| 10th week of 2015 patent applcation highlights part 67 |
| Patent application number | Title | Published |
|---|
| 20150065653 | CATALYST MASTERBATCH - The present invention relates to a catalyst masterbatch for cross-linking a polyolefin comprising cross-linkable silicon-containing groups comprising
| 2015-03-05 |
| 20150065654 | Tribologically Modified Polyoxymethylene - Disclosed is a tribologically modified molding composition, a method for the manufacturing of molded article by melt mixing said molding composition, molded article obtainable therefrom as well as the use of the molding composition for the manufacturing of molded parts used in the automotive industry or for housings, latches, window winding systems, wiper systems, pulleys, sun roof systems, seat adjustments, levers, gears, claws, pivot housings, wiper arms, brackets or seat rails bearings, gears, cams, rollers, sliding elements such as sliding plates, conveyer belt parts such as chain elements and links, castors, fasteners, levers, conveyor system wear strips and guard rails. | 2015-03-05 |
| 20150065655 | Dicyclopentadiene Based Resin Compositions and Articles Manufactured Therefrom - A composition including at least one elastomer, and a hydrocarbon polymer additive having a dicyclopentadiene, cyclopentadiene, and methylcyclopentadiene derived content of about 40 wt % to about 80 wt % of the total weight of the hydrocarbon polymer additive, a weight average molecular weight of about 100 g/mole to about 800 g/mole, and a softening point of about 110° C. to about 150° C. as determined in accordance with ASTM D6090. | 2015-03-05 |
| 20150065656 | Ethylene-Based Polymers and Articles Made Therefrom - Polymer compositions that include an ethylene-based polymer and a broad molecular weight distribution propylene-based polymer having a melt strength of 20.0 cN to 200.0 cN; and optionally, a propylene-based elastomer are described. The invention also includes articles, such as films, produced from such compositions and methods of making such compositions and methods of improving melt strength. | 2015-03-05 |
| 20150065657 | ROTOMOLDING RESIN - Resins suitable for rotomolded articles comprise a bimodal polyethylene copolymer comprising from 0.1 to 5 weight % of one or more C | 2015-03-05 |
| 20150065658 | NON-AQUEOUS DISPERSANT, COLOR MATERIAL DISPERSION LIQUID AND METHOD FOR PRODUCING THE SAME, COLOR RESIN COMPOSITION AND METHOD FOR PRODUCING THE SAME, COLOR FILTER, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC LIGHT-EMITTING DISPLAY DEVICE - The present invention is to provide: a non-aqueous dispersant which is excellent in dispersibility and dispersion stability and able to form a resin layer with excellent hydrolysis resistance; a color material dispersion liquid containing the non-aqueous dispersant; and a color resin composition containing the non-aqueous dispersant. | 2015-03-05 |
| 20150065659 | POLYMERIC STRUCTURE - The invention features a method of creating a polymer brush bearing covalently bound polymeric side chains, comprising the steps of: (a) deposition, onto a substrate, of a halogen containing initiator film or a precursor which is derivatized into a halogen containing initiator film; (b) surface ATRP growth, from the halogen containing initiator film formed in step (a), of a polymeric brush backbone incorporating side groups; (c) growth, from the polymeric brush backbone formed in step (b), of polymeric side chains on the polymeric brush backbone, to form a polymer brush in which the polymeric side chains constitute the bristles of the brush. | 2015-03-05 |
| 20150065660 | METHODS FOR SEPARATING MIXTURES OF COMPOUNDS - The invention provides methods and membranes for separating mixtures of two or more compounds such as fatty acids or fatty acid esters. | 2015-03-05 |
| 20150065661 | BLEND OF POLY(PHENYLENE ETHER) PARTICLES AND POLYOXYMETHYLENE, ARTICLE THEREOF, AND METHOD OF PREPARATION - A composition contains (a) 1 to 40 weight percent of poly(phenylene ether) particles having a mean particle size of 1 to 40 micrometers; and (b) 60 to 99 weight percent of a polyoxymethylene; wherein polystyrene is absent from the poly(phenylene ether) particles; wherein the composition comprises less than 0.1 volume percent, based on the total volume of the composition, of particulate metals, metalloids, oxides thereof, and combinations thereof, wherein the metals and metalloids are selected from iron, copper, aluminum, magnesium, lead, zinc, tin, chromium, nickel, tungsten, silicon, gold, silver, platinum, and alloys thereof. The poly(phenylene ether) particles reduce the density and increase the char yield of the polyoxymethylene. When the composition is prepared at a temperature below the glass transition temperature of the poly(phenylene ether), increased flexural strength can also be obtained. The composition is useful as a molding composition for a variety of articles. | 2015-03-05 |
| 20150065662 | CURING AGENT COMPOSITIONS FOR CONDENSATION-CROSSLINKING RTV-2 SYSTEMS - Hardener compositions for condensation-crosslinking RTV-2 systems free of organotin compounds contain a catalyst selected from among compounds of titanium, cerium, zirconium, molybdenum, manganese, copper, zinc, bismuth, lithium, strontium, or boron, and at least one aminoalkyl alcohol reinforcing the effectiveness of the catalyst. | 2015-03-05 |
| 20150065663 | CURABLE COMPOSITION, CURED PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION - The present invention is: a curable composition comprising a component (A) and a component (B) in a mass ratio (component (A):component (B)) of 100:0.3 to 100:40, the component (A) being a silane compound copolymer that is represented by a formula (a-1), and has a weight average molecular weight of 800 to 30,000, | 2015-03-05 |
| 20150065664 | GRANULAR POLYARYLENE SULFIDE AND PROCESS FOR MANUFACTURING THE SAME - A granular polyarylene sulfide; (i) the granular polyarylene sulfide containing an —S— substituent at the terminal, the substituent being formed by cleavage of a disulfide compound; (ii) the granular polyarylene sulfide being an oversize fraction after sifting with a sieve having a mesh size of at least 38 μm; (iii) the granular polyarylene sulfide having a halogen content of at most 1,500 ppm; and (iv) the granular polyarylene sulfide being a granular polyarylene sulfide having a melt viscosity of 3 to 100 Pa·s when measured under conditions at a temperature of 310° C. and a shear rate of 1,200 sec | 2015-03-05 |
