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10th week of 2015 patent applcation highlights part 51
Patent application numberTitlePublished
20150064046TI/TIC COMPOSITE, PRODUCTION METHOD AND USE THEREOF - The present invention provides a Ti material extremely high in mechanical strength. A Ti/TiC composite, wherein no simple substance of carbon essentially exists in a TiC, and wherein 0.3 mass % or more of oxygen is solidified in the composite. A Ti/TiC composite has an upper yield point in a relation between a tensile strength and an elongation.2015-03-05
20150064047SYSTEMS AND METHODS FOR ADDITIVE MANUFACTURING OF THREE DIMENSIONAL STRUCTURES - A method of fabricating a three dimensional structure includes delivering a metal material to a printing site; and defining a microstructure of the metal material at the printing site by controlling the delivery of heating energy to the printing site and controlling the delivery of ultrasonic vibrations to the printing site.2015-03-05
20150064048METHOD AND APPARATUS FOR PRODUCING THREE-DIMENSIONAL OBJECTS WITH IMPROVED PROPERTIES - Method for fabricating a three-dimensional object by successive consolidation, layer by layer, of selected regions of a layer of powder, consolidated regions corresponding to successive sections of the three-dimensional object, comprising in order: 2015-03-05
20150064049METHOD AND APPARATUS FOR SEPARATING A CANISTER AND COMPONENT - A method and apparatus for removing a canister 2015-03-05
20150064050MULTIPLE COIL ARRANGEMENT FOR A DEVICE FOR GENERATIVE PRODUCTION OF COMPONENTS AND CORRESPONDING PRODUCTION METHOD - A device for additive manufacturing of components by selective irradiation of a powder bed, having a processing chamber -in which at least one powder bed chamber and at least one radiation source are arranged such that the radiation source can irradiate a powder in the powder bed chamber, and wherein the device includes at least one induction coil, so that a component which is produced by irradiation of the powder bed can be at least partially inductively heated, and wherein the induction coil is movable relative to one or more powder bed chambers. A method for additive manufacturing of components by selective irradiation of a powder bed, in which method the component being manufactured is inductively heated at the same time, wherein the position of one or more induction coils for inductive heating is determined and adjusted based on the geometry of the component to be produced.2015-03-05
20150064051EMBOSSMENT STRUCTURE FORMED IN A MOLD AND ITS MANUFACTURING METHOD - A manufacturing method of an embossment structure formed in a mold in the present invention is applicable to plastic or metallic in-mold shaping products, such as computers, communication products, consumer electronic products, electrical appliances, parts of machines and instruments or common household products. A base layer provided with embossment structure or tri-dimensional ornament and a separable layer is stably fixed in a shaping mold by making use of absorption mode of the shaping mold. After shaped completely, the base layer on the surface of the in-mold shaping product is torn off to present delicate tri-dimensional embossed streaks on the surface of the in-mold shaping product, which is designed according to personalization or individuation, able to lower cost and increase external beauty of the in-mold shaping product and conform to economic gain.2015-03-05
20150064052WARM PRESS FORMING METHOD AND AUTOMOBILE FRAME COMPONENT - A method of forming a steel sheet having a tensile strength of 440 MPa or more into a press-formed part including a flange portion and other portions by press forming includes: heating the steel sheet to a temperature of 400° C. to 700° C.; and press-forming the heated steel sheet using draw forming to obtain a press-formed part, with the steel sheet being held at a press bottom dead point in the die for one second to five seconds. Geometric changes such as springback that occur in a panel can thus be suppressed, the dimensional accuracy of the panel can be enhanced, and the desired mechanical properties can easily be obtained in the press-formed part.2015-03-05
20150064053PSEUDOELASTIC MAGNESIUM ALLOY, PSEUDOELASTIC MAGNESIUM ALLOY COMPONENT, AND PRODUCTION METHOD THEREOF - A pseudoelastic magnesium alloy contains magnesium as the main component thereof, and at least one element selected from Sc, Y, La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu, wherein the pseudoelastic magnesium alloy has a unidirectional crystal structure.2015-03-05
20150064054IMPLANT MADE OF A BIODEGRADABLE MAGNESIUM ALLOY - An implant made in total or in parts of a biodegradable magnesium alloy consisting of Y: 2.0-6.0% by weight, Nd: 1.5-4.5% by weight, Gd: 0-4.0% by weight, Dy: 0-4.0% by weight, Er: 0-4.0% by weight, Zr: 0.1-1.0% by weight, Li: 0-0.2% by weight, Al: 0-0.3% by weight, under the condition that a) a total content of Er, Gd and Dy is in the range of 0.5-4.0% by weight and b) a total content of Nd, Er, Gd and Dy is in the range of 2.0-5.5% by weight, the balance being magnesium and incidental impurities up to a total of 0.3% by weight.2015-03-05
20150064055TITANIUM ALLOY FOR GOLF CLUB FACE - An α+β-type titanium alloy which, has a high Young's modulus and strength-ductility balance is provided as a material for a face of a driver, iron, or other golf club.2015-03-05
20150064056TANTALUM SPUTTERING TARGET, METHOD FOR MANUFACTURING SAME, AND BARRIER FILM FOR SEMICONDUCTOR WIRING FORMED BY USING TARGET - Provided is a tantalum sputtering target, which is characterized that an average crystal grain size of the target is 50 μm or more and 200 μm or less, and variation of a crystal grain size in the target plane is 40% or higher and 60% or less. This invention aims to provide a tantalum sputtering target capable of improving the uniformity of the film thickness and reducing the variation of the resistance value (sheet resistance).2015-03-05
20150064057METHODS FOR PRODUCING NIO NANOPARTICLE THIN FILMS AND PATTERNING OFNI CONDUCTORS BY NIO REDUCTIVE SINTERING AND LASER ABLATION - A method for producing a nickel-containing surface coating that is metallic and conductive is provided. The method includes contacting a surface of a substrate with a liquid composition that includes nickel oxide nanoparticles, and modifying the nickel oxide nanoparticles to produce a nickel-containing metallic and conductive surface coating on the surface of the substrate. Also provided are nickel-containing (e.g., NiO and Ni containing) surface coatings and methods for making a liquid composition that includes nickel oxide nanoparticles. The methods and compositions find use in a variety of different applications.2015-03-05
20150064058Method Of Manufacturing Aluminum-Zinc-Based Alloy Sheet Using Twin-Roll Casting And Aluminum-Zinc-Based Alloy Sheet Manufactured Thereby - Provided are a method of manufacturing an aluminum-zinc-based alloy sheet using twin-roll casting and an aluminum-zinc-based alloy sheet manufactured thereby. Specifically, a method of manufacturing an aluminum-zinc-based alloy sheet, including preparing a melt by melting elements corresponding to an aluminum alloy including 0.5 wt % to 10 wt % of zinc, inevitable impurities and aluminum as a balance (step 1); and twin-roll casting by introducing the melt prepared in step 1 between a pair of rotating cooling rolls (step 2), and an aluminum-zinc-based alloy sheet manufactured thereby are provided.2015-03-05
