal muscle groups. A seat is provided that is adjustably mounted to the frame assembly. The angulation between the seat back and seat bottom is also adjustable. | 2013-03-21 |
20130072362 | BACK STRETCHING MACHINE - An apparatus for stretching the lower back. A person lie supine on a horizontal padded surface at the end of which are two vertical rigid foot bars. The person wears a waist band around his waist and connects the waist band to left and right elastic members, each of which is connected to a respective foot bar. By pushing his feet against the foot bars, the person pushes the remainder of his body away from the foot bars, thereby stretching the elastic members and imposing a therapeutic force on his lower back. | 2013-03-21 |
20130072363 | BACK STRETCHING MACHINE - An apparatus for stretching the lower back. A person lie supine on a horizontal padded surface at the end of which are two vertical rigid foot bars. The person wears a waist band around his waist and connects the waist band to left and right elastic members, each of which is connected to a respective foot bar. By pushing his feet against the foot bars, the person pushes the remainder of his body away from the foot bars, thereby stretching the elastic members and imposing a therapeutic force on his lower back. | 2013-03-21 |
20130072364 | PUSH-UP EXERCISER - A push-up exerciser has a base, two handgrips, a connecting rod having two ends respectively connected pivotally to the base and a supporter, at least one resilient element connected to the connecting rod and the supporter, a roller pivotally mounted on a lower end of the supporter, and a pad pivotally mounted on an upper end of the supporter. A user places his/her abdomen on the pad, grasps the handgrips and then bends or straightens his/her arms to perform push-ups. Since the at least one resilient element tends to pull the supporter and the connecting rod so the pad tends to support the abdomen of the user, load applied to the arms of the user is reduced. The push-up exerciser has simplified structure, low manufacturing cost and helps the user to safely perform push-ups. | 2013-03-21 |
20130072365 | PUSH-PULL HANDLES - An exercise device for performing push ups and pull ups is disclosed. The device contains first and second tubes slidably engaged with a handle, which may be covered by a grip. A spring biases to the two tubes, drawing them inwardly together with respect to the handle. A first foot tube, including a first base, engages the second end of the first tube; a first button connector arranged to selectively lock the first foot tube with respect to the second end of the first tube. A second foot tube, including a second base, engages the second end of the second tube; and a second button connector selectively locks the second foot tube with respect to the second end of the second tube. The device may be engaged with a door frame to perform pull-ups. | 2013-03-21 |
20130072366 | COIL-TUBE CHUNK FOR A ROLL FEEDER - A coil-tube chunk for a roll feeder has at least one colleting device. Each of the at least one colleting device has a base and a chunk. The base has a mounting stand, a sharp-tooth mount and multiple screwing rods. The mounting stand is formed on and protrudes from the base. The sharp-tooth mount is formed on the base around the mounting stand. The screwing rods are respectively and securely mounted on the sharp-tooth mount. The chunk is mounted securely on the base and has a guiding face, multiple grooves and multiple engaging teeth. The guiding face is aslantly formed on an external surface of the chunk. The grooves are formed in the external surface and the guiding frace of the chunk at intervals. The engaging teeth are formed on the external surface and the guiding face of the chunk between the grooves. | 2013-03-21 |
20130072367 | Blood Processing Apparatus with Robust Automated Process Control - A centrifuge for separating blood having a camera observing fluid flow, and a controller controlling the flow. The location of an interface is detected by image processing steps, which may comprise the steps of “spoiling” the image, “diffusing” the image, “edge detection”, “edge linking”, “region-based confirmation”, and “interface calculation”. “Spoiling” reduces the number of pixels to be examined preferentially on orthogonal axis oriented with respect to the expected location of the interface or phase boundary. “Diffusing” smoothes out small oscillations in the interface boundary, making to the location of the interface more distinct. “Edge detection” computes the rate of change in pixel intensity. “Edge linking” connects adjacent maxima. “Region-based confirmation” creates a pseudo image of the regions that qualify as distinct. “Final edge calculation” uses the points where the shade changes in the pseudo image, averages the radial displacement of these points for the interface position. | 2013-03-21 |
