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10th week of 2011 patent applcation highlights part 37
Patent application numberTitlePublished
20110059800PRESENTING AND CONTROLLING WAGERING GAME INFORMATION - A network browser and wagering game toolbar (“toolbar”) are described herein. The network browser has a main display area that can display content. The toolbar can be in, or a part of, the network browser. The network browser and the toolbar can receive and display content. Specifically, the toolbar can receive and display wagering game content from a wagering game network as the main display area can receive and display content originating outside the wagering game network. In some embodiments, the toolbar can present content originating from one or more wagering game player accounts that provide audience participation in, or related to, wagering game activity presented on the toolbar.2011-03-10
20110059801NETWORK GAME SYSTEM, NETWORK GAME SYSTEM CONTROL METHOD, GAME CONTROL DEVICE, AND INFORMATION STORAGE MEDIUM - A first game character control section controls the action of a first game character which is an operation target for a user, based on an operation carried out by the user. A second game character control section controls the action of one or more second game characters, based on the action control data. In a case where a chat message is input in any game device, addressed to one or more users of one or more other game devices, an action control data changing section changes the action control data, based on the chat message.2011-03-10
20110059802Constant Velocity Joint - A constant velocity joint is disclosed that includes a first rotatable shaft, the first shaft comprising an axle portion having on one end an enlarged pocket portion, the pocket portion having a plurality of circumferentially and radially spaced ball pockets and a distal end; a corresponding plurality of spherical balls disposed in the pockets; and a second rotatable shaft comprising a joint housing, the joint housing having a central bore with a corresponding plurality of axially extending, circumferentially and radially spaced ball grooves disposed about the second longitudinal axis and a base, the joint housing disposed over the pocket portion with the corresponding plurality of balls disposed in the grooves, the joint providing a range of angular and axial movement of the first shaft relative to the second shaft, the distal end of the pocket portion having a convex surface configured to provide a predetermined a range of angular movement.2011-03-10
20110059803Constant Velocity Joint - A boot assembly and constant velocity joint utilizing the boot assembly is provided. The constant velocity joint and boot assembly includes a first shaft, the first shaft having an axle portion extending between a first end and a second end, at least one of the first end and the second end having an enlarged joint portion. It also includes a hollow boot disposed on the first shaft having a joint end and a shaft end, the joint end disposed proximate the enlarged joint portion and the shaft end disposed proximate the axle portion. The constant velocity joint also includes a spacer, the spacer having an inner surface disposed on the axle portion and an outer surface having the shaft end of the boot disposed thereon.2011-03-10
20110059804FIXED-TYPE, CONSTANT-VELOCITY UNIVERSAL JOINT - Provided is a fixed type constant velocity universal joint which is capable of achieving the following even at the time of an unexpected high-angle operation, in particular, even when an angle expected during use of a constant velocity universal joint is exceeded: reduction of stress generated when balls and edge portions interfere with each other, suppression of chipping of the edge portions, and prolongation of a service life of the joint as a whole. The fixed type constant velocity universal joint includes: an outer joint member having an inner surface (2011-03-10
20110059805 Seesaw2011-03-10
20110059806SUSPENSION SWING DEVICE - A suspension swing device includes a supporting beam (2011-03-10
20110059807COMPONENTS FOR EXTREME SPORTS COURSES - An extreme sports component having a support and at least a first member defining a maneuvering surface. The support and at least first member are operatively joined through at least one member on each of the support and at least first member that cooperate with each other so as to maintain the support and at least first member in a predetermined operative relationship. The support and at least first member are maintained in the predetermined operative relationship without requiring that any anchoring element be directed through the maneuvering surface.2011-03-10
20110059808GOLF CLUB WITH DIRECTIONAL BASED GRAPHIC - A golf club having at least one directional based graphic on the golf club it disclosed. More specifically, the golf club in accordance with the present invention will have at least one directional based graphic that will only be visible when the golf club is oriented in a desirable direction while staying invisible in all other undesirable directions.2011-03-10
20110059809Caddy rite golf club kit - The Caddy Rite Golf Club Kit consists of a single golf club that has an interchanging connection system located where the club head connects with the club shaft at the club head hosel thereby allowing any golf club head to be interchanged with the golf club shaft. The interchanging connection system is a two piece connector consisting of a male portion that is inserted and bonded into the club shaft lower end and a mating female portion that is inserted and bonded into the top of the hosel of a golf club head. Any golf club head or set of golf club heads modified with the female portion of the connector can be attached to a golf club shaft that has been modified to include the male portion of the connector. The interchange of one club head with another can be accomplished in less than fifteen seconds while the golfer is moving to advance his/her ball. The Kit consists of one club shaft and a typical number of club heads (4 iron, 5 iron, 6 iron, 7 iron, 8 iron, 9 iron, putter, sand wedge, pitching wedge, a #1 driver, and a #3 driver).2011-03-10
20110059810CLUBHEAD WITH EXTERNAL HOSEL - A golf club head consisting of a striking face, a soleplate, a crown, and a skirt connecting the face, the soleplate and the crown. A flange is placed at a selected location on the periphery of the skirt. Incorporated into the flange is a hosel, positioned to be displaced from the club head, for receiving the shaft of the golf club. The area of the skirt covered by the flange has a length versus height ratio.2011-03-10
20110059811GOLF BALLS HAVING A LOW MODULUS HNP LAYER AND A HIGH MODULUS HNP LAYER - The present invention is directed to golf balls consisting of a multi-layer core and a cover. The multi-layer core consists of a center and an outer core layer that are both soft relative to a hard intermediate core layer. The outer core layer is preferably thin relative to the center and the outer core layer. The multi-layer core includes at least one layer formed from a low modulus HNP composition and at least one layer formed from a high modulus HNP composition.2011-03-10