20150064059PROCESS FOR PRODUCING CAST-METAL OBJECT, AND CAST-METAL OBJECT - Occurrence of a casting defect in a cast-metal object is suppressed, and a crystal structure of the cast-metal object is made fine. When a cast-metal object is to be produced by using a casting mold, a metal material generating a free crystal during solidification is melted first. Subsequently, a molten metal including a melted metal material is poured into the casting mold. While the free crystal in the molten metal is deposited on a surface of the casting mold, the molten metal is solidified in the casting mold. Through the above steps, the molten metal is solidified in the casting mold, and the cast-metal object is produced.2015-03-05
20150064060Scented windshield washer fluid - The invention provides and improved way to provide air freshener, scent, fragrance or perfume to an automobile in a milder and evenly applied manner. The additive or premixed fluid is combined with windshield washer fluid. Where it may be dispensed or applied on the exterior of the windshield. Where by it is pulled from the outside of the car and vented into the automobile, for use as and interior air freshener.2015-03-05
20150064061Air Purifier for Transportation Vehicles - A vehicle air purification system has a photocatalyst activated by photons emitted via an ultraviolet light emitting diode (UV-LED). The photocatalyst on a supporting structure is positioned to contact airflow passing through or over the photocatalyst. Chemical contaminants and microorganisms are eliminated from the airflow that makes contact with the photocatalyst structure.2015-03-05
20150064062METHOD AND APPARATUS FOR THE STERILIZATION OF CONTAINERS WITH CLEANING OF A RADIATION OUTLET WINDOW - A method of operating an apparatus for the sterilization of plastics material containers is provided, wherein charge carriers are generated in a working operation and are conveyed through a guide chamber and emerge from this guide chamber by way of an outlet window bounding this guide chamber and wherein the outlet window is introduced into the plastics material containers at least in part through an aperture of the aforesaid plastics material containers during the sterilization of the plastics material containers. The outlet window is acted upon with a flowable cleaning medium in a cleaning operation of the apparatus.2015-03-05
20150064063APPARATUSES AND METHODS FOR CLEANING AND DRYING PROSTHETIC LINERS - Apparatuses are provided that eliminate microbes in a prosthetic liner. Apparatuses are provided that eliminate odors and moisture from a prosthetic liner. Apparatuses and methods disclosed illuminate prosthetic liners with anti-microbial lights and push air past the prosthetic liners.2015-03-05
20150064064MOBILE DISINFECTOR USING UV LED - A mobile disinfector using UV LEDs can include: a case forming an exterior structure of the disinfector; a cover including two parts coupled to respective sides of the case and including openings formed on the cover; and LED units exposed to outside through the openings formed on the cover. Since the cover is coupled to the case such that an angle between the cover and the case is adjusted, an irradiation angle of light emitted to the outside from the LED units is controlled.2015-03-05
20150064065ULTRAVIOLET AUTONOMOUS TROLLEY FOR SANITIZING AIRCRAFT - A mobile body is configured to travel over a surface inside an aircraft cabin. A source of UV radiation is mounted to the mobile body and configured to direct UV radiation to the surface at a predetermined dosage. At least two articulated arms are mounted to the mobile body, and UV lamps mounted respectively on the arms. The mobile body is a trolley or cart for negotiating an aircraft aisle.2015-03-05
20150064066ROOM FOGGING DISINFECTION SYSTEM AND METHOD - A method for disinfecting a room includes generating a fog from an enclosure having first and second air inlets and an air dispersion outlet including a fan configured to draw air into the enclosure through first and second air inlets and to force air out of the enclosure. A filter assembly is disposed relative to the second air inlet such that air that flows between the exterior and interior of the enclosure through the second air inlet passes through the filter assembly. The method further includes actuating an air intake assembly, activating the fan, actuating the air intake control assembly, and deactivating the fan.2015-03-05
20150064067METHOD OF PERFORMING STERILIZATION CYCLE - A method of sterilizing articles, using a low-vapor-pressure sterilant in a compact sterilizer, including a pre-pulse injection of sterilant to condition a sterilization chamber.2015-03-05
20150064068DEVICES FOR DETERMINING PHOTOPROTECTIVE MATERIALS - This invention provides methods and apparatus for quantification of photoprotective performance of packaging concepts in an accelerated timeframe. In certain embodiments, the apparatus comprises a light source which provides a light beam that impinges upon a photoprotective material before being transmitted to a sample cell comprising a photosensitive entity, such as a photosensitive nutrient. In certain embodiments, the apparatus and methods can be used to generate models for the prediction of photoprotective performance values of untested materials based upon some other known qualitative or quantitative property.2015-03-05
20150064069AIR PURIFIER USING ULTRAVIOLET RAYS - An air purifier includes a case having an air inlet and an air outlet, a fan disposed adjacent the air inlet, a UV LED unit and a filter unit arranged over the fan along a flow path of air, and a fluid control structure disposed between the fan and the filter unit.2015-03-05
20150064070CATALYST FILLING APPARATUS OF BUBBLE COLUMN SLURRY BED REACTOR AND CATALYST FILLING METHOD OF BUBBLE COLUMN SLURRY BED REACTOR - A catalyst filling apparatus is for a bubble column slurry bed reactor for the FT synthesis reaction. The apparatus includes: a slurry preparation tank installed adjacent to the reactor and configured to prepare a slurry S from a FT synthesis reaction catalyst and a slurry preparation oil; an upper part communication line configured to direct the slurry from the reactor to the slurry preparation tank; a lower part communication line configured to direct the slurry in the slurry preparation tank to the reactor; and a pressure equalizing line configured to communicate the reactor with the slurry preparation tank. The upper part communication line is downwardly inclined from the reactor toward the slurry preparation tank, and the lower part communication line is upwardly inclined from the reactor toward the slurry preparation tank. An inert gas introduction device is provided on the slurry preparation tank.2015-03-05
20150064071Disposable Module For Device For Synthesizing Radioisotopes And Process For Manufacturing Said Module - The present invention relates to a disposable module (2015-03-05
20150064072Emissions Cleaning Module - An emissions cleaning module is provided including a first support, a second support and a mixer module. The mixer module extends between the first support and the second support. The mixer module includes an outer body and an inner body located within the outer body. In addition the outer body is fixedly retained to the first support and the second support. Further, a first end of the inner body is slidingly retained within the outer body, and a second end of the inner body is fixedly retained relative to the outer body at or near the second support.2015-03-05
