08th week of 2016 patent applcation highlights part 35 |
Patent application number | Title | Published |
20160054249 | OXIDATION CATALYST DETECTOR FOR AIRCRAFT COMPONENTS - The exposure of an aircraft component to an oxidation catalyst, such as a deicing solution, may be detected with the aid of an electrical conductivity sensor. In some examples, a system includes an aircraft component, an electrical conductivity sensor mechanically connected to the aircraft component and configured to generate an output, and a processor configured to detect an oxidation catalyst exposure event based on the output generated by the electrical conductivity sensor. The electrical conductivity sensor may be configured and positioned to generate a signal indicative of electrical conductivity of a substance to which the aircraft component is exposed. The processor may be configured to detect an oxidation catalyst exposure event by at least determining whether the electrical conductivity indicated by the signal is greater than or equal to a predetermined conductivity threshold value. | 2016-02-25 |
20160054250 | ROUTE EXAMINING SYSTEM AND METHOD - A system may include a coded test signal transmission system configured to transmit a unique coded test signal along a route, and a coded test signal receiving system configured to receive the unique coded test signal along the route. The unique coded test signal received by the coded test signal receiving system is used to determine one or more characteristics of the route. | 2016-02-25 |
20160054251 | DEVICE FOR DETECTING CONTACT OF AN ELECTRICAL CONDUCTOR BY A TOOL - The invention relates to a device for detecting contact of a tool ( | 2016-02-25 |
20160054252 | Electrochemical Biosensor - Provided is a biosensor having i) sufficient sensitivity allowing quantitative detection of a low concentration of an analyte; and ii) excellent selectivity allowing selective distinction of the presence of an analyte. | 2016-02-25 |
20160054253 | Carbon-Sulfur Based Core-Shell Materials Compositions, Methods, and Applications - A materials composition and a method for preparing the materials composition provide: (1) a core material comprising a reactive carbon material-sulfur material composite; surrounded by and chemically coupled with (2) a shell material comprising a reactive sheath material. The material composition is useful within electrodes within electrical components including but not limited to electrochemical gas cells, supercapacitors and batteries where enhanced cycling may be realized. | 2016-02-25 |
20160054254 | Electron Mediator and Electrochemical Biosensor Employing the Same - Provided is an electron mediator system, which may include a first transition metal complex and a second transition metal complex, wherein a working potential of the electron mediator system may be substantially the same as a molar average of a working potential of the first transition metal complex and a working potential of the second transition metal complex. | 2016-02-25 |
20160054255 | CONCENTRATION DETERMINATION IN A DIFFUSION BARRIER LAYER - The present invention relates to improved electrochemical biosensor strips and methods for determining the concentration of an analyte in a sample. By selectively measuring a measurable species residing in a diffusion barrier layer, to the substantial exclusion of the measurable species residing exterior to the diffusion barrier layer, measurement errors introduced by sample constituents, such as red blood cells, and manufacturing variances may be reduced. | 2016-02-25 |
20160054256 | GAS SENSOR ELEMENT AND GAS SENSOR - A gas sensor element includes a laminate formed of a detecting element section and a heater section, and a porous protection layer covering a forward end portion of the laminate. The detecting element section has one or more cells having a solid electrolyte body and a pair of electrodes. The heater section has a heater. Side surfaces of the solid electrolyte bodies in parallel with the direction of lamination are covered with dense insulating members. The cell-to-be-controlled is temperature controlled by the heater to 600° C. to 830° C. The porous protection layer is formed on the laminate from a forward end portion to a region which has a temperature of 500° C. or higher when the temperature control is performed, and the porous protection layer is not formed in a region which has a temperature of 300° C. or lower when the temperature control is performed. | 2016-02-25 |
20160054257 | Electrolyte Concentration Measuring Apparatus and Measuring Method Using Same - An electrolyte concentration measuring apparatus is provided with: a plurality of ion selective electrodes and one reference electrode; a sample introduction unit that introduces a sample solution to the plurality of ion selective electrodes and the reference electrode; a potential measuring unit that measures a voltage between the plurality of ion selective electrodes and the reference electrode; and a resistance measuring unit that measures a direct-current resistance of the plurality of ion selective electrodes. | 2016-02-25 |
20160054258 | NANOSTRUCTURED SENSOR ARCHITECTURE AND METHOD FOR ENHANCED CHEMICAL DETECTION - Apparatus for detecting and identifying a chemical species in an environment, the apparatus comprising: a plurality of carbon nanotubes arranged to form a network, the network comprising a plurality of inter-carbon nanotube junctions; a plurality of electrical contacts, each of the plurality of electrical contacts being connected to the network such that the anisotropic electrical characteristics of the network can be measured dynamically while the network is exposed to the environment; wherein the network possesses electrical anisotrophy such that the ratio of the number of inter-carbon nanotube junctions which must be traversed by current per length of the plurality of carbon nanotubes differs for different directions within the network along the path from one of the plurality of electrical contacts to another of the plurality of electrical contacts, and further wherein the electrical anisotrophy of the network changes when a chemical species is present in the environment. | 2016-02-25 |
20160054259 | ANALYZER FOR MONITORING SALT CONTENT IN HIGH RESISTIVITY FLUIDS - An electrochemical polymerization based salt content analyzer configured to determine salt composition in a direct, fast, and serial manner. The salt content analyzer includes three electrodes: a working electrode, a counter electrode and a reference electrode. In operation, the current passing through the electrodes as a sweeping voltage is applied may be analyzed to determine the salt content of the analyte. The working electrode includes an access control mechanism to only expose a fraction of the working length of the working electrode to the outside environment at any given time. The access control mechanism is advanced between tests to expose a fresh portion of the working electrode. Thus, testing may be performed in a serial manner. | 2016-02-25 |
20160054260 | METHOD AND APPARATUS ANALYZING A TARGET MATERIAL - Aspects of the subject disclosure may include, for example, an apparatus including a material having one or more atomic layers with two or less degrees of freedom for motion of charges in the material, and a gate coupled to the material for controlling charge concentration of the material. The material can have constricted sides, a first through-hole, and a first port and a second port for conduction of charges in the material. The gate can have a second through-hole that is at least partially aligned with the first through-hole. A first voltage potential can be applied to the first port and the second port, along with a second voltage potential applied to the gate which adjusts the charge concentration of the material. A sensor can be used to measure a change in electrical properties of the material caused by a target material traversing the first through-hole of the material. Additional embodiments are disclosed. | 2016-02-25 |
20160054261 | USE OF MICROFLUIDIC SYSTEMS IN THE ELECTROCHEMICAL DETECTION OF TARGET ANALYTES - The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes. | 2016-02-25 |
