12th week of 2013 patent applcation highlights part 39 |
Patent application number | Title | Published |
20130071430 | MICRORNA-CONTROLLED RECOMBINANT VACCINIA VIRUS AND USE THEREOF - It is intended to provide a vaccinia virus that specifically proliferates in a cancer cell and destroys the cancer cell and to provide use of the virus in cancer treatment. The present invention provides a microRNA-controlled vaccinia virus, in which a target sequence of a microRNA less expressed in a cancer cell than in a normal cell is inserted in a 3′ untranslated region of B5R gene associated with viral proliferation in a vaccinia virus, wherein the microRNA-controlled vaccinia virus specifically proliferates in the cancer cell and has an oncolytic property that destroys the cancer cell. | 2013-03-21 |
20130071431 | Method for Preserving Polypeptides Using A Sugar and Polyethyleneimine - The invention relates to the preservation of an active agent, such as a polypeptide, by contacting the active agent with a preservation mixture including a sugar and polyethyleneimine. | 2013-03-21 |
20130071432 | COMBINATION VIROTHERAPY FOR CANCER - One aspect of the present disclosure relates to a method for treating a subject with cancer. The method includes administering an oncolytic virus simultaneously, sequentially, or separately in combination with an immunomodulatory agent in an amount effective to suppress both antiviral immunity and angiogenesis associated with the cancer. | 2013-03-21 |
20130071433 | Interferon- Production Modulating Listeria Strains and Methods for Using Same | 2013-03-21 |
20130071434 | Campylobacter Polypeptides and Methods of Use - The present invention provides isolated metal regulated polypeptides obtainable from a | 2013-03-21 |
20130071435 | NOVEL HERBAL FORMULATION FOR THE MODULATION OF IMMUNE SYSTEM OF HIV INFECTED PATIENTS AND A PROCESS OF PREPARATION THEREOF - An herbal formulation for the modulation of immune system of HIV infected patients and a process of preparation thereof are provided. The process includes (i) preparing a hydromethanolic extract of at least one plant selected from Hippophae rhamnoides, | 2013-03-21 |
20130071436 | TREATMENT OF T-CELL MEDIATED DISEASES - The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions. | 2013-03-21 |
20130071437 | IMMUNOLOGICAL FUNCTION ENHANCING AGENT - An agent, as an active ingredient thereof, includes activated lymphocytes derived from a tissue of an animal, in which antibodies and immunocytes do not pass from a mother to a fetus across the placenta, and which is used to enhance the immunological functions of another animal of the same species as the animal from which the lymphocytes are derived. A method for producing an agent for enhancing immunological functions of another animal, in which lymphocytes isolated from an animal are grown and activated to produce activated lymphocytes. | 2013-03-21 |
20130071438 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HYPERPLASIA - In accordance with the present invention, there are provided methods for treating hyperplasia in a subject in need thereof. In another aspect of the invention, there are provided methods for reducing neointimal hyperplasia associated with vascular interventional procedures. Formulations contemplated for use herein comprise proteins and at least one pharmaceutically active agent. | 2013-03-21 |
20130071439 | METHODS AND COMPOSITIONS FOR TREATING BIOFILMS - Methods of treating or reducing biofilms, treating a biofilm-related disorder, and preventing biofilm formation using D-amino acids are described. | 2013-03-21 |
20130071440 | USE OF SIMPLE AMINO ACIDS TO FORM POROUS PARTICLES - Particles having a tap density of less than 0.4 g/cm | 2013-03-21 |
20130071441 | CELL CONSTRUCT FOR CELL TRANSPLANTATION AND CELL AGGREGATE FOR CELL TRANSPLANTATION - An object of the present invention is to provide a cell construct for cell transplantation capable of having a thickness suitable for cell transplantation, preventing the necrosis of transplanted cells, and forming blood vessels in the transplantation site after transplantation. The present invention provides a cell construct for cell transplantation which comprises polymer blocks having biocompatibility and cells of at least one type, wherein the plural polymer blocks are arranged in spaces between the plural cells. | 2013-03-21 |
20130071442 | Aerosolized Fosfomycin/Aminoglycoside Combination for the Treatment of Bacterial Respiratory Infections - A fosfomycin plus tobramycin combination formulation for delivery by aerosolization is described. The concentrated fosfomycin tobramycin combination formulation containing an efficacious amount of fosfomycin plus tobramycin is able to inhibit susceptible bacteria. Fosfomycin and tobramycin are formulated separately in a dual ampoule such that when reconstituted, the pH is between 4.5 and 8.0 or as a dry powder. The method for treatment of respiratory tract infections by a formulation delivered as an aerosol having mass medium average diameter predominantly between 1 to 5μ, produced by a jet or ultrasonic nebulizer (or equivalent) or dry powder inhaler. | 2013-03-21 |
20130071443 | Glycosaminoglycans - Heparan sulphate HS7 is disclosed, together with the use of HS7 in the growth and/or development and/or regeneration of tissue. | 2013-03-21 |
20130071444 | Amphiphilic Cationic Polymers and Methods of Use Thereof - Amphiphilic cationic polymers comprising a biocompatible amphiphile linked to an organic cation are provided. The polymers complex with therapeutic agents and facilitate delivery of such therapeutic agents, particularly therapeutic nucleic acids, both in vitro and in vivo. Accordingly, the invention further provides methods of facilitating delivery of therapeutic and/or diagnostic agents to a cell and methods of treating a condition, such as a disease or infection, in an organism using the amphiphilic cationic polymers of the invention. | 2013-03-21 |
