| 10th week of 2015 patent applcation highlights part 58 |
| Patent application number | Title | Published |
|---|
| 20150064749 | METHODS FOR PRODUCING POLYUNSATURATED FATTY ACID AND LIPID CONTAINING POLYUNSATURATED FATTY ACID - A method for producing a polyunsaturated fatty acid (PUFA) or a lipid containing a PUFA, a microbial cell containing a PUFA, and use of the microbial cell are provided. A method for producing a polyunsaturated fatty acid (PUFA) or a lipid containing a PUFA including culture of a microorganism capable of producing arachidonic acid (ARA) and/or dihomo-gamma-linolenic acid (DGLA) is provided, the method including at least one of the following steps: (a) adding an organic acid in an amount of 0.01 to 5 w/v % to a culture medium after the beginning of main culture; (b) increasing the pH of the culture medium to a range effective for culture after the beginning of the main culture; and (c) adding a metal sulfate in an amount of 0.01 to 0.5 w/w % to the main culture medium. | 2015-03-05 |
| 20150064750 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE - The invention provides non-naturally occurring microbial organisms having a toluene, benzene, p-toluate, terephthalate, (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate, (2-hydroxy-4-oxobutoxy)phosphonate, benzoate, styrene, 2,4-pentadienoate, 3-butene-1ol or 1,3-butadiene pathway. The invention additionally provides methods of using such organisms to produce toluene, benzene, p-toluate, terephthalate, (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate, (2-hydroxy-4-oxobutoxy)phosphonate, benzoate, styrene, 2,4-pentadienoate, 3-butene-1ol or 1,3-butadiene. | 2015-03-05 |
| 20150064751 | METHODS FOR CONTROL OF FLUX IN METABOLIC PATHWAYS THROUGH PROTEASE MANIPULATION - The embodiments described herein pertain to cells, and methods for preparing cells, that can be used as biocatalysts by altering enzymes that compete for a substrate or product of a pathway of interest such that the targeted enzyme is sensitive to a site-specific protease, which protease is expressed but relocated in the cell to a site where it is not in contact with the targeted enzyme in the intact cell. Upon cell lysis, the protease contacts the target enzyme, which is then inactivated by protease cleavage. | 2015-03-05 |
| 20150064752 | POLYPEPTIDE CONFERRING ACID TOLERANT PROPERTY TO YEAST CELL, POLYNUCLEOTIDE ENCODING THE SAME, YEAST CELL HAVING INCREASED AMOUNT OF THE POLYPEPTIDE, METHOD OF PRODUCING A PRODUCT BY USING THE YEAST CELL, AND METHOD OF PRODUCING ACID-TOLERANT YEAST CELL - A polypeptide conferring an acid-tolerant property on a yeast cell, a polynucleotide encoding the polypeptide, a yeast cell including an increased amount of the polypeptide, a method of producing a product by using the yeast cell, and a method of producing an acid-tolerant yeast cell are provided. | 2015-03-05 |
| 20150064753 | CORYNEBACTERIUM COMPRISING NAD+ DEPENDENT FORMATE DEHYDROGENASE GENE AND METHOD FOR PRODUCING C4 DICARBOXYLIC ACID USING THE SAME | 2015-03-05 |
| 20150064754 | BIOPRODUCTION OF CHEMICALS - The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products. | 2015-03-05 |
| 20150064755 | RECOMBINANT BACTERIA COMPRISING NOVEL SUCROSE TRANSPORTERS - Recombinant bacteria capable of metabolizing sucrose are described. The recombinant bacteria comprise in their genome or on at least one recombinant construct, a novel nucleotide sequence encoding a polypeptide having sucrose transporter activity and a nucleotide sequence encoding a polypeptide having sucrose hydrolase activity. These nucleotide sequences are each operably linked to the same or a different promoter. Recombinant bacteria capable of metabolizing sucrose to produce glycerol and/or glycerol-derived products such as 1,3-propanediol and 3-hydroxypropionic acid are also described. | 2015-03-05 |
| 20150064756 | ENZYMATIC ALKENE CLEAVAGE - The invention relates to an enzyme that comprises or includes a sequence according to SEQ. ID No. 1 or SEQ. ID No. 2, to a method for the production thereof, and to the use thereof as a catalyst in the oxidative cleavage of vinyl aromatics. | 2015-03-05 |
| 20150064757 | NOVEL CAR ENZYMES AND IMPROVED PRODUCTION OF FATTY ALCOHOLS - The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells. | 2015-03-05 |
| 20150064758 | MICROORGANISM COMPRISING PYRUVATE DEHYDROGENASE VARIANT AND METHOD OF PRODUCING C4-CHEMICALS USING THE SAME - A recombinant microorganism including pyruvate dehydrogenase having increased activity may increase 1,4-BDO production under anaerobic conditions, as well as a method for preparing same, and method of using same to produce a C4 chemical. | 2015-03-05 |
| 20150064759 | MODIFIED MICROORGANISM AND METHODS OF USING SAME FOR PRODUCING 2-PROPANOL AND1-PROPANOL AND/OR 1,2-PROPANEDIOL - The present disclosure provides a non-naturally occurring microorganism comprising: one or more polynucleotides encoding one or more enzymes in a pathway that produces acetyl-CoA; one or more polynucleotides encoding one or more enzymes in a pathway that catalyze a conversion of cytosolic acetyl-CoA to 2-propanol; one or more polynucleotides encoding one or more enzymes in a pathway that catalyze a conversion of dihydroxyacetone-phosphate to 1-propanol and/or 1,2-propanediol, wherein the microorganism has reduced levels of pyruvate decarboxylase enzymatic activity (e.g., the microorganism comprises a disruption of one or more enzymes that decarboxylate pyruvate and/or a disruption of one or more transcription factors of one or more enzymes that decarboxylate pyruvate), and wherein the microorganism is capable of growing on a C6 sugar as a sole carbon source under anaerobic conditions. Also provided are methods of using the disclosed non-naturally occurring microorganisms in methods for the coproduction of 2-propanol and 1-propanol and/or 1,2-propanediol. | 2015-03-05 |
| 20150064760 | MODIFIED MICROORGANISM AND METHODS OF USING SAME FOR PRODUCING BUTADIENE AND 1-PROPANOL AND/OR 1,2-PROPANEDIOL - The present disclosure provides a non-naturally occurring microorganism comprising: one or more polynucleotides encoding one or more enzymes in a pathway that produces acetyl-CoA; one or more polynucleotides encoding one or more enzymes in a pathway that catalyze a conversion of crotonyl alcohol, 5-hydroxy-3-ketovaleryl-CoA, 3-ketopent-4-enoyl-CoA, or 3,5-ketovaleryl-CoA to butadiene; one or more polynucleotides encoding one or more enzymes in a pathway that catalyze a conversion of dihydroxyacetone-phosphate to 1-propanol and/or 1,2-propanediol, wherein the microorganism has reduced levels of pyruvate decarboxylase enzymatic activity (e.g., the microorganism comprises a disruption of one or more enzymes that decarboxylate pyruvate and/or a disruption of one or more transcription factors of one or more enzymes that decarboxylate pyruvate), and wherein the microorganism is capable of growing on a C6 sugar as a sole carbon source under anaerobic conditions. Also provided are methods of using the disclosed non-naturally occurring microorganisms in methods for the coproduction of butadiene and 1-propanol and/or 1,2-propanediol. | 2015-03-05 |
| 20150064761 | PROCESS OF PRODUCING BIOENERGY WITH LOW CARBON DIOXIDE EMISSIONS AND ZERO-WASTE OF BIOMASS - Disclosed herein is a bioenergy production system with reduced carbon dioxide emissions and process wastes; including a process for producing a bioalcohol and a biogas by subjecting a biomass, such as: herbaceous and woody plants, fruit pulp, freshwater and sea algae, grains, aerobic and anaerobic sludge, saccharides, polyols and carbohydrates, to a combined process of a biosaccharification/alcohol fermentation, including a biomass pretreatment process; and a process for producing a methane biogas with a reduced level of carbon dioxide and hydrogen sulfide, via an algae cultivation process with a view to purifying the carbon dioxide and hydrogen sulfide contained in the biogas; wherein, when the algae to be cultivated is microalgae, biodiesel is produced by subjecting the harvested microalgae to a biodiesel manufacturing process while recycling the glycerol and the saccharide-containing waste produced as byproducts to the biosaccharification/alcohol fermentation process, and when the algae to be cultivated is macroalgae the harvested macroalgae is recycled to the biosaccharification/alcohol fermentation process. The method of the present invention is effective in reducing carbon dioxide emissions, a representative green house gas contributing to the global warming, and also in optimizing a zero-waste bioenergy production system. | 2015-03-05 |