20110059812MULTI-LAYER GOLF BALL - Multi-layer golf balls having a relatively hard outer core surrounding a relatively soft, low compression inner core are provided. The inner core generally has a compression of less than 50 and the inner core and outer core generally have a combined dual core compression of 50 or greater. The outer core generally has a Shore C hardness of 80 or greater. A cover, which can be a single-, dual-, or multi-layer cover, is provided to surround the outer core. A moisture barrier layer is optionally provided between the outer core and the cover. The moisture vapor transmission rate of the moisture barrier layer is preferably less than the moisture vapor transmission rate of the cover.2011-03-10
20110059813Golf ball dimples having circumscribed prismatoids - The present invention relates to golf balls, specifically, to a golf ball with multifaceted depressions comprising two discrete geometries surrounded by a first perimeter. A second perimeter is circumscribed within the first and surrounds prismatoid depressions or protrusions. Primarily the first and second perimeters are circular and the depressions or protrusions are based on a polyhedral prismatoid having a minimum of three and a maximum of twelve edges, wherein the ratio of the first and second diameters is between 0.25 to 0.90.2011-03-10
20110059814Baseball and Softball Retrieval Device - A ball retrieval device configured to receive one or more balls from a surface. The ball retrieval device comprises a housing including a first end for receiving one or more balls from a surface and a second end for dispensing said one or more balls from said housing. The ball retrieval device further comprises a retention assembly attached to the first end comprising (a) an expanded foot attached to first end of said housing and graduating in diameter from the first end to the base of said expanded foot; and (b) an interchangeable rubber cap fitted and secured over or into the base of said expanded foot.2011-03-10
20110059815Attachable Soccer Rebound Net - This invention provides a lightweight, portable rebound net from an elastic material that can be attached to an existing regulation-sized soccer goal frame by a single person without the use of a ladder. It has the ability to be tightened quickly to create tension and prevent a ball from slipping under the net with a single mechanism. It provides a rebound net for recreational use with properties like that of a training net available to sports teams. It can be used for soccer or adapted for any other sport for which it would be useful to rebound a ball rather than retrieving it during practice or play. It can be adapted to convert to a catch net without rebound properties in situations for which that would be desirable.2011-03-10
20110059816REBOUNDER AND METHOD OF USE - A rebounder for rebounding a ball includes a base; a frame pivotally connected to the base for adjusting an angle of the frame relative to the base, the frame including a first member having a first maximum dimension and a second member having a second maximum dimension less than the first member, the second member structurally supported by the first member; a rebounding mat; a plurality of springs coupling the rebounding mat to the first member, and wherein the second member is disposed forward of the springs and configured to protect the springs from contact by the ball.2011-03-10
20110059817MODULAR TABLE TENNIS GAME - A modular table tennis game includes a plurality of paddles, a table tennis ball, and an adjustable table, or multiple adjustable tables. The table(s) may be mounted on a support system such as a tripod or other support structure that allows the table(s) to be adjusted in height and tilt. The top of the table(s) may have an opening or openings larger than the table tennis ball penetrating therethrough.2011-03-10
20110059818Sport game - A plurality of articles for playing a sport game, the plurality of articles including a game ball, a plurality of goal rods and a sport court having a court top, a court base, two court sides and two court ends which define a game space, wherein the court top includes open areas on each end of the court top, wherein the open areas are separated by a studded area, the court base is divided into four sections, wherein the four sections include a goal zones separated by neutral zones, each of the two court sides include a flat portion and a studded portion, and each of the two court ends includes a goal opening.2011-03-10
20110059819MODIFIED SOCCER GAME USING FORWARD LINES - A modified soccer (“football”) field layout and associated modified method of playing soccer on the modified soccer field layout are described. The modified soccer field layout is approximately the same size as a conventional soccer field layout. In one example, the modified soccer field layout also has two Forward Areas and two Forward Lines. In one example, the method of playing soccer on the modified soccer field includes at least one associated Forward Area Soccer Rule.2011-03-10
20110059820Apparatus for deterring modification of sports equipment - The present invention relates to an apparatus for playing ball sports including softball. More particularly, the present invention relates to an apparatus for deterring the modification of ball bats. The bat comprises a barrel, a sweet spot, a transition area, a handle, and an end knob. Within the barrel are found supports used to reinforce the structural integrity of the bat to deter users from crushing the bat, causing the bat to fall outside the legal classification of bats allowed by the Amateur Softball Association of America (ASA). The supports are made out of a lightweight durable composition. The supports are held in place by a retaining member. Multiple supports and retaining members may be used.2011-03-10
20110059821INFINITELY VARIABLE TRANSMISSION - Transmission systems, assemblies, and components are described. In particular, aspects of the present disclosure relate to an infinitely variable transmission that maintains constant tooth engagement during changes in gear ratio. In one aspect, a transmission includes an axially movable sheave coupled to a chain. The sheave rotates around a drive axis. At least partially within the sheave is a set of moon gears. The moon gears orbit around the drive axis and are rotatable around respective internal axis. As the sheave moves axially, the chain and the set of moon gears move radially to define different gear ratios, with the gear ratios being changeable in infinitely small increments. A synchronization system moves the set of moon gears radially to correspond to the axial position of the sheave. A correction system optionally controls rotation of the moon gears to rotate teeth of the moon gears into alignment with the chain.2011-03-10
