12th week of 2020 patent applcation highlights part 8 |
Patent application number | Title | Published |
20200085653 | REMOVABLE POWER ASSIST FOR MANUAL WHEELCHAIR - Disclosed is a device for converting a manual wheelchair into an electronic wheelchair is provided. The device includes a joystick, a communication unit, a motor, a retractable friction roller, an engagement unit and a power source. The joystick is operably connected to a communication unit. The communication unit is operably connected to a motor. The motor includes an axle connected to a rotor. The retractable friction roller is mounted on the axle. The roller is placed in contact with a wheel of a manual wheelchair. The engagement unit is attached to the manual wheelchair to detachably attach the friction roller and the wheel. The power source is operably connected to the motor and the joystick. | 2020-03-19 |
20200085654 | MODULAR POWER BASES FOR WHEELCHAIRS - A modular power base for a wheelchair, the modular power base includes a leg module. The leg module includes an upper leg portion comprising a distal end and a proximal end. The proximal end is configured to be detachably and rotatably coupled to a seat portion of the wheelchair. The leg module also includes a lower leg portion having a first end and a second end, the first end of the lower leg portion being rotatably coupled to the distal end of the upper leg portion. The leg module also includes a first wheel rotatably coupled to the distal end of the upper leg portion and to the first end of the lower leg portion and a second wheel rotatably coupled to the second end of the lower leg portion. | 2020-03-19 |
20200085655 | Rotatable Swing Arm Stabilizer For Folding Wheelchairs - A swing arm assembly for a foldable wheelchair consisting of a camber tube and adapters is disclosed. The adapters mount to the frame of the wheelchair and receive the ends of the camber tube. One end of the camber tube is pinned into an adapter such that it pivots. The other end is pinned in an adapter using a quick release pin. The camber tube improves the stability of the foldable wheelchair. When desired to fold the wheelchair, the quick release pin is removed and the camber tube is rotated approximately 90 degrees, thereby allowing the wheelchair to fold. The adapters may be mounted to the wheelchair frame or to stub axles if used. The swing arm assembly adds substantial stiffness and stability to a folding wheelchair. | 2020-03-19 |
20200085656 | LIGHT WEIGHT SELF-CONTAINED ARTICULATING ASSEMBLY FOR BED FRAME MOUNTING - An articulating assembly for an adjustable bed has side supports received on side rails of a bed frame. A first axle extends between the side supports and a second axle extending between the side supports defining a fixed center section. An upper body support frame has a first torque tube concentrically received on the first axle. A thigh support frame has a second torque tube concentrically received on the second axle. A first actuator assembly supported in the center section is operably attached to rotate the first torque tube to articulate the upper body support frame over a range of positions from a horizontal unarticulated position to a fully articulated position. A second actuator assembly supported in the center section is operably attached to rotate the second torque tube to articulate the thigh support frame over a range of positions from a horizontal unarticulated position to a fully articulated position. | 2020-03-19 |
20200085657 | DETERMINING LIFTING EVENTS USING SENSORS FOR PERSON LIFTING APPARATUSES - A method of determining a lifting event of a person lifting apparatus is provided. The method includes receiving one or more of (i) current load information from a current measuring device that is indicative of current drawn by an actuator operatively connected to a lifting strap of the person lifting apparatus; (ii) strap position information from a position sensor that is indicative of a paid out length of the lifting strap of the person lifting apparatus; and (iii) weight information from a weight sensor that is indicative of a load supported by the lifting strap of the person lifting apparatus. A computing device comprising a processor using logic is used to identify at least one of a raising event, a repositioning event and a lowering event based on the one or more of the current load information, strap position information and weight information. | 2020-03-19 |
20200085658 | PATIENT LIFT SYSTEM - A patient lift system includes a motor and a drum. The drum is operably coupled to the motor. The drum can be selectively driven to rotate by the motor. A housing surrounds at least the motor and the drum. A load-bearing member is provided that includes a first end and a second end. The first end of the load-bearing member can be operably coupled to at least one of the housing and the drum. The second end of the load-bearing member can be operably coupled to a patient support assembly. An electrically conductive member can be positioned within the load-bearing member. A user interface is configured to actuate the patient support assembly in vertical and horizontal directions. | 2020-03-19 |
20200085659 | PERSON LIFTING APPARATUSES INCLUDING LIFTING STRAPS AND METHODS OF OPERATION BASED ON CURRENT DRAW - A person lifting apparatus includes a first lifting strap feeding device including a first drum and a first lifting strap wound on the first drum. A second lifting strap feeding device includes a second drum and a second lifting strap wound on the second drum. A controller is communicatively coupled to the first lifting strap feeding device and to the second lifting strap feeding device. The controller includes logic that controls operation of the first lifting strap feeding device and the second lifting strap feeding device based on a comparison of current draws of the first lifting strap feeding device and the second lifting strap feeding device. | 2020-03-19 |
20200085660 | MARINE RESCUE PATIENT ISOLATION APPARATUS - A patient isolation unit (PIU) for use in marine rescues. The PIU of this invention is useful to safely transport personnel exposed to, or potentially exposed to, an identified and/or known infectious agent or chemical warfare agent (CWA) on marine vessels and/or aircraft such as Coast Guard boasts, cutters and aircraft. The PIU has a generally tapered tubular shape compatible with wire rescue baskets conforming in shape to the human body and into which an injured, sick, or disabled person can be safely strapped, such as the Stokes litter rescue basket for hoisting and fit in rotary wing aircraft. | 2020-03-19 |
20200085661 | INTEGRATED DISSECTION BOARD TABLE LID - An anatomy table for use in autopsies and dissections comprises a base and an immersion storage tank arranged in the base. The anatomy table further comprises a dissection lid arranged on the base, wherein the dissection lid covers the immersion storage tank in its closed position. The table also comprises a hinge secured between the dissection lid and a top edge of the base, wherein the dissection lid rotates about the hinge between a first and second position, wherein the first position allows for access to the body stored in the anatomy table immersion storage tank while the second or closed position of the dissection lid allows for dissecting to occur directly on top of the anatomy table. This may allow for a two in one table to be arranged within a lab, such that autopsy work and dissection or cutting may be performed with the same piece of equipment, wherein two pieces of equipment are usually used within the lab for these procedures. | 2020-03-19 |