| 20150065665 | PROCESS - The present invention relates to the treatment and recycle of effluent streams from a polymerisation process, and in particular provides a polymerisation process comprising the steps of: 1) Polymerising a monomer and a comonomer in a polymerisation reaction, 2) Withdrawing an effluent stream comprising solid polymer and a mixture comprising unreacted monomer and unreacted comonomer, and passing the effluent to a high pressure recovery system comprising a. a high pressure separation step for separating a vapour comprising unreacted monomer and unreacted comonomer from said solids, and b. a high pressure recycle system for recycling a portion of the vapour to the polymerisation reaction, 3) Passing the solids from the high pressure recovery system to a low pressure recovery system comprising a. a low pressure separation step for separating further unreacted monomer and unreacted comonomer from said solids, and b. a low pressure recycle system for recycling at least a portion of the unreacted monomer and unreacted comonomer to the polymerisation reaction, characterised in that a portion of the vapour separated in step 2(a) is passed to the low pressure recovery system. | 2015-03-05 |
| 20150065666 | Process for Preparing Polyolefins - The present invention relates to a process of preparing a polyolefin in a loop reactor by introducing anti-fouling agent in by-pass pipes. Also, the invention relates to the use of anti-fouling agent to prevent blockage by feeding the anti-fouling agent into the by-pass pipes of the loop reactor. | 2015-03-05 |
| 20150065667 | SUPPORTED METAL OXIDE DOUBLE ACTIVE CENTER POLYETHYLENE CATALYST, PROCESS FOR PREPARING THE SAME AND USE THEREOF - The present invention relates to a supported hybrid vanadium-chromium-based catalyst, characterized in the catalyst is supported on a porous inorganic carrier and a V active site and a inorganic Cr active site are present on the porous inorganic carrier at the same time. The present invention further relates to a process for producing a supported hybrid vanadium-chromium-based catalyst. The invention also provides the preparation method of the catalyst, titanium or fluorine to compounds, vanadium salt and chromium salt according to the proportion, different methods of sequence and load on the inorganic carrier, after high temperature roasting, still can further add organic metal catalyst promoter prereduction activation treatment on it. The catalyst of the present invention can be used for producing ethylene homopolymers and ethylene/α-olefin copolymers. The hybrid vanadium-chromium-based catalyst can have high activity and produce polyethylene polymers having the properties of broad molecular weight distribution (Part of the products are bimodal distribution) and excellent α-olefin copolymerization characteristic. | 2015-03-05 |
| 20150065668 | Racemo Selective Metallation Process - This invention relates to racemic bridged bis(indenyl)metallocene transition metal compounds, rac-directing metallation reagents and a process to produce the racemic bridged bis(indenyl)metallocene transition metal compounds using the rac-directing metallation regents. | 2015-03-05 |
| 20150065669 | Higher Density Polyolefins With Improved Stress Crack Resistance - Disclosed herein are polymerization processes for the production of olefin polymers. These polymerization processes can employ a catalyst system containing two or three metallocene components, resulting in ethylene-based copolymers that can have a medium density and improved stress crack resistance. | 2015-03-05 |
| 20150065670 | ASYMMETRIC BIFUNCTIONAL SILYL MONOMERS AND PARTICLES THEREOF AS PRODRUGS AND DELIVERY VEHICLES FOR PHARMACEUTICAL, CHEMICAL AND BIOLOGICAL AGENTS - Asymmetric bifunctional silyl (ABS) monomers comprising covalently linked pharmaceutical, chemical and biological agents are described. These agents can also be covalently bound via the silyl group to delivery vehicles for delivering the agents to desired targets or areas. Also described are delivery vehicles which contain ABS monomers comprising covalently linked agents and to vehicles that are covalently linked to the ABS monomers. The silyl modifications described herein can modify properties of the agents and vehicles, thereby providing desired solubility, stability, hydrophobicity and targeting. | 2015-03-05 |
| 20150065671 | ORGANIC SEMICONDUCTOR MATERIAL - A compound represented by the formula (1). A polymer compound comprising the compound. An organic semiconductor material comprising the compound or the polymer compound. An organic semiconductor device comprising an organic layer comprising the organic semiconductor material. An organic transistor comprising a source electrode, a drain electrode, a gate electrode and an active layer, wherein the active layer comprises the organic semiconductor material. | 2015-03-05 |
| 20150065672 | AMPHIPHILIC MACROMOLECULE AND USE THEREOF - Amphiphilic macromolecules having repeating structural units: structural units to adjust molecular weight and molecular weight distribution and charging property effects, high stereo-hindrance structural units, and amphiphilic structural units, and are suitable for fields such as oil field well drilling, well cementation, fracturing, oil gathering and transfer, sewage treatment, sludge treatment and papermaking, etc., and can be used as an oil-displacing agent for enhanced oil production, a heavy oil viscosity reducer, a fracturing fluid, a clay stabilizing agent, a sewage treatment agent, a papermaking retention and drainage aid or a reinforcing agent, etc. | 2015-03-05 |
| 20150065673 | Preparation Of Functional Polymers Using Phosphide Initiators - A method of preparing a polymer, the method comprising: metalating an organophosphine compound in the substantial absence of monomer to form a metalated organophosphine; and introducing the metalated organophosphine to monomer including conjugated diene monomer to form a reactive polymer. | 2015-03-05 |
| 20150065674 | CONTROLLED POLYMERIZATION OF FUNCTIONAL FLUORINATED POLYHEDRAL OLIGOMERIC SILSESQUIOXANE MONOMERS - A polymer comprising polymerized units of norbornene fluoroalkyl polyhedral oligomeric silsesquioxane. According to aspects of the present invention, the polymer may be norbornene fluoroalkyl polyhedral oligomeric silsesquioxane. Still other aspects of the present invention may include a polymerized unit of an alkene chain derived from a cyclic alkene. | 2015-03-05 |
| 20150065675 | POLYURETHANES MADE USING BISMUTH THIOCARBAMATE OR THIOCARBONATE SALTS AS CATALYSTS - Polyisocyanate-based polymers are formed by curing a reaction mixture containing at least one polyisocyanate and at least one isocyanate-reactive compound having at least two isocyanate-reactive groups in the presence of a bismuth mono- or dithiocarbamate or mono- or dithiocarbonate salt. | 2015-03-05 |
