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10th week of 2013 patent applcation highlights part 45
Patent application numberTitlePublished
20130059885Method For Preparation Of Pitavastatin and Pharmaceutical Acceptable Salts Thereof - The present invention discloses a compound, which is alkali or alkaline earth metal salts of pitavastatin, wherein the alkali or earth metal comprise one or more of magnesium, zinc, potassium, strontium and barium.2013-03-07
20130059886POLYMORPHIC FORM OF FEXOFENADINE HYDROCHLORIDE, INTERMEDIATES AND PROCESS FOR ITS PREPARATION - The present invention relates to a novel polymorphic form of Fexofenadine hydrochloride, to a process for preparing it, to pharmaceutical compositions containing it, as well as its use. The invention also relates to intermediates useful for the preparation of Fexofenadine hydrochloride, antihistamine drug used in the treatment of allergy symptoms.2013-03-07
20130059887SUBSTITUTED PYRIDOXINE-LACTAM CARBOXYLATE SALTS - The present invention provides salt adducts comprising at least one positively charged moiety being a pyridoxine or a derivative thereof and at least one carboxylated 5- to 7-membered lactam ring, optionally additionally substituted, methods of their preparation, and pharmaceutical compositions and medicaments comprising them. Salt adducts of the invention and compositions comprising them may be used to in the treatment of diseases or disorders associated with or inflicted by alcohol consumption.2013-03-07
20130059888MEDICAMENT FOR PROPHYLACTIC AND/OR THERAPEUTIC TREATMENT OF ALZHEIMER-TYPE DEMENTIA - A medicament for prophylactic and/or therapeutic treatment of Alzheimer-type dementia, which comprises donepezil hydrochloride and valproic acid or a salt thereof in combination.2013-03-07
20130059889ANHYDROUS LENALIDOMIDE FORM-I - Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.2013-03-07
20130059890ANTIVIRAL AGENTS - The invention relates to agents for the treatment of hepatitis C virus infection. More specifically, the invention relates to antagonists of cannabinoid type 1 receptor signalling pathway proteins and their use for the treatment of hepatitis C virus infection.2013-03-07
20130059891SUBSTITUTED N-HETEROCYCLOALKYL BIPYRROLIDINYLPHENYL AMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF - The present disclosure relates to a series of substituted N-heterocycloalkyl bipyrrolidinylphenyl amide derivatives of formula (I).2013-03-07
20130059892Compositions and Methods for Cancer Detection and Treatment - Disclosed herein are compositions and methods for cancer detection and treatment. Compounds that inhibit PRMT5 are contemplated, as are pharmaceutical compositions comprising a therapeutically effective amount of at least one PRMT5 inhibitor. In some embodiments pharmaceutical compositions further comprising at least one HDAC inhibitor are contemplated. Methods of treating disorders in a mammal by inhibiting PRMT5 by administering to a mammal, a therapeutically effective amount of a PRMT5 inhibitor are also disclosed.2013-03-07
20130059893CRYSTALLINE FORM OF THE SODIUM SALT OF 4-TERT-BUTYL-N-[4-CHLORO-2-(1-OXY-PYRIDINE-4-CARBONYL)-PHENYL]-BENZENESUL- FONAMIDE - A novel crystalline form of the sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide and pharmaceutical compositions containing the same are disclosed. Processes for the preparation thereof and methods for use thereof are also disclosed.2013-03-07
20130059894PESTICIDAL COMPOSITION AND ITS USE - A composition comprising a carboxamide compound represented by following formula (I), wherein R2013-03-07
201300598952',2-DITHIAZOL NON-NUCLEOSIDE COMPOUNDS, PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND USES AS HEPATITIS VIRUS INHIBITORS THEREOF - The present disclosure belongs to the field of pharmaceutical chemistry, and relates to a class of 2′,2-bisthiazole non-nucleoside compounds of following formula I, the preparation method and the pharmaceutical composition thereof. The compounds have both the anti-HBV and anti-HCV activities and are useful in treating hepatitides B and C. Pharmacokinetic tests showed the compounds have good bioavailability.2013-03-07
201300598965-(1H-PYRAZOL-5-YL)THIAZOLE-BASED COMPOUNDS FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE EYE - Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use. Particular compounds are of the formula (I)2013-03-07
20130059897RAPID RELEASE IRBESARTAN-CONTAINING PHARMACEUTICAL COMPOSITION - The present invention relates to an irbesartan-containing pharmaceutical composition, in particular a tablet thereof, which comprises the active ingredient, a disintegrant with at least one low-substituted hydroxypropyl cellulose.2013-03-07
201300598987-AZONIABICYCLO [2.2.1] HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF - Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetyl-choline receptor-mediated diseases, such as pulmonary diseases, are provided.2013-03-07
20130059899METHODS OF IDENTIFYING MODULATORS OF GPR17 - The present invention is related to a method of determining a test compound's ability to modify the biological activity of a GPR17. Said method comprises, among others, the step of contacting the test compound with a GPR17, or a functional GPR17 fragment in the presence of a suitable amount of a GPR17 agonist of formula I.2013-03-07
20130059900CRYSTAL FORM I OF (S)-4-HYDROXY-2-OXO-1-PYRROLIDINE ACETAMIDE, PREPARING METHOD AND USE THEREOF - A crystal form I of (S)-4-hydroxy-2-oxo-1-pyrrolidine acetamide, or named (S)-oxiracetam, is provided, which is characterized by a powder x-ray diffraction pattern that exhibits data of d-values versus the relative intensities as: 7.075(M), 5.355(S), 5.092(S), 4.590(M), 4.325(M), 4.259(S), 4.041(VS), 3.808(M), 3.542(M), 3.445(M), 3.393(M), 2.972(M), 2.914(S). A method for preparing a crystal form I of (S)-oxiracetam is also provided, which includes preparing the crude product and crystallizing A use of the crystal form I of (S)-oxiracetam in the manufacture of a medicament for preventing and treating memory dysfunction is also provided. Accordingly, the crystal form I of (S)-oxiracetam prepared by the method has high purity of more than 99.3% based on the percentages of the mass, with better efficacy than (S)-oxiracetam for preventing or treating memory dysfunction. Concerning the way of charging materials, adding inorganic base only a few times is simpler and more beneficial to industrial manufacturing and application.2013-03-07