20150064073HEATING DEVICE - The objective of the present invention is to reduce the loss in functionality due to the burn-out of micro-coils in a heating device, which uses micro-coils formed of carbon or molecules that include carbon as a principal component for heating a target object located in a space where high-temperature gases flow. The present invention relates to a heating device comprising: a heat producing layer having a micro-coil formed of carbon or molecules that include carbon as a principal component, where the heat producing layer is installed together with the target object located in a target space where high-temperature gases flow; and an electromagnetic (EM)-wave-emitting device that emits EM radiation into the target space. The target object is heated by producing heat in the micro-coil by EM radiation from the EM wave emitting device emitted to the target space. The heating device further comprises a covering layer, which coats the entirety of the heat producing layer.2015-03-05
20150064074ZEIOLITE CATALYST CONTAINING METAL - A catalyst composition is provided wherein the composition includes a zeolite having a non-phosphorous CHA crystal structure and having a mean crystalline size of about 1 to about 5 microns; and at least one non-aluminum base metal present in an amount sufficient to achieve a NOx conversion of at least about 65% at a temperature of at least 450° C.2015-03-05
20150064075ENVIRONMENTAL SANITIZER AND ODOR REMOVER FOR PURIFICATION OF FOODS, SURFACES, AIR AND WATER WITH DISPOSABLE OZONE GENERATION ELECTRODE, PRESSURE/FLOW ADAPTABLE VENTURI INJECTOR AND AQUEOUS PHASE FILTER DEVICE - A dielectric assembly for generating ozone includes a positive electrode, a negative electrode, a dielectric for generating the ozone, and a knob adapted to extend outside of a housing into which the dielectric assembly is to be placed. A system is also provided for sanitizing and deodorizing water, food, surfaces and air including a microbiological reduction filter device having an input connected to a water supply, a venturi injector disposed within a housing and connected to an output of the microbiological reduction filter device which generates ozone and mixes the generated ozone with the water, and an electrode assembly comprising a plurality of electrodes, a dielectric for generating the ozone, and a knob extending outside of the housing. The dielectric in a first embodiment and the entire dielectric assembly in a second embodiment can be removed from the housing and replaced in its entirety by the knob.2015-03-05
20150064076PROCESS AND APPARATUS FOR PRODUCING DIESEL WITH HIGH CETANE - A process and apparatus is provided to produce desulfurized diesel at low pressure with high cetane rating. A hydrotreated stream is stripped and fed to a saturation reactor. The saturated stream is stripped again and fractionated to provide diesel product. Unconverted oil may be hydrocracked and stripped with the saturated product.2015-03-05
20150064077Method of Manufacturing Bio-Diesel and Reactor - A reactor and process for the production of bio-diesel. The reactor includes one or more coiled reaction lines. The lines are positioned within a tank containing a heat transfer media such as molten salt, maintained at about 750° F. A pump circulates the media within the tank. An emulsion of alcohol; refined feed stock, including glycerides and/or fatty acids; and preferably water is pumped through the reaction lines at temperatures and pressures sufficient to maintain the alcohol in a super-critical state. The curvature of the coils, pump pulsing, and the flow rate of the emulsion keep the emulsion in a turbulent state while in the reactor, ensuring thorough mixing of the alcohol and feed stock. The alcohol reacts with the glycerides and fatty acids to form bio-diesel. The reaction is fast, efficient with regard to energy input and waste generation, and requires minimal alcohol.2015-03-05
20150064078PROCESS FOR PERFORMING AN ENDOTHERMIC REACTION - Process for performing an endothermic reaction in a reactor containing catalyst tubes, the catalyst tubes containing a catalyst promoting the endothermic reaction, the process comprising the steps of, 2015-03-05
20150064079CATALYST SUBSTRATE MODULE FOR EXHAUST AFTERTREATMENT SYSTEM - A catalyst substrate module for an exhaust aftertreatment system is provided. The catalyst substrate module comprises an outer containment wall, an inner containment wall, a first bar, a second bar, a first substrate element, a second substrate element, and a center member. The outer containment wall and the inner containment wall are co-planar and aligned along a common centerline. The first bar and the second bar are coupled to an inner face of the outer containment wall. The first substrate element is enclosed within an inner face of the inner containment wall and the second substrate element is captured within a space defined by the inner containment wall and the outer containment wall. Further, the center member extends along the centerline of the inner containment.2015-03-05
20150064080SALIVA CONTAINER WITH OPTICAL VOLUME INDICATOR - A device with a vessel for saliva that has one or more optical indicators to show the volume of saliva in the container. The optical indicators use the principle of total internal reflection together with the difference in refractive index between saliva and air. In embodiments, suitable visual indicators are either visible or invisible, when reflecting surfaces are either not immersed or immersed in saliva or vice versa. The device may comprise a vessel with a saliva pathway, a saliva containment region defining a saliva reservoir, the reservoir having a desired fill level, and an optical viewing window adjacent an angled reflective surface for level indication and/or validating a fill level. The device may include patient interface components and chemical test strips.2015-03-05
20150064081Receiver Plate With Multiple Cross-Sections - A multi-well assembly including a filter plate and receiver plate. Each plate includes a plurality of wells, which, when the filter plate is placed in nesting relationship with the receiver plate, each filter plate well has a corresponding receiver plate well into which it extends. The receiver plate wells are of a non-uniform cross-section in order to increase the gap between the outer walls of the filter plate wells and the inner walls of a corresponding receiver plate well when the receiver plate and filter plate are in nesting relationship. The increased gap size reduces wicking and cross-contamination. A multi-section well of maximum cross-section in an upper region and a minimized cross-section in a lower region, with a gradual transition between the regions, is thus provided. The multi-well assembly of the present invention also improves the repeatability of positioning the filter plate and receiver plate in proper nesting relationship and provides stability during handling, mixing and shaking operations.2015-03-05
20150064082Methods and Systems for Using RFID in Biological Field - Biological reagent carrier devices and methods are disclosed, which employ RFID techniques to associate information with biological reagents.2015-03-05
20150064083INJECTOR GRID FOR HIGH AND LOW DUST ENVIRONMENT SELECTIVE CATALYTIC REDUCTION SYSTEMS - A method and an arrangement 2015-03-05