| 20150065676 | POLYURETHANE DISPERSANT AND THE METHOD FOR ITS PREPARATION - The present invention is related to a polyurethane dispersant and a preparation method thereof. The polyurethane dispersant is terminated by a nitrogen-containing heterocyclic compound during synthesis. The nitrogen-containing heterocyclic compound is prepared by subjecting anhydride and a compound containing a primary amine and a secondary amine or a hydroxyl or mercapto group to dehydration condensation. The condensed product is the nitrogen-containing heterocyclic compound, containing a reactive hydrogen. The structural formula of the compound containing the primary amine and the secondary amine or hydroxyl or mercapto group is shown as follows: | 2015-03-05 |
| 20150065677 | PROCESS FOR PRODUCING AROMATIC POLYETHER SULFONES - The process for producing aromatic polyether sulfones via reaction of a dichlorodiphenyl sulfone component with a bisphenol component as monomers in the presence of alkali metal carbonate in the melt in the absence of solvents and diluents comprises carrying out the reaction in a mixing kneader which is operated with a shear rate in the range from 5 to 500 s | 2015-03-05 |
| 20150065678 | METHOD FOR THE PRODUCTION OF ALIPHATIC POLYESTERS - The present invention relates to a method for the production of aliphatic polyesters in a two-step method. There are thereby added, in a first step, to a precondensate of an aliphatic dicarboxylic acid or to a mixture of aliphatic dicarboxylic acids and an aliphatic dialcohol or to a mixture of aliphatic dialcohols, further monomeric components, i.e. further aliphatic dicarboxylic acids and also a further aliphatic dialcohol, a polyester prepolymer being obtained. In a further step, polycondensation of the prepolymer obtained in the first step is effected. | 2015-03-05 |
| 20150065679 | MONOMERS BEARING ASSOCIATIVE GROUPS FOR THE SYNTHESIS OF SUPRAMOLECULAR POLYCONDENSATES - The present invention relates to the use of monomers bearing associative groups in order to manufacture a supramolecular polycondensate, to certain of these monomers, to a process for manufacturing a supramolecular polycondensate, to the polycondensate obtained, and also to an article or a composition incorporating same. | 2015-03-05 |
| 20150065680 | FLAKES OF ESTER MIXTURES AND METHODS FOR THEIR PRODUCTION - There is provided flakes of an ester mixture comprising bis-(hydroxyethyl)-terephthalate, dimers, tamers, tetramers, pentamers and higher oligomers of ethane-1,2-diol and terephthalate acid. | 2015-03-05 |
| 20150065681 | Method of Preparing Prepolymer Particle - Disclosed herein is a method of preparing prepolymer particles. The method includes injecting a prepolymer in a solution state by bottom-up type injection to form prepolymer particles by removing a solvent from the prepolymer in a solution state. The method can prepare prepolymer particles, which can be used in solid-state polymerization, using a bottom-up type flash process. | 2015-03-05 |
| 20150065682 | ALIPHATIC POLYESTERS AND COPOLYESTERS DERIVED FROM NATURAL OILS AND THEIR RELATED PHYSICAL PROPERTIES - The synthesis of certain medium and long chain ω-hydroxy esters and certain ω-hydroxy fatty acids is disclosed. Such ω-hydroxy esters and ω-hydroxy fatty acids are derived from natural oils, and their corresponding polymers were obtained by melt polycondensation. Additionally, the present effort investigates the effects of structural and molecular parameters on the thermal and mechanical properties of ω-hydroxy ester based polymers. Additionally, the present effort investigates the co-polymerization of ω-hydroxy ester based polymers. | 2015-03-05 |
| 20150065683 | OPIORPHIN PEPTIDE DERIVATIVES AS POTENT INHIBITORS OF ENKEPHALIN-DEGRADING ECTOPEPTIDASES - The present invention relates to modified opiorphin peptides as new inhibitors of metallo-ectopeptidases. | 2015-03-05 |
| 20150065684 | USE OF SOLUBLE FORMS OF CD83 AND NUCLEIC ACIDS ENCODING THEM FOR THE TREATMENT OR PREVENTION OF DISEASES - The present invention provides for the use of soluble forms of CD83 and nucleic acids encoding them for the treatment of diseases caused by the dysfunction or undesired function of a cellular immune response involving dendritic cells, T cells and/or B cells. The invention moreover provides soluble CD83 molecules specifically suited for said purpose, antibodies against said specific soluble CD83 proteins and assay methods and kits comprising said antibodies. | 2015-03-05 |
| 20150065685 | LASER-ACTUATED THERAPEUTIC NANOPARTICLES - The invention provides compositions and methods for laser actuated drug delivery. Compositions comprise serum albumin based particles conjugated with therapeutic agents which cab become bioavailable upon actuation of the particles by light, e.g. low power laser. | 2015-03-05 |
| 20150065686 | METHOD FOR MAKING A FIBRE COMPRISING NATURAL FIBRE NANOPARTICLES - A method for making natural fibre products comprising embrittling natural fibres and breaking the embrittled fibres into nanoparticles, forming a suspension of the fibre nanoparticles in a spinnable liquid, and spinning fibre from the suspension. The method may be used to make fibres having the dimensions and properties of cashmere. | 2015-03-05 |
| 20150065687 | ALBUMIN VARIANTS - The present invention relates to variants of a parent albumin, the variants having altered plasma half-life compared with the parent albumin. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. | 2015-03-05 |
| 20150065688 | SURFACES HAVING NANOPARTICULATE LAYERS AND ASSEMBLY AND USE THEREOF - A method for generating layered structures is disclosed. The method comprises reacting an azide-functionalized material with an alkyne-functionalized material, one of which can be a nanoparticle or a microparticle and the other can be a substrate or another nanoparticle or microparticle. The method also includes generating layered structures having multiple layers which can be built up in multiple azide-alkyne reaction steps. | 2015-03-05 |
| 20150065689 | SINGLE STEP FRACTIONATION METHOD - Single step method of enriching highly sialylated variant/s of a protein by use of a strong ion exchange chromatography support and a pH gradient in absence of any salt gradient. | 2015-03-05 |
| 20150065690 | MODIFIED ANTIBODY REGIONS AND USES THEREOF - The present invention relates to modified Fc regions of antibodies, and uses thereof, such as in antibodies that contain an Fc region of the present invention. | 2015-03-05 |