20160054262 | SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR PROVIDING GENERALIZED LOCAL MAXWELL TOMOGRAPHY FOR MAPPING OF ELECTRICAL PROPERTY GRADIENTS AND TENSORS - Exemplary system, method, and computer-accessible medium can be provided for determining at least one property (e.g., an electrical property or a cross-section property) of at least one target. For example, it is possible to determine electromagnetic-field-related quantities associated with signals provided from the target(s). The electromagnetic-field-related quantities can be provided to procedures to relate the electromagnetic-field-related quantities to a plurality of unknown electrical property values and residual field-related unknown values of the target(s). The property(ies) of the target(s) can be determined by determining the plurality of unknown electrical property values and residual field-related unknown values of the target(s). | 2016-02-25 |
20160054263 | ION MODIFICATION - An ion mobility spectrometry method comprising determining whether a sample comprises ions having a first characteristic, and in the event that it is determined that the sample comprises ions having the first characteristic, applying thermal energy together with a radio frequency, RF, electric field to parent ions so as to obtain daughter ions having a second characteristic for inferring at least one identity for the parent ions based on the first characteristic and the second characteristic. | 2016-02-25 |
20160054264 | A Method of Screening Samples - A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest. | 2016-02-25 |
20160054265 | ENVIRONMENT DETECTING APPARATUS EMPLOYING AN ASYMMETRIC WAVEFORM PULSE GENERATOR - An environment detecting apparatus employing an asymmetric waveform pulse generator is disclosed. The asymmetric waveform pulse generator comprises a metal oxide semiconductor field effect transistor (MOSFET) bridge circuit that comprises a plurality of MOSFETs for inverting high voltage DC voltage to asymmetric waveform pulses, a pulse-width modulating (PWM) circuit for generating PWM signals, and a plurality of isolation driving circuits corresponding to the plurality of MOSFETs, for controlling switching on/off of the plurality of MOSFETs in the MOSFET bridge circuit based on the PWM signals generated by the PWM circuit. Wherein each of the isolation driving circuits comprises an isolation transformer for isolating the MOSFET bridge circuit from the PWM circuit. | 2016-02-25 |
20160054266 | ULTRASONIC FLAW DETECTION METHOD AND ULTRASONIC FLAW DETECTION APPARATUS - An ultrasonic flaw detection method includes a condition setting step of setting a boundary echo detection threshold and a gate end point relative position, according to a type of a test object, a flaw detection signal obtaining step of obtaining a flaw detection signal by converting ultrasonic waves received from the test object to an electric signal, a boundary echo detection step of detecting a boundary echo detection time of the flaw detection signal by using the boundary echo detection threshold, a flaw echo detection gate setting step of setting an end point of a flaw echo detection gate by subtracting the gate end point relative position from the boundary echo detection time, and a flaw echo detection step of detecting a flaw echo by using the flaw detection signal within the flaw echo detection gate. | 2016-02-25 |
20160054267 | APPARATUS FOR ANALYZING ACTIVE MATERIAL OF SECONDARY BATTERY AND METHOD OF ANALYZING ACTIVE MATERIAL USING THE SAME - An apparatus for analyzing an active material of a secondary battery may include: a first electrode; a piezoelectric layer on the first electrode; a second electrode on the piezoelectric layer, configured to provide a voltage having a polarity opposite to a polarity of the first electrode; and/or an insulating layer on the second electrode and including a through hole exposing a portion of the second electrode. A method of analyzing an active material of a secondary battery may include: disposing an active material in a through hole of a bulk acoustic resonator, in which a first electrode, a piezoelectric layer, a second electrode, and an insulating layer are stacked; measuring a resonance frequency of the resonator by applying an electric signal to the first and second electrodes of the resonator; and/or measuring a weight of the active material in the through hole, based on the measured resonance frequency. | 2016-02-25 |
20160054268 | PASSIVE BUBBLE MINIMIZATION IN ULTRASONIC TESTING - To avoid the detrimental effects of bubbles in the carrying out of immersion ultrasonic testing, various surfaces may be coated with a coating that includes appropriately selected compounds. Such compounds may include those compounds that cause higher local surface tension and those compounds that are hydrophilic. Furthermore, various surfaces involved in the testing may be coated in a manner that minimizes cavities and crevices to which air bubbles can adhere. | 2016-02-25 |
20160054269 | Systems for Characterizing Resonance Behavior of Magnetostrictive Resonators - Illustrative embodiments of systems for characterizing resonance behavior of magnetostrictive resonators are disclosed. In one illustrative embodiment, an apparatus may comprise a first channel including one or more driving coils and one or more magnetostrictive resonators, the first channel having a first impedance; a second channel having a second impedance, the second impedance differing from the first impedance by an impedance attributable to the one or more magnetostrictive resonators; a signal source configured to apply an input signal to both the first and second channels; and a signal receiver configured to generate a combined output signal in response to output signals measured from both the first and second channels. | 2016-02-25 |
20160054270 | METHOD AND SYSTEM FOR BURIED LAND MINE DETECTION THROUGH DERIVATIVE ANALYSIS OF LASER INTERFEROMETRY - A method of detecting land mines includes pre-processing a raw laser interferometer image, processing pre-processed image by calculating one or more derivatives having one or more peaks, along vectors extending in at least two different directions, mapping the peaks of said derivatives to create a derivative map, and detecting an anomalous signature in the derivative map. | 2016-02-25 |
20160054271 | SENSOR SELF-TEST - A crystal self-test circuit is used to self-test either an acoustic emission crystal or a vibration crystal installed onto one of a bearing, a bearing housing, and a machine. A crystal self-test circuit includes a multiplexer IC, which toggles between a pulse injection configuration and a signal collection configuration. In the pulse injection configuration, the multiplexer IC provides signal communication between a crystal self-test input and the sensing emission crystal. In the signal collection configuration, the multiplexer IC provides signal communication between the sensing emission crystal and a signal analyzer. In operation, the multiplexer IC applies a waveform (preferably a square wave) to the sensing emission crystal over a predetermined time period. The multiplexer IC then toggles to collect the output waveform from the sensing emission crystal and forwards the output waveform to the signal analyzer. The output signal can be amplified by a signal amplifier. | 2016-02-25 |
20160054272 | Liquid Delivery Device and Chemical Analysis Apparatus Using Liquid Delivery Device - A chemical analysis apparatus includes a liquid delivery device and a liquid discharge unit discharging the delivered first liquid and second liquid, the liquid delivery device including: a first liquid delivery unit delivering a first liquid containing an analysis object; a second liquid delivery unit delivering a second liquid not containing an analysis object; a measurement unit measuring physical properties of the delivered first liquid; a liquid pool containing the delivered first and second liquid; and a plurality of passive valves. The liquid pool includes first and second liquid pools. The apparatus further includes: a first flow passage connecting the first liquid delivery unit and the liquid delivery device; a second flow passage connecting the measurement unit and the second liquid pool; a third flow passage connecting the second liquid, delivery unit and the liquid discharge unit; a first air hole provided in the first liquid pool; and a second air hole provided in the second liquid pool. The passive valves include first and second passive valves disposed between one end of the first liquid pool and the third flow passage and between the other end of the first liquid pool and one end of the second liquid pool, respectively. | 2016-02-25 |