20200085662 | INTEGRATED OPERATING ROOM LIGHTING AND PATIENT WARMING SYSTEM - DESIGN AND COMPONENTS - An integrated and modular air and lighting plenum that is the primary directional lighting mounting apparatus and laminar flow diffuser of an HVAC system in a healthcare setting. The plenum provides laminar air flow from the ceiling to the room in which it is located in accordance with HVAC requirements for healthcare environment settings, by using a plurality of cylindrical airflow outlets. The use of cylindrical airflow outlets promotes laminar airflow by reducing sharp boundaries that induce turbulence (e.g., the corners of rectangular or square outlets) and creates a highly sterile environment around the patient and staff in the operating room. The surgical lights used in the integrated air and lighting plenum allow the beam direction, spot size, focal point, brightness, and color temperature of the emitted light to be controlled. | 2020-03-19 |
20200085663 | INTEGRATED OPERATING ROOM LIGHTING AND PATIENT WARMING SYSTEM - DESIGN AND COMPONENTS - A patient warming system for stabilizing and/or heating and cooling a patient includes a plurality of solid-surface sections arranged for attachment to a surgical table and a warming pad layer comprising a plurality of warming pads configured for removable connection to the plurality of solid-surface sections. At least one of the plurality of solid-surface sections includes a power connector for connection to an external power source. Each warming pad of the plurality of warming pads includes a foam insulation layer, a distributed heating element layer having a warming-pad power connection for connection to the power connector, an isothermal layer, and a flexible waterproof layer. Power supplied to the warming-pad power connection of the distributed heating element layer of the respective warming pad can be used to provide a user-selected uniform temperature over the surface of the flexible waterproof layer in order to prevent hot spots. | 2020-03-19 |
20200085664 | MEDICAL SUPPORT ARM WITH LOCKABLE PIVOT JOINT - A medical support arm may include a holding end, a coupling end, a coupling-end pivot joint for swiveling the support arm about a pivot axis (A | 2020-03-19 |
20200085665 | SPORTING APPARATUS FOR AUTOMATICALLY ADJUSTING THE CERVICAL VERTEBRAE - Provided is a sporting apparatus for automatically adjusting cervical vertebrae, which automatically moves while a user rests or sleeps with the apparatus, so as to ensure a user naturally maintains a good lying position. The sporting apparatus includes a rail assembly, a swing panel including a roller part inserted into the rail assembly to slidably move, and a support body which is coupled to and stably placed on an upper surface of the swing panel and on which a user's neck and head are stably placed. The apparatus makes an internal movement of an upper cervical vertebral portion to realign the cervical vertebrae, thereby inducing alignment and balance of the user's neck to be automatically achieved, and also inducing alignment and balance exercise of the head, a cervical vertebral portion, and an upper thoracic vertebral portion to be naturally conducted. | 2020-03-19 |
20200085666 | WALKING ASSISTANCE METHOD AND APPARATUS - A method and apparatus for assisting walking of a user is provided. Information related to a motion of a user wearing a walking assistance apparatus is measured by an inertial measurement unit (IMU), a gait phase of the user corresponding to the measured information is predicted using data learned in advance through machine learning, an assistance torque to be provided to the user is determined based on the predicted gait phase, and a driver is controlled to output the assistance torque. | 2020-03-19 |
20200085667 | HIP-KNEE PASSIVE EXOSKELETON DEVICE BASED ON CLUTCH TIME-SHARING CONTROL - The disclosure belongs to the technical field of lower limb exoskeleton, and specifically discloses a hip-knee passive exoskeleton device based on clutch time-sharing control, comprising a waist support subassembly, connection subassemblies, thigh subassemblies, clutch subassemblies, shank subassemblies and elastic member subassemblies, the waist support subassembly is configured to be connected to the waist, the connection subassemblies are configured to include two connection subassemblies which are arranged in bilateral symmetry on two sides of the support subassembly, the thigh subassemblies are configured to include two thigh subassemblies which are respectively connected to the two connection subassemblies, the clutch subassemblies are configured to include two clutch subassemblies which are respectively mounted on the two thigh subassemblies, the shank subassemblies are configured to include two shank subassemblies which are arranged in bilateral symmetry below the two thigh subassemblies, the elastic member subassemblies are configured to include two elastic member subassemblies which are arranged in bilateral symmetry. The disclosure can assist the movements of the knee and hip joints, thereby improving the energy utilization efficiency and reducing the metabolic energy consumption of walking. | 2020-03-19 |
20200085668 | ELECTRIC WALKING ASSISTIVE DEVICE FOR MULTIMODE WALKING TRAINING AND THE CONTROL METHOD THEREOF - The present invention provides a plurality of training modes for an electric walking rehabilitative device, including: constant speed mode, adaptive speed mode, strengthening push/pull mode, weight bearing mode, high frequency disturbance random speed mode, low frequency perturbation variable speed mode, direction control by handle push/pull forces mode, and slope mode, to improve the user's walking speed, muscle strength, balance, speed adjustment, direction control and slope walking. | 2020-03-19 |
20200085669 | FOAM GENERATOR FOR INVERTED COMPRESSION RECEPTACLES - The foam generator for inverted compression receptacles according to the present invention is configured such that liquid contents pumped by an internal pressure as a result of directly compressing an inverted compression receptacle ( | 2020-03-19 |
20200085670 | Soft Tissue Mobilization Instrument - A unitary manipulation instrument for use by a practitioner on soft tissue of a person formed of a pair of planar sections, each section including an outer tissue engaging surface. The sections are interconnected and each section is located in a different spatial plane such that the sections are oriented at 90 degrees one with respect to the other. | 2020-03-19 |
20200085671 | PHYSICAL OBSTRUCTION OF SCALP ARTERIAL CIRCULATION TO PREVENT CHEMOTHERAPY ASSOCIATED ALOPECIA - This document describes devices for mitigating or eliminating alopecia (hair loss) resulting from chemotherapy treatments and methods for their use. For example, this document describes headband devices that deliver localized pressure to portions of the patient's scalp to cause physical obstructions of scalp arterial circulation to mitigate alopecia. In some embodiments, localized pressure is exerted on frontal arteries, temporal arteries, and/or occipital arteries to reduce the blood flows therethrough. | 2020-03-19 |
20200085672 | DEVICES, SYSTEMS AND METHODS FOR MECHANICAL TISSUE STIMULATION - A system for mechanical stimulation of nasal tissues of a patient comprises a catheter assembly connected to a fluid flow generator. The catheter assembly comprises a generally oblong inflatable catheter defining at least one catheter volume and the catheter is configured to assume a shape suitable for insertion into a nasal cavity and to assume a shape suitable for stimulating a nasal tissue. The catheter assembly also comprises a tube part comprising at least one lumen configured to establish fluid flow connection between said fluid flow generator and catheter. Preferably, the catheter assembly comprises at least one vent for releasing fluid or permitting fluid to escape from the generated fluid flow. The fluid flow generator of previous aspects of the invention is configured to generate at least one of a smooth continuous flow, an oscillating flow and a pulsating flow. | 2020-03-19 |