20110059822Powder Forged Differential Gear - A differential assembly, bevel gears for the assembly, and a method of making the bevel gears are disclosed. The bevel gears have a form which provides for high power density transfer.2011-03-10
20110059823MULTI-SPEED TRANSMISSION - A transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices may include clutches and at least one brake.2011-03-10
20110059824MODE CHANGING DEVICE FOR A POWER BRANCHING TRANSMISSION - A device for changing the mode of a power-branching transmission, that includes a casing to be connected to the transmission, an epicyclic train with three inputs, a mechanism blocking a first input relative to the casing that can be selectively actuated to establish a first operation mode of the transmission, and a kinematic chain provided with a connection mechanism connecting the first input with a second input, when the connection mechanism is actuated, to establish a second operation mode of transmission. The kinematic chain includes at least one meshing between two gears.2011-03-10
20110059825EXERCISE EQUIPMENT USAGE MONITORING METHOD AND APPARATUS - A method of monitoring the use of exercise equipment at an exercise facility having a plurality of items of exercise equipment, the method comprising the steps of: providing a plurality of usage monitors, each associated with an item of exercise equipment, monitoring the usage of the said plurality of items of exercise equipment concurrently using the said usage monitors, and thereby calculating, for at least some of the items of exercise equipment, a measure of the proportion of the period of time during which respective items of exercise equipment are used. In some embodiments, the usage monitors can detect when an item of exercise equipment is occupied, even if it is not being operated, for example using a heat sensor. A graphical representation may be prepared of the usage of items of exercise equipment at each of a plurality of locations within the exercise facility.2011-03-10
20110059826COMPOSITE DIVING BOARD - A composite diving board comprising a composite laminate of fibers in a matrix.2011-03-10
20110059827BOXING TRAINING DEVICE - A boxing training device including a support frame, a first set of pads each resiliently secured relative to the support frame and a second set of pads each resiliently connected relative to the support frame. The first set of pads comprises a plurality of pads located at multiple heights having faces angled towards a right hand side of a boxer for receiving right handed blows and the second set of pads comprises a plurality of pads located at multiple heights having faces angled towards a left hand side of a boxer for receiving left handed blows.2011-03-10
20110059828A K PAC - A portable exercise apparatus comprising a member, for placing on the user's back, a shoulder strap, extending out of the member, for passing around the user's shoulder, a torso strap, extending out of the member, for passing around the user's torso, wherein the torso strap has a first strap portion and a second strap portion, a resistance band, a latching member, having a first latch portion and a second latch portion, wherein the latch portions are interlockable and the first latch portion is provided on the first strap portion and the second latch portion is provided on the second strap portion, and a locking member, for securing the latch portions in an interlocked position2011-03-10
20110059829COMBINATION GRIP FOR AN EXERCISE DEVICE - An exercise device having many advantageous features is described, including the ability to provide a combination of grips to the user, and the ability to easily mount the device to a wall. One exercise device described is an inelastic resistance device having a combination grip that includes hand grips and a loop. The hand grip and loop may be used as a foot grip, or alternatively, just the hand grip can be used by the hand. The selection of a specific accessory grip allows the user to exercise by specific body parts and provides for a greater number of possible exercises.2011-03-10
20110059830Exercise mat with removable portion - An exercise mat that provides cushioning and support to a participant, the mat having a relatively large main body, a substantially triangularly-shaped recess positioned on the underside of the mat, the recess not passing through the upper surface of the mat, and a substantially triangularly-shaped removable insert member retained within the recess.2011-03-10
20110059831METHOD AND APPARATUS FOR INCORPORATING OBJECTS INTO CIGARETTE FILTERS - Cigarette filter rods having individual objects positioned at predetermined intervals therein are prepared by transferring the individual objects from a rotating horizontal pan to a rotating vertical wheel and then depositing the object into a web of filter tow. Each object is positioned within the moving web of tow. The web filter material and the objects positioned within the web are introduced into a rod-forming unit wherein the rod is formed. The rate of feed of the filter tow, the rate of rotation of the horizontal pan and the vertical wheel are controlled relative to one another such that objects are positioned at predetermined intervals along the rod. Cigarette filter elements having well controlled amounts of flavorant contained therein can be made from the rods.2011-03-10
20110059832Gripping Element of a Bag for Pharmaceutical Products - A gripping element of a bag for pharmaceutical products is provided with two gripping devices adapted to withhold two opposite edges of the bag itself.2011-03-10
20110059833BAG MANUFACTURING AND PACKAGING APPARATUS - A bag manufacturing and packaging apparatus is adapted to form a strip film into a cylindrical film. The bag manufacturing and packaging apparatus includes a sealing unit with a pair of sealing members facing each other to seal an end portion of the cylindrical film therebetween to package an article. Each of the sealing members includes a sealing jaw, a heating unit, and a heat insulating member. The sealing jaw has a heat generating surface, and configured and arranged to seal the cylindrical film on the heat generating surface. The heating unit is configured and arranged to heat the heat generating surface of the sealing jaw. The heat insulating member insulates the heat conduction from the heating unit to a direction other than a direction toward the heat generating surface of the sealing jaw.2011-03-10
20110059834Centrifuge for separating of whole blood into blood components as well as fluidically communicating containers for insertion into the centrifuge, as well as a method for obtaining a highly enriched thrombocyte concentrate out of whole blood - The invention refers to a centrifuge for separating whole blood into its blood components and a method for extracting a highly enriched thrombocyte concentrate out of whole blood. For this purpose, the centrifuge comprises a closed loop and/or open-loop control unit as well as a drive unit coupled to the closed loop and/or open-loop control unit, a rotor (2011-03-10