20150064084Method for Treating Discharge Gas - The purpose of the present invention is to provide a method for removing offensive odors from various discharge gases other than exhaust gases of motor vehicle. A method for treating a discharge gas including a discharge-gas treatment device in using an aqueous solution containing strong alkaline electrolyzed water, and directly contacting the discharge gas with the strong alkaline electrolyzed water, having a pH of 9 or higher and an ORP kept at 0 mV or less.2015-03-05
20150064085CO SLIP CATALYST AND METHOD OF USING - A CO slip catalyst, for treating an exhaust gas from a lean burn internal combustion engine, is disclosed. The CO slip catalyst comprises palladium and a ceria-containing material. The invention also includes a method for oxidizing excess CO in an exhaust gas, wherein the excess CO results from the periodic contact of an upstream catalyst under rich exhaust conditions. The method comprises contacting the excess CO in the exhaust gas with a CO slip catalyst at a temperature in the range of 100 to 700° C.2015-03-05
20150064086ELECTRIC REAGENT LAUNCHER FOR REDUCTION OF NITROGEN - A selective catalytic reduction system (SCR) or selective non-catalytic reduction (SNCR) system include a reagent charging apparatus configured to apply one or more electrical charges to a NOx reducing reagent. The electrical charges enhance mixing of the reagent with fluids carrying NOx and/or enhance reactivity of the reagent with NOx.2015-03-05
20150064087REMOVAL OF ATMOSPHERIC POLLUTANTS FROM GAS, RELATED APPARATUS, PROCESSES AND USES THEREOF - Methods related generally to the removal of atmospheric pollutants from the gas phase, are provided, as well as related apparatus, processes and uses thereof. A single-stage air scrubbing apparatus is provided that includes at least one reaction vessel, at least one introduction duct, and a turbulence component, wherein a residence time is sufficient to allow the conversion of at least one atmospheric pollution compound to at least one other compound, molecule or atom. In some embodiments, the at least one atmospheric pollution compound comprises nitrogen oxide, sulfur oxide or a combination thereof. Additionally, methods of removing atmospheric pollution compounds from a waste gas stream are disclosed that include introducing a waste gas stream and at least one additional gas stream, mist stream, liquid stream or combination thereof into a single-stage air scrubbing apparatus at a flow rate sufficient to allow for conversion of the at least one atmospheric pollution compound.2015-03-05
20150064088ZEOLITE BLEND CATALYSTS FOR TREATING EXHAUST GAS - Provided is an improved catalyst for treating exhaust gas, particularly for selectively reducing NO2015-03-05
20150064089FLUIDIZED BED REACTORS INCLUDING CONICAL GAS DISTRIBUTORS AND RELATED METHODS OF FLUORINATION - Embodiments of a fluidized bed fluorination reactor are provided, as are embodiments of a fluidized bed reactor and embodiments of a fluorination method carried-out utilizing a fluidized bed fluorination reactor. In one embodiment, the fluidized bed fluorination reactor includes a source of fluorine gas, a reaction vessel, a windbox fluidly coupled to the source of fluorine gas, and a conical gas distributor fluidly coupled between the reaction vessel and the windbox. The conical gas distributor has a plurality of gas flow openings directing fluorine gas flow from the windbox into the fluorination reaction vessel during the fluorination process.2015-03-05
20150064090SERIES-COUPLED FLUIDIZED BED REACTOR UNITS INCLUDING CYCLONIC PLENUM ASSEMBLIES AND RELATED METHODS OF HYDROFLUORINATION - Embodiments of a series-coupled fluidized bed reactor unit are provided. In one embodiment, the reactor unit includes primary and secondary reactors. The primary reactor includes a reaction vessel, a gas distributor fluidly coupled to the reaction vessel, and a cyclonic plenum assembly. The cyclonic plenum assembly includes a plenum assembly housing, which is fluidly coupled to the gas distributor and which has an annular sidewall; and a gas/solids inlet pipe, which fluidly couples a partially-reacted gas outlet of the secondary reactor to the plenum assembly housing. The gas/solids inlet pipe is tangentially positioned with respect to the annular sidewall of the plenum assembly housing to induce vortex flow within the plenum assembly housing of the partially-reacted gas received from the secondary fluidized bed reactor through the gas/solids inlet pipe to promote the cyclonic separation of entrained solids from the partially-reacted gas prior to entry into the gas distributor.2015-03-05
20150064091METHOD FOR PRODUCING DIFLUOROPHOSPHATE - A process for preparing difluorophosphate comprising reacting difluorophosphoric acid with at least one salt, as a raw material, selected from a halide salt, a carbonate, a phosphate, a hydroxide and an oxide of an alkali metal, an alkaline earth metal or an onium in the difluoraphosphoric acid, then separating a precipitate from the difluorophosphoric acid by solid-liquid separation, the precipitate being precipitated by crystallization operation in the difluorophosphoric acid, and removing the difluorophosphoric acid contained in the precipitate by distillation to obtain difluorophosphate.2015-03-05
20150064092METHODS AND REACTORS FOR PRODUCING SOLID CARBON NANOTUBES, SOLID CARBON CLUSTERS, AND FORESTS - Methods of producing fibrous solid carbon forests include reacting carbon oxides with gaseous reducing agents in the presence of a catalyst having a predetermined grain size to cause growth of fibrous solid carbon forests upon a surface of the metal. The fibrous solid carbon forests are substantially perpendicular to the surface of the metal thus creating the “forests”. A bi-modal forest composition of matter is described in which a primary distribution of fibrous solid carbon comprises the forest and a secondary distribution of fibrous solid carbon is entangled with the primary distribution. A reactor includes a catalyst, a means for facilitating the reduction of a carbon oxide to form solid carbon forests on a surface of the catalyst, and a means for removing the solid carbon forest from the surface of the metal catalyst.2015-03-05
20150064093MESOPOROUS SILICA AND ORGANOSILICA MATERIALS AND PROCESS FOR THEIR PREPARATION - In this invention, we disclose a method as well as silica and/or organosilica mesoporous materials obtained by templating using nanocrystalline cellulose and removal of the latter using acidic conditions. The resultant mesoporous silica materials are characterized by having high surface area with tunable iridescence resulting from the long-range chiral nematic organization. This invention is an improvement over the formation of composite materials formed with nanocrystalline cellulose (NCC) and silica, where the calcination of the materials led to removal of the cellulose and formation of a mesoporous silica material. Characteristically, the removal of the NCC template using acidic conditions differentiates the silica materials thus obtained in two ways: (1) It does not lead to as significant contraction of the materials as from calcination thereby giving access to materials with larger mesopores; and (2) it allows the formation of mesoporous chiral nematic compositions that include heat-sensitive components. This approach may be used to prepare the first example of a mesoporous organosilica material with a chiral nematic pore structure. Examples of possible applications of this material include optical filters, adsorbents, chiral stationary phases for chromatography, sensors, composite materials, membranes, and templates for creating other chiral materials.2015-03-05