20130071445 | TRANSLUMINAL DRUG DELIVERY METHODS AND DEVICES - Transluminal drug delivery method and device embodiments can include a urethral suppository formulated to prevent or treat diseases of the urethra and surrounding organs, such as interstitial cystitis or urethritis, by enhancing the absorption of a therapeutic agent of the suppository into body tissues without adversely affecting the natural defense mechanisms of these tissues. Adverse effects on the glycosaminoglycan (GAG) barrier can be mitigated or eliminated by the presence of a suitable polysaccharide in the suppository. | 2013-03-21 |
20130071446 | INFANT NUTRITION FOR IMPROVING FATTY ACID COMPOSITION OF BRAIN MEMBRANES - The present invention relates to infant nutrition, in particular to infant nutrition comprising special lipid globules for improvement of the fatty acid composition in brain membranes. | 2013-03-21 |
20130071447 | METHODS FOR PRODUCING ECM-BASED BIOMATERIALS - A method for forming an extracellular matrix material (ECM) material includes providing at least an ECM composition containing ECM particles varying in their capacity for migration through a fluid medium, including at least one population of expanded ECM particles. The ECM composition is combined in a fluid medium to form a flowable ECM composition. The flowable ECM composition is subjected to a centrifugal force in a mold for a period of time sufficient to distribute the ECM particles according to differences in their physical characteristics. The ECM composition is dried to form a dried ECM material having a density gradient extending from a less dense region to a more dense region. The dried ECM material may formed as a porous, substantially acellular ECM material expandable in an aqueous fluid environment by at least 100% in volume. | 2013-03-21 |
20130071448 | TREATMENT OF T-CELL MEDIATED DISEASES - The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions. | 2013-03-21 |
20130071449 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS - An implantable device including a conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided. | 2013-03-21 |
20130071450 | GELS FOR TRANSDERMAL DELIVERY - The present disclosure provides hydrogels that are suitable for drug delivery. In embodiments, hydrogels of the present disclosure may be used for transdermal delivery of bioactive agents, including drugs. The hydrogels of the present disclosure may also be useful as conductive compositions for use with electrodes. | 2013-03-21 |
20130071451 | CAROTENOID-CONTAINING COMPOSITION AND PRODUCTION METHOD THEREOF - A method of producing a carotenoid-containing composition including: obtaining a carotenoid-containing oil phase composition by heating an oil phase component mixed liquid containing a carotenoid component containing at least one crystalline carotenoid, and a (poly)glyceryl fatty acid ester having form 1 to 6 of a glycerin unit and from 1 to 6 of a fatty acid unit and in which the glycerin unit has at least one hydroxyl group, at a dissolution temperature of the carotenoid component or higher; and obtaining an oil-in-water emulsified composition by emulsifying under pressure the carotenoid-containing oil phase composition with an aqueous-phase composition comprising an emulsifying agent. | 2013-03-21 |
20130071452 | PHARMACEUTICAL COMPOSITION COMPRISING AMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF - The present invention relates to a pharmaceutical composition comprising an amide derivative or a pharmaceutically acceptable salt thereof, and an acidic additive. This composition, owing to improved stability even after a long-term storage, is suitable for inhibiting the growth of cancer cells. | 2013-03-21 |
20130071453 | Compositions Comprising Solid Particles Entrapped In Collapsed Polymeric Microspheres, And Methods Of Making The Same - The present invention relates to topical compositions containing solid particles that are stabilized via entrapment by microspheres and methods for making the same. Each of the microspheres contains a collapsed polymeric shell that has entrapped therein one or more solid particles. The solid particles are preferably formed of zinc oxide or titanium dioxide or both, which can readily be used either alone or in combination with other sunscreen agents to form sunscreen compositions of broader UV protection spectrum and enhanced photostability. | 2013-03-21 |
20130071454 | BREATH FRESHENING CONFECTIONERY PRODUCTS AND METHODS OF MAKING AND USING SAME - A confectionery product comprises a first side and a second side generally opposite to the first side; the second side comprising an abrasive surface that is suitable for scrubbing the top surface of a tongue within the oral cavity. In preferred embodiments the first side is smooth, and may be domed shaped and generally fit the roof of the mouth. The abrasive surface may be provided by 1) a formed, uneven surface, 2) by including abrasive particles in the composition making up the second surface, or 3) a combination of a formed, uneven surface and abrasive particles. The confectionery product is preferably a hard confectionery, but may also be a chewing gum product. A preferred confectionery product comprises a second side with a width and a length, the smallest of which is at least 1.6 times the product thickness. Preferred pressed tablets are made from a compressible composition and have at least one abrasive surface suitable for cleaning the surface of a human tongue in an oral cavity and have a hardness of between about 18 Kp and about 35 Kp. | 2013-03-21 |
20130071455 | SOLID CORE COACERVATED CAPSULES - Coacervated capsules that have from 10 to 99% by weight of the capsule of a core comprising a mixture of (I) a fatty component of (i) hydrogenated oil or (ii) hydrogenated fat or (iii) cocoa butter or (iv) a mixture thereof and (II) a material to be encapsulated comprising a flavor and/or fragrance material, the mixture having a Tm of between about 30° C. and about 40° C. such that it is a solid at 20° C., wherein the weight ratio of fatty component to material to be encapsulated is from to 10:90 to 70:30, and from 90 to 1% by weight of the capsule of a coating layer of a protein, and optionally a non-protein polymer. Also, methods of manufacture and use of such capsules and food and oral care compositions containing such capsules. | 2013-03-21 |
