| 10th week of 2015 patent applcation highlights part 57 |
| Patent application number | Title | Published |
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| 20150064647 | ULTRASONIC RING TIP TO ACTIVATE ENDODONTIC INSTRUMENTS - A new ultrasonic tip is used to activate endodontic files and includes a tubular body; a ring disposed at one end of the tubular body, the ring having an external diameter and an internal diameter; and the ring having a cut to permit easy insertion of the endodontic file; and a threaded hole at the other end of the tubular body, the threaded hole being capable of screwing onto an ultrasonic hand piece. | 2015-03-05 |
| 20150064648 | DENTAL HANDPIECE HAVING A ROLLING BEARING - A dental handpiece ( | 2015-03-05 |
| 20150064649 | TURBINE DENTAL DRILL MECHANISM AND TURBINE HEAD WITH SAME MOUNTED THEREIN - A turbine dental drill mechanism, which includes a turbine and a turbine shaft. A balancing chamber is provided on the mechanism and includes an automatic balancing component provided therein. The automatic balancing component is a metal ball, sand grains or a flexible body. The metal ball in the balancing chamber can enhance the balance. The sand grains in the balancing chamber can reduce noise while also enhancing balance. The flexible body in the balancing chamber can eliminate noise and provide weight adjustment, thereby achieving automatic balancing. | 2015-03-05 |
| 20150064650 | ADJUSTABLE DENTAL SPACER - A dental spacer that is adjustable and attaches to a tooth. The dental spacer may include a ring with an inner surface and an outer surface. A screw may be secured to the ring to compress and expand the ring size. A spacer may be attached to the outer surface of the ring and may abut against an adjacent tooth. Therefore, the space between two teeth adjacent to a removed tooth may be preserved. | 2015-03-05 |
| 20150064651 | ELASTIC TONGUE-DORSUM RETRACTION DEVICE, CLAMPING PLIERS, INSTALLATION PLIERS, LINE GUIDE AND IMPLANTATION METHOD - The present invention relates to an elastic tongue-dorsum refraction device for treating obstructive sleep apnea/hypopnea syndrome (OSAHS), clamping pliers, installation pliers, a line guide, and an implantation method. The elastic tongue-dorsum refraction device of the present invention includes a tongue dorsum connection mechanism, an elastic retractor and a tooth-side fastener. The tongue dorsum connection mechanism is disposed at the tongue dorsum portion, the tooth-side fastener is fixed to teeth or the alveolar bone or outside the maxilla and mandible lips, one end of the elastic retractor is connected to the tooth-side fastener, and the other end of the elastic retractor is connected to the tongue dorsum connection mechanism. In this way, an elastic retraction device using the tooth-side fastener as a fulcrum is formed. By pulling up the sagging tongue root forward, stenosis and obstruction of the airway at the glossopharyngeal portion are prevented, thereby providing a function of treating snoring and OSAHS. Since the elastic refractor exerts an elastic retraction force on the tongue dorsum portion, the movement of the tongue tip is not affected when the tongue root is properly pulled up, so that a clear language function and an adequate swallowing function can be maintained, and not only the airway at the glossopharyngeal portion is enlarged, but also good comfort is provided. In addition, the present invention further discloses clamping pliers, installation pliers and a line guide for use together with the elastic tongue-dorsum retraction device, and an implantation method of the elastic tongue-dorsum retraction device. | 2015-03-05 |
| 20150064652 | IMPLANT AND DENTAL PROSTHESES SYSTEM - An implant for anchoring a tooth replacement includes an endosseous part comprising a ceramic sleeve at a first end of the endosseous part. The endosseous part is configured to be embedded to a full height of the endosseous part in a bone. | 2015-03-05 |
| 20150064653 | Denture Reference and Registration System - An improved denture system is disclosed. An improved denture system has a support bar and an artificial denture base. The denture base has an oversize cutout and a corresponding cavity and the support bar has a plurality of reference posts which mechanically interface with the corresponding cavity so that the support bar is connected to the artificial denture base and provides reinforcement and stability to the denture system. The shape and position of the reference posts fully constrains the support bar in a fixed position with reference to the denture base. In one embodiment, the denture base snap-fits onto the support bar. | 2015-03-05 |
| 20150064654 | MODIFICATION OF CERAMIC SURFACES - A fluoride treated ceramic material is provided, the ceramic material comprising fluorinated metal oxide on its surface. A method for the preparation of such treated ceramics is also provided, the method involving exposure of the ceramic to a fluorine-containing reagent. The ceramic materials can be further functionalized so as to bond to functional ligands and/or resins. The ceramic materials can be, for example, ceramic medical implants or particulate ceramic, which can be incorporated within dental and/or orthopedic composites. | 2015-03-05 |
| 20150064655 | Personal Casualty Simulator - A system and method uses three-dimensional, visual feedback for simulated weapons fire during training of a soldier in a combat exercise. In the system, the soldier is provided with a weapon equipped with a laser transmitter that simulates the firing of actual rounds. Further, sensors are positioned on a human target. Also, discharge members are located on the human target. When a signal is received by a sensor, selected discharge members are activated to immediately expel a plume of dust. As a result, the plume of expelled dust provides three-dimensional, visual feedback to the soldier in real-time. | 2015-03-05 |
| 20150064656 | SHARING FLIGHT RESOURCES - Systems and methods are described for sharing flight resources between a plurality of flight entities. A method may include identifying a flight resource that is to be shared between flight entities where the flight resource has a profile having a definition of the flight resource and attributes that identifies the flight resource. A shared schedule that is associated with the flight resource can be generated and the shared schedule can be provided to the flight entities that have been identified as being authorized to schedule and use the flight resource. An authorized flight entity can schedule the flight resource by providing a request to schedule the flight resource during a block of time. | 2015-03-05 |
| 20150064657 | UNMANNED VEHICLE SIMULATION - A method of simulating a launch of an unmanned air vehicle may include providing an interface for a user selectable launch option for a plurality of simulation modes, and responsive to a user input at the interface, simulating a launch of an unmanned air vehicle into an orbit using a predefined launch model and orbit parameters. | 2015-03-05 |
| 20150064658 | UNMANNED VEHICLE SIMULATION - A system for simulating a vehicle may include a designing tool for configured for a vehicle simulation and a simulation tool for controlling simulation characteristics of the vehicle. A method for simulating an object may include displaying a map of a region, displaying a plurality of actions operative on a simulated object, and performing a selected action. | 2015-03-05 |