20110059835CENTRIFUGE - According to an aspect of the present invention, there is provided a centrifuge including: a motor; a rotor chamber that accommodates a rotor rotated by the motor thereinside; a vacuum pump that sucks air from the rotor chamber to reduce a pressure therein; and a controller that controls the centrifuge to operate in: (1) a normal operation mode in which the rotor is rotated while activating the vacuum pump; and (2) a pulsed operation mode in which the rotor is rotated without activating the vacuum pump.2011-03-10
20110059836Lithium Silicate Materials - Lithium silicate materials are described which can be easily processed by machining to dental products without undue wear of the tools and which subsequently can be converted into lithium silicate products showing high strength.2011-03-10
20110059837METHOD FOR PRODUCING SYNTHETIC QUARTZ GLASS - In a known exterior deposition method for producing synthetic quartz glass, amorphous quartz glass powder particles (2011-03-10
20110059838DIELECTRIC CERAMIC COMPOSITION - Dielectric ceramic composition comprising a barium titanate including barium titanate having hexagonal structure as a main component, and an element “M”, an effective ionic radius of the “M” is within ±20% with respect to an effective ionic radius of 12-coordinated Ba2011-03-10
20110059839TRANSLUCENT POLYCRYSTALLINE SINTERED BODY, METHOD FOR PRODUCING THE SAME, AND ARC TUBE FOR HIGH-INTENSITY DISCHARGE LAMP - A translucent polycrystalline sintered body is mainly composed of an alumina, is suitable for the manufacture of an arc tube for a high-intensity discharge lamp, and has an average grain diameter of 35 to 70 μm, preferably 50 to 60 μm. In a case where the sintered body is in a 0.5-mm-thick flat plate shape, the in-line transmittance of the sintered body is 30% or more, preferably 50% or more. In this case, the ratio between maximum and minimum in-line transmittance values is 2:1 to 1:1 in the visible region of 360 to 830 nm. The bending strength of the sintered body is 250 MPa or more, preferably 300 MPa or more.2011-03-10
20110059840NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS - The present invention provides polymerization catalyst compositions employing novel dinuclear metallocene compounds. Methods for making these new dinuclear metallocene compounds and for using such compounds in catalyst compositions for the polymerization and copolymerization of olefins are also provided.2011-03-10
20110059841Photocatalytically Active Polysiloxane Coating Compositions - The invention is a coating composition comprising photocatalytic titanium dioxide particles, an opacifying agent, a silicone compound, de-HNO2011-03-10
20110059842Tungstated Zirconia Nanocatalysts - A new type of solid acid catalyst, which promises better catalytic performance than conventionally prepared supported metal oxides due to its precisely synthesized nanostructure has been described. The catalyst is nanoparticulate in form and is comprised of monolayers of tungstated zirconia of the formula, WOxZryO4-2y made by impregnating a support with zirconium and tungsten. The support catalyst is further characterized in having a tugsten monolayer between greater than 0001 W/nm2 to about 30 W/nm2.2011-03-10
20110059843POROUS BODY PRECURSORS, SHAPED POROUS BODIES, PROCESSES FOR MAKING THEM, AND END-USE PRODUCTS BASED UPON THE SAME - The present invention provides porous body precursors and shaped porous bodies. Also included are catalysts and other end-use products based upon the shaped porous bodies and thus the porous body precursors. Finally, processes for making these are provided. The porous body precursors incorporate at least a first oxophilic high oxidation state transition metal. Because the oxophilic high oxidation state transition metal is incorporated into the porous body precursors, it is thought that it will become relatively uniformly distributed therethrough, and thus, provide property enhancements to shaped porous bodies and catalysts based thereupon.2011-03-10
20110059844POROUS BODY PRECURSORS, SHAPED POROUS BODIES, PROCESSES FOR MAKING THEM, AND END-USE PRODUCTS BASED UPON THE SAME - The present invention provides porous body precursors and shaped porous bodies. Also included are catalysts and other end-use products based upon the shaped porous bodies and thus the porous body precursors. Finally, processes for making these are provided. The porous body precursors comprise a precursor alumina blend capable of enhancing one or more properties of a shaped porous body based thereupon. The need to employ modifiers to achieve a similar result may thus be substantially reduced, or even avoided, and cost savings are thus provided, as well as savings in time and equipment costs.2011-03-10
20110059845FUNCTIONALIZED SORBENT FOR CHEMICAL SEPARATIONS AND SEQUENTIAL FORMING PROCESS - A highly functionalized sorbent and sequential process for making are disclosed. The sorbent includes organic short-length amino silanes and organic oligomeric polyfunctional amino silanes that are dispersed within pores of a porous support that form a 3-dimensional structure containing highly functionalized active binding sites for sorption of analytes.2011-03-10
20110059846SOLID FORMULATIONS OF CARBOXAMIDE ARTHROPODICIDES - Disclosed is a solid arthropodicide composition comprising by weight 2011-03-10
20110059847Herbicide Composition for Paddy Field - A herbicide composition for paddy field characterized by containing (a) a herbicidal difluoromethanesulfonamide derivative represented by the formula (I)2011-03-10
20110059848GRANULAR TURF SAFE HERBICIDAL COMPOSITIONS - Disclosed is a composition comprising (a) one or more compounds selected from the compound of Formula 1 insert Formula 1 here and salts, esters and thioesters thereof, coated on or impregnated into (b) a granular substrate material. The composition is particularly useful for controlling weeds in turf comprising warm-season turfgrasses without causing significant injury to the turfgrasses. Also disclosed is a method for controlling weeds in turf comprising a warm-season turfgrass without causing significant injury to the turfgrass, the method comprising applying a herbicidally effective amount of the composition to the turf.2011-03-10
20110059849SYNERGISTIC HERBICIDAL COMBINATION OF CLOMAZONE AND PETHOXAMID - Presented are herbicidal compositions comprising as active ingredients clomazone and pethoxamid. The combinations of these herbicidal active compounds show a synergistic effect in the control of harmful plants.2011-03-10