20160054273 | TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY SYSTEM FOR HEART-CUT METHOD - Provided is a two-dimensional liquid chromatography system, and more particularly, a two-dimensional liquid chromatography system capable of performing both independent one-dimensional separation through a reversed-phase or normal-phase chromatography method and two-dimensional separation for removing a matrix effect in a single system. | 2016-02-25 |
20160054274 | INJECTOR SAMPLE DILUTION FOR A LIQUID CHROMATOGRAPHY SYSTEM - Described are a method and a system for diluting a sample at a location of injection in a liquid chromatography system. The method includes loading a sample into a first fluid channel, separating a flow of a mobile phase into a first flow in the first fluid channel and a second flow in a second fluid channel, and combining the sample that is displaced from the first fluid channel and the mobile phase exiting the second fluid channel at the location of injection into the system flow to thereby generate a diluted sample in the system flow. The dilution ratio of the diluted sample is responsive to the flow rates of the first and second flows. Advantageously, the flow rates can be changed by changing the flow restriction of one of the fluid channels. Thus providing the proper flow restriction enables a user to obtain a desired dilution ratio. | 2016-02-25 |
20160054275 | METHOD FOR EXTENDING THE DYNAMIC RANGE OF ABSORBANCE DETECTORS - The invention generally provides methods for improving the dynamic range of an absorbance detector and absorbance detectors having improved dynamic range. In an exemplary embodiment, the method includes receiving calibration data for a plurality of samples, the calibration data comprising an absorbance for a concentration of each of the samples, calculating a contribution of stray light to the calibration data, and correcting subsequent data by removing the contribution of stray light. | 2016-02-25 |
20160054276 | METHOD FOR ESTABLISHING SHENQI FUZHENG INJECTION FINGERPRINT SPECTRUM - A method for establishing a Shenqi Fuzheng injection fingerprint spectrum, comprising: employing an ultra-high voltage liquid chromatography mass spectrometer to test the Shenqi Fuzheng injection, the chromatography conditions including: chromatographic column: Agilent Zorbax Eclipse Plus C18, 2.1 mm×100 mm, 1.8 μm; mobile phase: mobile phase A is 0.1% formic acid aqueous solution, and mobile phase B is 0.1% formic acid acetonitrile solution; employing gradient elution procedure as follows: 0-0.5 min, 95% of mobile phase A, and 5% of mobile phase B; 0.5-10 min, 95%-75% of mobile phase A, and 5%-25% of mobile phase B; 10-15 min, 75%-45% of mobile phase A, and 25%-55% of mobile phase B; 15-18 min, 45%-0% of mobile phase A, and 55%-100% of mobile phase B; and 18-20 min, 0% of mobile phase A, and 100% of mobile phase B. | 2016-02-25 |
20160054277 | HYDROGEN SENSOR AND METHOD FOR MANUFACTURING THE SAME - A hydrogen sensor and a method for manufacturing the same are provided. The hydrogen sensor includes a metal oxide layer formed over a substrate, and a catalytic pattern that is formed over the metal oxide layer. Further, a protective layer is formed over the catalytic pattern. | 2016-02-25 |
20160054278 | DEVICE TO ADJUST GAS CONCENTRATION IN FLUIDS - A device to adjust concentration of a first gas in a fluid to a target concentration (C | 2016-02-25 |
20160054279 | Method for Detecting Second and Thirdhand Smoke - A novel method for testing if smoking has occurred within a space. Smoking is determined to have happened by testing for and confirming the presence of nicotine using a lateral flow test strip. The nicotine may be captured from secondhand smoke by exposing the condensing pad of the lateral flow tester to air within the space prior to activating the test strip. The nicotine may also be captured as part of thirdhand smoke residue on a surface within the space. A prior art commercially available lateral flow test strip used to test for the presence of cotinine within a biological sample, is used in novel ways for detecting for the past presence of nicotine smoke within a space. Improvements to the test apparatus are also disclosed. | 2016-02-25 |
20160054280 | PUBLIC USE WATER TESTING KIOSK - Implementations of a public use water testing kiosk. Aspects associated with particular implementations of a water testing kiosk comprise, among others, automatically testing water based on user wants or issues, receiving a water sample for testing from the individual, providing a closeable door between the water testing and the user while the water is being tested, returning the water sample container to the user housing for the kiosk may surround all of the system parts or may be split into a housing shell and a testing unit that is inside the shell. Testing implements may be cuvette based, test strip based, probe based or other. | 2016-02-25 |
20160054281 | OPTICAL SENSOR FOR FLUID ANALYSIS - A sensor for measuring a concentration of a particular ion, molecule or atom in a fluid includes a sample handling portion for providing at least some of the fluid, a first photo-detection device, and a first light source. The first photo-detection device is configured to measure a power of light incident thereon, and the first light source includes a solid-state light emitting device. The first light source is configured to emit light having a wavelength less than 240 nanometers incident on the fluid provided by the sample handling portion, and the first photo-detection device is configured to receive light having passed through the fluid. | 2016-02-25 |
20160054282 | LANCE AND METHOD FOR DETERMINING REACTION DATA OF THE COURSE OF A REACTION - A lance and a method determine reaction data of the course of a reaction, in which a reaction gas is top-blown by at least one lance onto a metallic melt in a metallurgical vessel and measured data are determined in this way, reaction data for the course of the reaction are determined as a function of these, where the lance for determining measured data blows out a gas which is conveyed separately from the reaction gas through at least one outlet opening of at least one measuring conduit. The lance for determining measured data blows out the gas which is conveyed separately from the reaction gas laterally through at least one outlet opening of at least one measuring conduit and the internal pressure of at least one gas bubble of this gas formed at this outlet opening of the respective measuring conduit is measured. | 2016-02-25 |
20160054283 | A SOIL COMPACTION SYSTEM AND METHOD - The invention relates to a method of, and system ( | 2016-02-25 |
20160054284 | Method And System For Obtaining Geochemistry Information From Pyrolysis Induced By Laser Induced Breakdown Spectroscopy - A method for determining geochemistry of at least one geological sample with laser-induced breakdown spectral measurements performed on the geological sample in a time variant manner with spectral acquisitions made after each of a plurality of measurement shots, spectral pre-processing performed as necessary, and subsequent analysis is applied to the collected data to determine at least one geochemistry parameter of the sample. The method can provide a rapid method to estimate thermal maturity of a sample, which does not require sample preparation, and which can be non-destructive with respect to portions of the sample. A system for performing the method also is provided. | 2016-02-25 |
20160054285 | IMPLEMENTATION CONCEPTS AND RELATED METHODS FOR OPTICAL COMPUTING DEVICES - Various implementations of optical computing devices are described herein which include a “tuning fork” probe, “spark plug” probe, “grooved tubular” and “modular” type implementation. | 2016-02-25 |