20130071456 | ENCAPSULATION OF INGREDIENTS IN LACTOSE MATRIX TO FORM ACTIVE ENCAPSULATES - An oral care composition and method are described in which the composition includes lactose matrix encapsulates entrained in a carrier. The encapsulates may further comprise oral care and/or personal care ingredients. | 2013-03-21 |
20130071457 | Wound Healing Device - The invention is directed to a wound healing device. Such wound healing device utilizes novel wound healing compositions embedded onto or into a natural plant-derived cloth-based matrix. | 2013-03-21 |
20130071458 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS - Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent. | 2013-03-21 |
20130071459 | FORMULATIONS EMPLOYING ANHYDROUS DISINFECTANT - Use of dried compositions of silver dihydrogen citrate along with citric acid in antimicrobial amounts directly as disinfectants is described. | 2013-03-21 |
20130071460 | Novel Pesticidal Composition - The present invention relates to an agricultural composition comprising sulphur in the range from 20% to 80% of the total composition, a chloronicotinyl compound in the range from 0.7% to 25% of the total composition, a pyrethroid compound in the range from 0.75% to 10% of the total composition and at least one agrochemically acceptable excipient | 2013-03-21 |
20130071461 | METHODS EMPLOYING ANHYDROUS DISINFECTANT - Use of dried compositions of silver dihydrogen citrate along with citric acid in antimicrobial amounts directly as disinfectants is described. | 2013-03-21 |
20130071462 | Drug Delivery Systems and Applications - Certain embodiments of the invention include medical materials and methods comprising a biodegradable hydrophilic hydrogel comprising dispersed lipophilic particles that comprise a therapeutic agent, wherein the lipophilic particles have a low water solubility in physiological saline at physiological temperature. | 2013-03-21 |
20130071463 | IMPLANTS FOR POSTOPERATIVE PAIN - Medical implants and methods useful in treating postoperative pain are described. The implants comprise one or more electrospun drug-loaded fibers, which fibers comprise a drug useful in the treatment of pain. The implants are implanted at sites of interest including joint capsules, bones, and subcutaneous spaces, and are secured with tissue flaps or fasteners. | 2013-03-21 |
20130071464 | COMPOSITION COMPRISING PHOSPHONIC ACID POLYMER FOR USE AS TISSUE ENGINEERING FIBROUS SCAFFOLD - A fibrous tissue scaffold wherein fibres of the scaffold comprise a phosphonic acid polymer. The fibres preferably incorporate a vinylphosphonic acid—acrylic acid copolymer, and may further include polycaprolactone. There is further described medical implant coating comprising a phosphonic acid polymer, a biocompatible fibre comprising a phosphonic acid polymer and a biocompatible polymer comprising polycaprolactone and a phosphonic acid polymer. | 2013-03-21 |
20130071465 | ACTIVATED LEUKOCYTE COMPOSITION AND USES FOR WOUND HEALING - Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds. | 2013-03-21 |
20130071466 | METHODS AND COMPOSITIONS FOR TREATING GASTRIC DISORDERS - Improved efficacy in treatment of gastric disorders with botulinum toxin is obtained using liposomal encapsulated botulinum formulations for topical administration of the botulinum toxin. The liposomes are typically administered in a physiologically acceptable carrier such as saline or phosphate buffered saline by application onto the surface of the tissue within into the gastrointestinal (GI) tract in need of treatment. Preferably, the formulation is applied via a roller, sponge or nozzle that is attached to an endoscope. | 2013-03-21 |
20130071467 | RETINOID-LIPOSOMES FOR TREATING FIBROSIS - What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1_2 (SEQ ID NOS: 60 and 127), SERPINH1_45a (SEQ ID NOS: 98 and 165), and SERPINH1_51 (SEQ ID NOS: 101 and 168), and drug carrier comprising a mixture of a retinoid and a lipid vesicle, and methods of using these pharmaceutical compositions to treat a disease associated with hsp47 expression, including fibrosis. | 2013-03-21 |
20130071468 | Lipid-Based Compositions of Antiinfectives for Treating Pulmonary Infections and Methods of Use Thereof - A system for treating or providing prophylaxus against a pulmonary infection is disclosed comprising: a) a pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition, and b) an inhalation delivery device. A method for providing prophylaxis against a pulmonary infection in a patient and a method of reducing the loss of antiinfective encapsulated in a lipid-based composition upon nebulization comprising administering an aerosolized pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition is also disclosed. | 2013-03-21 |
20130071469 | Lipid-Based Compositions of Antiinfectives for Treating Pulmonary Infections and Methods of Use Thereof - A system for treating or providing prophylaxus against a pulmonary infection is disclosed comprising: a) a pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition, and b) an inhalation delivery device. A method for providing prophylaxis against a pulmonary infection in a patient and a method of reducing the loss of antiinfective encapsulated in a lipid-based composition upon nebulization comprising administering an aerosolized pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition is also disclosed. | 2013-03-21 |
20130071470 | Fenugreek Seed Extract to Lower Blood Cholesterol - A method of lowering blood cholesterol in a non-diabetic patient by at least 30% is described. The method involves orally administering for 30 consecutive days a fenugreek seed extract composition. Various methods of preparation and various formulations are described. Physiologically effective pharmaceutical compositions and beverages containing fenugreek seed extracts and other active components are also disclosed. | 2013-03-21 |