20110059850PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES - The invention relates to phytotoxic halogenated derivatives of benzoxazinones. The aim of the invention relates to the production of novel phytosanitary products that are suitable for agricultural weed control, based on natural chemical substances. The invention comprises novel chemical compounds having high levels of phytotoxic activity and the preparation methods thereof. Said substances are derived from natural products with the 1,4-benzoxazin-3-one skeleton involved in different chemical defense interactions in plants. The inventive compounds have suitable phytotoxic activity levels for use in weed control and for use as stable models for the development of novel phytosanitary products based on the 1,4-benzoxazin-3-one skeleton.2011-03-10
20110059851SHOC2 Mutations Causing Noonan-Like Syndrome With Loose Anagen Hair - The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is an A-to-G transition at position 4 resulting in a mutation at position 2 of SHOC2 amino acid sequence from serine to glycine. The invention also provides related sequences and kits.2011-03-10
20110059852COMPOSITIONS AND METHODS FOR TREATING HAEMATOLOGICAL PROLIFERATIVE DISORDERS OF MEYLOID ORIGIN - The disclosure relates to methods and compositions effective in the diagnosis, prognosis and treatment of human hematopoietic cancers. In particular, the disclosure provides tumor-associated genes that encode for cytokine receptors that are differentially expressed in hematopoietic tumor cells of myeloid origin compared with other cells, e.g., normal stem cells.2011-03-10
20110059853Method And Computer System For Assessing Classification Annotations Assigned To DNA Sequences - For assessing classification annotations assigned to DNA sequences stored in a reference database, the DNA sequences are grouped by species using established classification schemes. Subsequently, a measure of distance between pairs of DNA sequences is determined by aligning the respective sequences and determining the measure of distance based on a score of similarity between the aligned DNA sequences. Determined are one or more centroid sequences which have the shortest aggregate measure of distance to the other DNA sequences in the respective group (species). Assigned to the DNA sequences as a quantitative confidence level for their classification annotations is in each case the measure of distance between the respective DNA sequence and the centroid sequence. The assessment and rating of the classification annotations with these confidence levels make it possible to provide to a user a quantitative indication of the degree of representativeness of a DNA sequence for a particular species.2011-03-10
20110059854DIAGNOSTIC AND PROGNOSTIC TESTS - The invention provides methods for diagnosing biological states or conditions based on ratios of gene expression data from tissue samples, such as cancer tissue samples. The invention also provides sets of genes that are expressed differentially in malignant pleural mesothelioma. These sets of genes can be used to discriminate between normal and malignant tissues, and between classes of malignant tissues. Accordingly, diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression also are provided.2011-03-10
20110059855Use of adiponectin for the diagnosis and/or treatment of presbycusis - The present invention relates to mutations located within the gene coding for adiponectin, said mutations being associated with presbycusis. The present invention further relates to adiponectin polynucleotides comprising such mutations, to adiponectin polypeptides encoded by such polynucleotides, and to methods of diagnosing and/or treating presbycusis using adiponectin polynucleotides, adiponectin polypeptides and/or ADIPOR2 polypeptides.2011-03-10
20110059856IN VITRO DIAGNOSTIC METHOD FOR THE DIAGNOSIS OF SOMATIC AND OVARIAN CANCERS - Method of using one element chosen among a nucleic acid molecule, a fragment of the nucleic acid molecule and a variant of the nucleic acid molecule for the in vitro or ex vivo diagnosis of any type of somatic or ovarian cancers, wherein at least one of any of the above described elements is abnormally expressed in cancer cells of at least one type of the somatic or ovarian cancers, and wherein each type of somatic or ovarian cancer cells abnormally expresses at least one of the above described elements.2011-03-10
20110059857MARKERS OF ACUTE KIDNEY FAILURE - The present invention relates to the method of determining the risk of acute kidney injury comprising determining the amount of a marker selected from VCAN, NRP1, CCL2, CCL19, COL3A1, GZMM or any combination thereof in a sample.2011-03-10
20110059858NEW BIOMARKER FOR DIAGNOSIS, PREDICTION AND/OR PROGNOSIS OF SEPSIS AND USES THEREOF - The present invention provides kits and methods for the diagnosis, prognosis and prediction of sepsis in a subject using the expression level of the TREML-1 biomarker as an indication of the condition of the patient, alone or in combination with further sepsis markers.2011-03-10
20110059859Molecule Detecting System - The invention disclosed here has several key elements: direct probe-on-sensor detection, mesh probe, and mesh reporter. Furthermore, the mesh probe and reporter shall have some physical cross-linking between the polymer backbone(s), either covalently or non-covalently. In combination, this invention enables one to build an ultra-sensitive, low-cost, and highly portable system for molecular detection. Among its many potential applications is a direct detection of nucleic acids in crude lysate in a multiplex format, without the requirements for nucleic acids extraction and amplification. Such an improvement is likely to change the practice of genotyping and gene expression profiling done in a clinic setting. Another application is an ultrasensitive ELIZA assay in a multiplex format.2011-03-10
20110059860SYSTEMS AND METHODS FOR BIOPOLYMER ENGINEERING - Methods, computer systems, and computer program products for biopolymer engineering. A variant set for a biopolymer of interest is constructed by identifying, using a plurality of rules, a plurality of positions in the biopolymer of interest and, for each respective position in the plurality of positions, substitutions for the respective position. The plurality of positions and the substitutions for each respective position in the plurality of positions collectively define a biopolymer sequence space. A variant set comprising a plurality of variants of the biopolymer of interest is selected. A property of all or a portion of the variants in the variant set is measured. A sequence-activity relationship is modeled between (i) one or more substitutions at one or more positions of the biopolymer of interest represented by the variant set and (ii) the property measured for all or the portion of the variants in the variant set. The variant set is redefined to comprise variants that include substitutions in the plurality of positions that are selected based on a function of the sequence-activity relationship.2011-03-10