20130072368 | CASSETTE AND SYSTEM COMPONENT INSERTABLE INTO A CENTRIFUGE IN COOPERATION WITH THE CASSETTE - The invention pertains to a cassette ( | 2013-03-21 |
20130072369 | CENTRIFUGAL SEPARATOR - A centrifugal separator includes a separation drum, a feed inlet, at least one heavy material outlet with a ring-shaped recess and at least one light material outlet. The feed inlet is located at the head of the separation drum. A feed accelerator is installed at the feed inlet. This feed accelerator cooperates with the proper form of the separation drum and the corresponding location of the material outlet to form a material differential rotation propulsion device. The material differential rotation propulsion device is capable of rotating the feed slurry material along with the separation drum in a slightly different rotation speed and forcing the processed materials to be discharged from separation drum via different outlets. The infeed flow rate is larger than or equal to the total sum of the outfeed flow rates of heavy and light materials so that the separation drum is full of materials during operation. | 2013-03-21 |
20130072370 | Methods for Reducing Defects in Ceramic Articles and Precursors - A method of reducing the defects in ceramic articles and precursors, particularly ceramic articles and precursors made using a batch composition containing an oil phase material. The method includes increasing the concentration of a water insoluble soap in the batch composition, which can increase the cohesive strength of the oil phase, leading to a reduction in the incidence of defects in the ceramic articles and precursors. | 2013-03-21 |
20130072371 | METHOD OF, AND APPARATUS FOR, USING A GLASS FLUXING AGENT TO REDUCE FOAM DURING MELTING OF GLASS BATCH - A foam and frothy glass mixture that forms on a pool of molten glass and inhibits heat transfer between the overhead flames and the pool of molten glass is decreased, if not eliminated, by spreading a glass fluxing agent, e.g. but not limiting to the invention, sodium sulfate over the foam and/or frothy glass mixture. | 2013-03-21 |
20130072372 | OPTICAL GLASS - There is provided an optical glass with a high refractive index and a low dispersion having a refractive index (nd) of not less than 1.75 and an Abbe's number (νd) of not less than 35 where the image formation characteristic is hardly affected by changes in temperature of the using environment. SiO | 2013-03-21 |
20130072373 | ALUMINA-BASED OPAQUE CERAMIC - The invention relates to an alumina-based opaque ceramic, similar to ruby and having a high toughness. This ceramic comprises, by weight: 0.4% to 5% of at least from one oxide of a metal chosen from chromium, cobalt, nickel, manganese, vanadium, titanium and iron; 0.00080 to 0.5% of magnesium oxide; and 0.05 to 6% of at least one oxide of an element of the group of rare earths. The ceramic is applicable in particular in jewellery, fine jewellery and watch making. The invention also relates to methods of preparing such a ceramic. | 2013-03-21 |
20130072374 | CATALYST CONTAINING OXYGEN TRANSPORT MEMBRANE - A composite oxygen transport membrane having a dense layer, a porous support layer and an intermediate porous layer located between the dense layer and the porous support layer. Both the dense layer and the intermediate porous layer are formed from an ionic conductive material to conduct oxygen ions and an electrically conductive material to conduct electrons. The porous support layer has a high permeability, high porosity, and a microstructure exhibiting substantially uniform pore size distribution as a result of using PMMA pore forming materials or a bi-modal particle size distribution of the porous support layer materials. Catalyst particles selected to promote oxidation of a combustible substance are located in the intermediate porous layer and in the porous support adjacent to the intermediate porous layer. The catalyst particles can be formed by wicking a solution of catalyst precursors through the porous support toward the intermediate porous layer. | 2013-03-21 |