20130071471 | PHARMACEUTICAL COMPOSITION FOR TREATING ATOPIC DERMATITIS - A method of treating mild atopic dermatitis patients by locally administering an external composition containing adenosylcobalamin as an active ingredient is provided. The composition can effectively treat mild atopic dermatitis patients without side effects. | 2013-03-21 |
20130071472 | Fascile synthesis of biocompatible polymer capsule nanoparticles for drug encapsulation - The present invention relates to a method for preparing a capsule nanoparticle used in encapsulating hydrophobic medicines, comprising the following steps: (A) providing a biocompatible polymer and an organic solution containing a hydrophobic medicine; (B) stirring the organic solution at 3-10° C., and titrating with an alcohol solution, so as to make the biocompatible polymer encapsulate hydrophobic medicine to form a capsule nanoparticle; (C) ultrasonic vibrating the capsule nanoparticle at 3-10° C.; (D) filtering the capsule nanoparticle to an average size controllable in the range of 60-450 nm; and (E) lyophilizing the encapsulated particles. | 2013-03-21 |
20130071473 | COMPOSITION AND METHOD FOR TREATING ULCERS - The composition for the treatment of ulcers includes ground charcoal, ground mustard seed and an edible salt dissolved or suspended in an edible oil. A single effective therapeutic dosage of the composition includes approximately 4,000 mg of the ground charcoal, approximately 2,500 mg of the ground mustard seed, approximately 550 mg of the edible salt, and approximately 15 ml of the edible oil. The effective therapeutic dosage is delivered to the patient orally, and may be provided to the patient as a tablet or capsule, or as a liquid mixture. | 2013-03-21 |
20130071474 | COMBINATIONS OF BERBERINE, ARTEMISININ, Loperamide AND THEIR DERIVATIVES TO TREAT MALARIA, DIARRHEA, TRAVELERS' DIARRHEA, DYSENTERY, DENGUE FEVER, PARASITES, CHOLERA AND VIRUSES - This invention relates to compositions and methods of combining berberine, artemisinin and loperamide or their derivatives in a therapeutic product for mammals suffering from malaria, diarrhea, travelers' diarrhea, dysentery, dengue fever, parasites, cholera and viruses by administration of a therapeutically effective amount of the composition. | 2013-03-21 |
20130071475 | Method For Producing An Oral Pharmaceutical Form With Immediate Disintegration And Active Ingredient Release - The invention relates to a method for producing an oral form of administration which decomposes immediately and releases active ingredients in the mouth. According to said method, (a) an anionic pharmaceutical active ingredient is intensively mixed with (b) a copolymer consisting of radically polymerized C | 2013-03-21 |
20130071476 | Rapid Melt Controlled Release Taste-Masked Compositions - Rapid melt tablets that dissolve and release an active component in the oral cavity are comprised of a pharmaceutical active ingredient such as dextromethorphan complexed with a resin that is effective in taste-masking the otherwise bitter taste of the active making it convenient for oral administration. The drug/resin-complexed particles can be coated with water swellable or water insoluble polymers to impart controlled release properties to the active ingredient. A rapid melt tablet also comprises diluents, sweeteners, flavors, disintegrants and other excipients to form granules that can be compressed into tablets at low pressure without the need for a binding agent. | 2013-03-21 |
20130071478 | RETINOID-LIPOSOMES FOR ENHANCING MODULATION OF HSP47 EXPRESSION - What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH | 2013-03-21 |
20130071479 | Microspheres - The disclosure relates to substantially uniform, high density microspheres and methods of making the microspheres. The microspheres can be made to be small in size with a narrow range of particle size distribution and a high sphericity. In one aspect, the microspheres provided herein are provided in the form of spherical cores comprising maltodextrin or maltodextrin and starch and are prepared using a centrifugal tumbling-granulating-coating apparatus. In another aspect, the spherical cores can be powder-coated with one or more layers of small particles, such as starch particles. The microspheres provided herein can be used as cores for multi-particulate solid dosage delivery systems as well as other pharmaceutical, nutraceutical, food, personal care, and other applications. | 2013-03-21 |
20130071480 | Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances - Particles having a core based on at least one biodegradable organosoluble polymer. At least a part of the surface of the particles is coated with at least one hyaluronan or a derivative thereof, the hyaluronan being a water-soluble, amphiphilic hyaluronan of which the carboxylic functions are in part transformed to form hydrophobic groups. | 2013-03-21 |
20130071481 | COATED PARTICLE AND METHOD FOR PRODUCING COATED PARTICLE - The present invention relates to a coating particle containing a nuclear particle covered with a coating layer, and in the coating particle, the coating layer is a layer containing hydroxyalkyl cellulose and a binder. | 2013-03-21 |
20130071482 | BLOCK COPOLYMER CROSS-LINKED NANOASSEMBLIES AS MODULAR DELIVERY VEHICLES - A nanoassembly includes a core protected by a biocompatible shell. The nanoassembly includes a plurality of block copolymers including drug-binding linkers and block copolymer cross-linkers. A first active agent is covalently conjugated to the plurality of block copolymers and a second active agent is physically entrapped in the core. | 2013-03-21 |
20130071483 | VACCINE PRODUCED USING OPTIMIZED IMMOBILIZATION ANTIGEN cDNA OF CRYPTOCARYON IRRITANS AND PRODUCING METHOD AND USE THEREOF - The present invention provides an optimized immobilization antigen cDNA sequence of | 2013-03-21 |
20130071484 | Self-Assembled Toroidal-Spiral Particles and Manufacture and Uses Thereof - Toroidal-spiral shaped particles, their method of manufacture, and uses thereof are disclosed. The toroidal-spiral particles can contain at least one active agent, such as a drug, and provide a controlled, sustained release of the active agent. | 2013-03-21 |