| 20150065691 | Anti-Cancer Antibodies With Reduced Complement Fixation - The invention provides modified antibodies directed against GD2 that have diminished complement fixation relative to antibody-dependent, cell-mediated cytotoxicity, which is maintained. The modified antibodies of the invention may be used in the treatment of tumors such as neuroblastoma, glioblastoma, melanoma, small-cell lung carcinoma, B-cell lymphoma, renal carcinoma, retinoblastoma, and other cancers of neuroectodermal origin. | 2015-03-05 |
| 20150065692 | GENERATION OF A CANCER-SPECIFIC IMMUNE RESPONSE TOWARD MUC1 AND CANCER SPECIFIC MUC1 ANTIBODIES - The present invention provides a method for inducing a cancer specific immune response against MUC1 using an immunogenic glycopeptide. Other aspects of the invention are a pharmaceutical composition comprising the immunogenic glycopeptide and a cancer vaccine comprising the immunogenic glycopeptide. Another aspect is an antibody generated using the immunogenic glycopeptide and the use of said antibody in therapy and diagnosis. | 2015-03-05 |
| 20150065693 | COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF VASCULAR OR CARDIAC VALVULAR CALCIFICATION COMPRISING DIPEPTIDYL PEPTIDASE-4 INHIBITOR - There is provided a composition for prophylaxis or treatment of vascular or valvular calcification including a dipeptidylpeptidase-4 (DPP-4) inhibitor. The DPP-4 according to one exemplary embodiment of the present disclosure is expressed at an increased level when blood vessels and valves are calcified, and the calcification decreases remarkably upon administration of the DPP-4 inhibitor. Therefore, the DPP-4 inhibitor can be useful in treatment or prophylaxis of blood vessels or valves. | 2015-03-05 |
| 20150065694 | Preassembled hybrid nanocluster plasmonic resonator for immunological detection and serotyping of virus and microbes - Here, we describe a preassembled plasmonic resonance nanocluster. One embodiment is used for microbe detection and typing. The metallic nanoparticle acceptors with microbe surface antigen epitope, and quantum dot (QD) donors with Fab antibody, are assembled into an immuno-mediated 3D-oriented complex with enhanced energy transfer and fluorescence quenching. The coherent plasmonic resonance between the metal and QD nanoparticles is exploited to achieve improved donor-acceptor resonance within the nanocluster, which in the presence of microbial particles is disassembled in a highly specific manner. The nanocluster provides high detection specificity and sensitivity of the microbes, with a sensitivity limit down to 1-100 particles per microliter and to attomolar levels of a surface antigen epitope. A few specific examples of the plasmonic resonance nanocluster used in microbe detection are disclosed along with ways in which the complex can be easily modified for additional microbes. | 2015-03-05 |
| 20150065695 | Recombinant FSH Including Alpha 2,3- and Alpha 2,6-Sialylation - Preparations including recombinant FSH (rFSH). | 2015-03-05 |
| 20150065696 | APPARATUS AND PROCESS FOR PURIFICATION OF PROTEINS - The invention is directed to an apparatus and method for purifying a protein. The apparatus involves the use of a capture chromatography resin, a depth filter arranged after the capture chromatography resin, and a mixed-mode chromatography resin arranged after the depth filter. The method involves providing a sample containing the protein, processing the sample through a capture chromatography resin, a depth filter, and a mixed-mode chromatography resin. A membrane adsorber or monolith may be substituted for the mixed-mode chromatography column. | 2015-03-05 |
| 20150065697 | Colorant Compounds - Disclosed is a compound of the formula | 2015-03-05 |
| 20150065698 | MICROWAVE ASSISTED CITRUS WASTE BIOREFINERY - There is described a method of isolating one or more of pectin, d-limonene, a flavour compound, a flavonoid, a soluble monosaccharide, a decomposition product of a monosaccharide and cellulose, from citrus material wherein said method comprises the microwave assisted hydrothermal low temperature treatment of citrus material. | 2015-03-05 |
| 20150065699 | GINSENOSIDE C-K POLYMORPHIC COMPOUNDS AND METHOD FOR PREPARING SAME - Provided are several types of ginsenoside polymorphic substances and a method for preparing same. In particular, new crystal form A, crystal form B, crystal form C, crystal form E, crystal form F, crystal form I, crystal form K, crystal form L, crystal form M, crystal form N, and crystal form O are involved. | 2015-03-05 |
| 20150065700 | METHOD FOR PREPARING 3-O-BENZYL-1,2-O-ISOPROPYLIDENE-A-L-FURAN IDOSE - Provided is a method for preparing 3-O-benzyl-1,2-O-isopropylidene-α-L-idofuranose, which comprises: (1) protecting hydroxyl of 3-O-benzyl-1,2-O-isopropylidene-α-D-glucofuranose (III) by benzoyl and methylsulfonyl to obtain 6-O-benzoyl-3-O-benzyl-1,2-O-isopropylidene-5-O-methylsulfonyl-α-D-glucofuranose (V); (2) subjecting compound (V) to a cyclization reaction under an alkaline condition to obtain 5,6-epoxy-3-O-benzyl-1,2-O-isopropylidene-α-L-idofuranose (VI); and (3) subjecting compound (VI) to a ring-opening reaction to obtain 3-O-benzyl-1,2-O-isopropylidene-α-L-idofuranose. | 2015-03-05 |
| 20150065701 | INJECTABLE MONOPHASE HYDROGELS - An injectable monophase hydrogel is provided and is made of a reaction mixture of a high molecular weight hyaluronic acid and a low molecular weight hyaluronic acid. | 2015-03-05 |
| 20150065702 | Synthesis of the Trisaccharide 3-O-Fucosyllactose and Intermediates Thereof - 3-O-Fucosyllactose is made by process which includes the hydrogenolysis of a new compound of the formula 1 wherein R | 2015-03-05 |
| 20150065703 | 7-MEMBERED FUSED HETEROCYCLES AND METHODS OF THEIR SYNTHESIS - Disclosed are a new method for synthesizing 7-membered fused heterocycles and compounds synthesized by the new method. The method involves a dual activation strategy using an N-heterocyclic carbene catalyst as a first Lewis base and another second Lewis base. Compounds synthesized by the disclosed method may include new benzoxopinone compounds, as well as benzoxepane compounds and benzoazepinone compounds that optionally may be derived from the disclosed benzoxopinone compounds. | 2015-03-05 |
| 20150065704 | PROCESS FOR THE PREPARATION AND PURIFICATION OF ESLICARBAZEPINE ACETATE AND INTERMEDIATES THEREOF - The present invention provides a novel process for the preparation of 10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide, commonly known as oxcarbazepine, which is a medicament and a useful intermediate in the preparation of eslicarbazepine acetate. The present invention further provides a process for the preparation and purification of eslicarbazepine acetate. | 2015-03-05 |