20130072375 | CATALYST CONTAINING OXYGEN TRANSPORT MEMBRANE - A composite oxygen transport membrane having a dense layer, a porous support layer and an intermediate porous layer located between the dense layer and the porous support layer. Both the dense layer and the intermediate porous layer are formed from an ionic conductive material to conduct oxygen ions and an electrically conductive material to conduct electrons. The porous support layer has a high permeability, high porosity, and a microstructure exhibiting substantially uniform pore size distribution as a result of using PMMA pore forming materials or a bi-modal particle size distribution of the porous support layer materials. Catalyst particles selected to promote oxidation of a combustible substance are located in the intermediate porous layer and in the porous support adjacent to the intermediate porous layer. The catalyst particles can be formed by wicking a solution of catalyst precursors through the porous support toward the intermediate porous layer. | 2013-03-21 |
20130072376 | NOVEL CATALYST REGENERATION ZONE DIVIDED INTO SECTORS FOR REGENERATIVE CATALYTIC UNITS - The present invention describes a combustion zone for a regenerative catalytic unit for the continuous regeneration of catalyst, said combustion zone having an annular shape and being divided into at least two combustion stages, each stage being divided into a number N of radial sectors, which are substantially equal, the catalyst flowing under gravity from one sector of the first combustion stage to the sector located in vertical alignment with the second combustion stage by means of drop legs, and the movement of the combustion gas being such that the combustion gas passes in succession through all of the sectors of the first combustion stage in any order, then all of the sectors of the second stage in any order. | 2013-03-21 |
20130072377 | MULTIFUNCTIONAL CHAIN SHUTTLING AGENTS - The invention generally relates to chain shuttling agents (CSAs), a process of preparing the CSAs, a composition comprising a CSA and a catalyst, a process of preparing the composition, a processes of preparing polyolefins, end functional polyolefins, and telechelic polyolefins with the composition, and the polyolefins, end functional polyolefins, and telechelic polyolefins prepared by the processes. | 2013-03-21 |
20130072378 | NOVEL METHOD TO INCREASE VOLUMETRIC HYDROGEN STORAGE CAPACITY FOR PT/AC MATERIALS - A novel method to increase volumetric hydrogen storage capacity for Pt/AC materials, which comprising a providing material step, an acid washing step, a glucose mixing step, a pellet pressing step combining liquefaction and carbonization, a removing impurity step, a introducing mixed solution step, and a washing and filtering step to provide a method for high quality hydrogen storage material production by supporting platinum on active carbon. | 2013-03-21 |
20130072379 | METHOD OF MANUFACTURING CATALYST COATING SOLUTION AND CATALYST BODY USING THE SAME - A method of preparing a catalyst coating solution may realize high purification performance by preventing the active surface of a catalyst from being reduced, and may greatly improve the durability of a catalyst by preventing soot from directly coming into contact with a catalyst layer containing a precious metal so that the catalyst layer can continuously exhibit proper purification performance. A method of manufacturing a catalyst body using the catalyst coating solution, and a catalyst body manufactured by the method are also described. | 2013-03-21 |
20130072380 | INDUSTRIAL ABSORBENTS AND METHODS OF MANUFACTURING THE SAME - An industrial absorbent and methods of manufacturing the same. In one embodiment, the industrial absorbent includes a first scrim made from at least one thermoplastic material; a second scrim made from at least one thermoplastic material; and a middle layer positioned between the first and second scrims. The middle layer includes a dry-laid web of fire-retardant treated cellulose and opened, individuated staple bicomponent fiber. At least some of the bicomponent fiber in the middle layer is thermally bonded to at least some of the cellulose in the middle layer, and the first and second scrims are thermally bonded to the middle layer. | 2013-03-21 |
20130072381 | LOW SOLUBLE SOLIDS ACID GELS AND METHODS FOR MAKING SAME - A gel composition including a low ester pectin in an amount from about 1.0 to about 2.5 percent by weight of the gel composition, acetic acid in an amount such that the gel composition has a pH from about 2.4 to about 3.5, and having a gel strength from about 5 grains to about 250 grams. A method for making the gel is also disclosed. The method includes dissolving a low ester pectin in an acetic acid solution, heating the mixture to a temperature from about 80° C. to about 100° C., and cooling the mixture. | 2013-03-21 |
20130072382 | PESTICIDAL COMPOSITIONS - This document discloses molecules having the following formula (“Formula I”): | 2013-03-21 |
20130072383 | METHOD FOR ANTI-SPROUTING AND POSSIBLY FUNGICIDAL TREATMENT OF BULBS AND/OR TUBERS USING CLOVE OIL AND MINT OIL - The invention concerns a method for anti-sprouting and possible fungicidal treatment of bulbs and/or tubers comprising simultaneous, separate or time-staggered applications to the said bulbs and/or tubers of:
| 2013-03-21 |
20130072384 | Pesticidal Mixtures - The present invention relates to a mixture comprising [(3S,4R,4aR,6S,12R,12aS,12bS)-3-(cyclopropanecarbonyloxy)-6,12-dihydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-11H,12H-benzo[f]pyrano[4,3-b]chromen-4-yl]methyl cyclopropanecarboxylate and a fungicidal compound II in synergistic effective amounts, to the use of this mixture for controlling pests and for improving the plant health and to plant propagation material comprising this mixture. | 2013-03-21 |
20130072385 | METHODS FOR DELAYING BUD BREAK BY APPLYING ABA ANALOGS - The present invention is directed to methods for delaying bud break of perennial plants by applying abscisic acid (“ABA”) analogs to the plants before cold temperature induced dormancy in order to delay the timing of bud break in response to future temperature increases. | 2013-03-21 |
20130072386 | PHYSICAL MAP CONSTRUCTION OF WHOLE GENOME AND POOLED CLONE MAPPING IN NANOCHANNEL ARRAY - Methods for generating physical maps for polynucleotides, such as genomic DNA, are disclosed herein. Also disclosed are methods for identifying the source of polynucleotides. The methods can, for example, be used in physical map construction of whole genome. In addition, methods and systems capable of performing high throughput characterization of macromolecules using nanofludic devices are enclosed. | 2013-03-21 |
20130072387 | Method of Pooling and/or Concentrating Biological Specimens for Analysis - The present invention provides methods for concentrating and pooling liquid suspensions of biological specimens containing analytes of interest in a dry state. The dried biological specimens containing analytes of interest are reconstituted and released from the matrix for subsequent analysis in concentrated form. | 2013-03-21 |
20130072388 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN IN DNA SEQUENCING - Provided are novel nucleotides, nucleoside, and their derivatives described herein, that can be used in DNA sequencing technology and other types of DNA analysis. In one embodiment, the nucleotide or nucleoside with an unprotected 3′-OH group is derivatized at the nucleobase to include a fluorescent dye attached via a linker to a photocleavable terminating group. The photocleavable-fluorescent group is designed to terminate DNA synthesis as well as be cleaved so that DNA oligomers can be sequenced efficiently in a parallel format. The design of such rapidly cleavable fluorescent groups on nucleotides and nucleosides can enhance the speed and accuracy of sequencing of large oligomers of DNA in parallel, to allow rapid whole genome sequencing, and the identification of polymorphisms and other valuable genetic information, as well as allowing further manipulation and analysis of nucleic acid molecules in their native state following cleavage of the fluorescent group. | 2013-03-21 |
20130072389 | THERANOSTIC AND DIAGNOSTIC METHODS USING SPARC AND HSP90 - Provided herein are methods and systems of molecular profiling of diseases, such as cancer. The molecular profiling can be used to provide a diagnosis, prognosis, or theranosis for the disease, such as identifying a candidate treatment. The methods can detect overexpression of SPARC and HSP90. The cancer can be, e.g., a renal cell carcinoma or an interdigitating dendritic cell sarcoma. | 2013-03-21 |
20130072390 | Methods for Synthesizing Pools of Probes - Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays. | 2013-03-21 |
20130072391 | COMPOSITION, KIT, AND METHOD FOR DIAGNOSING ADHD RISK - The following disclosure relates to a technology of genotyping a particular single nucleotide polymorphism (SNP) having significant association with attention deficit hyperactivity disorder (ADHD) and using the SNP genotypes for predicting the risk of ADHD. The present invention relates to providing a method of predicting ADHD risk by identifying the nucleotide of rs5508181 SNP in GIT1, which is C or T at the 24926101st residue on human chromosome 17, and a linkage disequilibrium block harboring rs5508181. Further, the present invention relates to a composition for diagnosing ADHD risk, including a probe for detecting the SNP or a primer for amplifying the chromosomal region, and a diagnosing kit having the probe immobilized on a surface thereof. Therefore, the method, the composition and the kit for diagnosing ADHD risk according to the following disclosure are useful technologies that can conveniently classify risk groups for ADHD at high sensitivity. | 2013-03-21 |