20130071485 | ORGANIC LUBRICANT - A vaginal lubricant of primarily organic materials has excellent properties for relieving vaginal dryness. | 2013-03-21 |
20130071486 | ACELLULAR TISSUE MATRICES MADE FROM ALPHA-1,3-GALACTOSE-DEFICIENT TISSUE - The invention provides acellular tissue matrices made from collagen-containing tissues of animals genetically modified so as to be deficient in the galactose 1,3-galactose epitope and methods of making and using such acellular tissue matrices. | 2013-03-21 |
20130071487 | XENON-BASED INHALABLE DRUG FOR PREVENTING ADDICTION RELAPSES IN HUMANS - The invention relates to a gas composition containing xenon gas for use in preventing the relapse of a patient who has been weaned from at least one psychotropic product which resulted in said patient becoming habituated, the xenon being administered to the patient by inhalation. The composition of the invention contains an effective volume proportion of xenon, in particular from 5 to 70% by volume of xenon. DRAWING: FIG. | 2013-03-21 |
20130071488 | DISINFECTANT COMPOSITION FOR HARD ARTICLES, AND METHOD FOR DISINFECTING OF SURFACE OF HARD ARTICLE - Disclosed are a two-agent type disinfectant composition for hard articles, which includes a first agent containing a powder mixture (A) and a second agent containing an aqueous hydrogen peroxide solution (B-1), the powder mixture (A) containing an alkali metal salt (A-1) exhibiting basicity when the salt is in the form of an aqueous solution, a water-soluble copper salt (A-2), a compound (A-3) represented by the following formula (1), and a nonionic surfactant (A-4) represented by the following formula (2), and in which the molar ratio of the water-soluble copper salt (A-2) and the compound (A-3) represented by the mixing amount of (A-3)/mixing amount of (A-2) is 3.0 to 20; and a single-agent type disinfectant composition for hard articles, which includes the components (A-1) to (A-4), and an inorganic peroxide (B-2) that releases hydrogen peroxide in water, and in which the molar ratio of the water-soluble copper salt (A-2) and the compound (A-3) represented by the mixing amount of (A-3)/mixing amount of (A-2) is 3.0 to 20. Disinfectant compositions for hard articles which have high disinfecting power against the surfaces of hard articles, have satisfactory stability of hydrogen peroxide in water, and have low foaming tendency, and a method for disinfecting the surface of a hard article by using the disinfectant composition for hard articles, can be provided. | 2013-03-21 |
20130071489 | METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA - Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier. | 2013-03-21 |
20130071490 | X-RAY CONTRAST MEDIA COMPOSITIONS AND METHODS OF USING THE SAME TO TREAT, REDUCE OR DELAY THE ONSET OF CNS INFLAMMATION AND INFLAMMATION ASSOCIATED CONDITIONS - Embodiments disclosed herein relate to improved X-ray contrast media compositions and methods of using the same for treating symptoms related to allergic reactions, inflammatory conditions, symptoms of the common cold and certain cancers. | 2013-03-21 |
20130071491 | Extruded Legume Food Products Containing Yeast Autolysate - An extrusion process for producing a uniform and highly expanded food product is disclosed with nutritional yeast and chromium. The uniform expansion ratio possessed by the extruded product provides a consistent texture and has application in a wide variety of food consumables, ranging from snacks to breakfast cereals. | 2013-03-21 |
20130071492 | SYSTEMS AND METHODS FOR GENERATING GERMICIDAL COMPOSITIONS - The present invention relates to systems and methods for generating germicidal compositions for use in a wide variety of settings, including agricultural settings, food production settings, hospitality settings, health care settings, health club settings, exercise facility settings, research based settings, veterinarian settings, medical settings, hydraulic fracturing settings, and/or any setting requiring disinfection. | 2013-03-21 |
20130071493 | Dietary supplement containing alkaline electrolyte butters - An improved dietary and/or therapeutic supplement composition comprising a quantity of a dietary and/or therapeutic supplement agent having a pH that upon ingestion with food or a beverage would limit the effectiveness of the agent and a sufficient amount of an alkaline electrolyte additive is provided in combination with the agent to raise the pH of the composition to a level of from about 8 to about 12.5 to increase the effectiveness and functional utilization of the agent while the composition is in the person's stomach. In a preferred composition, the electrolyte additive is selected from the group consisting of calcium, magnesium and potassium electrolytes. The supplement composition may be in the form of tablet, capsule, powder or liquid forms. The supplement composition is designed to provide for optimum utilization of a dietary and/or therapeutic supplement agent when taken orally with food or a beverage. | 2013-03-21 |
20130071494 | NITRITE FORMULATIONS AND THEIR USE AS NITRIC OXIDE PRODRUGS - Compositions comprising from about 40 weight parts to about 1000 weight parts of a botanical nitrate source; from about 20 weight parts to about 500 weight parts of a botanical source of nitrite reduction activity; and from about 4 weight parts to about 100 weight parts of a nitrite salt. Use of said composition in methods of reducing triglycerides or reducing C-reactive protein levels are also provided. | 2013-03-21 |
20130071495 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR USE IN THERAPEUTIC METHODS AND SCREENING METHOD RELATING THERETO - The present invention relates to an inhibitor of glycogen synthase kinase 3 (GSK-3) for use in a method of treating or preventing emphysema, a method of activating an emphysema cell, an activated emphysema cell obtained by this method for use in a method of treating or preventing emphysema, and a method of screening for a substance for treating or preventing emphysema. | 2013-03-21 |