20130059901Pre-MRNA Trans-Splicing Molecule (RTM) Molecules and Their Uses - The present invention relates to specific and markedly improved pre-mRNA trans-splicing molecule (RTM) molecules which are designed to correct specific genes expressed within cells to be targeted, and which are associated with epidermolysis bullosa, cystic fibrosis, pachyonychia congenital, and psoriasis or neurodermitis, as well as cancers of the skin. In particular, the RTMs of the present invention are genetically engineered to interact with a specific target pre-mRNA expressed in cells to be targeted so as to result in correction of genetic defects or reprogramming of gene expression responsible for a variety of different skin disorders.2013-03-07
20130059902METHODS AND COMPOSITIONS USEFUL IN TREATMENT OF DISEASES OR CONDITIONS RELATED TO REPEAT EXPANSION - The present invention is drawn to chemically-modified oligomers that are complementary to, and capable of hybridizing within the repeat region of CAG, CUG, or CCUG nucleotide repeat-containing RNAs (NRRs).2013-03-07
20130059903Compositions and Methods for Characterizing Breast Cancer - The invention provides compositions and methods for characterizing breast cancer stem In particular, the invention provides for the identification of cells expressing Twist and CD44 that express little or virtually undetectable levels of CD24 (i.e. a Twist2013-03-07
20130059904METHODS, AGENTS, AND COMPOUND SCREENING ASSAYS FOR INDUCING DIFFERENTIATION OF UNDIFFERENTIATED MAMMALIAN CELLS INTO OSTEOBLASTS - The present invention relates to methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts. The invention thus provides a method, comprising contacting a compound with a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID No: 194-309; and measuring a compound-polypeptide property related to the differentiation of said cells. The invention further relates to a bone formation enhancing pharmaceutical composition, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean bone density in a subject. Furthermore, the invention relates to a method for the in vitro production of bone tissue.2013-03-07
20130059905Method of Gene Transfer for the Treatment of Recessive Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) - The present invention concerns a method for the treatment of recessive Catecholaminergic Polymorphic Ventricular Tachycardia comprising delivering a gene into a cardiac cell.2013-03-07
20130059906METHODS AND COMPOSITIONS FOR INFLUENCING TUMORS USING MICRORNA-185 AS A TUMOR SUPPRESSOR - The present invention is directed to the use of microRNA-185 (miR-185) as a tumor suppressor. Embodiments of the invention are directed to the use of miR-185 to modulate the expression of tumor-causing genes and to treat subjects.2013-03-07
20130059907WOGONIN-CONTAINING PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER STEM CELLS GROWTH AND APPLICATION THEREOF - A pharmaceutical composition for inhibiting cancer stem cells growth or carcinoma metastasis and an application thereof are disclosed. The pharmaceutical composition includes: a wogonin compound; and a pharmaceutically acceptable carrier. The application is the use of the wogonin compound to manufacture a medicament for inhibiting cancer stem cells growth or carcinoma metastasis.2013-03-07
20130059908SULFONAMIDES FOR THE PREVENTION OF DIABETES - The use of sulfonamides of formula (I) wherein R and R2013-03-07
20130059909Cinnamaldehyde-Allicin Formulations and Methods of Their Use - The invention is directed to emulsifiable oil suspension concentrate formulations containing cinnamaldehyde (cinnamic aldehyde) and allicin that are effective in protecting plants from pests, especially nematodes, and methods of their use.2013-03-07
20130059910CONJUGATES COMPRISING A GABA- OR GLYCINE COMPOUND, PHARMACEUTICAL COMPOSITIONS AND COMBINATIONS THEREOF AS WELL AS THEIR USE IN TREATING CNS DISORDERS - A novel use of conjugates of psychotropic drugs (e.g., antidepressants or anti-epileptic drugs) and organic acids such as GABA in the treatment of pain is disclosed. A novel GABA conjugate and uses thereof is also disclosed.2013-03-07
20130059911POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF - There are provided various polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds can be useful as cancer chemopreventive agents, cancer treating agent, inhibiting tumor growth or cell proliferation, reducing tumor growth or as radioenhencers for radiotherapy of cancer.2013-03-07
20130059912NITRATED-FATTY ACIDS MODULATION OF TYPE II DIABETES - Nitro oleic acid and related metabolites are agonists of PPAR-γ. Surprisingly, nitro oleic acid is a more potent agonist of PPAR-γ, relative to nitro linoleic acid. Thus, nitro oleic acid and its metabolites, as well as their pharmaceutically acceptable salts and prodrug forms, are candidate therapeutics for the treatment of type-2 diabetes, which results from insulin resistance accompanying the improper functioning of PPAR-γ.2013-03-07
20130059913COMPOSITION FOR AMELIORATION OF HYPOALBUMINEMIA - The present invention is directed to a composition for ameliorating hypoalbuminemia containing a branched-chain amino acid(s) as an active ingredient(s), wherein the composition contains leucine and/or isoleucine as the active ingredient(s) and does not contain valine. As the above branched-chain amino acid(s), leucine and isoleucine are preferably contained. The mass ratio of leucine to isoleucine described above is preferably from 0.1 to 10. As the above branched-chain amino acid(s), either leucine or isoleucine alone may be contained. The present invention is suitably used as an infusion formulation, an oral formulation or a food or drink.2013-03-07