| 20150064762 | SYSTEM AND METHOD FOR THE INTEGRATED PRODUCTION OF FIRST AND SECOND GENERATION ETHANOL AND THE USE OF INTEGRATION POINTS FOR SUCH PRODUCTION - The present invention refers to a system and a process for the production of ethanol and related products from lignocellulosic biomasses (second generation—2G—ethanol), particularly from sugarcane bagasse and straw, however not limited thereto, integrated with conventional processes for the production of ethanol (first generation—1G—ethanol) such as, for example, from sugarcane juice and/or molasses (a process that is typically Brazilian, either in sugar and ethanol plants or in autonomous distilleries), corn, grain, wheat, sugary sorghum, white beetroot, among others, comprising the recovery/reuse of streams and effluents. More specifically, the present invention refers to an integrated process for the production of ethanol and related products where the said process warrants increased efficiency particularly in the use of the raw material, steam, electric power and treated water. | 2015-03-05 |
| 20150064763 | Method for Producing Hydrocarbons and Oxygen-containing Compounds from Biomass - The present invention generally relates to biochemical and chemical industry, and more particularly to a method which can be used in fermenting carbohydrate substrates of plant origin for producing C | 2015-03-05 |
| 20150064764 | TRANSPORTING, TRAPPING AND ESCAPPING MANIPULATION DEVICE FOR MAGNETIC BEAD BIOMATERIAL COMPRISING MICRO-MAGNETOPHORETIC CIRCUIT - A device for transporting, trapping and escaping a single biomaterial using a magnetic structure, and a method of transporting, trapping and escaping of the single biomaterial using the same are provided, and a method is provided for controlling movement and direction of the single biomaterial including soft magnetic micro structure and magnetic structure in a linear, square storage, apartment type, radial soft magnetic micro structure. Accordingly, the device for transporting, trapping and escaping a single biomaterial and the method for transporting, trapping and escaping single biomaterial using the same can control movement on the lap-on-a-chip with increased precision and ease, by using magnetic force, and thus can be advantageously used in the field of magneto-resistive sensor, or categorization of single cells or biomolecules. | 2015-03-05 |
| 20150064765 | POLYPEPTIDE EXPRESSION METHOD - A method for the production of a polypeptide of interest in a host cell, which method comprises: a. providing a host cell which harbours a nucleic acid encoding a polypeptide of interest, wherein the polypeptide of interest is modified so that it comprises fewer methionine and/or lysine residues than a reference polypeptide, excluding any initial methionine amino acid located at the N-terminal end of the polypeptide sequence; b. cultivating the host cell under conditions suitable for production of the polypeptide; and, optionally, c. recovering the compound of interest. The invention also relates to a modified polypeptide which comprises fewer methionine and/or lysine residues than a reference polypeptide, excluding any initial methionine amino acid located at the N-terminal end of the polypeptide sequence. | 2015-03-05 |
| 20150064766 | BETA-GLUCOSIDASE VARIANTS - The invention relates to recombinantly produced β-glucosidase variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant β-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target β-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue. | 2015-03-05 |
| 20150064767 | COMPOSITIONS AND METHODS COMPRISING VARIANT MICROBIAL PROTEASES - The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications. | 2015-03-05 |
| 20150064768 | Systems and Methods for Virus Propagation in Cell Cultures for Vaccine Manufacture - The present invention provides a closed system to propagate virus-infected cells without the effect of shear force, while providing quicker access to nutrients than is available conventionally. This system design allows for a high density of infected cell growth to increase the virus yields and to maintain homogeneity of the contents of the main container. The system further provides a nuclease to degrade the cellular DNA prior for purification of the virus or viral components. As the system is designed for maximum containment at low risk, the live virus can be a hazardous virus such as a Bio-safety Level 3 (BSL 3), BSL 4 or BSL5 virus. | 2015-03-05 |
| 20150064769 | Methods for Inactivating Viruses During a Protein Purification Process - The present application relates to novel and improved methods of achieving virus inactivation during a protein purification process. | 2015-03-05 |
| 20150064770 | TUNING BACTERIOPHAGE HOST RANGE - Various aspects and embodiments of the invention are directed to high-throughput phage-engineering methods and recombinant bacteriophages with tunable host ranges for controlling phage specificity. | 2015-03-05 |
| 20150064771 | INDUCIBLE GENE EXPRESSION COMPOSITION FOR USING EUKARYOTIC POL-2 PROMOTER-DRIVEN TRANSCRIPTION IN PROKARYOTES AND THE APPLICATIONS THEREOF - Eukaryotic protein-coding messenger RNAs and non-coding microRNAs are naturally transcribed by type II RNA polymerases (pol-2) but not prokaryotic RNA polymerases. As a result, current eukaryotic RNA and protein production is performed either using eukaryotic pol-2 promoters in hybridomas or mammalian cells or using prokaryotic promoters in bacterial cells. However, because prokaryotic RNA transcription tends to be error-prone, frequent mutation is a big problem. Also, growing hybridomas or mammalian cells is relatively laborious and costly. To overcome these problems, the present invention provides a novel inducible composition and method for producing eukaryotic RNAs and/or their related peptides/proteins directly using eukaryotic pol-2 promoter-driven gene expression in fast growing bacteria, without the need of changing to prokaryotic promoters or growing hybridomas/mammalian cells. The RNAs and peptides/proteins so obtained can be used to develop drugs, cure diseases, treat tumors/cancers, produce pluripotent stem (iPS) cells, enhance wound healing, and make foods. | 2015-03-05 |
| 20150064772 | NON-RECOMBINANT SACCHAROMYCES STRAINS THAT GROW ON XYLOSE - The present invention relates to methods for producing | 2015-03-05 |
| 20150064773 | Detergent Composition and Substitution of Optical Brighteners in Detergent Composition - The present invention relates to a method for reformulating a detergent composition wherein a first detergent formulation comprising an optical brightener is reformulated by reducing the amount of optical brightener by at least 20% and including a cellulase. The invention further relates to detergent compositions comprising an optical brightener and a cellulase wherein the optical brightener is comprised at a level of at most 0.75% by weight of the composition and the cellulase is present in an amount of atleast 0.5 ECU/g of the composition. | 2015-03-05 |
| 20150064774 | MICROFLUIDIC APPARATUS - A microfluidic apparatus mounted on a rotation driving unit for inducing a fluid to flow due to a centrifugal force includes: a target chamber that houses a first fluid; a first chamber that houses a second fluid and is disposed closer to a rotation center of the microfluidic apparatus in a radius direction than the target chamber, the first chamber being connected to the target chamber by a first channel; a first valve that prevents a flow of the second fluid through the first channel; and a second chamber disposed closer to the rotation center in the radius direction than the target chamber and connected to the target chamber by a second channel, wherein the first fluid is transported to the second chamber by supplying the second fluid to the target chamber by the centrifugal force. | 2015-03-05 |
| 20150064775 | RANDOM ACCESS SYSTEM AND METHOD FOR POLYMERASE CHAIN REACTION TESTING - A random access, high-throughput system and method for preparing a biological sample for polymerase chain reaction (PCR) testing are disclosed. The system includes a nucleic acid isolation/purification apparatus and a PCR apparatus. The nucleic acid isolation/purification apparatus magnetically captures nucleic acid (NA) solids from the biological sample and then suspends the NA in elution buffer solution. The PCR testing apparatus provides multiple cycles of the denaturing, annealing, and elongating thermal cycles. More particularly, the PCR testing apparatus includes a multi-vessel thermal cycler array that has a plurality of single-vessel thermal cyclers that is each individually-thermally-controllable so that adjacent single-vessel thermal cyclers can be heated or cooled to different temperatures corresponding to the different thermal cycles of the respective PCR testing process. | 2015-03-05 |