20130071496 | CONTROLLED RELEASE COMPOSITION CONTAINING A STRONTIUM SALT - A controlled release pharmaceutical composition comprising a strontium salt. The invention also relates to the use of a strontium salt for treating a male suffering from diseases and conditions affecting metabolism and/or structural integrity of cartilage and/or bone. The invention also relates to the use of a strontium-containing compound for preventing a cartilage and/or bone condition in a subject, and for the treatment and/or prophylaxis of secondary osteoporosis. | 2013-03-21 |
20130071497 | Formulations and Methods for Preventing Eyebrow Hair Loss - Compositions comprising from about 0.5 to about 40 percent by weight of black cohosh extract, from about 0.5 to about 20 percent by weight of nonionic surfactant, and from about to 40 about 99 percent by weight of hydroxylated solvent are effective in reducing and preventing eyebrow hair loss in patients undergoing chemotherapy. | 2013-03-21 |
20130071498 | Insecticidal Compositions and Uses Thereof - The present invention provides compositions and methods for controlling plant pests. In particular, the present invention provides plant extracts with insecticidal activity. | 2013-03-21 |
20130071499 | COMPOSITION FOR TREATING INFLAMMATORY, ALLERGIC OR ASTHMA DISEASES, CONTAINING PAPRIKA EXTRACTS - The present invention relates to a composition containing a paprika extract as an active ingredient, and more particularly to a pharmaceutical composition or health functional food for preventing or treating inflammatory, allergic or asthma disease, which contains a paprika extract. Particularly, paprika is a natural food which is readily available to anyone, and thus does not cause adverse effects even when it is taken for a long period of time. | 2013-03-21 |
20130071500 | COMPOSITIONS AND METHODS FOR TREATING SIGNS OF SKIN AGING - The invention relates to methods and compositions for treating skin aging, said compositions comprising at least one tropoelastin promoter and at least one tropoelastin crosslinker. | 2013-03-21 |
20130071501 | EXTRACT OF STEWARTIA KOREANA AND USE THEREOF - The present invention relates to an extract of | 2013-03-21 |
20130071502 | COMPOSITIONS FOR SKIN DISEASE OR DISORDERS - Medicaments or cosmetic compositions for the treatment or alleviation of skin or mucous membrane diseases or disorders related to an enhanced level of anti-microbial peptides or proteins comprising | 2013-03-21 |
20130071503 | Device and Tool for Cold Expansion of Fastener Holes - The invention refers to a device and a tool for cold expansion of fastener holes. The advantages of the device and tool are in the possibility to control the degree of cold expansion. The device ( | 2013-03-21 |
20130071504 | TIRE VULCANIZER AND METHOD FOR TRANSPORTING OR PACKAGING THE SAME - Provided are a tire vulcanizer and a method for transporting or packaging the same whereby, even in cases where the overall height direction dimension of the vulcanizer exceeds size limits for domestic transportation or export packaging, the vulcanizer can easily clear said limits and be transported or packaged. A tire vulcanizer comprising tie rods extending upward from a base plate, said tie rods receiving squeezing force applied to a bolster plate and a top mold when vulcanizing a tire and guiding lifting/lowering of the bolster plate and the top mold when opening and closing the top mold. In such a tire vulcanizer, the tie rods are configured so as to be vertically dividable into at least two or more sections at a position in the length direction thereof. | 2013-03-21 |
20130071505 | MOLDING DEVICE FOR SEMICONDUCTOR CHIP PACKAGE - A molding device for a semiconductor chip package includes a first molding die, a second molding die opposite to the first molding die and a plurality of pistons. The second molding die defines a plurality of cylinders for receiving the corresponding pistons. The first molding die and the second molding die collectively form a molding cavity to accommodate a substrate. The first molding die includes a protruding portion defining a groove opening towards the second molding die. The protruding portion and the second molding die collectively form an entrance and an exit on two sides of the groove. Each of the plurality of pistons is compressed to force a molding compound flowing through the entrance, the groove and the exit to fill into the molding cavity so as to encapsulate the substrate. | 2013-03-21 |
20130071506 | MATERIAL FORMING APPARATUS - The present invention is a material forming apparatus that includes a piece of material that is a piece of laminated wood, a cover sheet made of plastic material, a flexible bed, a plurality of bed arms and a plurality of drive gears. The material forming apparatus also includes a numerical digital display, a plurality of roller clamps, one or more cranks with a grasping knob and a plurality of pivoting arms that are rotated by rotation of the drive gears and move the bed arms to force the flexible bed and the piece of material into a desired arc radius. | 2013-03-21 |
20130071507 | STEERABLE LASER PROBE - A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a housing sleeve disposed in an inner bore of the handle configured to project a distance from the handle distal end, an optic fiber disposed in the housing sleeve, a shape memory sleeve disposed over a distal end of the optic fiber, and a light source configured to connect to a proximal end of the optic fiber. The shape memory sleeve may be configured to curve the distal end of the optic fiber at an angle, e.g., 90 degrees, when the shape memory sleeve is not contained within the housing sleeve. | 2013-03-21 |