20130059915TREATMENT OF PAIN WITH TOPICAL DICLOFENAC - The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.2013-03-07
20130059916BIGUANIDE COMPOUNDS AND ITS USE FOR TREATING CANCER - The invention relates to a compound of formula (I), wherein the radicals R2013-03-07
20130059917MODIFIED RELEASE DOSAGE FORM COMPRISING DESVENLAFAXINE OR SALTS THEREOF - The present invention refers to a modified release pharmaceutical composition comprising desvenlafaxine or salts thereof, a release rate modifying system that controls the release of active agent(s) in both acidic and basic environments. A process of making and method of using the above-described composition is also disclosed.2013-03-07
20130059918Throat irritation relief beverage - A composition beverage and method for relieving a symptom of a sore throat of a user. The composition comprises an aqueous base and an effective amount of a throat soreness relieving agent. The relieving agent may comprise between 0.001% w/v and 0.02% w/v of menthol. The beverage comprises a water base and including between 0.001% w/v and 0.02% w/v of a throat soreness relieving agent. The method comprises the administration of a safe and effective amount of a composition comprising an aqueous base and an effective amount of a throat soreness relieving agent.2013-03-07
20130059919Therapeutic Compounds - A (−)-stereoisomer of formula (I): [insert formula (I) wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful as an anesthetic.2013-03-07
20130059920HYDROXYTYROSOL BENEFITS MUSCLE DIFFERENTIATION AND MUSCLE CONTRACTION AND RELAXATION - This invention is related to the use of hydroxytyrosol (“HT”), or an olive juice extract containing hydroxytyrosol as an agent to improve muscle differentiation and thus improve or maintain the body's adaptation to exercise. It is also related to the use of hydroxytyrosol (“HT”), or an olive juice extract containing hydroxytyrosol as an agent to improve calcium signaling and to improve skeletal muscle contraction and relaxation. It also relates to pharmaceutical and nutraceutical compositions useful for conditions characterized by altered muscle differentiation especially under inflammatory conditions, such as delayed onset muscle soreness subsequent to strenuous exercise or sarcopenia.2013-03-07
20130059921USE OF ESSENTIAL OIL OF OREGANO AND OF ROSEWOOD, OR CONSTITUENTS THEREOF, IN THE THERAPEUTIC TREATMENT OF KERATOSES - The present invention concerns various compositions comprising the essential oil of 2013-03-07
20130059922ANTI-TUMOR PLANT-MEDICAMENT SUSTAINED-RELEASE TABLET OF ELEMENE - Disclosed is an anti-tumor plant-medicament sustained-release tablet of elemene which comprises an elemene as an active component and is prepared by formulation of the elemene, a sustained-release agent, a bulking agent, a disintegrating agent, a binder and a lubricant, each component above-mentioned being in the following weight composition: the elemene 10%-15%, the sustained-release agent 3%-15%, the bulking agent 45%-70%, the disintegrating agent 3%-8%, the binder 1%-10%, and the lubricant 1%-8%. The sustained-release tablet of elemene provided in the invention has properties of expansion and adhesion, which in turn enables extending the retention time of the drug on upper and middle sections of the gastrointestinal tract. Therefore, the tablet may be taken b.i.d.×3, in order to attain reduction in fluctuation of the plasma concentration, maintain effective plasma concentration for a longer period, and reduce the irritation on the gastrointestinal tract. The skeleton-type sustained- and controlled-release formulation has advantages of low cost, easy control, and easy industrialized production.2013-03-07
20130059923Therapeutic Foam - A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.2013-03-07
20130059924PHOTOSTABILISERS - The present invention relates to the use of specific aldehydes or ketones of the formula I as photostabiliser for at least one compound to be stabilised. The invention furthermore relates to a method for the photostabilisation of a second compound by a compound of the formula I and to compositions comprising at least one compound of the formula I of this type.2013-03-07
20130059925Biodegradable Polymeric Hydrogel Composition - A biodegradable polymeric hydrogel composition including a component A and component B forming a β-aminoester linkage such that the linkage results in gelation, wherein component A is water soluble polymer containing acrylate functionality and component B is a water soluble amine functionality useful for medical applications such as such as drug delivery, tissue engineering, and biomaterials and method of preparation thereof.2013-03-07
20130059926METHODS FOR PRODUCING BIOCOMPATIBLE MATERIALS - A method for producing polymerisable solution which comprises dissolving an ethylenically unsaturated zwitterionic monomer in a co-monomer system comprising a functionalised ethylenically unsaturated monomer in which the zwitterionic monomer is soluble, a siloxane group-containing monomer or macromer, and a crosslinking agent is disclosed. The polymerisable solution is biocompatible and can be used to produce polymers and articles such as contact lenses.2013-03-07
20130059927Emulsions of Polyisobutenes, Substance and Process - The present invention is directed to stable emulsions comprising polyolefins, in particular polyisobutene, the process to obtain said emulsions and the use of said emulsions.2013-03-07