| 20150064776 | SAMPLE DISH AND COMPRESSED GAS MICROBIAL TEST UNIT - Provided is a sample dish for detecting microbes. The sample dish includes a base having an opening extending therethrough, an outer side wall at the outer periphery of the base, and an inner side wall at the inner periphery of the base defined by the opening. The sample dish may be used in conjunction with a microbial test unit including a housing defining an internal cavity configured to contain a sample dish, the unit including a cuff extending from an outlet of the housing into the internal cavity. The cuff may be an open-ended member configured to extend through an opening of the sample dish and provide fluid communication between the internal cavity and the outlet. The microbial test unit provides the ability to test compressed gas directly input to the unit. | 2015-03-05 |
| 20150064777 | APPARATUS FOR DETECTING MICROORGANISMS - Provided is an apparatus for detecting microorganisms, including: a sample accommodation container having an accommodation space in which a measurement sample in which a number of living microorganisms is to be counted is accommodated; an electrode portion installed at the sample accommodation container so as to apply electrical stimulation to the microorganisms of the sample accommodated in the accommodation space; a current applying control portion that is capable of controlling a current applied by the electrode portion; and an image processor that captures an image of the sample accommodated in the sample accommodation container and counts the number of living microorganisms. Accordingly, the number of living microorganisms can be easily identified by electrically stimulating the living microorganisms, and by comparing an image of the living microorganisms generated before electrical stimulation is applied to the living microorganisms with an image of the living microorganisms generated after electrical stimulation is applied to the living microorganisms, the number of living microorganisms can be easily measured. | 2015-03-05 |
| 20150064778 | RAMAN SPECTROSCOPIC APPARATUS, RAMAN SPECTROSCOPIC METHOD, AND ELECTRONIC APPARATUS - A Raman spectroscopic apparatus analyzes a substance under analysis and includes a light source that emits light of a first wavelength, an optical device that adsorbs the substance under analysis and is irradiated with the light of the first wavelength, and an optical detector that receives light radiated from the optical device. The optical device includes a first structural member that generates charge transfer resonance in response to the light of the first wavelength and a second structural member that is less than or equal to 5 nm from the first structural member and generates surface plasmon resonance in response to the light of the first wavelength. The first structural member is made of a metal or a semiconductor, and the second structural member is made of a metal different from the material of the first structural member. | 2015-03-05 |
| 20150064779 | METHOD AND APPARATUS FOR PRODUCING A TUBE PARTIALLY HAVING A NON-CIRCULAR CROSS SECTION AND HAVING CIRCULAR END PORTIONS AND USE THEREOF - Disclosed is a method for the production of a tube having, in sections, a non-circular profile by deforming, comprising:
| 2015-03-05 |
| 20150064780 | DISPOSABLE SINGLE USE SELF-CONTAINED CYCLIC PRESSURE AND FLOW BIOREACTOR SYSTEM - The present invention provides for a bioreactor system ( | 2015-03-05 |
| 20150064781 | REPAIR AND REGENERATION OF OCULAR TISSUE USING POSTPARTUM-DERIVED CELLS - Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed. | 2015-03-05 |
| 20150064782 | PRODUCTION OF FATTY ACID DERIVATIVES - The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell cultures engineered to produce fatty acid derivative compositions comprising fatty acids, fatty alcohols, fatty aldehydes, fatty esters, alkanes, terminal olefins, internal olefins or ketones. The fatty acid derivative composition is produced extracellularly with a higher titer, yield or productivity than the corresponding wild type or non-engineered host cell. | 2015-03-05 |
| 20150064783 | CELL PERMEABLE FUSION PROTEIN FOR FACILITATING REPROGRAMMING INDUCTION AND USE THEREOF - A method of preparing a reprogramming induced pluripotent stem cell from a human-derived somatic cell using a fusion protein in which a reprogramming inducing factor and cell permeable peptide (CPP) are fused, and a fusion protein in which a reprogramming inducing factor and a cell permeable peptide are fused are disclosed. | 2015-03-05 |
| 20150064784 | Methods For Culturing Undifferentiated Cells Using Sustained Release Compositions - Methods for culturing undifferentiated mammalian cells, such as stem and progenitor cells, are provided. The methods involve incubating the cell in the presence of a sustained release composition containing at least one growth factor, wherein the sustained release composition continuously releases the growth factor(s), and wherein the presence of the sustained level of growth factor maintains the cell in an undifferentiated state. | 2015-03-05 |
| 20150064785 | CELL CULTURE MEDIA AND METHODS - Compositions and methods are described for preparing media, feeds, and supplements. Such methods and medias may display increased stability of labile components and may use, for example, microsuspension and/or encapsulation technologies, chelation, and optionally, coating and/or mixing the labile compounds with anti-oxidants. The compositions may withstand thermal and/or irradiation treatment and have reduced virus number. These techniques may result in product with extended shelf-life, extended release of their internal components into culture, or in product that can be added aseptically into a bioreactor using minimal volumes. The compositions and methods may optimize the bioproduction workflow and increase efficiency. | 2015-03-05 |
| 20150064786 | IN VITRO MODEL FOR NEURONAL DEATH - This invention demonstrates the formation of a novel polarized membrane lipid raft signaling module in neurons, in response to several diverse neurotoxic stimuli. This polarization occurs well before neurons commit to die, and is an early mechanism in death signaling. The formation of this signaling module is dependent on cholesterol for its formation and provides a mechanistic explanation for the protective effects of cholesterol depleting drugs in several non-neural models of cell death. As such, the formation of the signaling module lends itself as a novel screen for the identification of new drugs and therapeutics which would retard its formation and protect against neuronal injury and death. | 2015-03-05 |
| 20150064787 | Host Cell Modification with Artificial Endosymbionts - The present invention is directed generally to host cells with artificial endosymbionts, wherein the artificial endosymbiont and the host cell communicate with each other to alter a phenotype of the host cell. In some embodiments, the communication comprises the secretion of a polypeptide from the artificial endosymbiont into the host cell. The secreted polypeptide can be a selectable marker, a reporter protein, a transcription factor, a signal pathway protein, a receptor, a growth factor, a cytokine, an effector molecule or other factors that can produce a phenotype in the host cell. | 2015-03-05 |
| 20150064788 | RETROVIRAL TRANSDUCTION USING POLOXAMERS - The present invention relates to a method for transducing a target cell, the method comprising the step of contacting a target cell with a retroviral vector and a poloxamer having a molecular weight of 12.8 kDa to about 15 kDa. Further, the invention relates to the use of a poloxamer as defined herein, optionally in combination with a polycationic substance as defined herein, for transducing a target cell with a retroviral vector and a kit comprising a retroviral vector, a poloxamer as defined herein and, optionally, instructions for use. | 2015-03-05 |
| 20150064789 | COMPOSITIONS FOR LINKING DNA-BINDING DOMAINS AND CLEAVAGE DOMAINS - Disclosed herein are compositions for linking DNA binding domains and cleavage domains (or cleavage half-domains) to form non-naturally occurring nucleases. Also described are methods of making and using compositions comprising these linkers. | 2015-03-05 |