20130072392 | Compositions, Kits, and Methods for Identification, Assessment, Prevention, and Therapy of Cancer - The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating human cancer. A variety of chromosomal regions (MCRs) and markers corresponding thereto, are provided, wherein alterations in the copy number of one or more of the MCRs and/or alterations in the amount, structure, and/or activity of one or more of the markers is correlated with the presence of cancer. | 2013-03-21 |
20130072393 | PANCREATIC CANCER MARKERS, AND DETECTING METHODS, KITS, BIOCHIPS THEREOF - The present invention provides microRNAs for assessing the status of pancreatic cancer in a subject, and provides methods, kits, and biochips for detecting said microRNAs. | 2013-03-21 |
20130072394 | KETOL-ACID REDUCTOISOMERASE USING NADH - Methods for the evolution of NADPH binding ketol-acid reductoisomerase enzymes to acquire NADH binding functionality are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from | 2013-03-21 |
20130072395 | METHOD FOR EARLY DETECTION OF CANCERS - The invention includes methods for detecting the presence of a neoplastic condition by comparing a sample level of a BIF-1 to a reference, wherein a low level of BIF-1 in the sample correlates with the presence of a neoplastic condition. Another method involves determining the risk of relapse, tumor recurrence and/or metastasis by determining a sample level of a Bif-1 to a reference level of Bif-1, wherein low sample levels correlate with a likelihood of relapse, recurrence and/or metastasis. Yet another method includes detecting the presence of a pre-neoplastic condition, such as prostatic intraepithelial neoplasia. The method involves measuring a level of a Bif-1 in a sample and comparing the level of Bif-1 in the sample to a reference level of Bif-1. High levels of Bif-1 in the sample correlate with the presence of the pre-neoplastic condition. | 2013-03-21 |
20130072396 | Transplant Rejection Markers - The invention relates to the analysis and identification of genes that are regulated simultaneously in chronic kidney transplant rejection. This simultaneous regulation of genes provides a molecular signature to accurately detect, and optionally classify, chronic kidney transplant rejection. | 2013-03-21 |
20130072397 | METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF A TUMOR USING BCAT1 PROTEIN - The present invention relates to methods for the diagnosis of a tumor, in particular a brain tumor, and for the estimation of a prognosis for patients afflicted with such tumor based on the determination of expression of BCAT1 in a patient sample. | 2013-03-21 |
20130072398 | Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis - Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen | 2013-03-21 |
20130072399 | METHOD AND KIT FOR DISCRIMINATING BETWEEN BREAST CANCER AND BENIGN BREAST DISEASE - A method and kit are related to discriminating between breast cancer and benign breast disease by the determination of the expression level of at least one target gene including a nucleic acid sequence selected from the nucleic acid sequences set forth in SEQ ID NOs: 1, 2 or 3, 4 and 5 or 6 to obtain an expression profile for the patient, and the comparison of the expression profile of the patient with expression profiles of target genes from patients previously clinically classified as breast cancer and expression profiles of target genes from patients previously clinically classified as benign breast disease. | 2013-03-21 |
20130072400 | METHOD FOR THE DIAGNOSIS/PROGNOSIS OF COLORECTAL CANCER - The present invention relates to a method for obtaining useful data for the diagnosis, prognosis or monitoring of colorectal cancer (CRC) progression, to a method for the diagnosis of CRC, to a method for the prognosis of CRC and to a kit for carrying out said methods. | 2013-03-21 |
20130072401 | METHOD AND KIT FOR THE PROGNOSIS OF COLORECTAL CANCER - A method and kit for the prognosis of colorectal cancer where the method includes the steps of: a) obtaining a peripheral blood sample and extracting total RNA from the sample, b) contacting the total RNA with at least one reagent specific for at least one NK cell gene and no more than 25 specific reagents for 25 NK cell genes, c) determining the expression level of at least one and at most 25 NK cell genes to obtain an expression profile for the patient, d) analyzing the expression profile with expression profiles previously clinically classified as a good prognosis and as a poor prognosis, wherein if the expression profile is clustered with the poor prognosis profiles, then the patient is determined to have a poor prognosis, and if the expression profile is clustered with the good prognosis profiles, then the patient is determined to have a good prognosis. | 2013-03-21 |
