| 08th week of 2013 patent applcation highlights part 37 |
| Patent application number | Title | Published |
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| 20130045981 | ARIPIPRAZOLE COMPLEX FORMULATION AND METHOD - An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a β-cyclodextrin, preferably, sulfobutyl ether β-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided. | 2013-02-21 |
| 20130045982 | BENZAMIDE DERIVATIVES - Disclosed are benzamide derivatives useful in slowing the expansion of cancer cells including the killing of cancer cells and in the treatment of cancer. | 2013-02-21 |
| 20130045983 | HSP90 INHIBITORS FOR THERAPEUTIC TREATMENT - The use of a Hsp90 inhibitor for the treatment of cancer of the bladder, the colon, the liver, the lung, the breast, the vagina, the ovaries, the pancreas, the kidney, the stomach, the gastrointestinal tract, the prostate, the head and neck, the peritoneal cavity, the thyroid, the bone, the brain, the central nervous system and/or the blood and/or for the treatment of myelodysplastic syndrome, systemic mastocytosis, von Hippel-Lindau syndrome, multicentric Castleman disease and/or psoriasis. | 2013-02-21 |
| 20130045984 | 5-FLUORO-4-IMINO-3,4-DIHYDROPYRIMIDIN-2-(1H)-ONES DERIVATIVES - This present disclosure is related to the field of 5-fluoro-4-imino-3-(substituted)-3,4-dihydropyrimidin-2(1H)ones and their derivatives and to the use of these compounds as fungicides. | 2013-02-21 |
| 20130045985 | N-(5-FLUORO-2-((4-METHYLBENZYL)OXY)PYRIMIDIN-4-YL)BENZAMIDE DERIVATIVES - This present disclosure is related to the field of N-(5-fluoro-2-((4-methylbenzyl)oxy)pyrimidin-4-yl)benzamides and their derivatives and to the use of these compounds as fungicides. | 2013-02-21 |
| 20130045986 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 - The present invention relates to novel compounds of formula (A) and (B) as modulators of GPR-119, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of GPR-119 mediated diseases or disorders with them. | 2013-02-21 |
| 20130045987 | NOVEL METHODS OF USE OF TETRAHYDROBERBERINE (THB) - Tetrahydroberberine (THB), isolated from the Chinese herb “ | 2013-02-21 |
| 20130045988 | COMBINATION THERAPY - Described herein is a combination comprising at least one 5-HT | 2013-02-21 |
| 20130045989 | STABILIZED CRYSTAL OF 2-ETHYL-3,7-DIMETHYL-6-(4-(TRIFLUOROMETHOXY)PHENOXY)QUINOLINE-4-YL METHYL CARBONATE, PROCESS FOR PRODUCING THE CRYSTAL, AND AGRICULTURAL CHEMICAL COMPOSITION COMPRISING THE CRYSTAL - An objective of the present invention is to provide a crystal of 2-ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinoline-4-yl methyl carbonate having stable physicochemical properties. | 2013-02-21 |
| 20130045990 | NOVEL 1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVE USEFUL FOR THE TREATMENT OF DIABETES - The present invention provides a compound of the formula below | 2013-02-21 |
| 20130045991 | NEUROPROTECTIVE MODULATION OF NMDA RECEPTOR SUBTYPE ACTIVITIES - In various aspects, the invention provides methods and compositions for modulating NMDA receptor subtype activity, to enhance NR2A-containing NMDA receptor activity relative to NR2B-containing NMDA receptor activity, so as to effect a neuroprotective reduction in excitotoxic NMDA receptor activity | 2013-02-21 |
| 20130045992 | Compositions and Methods for Enhancing Proteasome Activity - Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp 14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies. | 2013-02-21 |
| 20130045993 | INHIBITORS OF CYCLIN-DEPENDENT KINASES AND THEIR USE - The present invention relates to novel compounds for the inhibition of cyclindependent kinases, and more particularly, to chromenone derivatives of formula (Ia), | 2013-02-21 |
| 20130045994 | PYRIDINE DERIVATIVE - The present invention relates to a novel pyridine derivative or a pharmacologically acceptable ester thereof, or a pharmacologically acceptable salt of the derivative or ester, which has an excellent hypoglycemic effect or treats and/or prevents the onset of a disorder of carbohydrate or lipid metabolism or a disease mediated by peroxisome proliferator-activated receptor (PPAR) γ. A compound represented by the general formula (I): | 2013-02-21 |