| 20150064790 | ENGINEERED ZINC FINGER PROTEINS TARGETING 5-ENOLPYRUVYL SHIKIMATE-3-PHOSPHATE SYNTHASE GENES - The present disclosure relates to engineered zinc finger proteins that target 5-enolpyruvyl shikimate-3-phosphate synthase (EPSPS) genes in plants and methods of using such zinc finger proteins in modulating gene expression, gene inactivation, and targeted gene modification. In particular, the disclosure pertains to zinc finger nucleases for targeted cleavage and alteration of EPSPS genes. | 2015-03-05 |
| 20150064791 | Microfluidic-based Gene Synthesis - A method for synthesizing long DNA constructs from oligonucleotide precursors directly within a microfluidic device uses several oligonucleotides at once. A precursor mix containing at least two oligonucleotide precursors with at least partial base complementarity is introduced into an input of a microfluidic chip and at least one cycle of at least one gene synthesis protocol is applied to fabricate a DNA construct containing the sequence of at least two oligonucleotide precursors. A method for the synthesis of a modified DNA construct includes electroporating at least one oligonucleotide encoding for at least one point mutation and having homology with at least one DNA region of a target cell into the target cell and incorporating the oligonucleotide into the target cell DNA through the action of recombination protein beta or a recombination protein beta functional homolog. | 2015-03-05 |
| 20150064792 | STANDARD SOLUTION FOR USE IN ANALYSIS OF AMINO ACID IN PLASMA - An external standard solution for use in the analysis of amino acid in plasma, containing,
| 2015-03-05 |
| 20150064793 | METHOD OF DISCERNING SUBSTITUTION OF CARBOHYDRATE ESTERS - A method of testing for discerning substitution of carbohydrate ester includes the step of providing a predetermined amount of a solution. Further, the method also includes adding ammonium hydroxide and sodium borohydride to the solution. The method also includes the step of transferring the solution to an ammonium ion exchange cartridge and collecting the eluate from the cartridge. Also included in the method is the step of analyzing the sample in a mass spectrometer to produce a mass spectrum. Further, the method includes calculating the amu of phosphate and sulfate substitution of the ion and comparing it to the actual amu of the found ion. | 2015-03-05 |
| 20150064794 | BIORELEVANT COMPOSITIONS - This application relates to a homogeneous biorelevant composition for preparing fasted state biorelevant media having a surface tension between 25 mN/m and 50 mN/m for simulating fasted state gastric and fasted state upper small intestinal fluids of mammalian species, especially humans, dogs, etc. comprising at least one bile salt, eg. sodium taurocholate or sodium taurodeoxycholate; at least one phospholipid, especially 60-99 wt % phosphatidylcholine (PC), enzyme digested diacylphospholipids containing 50-90 wt % of monoacyl-PC; or mixtures thereof; and at least one fatty acid or monovalent salt of the fatty acid, such as sodium oleate. The application also relates to an aqueous biorelevant media composed of surfactants occurring in the gastrointestinal tract of mammals, in particular when prepared from above homogeneous biorelevant composition. | 2015-03-05 |
| 20150064795 | SAMPLE ANALYZER AND SAMPLE ANALYZING METHOD - Disclosed is a sample analyzer comprising: a measurement unit including a reagent storage capable of holding a plurality of kinds of reagents, the measurement unit configured to measure a sample by use of a plurality of kinds of reagents held in the reagent storage in combination; a memory in which a calibration curve is stored in association with a reagent set used in creation of the calibration curve; and a controller programmed to perform operations, comprising: in a case where no calibration curve corresponding to a reagent set used in measurement of the sample has been stored, storing, in the memory, information indicating that the reagent set used in the measurement of the sample has been used in measurement, and when creating a calibration curve, automatically extracting the reagent set for which no calibration curve has been stored and for which the information has been stored. | 2015-03-05 |
| 20150064796 | NONINVASIVE DETECTION OF LUNG CANCER USING EXHALED BREATH - A non-invasive method of detecting or screening for lung cancer in a subject specimen is provided. The method includes detecting elevated levels of one or more carbonyl-containing volatile organic compounds (VOCs) that are biomarkers for lung cancer in exhaled breath from the subject specimen. The method may further include obtaining exhaled breath from the subject specimen; forming adducts of the carbonyl-containing VOCs with a reactive chemical compound; quantifying the adducts of the carbonyl-containing VOCs to establish a subject value for each of the adducts; and comparing each subject value to a threshold healthy specimen value for each of the adducts of the carbonyl-containing VOCs. One or more subject values at quantities greater than threshold healthy specimen values are also useful for screening for lung cancer in the subject specimen. | 2015-03-05 |
| 20150064797 | METHOD FOR QUANTITATIVELY ANALYZING CYSTEINE AND CYSTINE AND REAGENT KIT FOR QUANTITATIVELY ANALYZING CYSTEINE AND CYSTINE - A method for quantitatively analyzing cysteine and cysteine includes a first step of adding a methyl-sulfurating agent to a sample that includes cysteine and cystine to obtain a methyl-sulfurated cysteine, a second step of adding a derivatizing agent to the methyl-sulfurated cysteine and the cystine to obtain a cysteine derivative and a cystine derivative, respectively, and a third step of quantifying the cysteine derivative and the cystine derivative. | 2015-03-05 |
| 20150064798 | ORGANIC THIN-FILM TRANSISTOR SENSOR ARRANGEMENTS - A sensor includes an organic thin-film transistor (OTFT) that operates under low voltage conditions in an aqueous environment. According to an example embodiment, an OTFT includes an organic channel that electrically connects source and drain electrodes, with a gate electrode separated from the channel by a dielectric layer. The channel, gate and dielectric layer are arranged to facilitate switching of the channel region to pass current between the source and drain electrodes, in response to a low voltage applied to the gate electrode, when the channel is exposed to an aqueous solution. The current that is passed is indicative of characteristics of the aqueous solution, and is used to characterize the same. For various implementations, the low voltage operation of the sensor facilitates such characterization with substantially no ionic conduction through an analyte in the aqueous solution. | 2015-03-05 |
| 20150064799 | EXCITATION-DEPENDENT FLUORESCENT ORGANIC NANOPARTICLES - A series of self-assembled monoacylglycerol clusters with excitation-dependent visible fluorescence have been developed. | 2015-03-05 |
| 20150064800 | DIAGNOSTIC DEVICES, METHODS AND SYSTEMS FOR DETECTING PLATELET FACTOR 4 (PF4)/HEPARIN ANTIBODIES - The present invention provides a novel assay for detecting human antibodies specific for a platelet factor 4 (PF4)/heparin complex in a fluid sample. The assay utilizes an immobilized PF4/polyanion complex and an anti-human antibody conjugated to a non-particulate fluorescent dye to capture and detect human PF4/heparin antibodies. Various devices, methods and systems based on the disclosed PF4/heparin assay are also provided. | 2015-03-05 |
| 20150064801 | METHOD FOR PRODUCING REAGENT FOR ANTIBODY DETECTION AND USE THEREOF - The present invention provides the following: a method for efficiently producing a reagent for detecting an antibody that specifically binds with an insoluble antigen protein present in a liquid sample; a reagent for antibody detection produced by the production method; and a use of the antibody. In a step for solubilizing an antigen protein, it is possible to efficiently solubilize and recover the antigen protein by using a cationizing agent; therefore, when compared to conventional methods, it is possible to efficiently produce a reagent for detecting an antibody that has bound to multiple antigen protein molecules in a carrier. | 2015-03-05 |