20200085673 | METHOD AND SYSTEM FOR CUSTOMIZED OPERATION OF A THERAPEUTIC DEVICE - A therapeutic device includes sensors for collecting biometric health-related parameter information, such as a person's vital signs, during a therapy session for a particular user. A therapeutic program includes an artificial intelligence learning algorithm that uses the biometric health-related information for a particular user acquired during one or more training periods to customize therapeutic parameter values of a therapeutic program to deliver a specialized massage/therapy session that minimizes detriment, and maximizes benefit, to a user by comparing biometric health-related information collected during a therapy session to criteria that corresponds to the health-related information. Biometric health-related information may be stored to a database either local or remote relative to the therapeutic device. Users may retrieve biometric health-related information associated with therapy sessions and view graphical comparisons of changes to their vital signs and other collected data relative to changes in therapeutic parameter values as modified by the therapeutic program. | 2020-03-19 |
20200085674 | PRESSURE FIELD STIMULATION DEVICE HAVING ADAPTABLE ARM - Disclosed embodiments provide a pressure field stimulation device having an arm adaptable in shape. Embodiments of the improved stimulation device include a cup, a driver, and an arm. The arm is flexible in such a way that it holds its position when bent. The adaptable arm may be a handle, a member insertable into the vagina or rectum, or a connection member between the pressure field stimulator and another stimulator. In use, a user positions a rim of the cup such that an opening to the cavity is over an area to be stimulated (e.g., the clitoris). A sealed-, or substantially-sealed, chamber is formed by the cavity walls and the user's skin (surrounding the clitoris). A pressure field is generated in the chamber, providing sexual stimulation to the clitoris. The user can adjust the placement of the cup by bending the arm. | 2020-03-19 |
20200085675 | Versatile and Ergonomic Percussion Massage Appliance - A percussive massage appliance has a general Y-shape, with first and second handle portions being suitable for being held by first and second hands, respectively, of a user, with the percussive massage head reciprocating along an axis that lies in a major arc defined by the two handle portions. One use for the device is so that a user can grip the device with both hands while delivering a percussive massage to his own lower back muscles. The device has a rotation mechanism such that the user can rotate the reciprocation axis through an arc of about 120 degrees relative to the handles, and an extension handle mates with one of the handle portions, providing great versatility to the user. | 2020-03-19 |
20200085676 | PRESSURE FIELD STIMULATION DEVICE - Embodiments of the improved stimulation device include a cup and a driver. The cup has a cavity surrounded by a rim. The driver comprises a plate disposed on an underside of the cup, a cam disposed adjacent to the plate, and a motor mechanically coupled to the cam. The driver is configured to intermittently vary a volume of the cavity of the cup from a first volume to a second volume without returning the cup from the second volume to the first volume. In some embodiments, the cup returns from the second volume to the first volume, in between intermittent varying from the first volume to the second volume, due to the resilient nature of the material of the cup and/or the configuration of the cup. This varying of the volume between the first and second volumes creates a pressure field in a chamber formed by the cavity and a user's skin. | 2020-03-19 |
20200085677 | PRESSURE FIELD STIMULATION DEVICE - Disclosed embodiments provide an improved stimulation device. Embodiments of the improved stimulation device include a cup and a driver. The cup has a cavity surrounded by a rim. In use, a user positions the rim such that an opening to the cavity is over an area to be stimulated (for example, the clitoris). A sealed-, or substantially-sealed, chamber is formed by the cavity walls and the user's skin (surrounding the clitoris). A pressure field is generated in the chamber without generating a pressure below a reference pressure, which is gauge pressure reading of zero. In some embodiments, this is achieved by a driver configured to vary a volume of the cavity in such a way that the varied volume is not larger than an initial volume. In some embodiments, the stimulation device is a sex toy. In some embodiments, the stimulation device is a medical device. | 2020-03-19 |
20200085678 | PRESSURE FIELD STIMULATION DEVICE - Disclosed embodiments provide an improved stimulation device, including a cup and a driver. The cup has a cavity surrounded by a rim. In use, a user positions the rim such that an opening to the cavity is over an area to be stimulated (for example, the clitoris). A sealed- or substantially-sealed, chamber is formed by the cavity walls and the user's skin (surrounding the clitoris). A driver is configured to vary a volume of a cavity of a cup from a first volume to a second volume. The cup returns from the second volume to the first volume, in between intermittent varying from the first volume to the second volume, due to a buckle region wall of the cup springing out. The varying of the volume creates a pressure field in the chamber. The springing out produces a “thud” force, also used intechangably with “thump” force. | 2020-03-19 |
20200085679 | PRESSURE FIELD STIMULATOR HAVING A CUP INTEGRATED WITH A SHEATH - Embodiments of the invention relate to a pressure field stimulation device including a sheath having an integrated cup. The sheath and cup are together formed of (or consist of) a single piece of material. The pressure field stimulator has a cup and a driver, where the driver is configured to vary a volume of the cup. The pressure filed stimulator has a housing that has an opening therein with an edge on which a portion of the cup rests when installed. The sheath is tightly bound to the housing such that a driver can make contact with the cup. In some embodiments, the pressure field stimulator has a shaft portion, which may include a second stimulation device. The sheath can be bound over the shaft portion as well as the pressure field stimulator housing. | 2020-03-19 |
20200085680 | PERSONAL MASSAGER HAVING AN ARM ADAPTABLE IN SHAPE - An adjustable stimulation device is provided. Embodiments comprise a stimulator having a roller disposed adjacent a sheath. The roller presses the sheath against the G-spot or prostate of the user, providing stimulation. An arm having a first end is mechanically coupled to the shaft. A position of the stimulator and the arm with respect to one another is adjustable. The arm is flexible such that it holds its shape when bent. The shape of the arm is adjustable. The arm is adaptable into a plurality of shapes. In some embodiments, there is a handle or a second stimulator attached to a second end of the arm. | 2020-03-19 |
20200085681 | MASSAGER DEVICE WITH EXPANSION FUNCTION - Disclosed embodiments provide a massager having at least one expandable chamber. In some embodiments, there is provided an expandable shaft chamber that is inflatable to push a stimulator towards the G-spot of the user to increase contact pressure in that area. This inflation can also allow for a hands-free experience by expanding the width of the shaft inside the vagina for a snug fit tight against the vaginal or rectum walls. In some embodiments, there is provided an expandable ring chamber that is inflatable to securely hold a massager device inside the vagina or rectum, allowing for a hands-free experience. | 2020-03-19 |
20200085682 | PAD FOR PROVIDING A CARDIAC MASSAGE - Described herein is a pad for administering a cardiac massage, including: a first layer configured for being applied on the chest of a patient; and a second layer coupled to said first layer, the second layer being configured for receiving an action by an operator administering the cardiac massage, where said first layer is made of a material having an average value of the transmitted force, in an impact test at ambient conditions according to EN1621-1 at an energy of 10 J, lower than 25 kN. | 2020-03-19 |