20150064094METHOD OF PREPARING TITANIUM CARBIDE POWDER - Disclosed herein is a method for preparing titanium carbide powder. More specifically, the method comprises the steps of: mixing titanium dioxide (TiO2015-03-05
20150064095Method of Producing a Molecular Structure - A method of producing a molecular structure comprises determining a desired shape of the molecular structure; providing a multi-layer structure, the multilayer structure having at least first and second adjacent generally planar molecular layers, the first and second generally planar molecular layers each consisting of an array of covalently bonded atoms; arranging the multi-layer structure in a desired orientation relative to a cutter; using the cutter to break bonds within the first generally planar molecular layer to produce a first edge of a desired configuration corresponding to the desired shape of the molecular structure; and using the cutter to break bonds within the second generally planar molecular layer to produce a second edge of a desired configuration corresponding to the desired shape of the molecular structure; and allowing the first edge of the first generally planar molecular layer and the second edge of the second generally planar molecular layer to relax so that the first edge of the first generally planar molecular layer and the second edge of the second generally planar molecular layer covalently bond to one another.2015-03-05
20150064096METHODS AND SYSTEMS FOR THERMAL ENERGY RECOVERY FROM PRODUCTION OF SOLID CARBON MATERIALS BY REDUCING CARBON OXIDES - A method of thermal energy recovery from production of at least one solid carbon material comprises reacting at least one carbon oxide material and at least one gaseous reducing material at a temperature of greater than or equal to about 2015-03-05
20150064097CARBON NANOTUBES HAVING A BIMODAL SIZE DISTRIBUTION - A composition comprising a mixture of carbon nanotubes having a bi-modal size distribution are produced by reducing carbon oxides with a reducing agent in the presence of a catalyst. The resulting mixture of nanotubes include a primary population of multiwall carbon nanotubes having characteristic diameters greater than 40 nanometers, and a secondary population of what are apparently single wall nanotubes with characteristic diameters of less than 30 nanometers. The resulting mixture may also contain one or more other allotropes and morphologies of carbon in various proportions. The mixture of carbon nanotubes has specific apparently uncommon properties, including unusual resistivity and density2015-03-05
20150064098PROCESS FOR PRODUCING TWO-DIMENSIONAL NANOMATERIALS - The present invention provides a process for producing a two-dimensional nanomaterial by chemical vapour deposition (CVD), the process comprising contacting a substrate in a reaction chamber with a first flow which contains hydrogen and a second flow which contains a precursor for said material, wherein the contacting takes place under conditions such that the precursor reacts in the chamber to form said material on a surface of the substrate, wherein the ratio of the flow rate of the first flow to the flow rate of the second flow is at least 5:1. Two-dimensional nanomaterials obtainable by said process are also provided, as well as devices comprising said nanomaterials.2015-03-05
20150064099Method For Carbon Black Production Using Preheated Feedstock And Apparatus For Same - Methods for production of carbon black using high temperature feedstock at temperatures exceeding about 2015-03-05
20150064100Purification of Titanium Tetrachloride - Disclosed is a process/system for the removal of metal chloride impurities from a titanium tetrachloride stream. The metal chloride impurities are removed through contact of the titanium tetrachloride stream with an alumino-silicate material, which can be selected based on certain properties of the alumino-silicate and based on the geometries of the impurity(ies) and the alumino-silicate.2015-03-05
20150064101DEVICE AND METHOD FOR MAKING A DILUTE AQUEOUS SOLUTION OF PEROXOMONOSULPHURIC ACID - A device, comprising a conduit for an aqueous stream, a mixing tube located inside the conduit, having a static mixer inside the mixing tube, an outlet open to the conduit and an inlet, a sulphuric acid supply tube connected to the inlet of the mixing tube and a hydrogen peroxide supply tube, arranged inside the sulphuric acid supply tube and having an outlet for hydrogen peroxide at the inlet of said mixing tube, and a method, where an aqueous stream is passed through the conduit of the device, 85 to 98% by weight sulphuric acid is introduced to the sulphuric acid supply tube of the device and 50 to 80% by weight aqueous hydrogen peroxide solution is introduced to the hydrogen peroxide supply tube of the device, provide a dilute aqueous solution of peroxomonosulphuric acid without a risk of exposing operating personnel to concentrated peroxomonosulphuric acid.2015-03-05
20150064102Hydrogen Oxidation Catalyst, Use Thereof, And Method For Hydrogen Recombination - A hydrogen oxidation catalyst is provided, comprising a zeolite that contains at least one catalytically active noble metal or a compound thereof, wherein said zeolite is a hydrophobic zeolite. A use of the catalyst and a method for hydrogen recombination in nuclear power plants, reprocessing plants or fuel element repositories is also specified.2015-03-05
20150064103METHODS OF MAKING FERRITE NANOCRYSTALS - Methods of making iron-based ferrite nanocrystals are provided. In such methods the ferrite may include iron oxides and iron/cobalt or iron/manganese mixed salts. The method may include thermal decomposition of one or more precursors of the ferrite, consisting of an organic salt of the metal or metals constituting the ferrite of interest, comprising the operation of heating a solution comprising said precursor(s) in the presence of a surfactant and of a non-aqueous organic solvent comprising an ether, at temperature sufficient to cause thermal decomposition of said precursor, wherein the solvent may further comprise a saturated or unsaturated, linear or branched aliphatic hydrocarbon, liquid at temperatures above 45° C. and having a boiling point above the boiling point of the ethereal solvent.2015-03-05
20150064104HYDROGEN GENERATOR WITH SEQUENTIAL FUEL INITIATION - Disclosed is a hydrogen generator that produces hydrogen by thermal decomposition. An electric circuit including a plurality of parallel branches, each including at least one electric heating element, is arranged in a sequence. The circuit also includes a normally open switch between adjacent branches and a normally closed switch in each branch but the last to provide current to the heating elements in the sequence of the parallel branches. Each heating element provides heat to thermally decompose a portion of a reactant, open the normally closed switch in the same branch, and close the normally open switch following that branch, energizing and deenergizing the heating elements in sequence. Each of the normally open switches includes a switch material with a resistivity that permanently decreases to close the switch in response to heating, and each of the normally closed switches opens in response to heating.2015-03-05