20130071508 | HOT ISOTROPIC PRESSURE DEVICE - A hot isotropic pressure device including: a casing disposed inside a high-pressure container; a heating unit provided inside the casing and forms a hot zone around the treatment material, in which an isotropic pressure treatment is performed on the treatment material using a pressure medium gas. A cooling unit is provided to cool the hot zone by guiding the pressure medium gas, cooled while guided from the upper side toward the lower side at the outside of the casing, into the hot zone. The cooling unit includes a gas introducing unit which guides the pressure medium gas cooled at the outside of the casing from the lower portion of the high-pressure container to the upper portion of the hot zone without any intersection with the pressure medium gas inside the hot zone and introduces the pressure medium gas into the hot zone. | 2013-03-21 |
20130071509 | MOULD FOR MOULDED PARTS WITH INTERNAL UNDERCUTS - Mould for moulded parts with internal undercuts that comprises a core of the mould with two complementary parts (both fitted one inside the other), providing the possibility of axial displacement and turning among them, establishing the external element part various slots where the parallel forms that the internal element part has in its peripheral area are inserted. Thus, thanks to the axial displacement and the turning of both elements, the parallel forms come out of from the slots and deviate from the coping enabling the ejection of the moulded part without being forced. | 2013-03-21 |
20130071510 | INJECTION DEVICE IN MOLDING MACHINE - A injection device in molding machine is capable of efficiently heating and melting a plurality of charged pellets in a short period of time, and injecting a melting resin with superior quality. | 2013-03-21 |
20130071511 | METHOD OF MANUFACTURING A MOLD WITH CONFORMAL COOLING PASSAGES AND MOLD MANUFACTURED ACCORDING TO SAID METHOD - A method of producing at least one conformal cooling passage in a part-producing mold, and a mold provided with such a conformal cooling passage(s). A conformal cooling passage is produced by creating an open channel in a molding surface of a mold of interest, the channel substantially conforming to the contour of the molding surface. A bridging weld formed from a plurality of connected weld beads is generated in the channel so as to span and seal the channel while enclosing an open passage in the bottom thereof. The remainder of the channel above its bridging weld is filled, such as by welding, and an exposed portion of the fill material in the channel may be subsequently shaped to conform with the contours of the molding surface surrounding the channel. A sub-surface conformal cooling passage is thus formed in the mold. | 2013-03-21 |
20130071512 | OPENING DEVICE OF SLIDES IN MOULDS FOR THE EJECTION OF MOULDED PARTS - Opening device with slides in moulds to extract the moulded parts. The cavity is formed by mobile parts that can be removed to release the moulded parts. The cavity of the moulds is formed by slides that are installed on the corresponding holders that are fixed to the corresponding racks connected among them through a connection element, preferably a gear, and that are simultaneously activated with a driving element. | 2013-03-21 |
20130071513 | BEVERAGE ADDITIVES - We disclose a water-based solution containing xylitol that helps reduce the risk of dental problems. The solution may be pre-packaged in a readably consumable form, or it may be packaged as a concentrate that can be added to beverage at the time of consumption. In addition to xylitol, other additives may be added to the solution including fluoride, flavoring, vitamins, caffeine, carbonation, electrolytes, minerals, sugars, and sugar alcohols. | 2013-03-21 |
20130071514 | SLOW-RELEASE DIETARY FORMULATIONS - The present invention relates to dietary formulations for the slow release of water-soluble active ingredients. Said formulations comprise a coating obtained by evaporation from vinyl polymer dispersions not containing emulsifiers. The formulations can be advantageously included in an edible composition, including confectionery products. | 2013-03-21 |
20130071515 | NON-TACK GUM BASE, CHEWING GUM PREPARATION PRODUCED THEREFROM AND METHODS FOR PRODUCTION THEREOF - The invention relates to a non-tack gum base, a chewing gum preparation produced therefrom and also methods for production thereof. It is a homogeneous composition comprising polyvinyl acetate in an amount of 25-90% by weight, vinyl laurate-vinyl acetate copolymer in an amount of 5-70% by weight, and a softener in an amount of 1%-15% by weight, in each case based on the total weight of the composition. | 2013-03-21 |
20130071516 | COATED MULTI-REGION CONFECTIONERY AND METHODS OF MAKING THE SAME - Disclosed are particulate coated multi-region structures prepared from sugar free confectionery products and chewing gum. | 2013-03-21 |
20130071517 | COLLECTIBLE ITEM INCLUDING EDIBLE CONFECTIONARY IMAGE ITEM AND NOVELTY IMAGE ITEM - A collectible item comprising a novelty image item and an edible confectionary image item is provided. The novelty image item may contain an image that matches the image on the confectionary image item, or an image that is related to the image on the confectionary image item. A plurality of collectible image items may be provided on a sheet, and the collectible image items may be individually removable from the sheet. An intermediate layer may also be provided which separates the confectionary image item from the novelty image item. The collectible item may include stickers as the novelty image item, and may include gum with an image formed thereon as the confectionary image item. | 2013-03-21 |
20130071518 | METHOD FOR PRODUCING MEAT PRODUCTS AND MEAT PRODUCT PRODUCED BY SAID METHOD - The present invention relates to a method for producing meat products, in particular sausage, on the basis of substantially known recipes and basic principles of typical sausage varieties having a shortened ripening time, wherein, during processing, two ripening-accelerating mixtures of stabilizers, colorants and/or edible salts (ripening mixture 1) and spices, flavoring agents and/or thickeners (ripening mixture 2) are introduced simultaneously or successively into the raw meat mixture. | 2013-03-21 |