20200085683 | HOT PLASMA DISEASE TREATMENT SYSTEM AND METHOD OF USE THEREOF - A hot plasma disease treatment system includes a mutually connected control system and at least one power supply system, the control system and the power supply system respectively being connected to and controlling a medium gas modulation system, at least one cooling system, at least one hot plasma generator, at least one plasma processing apparatus, a plasma treatment cabin, a detection feedback system, and a tail gas processing system, the medium gas modulation system being connected to the hot plasma generator, the cooling system being arranged on the hot plasma generator, the hot plasma generator and the plasma processing apparatus being connected, the plasma processing apparatus and the plasma treatment cabin being connected, and the plasma treatment cabin and the tail gas processing system being connected. | 2020-03-19 |
20200085684 | PORTABLE MASSAGE DEVICE - An improved portable massage device includes a first housing including a plurality of acupressure protrusions formed on an upper surface thereof and spaced apart from each other. The portable massage device further includes a battery supplying power, a motor connected to the battery to be turned on/off, and a rotating member mounted to surround the motor. In addition, the portable massage device includes a shield plate provided on the rotating member, at least one magnet detachably attached to the shield plate so that the shield plate vibrates when the motor rotates, a case accommodating the motor, a first switch connected to and controlling the battery to be turned on/off, and a second housing detachably combined with the first housing. The battery and the case are accommodated in the first housing or the second housing. | 2020-03-19 |
20200085685 | METHODS, SYSTEMS, AND COMPUTER PROGRAM PRODUCTS FOR MANAGING MULTIPLE DRUG PRODUCT PACKAGING SYSTEMS USING A COMMON DATABASE MANAGEMENT SYSTEM - A method includes performing, by a processor: providing a database that contains records corresponding to a plurality of drug product packaging systems, the records in the database being accessible through a common database management system, receiving a packaging order for at least one drug product, evaluating at least one criterion for fulfilling the packaging order, and identifying one of the plurality of drug product packaging systems to package the at least one drug product based on evaluating the at least one criterion. | 2020-03-19 |
20200085686 | MEDICATION BOTTLE WITH ANTI-TAMPERING FEATURES - A medication bottle includes an outer container wall, an inner container wall and a fluid, such as an aversive liquid, located between the walls. In another aspect, the fluid is located within separate compartments or channels located between the walls where the walls contact or are secured to each other. A further aspect provides a removeable cap including multiple sensors, at least one of which is a biometric sensor. | 2020-03-19 |
20200085687 | Storage Container - A storage device having a cylindrical housing with a first end, a second end and cylindrical side, wherein the ends are closed and the cylindrical side has one or more apertures. There is a cylindrical cover for each of the one or more apertures that slidably fit over the cylindrical side of the cylindrical housing and able to slide about the cylindrical side exposing or covering the one or more apertures. | 2020-03-19 |
20200085688 | PLASTIC CONTAINER PRODUCT - A plastic container product, in particular produced by a blow molding, filling and sealing method, comprising a container body ( | 2020-03-19 |
20200085689 | Aseptic Connectors with Integrated Wireless Connectivity - The present disclosure relates to aseptic connectors with integrated wireless connectivity. For example, an example system may include a removable clamp configured to secure a first portion of an aseptic connector to a second portion of the aseptic connector. The removable clamp may include a housing, a controller disposed within the housing, a rechargeable battery disposed within the housing, a wireless radio disposed within the housing, and a sensor plug receptacle configured to receive a sensor plug coupled to a sensor of the aseptic connector. The controller may be configured to determine a sensor output of the sensor and to transmit the output using the wireless radio. | 2020-03-19 |
20200085690 | MEDICAL CONNECTORS CONFIGURED TO RECEIVE EMITTERS OF THERAPEUTIC AGENTS - In some embodiments, a medical fluid connector is configured to receive an emitter of therapeutic agents to be emitted into a fluid pathway within the connector, the medical fluid connector comprising a proximal female end, an intermediate region, a distal male end, and a fluid pathway extending from the proximal female end, through the intermediate region, to the distal male end. A retaining structure is positioned within the intermediate region. The retaining structure is configured to securely receive an emitter of one or more therapeutic agents in a position and orientation where the fluid pathway is configured to convey fluid moving longitudinally through the fluid pathway directly into a proximal region of the emitter, around one or more lateral surfaces of the emitter, and toward the distal male end. | 2020-03-19 |
20200085691 | SYSTEM AND METHOD FOR COMPOUNDING MEDICATION - A medication compounding system is described that is capable of receiving one or more medications and diluents and that includes an array of moveable transfer cartridges to access a medication container and to transfer medication. The transferred medication may be joined with a diluent to form a compounded medication. The resulting compounded medication may then be directed to a filling port where a compounded medication container may be coupled. A second medication container may align with a second transfer cartridge to transfer a second medication. Because the device may comprise one or more medications and diluents, a series of compounded medications may be created using an individual transfer cartridge for each medication. | 2020-03-19 |
20200085692 | MEDICATION COMMINUTION AND DELIVERY CUP - A single-use nesting cup for use with mechanical comminution devices having a spinning drive mechanism for pulverizing pills into powder is disclosed. Each cup has a textured base surface that provides for a more efficient grinding and crushing of pills inserted between two such cups when an upper cup is spinningly brought to bear down on a bottom cup. The textured surface of each cup base has a symmetric three-dimensional wave design with each wave arcing along a curve from an outer cylindrical wall of the cup spiraling in toward a center point of the base of each cup. The crest and troughs of each wave act as grinding edges while the overall symmetric wave design acts to maintain the one or more pills and it's powdered form in the center of the bottom cup. | 2020-03-19 |
20200085693 | METHOD AND APPARATUS FOR PRECISE MEASUREMENT AND DISPENSING OF LIQUIDS - A dispenser device for dispensing fluids is described. The dispenser can include a reservoir cap that can directly attach to and replace the screw top cap of traditional screw top bottle. The reservoir cap includes an air reservoir that can facilitate movement of the fluid through the device. The reservoir cap is coupled to a dispenser that is configured to receive the fluid from the cap. The dispenser can be detached from the cap and used to directly dispense the fluid. | 2020-03-19 |
20200085694 | SYSTEM AND METHOD FOR STORING MEDICATION AND ALERTING USERS AND CAREGIVERS FOR TIMELY INTAKE - A computerized pill intake reminder device is disclosed. The computerized pill intake reminder device is used for storing pills, detecting the number of pills in each pouch of the blister pack, inventory management, reminding users to take their medication on time, alerting by providing an audible or a visual alarm if the medications are not taken on time and as a secondary mechanism alerting their caregiver if the user has not responded to the alert and taken the medication on time. | 2020-03-19 |