| 20150065705 | TRIAZINONE COMPOUND AND T-TYPE CALCIUM CHANNEL INHIBITOR - There is provided a novel triazinone compound that has an excellent T-type voltage-dependent calcium channel inhibitory activity and is specifically useful for treatment of pain. A compound of Formula (I), a tautomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof: | 2015-03-05 |
| 20150065706 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS - The invention relates to (among other things) methods for treatment comprising administering oligomer-containing substituted aromatic triazine compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits one or more advantages over corresponding compounds lacking the oligomer. | 2015-03-05 |
| 20150065707 | CARBOXYLIC ACID TYPE WATER-SOLUBLE SULFUR DYE - The present invention provides a group of water-soluble sulfur dye having carboxyl groups. For the kind of dye, a sulfur dye is first reduced to a leuco compound by sodium sulfide, and the leuco compound reacts with an active compound containing carboxyl groups to obtain a water-soluble sulfur dye containing the carboxyl group. The water-soluble sulfur dye provided by the present invention is applicable to dying of cotton, wool, silk, and leather. Being both water-soluble and carboxyl group reactive, the product has a simple application process and desirable color fastness, thereby having broad application prospects. | 2015-03-05 |
| 20150065708 | COMPOUND JK12A AND PREPARATION THEREOF - The present invention relates to a compound [4-(2-amino-10-methyl-4-oxo-6,7,8,9-tetrahydro-4a,7-cycloimino-pyrimido[4,5-b][1,4]diazepine-5(4H)-yl)benzoyl]-glutamate (JK12A for short) with the structure in Formula I. The present invention also relates to the crystal form and salt of the compound JK12A, and preparation method and applications thereof. The compound JK12A of the present invention can be used to prepare drugs as an active ingredient for medicament or food additives. | 2015-03-05 |
| 20150065709 | Aminoquinazoline Derivative And Use Thereof In Preparing Anti-Malignant Tumor Medicament - The invention discloses a new amino-quinazoline derivative and its use in preparing drugs for preventing and/or treating malignancies. The amino-quinazoline derivative of the invention is an ideal, high effective, dual and irreversible EGFR and HER2 kinase inhibitor, and can treat or prevent various malignancy diseases, such as breast cancer, ovarian cancer, gastrointestinal cancer, oesophageal cancer, lung cancer, head and neck squamous cancer, pancreatic cancer, epidermis squamous cell cancer, prostatic cancer, neuroglioma and nasopharynx cancer. | 2015-03-05 |
| 20150065710 | EFFICIENT PROCESS FOR THE PREPARATION OF LAPATINIB AND SALTS THEREOF BY MEANS OF NEW INTERMEDIATES - The present invention refers to a new efficient process for the synthesis of the active pharmaceutical ingredient Lapatinib and salts thereof. | 2015-03-05 |
| 20150065711 | Discrete PEG Constructs - Disclosed are linear discrete PEG constructs, which can be created and produced in a precise and reproducible way. Key to being able to do these things, where x in the discrete PEG | 2015-03-05 |
| 20150065712 | METAL-MEDIATED REVERSIBLE SELF-ASSEMBLY OF CARBON NANOTUBES - There is provided a method and nanocomposite for the reversible assembly of nanotubes, such as oxidized single wall carbon nanotubes, based on metal coordination. The method produces a thermally stable, neutral nanocomposite possessing enhanced mechanical, electrical, physical and chemical properties for example. Disassembly can be provided by treatment with a competing ligand compound. | 2015-03-05 |
| 20150065713 | BORON SUBPHTHALOCYANINE COMPOUNDS AND METHOD OF MAKING - A compound comprising a boron subphthalocyanine moiety, a plurality of solubilizing substituents positioned on peripheral cyclic groups of the boron subphthalocyanine moiety and an axial substituent positioned on the boron atom. The plurality of solubilizing substituents comprise an oxygen or sulfur containing functional group and a substituted or unsubstituted, linear, branched or cyclic, aliphatic or aromatic terminal hydrocarbyl group that is 8 or more carbon atoms in length, the hydrocarbyl group optionally containing one or more heteroatoms. The axial substituent is a cyclic group selected from the group consisting of heterocyclic amine groups, diaryl ketone groups, benzotriazole groups, benzyl alcohol groups and polycyclic aromatic hydrocarbon groups, the cyclic group being bonded to the boron atom by an oxygen containing linking moiety, the cyclic group optionally being substituted with one or more additional substituents. If the axial group is a benzyl alcohol group, the alcohol substituent of the benzyl alcohol is not the oxygen containing linking moiety. | 2015-03-05 |
| 20150065714 | PRODUCTION OF ALKALOIDS BY LILIACEAE CELL CULTURE - The invention relates to the production of alkaloids from Liliaceae cell culture. | 2015-03-05 |
| 20150065715 | AMIDOPYRIDINE DERIVATIVE AND USE THEREOF - The present invention relates to novel amidopyridine derivatives. More specifically, the present invention provides a medicinal agent which is useful as a prophylactic or therapeutic agent for diseases based on the production of cytokines from T cells, comprising as the active ingredient an amidopyridine derivative or a pharmacologically acceptable salt thereof. Provided are an amidopyridine derivative of the following general formula (I): | 2015-03-05 |
| 20150065716 | COMPOUND, OPTICAL RESOLUTION METHOD, AND DERIVATIVE OF AN OPTICAL ISOMER OF AN AMINO ACID - Disclosed is a compound represented by chemical formula (1): | 2015-03-05 |
| 20150065717 | NIPECOTIC ACID DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES - A compound has an sEH-inhibiting activity and provides a pharmaceutical having a therapeutic effect and a prophylactic effect on chronic renal disease and pulmonary hypertension based on the sEH-inhibiting action. The nipecotic acid derivatives are represented by the chemical formula below and pharmaceutically acceptable salts thereof. | 2015-03-05 |
| 20150065718 | METHOD OF MAKING A TEMPLATING AGENT - A method for preparing 1-adamantyltrimethylammonium methylcarbonate or N,N-dimethyl-3,5-dimethylpiperidinium methylcarbonate is disclosed. The method comprises reacting dimethyl carbonate and 3,5-dimethylpiperidine or a 1-adamantylamine compound and in the presence of water in a sealed vessel at a temperature of from 80 to 200° C. The 1-adamantylamine compound is 1-adamantylamine, 1-adamantylmethylamine, or mixtures thereof. | 2015-03-05 |