20130072402 | METHOD FOR COLLECTING NUCLEATED RED BLOOD CELLS VIA DENSITY-GRADIENT CENTRIFUGATION UTILIZING CHANGES IN BLOOD CELL DENSITY - This invention provides a method for concentrating and collecting small quantities of fetal nucleated red blood cells contained in the maternal blood. The method for concentrating and collecting nucleated red blood cells from the maternal blood comprises: (i) subjecting the maternal blood to a first density-gradient centrifugation and collecting a cell fraction containing nucleated red blood cells; (ii) treating the cell fraction containing nucleated red blood cells so as to selectively changes the density of the nucleated red blood cells from that of the white blood cells; and (iii) subjecting the treated cell fraction containing the nucleated red blood cells to a second density-gradient centrifugation so as to collect a fraction containing nucleated red blood cells. | 2013-03-21 |
20130072404 | APPARATUS AND PROCESSES FOR GENERATING VARIABLE CONCENTRATION OF SOLUTES IN MICRODROPLETS - The present invention relates to systems and methods for generating microdroplets with varying concentrations of a particular solute from a solution at fixed concentration. | 2013-03-21 |
20130072405 | WATER-SOLUBLE POLYMERS FOR OIL RECOVERY - The present invention refers to the use of anionic water-soluble polymers being partially or totally neutralized with an organic counter-ion for oil filed application, especially tertiary oil recovery steps. | 2013-03-21 |
20130072406 | FILLER PARTICLES, RESIN COMPOSITION, GREASE, AND COATING COMPOSITION - The object of the present disclosure is to obtain a filler particle having stable insulation property, and a resin composition, grease and a coating composition comprising the same, respectively. | 2013-03-21 |
20130072407 | PREPARATION AND USE OF AMINOALKYLPHOSPHONIC ACID DILAKYL ESTER COMPOUNDS IN A LUBRICANT FOR ANTIWEAR, FRICTION REDUCTION, AND/OR MICROPITTING PREVENTION - In accordance with the disclosure, one aspect of the present application is directed to a lubricant additive composition. The lubricant additive composition includes a component or mixture of components selected from (a) an aminoalkylphosphonic acid dialkyl ester; (b) a cyclized product of an aminoalkylphosphonic acid dialkyl ester; and a mixture of (a) and (b). Preparation and use of the additive composition in a lubricant for antiwear and/or friction reduction are also disclosed. | 2013-03-21 |
20130072408 | USES AND COMPOSITIONS - The use of an oil-soluble mono-, di-, or tri-glyceride of at least one hydroxy polycarboxylic acid, or a derivative thereof, as an anti-wear additive and/or friction modifier in a non-aqueous lubricant composition and/or in a fuel composition. Also, a non-aqueous lubricant composition and a fuel composition for an internal combustion engine which comprise at least one additive which is an oil-soluble mono-, di-, or tri-glyceride of at least one hydroxy polycarboxylic acid, or a derivative thereof. | 2013-03-21 |
20130072409 | SOLVENT COMPOSITION FOR REMOVING RADIOACTIVE SUBSTANCE AND REMOVING MATERIAL, AND METHOD FOR REMOVING RADIOACTIVE SUBSTANCE - The present invention relates to a solvent composition for removing radioactive substance, characterized by comprising at least one selected from hydrofluorocarbon, hydrofluoroether, and perfluoroketone as a medium for transporting the radioactive substance, and a method for removing a radioactive substance characterized by using the solvent composition for removing. | 2013-03-21 |
20130072410 | Cleaning Formulations with Improved Surfactant Solubility and Methods of Production and Use Thereof - The present invention provides liquid cleaning compositions useful in cold water and hard water laundry applications, and methods for making and using such compositions. The compositions of the invention use surfactants or surfactant blends, such as α-sulfofatty acid esters or mixtures thereof (optionally along with one or more additional components), that have increased solubility/stability at cold temperatures, at higher-than-usual concentrations, and/or in hard water, with the composition remaining as a clear liquid. In certain embodiments, the compositions of the invention may be provided in the form of a unit dose, for example in a water-soluble pack or pouch. In use, the compositions of the invention result in an enhanced detergency along with a reduced amount of residue remaining in the machine, on laundered garments or cleaned dishware or hard surfaces, and on the body in personal care settings, and demonstrate a longer shelf-life, particularly when stored or used in colder temperatures. | 2013-03-21 |