20200085695 | CONNECTORS FOR INFUSION PUMP FEEDING SETS - Improved feeding set connectors and cassettes are disclosed for use with peristaltic infusion pumps for safely delivering enteral nutritional fluids to a patient. The connectors provide an easy to use “pump-to-set” integration or “keying” system for specific reusable infusion pumps and their matching feeding sets, and can be utilized by medical professionals having various skill levels. The inventive feeding set cassettes can prevent accidental free flow of enteral fluids into a patient, even upon inadvertent release of the connector from the pumping mechanism. | 2020-03-19 |
20200085696 | FEEDING SET AND ENTERAL FEEDING PUMP - A feeding set for use with a peristaltic enteral feeding pump to deliver nutritional liquid fluid to a patient includes a container having nutritional liquid. A conduit assembly includes tubing placeable in fluid communication with the container and adapted for mounting on the enteral feeding pump. The tubing provides a fluid pathway for delivering the nutritional liquid from the container to a patient when the tubing is mounted on the enteral feeding pump. An identification member is mounted on the conduit assembly and has at least one characteristic of a nutritional liquid associated with the feeding set represented by the identification member. The identification member is positioned on the conduit assembly so as to permit automatic identification by the enteral feeding pump of the at least one characteristic of the nutritional liquid upon mounting the conduit assembly on the enteral feeding pump. | 2020-03-19 |
20200085697 | DENTAL COMPOSITION - The present invention relates to a dental composition comprising a specific radically polymerizable compound and a radical initiator system. Furthermore, the present invention relates to the specific radically polymerizable compound and its use in a dental composition. The specific radically polymerizable compound of the present invention has an allyl (meth)acrylamide group and a phosphoric acid ester group. | 2020-03-19 |
20200085698 | COMPOSITIONS WITH DOPED TITANIUM DIOXIDE NANOPARTICLES AND METHODS OF USE - A dental composition comprising doped T1O2 nanoparticles, and a curable resin material, wherein the curable resin material comprises a polymer precursor component, and wherein the dopant may be one or more of, for example, N (nitrogen), Ag (silver), F (fluorine), P (phosphorus), and P04 (phosphate). A method of using the dental composition in a dental application. The dental composition may be antibacterial in the absence of visible light or UV light. | 2020-03-19 |
20200085699 | A METHOD FOR MANUFACTURING COLORED SHEET AND COLORED SHEET - A method for manufacturing a colored sheet for coloring an object by adhesion to the object includes, a coloring step of applying by spraying, a first coating fluid containing first microparticles for coloring to a thin film of a print receiver body which has a sheet-shaped support body and the thin film, the thin film being peelably held on the sheet-shaped support body to serve as a base material of an adhesive sheet which is to be adhered to the object, and a restricting step of applying by spraying, before the coloring step, a second coating fluid for restricting the first microparticles from penetrating the thin film to a location where the first coating fluid is to be applied. | 2020-03-19 |
20200085700 | SOLVENT MODIFICATIONS TO PREMOISTENED SUBSTRATES - Formulations suitable for use with fibrous substrates are provided. The formulations provide increased wet strength, high dispersibility, and shape retention of premoistened fibrous substrates. Such formulations comprise at least one dielectric-adjusting solvent, and optionally water, coupling agents, salts, personal care components, hard surface cleaning components, or combinations thereof. | 2020-03-19 |
20200085701 | COMPOSITION IN THE FORM OF A DIRECT EMULSION COMPRISING A SILICONE RESIN AND A NON-VOLATILE SILICONE OIL, AND PROCESS USING THE SAME - The present invention relates to a cosmetic composition in the form of an oil-in-water emulsion, comprising: ⋅water; ⋅at least 10% by weight, relative to the weight of the composition, of at least one silicone resin; ⋅at least one non-volatile silicone oil, not comprising any nitrogen atoms, or any —Si—H groups, or any (poly)oxyalkylene groups, the oxyalkylene unit being C | 2020-03-19 |
20200085702 | OIL-IN-WATER EMULSION COMPRISING A SPECIFIC SURFACTANT SYSTEM - The invention relates to a cosmetic composition in the form of an oil-in-water emulsion comprising: (i) at least one lipophilic surfactant with HLB less than or equal to 9, and (ii) at least one specific anionic surfactant comprising at least one sulfate and/or sulfonate function; said composition comprising from 0% to 8% by weight of additional surfactant(s) relative to the total weight of the composition. It also relates to the associated cosmetic process. | 2020-03-19 |
20200085703 | HAIR CARE PRODUCTS WITH SPECIAL RENEWABLE RAW MATERIALS - Hair treatment products are provided in the form of two-phase systems with two separate, visually discernible continuous phases with a common vertical phase boundary, containing one water phase (I) and one oil phase (II),
| 2020-03-19 |
20200085704 | TRANSFER DEVICE FOR MAKING UP KERATIN MATERIALS - The present invention relates to a process for manufacturing a device for applying a cosmetic product by transfer onto human keratin materials, comprising the step consisting in printing, using at least one digital printer, onto a surface a cosmetic ink, the ink being in the form of an oil-in-water or water-in-oil emulsion comprising an emulsifier, the ink being liquid at 20° C. | 2020-03-19 |
20200085705 | Method of Encapsulating Compounds - The present invention relates to a method of encapsulating an uncharged, soluble, active compound within a self-assembled ionomer complex formed from polyelectrolytes, wherein the said method comprises the steps of mixing a solution comprising at least one polycation and polyanion with active compound, or adding a polyion to a solution comprising an oppositely charged polyion coupled to the active compound, wherein the interaction between the active compound and ionomer complex is non-ionic and non-covalent in nature. The invention also relates to an ionomer complex prepared thereform for use in transport and delivery of the compounds. In a preferred embodiment, the ionomer complex comprises poly-L-arginine, Poly(ethylene oxide)-b-poly(acrylic acid) (PAA-b-PEO), wherein the said ionomer encapsulates 4-methoxyphenyl β-D-glucopyranoside (MG). | 2020-03-19 |
20200085706 | SKIN IMPROVING KIT AND FACE PACK - A skin improving kit includes a water retentive sheet; and an air-tightly sealed container that is filled with the hydrogen water. A face pack includes a water retentive sheet that has a face shape; and hydrogen water with which at least a surface of the water retentive sheet which comes into contact with a face has been impregnated. | 2020-03-19 |
20200085707 | Oral Care Compositions Including Charcoal - An oral care composition including a dentifrice and a film suspended in the dentifrice, wherein the film includes charcoal. | 2020-03-19 |
20200085708 | OXIDIZING COMPOSITION FOR TREATING KERATIN FIBRES, COMPRISING A SCLEROGLUCAN GUM AND A PHOSPHORUS-BASED SEQUESTRANT - The present invention relates to a cosmetic composition for treating keratin fibres, preferably human keratin fibres such as the hair, comprising, in a cosmetically acceptable medium: —one or more chemical oxidizing agents, —one or more scleroglucan gums, —one or more phosphorus-based sequestrants. The present invention also relates to a process for treating keratin fibres, preferably human keratin fibres such as the hair, comprising the application of the composition to the keratin fibres. The process according to the invention is preferably a process for bleaching, dyeing or permanently reshaping keratin fibres. | 2020-03-19 |