20110059861ANALYSIS OF CELL NETWORKS - The present invention provides an approach for the determination of activation state of a plurality of discrete cell populations and/or the state of one or more cellular networks in an individual. The status of a plurality of discrete cell populations and/or the state of one or more cellular networks can be correlated with the diagnosis, prognosis, choice or modification of treatment, and/or monitoring of a condition2011-03-10
20110059862Expression Cloning Methods In Filamentous Fungi - Methods for screening a polynucleotide library for a polypeptide with a property of interest in a filamentous fungal host cell, in a manner which allows quick and easy subsequent characterization of the polypeptide, using an expression cloning vector comprising at least a polynucleotide encoding a selectable marker in which the translation initiation start site of the marker-encoding sequence comprises a crippled consensus Kozak sequence, a fungal replication initiation sequence, and a promoter with a cloning-site into which the library is cloned, and a transcription terminator.2011-03-10
20110059863IN VIVO EVOLUTION OF HYDROGENASES USING A HYDROGEN-SENSING SYSTEM - Provided herein are methods for measuring H2 production by a hydrogenase. Also provided are methods for evolving a hydrogenase or hydrogen-sensing system by comparing the level of production of H2 by the hydrogenase to the level Of H2 produced by a wild-type hydrogenase cultured under the same conditions and selecting a microorganism with increased H2 production over the H2 production by a microorganism having a wild-type hydrogenase. Further provided herein are microorganisms and plasmids comprising a hupSL promoter coupled with a reporter gene.2011-03-10
20110059864Sequence Determination By Use Of Opposing Forces - The present teachings relate to systems, methods, and the like, for analyzing biological polymers, by use of opposing forces. Among other things, the present teachings can be used to determine sequence information, such as in genetic sequencing and genotyping applications. Various embodiments are described for efficient, high throughput sequencing of nucleic-acid molecules, such as DNA. Various embodiments are described wherein nucleic-acid sequence information is determined without the need or use of extrinsic labels. As well various embodiments of methods, systems, and the like, are described, which can provide long and accurate read lengths for low-cost nucleic acid sequencing.2011-03-10
20110059865Modified Molecular Arrays - The invention relates to the preparation of a hydrogel surface useful in the formation and manipulation of arrays of molecules, particularly polynucleotides and to the chemical modification of these and other arrays. In particular, the invention relates to a method of preparing a hydrogel immobilised to a solid support comprising polymerising on the support a mixture of a first comonomer which is acrylamide, methacrylamide, hydroxyethyl methacrylate or N-vinyl pyrrolidinone and a second comonomer which is a functionalised acrylamide or acrylate.2011-03-10
20110059866Multiplex detection of nucleic acids - Methods of detecting nucleic acids, including methods of detecting two or more nucleic acids in multiplex branched-chain DNA assays, are provided. Nucleic acids captured on a solid support are detected, for example, through cooperative hybridization events that result in specific association of a label with the nucleic acids. Compositions, kits, and systems related to the methods are also described.2011-03-10
20110059867FUNCTIONALIZED POLYDIACETYLENE SENSORS - A microarray includes a solid substrate having a surface, the surface having a plurality of binding spots and a plurality of reaction moieties bound to the binding spots. A reaction moiety includes a plurality of polyacetylene monomers, the polyacetylene monomers having a first coupling region and a second coupling region, the first coupling region having a first functional group operable to bind to the binding spot and the second coupling region comprising a second functional group operable to bind to an accessory molecule; and an accessory molecule having a binding region and an analyte reaction region, the analyte reaction region operable to selectively bind to the target analyte, and the binding region operable to bind to the second coupling region of the polyacetylene monomer. Upon binding a target analyte with the reaction moiety, a color change from the polyacetylene monomer occurs and the reaction moiety produces fluorescence.2011-03-10
20110059868PROCESS FOR AMPLIFYING NUCLEIC ACIDS - The present invention relates to a process for synthesizing or amplifying efficiently a nucleic acid comprising a target nucleic acid sequence. In the process according to the present invention, a primer comprising in its 3′-end portion a sequence (Ac′) which hybridizes a sequence (A) in the 3′-end portion of the target nucleic acid sequence, and in the 5′-side of said sequence (Ac′) a sequence (B′) which hybridizes the complementary sequence (Bc) of a sequence (B) positioned in the 5′-side of said sequence (A) on the target nucleic acid sequence, wherein {X−(Y−Y′)}/X is in the range of −1.00 to 1.00, in which X denotes the number of bases in said sequence (Ac′), Y denotes the number of bases in the region flanked by said sequences (A) and (B) in the target nucleic acid sequence, and Y′ denotes the number of bases in an intervening sequence between said sequences (Ac′) and (B′) (Y′ may be zero).2011-03-10
20110059869Method for Increasing Enzymatic Reactivity - An object of the invention is to provide a method for increasing enzymatic reactivity to a target substance immobilized on a support; and a method for reducing or suppressing an inhibitory effect of a support on enzymatic reaction. The above object is achieved by a method for increasing enzymatic reactivity to a target substance immobilized on a support by allowing at least one substance selected from the group consisting of saccharides, amino acids, polyhydric alcohols and derivatives thereof to exist; and a method for reducing or suppressing an inhibitory effect of a support immobilized with a target substance on enzymatic reactivity to the target substance by allowing at least one substance selected from the group consisting of saccharides, amino acids, polyhydric alcohols and derivatives thereof to exist.2011-03-10
20110059870Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.2011-03-10
20110059871Graphene Compositions And Drilling Fluids Derived Therefrom - Drilling fluids comprising graphenes and nanoplatelet additives and methods for production thereof are disclosed. Graphene includes graphite oxide, graphene oxide, chemically-converted graphene, and functionalized chemically-converted graphene. Derivatized graphenes and methods for production thereof are disclosed. The derivatized graphenes are prepared from a chemically-converted graphene through derivatization with a plurality of functional groups. Derivatization can be accomplished, for example, by reaction of a chemically-converted graphene with a diazonium species. Methods for preparation of graphite oxide are also disclosed.2011-03-10