20130072411 | AQUEOUS CLEANING COMPOSITION CONTAINING COPPER-SPECIFIC CORROSION INHIBITOR FOR CLEANING INORGANIC RESIDUES ON SEMICONDUCTOR SUBSTRATE - A semiconductor wafer cleaning formulation, including 1-35% wt. fluoride source, 20-60% wt. organic amine(s), 0.1-40% wt. nitrogenous component, e.g., a nitrogen-containing carboxylic acid or an imine, 20-50% wt. water, and 0-21% wt. metal chelating agent(s). The formulations are useful to remove residue from wafers following a resist plasma ashing step, such as inorganic residue from semiconductor wafers containing delicate copper interconnecting structures. | 2013-03-21 |
20130072412 | Detergent Composition - The present invention provides easy to handle, stable bleach material particle comprising a co-granulate of a bleach material, a water soluble binder and a disintegrant. It also provides easy to handle, stable shaped bodies comprising bleach material, a binder and a disintegrant where at least the bleach material and the binder are preferably co-granulated together. Detergent compositions comprising the bleach material particle or the shaped body are also provided. The products of the invention exhibit good solubility characteristics and bleachable stain removal performance. | 2013-03-21 |
20130072413 | DETERGENT COMPOSITIONS COMPRISING PRIMARY SURFACTANT SYSTEMS COMPRISING HIGHLY BRANCHED ISOPRENOID-BASED and OTHER SURFACTANTS - The present invention relates to detergent compositions containing a surfactant system comprising a highly branched surfactant as the primary surfactant. Specifically, the invention relates to detergent compositions containing a surfactant system comprising greater than about 25% of a highly branched surfactant. | 2013-03-21 |
20130072414 | DETERGENT COMPOSITIONS COMPRISING SUSTAINABLE SURFACTANT SYSTEMS COMPRISING ISOPRENOID-DERIVED SURFACTANTS - The present invention relates to detergent compositions containing a surfactant system comprising “sustainable” or bio-derived surfactant hydrophobes or “sustainable” or bio-derived surfactants. Specifically, the invention relates to detergent compositions containing a surfactant system that has a “Surfactant Hydrophobe Sustainability Index” (SHSI) greater than or equal to 0.70 or a “Surfactant Sustainability Index” (SSI) greater than or equal to 0.70. | 2013-03-21 |
20130072415 | DETERGENT COMPOSITIONS COMPRISING SPECIFIC BLEND RATIOS of ISOPRENOID-BASED SURFACTANTS - The present invention relates to detergent compositions containing a blend of selected isoprenoid-based surfactants and methods of making and using the same. | 2013-03-21 |
20130072416 | HIGH SUDS DETERGENT COMPOSITIONS COMPRISING ISOPRENOID-BASED SURFACTANTS - The present invention relates to detergent compositions containing a specific blend of isoprenoid-based surfactants to deliver high suds cleaning performance. | 2013-03-21 |
20130072417 | LIQUID DETERGENT COMPOSITION WITH ABRASIVE PARTICLES - A dishwashing composition comprising at least one surfactant, and natural abrasive particles wherein said natural abrasive particles comprise pistachio nut shell particles, a method of washing dishes with such compositions, and the use thereof. | 2013-03-21 |
20130072418 | METHOD FOR TREATING SCALES - Provided is a method for treating scales ( | 2013-03-21 |
20130072419 | CLEANING COMPOSITION WITH SURFACE MODIFICATION POLYMER - A cleaning composition includes water, glycerine, at least one alkyl polyglycoside and a surface modification polymer. The surface modification polymer acts to provides for initial cleaning or pretreatment of the hard surface and provides a hydrophilic coating or barrier layer on the surface which provides residual cleaning to the hard surface for an extended number of cleanings. The composition has an alkaline pH of from about 8 to 10. | 2013-03-21 |
20130072420 | BIOSYNTHETIC PROLINE/ALANINE RANDOM COIL POLYPEPTIDES AND THEIR USES - The present invention relates to a biosynthetic random coil polypeptide or a biosynthetic random coil polypeptide segment or biosynthetic conjugate, wherein said biosynthetic random coil polypeptide, said biosynthetic random coil polypeptide segment or said biosynthetic conjugate comprises an amino acid sequence consisting solely of proline and alanine amino acid residues, wherein said amino acid sequence consists of at least about 50 proline (Pro) and alanine (Ala) amino acid residues. Said at least about 50 proline (Pro) and alanine (Ala) amino acid residues may be (a) constituent(s) of a heterologous polypeptide or an heterologous polypeptide construct. Also uses and methods of use of these biosynthetic random coil polypeptides or polypeptide segments or said conjugates are described. | 2013-03-21 |
20130072421 | TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT) - The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s. | 2013-03-21 |