20200085709 | ANHYDROUS SOLID COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A METABISULFITE - The present invention relates to an anhydrous solid composition for dyeing keratin fibres, in particular human keratin fibres such as the hair, comprising one or more metabisulfites. The present invention also relates to a packaging article containing said composition. The present invention also relates to processes for dyeing keratin fibres using said composition or said packaging article. Finally, the present invention also relates to the use of said composition or of said packaging article for dyeing keratin fibres, and in particular human keratin fibres such as the hair. | 2020-03-19 |
20200085710 | OILY MOISTURIZER AND TOPICAL SKIN COMPOSITION CONTAINING SAME - This oily moisturizer is composed of either an esterified product of a component A that is ditrimethylolpropane, and a component B that is one fatty acid, or two or more fatty acids, selected from among saturated fatty acids of 6 to 12 carbon atoms, or an esterified product of the component A, the component B, and a component C that is one fatty acid, or two or more fatty acids, selected from among fatty acids of 13 to 28 carbon atoms, wherein the hydroxyl value of the esterified product is not more than 140 mgKOH/g, and the mass ratio between fatty acid residues derived from the component B and fatty acid residues derived from the component C within the fatty acid residues that constitute the esterified product of the component A, the component B and the component C is within a range from 99.9:0.1 to 60:40. | 2020-03-19 |
20200085711 | IMPROVED LACTAM SOLUBILITY - Compositions comprising a lactam and an alkyl lactate. The compositions are suitable for use as anti-microbial, anti-biofilm and bacteriostatic compositions. | 2020-03-19 |
20200085712 | COMPOSITION - Provided is a composition containing the following components (A), (B) and (C) and suppressing formation of scum during cleansing, wherein a weight ratio of (A)/(B) is 0.2-5 and a weight ratio of ((A)+(B))/(C) is 0.01-10:
| 2020-03-19 |
20200085713 | LIQUID PERSONAL CLEANSING COMPOSITION - The invention relates to aqueous skin cleansing compositions. Specific amounts and chain length of acyl glycinate and acyl glutamate when used in specified ratios, have been found to unexpectedly enhance lather volume and texture, as well as provide superior mildness. | 2020-03-19 |
20200085714 | Process for Dyeing and Relaxing Curls of Keratin Fibres, Using Reducing Agents and Hair Dyes, and Associated Kit - The present invention relates to a process for dyeing and relaxing curls of keratin fibres, such as the hair, which comprises the application to the fibres of one or more acidic compositions comprising reducing agents and of one or more compositions comprising hair-dyeing agents, and a step of heat treatment of the fibres by means of a heating tool. A subject of the invention is also the use of the composition(s) comprising reducing agents and of the composition(s) comprising hair-dyeing agents in a process for dyeing and relaxing curls of keratin fibres. Finally, a subject of the invention is a multi-compartment device or “kit” suitable for carrying out such a process. | 2020-03-19 |
20200085715 | RELATING TO ORGANIC COMPOUNDS - A cosmetic ingredient comprising crenatoside and acteoside when applied to the skin is useful to provide cosmetic and perfumery benefits. | 2020-03-19 |
20200085716 | USE OF SPECIFIC POLYMERS TO BRING ABOUT AN ANTI-POLLUTION EFFECT - The present invention relates to the use of a polymer or of a cosmetic product comprising said polymer, and additionally other known cosmetic ingredients, to bring about an anti-pollution effect on human skin or on human hair, especially to protect human skin or human hair from dust, wherein the polymer is a cationic, anionic or non-ionic polymer, and wherein the polymer has a solubility in water of at least 0.01 g of polymer in 100 g of water at 20° C. at least at a pH in the range between 4 and 9. | 2020-03-19 |
20200085717 | MILD OPTICALLY STABLE SURFACTANT COMPOSITIONS - Provided are mild, optically stable, low pH surfactant compositions comprising low molecular weight, non-crosslinked, linear acrylic emulsion copolymers and their use as ocular and/or dermal irritation mitigants in such compositions. The disclosed polymers have a number average molecular wt. of 100,000 Daltons or less, the polymer comprises at least 51 wt. % of polymerized residues of at least one ethylenically unsaturated C | 2020-03-19 |
20200085718 | COMPOSITIONS AND KITS FOR THE REMOVAL OF IRRITATING COMPOUNDS FROM BODILY SURFACES - The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble. | 2020-03-19 |
20200085719 | COSMETIC COMPOSITION COMPRISING WATER, A SILICONE RESIN AND A NON-VOLATILE SILICONE OIL, AND PROCESS USING THE SAME - The present invention relates to a cosmetic composition comprising: at least 10% by weight, relative to the weight of the composition, of water; •at least 10% by weight, relative to the weight of the composition, of at least one silicone resin; •at least one non-volatile silicone oil, not comprising any nitrogen atoms, or any —Si—H groups, or any (poly)oxyalkylene groups, the oxyalkylene unit being C | 2020-03-19 |
20200085720 | COMPOSITION AND METHOD OF PREPARATION - A composition comprises (A) a silicone elastomer. The (A) silicone elastomer comprises the reaction product of: (a) an organohydrogensiloxane having an average of at least two silicon-bonded hydrogen atoms per molecule; (b) a crosslinking agent having an average of at least two ethylenically unsaturated groups per molecule; and (c) a hydrosilylation catalyst. The reaction product is formed in the in the presence of (d) a silicone polyether polymer; and (e) particles. The composition further comprises (B) a carrier fluid. The (e) particles are dispersed in the (A) silicone elastomer in the composition. A method of preparing the composition is also disclosed. | 2020-03-19 |
20200085721 | COSMETIC PRODUCT - A thickened composition for a cosmetic product including a content that is taken through a mesh contains a fine particulate powder and a silicone crosspolymer having a structure where dimethicone is cross-linked with an organic group, and has a storage modulus G′≥3000 Pa, as measured with a rheometer under the conditions of a gap of 0.5 mm, a strain oscillation angle of 0.1%, a frequency of 1 Hz, and a temperature of 25° C. while increasing stress applied with a 25 mm φ cone plate, and a loss tangent tan δ≤0.2, as calculated as a loss modulus G″ measured under the same conditions divided by the storage modulus G′. A cosmetic product includes a container including an inner lid with a tight mesh and an outer lid for tightly closing a container body, and the thickened composition contained in the container body under the inner lid. | 2020-03-19 |
20200085722 | COMPACT POWDER FREE OF SURFACE-TREATED TALC, BASED ON MICA, A NON-VOLATILE, NON-PHENYL SILICONE OIL AND AN AMORPHOUS HYDROCARBON-BASED BLOCK COPOLYMER - The present invention thus relates to a solid composition, especially for coating keratin materials, more particularly for making up and/or caring for keratin materials such as the skin, in compact powder form, especially comprising a physiologically acceptable medium and containing at least: —an oily phase in an amount of at least 20% by weight relative to the total weight of the composition; said oily phase comprising at least one non-volatile non-phenyl silicone oil; and —a pulverulent phase in an amount of at least 40% by weight relative to the total weight of the composition; said pulverulent phase comprising at least mica particles; and —at least one amorphous hydrocarbon-based block copolymer; said composition not containing any talc particles that have not been surface-treated and being able to be obtained via a process comprising the following steps: (i) the oily phase, the amorphous hydrocarbon-based block copolymer, the pulverulent phase and the volatile solvent(s) are mixed to form a slurry; and (ii) the slurry is formed in a container by compacting, in particular pressing and/or suction, to obtain the composition in powder form. The invention also relates to a process for coating keratin materials, more particularly for making up and/or caring for keratin materials such as the skin, characterized in that it comprises the application to the keratin materials of a composition as defined previously. | 2020-03-19 |