| 20150064659 | METHODS FOR MOTOR VEHICLE DRIVER RISK REDUCTION AND DEVICES THEREOF - A method, non-transitory computer readable medium, and a driver intervention device that obtains an indication of a risk event associated with a motor vehicle driver. At least one human factor of the motor vehicle driver that contributed to the risk event is retrieved based on a correlation with the indicated risk event. At least one recommended intervention is determined for the motor vehicle driver based on a match of the at least one human factor of the motor vehicle driver. The determined at least one recommended intervention is output to a computing device associated with the motor vehicle driver. | 2015-03-05 |
| 20150064660 | Kit Of Pre-Construction Samples For Replicating Construction Products - The present invention is a pre-construction sample that is made of a flexible material and has a product image corresponding to an actual construction product. The pre-construction sample is preferably at least 18 inches in one dimension. The pre-construction sample is preferably produced by a printing process having at least 200 dpi, and more preferably 300 dpi. Kits of pre-construction samples are provided to assist the consumer choosing from among various construction products, such as flooring, decking, countertops, cabinets, windows, shingles, among others. | 2015-03-05 |
| 20150064661 | ELECTRONIC DEVICE AND METHOD FOR MANAGING SOFTWARE TOOLS - Method of managing software tools using an electronic device includes initializing a three dimensional (3D) cube on a user interface of a software. The 3D cube includes cube surfaces. Each of the cube surfaces has been divided into blocks. A tool of the software is loaded on each of the blocks of each of the cube surfaces. In response to detecting a rotation signal on the 3D cube, a selected cube surface is determined. In response to detecting a touch signal on the selected cube surface, selected blocks on a same layer on the selected cube surface are determined, and a rotation direction of the layer is determined based on the touch signal. Current blocks are determined on the selected cube surface by rotating the layer according to the rotation direction. Icons of tools corresponding to the current blocks are displayed on the selected cube surface. | 2015-03-05 |
| 20150064662 | DEVICE AND METHOD FOR TREATING ABNORMAL MUSCLE FUNCTION - A myoelectric computer interface device is disclosed that includes a myoelectric controller, a computer interface and a monitor. The computer interface includes at least one computer-implementable software program that comprises executable code, wherein the executable code comprises at least one member selected from the group consisting of: instructions for mapping at least one muscle activity to cursor icon movement and instructions for orthogonal or other mapping of co-activated muscles. | 2015-03-05 |
| 20150064663 | LANGUAGE LEARNING PROGRAM AND COMPUTER READABLE RECORDING MEDIUM HAVING THE SAME - There are disclosed a computer readable recording media recording a language learning program to execute a method including a first step of receiving input of a first video file selected by a user in a computer, a second step of receiving input of a first text associated with the first video file, and a step of generating an execution file configured to execute the first video file and to stand by in a first state where a voice can be input after executing the first video file. | 2015-03-05 |
| 20150064664 | Method And Apparatus For Teaching The Pronunciation of Alphabet Characters Of An Unfamiliar Language - Method and apparatus for teaching a student the pronunciation of alphabet characters of an unfamiliar language include providing a group of distinct sequential narrative media segments, each narrative media segment including a partial transliterated narrative text comprising words of a base language known to the student formed by base characters of a base alphabet, and wherein a number of target characters comprising a subset of the target alphabet are substituted in the text for corresponding base characters of the base alphabet, the sequential media segments containing successively increasing numbers of target characters of the target alphabet substituted for corresponding base characters of the base alphabet; and displaying each narrative media segment to the student sequentially. | 2015-03-05 |
| 20150064665 | Write Start - Write Start is a device designed to help young students to hold a writing instrument correctly when learning how to write. The device consists of a stretchable pen or pencil holder that fits around the thumb and index finger. | 2015-03-05 |
| 20150064666 | LANGUAGE DELAY TREATMENT SYSTEM AND CONTROL METHOD FOR THE SAME - The present disclosures relates to a control terminal, comprising: a data communication unit for receiving a first user voice by data communication with a first audio device and receiving a second user voice by data communication with a second audio device; a turn information generating unit for generating turn information, which is voice unit information, by using the first and second user voices; and a metalanguage processing unit for determining a conversation pattern of the first and second users by using the turn information, and outputting a reminder message corresponding to a reminder event to the first user when the conversation pattern corresponds to a preset reminder event occurrence condition. | 2015-03-05 |
| 20150064667 | VISUAL TEACHING TOOL AND METHOD FOR DETERMINING THE RESULT OF DIGIT MULTIPLICATION BASED-ON DIAGRAM ROTATION AND TRANSITION PATH - A method for determining the result of digit multiplication based-on diagram rotation and transition path is proposed. Firstly, one of three types of visual teaching tools including first type of visual teaching tool, second type of visual teaching tool and third type of visual teaching tool is selected by a computing device. Then, the first type of visual teaching tool or the second type of visual teaching tool is rotated to determine an initial node by the computing device, and thereby transferring multiplicand from digit 1 to digits 3, 7, or 9, or transferring multiplicand from digit 2 to digits 4, 6, or 8. Finally, proceeding number (PN) of the first transition paths, the second transition paths or the third transition paths reaching to an object node is determined to obtain a multiplier and product value of the multiplicand and the multiplier by the computing device. | 2015-03-05 |
| 20150064668 | DYNAMIC OPERATOR BEHAVIOR ANALYZER - Dynamic industrial vehicle monitoring for modification of vehicle operator behavior comprises identifying a metric that characterizes an event associated with the operation of an industrial vehicle, the metric having at least one behavior modification action and at least one performance parameter to evaluate the event against. Monitoring operation of the industrial vehicle is carried out for the event. Upon detecting an occurrence of the event, event data is recorded that characterizes a response of a vehicle operator to the event. The recorded event data is evaluated against at least one performance parameter associated with the corresponding metric to determine whether the vehicle operator demonstrated appropriate behavior for the event. A vehicle operator score is updated based upon the evaluation and the updated vehicle operator score is communicated. | 2015-03-05 |