20150064105Tethered Transition Metals Promoted Photocatalytic System for Efficient Hydrogen Evolutions - The present invention is directed, at least in part, to a process for improving the efficiency of a photocatalyst (a semiconductor photocatalyst) by tethering (depositing) a metal (e.g., metal ions of a late transition metal, such as nickel) to the semiconductor (photocatalyst) surface through the use of an organic ligand. More specifically, 1,2-ethanedithiol (EDT) functions as an excellent molecular linker (organic ligand) to attach a transition metal complex (e.g., nickel (Ni2015-03-05
20150064106Biodegradable Polyphosphazenes Containing Pyrrolidone Side Groups - Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed.2015-03-05
20150064107IMAGING AGENT - The invention relates to imaging agents, and in particular to multi-modal nanoparticle (NPIA) imaging agents offering magnetic, radionuclide and fluorescent imaging capabilities to exploit the complementary advantages of magnetic resonance imaging (MRI), positron emission tomography (PET), single-photon emission computed tomography (SPECT) and optical imaging (OI). The invention extends to these new types of agents per se, and to uses of such agents in various biomedical applications, such as in therapy and in diagnosis.2015-03-05
20150064108METHOD OF PREPARING RADIOISOTOPE HYBRID NANOCOMPOSITE PARTICLES USING SOL-GEL REACTION AND RADIOISOTOPE HYBRID NANOCOMPOSITE PARTICLES PREPARED USING THE SAME - A method of preparing radioisotope hybrid nanocomposite particles using a sol-gel reaction, and radioisotope hybrid nanocomposite particles prepared using the same are provided. The method includes preparing a complex precursor using a metal ion and an unshared electron pair reactive compound, growing hybrid nanocomposite particles based on the complex precursor by means of a sol-gel reaction, calcining the nanocomposite particles in the air to remove organic matters present in the nanocomposite particles, and irradiating the nanocomposite particles with neutrons to prepare radioisotope hybrid nanocomposite particles. The radioisotope nanocomposite particles prepared using the method can be used as diagnostic and therapeutic particles in the fields of oil refining, chemistry, cement, agriculture, water resources, environment, ocean, and medicine, and can also be used as a radioisotope tracer for evaluating the risk of nanomaterials.2015-03-05
20150064109Quantified differentiation and identification of changes in tissue by enhancing differences in blood flow and metabolic activity - The invention provides a novel quantitative method for differentiating and identification of changes in tissue by enhancing differences in blood flow prior to administering a radiopharmaceutical, which differentially accumulates in tissue based upon differences in blood flow and metabolic activity. In one embodiment the enhancing agent is 0.852 mg per kilogram body weight dipyridamole and the radiopharmaceutical is Technetium-99m hexakis 2-methoxyisobutylisonitrile (sestamibi) and the tissue differentiation is calcification, normal, inflammatory, precancerous and cancerous breast tissue. The present invention allows differentiation between regions of calcification, nonliving or metabolically inactive tissue, normal tissue, pre-cancerous and cancerous tissue. The present invention allows for quantification of changes in tissue to determine the effect of treatment upon tissue.2015-03-05
20150064110CROSSLINKED POLYSACCHARIDE BEADS COMPRISING AN IMAGING AGENT - The present invention relates to a method for preparing beads comprising imaging agent. The present invention further provides beads highly useful for medical imaging.2015-03-05
20150064111NOVEL TARGETING AGENTS FOR DIAGNOSTIC AND THERAPEUTIC INDICATIONS - The invention relates to compounds and use thereof in the diagnosis and/or in treatment of medical disorders. In some embodiments, the compounds may be used for detecting a cancer. The compound may include a di-acid moiety. In some embodiments the di-acid moiety comprises a di-carboxylic acid and in some embodiments the di-acid moiety comprises a di-tetrazole.2015-03-05
20150064112USE OF T1R3 VENUS FLYTRAP REGION POLYPEPTIDE TO SCREEN FOR TASTE MODUALTORS - The invention relates to compounds that specifically bind a T1R1/T1R3 or T1R2/T1R3 receptor or fragments or sub-units thereof. The present invention also relates to the use of hetero-oligomeric and chimeric taste receptors comprising T1R1/T1R3 and T1R2/T1R3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli. Further, the invention relates to the constitutive of cell lines that stably or transiently co-express a combination of T1R1 and T1R3; or T1R2 and T1R3; under constitutive or inducible conditions. The use of these cells lines in cell-based assays to identify umami and sweet taste modulatory compounds is also provided, particularly high throughput screening assays that detect receptor activity by use of fluorometric imaging.2015-03-05
20150064113CONTRAST AGENTS BASED ON LONG-LIVED NUCLEAR SINGLET STATES AND RELATED METHODS - Methods are described for preparing magnetic resonance imaging (MRI) and/or magnetic resonance spectroscopy contrast agents where the contrast agents are prepared from precursor molecules having at least four non-zero-spin nuclei that form two pairs of chemically equivalent or effectively equivalent nuclei, e.g., diphenylacetylene or diethyl oxalate. The precursor molecule is hyperpolarized and a sequence of one or more radiofrequency pulses is applied to transfer spin state population between the first and second pair of nuclei, thereby providing a non-equilibrium single state nuclear spin population. To detect the contrast agent, another sequence of one or more radiofrequency pulses is applied to transfer singlet order to polarization. No transformation of the molecular structure of the contrast agent is necessary for detection. Also described are methods of imaging targets using the contrast agents.2015-03-05
20150064114LIPOSOME INCLUDING HYDROPHOBIC MATERIAL AND IMAGING AGENT AND USE OF THE LIPOSOME - A liposome comprising a lipid bilayer, a hydrophobic active ingredient, and an imaging agent, a pharmaceutical composition including the liposome, and a method of delivering an active ingredient to a target site in the body of a subject using the liposome.2015-03-05
20150064115NEUROPHILIC NANOPARTICLES - Novel liposomal nanoparticle that has been engineered to be particularly useful for the delivery of compounds to cells found in the peripheral nervous system, and to endothelial cells that form the blood brain barrier. These nanoparticles are intended to be useful for the delivery of compounds suitable for therapeutic purposes and imaging contrast agents that may not otherwise gain access to neuronal axons, or glial cells regions of the brain. Particularly advantageous for the purpose of targeting neural cells, endothelial cells of the blood vessels and epithelial cells of the choroid plexus that serve the brain is the inclusion, in the nanoparticles of cholesterol that surprisingly increases the affinity of the nanoparticles for such as Schwann cells, glial cells, and the like. Image contrast agents, such as those suitable for use in MRI techniques may also be delivered to neural cells, including of the peripheral nervous system. These advantageous liposomal nanoparticles at least comprise a phospholipid, a non-ionic surfactant, and cholesterol (or a derivative thereof).2015-03-05
20150064116MULTILAYERED MAGNETIC MICELLE COMPOSITIONS AND METHODS FOR THEIR USE - Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second coating comprising a polynucleotide. Also provided are methods of using the compositions for transfection and/or transformation of a cell with the polynucleotide. Further provided are methods of detecting transfection of a cell with the polynucleotide.2015-03-05