20130059928METHOD FOR PREPARING ALKALINE HYDROLYSATES OF PLANT PROTEINS - A method for preparing alkaline hydrolysates of plant proteins, which includes the following steps: 1) preparing a suspension of proteins selected from the group consisting of pea proteins, potato proteins and maize proteins, at a dry matter content of between 10 and 15%; 2) adjusting the pH, with stirring, to a value between 9.5 and 10.5 using, as the only alkaline agent, one or more alkali metal hydroxides selected from the group consisting of sodium hydroxide and potassium hydroxide; 3) heating the resulting suspension at a temperature between 70 and 80° C., for 4 to 6 hours; 4) neutralizing said heated suspension using an inorganic acid, preferably hydrochloric acid; 5) drying the neutralized suspension so as to obtain the alkaline hydrolysate.2013-03-07
20130059929MICROBIOLOGICALLY STABLE, EASILY APPLICABLE PREPARATIONS - Cosmetic or dermatological preparations show improved sensory properties and sufficient microbiological stability due to the addition of benzethonium chloride, methylisothiazolinone, piroctone olamine and/or lauroyl ethyl arginate, the cosmetic or dermatological preparations not comprising any other preservatives, and are especially free of parabens and/or phenoxyethanol.2013-03-07
20130059930DIAGNOSTIC METHOD - The invention provides a method of detecting a subject suffering from, or at risk of suffering from, bladder cancer the method comprising 2013-03-07
20130059931ACTIVATION INDUCED DEAMINASE (AID) - The invention is directed to a cell comprising a nucleic acid encoding an Activation Induced Deaminase (AID) polypeptide, a fusion protein comprising an AID polypeptide, and methods of using a nucleic acid encoding an AID polypeptide.2013-03-07
20130059932SURFACE MODIFIED POROUS POLYMERS FOR ENHANCED CELL GROWTH - A process for surface modification of polymer that enhances cell growth as well as inhibits growth of microorganisms is disclosed.2013-03-07
20130059933EXPANDABLE THERMALLY-STABLE STYRENE COPOLYMERS - A process for producing an expandable pelletized polymeric material which comprises: 2013-03-07
20130059934POLYURETHANE FOAM AND RESIN COMPOSITION - A polyurethane foam and a resin composition that may be used to form the polyurethane foam are provided. The resin composition includes a first polyol based upon ethylene diamine and having about 100% ethylene oxide capping and present in an amount of from about 0.3 to about 15 parts by weight based on 100 parts by weight of the resin composition, a second polyol, and a physical blowing agent having at least 4 carbon atoms. The polyurethane foam includes the reaction product of an isocyanate component and the resin composition comprising the first and second polyol, in the presence of the physical blowing agent. A method of forming the polyurethane foam on a substrate combines the isocyanate component and the resin composition to form a reaction mixture. The reaction mixture is applied onto the substrate to form the polyurethane foam.2013-03-07
20130059935POLYURETHANE WITH IMPROVED ABRASION RESISTANCE, THE METHOD FOR PREPARING THE SAME AND USE THEREOF - The present invention pertains to a polyurethane with improved abrasion resistance. The reactive component for preparing the polyurethane includes a polybutadiene, wherein the polybutadiene comprises 1,2-butene structure unit, 2,3-(cis) butene structure unit and 2,3-(trans) butene structure unit, wherein the amount of the 2,3-(trans) butene structure unit is more than the amount of the 2,3-(cis) butene structure unit. The polyurethane presented in this invention possesses improved abrasion resistance and good surface quality.2013-03-07
20130059936POLYOXYALKYLENE POLYOL, POLYMER-DISPERSED POLYOL, FLEXIBLE POLYURETHANE FOAM AND PRODUCTION PROCESS THEREOF - To provide a process for producing a polyoxyalkylene polyol having a high primary hydroxylation rate of the terminal hydroxyl groups, in spite of a low degree of total unsaturation and a low content of oxyethylene groups.2013-03-07
20130059937SUPER-SOFT THERMOPLASTIC ELASTOMERS - A thermoplastic elastomer (TPE) compound is disclosed which has very low hardness by virtue of the use of a combination of porous styrene block copolymer thermoplastic elastomer of a molecular weight greater than 200,000 and plasticizer oil of a molecular weight less than 400 present in an amount between 85 and 91 weight percent. Super-soft extruded or molded plastic articles can be formed from pellets of the compound, with a resulting Shore OOO Hardness of between 45 and 60. Molded articles can be prepared using hot melt adhesive dispensing units.2013-03-07
20130059938EXTRUSION EXPANSION OF LOW MOLECULAR WEIGHT POLYALKYLENE TEREPHTHALATE FOR PRODUCTION OF EXPANDED BEADS - An extrusion expansion of low molecular weight polyalkylene terephthalates having an IV of below 1.0 dl/g to produce gas-charged beads is disclosed. The process includes an extrusion expanding of the resins and an underwater pelletizing of the melt threads. The obtained beads show a composite structure and are characterized by an IV of 0.69 dl/g or more and a melt viscosity η2013-03-07
20130059939METHOD OF FOAM MOLDING OF RESIN REINFORCED WITH FLAT GLASS FIBERS - Provided is a method for producing glass-fiber-reinforced molded resin foam which retains intact material properties inherent in glass-fiber-reinforced molded resins, has a finely and evenly foamed state, and has excellent mechanical strength, and which can be reduced in weight. The method for producing glass-fiber-reinforced molded resin foam comprises subjecting a resin, flat glass fibers, and a blowing agent to injection molding.2013-03-07
20130059940POLYMERIC PHOTOINITIATORS - A polyalkylether photoinitiator of the general formula I, R2013-03-07
20130059941METHOD OF SURFACE TREATING INORGANIC OXIDE PARTICLES, HARDENABLE DENTAL COMPOSITIONS, SURFACE TREATED PARTICLES, AND SURFACE TREATMENT COMPOUNDS - Presently described are methods of surface treating inorganic oxide particles, hardenable (e.g. dental) compositions comprising a polymerizable resin composition and surface treated particles, as well as surface treated (e.g. nanocluster) inorganic oxide particles, and silane surface treatment compounds. In one embodiment, the method comprises forming a surface treatment compound by reacting a first functional group of a (meth)acrylate monomer having a molecular weight of at least 350 g/mole with a second functional group of a silane compound wherein the first and second functional group react to form a covalent bond; and combining the surface treatment compound with inorganic oxide particles.2013-03-07