20110059872COMPOSITIONS AND METHODS FOR CONTROLLING THE STABILITY OF ETHERSULFATE SURFACTANTS AT ELEVATED TEMPERATURES - The present invention describes the method of making an ether sulfate surfactant solution hydrolytically stable by adding one or more alkalinity generating agents at levels greater than 0.05%. The surfactant solutions of the present invention have half-lives >8 months at 100° C. and find uses in EOR applications, environmental cleanups, detergent industry, and any other surfactant based high temperature applications.2011-03-10
20110059873PROCESS OF USING HARD BRINE AT HIGH ALKALINITY FOR ENHANCED OIL RECOVERY (EOR) APPLICATIONS - The present invention describes the use of EDTA and/or alkali treated hard brine at high pH for making ASP formulations for EOR applications.2011-03-10
20110059874HYDROPHILIC COATING - The invention relates to a coating formulation for preparing a hydrophilic coating, wherein the hydrophilic coating formulation comprises (a) at least one multifunctional polymerizable compound 5 (b) at least one Norrish Type I photoinitiator; and (c) at least one Norrish Type II photoinitiator.2011-03-10
20110059875GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND THE CONSTANT VELOCITY JOINT - The invention provides a grease composition that can improve the durability and the temperature control properties of constant velocity joints and reduce the rotating torque at low temperatures, and a constant velocity joint where the above-mentioned grease composition is packed. The grease composition for constant velocity joints includes (a) a base oil containing a synthetic oil, (b) a thickener, (c) zinc dithiophosphate, (d) molybdenum dialkyl dithiocarbamate sulfide, and (e) zinc dialkyl dithiocarbamate.2011-03-10
20110059876OIL-IN-WATER EMULSION COMPOSITION - An oil-in-water type (O/W) emulsion lubricant composition includes safe and renewable components that do not have environmental load, exhibits excellent lubrication properties, has excellent handling capability, is economical, and may be applied to tribological fields.2011-03-10
20110059877LUBRICATING COMPOSITION FOR A FOUR-STROKE ENGINE WITH LOW ASH CONTENT - The present disclosure relates to a lubricating composition for a four-stroke engine, with low ash content including: 2011-03-10
20110059878Lubricant Oil Compositions To Optimize Internal Combustion Engine Performance - The present disclosure relates to lubricant oil compositions formed from base stock oils to optimize internal combustion engine performance. Base stock oils are identified that have selected cetane number characteristics and relatively reduced reactivity to improve their associated combustion characteristics and reduce engine knock without the need to modify the engine fuel or engine parameters such as compression ratio and/or ignition timing. The base stocks may specifically include esters of dicarboxylic acids, esters of trimellitic anhydride and/or alklyated naphthalene compounds.2011-03-10
20110059879Industrial and automotive grease and process for its manufacture - A lubricating grease composition is disclosed. In one embodiment, the lubricating grease comprises at least one Group I oil, at least one Group II oil, a hydrophilic copolymer, and a soap thickener. The thickener is dispersed into at least one Group I oil during a cooking phase and the at least one Group II oil is introduced during a finishing phase. A method for making a lubricating grease is also disclosed. The method comprises obtaining at least one Group I oil, obtaining at least one Group II oil, obtaining a hydrophilic copolymer, obtaining a soap thickener, and mixing the at least one Group I oil, the least one Group II oil, the polymer and the soap thickener to form a grease wherein the thickener is dispersed into the at least one Group I oil during a cooking phase and at least one Group II oil is introduced during a finishing phase.2011-03-10
20110059880COMPOSITION FOR COMPRESSOR WORKING FLUID FOR APPLICATIONS WITH SOLUBLE GAS OR GAS CONDENSATES - A composition of compressor working fluid including a dissolved gas or a condensate from a dissolved gas, and a base fluid including at least a first base stock and a second base stock, wherein the viscosity difference between the first base stock and the second base stock is greater than 125 cSt, Kv 100° C. A composition of compressor working fluid including a dissolved gas or a condensate from a dissolved gas, and a base fluid including a first base stock and a second base stock, wherein the viscosity difference between the first and second base stock is greater than 40 cSt, Kv 100° C., and wherein the first and second base stocks are each polyglycol or polyalkylene glycol base derived from propylene oxide. A method of achieving favorable viscosity index for a compressor working fluid. A method of reducing dilution from gas being compressed for a compressor working fluid.2011-03-10
20110059881Sulphur Free Composition And Lubricant Composition And Methods Thereof - A composition comprises a sulphur free reaction product of: (a)(i) a hydrocarbyl substituted aromatic compound containing an acidic group selected from the group consisting of a carboxylic group, a hydroxyl group and mixtures thereof; and (a)(ii) an organic nitrogen-containing base reacted with the acidic group. The composition is obtained by a preparatory process and is useful in a method for lubricating an internal combustion engine to include where the lubricant has reduced levels of sulphur, phosphorus and sulphated ash.2011-03-10
20110059882SOLID-LAYERED BLEACH COMPOSITIONS AND METHODS OF USE - The present invention provides a method for cleaning dentures by contacting the dentures with a solid, multi-layered composition having at least two parts in water. The first part of the composition comprises a) calcium hypochlorite, magnesium hypochlorite and mixtures thereof, b) a builder, c) a water-soluble polymer, d) an acid, and e) wherein the first part does not contain sodium hypochlorite, lithium hypochlorite, potassium hypochlorite and mixtures thereof. The second part comprises a) a functional ingredient, b) a builder or filler, and c) wherein the second part does not contain any oxidant.2011-03-10
20110059883Methods to Improve the Compatibility and Efficiency of Powdered Versions of Microfibrous Cellulose - A method for improving the performance of a powdered microfibrous cellulose (MFC) composition is provided. The method involves degrading a co-agent in the powdered MFC composition using a polymer degrader. The polymer degrader does not substantially degrade the MFC.2011-03-10
20110059884USE OF ISOSORBIDE ETHERS IN DETERGENTS AND CLEANERS - The application pertains to the use of isosorbide ethers according to general formula (I)2011-03-10