| 20150064669 | SYSTEM AND METHOD FOR TREATMENT OF EMOTIONAL AND BEHAVIORAL DISORDERS - A method for treating emotional and behavioural disorder includes using a sensor to obtain data pertaining to physiological responses of a user to an emotionally loaded sentence, to listed emotions, to listed chronological periods in the user's life, and to listed causes that may have led to absorption of an emotion during a period in the user's life. From the physiological response, an emotion having greatest emotional effect on the user, when it was absorbed, and its cause are determined. The user is presented with information associating the emotion, chronological period and cause. A sensor is used to obtain physiological data pertaining to the response of the user to a second instance of exposure to the emotionally loaded sentence. A result of treatment is determined by analysing and comparing the physiological data pertaining to the first and second exposures of the user to the emotionally loaded sentence. | 2015-03-05 |
| 20150064670 | DATA COLLECTION FOR VESTIBULOGRAM CONSTRUCTION - The methods, systems, and computer program products described herein enable the amount of information that can be acquired during a defined period of vestibular testing to be significantly increased while also significantly reducing the time required to collect data during such vestibular testing. These objects are achieved by intelligent data collection methods and systems configured to adaptively control a motion platform in a way that increases the amount of information gleaned from each data collection event and to achieve synergies based on the different types of, and the order of data analysis and calibration methods used. | 2015-03-05 |
| 20150064671 | METHODS AND SYSTEMS FOR MANAGING GOALS AND PROCESSING GOALS-RELATED DATA - Systems, methods and computer readable media for processing user-specified goals can include storing user accounts that are capable of directly linking to another, receiving and storing user-specified goals for each user account and associating proposed accomplishments including a value and unit of measurement, reminders and privacy and security settings. Also included are sending alerts at configurable time periods and providing advertising and rewards in accordance with the user-specified goals. Also included are displaying on a display device the user-specified goal data, progress graphs of user-specified goals for each user account node, and a status of obtaining a reward when a user-specified goal corresponds to one of the goals associated with the rewards. | 2015-03-05 |
| 20150064672 | SYSTEMS AND METHODS FOR TREATMENT OF SUBSTANCE ADDICTION - Systems and methods for treatment for addiction to a substance according to a predetermined action plan that includes a message control center for sending information to a messaging-accessible device associated with a user, an analyzer for analyzing an indicia of use of said substance, and a personalized treatment engine to receive an output from the analyzer and to direct the message control center based, at least in part, on the output from the analyzer and the predetermined action plan for the user. | 2015-03-05 |
| 20150064673 | BEHAVIORAL ORGANIZATION SYSTEMS - A motivational system for family organization and methods of using the system are described. The system allows for parents to assist children in fulfilling their responsibilities, setting and achieving goals, and learning values. The system is adaptable to each family's own value system and particular circumstances. Completion of tasks and progress towards goals is easily monitored by parents. The system uses a leveling system to categorize tasks and permits children to progress through levels of tasks. The system also possesses an integrated reward system to encourage task completion and progress towards goals while allowing children to have some choice in the rewards that they receive. | 2015-03-05 |
| 20150064674 | UNARMED COMBAT EXERCISE APPARATUS - This invention relates to apparatus for use in training students in unarmed combat, in particular the martial arts, and in methods of self-defence. It provides equipment, that can be in the form of a kit, comprising a visual marker that is detachably attached to an item of wearing attire for wearing in an unarmed combat training exercise or competition. When the attire bearing the attached marker is worn in use, the marker identifies, by its position on the attire, a body zone of the wearer that is to be targeted, in a training exercise or competition, by an opponent of the wearer. The wearer then endeavours to remove the marker from the garment, success indicating a successful strike at the target zone of the wearer's body. | 2015-03-05 |
| 20150064675 | RESPONSIVE TOOL WITH SENSORS - A flexible responsive surface of a tool is used on a tool (robotic or manual) that has a major surface and a sensor attached to and aligned with the major surface of the responsive tool. The sensor may have piezoelectric body, such as an elastic body containing conductive nanotubes homogeneously distributed therein to form a conductive path and at least two electrodes in electrical connection with the conductive path. Tools used in any surgical or medical treatment that are the subject of medical procedures are particularly useful in methods used in training personnel and evaluating medical techniques and medical personnel. | 2015-03-05 |
| 20150064676 | Interactive Educational System And Method - A system for associating an action of a user with a message corresponding to the action, where the message is visually displayed on a series of sequentially disposed discrete mats. The message is uttered by the user and the message is verified using a speech analyzer. The system includes at least two mats, each mat having a display, a transmitter, a receiver, and a presence sensor indicating the presence of the user and configured to indicate the intention of the user to add an answer to a composite answer. The system also includes an audio receiver that receives an audio input from the user and an indicator device that indicates whether the mat is a head mat. | 2015-03-05 |
| 20150064677 | SIMULATION BASED LEARNING SYSTEM AND METHOD FOR TRAINING AND SCORING ONE OR MORE CHALLENGES TAKEN BY A USER - A processor implemented method for scoring a challenge taken by a user, and training the user using a simulation based learning platform is provided. The processor implemented method includes (i) obtaining, from a database, challenges to be taken by a user and associated at least one of information, (iii) processing a selection of, the challenge from the challenges with actions or steps performed by the user, (iv) rendering, hints to solve the challenge, (v) recording, steps taken by the user to solve the challenge, (vi) comparing the steps taken by the user with steps taken by an expert to solve the challenge to compute a deviance of the user from a reference path, (vii) scoring, the challenge based on the deviance of the user from the reference path to obtain a score, and (viii) notifying, a result associated with the challenge to the user based on the score. | 2015-03-05 |
| 20150064678 | AUDIO COMMAND SYSTEM AND METHOD OF SUPERVISING WORKERS - An audio command system is provided which allows multiple sets of spoken instructions or commands to be stored in a digital memory and later broadcast to workers in various environments. The system includes a transducer, an analog-to-digital converter, and a voice memory. A control unit is provided for selecting a desired set of commands to be accessed from the voice memory and broadcast to the workers. A method of supervising workers using the audio command includes the steps of converting a plurality of sets of spoken commands into a plurality of sets of digital signals, storing each set of digital signals in a unique location in a memory device, selecting an operation to be performed, accessing the set of stored digital signals corresponding to the selected command set, converting the digital signals corresponding to the selected operation back into spoken commands, and broadcasting the spoken commands to the at least one worker. | 2015-03-05 |