20130059942CURABLE POWDER COATING COMPOSITION, AND CURED PRODUCT OF SAME - Disclosed is an epoxy or epoxy-polyester curable powder coating composition which can form a favorable cured coating film excellent in adhesion and solvent resistance and is excellent in storage stability. The curable powder coating composition of the present invention contains the following component (A) and component (B): (A) an epoxy resin or an epoxy-polyester hybrid resin; and (B) a clathrate complex which contains (b1) at least one selected from the group consisting of a carboxylic acid compound and a tetrakisphenol compound represented by the following formula (I), and (b2) at least one selected from compounds represented by formula (II). The carboxylic acid compound preferably includes an aromatic carboxylic acid.2013-03-07
20130059943Halogen-Free, Flame Retardant Composition Comprising Crosslinked Silane-g-EVA - Halogen-free, flame retardant compositions comprising in weight percent based on the weight of the composition: A. 20 to 60% TPU/Si-g-EVA polymer blend in which the Si-g-EVA is crosslinked, B. 1 to 25% organic phosphate ester, C. 30 to 60% metal hydrate, and D. 0.1 to 10% epoxidized novolac. Optionally, the compositions further comprise in weight percent based on the weight of the composition, one or more of: E. 0.01 to 0.5% anti-dripping agent, F. 0.1 to 2% additive; and G. 0.1 to 5% filler.2013-03-07
20130059944RESIN COMPOSITION CONTAINING ULTRAFINE SILVER PARTICLES - [Problems] To provide a resin composition containing ultrafine silver particles and having excellent antibacterial property as well as excellent deodorizing power against both the nitrogen type smelling components and the sulfur-containing smelling components.2013-03-07
20130059945CURABLE COMPOSITIONS - A curable divinylarene dioxide resin composition having a stoichiometric excess of divinylarene dioxides cured with amines, anhydrides, or polyphenols. The curable divinylarene dioxide resin composition includes (a) a stoichiometric excess of at least one divinylarene dioxide, (b) a co-reactive curing agent, and a catalyst. A process for making the above curable divinylarene dioxide resin composition; and a cured divinylarene dioxide resin composition made therefrom are also disclosed. The curable divinylarene dioxide resin composition has a longer pot life prior to cure and produces a thermoset having a higher heat resistance after cure than analogous prior art compositions made using stoichiometric compositions. The curable compositions of the present invention are advantageously useful as thermoset materials, coatings, composites, and adhesives.2013-03-07
20130059946BIOCOMPATIBLE POLYMER NANOPARTICLE COATING COMPOSITION AND METHOD OF PRODUCTION THEREOF - Biocompatible polymeric coating compositions having nanoscale surface roughness and methods of forming such coatings are described. A polymeric biocompatible coating may be produced using a powder coating method, where one or more thermosetting polymer resins and one or more biocompatible materials are mixed and extruded, ground into microscale particles, and mixed with nanoparticles to form a dry powder mixture that may be coated onto a substrate according to a powder coating method. Alternatively, the thermosetting polymeric resin can be first extruded and ground into microscale particles, and then mixed with the biocompatible materials in particular form of nanoscale to microscale in size, and then further mixed with nanoparticles to form a dry powder mixture for coating. Bioactive materials may also be selectively added into the polymeric coating in a similar way as the biocompatible materials, either before or after the extrusion, to form a bioactive polymeric coating.2013-03-07
20130059947CARBON NANOTUBE-REINFORCED NANOCOMPOSITES - Carbon nanotubes (CNTs) are so long that they cannot be penetrated inbetween carbon fibers during a prepreg preparation process, and are shortened in order for them not to be filtered out by the carbon fibers. This results in a huge improvement of the mechanical properties (flexural strength and flexural modulus) compared with neat epoxy.2013-03-07
20130059948MOISTURE-CURABLE SEALING COMPOSITION AND SEALING COMPOSITION SHEET - A moisture-curable sealing composition contains a carboxyl group-containing polymer having a carboxyl group, a plasticizer, and a metal oxide-containing component containing a metal oxide and/or a metal carbonate.2013-03-07
20130059949PREFLOCCULATION OF FILLERS USED IN PAPERMAKING - A method of preparing a stable dispersion of flocculated filler particles for use in papermaking processes comprises use of microparticle prior to, simultaneous to, and/or after addition of a first flocculating agent to an aqueous dispersion of filler particles, followed by addition of a second flocculating agent to the dispersion and further optional shearing of the resultant filler flocs to the desired particle size resulting in shear resistant filler flocs with a defined and controllable size distribution. In addition, a neutralizing coagulant can be added to the dispersion to partially or completely neutralize the charge of the filler before the microparticle and/or the first flocculating agent is added.2013-03-07
20130059950FLOTATION DEVICE REPAIR COMPOSITION AND METHOD - A flotation device temporary repair composition comprising a wax and a metal silicate. Further ingredients may include mineral oil, elastomeric polymers, pigment agents and aroma agents. The repair composition is suitable for repairing a flotation device, such as a surfboard, by simple application into the damaged area to form an instant watertight seal, without the need for curing, and can be removed by hand at a later date to allow more permanent repair.2013-03-07