20110059885TREATMENT OF DISEASES AND CONDITIONS MEDIATED BY EICOSANOIDS - The method of the invention relates to an OmCI polypeptide or a polynucleotide encoding an OmCI polypeptide for the treatment of a disease or condition mediated by a leukotriene or hydroxyeicosanoid.2011-03-10
20110059886HCV NS3-NS4A Protease Inhibition - The present invention relates to inhibiting the activity of non-genotype 1 hepatitis C virus (HCV) NS3-NS4A protease activity. More particularly, the invention relates to inhibiting the activity of the protease from HCV genotype-2 or HCV genotype-3. The methods of the invention emply inhibitors that act by interfering with the life cycle of the HCV and are also useful as antiviral agents. The invention further relates to compositions comprising such compounds either for ex vivo use or for administration to a patient suffering from genotype-2 or genotype-3 HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.2011-03-10
20110059887MEAL-TIME INSULIN ANALOGUES OF ENHANCED STABILITY - A method treating a patient includes administering a physiologically effective amount of a fibrillation-resistant insulin analogue or a physiologically acceptable salt thereof to the patient. The fibrillation-resistant insulin analogue or a physiologically acceptable salt thereof, contains an insulin A-chain sequence modified at position A8 and an insulin B-chain sequence or an analogue thereof. The fibrillation-resistant insulin analogue may exhibit thermodynamic stability similar to or exceeding that of wild-type human insulin and displays a susceptibility to fibrillation similar to or exceeding that of wild-type human insulin. An insulin analogue may display greater in vitro insulin receptor binding than normal insulin while displaying binding to IGFR less than twice that of normal insulin and less than that of fast-acting insulin analogs. The fibrillation-resistant insulin may be used to treat a patient by subcutaneous injection or by using an implantable or external insulin pump, due to its fibrillation resistance.2011-03-10
20110059888METASTIN DERIVATIVES AND USE THEREOF - The present invention provides stable metastin derivatives having excellent biological activities (a cancer metastasis suppressing activity, a cancer growth suppressing activity, a gonadotropic hormone secretion stimulating activity, sex hormone secretion stimulating activity, etc.). By substituting the constituent amino acids of metastin with specific amino acids, the metastin derivatives of the present invention achieve more improved blood stability, solubility, etc., reduced gelation tendency, improved pharmacokinetics, as well as exhibit an excellent cancer metastasis suppressing activity or a cancer growth suppressing activity. The metastin derivatives of the present invention also have a gonadotropic hormone secretion suppressing activity, sex hormone secretion suppressing activity, etc.2011-03-10
20110059889PEPTIDES THAT BLOCK THE BINDING OF IgG TO FcRn - The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates to methods of using and methods of making the peptides of the invention.2011-03-10
20110059890EXPRESSION VECTORS AND CELL LINES EXPRESSING VASCULAR ENDOTHELIAL GROWTH FACTOR D, AND METHOD OF TREATING MELANOMAS - This invention relates to expression vectors comprising VEGF-D and its biologically active derivatives, cell lines stably expressing VEGF-D and its biologically active derivatives, and to a method of making a polypeptide using these expression vectors and host cells. The invention also relates to a method for treating and alleviating melanomas or tumors expressing VEGF-D and various diseases.2011-03-10
20110059891ALPHA-MSH THERAPIES FOR TREATMENT OF AUTOIMMUNE DISEASE - Methods and compositions for the enteral treatment of autoimmune disease such a multiple sclerosis with polypeptide therapeutics. Enteral therapeutics comprise monomeric alpha-MSH polypeptides such as ACTH. Therapeutic formulations of the invention may be used to reduce the incidence or severity of autoimmune disease. For instance methods for the oral treatment of multiple sclerosis with alpha-MSH and ACTH are described.2011-03-10
20110059892Cosmetic preparations containing PTH fragments - A cosmetic or pharmaceutical composition includes a peptide parathyroid hormone fragment, derivatives thereof, salts thereof, and combinations thereof, where the peptide fragment conforms to the structure2011-03-10
20110059893COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS - The invention relates to compounds of structural formula (I):2011-03-10
20110059894Factor VII Polypeptides for Preventing Formation of Inhibitors in Subjects with Haemophilia - The invention provides a method for preventing formation of inhibitors to blood coagulation factor VIII or factor IX in a subject having haemophilia, the method comprising administering (via intravenous, subcutaneous, intradermal, or intramuscular routes) to a previously untreated subject an effective dosage of factor VIIa or a factor VII-related polypeptide.2011-03-10
20110059895MODULATION OF FACTOR 9 EXPRESSION - Disclosed herein are antisense compounds and methods for decreasing Factor 9 and increasing clotting time in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 9 include thrombosis, embolism, thromoboembolism such as deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke.2011-03-10
20110059896USE OF FURIN CONVERTASE INHIBITORS IN THE TREATMENT OF FIBROSIS AND SCARRING - The present invention relates to use of convertase inhibitors for the reduction of scarring during the healing of wounds and also for reducing fibrosis in the treatment of fibrotic conditions.2011-03-10
20110059897Methods for treating a skin wound - A therapeutic method for treating a skin wound involving administering to a patient in need thereof a composition containing pharmaceutically effective amounts of the following components: (1) a peptide consisting of the amino acid sequence represented by Ser-Ser-Ser-Arg (SEQ ID NO: 1) or pharmaceutically acceptable salts thereof and (2) a peptide consisting of the amino acid sequence represented by Phe-Gly-Leu-Met-NH2011-03-10
20110059898PRO-OXIDANT ANTI-CANCER COMPOUNDS - This invention relates to anti-cancer compounds and to methods for treating or preventing cancer. In particular, the invention concerns pro-oxidant anti-cancer compounds, such as pro-oxidant forms of vitamin E, that selectively interact with complex II of the mitochondrial respiratory chain of cancerous cells, generate reactive oxygen species and induce apoptosis of those cells.2011-03-10
20110059899Kruppel-like factor 6 (KLF6), a tumor suppressor protein, and diagnostics, therapeutics, and screening based on this protein - The present invention relates to identification of tumor suppressor activity of a protein, KLF6 (KLF6), and to related diagnostic and therapeutic compositions and methods. The discovery of this tumor suppressor activity provides screening targets as well, particularly screening for compounds that overcome gene inactivation or alteration.2011-03-10
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