| 20150064679 | MOBILE CLASS MANAGEMENT - An electronic system for providing assistance in teaching includes a teaching computer, a plurality of wireless tablets, a docking station arranged to receive the plurality of wireless tablets, a class configuration circuit, an educational content definition circuit, an educational session creation circuit, and an educational session management circuit. Also provided are a method performed by the system, a computer program for performing the above-specified method, and a storage medium including such a computer program. | 2015-03-05 |
| 20150064680 | METHOD AND SYSTEM FOR ADJUSTING THE DIFFICULTY DEGREE OF A QUESTION BANK BASED ON INTERNET SAMPLING - A system and method of providing a test may include generating, by a processor, a question having a difficulty coefficient. The processor may receive input from a participant answering the question. The processor may further measure a time for the participant to complete the question. The processor may determine whether or not to include the participant's input in adjusting the difficulty coefficient of the question, wherein said determination is based on the measured time. | 2015-03-05 |
| 20150064681 | SYSTEM FOR AUTOMATIC ASSESSMENT OF STUDENT LEARNING - A system for using a smartpen as a tool for automatically assessing student learning that is simple and accurate. The system has a computer with at least one processor, a memory, a storage, and communications through a protocol, one or more than one smartpen in communication with the computer and a plurality of software modules having non-transitory instructions executable on the processor for at least a characterization module, for characterizing spatial and temporal organization of a student's work, and a machine learning module utilizing the spatial and temporal organization to assess student learning. | 2015-03-05 |
| 20150064682 | SUPERVISION OF A MOBILE CLASS - A system for providing electronic assistance in teaching. The system includes a plurality of touch tablets (T | 2015-03-05 |
| 20150064683 | METHOD AND SYSTEM FOR GENERATING AND EVALUATING ASSESSMENT SHEETS - A method, a system, and a computer program product for creating and evaluating assessment sheets are disclosed. The method includes identifying one or more first location identifiers based on one or more markings provided in a scanned master assessment sheet. A machine-readable code (MRC) is generated based on the one or more first location identifiers. The MRC is then split into a plurality of portions and embedded at various locations on a scanned pre-assessment sheet. The scanned pre-assessment sheet with the embedded MRC is then printed to generate the assessment sheets. Thereafter, one or more second location identifiers are identified based on one or more markings provided by evaluatees in each of the assessment sheets provided to them. The one or more second location identifiers are then compared with the one or more first location identifiers. The result of evaluation is provided based on the comparison. | 2015-03-05 |
| 20150064684 | ASSESSMENT OF CURATED CONTENT - A method of assessing curated content may include receiving curated content. The method may also include assessing a quality of the curated content based on a predefined quality criteria and a selected template. The method may further include measuring user engagement with the curated content based on a predefined user engagement criteria. The method may also include generating a quality assessment result and a user engagement assessment result based on the assessed quality of the curated content and the measured user engagement of the curated content. | 2015-03-05 |
| 20150064685 | System and Method for Automatically Attaching a Tag and Highlight in a Single Action - A system and methods are disclosed for enabling users to attach a tag and highlight in a single action or activity to a select piece or portion of text in digital content (e.g., in a digital book or other content provided for viewing on an electronic device). In some implementations, the teacher may associate a tag with a particular text in the assignment, push the assignment embedding the tag to one or more students, and the tag becomes automatically visible to the one or more students through their highlight menu when they open up the assignment for completion. In some implementations, with this single activity, users may easily share tasks, comments etc., with ease. One or more other activities are also used among teachers and students to create and execute assignments with efficiency. | 2015-03-05 |
| 20150064686 | OXYGEN UPTAKE COMPOSITIONS AND PRESERVATION OF OXYGEN PERISHABLE GOODS - The preservation or extension of the life of oxygen perishable products such as fresh or cooked meats; fresh vegetables and fruits; dried vegetables, fruits and meats; packaged pharmaceuticals or biologicals; open and enclosed marketing display cases of meats, fruits and vegetables; and packaging, warehousing and transportation of meats, fruits, and vegetables is obtained by subjecting such products to an atmosphere obtained from gas permeable packets of an oxygen scavenging composition comprising a sodium carbonate mineral and one or more carboxylic acids. When the environment surrounding the oxygen perishable product is subjected to the packets of gaseous permeable oxygen scavenging compositions, oxygen is taken in by the scavenging composition and also the presence of carbon dioxide in the surrounding environment is enhanced thereby minimizing or eliminating the effect the oxygen on the oxygen perishable products. | 2015-03-05 |
| 20150064687 | Method and Apparatus for Producing Platelet Rich Plasma - A device and method for producing a portion of platelet rich plasma from a fluid sample obtained from a patient. The device comprises three intercommunicated portions, each portion having an internal chamber defined therein. The fluid sample is first brought into the base portion where it is separated into red blood cells and plasma. The plasma portion of the sample is then withdrawn into the second portion where it is further separated into platelet poor plasma disposed over platelet rich plasma. The portion of platelet poor plasma is then withdrawn from the second chamber, leaving only platelet rich plasma within the second chamber. The base portion also includes a membrane located on its distal end which helps maintain a vacuum within the device when the fluid sample is being initially inserted into base chamber. | 2015-03-05 |
| 20150064688 | METHOD OF MAKING A MICROFLUIDIC DEVICE - A microfluidic device allowing for multiple discrete reactions sites and allowing for sequential reactions and sample analysis along with methods for device fabrication and use is provided. The microfluidic device provides a micro-total analysis system on a single substrate and has multiple reaction sites allowing for cascade reactions and analysis on a single chip using micro-quantities of sample and reagents. The microfluidic device provides discrete sites for immobilization of cognitive agents including enzymes, binding proteins, nucleic acids and the like as well as methods for quantitative analysis. The invention also provides methods for the fabrication of the device. | 2015-03-05 |