20160054286 | Hydrogen sensor, hydrogen detection system employing the same, and electrical device with a hydrogen detection system - An optical sensor for detecting hydrogen in a fluid in physical contact with the sensor is provided. The sensor includes an optical fiber, wherein an end portion of the optical fiber is coated with a multilayer including: a sensing layer, including a film of an alloy, the alloy including Mg, Ni, and M, wherein M is at least one of Zr, Ta, and Hf, and wherein the alloy has the composition Mg | 2016-02-25 |
20160054287 | MACHINE OIL ANALYZER SYSTEM, COMPUTER PROGRAM PRODUCT AND RELATED METHODS - Various embodiments of the invention include a system having: at least one computing device at least one computing device configured to monitor a machine oil by performing actions including: determining an initial ideal remaining life for the machine oil; determining a temperature-based remaining life for the machine oil based upon a temperature measurement of the machine oil; calculating a contamination factor of the machine oil based upon a contamination sample of the machine oil; determining an updated ideal life remaining for the machine oil based upon the contamination factor, the initial ideal remaining life, and the temperature-based remaining life; and determining an actual life remaining for the machine oil based upon the updated ideal life remaining and a life loss factor. | 2016-02-25 |
20160054288 | WIND TURBINE LUBRICATING OIL ANALYZER SYSTEM, COMPUTER PROGRAM PRODUCT AND RELATED METHODS - Various embodiments of the invention include a system having: at least one computing device configured to monitor a lubrication oil from a wind turbine by performing actions including: determining an initial ideal remaining life for the lubrication oil from the wind turbine; determining a temperature-based remaining life for the lubrication oil based upon a temperature measurement of the lubrication oil; calculating a contamination factor of the lubrication oil based upon a contamination sample of the lubrication oil; determining an updated ideal life remaining for the lubrication oil based upon the contamination factor, the initial ideal remaining life, and the temperature-based remaining life; and determining an actual life remaining for the lubrication oil based upon the updated ideal life remaining and a life loss factor. | 2016-02-25 |
20160054289 | INDUSTRIAL MACHINE LUBRICATING OIL ANALYZER SYSTEM, COMPUTER PROGRAM PRODUCT AND RELATED METHODS - Various embodiments of the invention include a system having: at least one computing device configured to monitor a lubrication oil from an industrial machine by performing actions including: determining an initial ideal remaining life for the lubrication oil from the industrial machine; determining a temperature-based remaining life for the lubrication oil based upon a temperature measurement of the lubrication oil; calculating a contamination factor of the lubrication oil based upon a contamination sample of the lubrication oil; determining an updated ideal life remaining for the lubrication oil based upon the contamination factor, the initial ideal remaining life, and the temperature-based remaining life; and determining an actual life remaining for the lubrication oil based upon the updated ideal life remaining and a life loss factor. | 2016-02-25 |
20160054290 | TRANSPORTATION MACHINE LUBRICATING OIL ANALYZER SYSTEM, COMPUTER PROGRAM PRODUCT AND RELATED METHODS - Various embodiments of the invention include a system having: at least one computing device configured to monitor a lubrication oil from a transportation machine by performing actions including: determining an initial ideal remaining life for the lubrication oil from the transportation machine; determining a temperature-based remaining life for the lubrication oil based upon a temperature measurement of the lubrication oil; calculating a contamination factor of the lubrication oil based upon a contamination sample of the lubrication oil; determining an updated ideal life remaining for the lubrication oil based upon the contamination factor, the initial ideal remaining life, and the temperature-based remaining life; and determining an actual life remaining for the lubrication oil based upon the updated ideal life remaining and a life loss factor. | 2016-02-25 |
20160054291 | RECIPROCATING ENGINE LUBRICATING OIL ANALYZER SYSTEM, COMPUTER PROGRAM PRODUCT AND RELATED METHODS - Various embodiments of the invention include a system having: at least one computing device configured to monitor a lubrication oil from a reciprocating engine by performing actions including: determining an initial ideal remaining life for the lubrication oil from the reciprocating engine; determining a temperature-based remaining life for the lubrication oil based upon a temperature measurement of the lubrication oil; calculating a contamination factor of the lubrication oil based upon a contamination sample of the lubrication oil; determining an updated ideal life remaining for the lubrication oil based upon the contamination factor, the initial ideal remaining life, and the temperature-based remaining life; and determining an actual life remaining for the lubrication oil based upon the updated ideal life remaining and a life loss factor. | 2016-02-25 |
20160054292 | STORED LUBRICATING OIL ANALYZER SYSTEM, COMPUTER PROGRAM PRODUCT AND RELATED METHODS - Various embodiments of the invention include a system having: at least one computing device configured to monitor a lubrication oil from a lubrication oil storage system by performing actions including: determining an initial ideal remaining life for the lubrication oil from the lubrication oil storage system; determining a temperature-based remaining life for the lubrication oil based upon a temperature measurement of the lubrication oil; calculating a contamination factor of the lubrication oil based upon a contamination sample of the lubrication oil; determining an updated ideal life remaining for the lubrication oil based upon the contamination factor, the initial ideal remaining life, and the temperature-based remaining life; and determining an actual life remaining for the lubrication oil based upon the updated ideal life remaining and a life loss factor. | 2016-02-25 |
20160054293 | Prenatal Screening - The present invention relates to a method for screening maternal urine samples for changes in the pattern of mass spectral fingerprinting which have been found to be characteristic of fetal aneuploidies such as Down's Syndrome and have application for the screening of other fetal abnormalities and disorders of pregnancy including gestational trophoblastic diseases. | 2016-02-25 |
20160054294 | BREATH ANALYSER AND DETECTION METHODS - A measurement device for measuring a concentration of a component of a gas mixture includes a chamber that contains the gas mixture, a light source that emits light into the chamber, the emitted light having a wavelength between 230 nm and 320 nm, and a light sensor that detects a portion of the light from the light source that has propagated through the gas mixture. A processor is configured to determine the concentration of the component of the gas mixture based on the portion of the light emitted from the light source that is detected by the light sensor. The light source may include one or more LEDs, each having a central wavelength of light emission between 270 nm and 320 nm and a linewidth of less than 50 nm. The device may be employed to determine acetone concentration in exhaled breath, which may be indicative of diabetes or other health conditions. | 2016-02-25 |
20160054295 | APPARATUS AND METHOD FOR ANALYZING BREATH GAS MIXTURE FOR HALITOSIS DETECTION - An apparatus for detecting and separating specific compounds in breath gas mixtures for halitosis analysis consisting of a line ( | 2016-02-25 |