| 20150065719 | PHARMACEUTICAL COMPOSITIONS COMPRISING N-(4-(2-AMINO-3-CHLOROPYRIDIN-4-YLOXY)-3-FLUOROPHENYL)-4-ETHOXY-1-(4-FLUO- ROPHENYL)-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE - Disclosed are salts and crystalline forms of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide and salts thereof. Also disclosed are at least one pharmaceutical composition comprising at least one crystalline form of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, at least one method of using at least one crystalline form of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide to treat cancer and/or other proliferative diseases, and processes to prepare crystalline forms of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide and salts thereof. | 2015-03-05 |
| 20150065720 | METHOD FOR SYNTHESIZING PIRFENIDONE - A process for synthesizing pirfenidone from bromobenzene having less than about 0.15% by weight dibromobenze is disclosed. Also disclosed are processes of synthesizing pirfenidone without using ethyl acetate or n-butanol, and pirfenidone having controlled levels of ethyl acetate, n-butanol, di(5-methyl-2-pyridinone)benzenes, and other impurities having specified retention times. Also disclosed are formulated dosage forms including the disclosed pirfenidone. | 2015-03-05 |
| 20150065721 | METHOD FOR PRODUCING ALKYLATED AROMATIC AMIDE DERIVATIVE - Provided is a method for producing an aromatic amide derivative represented by Formula (4), the method including a process in which an aromatic amide derivative represented by Formula (1) and a haloalkyl compound represented by Formula (3) are reacted with each other in the presence of a base and a metal or metal salt. In the formulae, each of X and Y represents a hydrogen atom, a halogen atom, or the like. A represents a hydrogen atom, an alkyl group, a group represented by Formula (2), or the like. Each of G | 2015-03-05 |
| 20150065722 | FUSED THIOPHENE DITIN MONOMERS - The disclosure relates to thiophene-based ditin compounds and methods of making and using such compounds. The disclosed compounds are novel structures having organotin groups on a conjugated aryl group spaced from and adjacent to a fused thiophene moiety. The formation of trialkyl tin groups spaced away from the fused thiophene moieties is advantageous in that it allows for novel polymerization via Stille coupling. | 2015-03-05 |
| 20150065723 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS - The present invention provides methods for the synthesis of catalysts and precursors thereof. Methods of the invention may comprise combining a catalyst precursor and at least one ligand to generate a catalytically active species, often under mild conditions and in high yields. In some cases, a wide variety of catalysts may be synthesized from a single catalyst precursor. Methods of the invention may also include the preparation of catalysts which, under reaction conditions known in the art, may have been difficult or impossible to prepare and/or isolate due to, for example, steric crowding at the metal center. The present invention also provides catalyst compositions, and precursors thereof, which may be useful in various chemical reactions including olefin metathesis. In some cases, methods of the invention may reduce the number of synthetic and purification steps required to produce catalysts and/or other reaction products, as well as reducing time, cost, and waste production. | 2015-03-05 |
| 20150065724 | DIASTEREOSELECTIVE METHODS FOR SYNTHESIZING COMPOUNDS - The present invention is directed to novel synthetic methods for preparing a compound of Structural Formula (I): | 2015-03-05 |
| 20150065725 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER - In OLEDs, improved efficiency is obtained by compounds which can form inter alia electron injection layers of the formula (I) | 2015-03-05 |
| 20150065726 | PROCESSES FOR THE PREPARATION OF ISOTHIAZOLE DERIVATIVES - Processes and intermediates for the preparation of compounds of the Formula I | 2015-03-05 |
| 20150065727 | THE NEW DERIVATIVES OF (Z)-1,2-DIPHENYLETHENE - The present invention relates to the new chemical compounds containing (Z)-1,2-diphenylethene moiety in the structures, particularly the new derivatives of cis-stilbene, the new derivatives of 4,5-diphenyl-1,3-oxazole, the new derivatives of 1-methyl-4,5-diphenyl-1H-imidazole and pharmaceutically acceptable salts thereof. The invention relates also to the application of aforementioned compounds as a microtubule-interfering agents (MIAs). The new derivatives, because of their potential antimitotic and antiangio-genic activity, can be used as ingredients in the preparations used in the treatment of cancer. | 2015-03-05 |
| 20150065728 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF - A novel compound which has excellent ultraviolet-absorbing function (especially UVA absorbing function) and excellent hydrophilicity. A benzylidene azolidine derivative represented by structural formula (I) or a salt thereof. In structural formula (I), n represents an integer of 1-5; A | 2015-03-05 |
| 20150065729 | BORON SUBPHTHALOCYANINE COMPOUNDS AND METHOD OF MAKING - A compound comprising a boron subphthalocyanine moiety, a plurality of solubilizing substituents positioned on peripheral cyclic groups of the boron subphthalocyanine moiety and an axial substituent positioned on the boron atom of the boron subphthalocyanine moiety. The plurality of solubilizing substituents comprise an oxygen or sulfur containing functional group and a substituted or unsubstituted, linear, branched or cyclic, aliphatic or aromatic terminal hydrocarbyl group that is 8 or more carbon atoms in length, the hydrocarbyl group optionally containing one or more heteroatoms. The axial substituent is selected from the group consisting of halogen, alkyloxy, haloalkyloxy, ester, carbonyl substituted alkyl, carbonyl substituted haloalkyl, alkylaryloxy, haloalkylaryloxy, alkyl sulfonyl, haloalkyl sulfonyl, alkylaryl sulfonyl and haloalkylaryl sulfonyl. The compound is not one of the following compounds: a) Phenoxytrispentadecylphenoxyboronsubphthalocyanine, b) Chlorotrispentadecylphenoxyboronsubphthalocyanine, or c) 3-Pentadecylphenoxytrispentadecylphenoxyboronsubphthalocyanine. Processes for making the compound are also taught. | 2015-03-05 |
| 20150065730 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES - The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds. | 2015-03-05 |
| 20150065731 | PROCESS FOR MICROWAVE ASSISTED SYNTHESIS OF N-METHYL PYRROLIDONE - The present invention relates to a process for microwave assisted synthesis of N-methyl pyrrolidone (NMP). Particularly the process relates to the synthesis of N-methyl succinimide or corresponding analogues by using microwave irradiation which on hydrogenation in the presence of a hydrogenating catalyst gives N-methyl pyrrolidone. Compared to the conventional heating microwave process requires less energy inputs and reduces the reaction time drastically from 5-6 h to 2-5 min. | 2015-03-05 |