20150064117NOVEL POLYMORPHS OF REBAUDIOSIDE C AND METHODS FOR MAKING AND USING THE SAME - Embodiments of this invention encompass a method for producing and purifying rebaudioside C. In particular, this invention relates to a method for purifying rebaudioside C compositions to obtain a substantially pure rebaudioside C product using one or more crystallization steps. Resulting polymorphic forms of rebaudioside C, substantially pure rebaudioside C compositions and their uses are disclosed.2015-03-05
20150064118LIPID DEPOT FORMULATIONS - The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of:2015-03-05
20150064119COSMETIC ADDITIVES CONTAINING ALKALI PHOSPHATES - The invention relates to a cosmetic formulation comprising an additive agent. The additive agent having a water soluble linear alkali polyphosphate with a chain length of at least 4 to 50. The alkali polyphosphate exhibits complexing, dispersing, and antimicrobial effects. The alkali polyphosphate has a pH in the range of 6.5 to 8.5 (in aqueous solutions).2015-03-05
20150064120USE OF PORPHYRIN-TYPE CATALYTIC OXIDATION COMPOUNDS AS AN ANTI-DANDRUFF AGENT - The present invention relates to the cosmetic use, as an antidandruff agent, of catalytic oxidation compounds chosen from porphyrins, or of a cosmetic composition comprising the same.2015-03-05
20150064121COSMETIC COMPOSITION COMPRISING A SYNERGISTIC TRF2 PROTEIN ACTIVATION SYSTEM CONSISTING OF A COMBINATION OF A PEPTIDIC SOYBEAN AND YEAST EXTRACT AND THE USES THEREOF - A cosmetic composition having a synergistic TRF2 protein activation system consisting essentially of a combination of a peptidic soybean and yeast extract in a physiologically acceptable medium is disclosed and protecting or treating damage to the DNA of skin cells associated with aging by applying the cosmetic composition thereto, typically topically. The peptidic soybean and yeast extract is obtained by hydrolyzing at least 80% of soybeans by weight of the total weight of raw materials and at most 20% of yeast by weight of the total weight of raw materials.2015-03-05
20150064122SKIN AND/OR HAIR WHITENING MIXTURE - Suggested is a skin or hair whitening mixture, comprising 2015-03-05
20150064123HIGH ENERGY VISIBLE LIGHT FILTER SYSTEMS WITH YELLOWNESS INDEX VALUES - The present invention relates to ophthalmic and non-ophthalmic systems with blue light filtering and Yellowness Index ranges. UV and IR filtering are also included. Industrial applications are also outlined in the invention.2015-03-05
20150064124PERSONAL CARE FORMULATIONS CONTAINING ALKYL KETAL ESTERS AND METHODS OF MANUFACTURE - Personal care formulations containing alkyl ketal esters having the structure2015-03-05
20150064125Topical skin care formulations - A white, color-stable, stain-free emulsion formulation containing vanillin for sunless tanning. The amount of vanillin can be adjusted, from about 1% up to about 45%, to provide light or dark tanning of the skin. Lime oil and lime juice form a preferred white emulsion foundation.2015-03-05
20150064126USE OF CHITOSANS FOR THE TREATMENT OF NAIL INFLAMMATORY DISEASES - Chitosan-based nail formulations are useful to treat nail inflammatory diseases such as psoriasis, atopic dermatitis and lichen planus. The chitosan is normally in the form of an amino-polysaccharide derivative, preferably water soluble, such as hydroxypropyl chitosan. The formulation may be a nail lacquer, a spray, a cream, an ointment, a gel, a lotion or a foam and may comprise chitosan, a chitosan derivative or a salt thereof in an amount from 0.1 to 25 wt. % with respect to the total weight of the formulation.2015-03-05
201500641274-OXO-2-PENTENOIC ACID AND SKIN PIGMENTATION - The present invention relates generally to the field of enhancing skin appearance. One aspect of the invention aims to provide a composition comprising 4-oxo-2-pentenoic acid for use in the reduction or prevention of regions of the skin with darker pigmentation. The present invention also relates to cosmetic use of a composition comprising 4-oxo-2-pentenoic acid for the reduction or prevention of regions of the skin with darker pigmentation.2015-03-05
20150064128CATIONIZED GLYCEROLATED CELLULOSE - A cationized glycerolated cellulose which, when blended in a hair cosmetic, is able to impart excellent smoothness and its long-lasting feeling at the time of rinsing and to impart a moist feeling and softness to the hair after drying and, when blended in a skin cleanser, is able to impart an excellent moisturizing feeling after drying; a surfactant composition containing the same; and a hair cosmetic composition and a skin cleanser composition each containing the surfactant composition, are provided. [1] A cationized glycerolated cellulose having a specified structure, which has a main chain derived from an anhydroglucose, wherein a degree of substitution of a cationized alkylene oxy group per the anhydroglucose unit is from 0.01 to 0.18, and a degree of substitution of a glycerol group per the anhydroglucose unit is from 0.5. to 5.0; [2] a surfactant composition containing the above-described cationized glycerolated cellulose, a surfactant, and water; [3] a use of the above-described surfactant composition as a hair cosmetic composition and a skin cleanser composition; and [4] a hair cosmetic composition and a skin cleanser composition each containing the above-described cationized glycerolated cellulose, a surfactant, and water, are disclosed.2015-03-05
20150064129WOUND HEALING COMPOSITION - The invention discloses a composition comprising hyaluronic acid with a high molecular weight and povidone-iodine in low amount that has advantageous efficacy in enhancing wound healing and maintains high stability. Also disclosed is a method of using the composition of the invention in healing wounds.2015-03-05
20150064130PROTEIN-POLYMER-DRUG CONJUGATES - Auristatin compounds and conjugates thereof are provided herein. The conjugate comprises a protein based recognition-molecule (PBRM) and a polymeric carrier substituted with one or more -L2015-03-05
20150064131PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE - A pharmaceutical composition comprising a polymeric binder including a high molecular weight synthetic polymer having a backbone constituted of non hydrolysable covalent bonds, said polymer being able to form electrostatic bonds at a pH lower than the isoelectric point of gluten and peptides derived from the degradation of gluten, and being able to bind to gluten or peptides derived from the degradation of gluten in the gastrointestinal tract, and a pharmaceutically acceptable carrier. Methods of using the polymeric binder for binding gluten or a peptide derived from the degradation of gluten, for decreasing the degradation of gluten into toxic peptides or for decreasing interaction of gluten or peptides derived from the degradation of gluten with the gastrointestinal mucosa.2015-03-05
20150064132Treatment Methods for Rheumatoid Arthritis - The present invention provides methods for selecting treatment methods for rheumatoid arthritis based on an objective selection process (algorithm). The present invention also provides methods for treating rheumatoid arthritis with treatment methods selected based on the algorithm disclosed herein. The methods of the present invention provide a more effective means for treating patients with rheumatoid arthritis.2015-03-05