20160054296 | PRE-CALIBRATED REPLACEABLE SENSOR MODULE FOR A BREATH ALCOHOL TESTING DEVICE - The present invention describes a replaceable breath alcohol sensor module that can be replaced with a new pre-calibrated breath alcohol sensor module or re-calibrated. The breath alcohol sensor module requiring calibration can be removed from the body of a Breath Alcohol Testing Device (commonly called “breathalyser” or “breathalyzer”). The breath alcohol sensor module can be separately calibrated for accurate calculation of “percent blood alcohol concentration” (% BAC) based on breath air samples and then re-installed into the breath alcohol tester or the old breath alcohol sensor module can be replaced with a new pre-calibrated breath alcohol sensor module. The present invention improves upon and/or replacing the current method of re-calibration at a breathalyzer service center. | 2016-02-25 |
20160054297 | METHOD AND APPARATUS FOR DETECTING BREATH ALCOHOL CONCENTRATION BASED ON ACOUSTIC BREATH SAMPLER - An apparatus for detecting gaseous components in a breath, including a breath channel for receiving breath, a gas sensor and a flow sampler made with a vortex whistle flow-meter. Measuring the volume passed through the breath channel, and recovering the gaseous component concentration from the gas sensor reading and from the sampler reading. | 2016-02-25 |
20160054298 | High Throughput Screen - The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane. | 2016-02-25 |
20160054299 | PERFORIN 2 DEFENSE AGAINST INVASIVE AND MULTIDRUG RESISTANT PATHOGENS - Perforin-2 (P2) is expressed by fibroblasts, microglia and macrophages and was found to be responsible for killing bacteria, for example, | 2016-02-25 |
20160054300 | REFERENCE STANDARD FOR DIAGNOSTIC APPLICATIONS - We disclose a reference standard for a detectable entity, the reference standard comprising a support medium, preferably an embedding medium, a compact particle having a compact shape with a quantity of detectable entity coupled thereto and supported by the medium, in which the compact particle is a biological, preferably cellular compact particle, preferably a cellular compact particle. We also disclose a reference standard for a detectable entity, the reference standard comprising a support medium, preferably an embedding medium, a compact particle having a compact shape with a quantity of detectable entity coupled thereto and supported by the medium, in which the compact particle is a non-biological compact particle, preferably a non-cellular compact particle having cell-like dimensions, preferably less than 1.5 mm. | 2016-02-25 |
20160054301 | BIOLOGICAL ASSAY OF PEPTIDOGLYCANS - The present invention relates to a biological method for assaying peptidoglycans (PGN) in a sample, particularly a sample of glucose polymers. The PGN assay includes: a) treating the glucose polymer sample by sonication, heating, and/or alkalizing; b) placing the treated sample or a dilution thereof in contact with a recombinant cell expressing an exogenous TLR2 (toll-like receptor 2) and a reporter gene directly dependent on the signaling pathway associated with the TLR2. The reporter gene codes for a colored or fluorescent protein or for a protein the activity of which is measurable with or without a substrate; c) measuring the reporter gene signal; and d) determining the amount of PGN in the sample using a standard curve of the correlation between the amount or PGN and the strength of the reporter gene signal. | 2016-02-25 |
20160054302 | ARRAYS AND METHODS FOR GUIDED CELL PATTERNING - Guided cell patterning arrays for single cell patterning are disclosed. The arrays include a plurality of cell adhesion sites that are individually isolated on an inert surface. Each cell adhesion site has one or more cell adhesion peptides having affinity to a cell surface receptor. The inert surface is resistant to cell adhesion. | 2016-02-25 |
20160054303 | COMPOSITIONS AND ASSAYS FOR DETERMINING CELL VIABILITY - Provided are compositions and methods useful in evaluation of cell health and metabolism, cell viability, proliferation, and the effects of compounds on these qualities. The assays provided are rapid, robust, nontoxic and suitable for use with high throughput devices. | 2016-02-25 |
20160054304 | MOLECULAR TARGETS AND COMPOUNDS, AND METHODS TO IDENTIFY THE SAME, USEFUL IN THE TREATMENT OF FIBROTIC DISEASES - The present invention relates to methods and assays for identifying agents useful in the treatment of fibrotic conditions. The invention provides polypeptide and nucleic acid TARGETs, siRNA sequences based on these TARGETs and antibodies against the TARGETs. The invention is further related to pharmaceutical composition comprising siRNA sequences based on the TARGETs and antibodies against the TARGETs for use in the treatment of fibrotic conditions. The invention further provides in vitro methods for reduction or inhibition of macrophage differentiation into alternatively-activated macrophages (M2). | 2016-02-25 |
20160054305 | Method for Measuring Bile Salt Export Transport and/or Formation Activity - A method is provided to measure modulation of bile salt export transport and/or formation activity in hepatocyte or stable cell line preparations by test agents including but not limited to drugs, drug candidates, biologicals, food components, herb or plant components, proteins, peptides, DNA, RNA. Furthermore, the method is to determine modulation of bile salt export transport and/or formation activity not only by said test agents, but further their metabolites or biotransformed products formed in situ. The bile salt export transport and/or formation activity modulation includes but not limited to inhibition, induction, activation and/or regulation. The method can be practiced to identify test agents, which have potential to cause liver injury, drug-drug interactions, and/or can be used as therapeutic agents for the treatment of cholestasis, abnormality of bile salt metabolism, liver diseases and cholesterol abnormality. | 2016-02-25 |
20160054306 | The cause and possible treatment of thyroid anti-body disease - The discovery presents the means for confident diagnosis of chronic inflammatory disease of ovaries such as PID. The hormone producing function of ovaries is one of the main functions of them and if that function is disrupted, it could have the meaning that present is the condition of ovaries that requires treatment. | 2016-02-25 |
20160054307 | LED ASSAY READER WITH TOUCHSCREEN CONTROL AND BARCODE SAMPLE ID - Assay devices, assay detection systems, and methods comprising same for analytical tests, medical assays, diagnostic tests, medical diagnosis, risk assessment, or quality control purposes are provided. These devices, systems, and methods are designed to be employed at the point of care, such as in emergency rooms, operating rooms, hospital laboratories and other clinical laboratories, doctor's offices, in the field, or in any situation in which a rapid and accurate result is desired. The systems and methods process samples, such as clinical, biological, or blood sample, and read data from colorimetric based biochemical assays to provide an indication of the presence or absence of a bacterial, fungal, or viral contaminants therein. The assay devices include an optical reader apparatus and barcode scanner for reading and matching the test results to identification information provided by the barcodes to facilitate ease of tracking compliant and noncompliant samples. | 2016-02-25 |
20160054308 | SYSTEM AND METHOD FOR ITERATIVE DETECTION OF BIOLOGICAL MOLECULES - A system for the iterative detection of biological molecules includes a probe, and a fluorophore tethered to the probe with an azide-based linker. The linker is configured to be cleaved in the presence of tris(2-carboxyethyl)phosphine (TCEP), and the on/off ratio between a signal measured before treatment with TCEP and a signal measured after treatment with TCEP is at least about 20:1. | 2016-02-25 |
20160054309 | Polymer Conjugate Enhanced Bioassays - Modified branched polymers are combined with bioactive agents which are one member of a binding pair for use in an assay. | 2016-02-25 |