| 20150065732 | METHOD FOR PREPARING REFINED LACTIDE FROM RECOVERED POLYLACTIC ACID - A method for preparing lactide from recovered polylactic acid, the method including the following steps: A. pretreating the recovered polylactic acid; B. extruding the treated polylacitc acid from a twin screw extruder to yield a polylacitc acid melt, and introducing the polylacitc acid melt to a pre-depolymerization kettle; C. carrying out a chain scission reaction to break molecular chains in the polylactic acid melt and to decrease the number-average molecular weight of the polylactic acid melt to below 5000; D. conducting depolymerization reaction to yield a crude lactide; and E. purifying the crude lactide and crystallizing the purified lactide. | 2015-03-05 |
| 20150065733 | SYNTHETIC PROCESS FOR PREPARATION OF MACROCYCLIC C1-KETO ANALOGS OF HALICHONDRIN B AND INTERMEDIATES USEFUL THEREIN - Disclosed is a compound of formula 1, or a pharmaceutically acceptable salt thereof, where R | 2015-03-05 |
| 20150065734 | PROCESS FOR PREPARING DRONEDARONE AND SALTS THEREOF - The present disclosure relates to processes for preparing dronedarone or pharmaceutically acceptable salts thereof. | 2015-03-05 |
| 20150065735 | METHOD FOR PRODUCING PURIFIED DIALKYL-FURAN-2,5-DICARBOXYLATE BY PHYSICAL SEPARATION AND SOLID LIQUID SEPARATION - A process to produce a purified dimethyl-furan-2,5-dicarboxylate (DMFD) by feeding furan dicarboxylic acid and methanol to an esterification zone to generate a crude diester composition, and purifying the crude diester composition with a physical separation process followed by crystallization, solid liquid separation, and optionally drying to produce a purified DMFD composition. A portion of the stream generated by solid liquid separation can be dissolved and subjected to crystallization and solid liquid separation repeatedly. The process is useful to produce a purified DMFD composition having a low b*, at least 98 wt. % DAFD solids, and a low concentration of 5-(methoxycarbonyl)furan-2-carboxylic acid (MCFC) and methyl 5-formylfuran-2-carboxylate (MFFC). | 2015-03-05 |
| 20150065736 | DGAT GENES FROM YARROWIA LIPOLYTICA COMBINED WITH PLASTIDIC PHOSPHOGLUCOMUTASE DOWN REGULATION FOR INCREASED SEED STORAGE LIPID PRODUCTION AND ALTERED FATTY ACID PROFILES IN OILSEED PLANTS - Transgenic soybean seed having increased total fatty acid content of at least 20% and altered fatty acid profiles when compared to the total fatty acid content of non-transgenic, null segregant soybean seed are described. DGAT genes from | 2015-03-05 |
| 20150065737 | TUNABLE RARE-EARTH FCU-METAL-ORGANIC FRAMEWORKS - Metal organic framework compostions can have a face centered cubic structure. | 2015-03-05 |
| 20150065738 | PHOSPHOROUS COMPOUND AND TRANSITION METAL COMPLEX THEREOF - The present invention provides a phosphorous compound represented by general formula (1), and transition metal complexes containing such phosphorous compounds as ligands: | 2015-03-05 |
| 20150065739 | Polylactide And Calcium Phosphate Compositions And Methods Of Making The Same - A method is provided for synthesizing polylactide/calcium phosphate composites. In one aspect, an intermediate silanized calcium phosphate material calcium-phosphate/phosphonate is developed to improve the tensile strength of the composite. | 2015-03-05 |
| 20150065740 | SLURRY PHASE DIRECT SYNTHESIS OF ORGANOHALOSILANES FROM CYCLONE FINES - The present invention is directed to a process for the synthesis of organohalosilane monomers, comprising the steps of (1) forming a slurry of cyclone fines, ultra fines and/or spent contact mass in a thermally stable solvent and reacting the agitated slurry with an organohalide of the formula R | 2015-03-05 |
| 20150065741 | I-AND II-TYPE CRYSTALS OF L-A-GLYCERYL PHOSPHORYL CHOLINE, AND METHOD FOR PREPARING SAME - The present invention relates to I- and II-type crystals of L-α-glyceryl phosphoryl choline, and to a method for preparing same. More particularly, the present invention relates to noble I- and II-type anhydride crystals of L-α-glyceryl phosphoryl choline, which have a higher purity than conventional liquid L-α-glyceryl phosphoryl choline, and one advantage of which is that formulations and dosages of pharmaceuticals are easily modified, and another advantage of which is that the hygroscopicity of the crystals are much lower than that of conventional polymorphic crystals, providing excellent stability during storage. The present invention also relates to a method for preparing the I- and II-type crystals of L-α-glyceryl phosphoryl choline. The I-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 147° C. and an absorption peak of 150° C. based on differential scanning calorimeter (DSC) analysis, and by having diffraction patterns where 28-diffraction angles are 9.8±0.2°, 12.0±0.2°, 14.3±0.2°, 15.8±0.2°, and 19.6±0.2° based on X-ray diffraction (XRD) analysis. The II-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 62° C. and an absorption peak of 66° C., and an onset temperature of 141° C. and an absorption peak of 145° C. based on DSC analysis, and having diffraction patterns where 2θ-diffraction angles are 10.3±0.2°, 12.2±0.2°, 13.4±0.2°, 14.8±0.2°, and 20.6±0.2° based on XRD analysis. | 2015-03-05 |
| 20150065742 | METHOD FOR PRODUCING NITROUS ACID ESTER, AND METHOD FOR PRODUCING DIALKYL OXALATE AND DIALKYL CARBONATE - A method for producing nitrous acid ester in which nitric oxide, oxygen, and an alcohol are reacted, thereby generating nitrous acid ester includes a step of generating nitrous acid ester by supplying a bottom liquid from a bottom part of the reaction column, and nitric oxide and/or carbon monoxide, a step of supplying nitrous acid ester to the reaction column; a step of supplying a reaction liquid containing water, nitric acid, and the alcohol to a nitric acid condensing column from the reactor; and a step of separating a low-boiling point component by distillation from the reaction liquid under control of a concentration of the alcohol in a condensed liquid being generated at a bottom part of the nitric acid condensing column to be less than 4.0% by weight so as to introduce the condensed liquid into the reactor from the nitric acid condensing column. | 2015-03-05 |