| 20150064689 | SYSTEM AND METHOD FOR ANALYZING TRANSMISSIBILITY OF INFLUENZA - The present disclosure provides systems and methods for determining the transmissibility of a pathogen. The system described herein includes a flow device with a plurality of cell culture chambers. Cells, such as primary human tracheal or bronchial epithelial cells, are cultured within the flow device. Cells within a first cell culture chamber are infected with the pathogen. The pathogen's transmissibility is determined by flowing a gas through the flow device such that the gas flows over the infected cells and then over uninfected cells in a second cell culture chamber of the device. By quantifying the amount of virus present in the cells of the second cell culture chamber after a predetermined amount of time, the transmissibility of the pathogen is determined. | 2015-03-05 |
| 20150064690 | FACILE LABORATORY METHOD FOR LOCALISING BIOMOLECULES TO THE SURFACE OF CELLS AND VIRUSES - A facile method of localising sulfhydryl (—SH) group containing biomolecules, in particular peptides, to the membranes of living cells and enveloped viruses and a kit for use in a biological laboratory in accordance with the method. | 2015-03-05 |
| 20150064692 | IMMUNOCHROMATOGRAPHIC TEST STRIP AND DETECTION METHOD USING IMMUNOCHROMATOGRAPHY FOR DETECTING TARGET IN RED BLOOD CELL-CONTAINING SAMPLE - A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions. | 2015-03-05 |
| 20150064693 | SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES - Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample. | 2015-03-05 |
| 20150064694 | MULTIDIMENSIONAL HYDRODYNAMIC FOCUSING CHAMBER - Systems, including apparatus and methods, for the microfluidic manipulation, dispensing, and/or sorting of particles, such as cells and/or beads. The systems may include a shaped focusing chamber and/or a branched diverting mechanism. | 2015-03-05 |
| 20150064695 | METHODS FOR SCREENING AND DIAGNOSING GENETIC CONDITIONS - The present invention relates to methods and systems useful for screening and/or diagnosing genetic conditions in a fetus. | 2015-03-05 |
| 20150064696 | METHOD FOR DETECTING TARGET SUBSTANCE, ASSAY KIT, AND DETECTION APPARATUS - A method for detecting a target substance, provided by the present invention, is a method for detecting a target substance, characterized in that the method comprising the steps of: preparing a complex (hybrid) comprising an aptamer which binds to the target substance, a first nucleic acid fragment comprising a nucleotide sequence complementary to the aptamer and a photoisomerizable molecule bound to a portion of the complementary nucleotide sequence, wherein the aptamer and the first nucleic acid fragment bound with the photoisomerizable molecule form double-stranded nucleotides binding; subjecting the photoisomerizable molecule in the complex to a first photoisomerization treatment to destabilize the double-stranded nucleotides binding in the complex; forming a complex of the target substance and the aptamer so as to dissolve the destabilized double-stranded nucleotides binding in the complex (hybrid); subjecting the photoisomerizable molecule to a second photoisomerization treatment to restabilize double-stranded nucleotides binding in the complex; and detecting dissolution of double-stranded nucleotides binding wherein the first nucleic acid fragment bound with the photoisomerizable molecule separates from the aptamer. | 2015-03-05 |
| 20150064697 | P53 COOPERATION WITH DNA METHYLATION AND SUICIDAL INTERFERON RESPONSE TO CONTROL SILENCING OF REPEATS AND NCRNAS - Provided is a disclosure of methods involving determining RNA transcripts transcribed from repeats of polynucleotide sequences, the transcription of which are normally repressed by a combination of functional p53 and DNA methylation, and methods of detecting interferon, and determining constitutive activation of an interferon type I response. The methods permit identification of cancerous or precancerous cells, can identify non-functional p53, and provide therapeutic and prophylactic approaches for cancer. | 2015-03-05 |
| 20150064698 | METHOD FOR DETECTING TARGET NUCLEIC ACID USING MOLECULAR BEACON-TYPE PROBE - The present invention provides a detection system using a nucleic acid probe which is commonly used in a measurement system using a recombinase (e.g., nucleic acid amplification reaction). Specifically, the present invention provides a method for detecting a target nucleic acid, comprising measuring the target nucleic acid using a cleavage enzyme, a recombinase, and a probe having characteristics of the following (a) to (c): | 2015-03-05 |
| 20150064699 | APPARATUS FOR PHOTOMETRIC MEASUREMENT OF BIOLOGICAL LIQUIDS - An apparatus for photometric measurement of biological liquids and a method of simultaneously measuring the presence or quantity of an analyte in a sample region are disclosed. The apparatus includes a plurality of spaced apart sample regions; a light source adapted to emit light including at least one frequency; a lens system including a light coupling system, wherein the light coupling system is disposed between the light source and the plurality of sample regions. A method is also disclosed including illuminating the sample region with a light beam emitted from a light source, wherein said light beam passes a light coupling system, the light coupling system including a telecentric element and a plurality of light mixing rods, wherein the light coupling system is disposed between the light source and the sample region such that the light beam is directed into the sample region. | 2015-03-05 |
| 20150064700 | MARKERS FOR PRE-CANCER AND CANCER CELLS AND THE METHOD TO INTERFERE WITH CELL PROLIFERATION THEREIN - A novel family of human mitochondrial RNAs, referred to as chimeric RNAs, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the chimeric RNAs are provided. The described oligonucleotides or their analogs can be used for cancer diagnostics and cancer therapy as well as for research. In one embodiment of this invention, these oligonucleotides hybridize with the sense or with the antisense mitochondrial chimeric RNAs, and the result of the hybridization is useful to differentiate between normal proliferating cells, pre-cancer cells and cancer cells. In another embodiment of the invention, the compositions comprise oligonucleotides that hybridize with the human chimeric RNAs resulting in cancer cell and pre-cancer cell death, while there is no effect in normal cells, constituting therefore, a novel approach for cancer therapy. | 2015-03-05 |
| 20150064701 | METHODS AND KITS FOR PERFORMING IN SITU HYBRIDIZATION - The invention relates to methods and kits for performing in situ hybridization on a biological sample on a solid surface using nucleic acid probes that are embedded in or sorbed to a dry, fibrous matrix. | 2015-03-05 |
| 20150064702 | MICROFLUIDIC VALVE AND METHOD OF MAKING SAME - The present technology provides for a microfluidic substrate configured to carry out PCR on a number of polynucleotide-containing samples in parallel. The substrate can be a single-layer substrate in a microfluidic cartridge. Also provided are a method of making a microfluidic cartridge comprising such a substrate. Still further disclosed are a microfluidic valve suitable for use in isolating a PCR chamber in a microfluidic substrate, and a method of making such a valve. | 2015-03-05 |