20160054310 | BIOSENSORS UTILIZING INK JET-PRINTED BIOMOLECULE COMPATIBLE SOL GEL INKS AND USES THEREOF - Novel solid-phase biosensors that utilize ink jet printing of biocompatible sol-gel based inks to create sensor strips are reported herein. Biomolecules and other reagents useful in bioassays to detect, for example, pathogenic microorganisms or toxic substances, are immobilized on a substrate, which can be paper based, by layering these substances between two layers of biomolecule compatible sol gel. The sol gel precursor solutions and solutions of the assay reagents are printed from separate nozzles in a layered approach which avoids clogging of the nozzles by the pre-mature gelling of the sol gel precursor solution. In certain embodiments of the application, a capture agent is used to concentrate a compound to be detected in specific areas on the substrate to facilitate detection. | 2016-02-25 |
20160054311 | ELECTROCHEMICAL LATERAL FLOW BIOASSAY AND BIOSENSOR - The electrochemical lateral flow biosensor (ELFB) comprising a novel ELFB strip and electronic detector unit, to which said strip is connected using cable or wirelessly. The strip is made of (a) polymeric hydrophobic membrane, wherein said membrane provides a solid support and enables the capillary flow along the strip; (b) conjugation pad, wherein said pad is placed over and in contact with said membrane at one end of the strip and contains formulation of the adsorbed dehydrated labelled conjugate particles, wherein said conjugate particles are coated with the biorecognition element of the assay and coated or filled with the electrochemically active component (EAC); (c) sampling pad, wherein said pad is placed on top of and in contact with said conjugation pad and provides adsorption of the liquid sample; (d) screen-printed electrode (SPE), wherein said electrode is coated with the immobilised capture antibodies; and (e) wick pad, wherein said pad is placed on top and in contact with said SPE and provides absorption of excess reagents maintaining a lateral flow along the strip. The ELFB can be used for rapid and early detection and quantity analysis of bacterial, parasitic, viral infections, and tumours in biological liquids, toxins, mycotoxins, explosives and other pollutants in wastewater. | 2016-02-25 |
20160054312 | CHEMICALLY DIFFERENTIATED SENSOR ARRAY - A chemically differentiated sensor array system includes a plurality of environmentally-gated transistors and an environmental gate, wherein the environmental gate includes a liquid solution and each environmentally-gated transistor includes a drain, a source, and a Carbon-based substrate channel, the drain electrically couples to a first location on the substrate channel, the source electrically couples to a second location on the substrate channel separated by a gap from the first location on the substrate channel, the environmental gate covers and contacts the substrate channel, a first insulating layer covers and separates the drain from the environmental gate, and a second insulating layer covers and separates the source from the environmental gate. | 2016-02-25 |
20160054313 | PEPTIDES, DEVICES, AND METHODS FOR THE DETECTION OF EHRLICHIA ANTIBODIES - The invention provides peptide compositions and mixtures useful for the detection of antibodies that bind to | 2016-02-25 |
20160054314 | VIRUS-MICROBEAD COMPLEX AND USE THEREOF - The present invention relates to a virus-microbead complex including a microbead and a virus layer, in which linear viruses are bound individually to the surface of the microbead, and an immunoassay kit including the same. | 2016-02-25 |
20160054315 | NANOELECTRONIC-ENZYME LINKED IMMUNOSORBENT ASSAY SYSTEM AND METHOD - The present invention relates to a device and method for determining the presence of a specific compound in solution. The device includes a nanosensor having an electrically conducting pathway between at least a first and second contact. The device also includes a first receptor, suitable for binding a specific compound in the solution, attached to the nanosensor, and a second receptor also suitable for binding the specific compound while the specific compound is bound to the first receptor. The second receptor is attached to an enzyme added to the solution. When the solution having the second receptor is added to the device, and a second compound that is a substrate for the enzyme is subsequently added to the solution, a measured difference in an electrical property in the device before and after the application of the second compound is indicative of the presence of the specific compound in the solution. | 2016-02-25 |
20160054316 | SYSTEM AND APPARATUS FOR POINT-OF-CARE DIAGNOSTICS - A system comprised of an apparatus and a test device is described. The test device and the apparatus are designed to interact to determine the presence or absence of an analyte of interest in a sample placed on the test device. | 2016-02-25 |
20160054317 | ASSAY WITH INCREASED DYNAMIC RANGE - Provided herein are assays and kits useful for avoiding “prozone phenomenon” or “hook effect” and which expand the range of accurately measurable analyte concentrations. | 2016-02-25 |
20160054318 | METHOD FOR THE DIAGNOSIS OF NEUROMYELITIS OPTICA - The present invention relates to a method for the diagnosis and/or risk stratification of neuromyelitis optica (abbreviated NMO), wherein a determination from a body sample of a patient/test subject is performed by means of artificial aquaporin-4 peptides. The invention further relates to a kit and to new artificial aquaporin-4 peptides as such. | 2016-02-25 |
20160054319 | METHOD FOR DETECTING TRICHOPHYTONS AND ASSOCIATED DISEASES - A method is described for detecting the presence of at least one | 2016-02-25 |
20160054320 | Markers for Determination of Patient Responsiveness - Compositions and methods are provided for classification of individuals suffering from a demyelinating disease into groups that are informative of the individual's responsiveness or lack of responsiveness to treatment with a J3-interferon (IFNJ3) acting therapy. In particular, it is shown that the effective immunomodulatory treatment of demyelinating disease with IFNJ3 is associated with an increase in circulating transitional B cells in the patient. Diseases of interest include without limitation inflammatory demyelinating diseases of the central nervous system, e.g. multiple sclerosis, neuromyelitis optica (NMO), experimental autoimmune encephalitis (EAE), acute disseminated encephalomyelitis (ADEM), etc. | 2016-02-25 |
20160054321 | Methods For Detecting Human Metapneumovirus - The present invention discloses specific human metapneumovirus monoclonal antibodies. The antibody is at least two-fold less reactive with non-human metapneumoviruses including, but not limited to, respiratory viruses or avian metapneumoviruses. Further, the antibody is at least two-fold more reactive with a human metapneumovirus (i.e., for example, Type A or Type B) than with non-human metapneumoviruses including, but not limited to, respiratory viruses or avian metapneumoviruses. Consequently, these novel antibodies are useful as a clinical diagnostic agent, especially when using fresh nasopharengeal aspirates. The invention also contemplates numerous diagnostic platforms that together with the novel antibodies can support economical, fast, and highly selective detection and identification of clinical inoculum samples. | 2016-02-25 |
20160054322 | HOMOGENOUS THERMAL SHIFT LIGAND BINDING ASSAY - Disclosed are methods for detecting and quantitatively measuring a binding property of a compound to a target macromolecule, wherein the target macromolecule is subject to denaturation and is linked to a labeling peptide, such as a short enzyme fragment. The method uses a fluid mixture comprising (i) a chimeric molecule comprising a target macromolecule linked to the labeling peptide and (ii) a compound being measured for binding to the target macromolecule, wherein said target macromolecule is subject to denaturation. After allowing for binding of the compound (e.g. a small molecule inhibitor of the target macromolecule), one detects a signal from the labeling peptide, such as by enzyme fragment complementation. This signal indicates a differential between denatured and non-denatured target macromolecules and thereby indicates a differential between target macromolecules not bound to the compound and target macromolecules bound to the compound, respectively. | 2016-02-25 |