| 20150064802 | MODULE TRANSPORT SYSTEM THAT CAN BE COMBINED INTO AN AUTOMATION SYSTEM - An integrated automation system for use in transporting samples between modules, the system can include a plurality of modules configured to be connected to one another for processing samples, each of the plurality of modules having an internal transport system. Each internal transport system includes one or more periphery track portions integrated within a respective module, each of the periphery track portions having two ends and one or more transverse track portions integrated within the respective module, the one or more transverse track portions intersecting at least one of the one or more periphery track portions. The internal transport systems can be configured to connect to one another via one end of the two ends connecting to one end of the two ends of adjacent periphery track portions, thereby forming a continuous periphery track running through and connecting the plurality of modules. Samples are transported along the continuous periphery track and the one or more transverse track portions. The continuous periphery track and the one or more transverse track portions form a plurality of paths along which the samples are transported. | 2015-03-05 |
| 20150064803 | TEST MASS COMPENSATION OF MASS MEASUREMENT DRIFT IN A MICROCANTILEVER RESONATOR - The present disclosure provides methods and mechanisms for measuring small masses attached to a substrate within a microcantilever. Specifically, the disclosure describes the measurement of small particles accumulated at a substrate that cannot be flowed through a microchannel within a microcantilever. A resonance measurement is acquired at a first time. A pair resonance measurements is then acquired at a second point in time one with the test mass at a first position off or along the microcantilever, the second with the test mass at a second position along the microcantilever. Comparing the resonance frequencies determined for the two test mass positions allows for disambiguation of changes in the mass of the particles from changes in the resonant behavior of the microcantilever itself. | 2015-03-05 |
| 20150064804 | METHOD FOR MANUFACTURING NIOBATE-SYSTEM FERROELECTRIC THIN FILM DEVICE - There is provided a method for manufacturing a niobate-system ferroelectric thin film device, including: a lower electrode film formation step of forming a lower electrode film on a substrate; a niobate-system ferroelectric thin film formation step of forming a niobate-system ferroelectric thin film on the lower electrode film; an etch mask formation step of forming a desired etch mask pattern on the niobate-system ferroelectric thin film; and a ferroelectric thin film etching step of forming a desired fine pattern of the niobate-system ferroelectric thin film by wet etching using an etchant including an aqueous alkaline solution of a chelating agent. | 2015-03-05 |
| 20150064805 | METHOD FOR FABRICATING MAGNETORESISTIVE RANDOM ACCESS MEMORY ELEMENT - A magnetoresistive random access memory (MRAM) element includes a bottom electrode embedded in a first insulating layer; an annular reference layer in a first via hole of a second insulating layer on the first insulating layer, the annular reference layer being situated above the bottom electrode; a first gap fill material layer filling the first via hole; a barrier layer covering the annular reference layer, the second insulating layer and the first gap fill material layer; an annular free layer in a second via hole of a third insulating layer on the second insulating layer, the annular free layer being situated above the annular reference layer; and a top electrode stacked on the annular free layer. | 2015-03-05 |
| 20150064806 | MAGNETIC TRAP FOR CYLINDRICAL DIAMAGNETIC MATERIALS - A system for self-aligning diamagnetic materials includes first and second magnets contacting each other along a contact line and having a diametric magnetization perpendicular to the contact line and a diamagnetic rod positioned to levitate above the contact line of the first and second magnets. | 2015-03-05 |
| 20150064807 | METHOD OF REPAIRING ORGANIC LIGHT-EMITTING DISPLAY APPARATUS - A method of repairing an organic light-emitting display apparatus, the organic light-emitting display apparatus including a substrate, an organic light-emitting device formed on the substrate, a thin film transistor (TFT) formed on the substrate, an organic insulating layer formed on the TFT, and a conductive pattern formed on the organic insulating layer, the conductive pattern including a shorted part between two conductive elements in the conductive pattern, the method including: removing the short by using a focused ion beam (FIB). | 2015-03-05 |
| 20150064808 | LED THIN-FILM DEVICE PARTIAL SINGULATION PRIOR TO SUBSTRATE THINNING OR REMOVAL - LED dies are partially singulated while on an unthinned depth growth substrate. Slots are made through the streets separating the LED dies, but not through the growth substrate, leaving the now separated LED dies on the growth substrate. A secondary support is attached to the LED dies on the opposite surface from the growth substrate, and the growth substrate is thinned or removed, leaving the LED dies on the secondary support. Because the LED dies are separated while on the unthinned growth substrate, the likelihood of distortion before slicing is virtually eliminated, and the width of the streets between the LED dies may be correspondingly reduced. | 2015-03-05 |
| 20150064809 | SUBSTRATE SUPPORT SYSTEM - A method and apparatus for a substrate support system for a substrate process chamber, the chamber comprising a chamber body enclosing a processing region, a primary substrate support and a secondary substrate support at least partially disposed in the processing region, the secondary substrate support circumscribing the primary substrate support, wherein one or both of the primary substrate support and the secondary substrate support are movable relative to each other, and the primary substrate support is rotatable relative to the secondary substrate support. | 2015-03-05 |
| 20150064810 | Low Contamination Chamber for Surface Activation - An embodiment low contamination chamber includes a gas inlet, an adjustable top electrode, an adjustable bottom electrode, and an outlet. The chamber is configured to adjust a distance between the adjustable top and bottom electrodes in accordance with a desired density of plasma disposed between the top electrode and the bottom electrode. | 2015-03-05 |
| 20150064811 | METHOD OF MANUFACTURING NITRIDE SEMICONDUCTOR DEVICE, AND BURN-IN APPARATUS - A method of manufacturing a nitride semiconductor device, the nitride semiconductor device having an input terminal, a drain terminal, a gate terminal, and an output terminal, includes a burn-in step in which the nitride semiconductor device is heated while inputting an RF signal to the input terminal, applying a drain voltage to the drain terminal, and applying a gate voltage to the gate terminal. The burn-in step is continued until the nitride semiconductor device exhibits a decrease in gate current. | 2015-03-05 |
| 20150064812 | METHOD OF FORMING A SEMICONDUCTOR DEVICE EMPLOYING AN OPTICAL PLANARIZATION LAYER - A method for the manufacture of a semiconductor device is provided, including the steps of providing a semiconductor substrate including a first area separated from a second area by a first isolation region, wherein the second area includes an intermediate transistor comprising a gate electrode, forming an oxide layer over the first and second areas, forming an organic planarization layer (OPL) over the oxide layer, forming a mask layer over the OPL in the first area without covering the OPL in the second area, and etching the OPL with the mask layer being present to expose the oxide layer over the gate electrode of the transistor. | 2015-03-05 |
| 20150064813 | MICROPROCESSOR IMAGE CORRECTION AND METHOD FOR THE DETECTION OF POTENTIAL DEFECTS - Systems and methods are provided for developing usable chip images in order to detect and screen defects or anomalies in a manufacturing environment. More specifically, a method is provided for manufacturing at least one wafer or chip. The method includes obtaining image data of the at least one wafer or chip. The method further includes correcting the image data to remove normal variation within the image data. The method further includes comparing the corrected image data to image data for at least one other wafer or chip to determine whether the corrected image data for the at least one wafer or chip shows a defect or anomaly beyond that of the normal variation. The method further includes placing the at least one wafer or chip into a category of fabrication based on the comparison. | 2015-03-05 |
| 20150064814 | MECHANISMS FOR MONITORING ION BEAM IN ION IMPLANTER SYSTEM - In accordance with some embodiments, an assembly of an ion implanter system is provided. The assembly includes a control unit, a wafer holder and a detecting device. The wafer holder and the detecting device are respectively positioned at two sides of the control unit. The control unit is configured to drive the wafer holder and the detecting device to rotate about at least one rotation axis. | 2015-03-05 |