| 20150064703 | RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING - Embodiments of various aspects described herein are directed to methods, compositions, kits and systems for rapid determination of antibiotic susceptibility of a microbe within hours after a sample is collected. In some embodiments, the methods, compositions, kits and systems described herein can allow determination of antibiotic susceptibility of a microbe based on a small number of microbes, e.g., as few as 5-10 microbes bound to a microbe-targeting substrate described herein. | 2015-03-05 |
| 20150064704 | COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR EARLY DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION - The present invention relates to non-invasive methods for early diagnosis and/or differential diagnosis of acute myocardial infarction in a blood sample of a subject. Further, the present invention relates to polynucleotides or sets of polynucleotides for detecting miRNAs or sets of miRNAs for early diagnosis and/or differential diagnosis of acute myocardial infarction in a blood sample of a subject. | 2015-03-05 |
| 20150064705 | DYE SETS FOR SURFACE ENHANCED RESONANT RAMAN SPECTROSCOPY - A kit for use in a multiplex assay, the kit including a dye set consisting essentially of a plurality of dyes and an association of each dye to a reference concentration. The dye set has been selected such that, using surface enhanced resonant Raman spectroscopy, each dye of the set is identifiable at better than 90% sensitivity and 90% specificity in the presence of any other dye of the set throughout a range of concentrations of each of the two dyes from 0.6 to 1.5 of the respective dye's reference concentration. In one embodiment, the dye set consists of 10 of the following dyes: JOE, Rhodamine Green, ATTO520, BODIPY FL, BODIPY TMR-X, FAM, HEX, Cy3, Cy3.5, TAMRA and TYE563. The invention also concerns a multiplex assay including the set of dyes, apparatus for carrying out the multiplex assay and a method of selecting the set of dyes. | 2015-03-05 |
| 20150064706 | Detection and Mixing in a Conduit in Integrated Bioanalysis Systems - Apparatuses and methods in which detection is integrated with various liquid processing and environmental control functions to create integrated bioanalysis systems are disclosed. Though the various integrated bioanalysis systems are useful for any number of analysis formats, they are adaptable to high-throughput processing of samples. | 2015-03-05 |
| 20150064707 | Molecular Diagnostics System and Methods - The present invention relates to methods for the extraction of nucleic acids from cells, the amplification of segments of nucleic acid and the detection of nucleic acids, all in a convenient and portable manner. In one embodiment, a sample comprising cells containing nucleic acid is exposed to an aqueous mixture comprising a lytic reagent and one or more beads capable of binding the nucleic acid released from said cells to form a nucleic acid-bead complex. The nucleic acid-bead complex is passed through an immiscible liquid layer to separate the nucleic acid from the aqueous mixture. The one or more beads are magnetic, and the nucleic acid-bead complex is passed through and separated from the immiscible liquid layer with an applied magnetic field. The invention is particularly suited for use in point-of-care medical diagnostics testing. | 2015-03-05 |
| 20150064708 | Rapid Targeting Assay in Crops for Determining Donor Insertion - The present disclosure provides methods for detecting and identifying plant events that contain precision targeted genomic loci, and plants and plant cells comprising such targeted genomic loci. The method can be deployed as a high throughput process utilized for screening a donor DNA polynucleotide insertion at the targeted genomic loci. The methods are readily applicable for the identification of plant events produced via a targeting method which results from the use of a site specific nuclease. | 2015-03-05 |
| 20150064709 | MODULATING GENE EXPRESSION WITH agRNA AND GAPMERS TARGETING ANTISENSE TRANSCRIPTS - Gene expression is selectively modulated in the genome of a mammalian cell determined to be in need thereof by determining the presence of an encoded antisense transcript overlapping a promoter of the target gene; contacting the transcript with an agRNA or gapmer complementary to a portion of the transcript upstream relative to the transcription start site of the gene; and detecting a resultant modulation of expression of the target gene. | 2015-03-05 |
| 20150064710 | METHOD FOR INHIBITING CELL GROWTH, NUCLEIC ACID MOLECULE HAVING RNA INTERFERENCE EFFECT ON NEK10 VARIANT GENE, AND ANTICANCER AGENT - The present invention provides a method for inhibiting cell growth, a nucleic acid molecule useful as an anticancer agent, and a method for screening novel anticancer agents. In the present invention, inhibitory effects on expression of NEK10 variant gene or inhibitory effects on activity of NEK10 variant protein are obtained in cells by transfecting cells with a nucleic acid molecule having an RNA interference effect on NEK10 variant gene. The present invention also provides a method for screening anticancer agents by using this inhibitory effect as an indicator. | 2015-03-05 |
| 20150064711 | ASSAY LABEL - This invention relates to an assay label comprising an amorphous carbon particle, a functionalised dextran polymer attached to the surface of the carbon particle and a first member of a complementary binding pair covalently bonded to the functionalised dextran polymer. The invention also provides a device incorporating the assay label, which further comprises a radiation source adapted to generate a series of pulses of electromagnetic radiation at a wavelength such that the absorption of the radiation by the label generates energy by non-radiative decay; a sample chamber containing a transducer having a pyroelectric or piezoelectric element and electrodes which is capable of transducing energy generated by non-radiative decay into an electrical signal; and a detector which is capable of detecting the electrical signal generated by the transducer. | 2015-03-05 |
| 20150064712 | ANALYTIC PLATES WITH MARKABLE PORTIONS AND METHODS OF USE - An analytic plate or other substrate having a permanent etchable, laserable, and/or developable marking surface coating (referred to herein as an “etchable coating” or as a “developable coating”) that is present on at least a portion of any side or surface thereof and is used to deposit a permanent indicium thereon, and a method of using the analytic plate or substrate. | 2015-03-05 |
| 20150064713 | METHODS, KITS AND MEANS FOR DETERMINING INTRACELLULAR INTERACTIONS - Methods, kits and systems for determining whether a reaction occurs between a chimeric transmembrane receptor and an intracellular interaction partner thereof within a cell. | 2015-03-05 |
| 20150064714 | Polypeptides containing a modified fragment of the peptide IF1 - Labelled polypeptide constituted by:
| 2015-03-05 |
| 20150064716 | Goodpasture Antigen Binding Protein and Its Detection - The present invention provides native Goodpasture antigen binding protein isoforms, monoclonal antibodies directed against such proteins, and methods for their use. | 2015-03-05 |
| 20150064717 | METHOD FOR STAINING TISSUE - Provided is a method for staining a tissue enabling highly precise staining, by which the expression amount and/or the location of a biological substance in a tissue sample can be detected with a high quantitativity together with detailed information that can be obtained by bright field observation. | 2015-03-05 |