20160054323 | SRM/MRM Assay for Subtyping Lung Histology - The current disclosure provides for specific peptides, and derived ionization characteristics of the peptides, from the KRT5, KRT7, NapsinA, TTF1, TP63, and/or MUC1 proteins that are particularly advantageous for quantifying the KRT5, KRT7, NapsinA, TTF1, TP63, and/or MUC1 proteins directly in biological samples that have been fixed in formalin by the method of Selected Reaction Monitoring (SRM) mass spectrometry, or what can also be termed as Multiple Reaction Monitoring (MRM) mass spectrometry. Such biological samples are chemically preserved and fixed wherein said biological sample is selected from tissues and cells treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin-fixed/paraffin embedded (FFPE) tissue/cells, FFPE tissue blocks and cells from those blocks, and tissue culture cells that have been formalin fixed and or paraffin embedded. A protein sample is prepared from said biological sample using the Liquid Tissue™ reagents and protocol and the KRT5, KRT7, NapsinA, TTF1, TP63, and/or MUC1 proteins are quantitated in the Liquid Tissue™ sample by the method of SRM/MRM mass spectrometry by quantitating in the protein sample at least one or more of the peptides described. These peptides can be quantitated if they reside in a modified or an unmodified form. An example of a modified form of a KRT5, KRT7, NapsinA, TTF1, TP63, and MUC1 fragment peptide is phosphorylation of a tyrosine, threonine, serine, and/or other amino acid residues within the peptide sequence. | 2016-02-25 |
20160054324 | ASRGL1 IN ENDOMETRIAL CANCER - There is provided a method for determining whether a mammalian subject having an endometrial cancer belongs to a first or a second group, wherein the prognosis of subjects of the first group is better than the prognosis of subjects of the second group, comprising the steps of: a) evaluating an amount of ASRGL1 in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount; b) comparing said sample value with a predetermined reference value; and if said sample value is higher than said reference value, c1) concluding that the subject belongs to the first group; and if said sample value is lower than or equal to said reference value, c2) concluding that the subject belongs to the second group. | 2016-02-25 |
20160054325 | MOLECULAR PROFILING OF TUMORS - Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a treatment for a particular disease. | 2016-02-25 |
20160054326 | RARE CELL CONCENTRATION - A ratio of rare cells to non-rare cells in a blood sample suspected of containing rare cells and non-rare cells is enhanced. A treated blood sample is prepared by providing in combination the blood sample, a platelet deactivation agent, a fibrin-formation-arresting agent and fibrin in an amount sufficient to cause a predetermined level of agglutination of the rare cells. The treated blood sample is then contacted with a porous matrix such that agglutinated rare cells are preferentially retained on the porous matrix. The rare cells may then be identified. | 2016-02-25 |
20160054327 | RAPID PROTEIN LABELING AND ANALYSIS - The present invention provides methods and compositions for labeling, separating and analyzing proteins, particularly a specific protein of interest within a cell lysate or in a mixture of proteins. The proteins are labeled with an amine reactive or thiol reactive fluorescent dye, or an amine reactive fluorogenic reagent that becomes fluorescent upon reacting to amine groups located on the protein. Following the labeling step, the proteins within the mixture can be separated and analyzed. In a further embodiment, a tag binding fluorogenic reagent that can bind to a tag on a tagged protein is added to specifically label the protein of interest. | 2016-02-25 |
20160054328 | ONE POT PROCESS FOR THE PREPRATION OF GOLD QUANTUM CLUSTERS - The invention disclosed herein provides tunable process for the preparation of water dispersive, biocompatible, fluorescent L-cystine labeled gold (Au) quantum clusters without using any toxic reactants. Further the invention discloses application of synthesized fluorescent gold (Au) quantum clusters in the field of nano-medicine, fluorescence imaging and florescence based sensors. | 2016-02-25 |
20160054329 | NOVEL SENSOR SYSTEM UTILIZING PIEZOELECTRIC MICROCANTILEVER COUPLED WITH RESONATING CIRCUIT - An interchangeable sensor system is described, including: a microcantilever including a beam anchored at a first end, the beam being free to vibrate on another end, wherein a piezoelectric layer is deposited on a surface of the beam; an input configured to receive a voltage from a voltage source for applying voltage to the piezoelectric layer; and a resonating circuit including: the piezoelectric layer, configured as a capacitor of the resonant circuit; and one or more additional electrical elements; wherein the voltage source is configured to apply a first AC voltage under a first condition for actuating the microcantilever at a first mechanical resonating frequency of the microcantilever and a second AC voltage under a second condition for actuating the microcantilever at a second electrical resonating frequency of the resonating circuit. Method of using the sensor system is also described. | 2016-02-25 |
20160054330 | BIOMARKERS FOR HYPERTENSIVE DISORDERS OF PREGNANCY - The application discloses new biomarkers for hypertensive disorders of pregnancy and particularly preeclampsia; methods for the diagnosis, prediction, prognosis and/or monitoring said disorders based on measuring said biomarkers; and kits and devices for measuring said biomarker and/or performing said methods. | 2016-02-25 |
20160054331 | METHOD FOR THE DETECTION AND/OR ENRICHMENT OF ANALYTE PROTEINS AND/OR ANALYTE PEPTIDES FROM A COMPLEX PROTEIN MIXTURE - The present invention relates to a method for the detection and/or enrichment of a large number of different analyte proteins and/or analyte peptides from a sample mixture which includes proteins and/or peptides. The method includes the following steps: a) provision of the sample mixture and, where appropriate, fragmentation of the proteins contained therein into defined peptides, b) provision of first binding molecules which are specific for a peptide epitope of at least one of the various analyte proteins and/or analyte peptides, whereby the peptide epitope includes up to a maximum of five, preferably two to three, amino acids, c) incubation of the first binding molecules with the sample mixture, and d) detection and/or enrichment of the analyte proteins and/or analyte peptides bound to the first binding molecules. The invention also relates to binding molecules which are specific for the terminal peptide epitope of various peptide analytes, whereby the terminal peptide epitope includes the free NH | 2016-02-25 |
20160054332 | MASS SPECTROMETRIC DETERMINATION OF DRUG RESISTANCE - The invention relates to a method to determine drug resistance in microbes. The method relates to measuring the drug resistance conferring protein by mass spectrometry. The mass spectrum acquired provides information whether an drug resistance conferring protein is present and information on the type of drug resistance conferring protein, on mutations of the drug resistance conferring protein as well as on the expression level of this protein. | 2016-02-25 |
20160054333 | METHOD FOR DETECTING ASYN-SPECIFIC ANTIBODIES IN A BIOLOGICAL SAMPLE - Disclosed is a method for detecting aSyn-specific antibodies in a biological sample, comprising the following steps: contacting the sample with aSyn-comprising-aggregates and allowing the aSyn-specific antibodies to bind to the aSsyn-comprising-aggregates, and detecting the aSyn-specific antibodies bound to the aSyn-comprising-aggregates by a single particle detection technique, preferably by fluorescence activated cell sorting (FACS). | 2016-02-25 |
20160054334 | FUTURE CARDIAC EVENT BIOMARKERS - The present invention relates to the identification of chemokine biomarkers predictive of future acute coronary syndromes including unstable angina pectoris (UAP). The present invention also identifies particular chemokines as potential therapeutic targets for intervention in cardiovascular diseases. | 2016-02-25 |