| 20150064815 | Method of Making Molded LED Package - Methods of packaging a light emitting diode (LED) include providing a first lead having a first recess in a bottom surface and a second lead having a second recess in a bottom surface, placing a LED die over a top surface of at least one of the first and the second leads, electrically connecting the LED die to the first lead and to the second lead, forming a package around the LED die that includes an opening in its upper surface exposing at least the LED die, and separating the package containing the LED die, the first lead and the second lead from a lead frame such that the package contains a first castellation and a second castellation in a side surface of the package, such that the castellations expose the leads and/or a first platable metal which is electrically connected to the leads. | 2015-03-05 |
| 20150064816 | METHOD FOR MAKING LIGHT EMITTING DIODE - A method for making light emitting diode, the method includes the following steps. A substrate having an epitaxial growth surface is provided. A carbon nanotube layer is suspended above the epitaxial growth surface. A first semiconductor layer, an active layer and a second semiconductor layer are grown on the epitaxial growth surface in that order. A third semiconductor layer is formed on a surface of the second semiconductor layer, wherein the third semiconductor layer includes a plurality of spaced protrusions. A portion of the first semiconductor layer is exposed by etching a portion of the third semiconductor layer, the second semiconductor layer, and the active layer. A first electrode is formed to electrically connected to the first semiconductor layer and a second electrode is formed to electrically connected to the second semiconductor layer. | 2015-03-05 |
| 20150064817 | ELECTRICALLY CONTROLLED OPTICAL FUSE AND METHOD OF FABRICATION - Embodiments of the present invention provide an electrically controlled optical fuse. The optical fuse is activated electronically instead of by the light source itself. An applied voltage causes the fuse temperature to rise, which induces a transformation of a phase changing material from transparent to opaque. A gettering layer absorbs excess atoms released during the transformation. | 2015-03-05 |
| 20150064818 | METHODS OF MANUFACTURING OLED PIXEL AND DISPLAY DEVICE - A method of manufacturing an Organic Light Emitting Diode (OLED) pixel is disclosed. The method includes forming an anode and forming a pixel definition layer. The pixel definition layer includes a first sub-pixel area, a second sub-pixel area, a third sub-pixel area corresponding to the third sub-pixel, and a pixel spacing area. The first sub-pixel, the second sub-pixel and the third sub-pixel are separated from each other by the pixel spacing area. The method also includes coating a long-chain fatty acid ester layers on the pixel spacing area, the second sub-pixel area, and the third sub-pixel area, coating light emitting layers on the sub-pixel areas and on the long-chain fatty acid ester layers, and ashing the substrate and removing the long-chain fatty acid ester layers to form light emitting patterns. The method also includes forming a cathode. | 2015-03-05 |
| 20150064819 | METHOD FOR MANUFACTURING ORGANIC LIGHT EMITTING DIODE DISPLAY - A manufacturing method of an organic light emitting device may include the following. A panel displaying an image is formed. A buffering member including a dummy buffering member is adhered to the panel. A film is adhered to an upper surface of the buffering member. The film and the dummy buffering member are removed. | 2015-03-05 |
| 20150064820 | ORGANIC LIGHT EMITTING DIODE DISPLAY, MANUFACTURING METHOD AND MANUFACTURING EQUIPMENT THEREOF - A method for manufacturing an OLED display according to an exemplary embodiment comprises: forming a thermosetting adhesive layer having a getter receiving portion on a metal sheet; forming a display unit including a plurality of pixels on a substrate; forming a getter layer at an external side of the display unit on the substrate; adhering the thermosetting adhesive layer and the metal sheet to the substrate so as to locate the getter layer in the getter receiving unit; and hardening the thermosetting adhesive layer. The forming of the thermosetting adhesive layer includes layering a solid thermosetting adhesive sheet which has been patterned so as to have the getter receiving portion on the metal sheet. | 2015-03-05 |
| 20150064821 | METHOD FOR FABRICATING NANO-PATTERNED SUBSTRATE FOR HIGH-EFFICIENCY NITRIDE-BASED LIGHT-EMITTING DIODE - Provided is a method of manufacturing a nitride-based light emitting diode. According to the method, a substrate having a nano to micron sized pattern including a bottom section and a convex section, wherein a lower end diameter of the convex section is 0.1 to 3 times a light emitting wavelength of the light emitting diode, and a buffer layer formed on the substrate and formed as a GaN layer are manufactured. According to the method of manufacturing the nitride-based light emitting diode, light extraction is significantly improved, and the nano to micron sized pattern, economically formed. | 2015-03-05 |
| 20150064822 | Deep Ultraviolet Light Emitting Diode - A method of fabricating a light emitting diode, which includes an n-type contact layer and a light generating structure adjacent to the n-type contact layer, is provided. The light generating structure includes a set of quantum wells. The contact layer and light generating structure can be configured so that a difference between an energy of the n-type contact layer and an electron ground state energy of a quantum well is greater than an energy of a polar optical phonon in a material of the light generating structure. Additionally, the light generating structure can be configured so that its width is comparable to a mean free path for emission of a polar optical phonon by an electron injected into the light generating structure. | 2015-03-05 |
| 20150064823 | METHOD FOR MANUFACTURING LIGHT EMITTING ELEMENT - A method for manufacturing a light emitting element that includes preparing a wafer having a substrate and a semiconductor structure, the substrate including a plurality of protrusions at positions corresponding to lattice points on a triangular lattice. The method includes forming a plurality of first modified parts in the substrate by irradiating the substrate with a laser beam along first dividing lines, forming a plurality of second modified parts in the substrate by irradiating the substrate with a laser beam along second dividing lines, and dividing the wafer along the first modified parts and the second modified parts to obtain a plurality of light emitting elements. | 2015-03-05 |
| 20150064824 | OPTICAL DEVICE AND MANUFACTURING METHOD THEREFOR - An optical device including a substrate formed of a light transmitting material and a light emitting layer formed on the front surface of the substrate. Both the front surface and the back surface of the substrate are parallel to each other and have substantially the same rectangular shape. The substrate has four side surfaces connecting the front surface and the back surface of the substrate. Each side surface of the substrate has a corrugated sectional shape such that a plurality of concave portions and convex portions are alternately formed. | 2015-03-05 |
| 20150064825 | DISPLAY APPARATUS MANUFACTURING METHOD - A thin film encapsulation manufacturing apparatus includes a first cluster configured to form a first inorganic layer on a first substrate, on which an emission unit is formed, by a sputtering process; a second cluster configured to form a first organic layer on the first inorganic layer on the first substrate conveyed from the first cluster by an organic deposition process; a first connection module configured to connect the first cluster and the second cluster, configured to convey the first substrate on which the first inorganic layer is formed from the first cluster to the second cluster, and configured to cool the first substrate in a non-contact manner; and a third cluster configured to form a second inorganic layer on the first organic layer on the first substrate conveyed from the second cluster by a chemical vapor deposition (CVD) process or a plasma enhanced chemical vapor deposition (PECVD) process. | 2015-03-05 |