20150064133BIOACTIVE COMPOSITIONS DERIVABLE FROM PLATELET CONCENTRATES, AND METHODS FOR PREPARING AND USING SAME - The present disclosure provides a composition comprising a bioactive fraction derived from a platelet concentrate, methods of making the bioactive fraction, and culture medium supplemented with the bioactive fraction. Preferred bioactive fractions have relatively low fibrinogen concentrations while retaining native growth factors in beneficial amounts and ratios.2015-03-05
20150064134COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING DISEASES, CONDITIONS, OR PROCESSES CHARACTERIZED BY ABERRANT FIBROBLAST PROLIFERATION AND EXTRACELLULAR MATRIX DEPOSITION - The described invention provides compositions and methods for treating asthma, a disease, condition or pathologic process whose progression is characterized by one or more of aberrant fibroblast proliferation and extracellular matrix deposition producing constriction in an airway, airway remodeling, and airway obstruction in lung tissue. The method includes administering a pharmaceutical composition comprising a therapeutic amount of a polypeptide having the amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or functional equivalent thereof, and a pharmaceutically acceptable carrier, wherein the therapeutic amount of the polypeptide is effective to reduce the constriction of small airway dimensions and airway obstruction, treat airway remodeling, or a combination thereof.2015-03-05
20150064135AGENT FOR THE TREATMENT OF VIRAL HEPATITIS C - The invention relates to medicine and comprises an agent for the treatment of a viral hepatitis C, which is glutaryl histamine or a pharmaceutically acceptable salt thereof. This agent can also be administered in combination with a pegylated interferon and ribavirin. The invention further relates to a pharmaceutical composition for the treatment of a viral hepatitis C. This invention solves the problem of providing a novel agent, which is effective in the treatment of a viral hepatitis C and makes it possible to produce a sustained virologic response.2015-03-05
20150064136PREDICTORS OF PATIENT RESPONSE TO INTERFERON-A THERAPY - The present invention relates to methods and materials for more effectively treating patients with interferon. It is based on the discovery that clinical response to interferon (IFN) therapy is mediated in part by inhibition of activation of MDSC and such inhibition can be observed after a test dose of interferon; a significant decrease of reactive oxygen species (ROS) production by MDSC (as a measure of their activation) after IFN therapy is predictive of overall response to immunotherapy in cancer patients.2015-03-05
20150064137USE OF ENGINEERED VIRUSES TO SPECIFICALLY KILL SENESCENT CELLS - Polypeptides, viruses, methods and compositions provided herein are useful for the selective elimination of senescent cells. Method aspects include methods for inducing apoptosis in a senescent cell comprising administering to the cell a polynucleotide, virus, host cell, or pharmaceutical composition described herein. Other methods include expressing a pro-apoptotic gene in a senescent cell comprising administering to the cell the polynucleotide, virus, or pharmaceutical composition as described herein.2015-03-05
20150064138TUNING MICROBIAL POPULATIONS WITH PROGRAMMABLE NUCLEASES - Various aspects and embodiments of the invention are directed to methods and compositions for reversing antibiotic resistance or virulence in and/or destroying pathogenic microbial cells such as, for example, pathogenic bacterial cells. The methods include exposing microbial cells to a delivery vehicle with at least one nucleic acid encoding an engineered autonomously distributed circuit that contains a programmable nuclease targeted to one or multiple genes of interest.2015-03-05
20150064139CELL POTENCY ASSAY FOR THERAPEUTIC POTENTIAL - The invention provides cell potency assays for measuring, determining, identifying, confirming, or validating the therapeutic potential of a cell population. Cell potency assays may be performed with various types of cells, including stem or progenitor cells, such as, for example, hematopoietic stem or progenitor cells. Cell potency assays may also be performed on stem or progenitor cells that have been treated with one or more agents to enhance therapeutic potential. Hematopoietic cells having therapeutic potential are useful in downstream clinical applications for increasing engraftment, reconstitution, homing, and proliferation in vivo.2015-03-05
20150064140METHODS AND USES OF BIOLOGICAL TISSUES FOR VARIOUS STENT AND OTHER MEDICAL APPLICATIONS - Methods and uses of biological tissues for various stent and other medical applications. In an exemplary embodiment of a method of processing a tissue of the present disclosure, the method comprises the steps of acquiring a mammalian tissue comprising at least a portion of a pulmonary region tissue, selecting a sample of pulmonary region tissue from the at least a portion of a pulmonary region tissue, and fixing the sample of pulmonary region tissue using a fixative, resulting in a fixed sample. In at least one embodiment, the step of selecting a sample of pulmonary region tissue comprises selecting a sample of pulmonary ligament tissue from the mammalian tissue.2015-03-05
20150064141REGENERATIVE SERA CELLS AND MESENCHYMAL STEM CELLS - Disclosed herein are three types of skin-derived cells. One type of the cells is mesenchymal stem cells characterized by expression of the cell surface biomarker cluster of differentiation (CD) 146, the second type expresses CD271. The third type of cells is regeneration-associated cells characterized by expression of the cell surface biomarkers stage-specific embryonic antigen 3 (SSEA3) and CD 105 (clone 35). Also disclosed are methods of isolating, purifying, culturing, storing, and using these cells.2015-03-05
20150064142ELASTIC SCAFFOLDS FOR TISSUE GROWTH - According to some aspects, tissue scaffolds are provided that comprise one or more types of nanofibers. In some embodiments, one or more design features are incorporated into a tissue scaffold (e.g., an electrospun tissue scaffold) to control the elasticity of the scaffold in at least one direction, making the scaffold suitable for withstanding mechanical forces when implanted in the body of a subject2015-03-05
20150064143IONICALLY CROSS-LINKABLE ALGINATE-GRAFTED HYALURONATE COMPOUND - The present invention provides an ionically cross-linkable alginate-grafted hyaluronate compound containing alginate and hyaluronate, the alginate and the hyaluronate forming a covalent linkage. The use of the compound can easily provide a cross-linked hyaluronate by adding a divalent cation without using a chemical cross-linking agent. The present invention also provides a method for cell transplantation that includes preparing a composition comprising the compound of claim 2015-03-05
20150064144Non-Invasive In Vivo Imaging and Methods for Treating Type I Diabetes - The present invention provides novel drug discovery platforms and methods for treating type I diabetes.2015-03-05
20150064145BONE MARROW-DERIVED MESENCHYMAL STEM CELLS AS A SOURCE OF NEURAL PROGENITORS - Methods are provided for treating and/or reducing the severity of multiple sclerosis in a human, by administering autologous mesenchymal stem cell-derived neural precursors. Also described is an in vitro method for differentiating mesenchymal stem-cell derived neural precursor oligodengroglial and neuronal cell types.2015-03-05
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