20200085723 | COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID beta,beta-DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL - The present invention relates to a composition, especially comprising a physiologically acceptable medium, especially for coating keratin materials, more particularly for making up and/or caring for keratin materials such as the skin, a) an oily continuous phase, and b) at least one mixture of liquid organic UV-screening agents comprising: (i) at least one UV-screening agent of the β,β-diphenylacrylate type, and (ii) at least one UV-screening agent of the salicylate type; and c) at least one non-cyclic volatile silicone oil; and d) at least one pigment. The invention also relates to a process for coating keratin materials, more particularly for making up and/or caring for keratin materials, such as the skin, characterized in that it comprises the application to the keratin materials of a composition as defined previously. | 2020-03-19 |
20200085724 | Sunscreen Compositions With Natural Waxes For Improved Water Resistance - A sunscreen composition having improved water resistance comprising (i) a sunscreen active agent; (ii) a water resistant agent comprising a natural wax having a Damping Factor of less than 1.0 in a linear viscoelastic range at body temperature; and (iii) an emulsifier or a surfactant capable of stabilizing an emulsion of components (i) to (iii), wherein said sunscreen composition maintains at least 75%, preferably at least 85%, and most preferably at least 99%, of its static SPF after water immersion for 4 hours. | 2020-03-19 |
20200085725 | Antibacterial Formulations and Methods of Use - Provided herein are antibacterial and antioxidant oral care formulations. Generally, the oral care formulations contain vinegar, at least one natural extract and sodium bicarbonate in water. Also provided are the antibacterial mouthwash, toothpaste, chewing gum and breath freshener formulations. | 2020-03-19 |
20200085726 | PLANT EXTRACTS TO REDUCE THE APPEARANCE OF HYPERPIGMENTED SKIN OR TO LIGHTEN SKIN - A method for reducing the appearance of hyperpigmented skin is disclosed. The method can include topically applying to hyperpigmented skin of a person a composition that includes at least one of, at least two of, or all three of (i) an effective amount of | 2020-03-19 |
20200085727 | MEANS AND METHODS FOR PREVENTING AND/OR TREATING CARIES - The present invention relates to a microorganism belonging to the group of lactic acid bacteria characterized in that it is capable of specifically binding to | 2020-03-19 |
20200085728 | Antipsychotic Injectable Depot Composition - The present invention is directed to a composition that can be used to deliver an antipsychotic drug such as risperidone, paliperidone or a combination thereof, as an injectable in-situ forming biodegradable implant for extended release providing therapeutic plasma levels from the first day. The composition is in the form of drug suspension on a biodegradable and biocompatible copolymer or copolymers solution using water miscible solvents that is administered in liquid form. Once the composition contacts the body fluids, the polymer matrix hardens retaining the drug, forming a solid or semisolid implant that releases the drug in a continuous manner. Therapeutic plasma levels of the drug can be achieved from the first day up to at least 14 days or more even up to at least four weeks. | 2020-03-19 |
20200085729 | PHARMACEUTICAL SOLUTION FORMULATIONS FOR PRESSURISED METERED DOSE INHALERS - The invention relates to the prevention and/or treatment of a severe broncho-pulmonary disease by administering a solution formulation from a pressurized metered dose inhaler capable of providing therapeutical doses of two or more active drug substances to the lung, wherein all the active drug substances are fully dissolved in the formulation as well as the two or more active drug substances are delivered with substantially the same particle size distribution. | 2020-03-19 |
20200085730 | 3D NAVIGATION OF NANOPARTICLES VIA INDUCTION OF METASTABLE DIAMAGNETIC RESPONSE - Methods and devices for three-dimensional navigation of magnetic nanoparticles are provided. A method can comprise introducing high-anisotropy magnetic nanoparticles to a mammal and directing the high-anisotropy magnetic nanoparticles towards a target region of the mammal. Direction control is achieved by subjecting the high-anisotropy magnetic nanoparticles to an alternating signal comprising a uniform magnetic field pulse having a strength greater than a coercivity of the high-anisotropy magnetic nanoparticles and a magnetic gradient pulse having a highest strength that is less than the coercivity of the high-anisotropy magnetic nanoparticles and a location of a lowest strength at the target region of the mammal, and the direction of the uniform magnetic field pulse being in an opposite direction of the magnetic gradient pulse. | 2020-03-19 |
20200085731 | STABLE LIQUID FORMULATIONS OF MELPHALAN - The present invention relates to stable, liquid parenteral formulations of Melphalan or pharmaceutically acceptable salts thereof. Further this invention also describes process of preparing such formulations. | 2020-03-19 |
20200085732 | Prolonged Release of Local Anesthetics Using Microparticles and Surgery Applications - Methods and compositions for providing long term pain relief in, for example, surgery recovery, including injecting a composition comprising a plurality of microparticles having different sizes and at least one local anesthetic loaded into the microparticles at different loading levels. Extended prolonged blockage of nerve action in sheep testing was confirmed. Some of the microparticles comprise a high loading of local anesthetic. Testing in sheep showed nerve blockage for at least six days. | 2020-03-19 |
20200085733 | HYPOTONIC HYDROGEL FORMULATIONS FOR ENHANCED TRANSPORT OF ACTIVE AGENTS AT MUCOSAL SURFACES - Hypotonic formulations of hydrogel forming polymers, preferably poloxamers, have been developed for enhanced delivery through mucosa of therapeutic, diagnostic, prophylactic or other agents, to epithelial tissues, especially those having a mucosal coating. The polymers are administered at a concentration above, at or less than their critical gelling concentration (CGC) under isotonic conditions. The hypotonicity of the formulation is adjusted so that the polymer gels at the lower concentration. A Poloxamer gel administered into the vagina or colorectum at its CGC will form a “plug” of gel in the lumen. | 2020-03-19 |
20200085734 | PHARMACEUTICAL DOSAGE FORMS CONTAINING TASK-I AND TASK-3 CHANNEL INHIBITORS, AND THE USE OF SAME IN BREATHING DISORDER THERAPY - The invention relates to new pharmaceutical dosage forms containing potent and selective TASK-1 and/or TASK-3 channel inhibitors, and the use of same to treat and/or prevent breathing disorders including sleep-related breathing disorders such as obstructive and central sleep apnoea and snoring. | 2020-03-19 |
20200085735 | Novel methods for delivering therapeutics agents to the eye via the nasal passages - The invention is directed to delivering therapeutic agents to the eye for the purpose of treating ophthalmic disorders, diseases and injuries. In particular, the invention is directed to delivering therapeutic agents to the eye for the purpose of treating ophthalmic disorders, diseases and injuries by targeted intranasal administration of the therapeutic agents. The invention is specifically directed to treating disorders, diseases and injuries of the cornea and ocular surface, treating retinal disorders, diseases and injuries and optic nerve disorders, diseases and injuries by targeted intranasal administration of the therapeutic agents. | 2020-03-19 |