| 20150064826 | LIGHT-SCATTERING SUBSTRATE, METHOD OF MANUFACTURING THE SAME, ORGANIC LIGHT-EMITTING DISPLAY DEVICE INCLUDING THE SAME, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DISPLAY DEVICE - A light-scattering substrate which can be thinned and has improved thermal resistance, a method of manufacturing the same, an organic light-emitting display device including the same, and a method of manufacturing the organic light-emitting display device are disclosed. The light-scattering substrate includes a light-scattering layer composed of a plurality of metal nanoparticles which are attached to at least a surface of a substrate. The metal nanoparticles are formed by agglomeration of a metal on the substrate, and show a surface plasmon phenomenon. | 2015-03-05 |
| 20150064827 | METHOD FOR MANUFACTURING SOLID-STATE IMAGE SENSOR - A first pixel includes a first charge accumulation portion of a first conductivity type in a first region. A second pixel includes a second charge accumulation portion of the first conductivity type in a second region and a semiconductor region of a second conductivity type in a third region. Impurities of the second conductivity type are doped in the third region and the impurities of the second conductivity type are doped in at least the second region to generate a first difference between quantities of doping the impurities of the second conductivity type in the first and second regions. Impurities are doped in the first and second regions to reduce a second difference, caused by the first difference, between net quantities of doping impurities of the first conductivity type in the first and second regions. | 2015-03-05 |
| 20150064828 | METHOD OF MANUFACTURING INK FOR FORMING FUNCTIONAL LAYER AND METHOD OF MANUFACTURING ORGANIC EL ELEMENT - A method of manufacturing an ink for forming a functional layer includes: dispersing a mixture in which a low molecular material and a high molecular material are mixed in a poor solvent; and dissolving the mixture by adding a good solvent to the poor solvent in which the mixture is dispersed, in which a volume ratio of the poor solvent is from 10% to 70% with respect to the total volume in which the good solvent is added to the poor solvent and the poor solvent and the good solvent can be mixed. | 2015-03-05 |
| 20150064829 | CHEMICAL SENSOR WITH SIDEWALL SPACER SENSOR SURFACE - In one implementation, a chemical sensor is described. The chemical sensor includes chemically-sensitive field effect transistor including a floating gate conductor having an upper surface. A dielectric material defines an opening extending to the upper surface of the floating gate conductor. A conductive sidewall spacer is on a sidewall of the opening and contacts the upper surface of the floating gate conductor. | 2015-03-05 |
| 20150064830 | THERMOELECTRIC DEVICES HAVING REDUCED THERMAL STRESS AND CONTACT RESISTANCE, AND METHODS OF FORMING AND USING THE SAME - A method includes preparing a thermoelectric material including p-type or n-type material and first and second caps including transition metal(s). A powder precursor of the first cap can be loaded into a sintering die, punches assembled thereto, and a pre-load applied to form a first pre-pressed structure including a first flat surface. A punch can be removed, a powder precursor of the p-type or n-type material loaded onto that surface, the punch assembled to the die, and a second pre-load applied to form a second pre-pressed structure including a second substantially flat surface. The punch can be removed, a powder precursor of the second cap loaded onto that surface, the first punch assembled to the die, and a third pre-load applied to form a third pre-pressed structure. The third pre-pressed structure can be sintered to form the thermoelectric material; the first or second cap can be coupled to an electrical connector. | 2015-03-05 |
| 20150064831 | MANUFACTURE OF SOLAR CELL MODULE - A solar cell module is manufactured by encapsulating a solar cell matrix comprising a plurality of electrically connected solar cell components between a transparent panel and a backsheet with a resin. The method involves (i) embossing opposite surfaces of a green silicone rubber sheet, (ii) arranging a transparent panel ( | 2015-03-05 |
| 20150064832 | Elevated Photodiode with a Stacked Scheme - A device includes an image sensor chip having formed therein an elevated photodiode, and a device chip underlying and bonded to the image sensor chip. The device chip has a read out circuit electrically connected to the elevated photodiode. | 2015-03-05 |
| 20150064833 | Connector of connecting light sensor and substrate and method of fabricating light sensor - A connector of connecting a light sensor and a substrate is utilized for rotating the light sensor so that the light-receiving direction of the light sensor is parallel with the substrate. When the connector is utilized in an optical touch system, the light sensor can be disposed on the substrate of the optical touch system by means of general manufacturing facilities of flat display panels. Meanwhile, the light-receiving direction of the light sensor is parallel with the substrate of the optical touch system. | 2015-03-05 |
| 20150064834 | IMAGE SENSOR INTEGRATED CIRCUIT PACKAGE WITH REDUCED THICKNESS - An image sensor die may include a pixel array formed in an image sensor substrate. The image sensor die may be mounted to a thin metal interconnect layer that has been deposited on a sacrificial carrier substrate. The thin metal interconnect layer may include one or more metal layers that are patterned to form metal traces that serve as contact pads, signal lines, and other interconnects in the interconnect layer. The image sensor die may be wire bonded, flip-chip mounted, or otherwise mechanically and electrically coupled to the metal interconnect layer. The sacrificial carrier substrate may be etched or otherwise removed to expose the metal interconnects on the metal interconnect layer. An array of solder balls may be formed on the exposed metal interconnects to form a ball grid array package, or the exposed contact pads may be plated to form a leadless chip carrier package. | 2015-03-05 |
| 20150064835 | METHOD FOR PRODUCING A SOLAR CELL - The invention relates to a method for producing a solar cell having a substrate made of silicon, which substrate has a silicon oxide layer present on the surface of the substrate and an antireflection layer applied to the silicon oxide layer, which antireflection layer is deposited onto the dielectric passivation layer in a process chamber. According to the invention, in order to achieve a stability of corresponding solar cells or solar cell modules produced therefrom against a potential induced degradation (PID), the dielectric passivation layer is formed from the surface of the substrate in the process chamber by means of a plasma containing an oxidizing gas. | 2015-03-05 |
| 20150064836 | RANGE MODULATED IMPLANTS FOR IMAGE SENSORS - Image sensors may include a plurality of photodiodes. The photodiodes may be isolated from each other using isolations regions formed from p-well or n-well implants. Deep and narrow isolation regions may be formed using a multi-step process that selectively places implants at desired depths in a substrate. If desired, the multi-step process may include only one photolithographic patterning step, which in turn can help reduce costs, fabrication time, and alignment errors. The process may include passing ions through a stack of alternating layers of material such as alternating layers of oxide and nitride. After each implant, a layer in the stack may be removed and ions may be passed through the layers remaining in the stack to form an implant at a different depth in the substrate. | 2015-03-05 |
| 20150064837 | ORGANIC ELECTRONIC DEVICES WITH MULTIPLE SOLUTION-PROCESSED LAYERS - A method of fabricating a tandem organic photosensitive device involves depositing a first layer of an organic electron donor type material film by solution-processing of the organic electron donor type material dissolved in a first solvent; depositing a first layer of an organic electron acceptor type material over the first layer of the organic electron donor type material film by a dry deposition process; depositing a conductive layer over the interim stack by a dry deposition process; depositing a second layer of the organic electron donor type material over the conductive layer by solution-processing of the organic electron donor type material dissolved in a second solvent, wherein the organic electron acceptor type material and the conductive layer are insoluble in the second solvent; depositing a second layer of an organic electron acceptor type material over the second layer of the organic electron donor type material film by a dry deposition process, resulting in a stack. | 2015-03-05 |