20130059951HIGH HEAT-RESISTANT POLYGERMANE COMPOUND WITH SULFUR-CONTAINING ORGANIC GROUP - There is provided a polygermane compound forming a film having a high refractive index and thermal stability, and containing a sulfur atom-containing organic group as a group bonded to a germanium atom. A polygermane compound comprising a sulfur atom-containing organic group as a group bonded to a germanium atom, in which the sulfur atom-containing organic group is a group of Formula [1]:2013-03-07
20130059952PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS - The invention relates to compounds of the group of so-called sterically hindered amines (HALS) which are substituted by phospho groups. The invention also relates to flame retardant compositions wherein these compounds are added to the polymer substrate.2013-03-07
20130059953NOVEL POLYTHIOPHENE DISPERSIONS - A process for the preparation of dispersions or solutions comprising polythiophene2013-03-07
20130059954GLUE STICKS FORMULATED WITH ACRYLIC DISPERSIONS - A glue stick formulation that includes at least one acrylic dispersion; at least one solvent; at least one defoamer; at least one fatty acid; at least one caustic solution; at least one processing oil; and at least one adhesion promoter. At least one color indicator and at least one organic amine may also be included in some versions of this formulation.2013-03-07
20130059955Halogen-Free, Flame Retardant TPU Composite - Halogen-free TPU compositions comprise in weight percent based on the weight of the composition: A. 1 to 99% thermoplastic polyurethane (TPU), B. 1 to 50% tris(2-butoxyethyl)phosphate (TBEP), C. 1 to 70% metal hydrate, and D. 1 to 70% organic phosphate ester other than tris(2-butoxyethyl)phosphate. These compositions exhibit better smoke suppression as compared with conventional organic phosphate flame retardant TPU compositions such as those based on resorcinol bis(diphenyl phosphate) (RDP) and bisphenol-A bis(diphenyl phosphate) (BPADP) in the absence of TBEP.2013-03-07
20130059956FLAME RETARDANT POLYOLEFIN COMPOSITION - There is provided herein a polyolefin polymer composition comprising a polyolefin polymer and a metal salt of alkyl alkylphosphonic acid of general formula (I) where X is a metal and R2013-03-07
20130059957POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND CERTAIN THERMAL STABILIZERS, AND/OR REACTION PRODUCTS THEREOF - One aspect of the invention is polyester compositions containing: 2013-03-07
20130059958CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS - A process of modifying propylene polymers via melt grafting of polyfunctional monomer (PFMs) involving pre-initiative step thereby facilitating perfect absorption of PFMs on polymer matrix and initiate their grafting prior to reactive extrusion without using free radical initiators so that branching can be introduced in propylene polymer matrix. The modified propylene polymers showed enhanced shear sensitivity, increase in molecular weight, broadening of molecular weight distribution and strain hardening.2013-03-07
20130059959ANTIFOAMING AGENT FOR VINYL CHLORIDE RESIN SLURRY - Disclosed is an antifoaming agent for vinyl chloride resin slurry. The agent of the present invention may prevent generation of Fish eyes and deteriorate in production efficiency caused by slurry foams without inhibiting inherent transparency of vinyl chloride resins, in the process of preparing the vinyl chloride resins by polymerizing a monomer mixture containing vinyl chloride as a main component in a polymerization reactor.2013-03-07
20130059960AQUEOUS DISPERSION PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET - The present invention relates to a pressure-sensitive adhesive composition containing: an aqueous solvent, an acrylic polymer dispersed in the aqueous solvent, a polyisocyanate crosslinking agent, and a tertiary amine as a neutralizing agent, in which the composition has a liquid phase with a pH of less than 10.2013-03-07
20130059961PVDF coating composition - A composition comprising at least one vinylidene fluoride (VDF) polymer [polymer (F)]; and inorganic particles at least partially coated with at least one perfluoropolyether block copolymer [polymer (E)] comprising: A) one or more (per)fluoropolyoxyalkylene segment (chain R2013-03-07
20130059962MASTERBATCH PELLET, PRODUCTION METHOD THEREFOR AND POLYAMIDE RESIN COMPOSITION CONTAINING MASTERBATCH PELLET - A masterbatch pellet is provided for obtaining a polyamide resin composition excellent in mechanical strength and heat aging resistance. The masterbatch pellet is obtained by melt-kneading a raw material component containing a thermoplastic resin (A) and a metal oxide (B), wherein a content of the metal oxide (B) is 0.5% by mass or more and a fraction of the metal oxide (B) after the melt kneading is present as an aggregated particle of 5 μm or more in a major axis length. A proportion of the aggregated particle of 5 μm or more in a major axis length in a whole metal oxide after the melt kneading is preferably 30% by mass or less.2013-03-07
20130059963COATING COMPOSITION AND APPLICATIONS THEREOF - A coating composition includes a block copolymer, an adhesive resin, and a solvent for dispersing the block copolymer and the adhesive resin therein. The block copolymer contains at least two vinyl aromatic polymer blocks and at least one partially hydrogenated conjugated diene polymer block, and has a hydrogenation ratio ranging from 10% to 90%.2013-03-07
20130059964PROCESS FOR THE POST-MODIFICATION OF HOMO AND COPOLYMERS PREPARED BY CONTROLLED FREE RADICAL POLYMERIZATION PROCESSES - The instant invention pertains to the preparation of polymers or copolymers wherein in a first step a controlled free radical polymerization process is carried out and in a second step the resulting polymer is modified by transesterification reactions. The final modified polymer or copolymer is useful as a dispersant for pigments. Further aspects of the invention are the thus prepared polymers or copolymers, a pigment concentrate containing the polymer or copolymer and a coating material containing the pigment concentrate.2013-03-07