20160054335 | MARKER FOR DIAGNOSING AGE-RELATED MACULAR DEGENERATION, AND METHOD FOR DIAGNOSING AGE-RELATED MACULAR DEGENERATION BY USING SAME - A biomarker for diagnosing age-related macular degeneration includes a vinculin protein, and a diagnostic kit, a diagnostic method, and a method of screening a therapeutic material for age-related macular degeneration use the biomarker. The diagnostic kit and the diagnostic method of age-related macular degeneration are novel immunological diagnostic tools using the plasma of a patient, and have remarkable sensitivity that enables simple analysis of plasma without a biopsy, and thus can be useful for diagnosing age-related macular degeneration. | 2016-02-25 |
20160054336 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Clusterin, Heart-type fatty acid binding protein, Hepatocyte growth factor, Interferon gamma, Interleukin-12 subunit beta, Interleukin-16, Interleukin-2, 72 kDa type IV collagenase, Matrix metalloproteinase-9, Midkine, and Serum amyloid P-component as diagnostic and prognostic biomarkers in renal injuries. | 2016-02-25 |
20160054337 | Method for Determining Radiosensitivity - The present invention relates to a method for the in vitro determination of the radiosensitivity of a subject. More particularly, the invention relates to a method comprising a step of inducing an exogenous stress on a biological sample from a subject, followed by the comparison of the presence or level of at least one compound chosen in a group of defined compounds, in said biological sample and in a reference sample. The present invention also relates to the use of said at least one compound as predictive biomarker of the radio-sensitivity of a subject. The invention also relates to a kit for the detection of the presence or level of at least one of said compounds, usable in a method according to the invention. | 2016-02-25 |
20160054338 | Methods for Predicting Cardiovascular Mortality Risk - The present invention relates to a method for predicting cardiovascular mortality risk in a patient, comprising determining the level of endothelial microparticles in a blood sample obtained from said patient. | 2016-02-25 |
20160054339 | VALUE ASSIGNMENT FOR CUSTOMIZABLE QUALITY CONTROLS - Methods are provided for end users of diagnostic measurement procedures to prepare quality controls having desired analyte recoveries, estimate recoveries of quality controls already prepared, and compare estimated and measured recoveries. To prepare a quality control containing a particular analyte, a desired recovery of a measurement procedure for the analyte can be scaled by a correlation factor to obtain a target nominal concentration of the analyte in the quality control. Alternatively, the nominal concentration of an analyte in a quality control can be scaled by a correlation factor to obtain a predicted recovery of a measurement procedure for the analyte. The correlation factors can be based on recovery data previously obtained using the measurement procedure and optionally one or more reference procedures, and can be calculated using regression analysis of these data. Each quality control can be prepared by dissolving a number of solid beads containing the analyte(s) of interest in a volume of base matrix. | 2016-02-25 |
20160054340 | WORKFLOW TIMING BETWEEN MODULES - The invention relates to a method of isolating and analyzing an analyte using an analytical apparatus which comprises modules of different types, wherein any one module of one type has a specific, pre-defined timing for carrying out its workflow. | 2016-02-25 |
20160054341 | SAMPLE CONTAINER CARRIER FOR A LABORATORY SAMPLE DISTRIBUTION SYSTEM, LABORATORY SAMPLE DISTRIBUTION SYSTEM AND LABORATORY AUTOMATION SYSTEM - A sample container carrier, a laboratory sample distribution system comprising such a sample container carrier, and to a laboratory automation system comprising such a laboratory sample distribution system are presented. The sample container carrier can tilt a sample container in order to allow higher acceleration rates. | 2016-02-25 |
20160054342 | IN-VITRO DIAGNOSTIC APPARATUS AND IN-VITRO DIAGNOSTIC TEST METHOD - An in-vitro diagnostic apparatus includes a controller configured to set a test result reference range corresponding to a condition of a testee, among test result reference ranges corresponding to a plurality of conditions, with respect to a test item of a test object, and generate a user interface screen including the set test result reference range; and a display configured to display the user interface screen. | 2016-02-25 |
20160054343 | SYSTEMS AND METHODS FOR MULTI-ANALYSIS - Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. | 2016-02-25 |
20160054344 | LABORATORY SAMPLE DISTRIBUTION SYSTEM, LABORATORY SYSTEM AND METHOD OF OPERATING - A laboratory sample distribution system is presented. The laboratory sample distribution system comprises a plurality of container carriers. The container carriers each comprise at least one magnetically active device such as, for example, at least one permanent magnet, and carry a sample container containing a sample. The system further comprises a transport plane to carry the multiple container carriers and a plurality of electro-magnetic actuators stationary arranged below the transport plane. The electro-magnetic actuators move a container carrier on top of the transport plane by applying a magnetic force to the container carrier. The system also comprises at least one transfer device to transfer a sample item, wherein the sample item is a container carrier, a sample container, part of the sample and/or the complete sample, between the transport plane and a laboratory station such as, for example, a pre-analytical, an analytical and/or a post-analytical station. | 2016-02-25 |
20160054345 | PIPETTING SYSTEM - The present invention provides a pipette assembly and a liquid handling element employing such a pipette assembly for filling containers. The pipette assembly comprises a biasing member that prevents the containers from being displaced vertically upon withdrawal of the pipette assembly from the containers. | 2016-02-25 |
20160054346 | AXLE ASSEMBLY MAKING WHEEL SPEED MEASURING PRECISELY - An axle assembly for measuring wheel speed is provided. The axle assembly includes a knuckle having a locking jaw for a bearing formed at a position on a vehicle, the knuckle including an inner circumferential surface configured to allow the bearing to be inserted from the outside of the vehicle to the inside, a speed sensor affixed to the locking jaw, and a magnetic encoder affixed to the bearing. | 2016-02-25 |
20160054347 | ENERGY BEAM DEFLECTION SPEED VERIFICATION - A method for verifying a deflection speed of an energy beam spot, the method comprising the steps of: providing a predetermined pattern on a work table with the energy beam spot while deflecting the energy beam spot with a first deflection speed, detecting first positions of the energy beam spot on the work table created with the first deflection speed, providing the predetermined pattern on a work table with the energy beam spot while deflecting the energy beam spot with a second deflection speed, detecting second positions of the energy beam spot on the work table created with the second deflection speed, comparing the first and second positions, wherein the deflection speed is verified if each one of the first positions are deviating less than a predetermined distance from corresponding second positions. | 2016-02-25 |
20160054348 | VEHICLE WHEEL SPEED SENSOR PROTECTION STRUCTURE - In a vehicle including a pulse ring that rotates together with a wheel, a wheel speed sensor that has a detection portion close to the pulse ring, and a bracket that fixes the wheel speed sensor, a tubular protective wall surrounding the detection portion is provided on the bracket so that an end part, on the pulse ring side, of the protective wall is closer to the pulse ring than the detection portion) of the wheel speed sensor is. This enables the wheel speed sensor to be protected without adding a special component. | 2016-02-25 |