| 20150064718 | ORGANIC/INORGANIC MAGNETIC COMPOSITE, METHODS OF MAKING AND USE THEREOF - An organic/inorganic composite is provided. The organic/inorganic composite materials are sufficiently hard and brittle to be ground to form particles suitable for biological or chemical separation applications. The organic/inorganic composite materials can be magnetic or magnetically susceptible and can have functional reactive groups to allow attachment of biomolecules. Methods of making and using the organic/inorganic composites are also provided. | 2015-03-05 |
| 20150064719 | INTEGRITY TESTING OF HAIR SAMPLES - Methods for assessing the condition of keratinized structures, including hair, in particular methods to determine the condition of keratinized structures in relation to suitability for analysis of analytes of interest in a test sample, are presented. The methods comprise contacting the keratinized structure with a non-proteolytic reducing agent and an optional proteolytic agent. The methods further include inspection of the hair sample, or measurement of free protein eluted from the keratinized structure, after reduction and optional proteolysis to determine condition prior to analyte identification and quantitation by known techniques such as immunoassays. | 2015-03-05 |
| 20150064720 | BIOMOLECULE-GRAPHENE QUANTUM DOT CONJUGATES AND USE THEREOF - The invention relates to biomolecules conjugated to graphene quantum dots, and in particular, to use of such biomolecule-graphene quantum dot conjugates as fluorophores for imaging applications. | 2015-03-05 |
| 20150064721 | COMPOSITION AND KIT FOR SEPARATING CANCER CELL, AND METHOD OF SEPARATING CANCER CELL BY USING THE COMPOSITION AND KIT - Provided is a composition and a kit for separating a cancer stem cell or a circulating tumor cell, a method of separating a cancer stem cell or a circulating tumor cell in a biological sample, and a method for diagnosing metastatic cancer. | 2015-03-05 |
| 20150064722 | METHOD FOR DETECTING THE DEGREE OF MALIGNANCY OF EACH OF THE CIRCULATING TUMOR CELLS, AND A KIT FOR THE SAME - The object of the present invention is to provide an evaluation method capable of accurately determining a metastasis of cancer, the stage of cancer progression, or the malignancy of cancer. | 2015-03-05 |
| 20150064723 | DUAL MODE SENSOR - A novel dual mode sensor may combine mass-sensing measurements of dynamic-mode cantilevers with electrochemical impedance spectroscopy employed for transduction in sensitive electrochemical biosensors. The integrated design of the sensor may provide simultaneous and continuous measurement of resonant frequency shift and charge transfer resistance of a target analyte bound to a surface of the sensor. Binding of a target analyte to the surface of the sensor may cause charge transfer resistance to increase and the resonant frequency of the sensor to decrease. These simultaneous dynamic modes of the sensor may be utilized to measure an amount of mass of the target analyte accumulated on the surface of the sensor and to reduce and/or eliminate false negative measurement results. | 2015-03-05 |
| 20150064724 | BIOMARKERS FOR PROGNOSES OF PULMONARY DISEASES - The present invention relates to biomarkers that may be used to evaluate the prognoses of patients suffering from pulmonary diseases and assist in the determination of appropriate therapeutic regimens. It is based, at least in part, on the discovery that a number of T-cell antigens are differentially expressed in chronic lung disease patients depending on the prognosis of the patient. Non-limiting examples of these antigens include CD28, CD4, CD25, CD45, CD27 and CCR7 and combinations thereof. Use of these biomarker antigens, optionally in conjunction with pulmonary function tests, provides an indication of which patients are likely to suffer a severely adverse outcome within the year and/or be refractory to treatment. | 2015-03-05 |
| 20150064725 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful for production of proteins. | 2015-03-05 |
| 20150064726 | Biochemical Markers for Neurodegenerative Conditions - A method of bioassay for the quantification of peptide fragments relevant to neurodegenerative conditions comprising a neo-epitope formed by cleavage of a Tau protein by a secretase such as ADAM10 comprises contacting a blood derived sample with an antibody specific for the neo-epitope and determining the level of binding of said immunological binding partner to peptide fragments in said sample. Neo-epitope containing peptide levels are found to be inversely correlated to cognitive function. | 2015-03-05 |
| 20150064727 | Ectoparasite Detection - Ectoparasite infestation of a substrate like bedding is detected by contacting a sample from the substrate with a polyclonal ectoparasite antibody generated from a whole ectoparasite immunogen, under conditions wherein the antibody specifically binds ectoparasite antigen in the sample. | 2015-03-05 |
| 20150064728 | PROCESS FOR DETERMINING THE SUSCEPTIBILITY TO NOSOCOMIAL INFECTIONS - The invention relates to a process for determining the susceptibility to nosocomical infections in a patient, comprising the measurement of the expression of sCD127 in a biological sample. | 2015-03-05 |
| 20150064729 | METHOD AND KIT FOR IMMUNOLOGICAL DETECTION OF MYCOBACTERIUM TUBERCULOSIS - Definitive diagnosis and early start of treatment cannot be made for tuberculosis since conventional methods for detecting a | 2015-03-05 |
| 20150064730 | Methods and Devices for Rapid Assessment of Severity of Injury - Methods and devices for rapid assessment of the severity of injury not due to a natural disease based upon measurement of neutrophil gelatinase-associated lipocalin (NGAL) are provided. | 2015-03-05 |
| 20150064731 | OPLOPHORUS-DERIVED LUCIFERASES, NOVEL COELENTERAZINE SUBSTRATES, AND METHODS OF USE - The present invention provides, among other things, imidazo[1,2-α]pyrazine derivatives according for Formula (Ia) or Formula (Ib). The derivatives are useful in any method which other coelenterazines have been used. For example, the derivatives may be used in a bioluminogenic method to detect the presence of certain compounds or molecules. | 2015-03-05 |
| 20150064732 | Analytical Test Cartridge; and, Methods - An analytical test cartridge is provided. The analytical test cartridge can be used for medical analyses of liquid samples removed from a patient, for example blood. The analytical test cartridge is configured to provide for titration experiments. An example of a titration experiment that can be performed with the arrangement, is titration of heparin with protamine. Methods of assembly and use are provided. | 2015-03-05 |
| 20150064733 | GLYCOSYLATED MODIFIED FLAVIN ADENINE DINUCLEOTIDE-DEPENDENT GLUCOSE DEHYDROGENASES, COMPOSITIONS THEREOF AS WELL AS METHODS OF MAKING AND USING THE SAME - Compositions, devices, kits and methods are disclosed for assaying glucose with a glycosylated, modified flavin adenine dinucleotide-dependent glucose dehydrogenase (FAD-GDH), variant thereof or an active fragment thereof, where at least one asparagine residue at positions N2, N168 and N346 of mature, wild-type | 2015-03-05 |
| 20150064734 | METHOD FOR SCREENING THERAPEUTIC AND/OR PROPHYLACTIC AGENTS FOR ALZHEIMER'S DISEASE - The present invention provides a method for screening a therapeutic and/or prophylactic agent for Alzheimer's disease using at least one index selected from the group consisting of the levels of Aβ oligomers, BiP, cleaved caspase 4, PRDX4 and ROS in nerve cells or the like whose differentiation has been induced from iPS cells derived from somatic cells of a patient with Alzheimer's disease. | 2015-03-05 |