20130059965TIRE TREAD RUBBER COMPOSITION - A tire tread rubber composition includes: diene rubber containing three kinds of rubber (E-SBR, modified S-SBR, and natural rubber (NR)) in a total amount of 80% by weight or more; and a filler in an amount of 100 to 140 parts by weight based on 100 parts by weight of the diene rubber, the filler containing 70% by weight or more of silica, wherein the diene rubber contains 10 to 25% by weight of the natural rubber, the weight ratio of the three kinds of rubber (E-SBR:modified S-SBR:NR) is 1 to 2:2.5 to 4:1, the styrene content of the E-SBR and the modified S-SBR is 35 to 40% by weight, and the difference between the glass transition temperature of the E-SBR and the glass transition temperature of the modified S-SBR is 10° C. or lower.2013-03-07
20130059966FIBER-REINFORCED RESIN COMPOSITION AND MOLDED BODY THEREOF - Long-fiber-reinforced thermoplastic resin particles and a blend thereof are provided, wherein the opening property of the reinforcing fibers during molding is good, and a molded body exhibiting an excellent appearance and having high mechanical strength is obtained. The particles (A) contain a thermoplastic resin (A2013-03-07
20130059967POLYMER COMPOSITIONS, METHODS OF MAKING THE SAME, AND ARTICLES PREPARED FROM THE SAME - The invention provides a composition comprising a first composition that comprises an ethylene-based polymer and an oil, and wherein the first composition has the following property as determined by small angle x-ray scattering: (L2013-03-07
20130059968PLASTIC COMPOSITION - The plastic composition includes PET and Nylon. The weight percentage of PET is between 20% and 90%. The weight percentage of Nylon is between 5% and 40%.2013-03-07
20130059969DISPERSANT COMPOSITION - The present invention relates to a composition containing a particulate solid, a non-polar organic medium, and a compound obtained/obtainable by reacting an aromatic amine with hydrocarbyl-substituted acylating agent, wherein the hydrocarbyl-substituted acylating agent is selected from the group consisting of an oligomer or polymer from condensation polymerisation of a hydroxy-substituted C2013-03-07
20130059970BIOCOMPATIBLE MATERIAL - Monomers of formula (I) which include a vinyl group, polymers and articles, such as contact lenses, made therefrom, all of which are biocompatible, are described.2013-03-07
20130059971Ordered Architectures in Acrylic Polymers - Polymers having ordered architectures and one or more reactive functional groups incorporated in select blocks or regions of the polymer in particular proportions relative to other regions in the polymer, are described. The polymers are well suited for use in adhesive compositions, and particularly for pressure sensitive adhesive compositions. In addition, various methods for forming the noted polymers and adhesive compositions utilizing the ordered polymers are disclosed.2013-03-07
20130059972METHOD TO FORM AN AQUEOUS DISPERSION OF AN IONOMER - Disclosed is a method for forming an aqueous dispersion of an ionomer composition comprising mixing a solid ionomer composition with water heated to a temperature from about 80 to about 90° C., the solid ionomer composition comprising an ethylene acid copolymer comprising about 18 to about 30 weight % of copolymerized units of acrylic acid or methacrylic acid, based on the total weight of the parent acid copolymer, the acid copolymer having a melt flow rate from about 200 to about 1000 g/10 min., wherein about 50% to about 70% of the total carboxylic acid groups of the copolymer are neutralized to carboxylic acid salts comprising sodium cations.2013-03-07
20130059973POLYISOCYANATE PREPOLYMERS AND THEIR USE - The invention provides polyisocyanate prepolymers, characterised in that they contain polyether carbonate polyols as structural component, their preparation and their use as isocyanate component in 1- and 2-component systems for surface-coating compositions, adhesives and sealing materials.2013-03-07
20130059974PHENOLIC RESIN MOLDING COMPOUND - Provided is a phenolic resin molding compound including (A) a novolac-type phenolic resin including an alkylbenzene-modified novolac-type phenolic resin, (B) a resol-type phenolic resin, (C) hexamethylenetetramine, (D) graphite, and (E) fiber-shaped filler, wherein in regard to the content of each component on the basis of the entirety of the molding compound, a total content of the components (A) to (C) is 30 to 40% by weight, a content of the component (D) is 30 to 50% by weight, and a content of the component (E) is 5 to 20% by weight.2013-03-07
20130059975POLYMERIZABLE IONIC LIQUID COMPRISING AROMATIC CARBOXYLATE ANION - Presently described are polymerizable ionic liquids comprising a cation and an aromatic carboxylate anion; wherein the cation, anion, or both comprise a free-radically polymerizable group. Also described are curable compositions comprising such polymerizable ionic liquids and at least one other free-radically polymerizable monomer, oligomer, or polymer.2013-03-07
20130059976RESIN COMPOSITION FOR HOLLOW BLOW-MOLDED ARTICLE, HOLLOW BLOW-MOLDED ARTICLE, AND METHOD OF PRODUCING THE HOLLOW BLOW-MOLDED ARTICLE - There are provided, according to the present invention, a resin composition for hollow blow-molded article which is obtained in a high productivity on an industrial scale with excellent moldability and drawdown resistance, and the production method thereof, by melting and mixing a polyarylene sulfide resin including a terminal carboxyl group within the resin in an amount of 25 to 45 (μmol/g), and having a non-Newtonian index of 0.90 to 1.15 and also a melt viscosity as measured at 300° C. within the range of 1,000 poise to 3,000 poise and an epoxy group-containing polyolefin so that the proportion of the epoxy group-containing polyolefin is 5 to 30 parts by mass with respect to 100 parts by mass of the polyarylene sulfide resin; and a hollow blow-molded article with excellent mechanical strength, such as the heat resistance and impact resistance, and surface appearance, and the production method thereof.2013-03-07