20130072422 | COMPOUNDS FOR IMMUNOPROTEASOME INHIBITION - One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention. | 2013-03-21 |
20130072423 | CD44V6 PEPTIDES AS INHIBITORS OF BACTERIAL INFECTIONS - The present invention relates to the use of peptide compounds for the prevention and/or treatment of a bacterial infection. | 2013-03-21 |
20130072424 | COMPOUNDS AND METHODS FOR PEPTIDE RIBONUCLEIC ACID CONDENSATE PARTICLES FOR RNA THERAPEUTICS - Compounds comprising condensed particles having diameters less than 1000 nm, wherein the particles comprise one or more double stranded ribonucleic acids (dsRNAs) and one or more peptides. The compounds, compositions and methods are useful for modulating gene expression by RNA interference. | 2013-03-21 |
20130072425 | SAPOSIN-A DERIVED PEPTIDES AND USES THEREOF - The invention relates to isolated peptides and chimeric polypeptides derived from Saposin A that have anti-angiogenic activity. These peptides are small, consisting essentially of at least 10 consecutive amino acid residues from the 31st-50 | 2013-03-21 |
20130072426 | DIAGNOSTIC METHODS FOR OBESITY AND RELATED DISORDERS - Methods for detecting the presence of auto-antibodies to antigens expressed by adipose tissue are provided. Also provided are methods for diagnosing, prognosing and treating obesity and/or metabolic syndrome. | 2013-03-21 |
20130072427 | GPR 119 MODULATORS - Compounds of formula (I) that modulate the activity of the G-protein-coupled receptor GPR119 and their uses in the treatment of diseases linked to the modulation of the G-protein-coupled receptor GPR119 in animals are described herein. | 2013-03-21 |
20130072428 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency - The present invention discloses the signaling pathway involved erythroid repression by iron deficiency. Further disclosed is anon-toxic small-molecule compound which potently reverses the erythroid repression caused by iron deficiency. The present invention further encompasses novel compounds for inhibition of red cell production, useful, for example, in the treatment of polycythemia vera, a malignancy causing uncontrolled red cell production. These inhibitory compounds also promote megakaryocytic lineage commitment and may therefore be useful for augmentation of platelet production. The present invention further discloses isocitrate reversal of iron deprivation. | 2013-03-21 |
20130072429 | ASSAYS AND METHODS USING BIOMARKERS - Methods and assays examining expression of one or more biomarkers in a mammalian tissue or cell sample are provided. According to the disclosed methods and assays, detection of the expression of GalNac-T related molecules, such as GalNac-T14 or GalNac-T3, is predictive or indicative that the tissue or cell sample will be sensitive to apoptosis-inducing agents such as Apo2L/TRAIL and anti-DR5 agonist antibodies. Kits and articles of manufacture are also provided. | 2013-03-21 |
20130072430 | METHODS FOR TREATMENT OR PROPHYLAXIS OF KIDNEY OR LIVER DYSFUNCTION - Methods are provided for treatment or prophylaxis of liver or kidney dysfunction in individuals experiencing one or more of intestinal failure, short bowel syndrome or parenteral nutrition by the administration of GLP-2 or GLP-2 analogs. | 2013-03-21 |
20130072431 | CARDIOVASCULAR THERAPEUTICS - Compounds and compositions comprising a B-type natriuretic signal peptide fragment agent, and methods of use thereof, are provided for the treatment or prevention of cardiovascular diseases, disorders, and conditions. | 2013-03-21 |
20130072432 | PTD-UQCRB FUSION POLYPEPTIDE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ISCHEMIC DISEASES, CONTAINING SAME - A PTD-UQCRB fusion polypeptide, and a pharmaceutical composition for preventing and treating ischemic diseases, containing the same. The PTD-UQCRB fusion polypeptide of the present invention very effectively passes through a cell membrane to induce angiogenesis and does not cause cytotoxicity, and is thus useful for preventing and treating ischemic diseases. | 2013-03-21 |
20130072433 | INHIBITORS OF BETA INTEGRIN-G PROTEIN ALPHA SUBUNIT BINDING INTERACTIONS - Provided herein are compounds that inhibit a binding interaction between a β integrin and a G protein subunit, as well as compositions, e.g., pharmaceutical compositions, comprising the same, and related kits. In some embodiments, the compound is an antibody or antibody analog, and, in other embodiments, the compound is a peptide or peptide analog. Also provided are methods of using the compounds, including methods of treating or preventing a medical condition, such as stroke, heart attack, cancer, or inflammation. | 2013-03-21 |