| 20150064735 | METHOD FOR THE DETERMINATION OF SEQUENCE VARIANTS OF POLYPEPTIDES - The current invention is directed to a method for determining amino acid sequence mutations in a produced polypeptide, comprising the following steps of a) providing a sample of a produced polypeptide, b) incubating the polypeptide in the sample with a protease, c) performing a two dimensional analysis using reversed phase chromatography coupled with a high resolution mass spectroscopy (FT-ICR/FT-orbitrap) and MS/MS analysis of the amino acid sequence fragments of the peptides, d) data evaluation by comparing the LC-MS data sets obtained for the samples side by side with the data set of a reference sample, by searching for differences in the signal intensities at given retention times and by evaluation of differential signals with respect to amino acid sequence mutations. The reference sample for data evaluation (d) can be either a well characterized standard or one of the samples to be analyzed. | 2015-03-05 |
| 20150064736 | NOVEL 2,5-DIKETO-L-GLUCONIC ACID REDUCTASES AND METHODS OF USE - Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described. | 2015-03-05 |
| 20150064737 | IMAGING APPARATUS AND IMAGING METHOD - An imaging apparatus for imaging a two-dimensional image of an imaging object comprises a holder which holds a sample container carrying a biological sample as the imaging object on a carrying surface, a light emitting part which emits light toward the carrying surface, an imager which includes a strip-like light receiving part, receives the light incident on the light receiving part and thereby images an image of a strip-like region of the carrying surface, a strip-like light shield which shields a part of light emitted from the illuminator toward the strip-like region, and a mover which integrally and relatively moves the light emitting part, the light receiving part and the light shield with respect to the sample container. | 2015-03-05 |
| 20150064738 | CULTURE VESSEL FOR FORMING AGGREGATED CELL MASS - The present invention provides a culture vessel for forming an aggregated cell mass which has at least two wells, wherein the wells are made from a light-shielding member and an inner surface of the wells is subjected to treatment to impart cellular non-adhesiveness. | 2015-03-05 |
| 20150064739 | ANALYZER - An analyzer includes a pretreatment device and a mass spectrometer. The pretreatment device includes a solid phase extraction mechanism. The mass spectrometer performs mass spectrometry on a sample pretreated by the pretreatment device and then subjected to ionization. The analyzer also includes a storage unit that stores data on dependence of signal intensities of the analyte substance to be measured and the internal standard upon the concentration of a substance inhibiting ionization in the sample, and that stores data on a recovery rate. The analyzer also includes a correcting unit that corrects measurement results of the sample and the internal standard on the basis of the data stored in the storage unit. | 2015-03-05 |
| 20150064740 | SPECIMEN PROCESSING APPARATUS - The present invention is to present a specimen processing apparatus, comprising: an imaging device for imaging a cap of a covered specimen container containing a specimen; an aspirating device including a specimen aspirating tube, moving the specimen aspirating tube so as to pass the specimen aspirating tube through the cap of the covered specimen container and aspirating the specimen contained in the covered specimen container via the specimen aspirating tube; an aspiration controller for controlling a movement of the specimen aspirating tube into the covered specimen container based on an image obtained by the imaging device; and a specimen processing device for processing the specimen aspirated by the aspirating device. | 2015-03-05 |
| 20150064741 | METAL WORKING FLUID COMPOSITION AND METHOD OF DETECTING FLUID DETERIORATION - A wear-indicating metalworking fluid is provided that includes a lubricant base; and a wear-indicating agent. A method of determining wear in a metalworking fluid includes providing wear-indicating metalworking fluid that contains a lubricant base and a wear indicating agent; and observing the visual appearance of the metalworking fluid. A change in visual appearance of the metalworking fluid when compared to an unused metalworking fluid indicates wear of the metalworking fluid. | 2015-03-05 |
| 20150064742 | SAMPLE ANALYZING METHOD AND SAMPLE ANALYZER - Disclosed is a sample analyzing method comprising: flowing a measurement specimen prepared by mixing a sample and reagent through a flow cell; irradiating particles in the measurement specimen flowing through the flow cell with linearly polarized light and thereby producing scattered light; detecting a change of polarization condition of the scattered light produced by the particles; and discriminating erythrocytes from crystals in the measurement specimen based on the change of polarization condition. | 2015-03-05 |
| 20150064743 | Methods and Materials for Biosynthesis of Mogroside Compounds - The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention. | 2015-03-05 |
| 20150064744 | MODIFIED ENTEROKINASE LIGHT CHAIN - The present invention is related to novel mammalian enterokinase analogues such as mammalian enterokinase light chain analogues and methods of making such. Also described herein is a method for cleaving proteins having an enterokinase cleavage site. | 2015-03-05 |
| 20150064745 | METHOD FOR PRODUCING PROTEIN BY PRECIPITATION - The present invention provides a method for producing a target protein in the form of a fusion protein at a high recovery ratio. The present invention relates to a method for producing a fusion protein made of a protein having a self-assembly capability and a target protein comprising the following steps (1) to (4):
| 2015-03-05 |
| 20150064746 | METHOD FOR REDUCTION OF 1->3 READING FRAME SHIFTS - Herein is reported a method for the recombinant production of a polypeptide, which comprises the tripeptide QKK, characterized in that the method comprises the step of recovering the polypeptide from the cells or the cultivation medium of a cultivation of a cell comprising a nucleic acid encoding the polypeptide and thereby producing the polypeptide, whereby the tripeptide QKK comprised in the polypeptide is encoded by the oligonucleotide cag aaa aaa or the oligonucleotide caa aag aaa. | 2015-03-05 |
| 20150064747 | MODIFIED EPSTEIN-BARR VIRUS DNA POLYMERASE AND METHODS FOR ISOTHERMAL DNA AMPLIFICATION - Modified Epstein Barr Virus DNA polymerase for use in nucleic acid amplification, including isothermal nucleic acid amplification, in vitro are provided. Methods using and kits comprising Epstein Barr Virus DNA polymerase and its variants of this invention for nucleic acid amplification in vitro, including isothermal DNA amplification, are also provided. | 2015-03-05 |
| 20150064748 | PROCESS FOR PRODUCING APLHA-1,3-GLUCAN POLYMER WITH REDUCED MOLECULAR WEIGHT - A process for producing poly alpha-1,3-glucan with reduced molecular weight is disclosed. The process comprises contacting water, sucrose, a polar organic solvent, and a glucosyltransferase enzyme in a solution to produce poly alpha-1,3-glucan. This contacting step results in the production of poly alpha-1,3-glucan having a reduced molecular weight compared to the molecular weight of a poly alpha-1,3-glucan made in the absence of the polar organic solvent. | 2015-03-05 |