20130071519 | PROCESS FOR THE RECOVERY OF BETAINE FROM MOLASSES - A process for the recovery of betaine from a molasses comprises a conversion step, in which the molasses is subjected to the action of an enzyme having endo-inulinase activity and/or fructosyltransferase activity, to form a fructan-containing molasses (fructan-molasses); a separation step, in which the fructan-molasses is subjected to a chromatographic separation, thereby obtaining a betaine-containing fraction. | 2013-03-21 |
20130071520 | Method and System for Recovering and Preparing Glacial Water - Methods and systems for grouping, recovering, and processing ice obtained from an ice source, i.e., a glacier, ice sheet, ice cap, etc., are described herein. In particular, the ice obtained from the ice source is separated and grouped according to common unique properties and processed as a beverage for consumption having the same unique properties. | 2013-03-21 |
20130071521 | REBAUDIOSIDE D SWEETENERS AND FOOD PRODUCTS SWEETENED WITH REBAUDIOSIDE D - Beverage products are provided, e.g., a ready to drink cola beverage or a cola beverage concentrate or syrup, including water or carbonated water, acidulant comprising at least one acid, rebaudioside D present in a sweetening amount, and flavoring comprising cola flavoring. Rebaudioside D may be the only sweetener, or alternatively the beverage product further contains one or more additional sweeteners, for example rebaudioside A and/or other high intensity sweetener(s). Rebaudioside D optionally provides at least 10% of the total sweetening of the beverage product according to certain embodiments. Also, a natural carbonated cola beverage product and a beverage product are each provided containing a sweetening amount of rebaudioside D. The rebaudioside D ingredient used in certain methods of making the beverage products disclosed here optionally has a purity, i.e., a rebaudioside D concentration, of 93% or greater, such as 95% or greater, by weight. | 2013-03-21 |
20130071522 | Coffee Filter Pod - In one aspect, a coffee filter pod containing roast and ground coffee is provided wherein the roast and ground coffee has a plurimodal volume distribution density with a first peak of from 30 to 60 microns and a second peak of from 260 to 330 microns, wherein the ratio of the volume of the particles in the first peak relative to the volume of the particles in the second peak is from 2:1 to 1:2. In another aspect, a method of preparing a short coffee beverage is disclosed. A system for producing an espresso beverage and a method for producing a coffee filter pod are also provided. | 2013-03-21 |
20130071523 | SWEETENED FOOD PRODUCT AND METHODS OF PREPARATION - Described are coated food products having a sugar (sucrose) coating, the coating exhibiting desirable levels of sucrose crystallinity and a desired sucrose ratio (total sucrose per total soluble solids), as well as methods or preparing such coated food products and coating. | 2013-03-21 |
20130071524 | COATED FOOD PRODUCT AND METHODS - Described are food products such as ready to eat cereal having a base and a coating; examples include a base, a slurry layer over the base produced by applying a slurry coating to the base, the slurry layer having less than about 80% sucrose on a dry weight basis, and a particulate layer on the slurry layer. The particulate layer can be produced by dry charging particulates onto the slurry coated base. Particulates include be one or more of pregel starch, high molecular weight dextrin, high molecular weight soluble fiber, partially soluble fiber, insoluble fiber, protein, low solubility non-sugar compound, or sucrose, for example. | 2013-03-21 |
20130071525 | COATING FAT COMPOSITION AND PARTICULATE COMPOSITION USING THE SAME - A particulate composition, wherein a hydrophilic substance is polydispersed in a matrix of a fat composition having a solid fat content at 25 C of 58% or more and a solid fat content at 37 C of 90% or less; and a coating fat composition containing 45% by weight or more of a triglyceride comprising at least both a saturated fatty acid having 6 to 12 carbon atoms and a saturated fatty acid having 14 or more carbon atoms as constituent fatty acids, wherein the proportion of the saturated fatty acid having 14 or more carbon atoms in the constituent fatty acids of the whole fat exceeds 50% by weight. | 2013-03-21 |
20130071526 | ICE CONFECTION COMPRISING GELATIN - An ice confection comprising gelatin, locust bean gum and xanthan gum, a process for the manufacture of the ice confection and a frozen confectionery product comprising such ice confection are provided. A method of reducing foaming in the production of an ice confection comprising gelatin is also provided as is a use of a combination of locust bean gum and xanthan gum for reducing foaming in the production of an ice confection. | 2013-03-21 |
20130071527 | In-Package Non-Ionizing Electromagnetic Radiation Sterilization - A method for reducing microorganisms (sterilization) in a free-flowing product in a container. The product in the container is radiated with non-ionizing electromagnetic radiation at an energy density sufficient to achieve commercially sterile temperature and is manipulated in a manner to distribute heat and ensure that the product and the container reach a temperature sufficient to commercially sterilize the product and the interior surfaces of the container. | 2013-03-21 |
20130071528 | Raw Bone Product and Method - A raw bone product including ground raw bone compressed into a mass, wherein the ground raw bone has been subjected to a hydrostatic pressure of at least 4000 atm for a predetermined amount of time, and wherein the mass is maintained at a temperature of at most 40° F. | 2013-03-21 |
20130071529 | FROZEN PRODUCTS - A frozen composition is provided which includes hydrophobin. Also provided is the use of hydrophobin in inhibiting ice crystal growth and/or modifying ice crystal habit in frozen food products. | 2013-03-21 |
20130071530 | CASHEW NUT SHELL LIQUID HAVING IMPROVED STABILITY - The present invention provides a composition comprising one or more acids and a non-heated cashew nut shell liquid, wherein decarboxylation of an anacardic acid in the non-heated cashew nut is inhibited by the one or more acids. | 2013-03-21 |