| 20150064838 | SELF-ASSEMBLED ORGANIC MONOLAYER HYBRID MATERIALS AND METHODS THEREOF - Self-assembled monolayer hybrid materials having a modified carboxylic acid deposited from the gas-phase onto a metal oxide substrate, methods of using targeted α-carbon modified carboxylic acids to rapidly deposit activated organic molecules into a self-assembled monolayer on metal oxide substrates, and the self-assembled monolayer hybrid materials capable of being used in various industries, such as optoelectronics and separation science. | 2015-03-05 |
| 20150064839 | METHOD OF FORMING TIN OXIDE SEMICONDUCTOR THIN FILM - A method of forming a tin oxide semiconductor thin film includes preparing a precursor solution including a tin oxide semiconductor, coating the precursor solution on a substrate; and performing a heat treatment on the substrate coated with the precursor solution. A tin compound having a different tin valence according to a semiconductor type of the tin oxide semiconductor may be used in the precursor solution. | 2015-03-05 |
| 20150064840 | METHOD FOR FORMING OXIDE FILM, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE - A method for forming a single crystal oxide film with high productivity is provided. Further, a method for forming a single crystal oxide film at a lower temperature is provided. In addition, a method for forming a single crystal oxide film by a simpler method is provided. An oxide film having crystal parts is formed over a formation surface, and the oxide film is single crystallized by performing heat treatment. Further, an oxide film having crystal parts in which the c-axis are aligned in a direction parallel to a normal direction of the formation surface or a normal direction of a surface of the oxide film and having no crystal grain boundary between the crystal parts is used as the oxide film formed over the formation surface. | 2015-03-05 |
| 20150064841 | SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF - The number of manufacturing steps is reduced to provide a semiconductor device with high productivity and low cost. A semiconductor device with low power consumption and high reliability is provided. A photolithography process for forming an island-shaped semiconductor layer is omitted, and a semiconductor device is manufactured through at least four photolithography processes: a step for forming a gate electrode (including a wiring or the like formed from the same layer), a step for forming a source electrode and a drain electrode (including a wiring or the like formed from the same layer), a step for forming a contact hole, and a step for forming a pixel electrode. In the step for forming the contact hole, a groove portion is formed, whereby formation of a parasitic transistor is prevented. The groove portion overlaps with the wiring with an insulating layer provided therebetween. | 2015-03-05 |
| 20150064842 | ARRAY SUBSTRATE AND METHOD OF FABRICATING THE SAME - An array substrate includes an oxide semiconductor layer; an etch stopper including a first contact hole exposing each of both sides of the oxide semiconductor layer; source and drain electrodes spaced apart from each other with the oxide semiconductor layer therebetween; a first passivation layer including a contact hole exposing each of both ends of the oxide semiconductor layer and each of ends of the source and drain electrode that oppose the both ends of the oxide semiconductor layer, respectively; and a connection pattern at the second contact hole contacting both the oxide semiconductor layer and each of the source and drain electrodes. | 2015-03-05 |
| 20150064843 | STACKED SEMICONDUCTOR PACKAGE AND METHOD FOR MANUFACTURING THE SAME - A stacked semiconductor package includes a first semiconductor chip having a first surface and a second surface which faces away from the first surface and including first bonding pads which are formed on the first surface and first through electrodes which pass through the first surface and the second surface; a second semiconductor chip stacked over the second surface of the first semiconductor chip, and including second bonding pads which are formed on a third surface facing the first semiconductor chip and second through electrodes which pass through the third surface and a fourth surface facing away from the third surface and are electrically connected with the first through electrodes; and a molding part formed to substantially cover the stacked first and second semiconductor chips and having openings which expose one end of the first through electrodes disposed on the first surface of the first semiconductor chip. | 2015-03-05 |
| 20150064844 | Multichip Power Semiconductor Device - An electronic device includes a first chip carrier and a second chip carrier isolated from the first chip carrier. A first power semiconductor chip is mounted on and electrically connected to the first chip carrier. A second power semiconductor chip is mounted on and electrically connected to the second chip carrier. An electrically insulating material is configured to at least partially surround the first power semiconductor chip and the second power semiconductor chip. An electrical interconnect is configured to electrically connect the first power semiconductor chip to the second power semiconductor chip, wherein the electrical interconnect has at least one of a contact clip and a galvanically deposited conductor. | 2015-03-05 |
| 20150064845 | METHOD OF FORMING AN INTEGRATED CIRCUIT PACKAGE - A method of fabricating an integrated circuit package assembly comprises forming solder bumps over a first surface of a first integrated circuit package. The method also comprises forming at least one first support structure over the first surface of the first integrated circuit package or over a second surface of a second integrated circuit package. The method further comprises mounting the first integrated circuit package over a second integrated circuit package. The first integrated circuit package is mounted over the second integrated circuit package with the first surface facing the second surface, and the at least one first support structure is electrically isolated. | 2015-03-05 |
| 20150064846 | Semiconductor Device - A number of semiconductor chips each include a first main face and a second main face opposite to the first main face. A first encapsulation layer is applied over the second main faces of the semiconductor chips. An electrical wiring layer is applied over the first main faces of the first semiconductor chips. A second encapsulation layer is applied over the electrical wiring layer. The thickness of the first encapsulation layer and the thicknesses of the first semiconductor chips is reduced. The structure can be singulated to obtain a plurality of semiconductor devices. | 2015-03-05 |
| 20150064847 | METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE AND ADHESIVE FOR MOUNTING FLIP CHIP - The present invention aims to provide a method for producing a semiconductor device, the method being capable of achieving high reliability by suppressing voids. The present invention also aims to provide a flip-chip mounting adhesive for use in the method for producing a semiconductor device. The present invention relates to a method for producing a semiconductor device, including: step 1 of positioning a semiconductor chip on a substrate via an adhesive, the semiconductor chip including bump electrodes each having an end made of solder; step 2 of heating the semiconductor chip at a temperature of the melting point of the solder or higher to solder and bond the bump electrodes of the semiconductor chip to an electrode portion of the substrate, and concurrently to temporarily attach the adhesive; and step 3 of removing voids by heating the adhesive under a pressurized atmosphere, wherein the adhesive has an activation energy ΔE of 100 kJ/mol or less, a reaction rate of 20% or less at 2 seconds at 260° C., and a reaction rate of 40% or less at 4 seconds at 260° C., as determined by differential scanning calorimetry and Ozawa method. | 2015-03-05 |
| 20150064848 | SEMICONDUCTOR DEVICE HAVING A DIAMOND SUBSTRATE HEAT SPREADER - In accordance with one or more embodiments, a semiconductor device comprises a semiconductor die having a heat region disposed on at least one portion of the semiconductor die, and a diamond substrate disposed proximate to the semiconductor die, wherein the diamond substrate is capable of dissipating heat from the diamond substrate via at least one or more bumps coupling the diamond substrate to the heat region of the semiconductor die. | 2015-03-05 |