| 20150065743 | METHODS FOR PRODUCING BORYLATED ARENES - Methods for the selective borylation of arenes, including arenes substituted with an electron-withdrawing group (e.g., 1-chloro-3-fluoro-2-substituted benzenes) are provided. The methods can be used, in some embodiments, to efficiently and regioselectively prepare borylated arenes without the need for expensive cryogenic reaction conditions. | 2015-03-05 |
| 20150065744 | METHOD FOR PRODUCING ACRYLONITRILE - The invention relates to a method for producing acrylonitrile which includes a vapor phase catalytic ammoxidation process of performing vapor phase catalytic ammoxidation by bringing a source gas containing propylene, molecular oxygen, and ammonia into contact with a fluidized bed catalyst to obtain acrylonitrile. The method is characterized in that the fluidized bed catalyst is a catalyst containing molybdenum and bismuth and the vapor phase catalytic ammoxidation process is performed while maintaining an adsorbed amount of ammonia per specific surface area (m | 2015-03-05 |
| 20150065745 | Method of Manufacturing Bio-Diesel and Reactor - A reactor and process for the production of bio-diesel. The reactor includes one or more coiled reaction lines. The lines are positioned within a tank containing a heat transfer media such as molten salt, maintained at about 750° F. A pump circulates the media within the tank. An emulsion of alcohol; refined feed stock, including glycerides and/or fatty acids; and preferably water is pumped through the reaction lines at temperatures and pressures sufficient to maintain the alcohol in a super-critical state. The curvature of the coils, pump pulsing, and the flow rate of the emulsion keep the emulsion in a turbulent state while in the reactor, ensuring thorough mixing of the alcohol and feed stock. The alcohol reacts with the glycerides and fatty acids to form bio-diesel. The reaction is fast, efficient with regard to energy input and waste generation, and requires minimal alcohol. | 2015-03-05 |
| 20150065746 | FLUOROSURFACTANTS HAVING IMPROVED BIODEGRADABILITY - To address the problem of insufficient biodegradability of perfluorinated surfactants, the present invention provides biodegradable fluorosurfactants derived from olefins having —CHR, —CHRf, —CHF, and/or —CH | 2015-03-05 |
| 20150065747 | Process for ProducingTerephthalic Acid - A solid terephthalic acid composition and a process for producing terephthalic acid from para-xylene. The process comprises forming a mixture comprising the para-xylene, a solvent, a bromine source, and a catalyst; and oxidizing the para-xylene by contacting the mixture with an oxidizing agent at oxidizing conditions to produce a solid oxidation product comprising terephthalic acid, para-toluic acid, 4-carboxybenzaldehyde. The solvent comprises a carboxylic acid having from 1 to 7 carbon atoms and an dialkyl imidazolium ionic liquid; and the catalyst comprises at least one of cobalt, titanium, manganese, chromium, copper, nickel, vanadium, iron, molybdenum, tin, cerium, and zirconium. The solid terephthalic acid composition comprises, less than about 4,000 ppm-wt 4-carboxybenzaldehyde content, and more than about 2,000 ppm-wt a para-toluic acid. | 2015-03-05 |
| 20150065748 | PROCESS FOR SEPARATING ARYL CARBOXYLIC ACIDS - In the present disclosure, a process for separating aryl carboxylic acids from a mixture comprising a plurality of aryl carboxylic acids is provided, wherein the process comprising the steps of heating a first mixture that comprises at least two aryl carboxylic acids wherein each of said aryl carboxylic acids having a pre-determined liquefaction temperature and a pre-determined precipitation temperature, with at least one ionic compound, at a pre-determined temperature to obtain a liquefied composition; and cooling the liquefied composition under controlled temperature conditions to fractionally crystallize and precipitate an aryl carboxylic acid. The precipitated aryl carboxylic acid is isolated and the obtained mother liquor is subjected to iterated cooling steps until each of the remaining aryl carboxylic acids precipitates one by one. The mother liquor remains in liquefied form. | 2015-03-05 |
| 20150065749 | CATALYTIC OXIDATION OF URONIC ACIDS TO ALDARIC ACIDS - Disclosed is the oxidation of uronic acids, such as galacturonic acid, to the corresponding aldaric acids (characterized by the formula HOOC—(CHOH)n-COOH, with n being an integer of from 1 to 5) such as galactaric acids. The starting material comprising the uronic acid is subjected to oxygen under the influence of a supported gold catalyst and in the presence of a base. The oxidation occurs in good selectivity and yield, under unexpectedly mild conditions. A source of galacturonic acids is pectin, such as that derived from sugar beet pulp. | 2015-03-05 |
| 20150065750 | Preparation of 4-Amino-2,4-Dioxobutanoic Acid - A process for synthesizing 4-amino-2,4-dioxobutanoic acid involves reacting diethyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding ethyl cyanoacetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl 2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl 2-cyano-3-hydroxy-butenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoic acid. | 2015-03-05 |
| 20150065751 | Preparation of 4-Amino-2,4-Dioxobutanoic Acid - A first process for synthesizing 4-amino-2,4-dioxobutanoate involves reacting a dialkyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding an alkyl cyanoacetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl 2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl 2-cyano-3-hydroxy-butenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoate. A second process for synthesizing 4-amino-2,4-dioxobutanoate involves reacting a dialkyl oxalate with an alkoxide in ethanol to form a reaction mixture, and afterward adding acetonitrile to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product in the form of an alkali salt of the formula ethyl 3-cyano-2-oxopropenolate, and then isolating the ethyl 3-cyano-2-oxopropenolate , and afterward either (a) reacting the ethyl 3-cyano-2-oxopropenolate with an aqueous hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoate; or (b) reacting the ethyl 3-cyano-2-oxopropenolate with hydrogen peroxide and ion exchange resin under conditions suitable to form 4-amino-2,4-dioxobutanoate. In these processes, the 4-amino-2,4-dioxobutanoate may be acidified into 4-amino-2,4-dioxobutanoic acid. | 2015-03-05 |
| 20150065752 | PROCESS FOR ISOLATING KUKOAMINE - The present invention provides a process for isolating kukoamine by solid phase extraction using a polyamide or a derivative thereof as an adsorbent. Said process is convenient, economical and environmental-friendly, and obtains highly purified kukoamines with a high yield. | 2015-03-05 |