20130059977THERMOPLASTIC ELASTOMER COMPOSITION - Disclosed is a thermoplastic elastomer composition that will provide little load on the environment and has superior mechanical characteristics, the composition being obtained by melt-kneading 10 to 90 parts of ethylene-α-olefin based copolymer rubber (A), 1 to 50 parts of non-petroleum source-derived thermoplastic resin (B), 0.01 to 20 parts of modified ethylene-based copolymer (C), 1 to 50 parts of propylene-based polymer (D), 0.001 to 5 parts of crosslinking agent (E), and 0 to 50 parts of a mineral oil-based softening agent (F), wherein the amounts of components (A), (B), (D) and (F) are amounts in weight calculated where the total amount of components (A), (B), (D) and (F) is considered to be 100 parts, and the amounts of components (C) and (E) are amounts in weight calculated where the total amount of components (A), (B), (D) and (F) is considered to be 100 parts.2013-03-07
20130059978THERMOPLASTIC ELASTOMER COMPOSITION - Disclosed is a thermoplastic elastomer composition that will provide little load on the environment and has superior mechanical characteristics, the composition being obtained by melt-kneading 10 to 90 parts of ethylene-α-olefin based copolymer rubber (A), 1 to 50 parts of non-petroleum source-derived thermoplastic resin (B), 1 to 50 parts of modified propylene-based copolymer (C), 1 to 50 parts of propylene-based polymer (D), 0.001 to 5 parts of crosslinking agent (E), and 0 to 50 parts of mineral oil-based softening agent (F), wherein the amounts of components (A), (B), (C), (D), and (F) are amounts in weight calculated where the combined amount of components (A), (B), (C), (D) and (F) is considered to be 100 parts by weight, and the amount of component (E) is an amount in weight calculated where the combined amount of components (A), (B), (C), (D), and (F) is considered to be 100 parts by weight.2013-03-07
20130059979Process for Forming Polymer Blends - A method for forming a fiber, the method comprising charging to a reactive extruder a first polymer and a second polymer to form an initial blend, where the first polymer is a propylene-based elastomer including up to 35% by weight ethylene-derived units and a heat of fusion, as determined according to DSC procedures according to ASTM E-793, of less than 80 J/g and a melt temperature of less than 110° C., where the second polymer is a propylene-based polymer having a melt temperature in excess of 110° C. and a heat of fusion in excess of 80 J/g, and introducing the reactive blend to a spinneret to form a fiber or extruding the reacted blend through a plurality of die capillaries to form molten threads or filaments which are attenuated in a gas stream to form meltblown fibers.2013-03-07
20130059980THERMOPLASTIC TRANSPARENT RESIN COMPOSITION - To provide a highly transparent thermoplastic resin composition without requiring, for example, a special molecular design or incorporation of an additive, with the refractive index of the composition being readily controllable.2013-03-07
20130059981THERMOPLASTIC ELASTOMER POLYOLEFIN IN-REACTOR BLENDS AND MOLDED ARTICLES THEREFROM - This invention relates to an in-reactor polymer blend comprising: (a) a first ethylene-containing polymer having a density of greater than 0.90 g/cm2013-03-07
20130059982Hyperbranched Polymers and Methods of Making and Using Same - A composition comprising a polyethylene wherein the composition is enriched in polymer molecules having topological variations by an enrichment factor ω and wherein the composition displays a long chain branching frequency of greater than about 0.5 long chain branches per 1000 total carbon atoms. A composition comprising an isolated Ziegler-catalyzed polyethylene having a long chain branching frequency of greater than about 0.5 long chain branches per 1000 total carbon atoms at the high molecular weight end.2013-03-07
20130059983METHOD OF MANUFACTURING ESTERIFIED SUBSTANCE - According to the invention, a method of manufacturing an esterified substance including a process in which a copolymer is obtained by copolymerizing a 1-alkene having 5 to 80 carbon atoms and maleic anhydride, and a process in which an esterification reaction of the copolymer and an alcohol having 5 to 25 carbon atoms is caused in a presence of trifluoromethanesulfonic acid in order to obtain a reaction mixture containing an esterified substance including at least one repetition unit selected from formulae (c) to (f) is provided, and, in the formulae (c) to (f), R represents an aliphatic hydrocarbon group having 3 to 78 carbon atoms, R2013-03-07
20130059984PREPARATION METHOD OF METAL NANOBELT - This disclosure relates to a method of preparing a metal nanobelt. According to the method, a metal nanobelt having various applicabilities, for example, capable of easily forming a conductive film or a conductive pattern with excellent conductivity, may be easily prepared by a simple process at room temperature and atmospheric pressure. The method comprises reacting a conductive polymer and a metal salt.2013-03-07
20130059985METHOD OF MANUFACTURING POLYBENZOXAZOLE PRECURSOR - The present invention provides a method for producing a polybenzoxazole precursor having reduced contents of residual aprotic polar solvent and residual halogen without discharging a large amount of waste water during purification. The present invention specifically relates to a method for producing a polybenzoxazole precursor, which comprises synthesizing a polybenzoxazole precursor in an aprotic polar solvent, adding and mixing water and a water-insoluble solvent with the resulting polybenzoxazole precursor solution to still stand the solution, and then separating a water layer from the solution to reduce a content of impurities remaining in the polybenzoxazole precursor.2013-03-07
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