20200085736 | RESIDENCE STRUCTURES AND RELATED METHODS - Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.g., ingestion of a solution that induces rapid dissolution/degradation). In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance (e.g., a therapeutic agent), and, optionally, a linker. In some such embodiments, the linker may be configured to degrade such that the residence structure breaks apart and is released from the location internally of the subject after a predetermined amount of time. | 2020-03-19 |
20200085737 | RESIDENCE STRUCTURES AND RELATED METHODS - Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.g., ingestion of a solution that induces rapid dissolution/degradation). In certain embodiments, the structure has a modular design, combining a material configured for controlled release of therapeutic, diagnostic, and/or enhancement agents with a structural material necessary for gastric residence but configured for controlled and/or tunable degradation/dissolution to determine the time at which retention shape integrity is lost and the structure passes out of the gastric cavity. For example, in certain embodiments, the residence structure comprises a first elastic component, a second component configured to release an active substance (e.g., a therapeutic agent), and, optionally, a linker. In some such embodiments, the linker may be configured to degrade such that the residence structure breaks apart and is released from the location internally of the subject after a predetermined amount of time. | 2020-03-19 |
20200085738 | AVIAN TINCTURE - An avian tincture composition and associated methods for producing the same for treatment of the avian species with the avian tincture. The avian tincture may be used in the treatment of abscesses, inflamed and swollen leg joints, respiratory issues, wounds, infection, and acute disease or parasite overload conditions. | 2020-03-19 |
20200085739 | VETERINARY CANNABINOID, MENTHOL AND ANESTHETIC COMPOSITIONS AND METHODS - The present disclosure relates to compositions, including, hydrogel compositions useful as analgesics including cannabinoids, menthol and anesthetic in a composition formulated to be administrable to a non-human animal rectally as a suppository. | 2020-03-19 |
20200085740 | WATER-SOLUBLE, POWDERED CANNABINOID AND/OR TERPENE EXTRACT - The invention relates to the preparation of a water soluble, powdered pharmaceutically active cannabinoid and/or terpene extract from plant materials, a powder where the bulk density can easily be modified depending on the final dosage form required. The extract is first treated with a solvent to solubilize the cannabinoids, then combined with an emulsifier. The solubilized mixture is then dried to evaporate the solvent, leaving the water-soluble cannabinoid extract powder. The resulting powder remaining stable at room temperature for at least one year and can be compounded into various pharmaceutical powdered formulations, with varying bulk powder densities. | 2020-03-19 |
20200085741 | PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE OF WEAK ACID DRUGS AND USES THEREOF - Provided herein are pharmaceutical compositions containing at least one liposome, said liposome comprise an external lipid bilayer including at least one vesicle-forming phospholipid and less than 15 mole % of sterol; and an internal aqueous medium including a weak acid drug and weak acid salt. The pharmaceutical compositions reduce the burst release of the weak acid drug. Also provided is the use of the pharmaceutical composition disclosed herein to treat respiratory diseases and reduce the side effect of the weak acid drug. | 2020-03-19 |
20200085742 | NANOSCALE CARRIERS FOR THE DELIVERY OR CO-DELIVERY OF CHEMOTHERAPEUTICS, NUCLEIC ACIDS AND PHOTOSENSITIZERS - Nanoscale coordination polymer nanoparticles for the co-delivery of multiple therapeutic agents are described. The multiple therapeutic agents can include a combination of different chemotherapeutic agents, a combination of one or more chemotherapeutic agents and one or more nucleic acids, such as small interfering RNA (siRNA) or microRNA, a combination of one or more chemotherapeutic agents and a photosensitizer (i.e., for use in photodynamic therapy), or a plurality of different siRNAs. Pharmaceutical formulations including the nanoparticles, methods of using the nanoparticles to treat cancer, and methods of making the nanoparticles are also described. | 2020-03-19 |
20200085743 | GLUCOSE SENSITIVE COMPOSITIONS FOR DRUG DELIVERY - Disclosed herein are glucose-sensitive drug delivery systems including polymeric shell encapsulating an active agent. Upon exposure to a sufficient concentration of glucose, the shell is ruptured, releasing the active agent for absorption. | 2020-03-19 |
20200085744 | METHOD FOR PREPARING A STABLE CONTROLLED-RELEASE PROPOLIS COLLOIDAL DISPERSION SYSTEM FOR VARIOUS USES - Method for preparing a stable controlled-release propolis colloidal dispersion system, wherein propolis is micronized and then dispersed in the solvent system, which is under stirring and consists of deionized water and either natural 1,3-propanediol or glycerol, in which deionized water hydroxypropyl-β-cyclodextrin or β-cyclodextrin has been predissolved, and as the propolis/cyclodextrin/solvents system is under intense stirring for 30-45 min, a liposomal suspension is added thereto, and stirring is performed for 1 to 4 hours under continuous measurement of the total content in polyphenols and of the encapsulation efficiency %, until the specific parameters reach the desired values so that the stirring process is ended and the colloidal system is filtrated through suitable filters, its pH is adjusted and the size of dispersed particles as well as the release rate of the polyphenols of propolis in a buffer solution at pH 7.2 and 37° C. are measured and the colloidal system is stored. | 2020-03-19 |
20200085745 | PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES - The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a solution of pre-formed lipid nanoparticles and mRNA at a low concentration. | 2020-03-19 |
20200085746 | MANNITOL GRANULES FOR DIRECT COMPRESSION - The present invention relates to mannitol granules that are of use for the preparation of tablets by direct compression, which do not require a small amount of lubricant in order to be processed. The present invention also relates to a process for preparing such granules. The present invention also encompasses pulverulent compositions comprising these granules, and also direct compression processes using these pulverulent compositions. Finally, the present invention relates to tablets composed of these pulverulent compositions. | 2020-03-19 |
20200085747 | A NOVEL METHOD FOR BLOOD PLASMA PROTEIN ACTIVITY PRESERVATION - A method for blood plasma protein activity preservation is provided. The method comprises the steps of mixing blood plasma with two or more protectants selected from the group consisting of triglyceride, glycerol, propylene glycol, alanine, serine, glycine, alginate, and sucrose to obtain a mixture; and lyophilizing the mixture. | 2020-03-19 |
20200085748 | FORMULATIONS OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE - The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders. | 2020-03-19 |
20200085749 | IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS - The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation. | 2020-03-19 |
20200085750 | FORMULATIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID - A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a disintegrant, a surfactant, a binder, and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Processes of preparing pharmaceutical compositions comprising Compound 1 are also disclosed. | 2020-03-19 |
20200085751 | NOVEL AMORPHOUS DISPERSION OF 4-METHYL-3-QUINOLIN-3-YLETHYNYL-BENZOIC ACID N'-(2-CHLORO-6-METHYL-BENZOYL) HYDRAZIDE - An oral solid dosage form comprising a mixture of compound of formula I and a fusible polymeric carrier; and optionally pharmaceutically acceptable excipients, wherein the mixture is an amorphous dispersion. | 2020-03-19 |
20200085753 | MICROPARTICLES, METHODS FOR THEIR PREPARATION AND USE - The invention relates to microparticles comprising a crosslinked gel and methods for making and using same. | 2020-03-19 |