| 20130045995 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES - The present invention relates to hydroximoyl-heterocycle derivatives of formula (I) | 2013-02-21 |
| 20130045996 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS - The invention relates to novel compositions for controlling parasites on animals, comprising an N-arylpyrazole and also a pyrethroid in a formulation comprising aliphatic cyclic carbonates and aliphatic cyclic or acyclic polyethers. | 2013-02-21 |
| 20130045997 | PIRFENIDONE THERAPY AND INDUCERS OF OF CYTOCHROME P450 - The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking. | 2013-02-21 |
| 20130045998 | PROCESS FOR PREPARING RUFINAMIDE INTERMEDIATE - The present invention refers to an improved method for the preparation of compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid substantially free of its 3H-I isomer. The invention also refers to the use of said intermediate for the preparation of Rufinamide and for obtaining a new polymorphic form of Rufinamide, designed as Form R-5. The invention also refers to said new polymorph of Rufinamide, and to the composition containing it and its use as medicament. The new polymorph of Rufinamide shows good stability and appropriate physico-chemical properties for its manipulation on industrial scale. Polymorph Form R-5 will be suitable to use as pharmaceutical for the treatment of convulsions, especially for the treatment of epilepsy. | 2013-02-21 |
| 20130045999 | SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF - The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals. | 2013-02-21 |
| 20130046000 | COMPOUNDS FOR SUPPRESSING A PERIPHERAL NERVE DISORDER INDUCED BY AN ANTI-CANCER AGENT - The present invention provides a medicament that suppresses (or mitigates) various neurological symptoms caused by a peripheral nerve disorder induced by an anti-cancer agent. | 2013-02-21 |
| 20130046001 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION - Provided is a pharmaceutical composition for inhibiting apoptosis of neurons or neurodegeneration. The pharmaceutical composition effectively prevents or treats diseases related to apoptosis of neurons or neurodegeneration. | 2013-02-21 |
| 20130046002 | TRIAZOLE COMPOUND HAVING PESTICIDAL ACTIVITIES - To provide a triazole compound which has remarkably excellent pesticidal activities. Optically active (+)-1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole represented by the following formula (I), which is obtainable by subjecting a racemic modification of 1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole to optical resolution: | 2013-02-21 |
| 20130046003 | PHARMACEUTICAL COMPOSITIONS COMPRISING 4-BROMO-N-(IMIDAZOLIDIN-2-YLIDENE)-1H-BENZIMIDAZOL-5-AMINE FOR TREATING RETINAL DISEASES - The present invention relates to a method for treating retinal diseases and a method for retinal neuroprotection, in a patient in need thereof which comprises of administering a therapeutically effective amount of a pharmaceutical composition comprising a therapeutically effective amount of 4-bromo-N-(imidazolidin-2-ylidene)-1H-benzimidazol-5-amine or pharmaceutically acceptable salts thereof. | 2013-02-21 |
| 20130046004 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS - The present invention relates to compounds of the formula I, wherein A, D, E, G, R | 2013-02-21 |
| 20130046005 | TREATMENT OF IMMUNE DISORDERS USING KAINATE RECEPTOR ANTAGONISTS - Allergies and immune system disorders (e.g. autoimmune diseases) are treated by administration of an agent that blocks activation of the kainic acid receptor (KAR) in B cells. The agents include antagonists and weakly activating agonists. | 2013-02-21 |
| 20130046006 | INHIBITORS OF FAM3B GENE, INHIBITOR COMPOSITIONS, INHIBITING METHODS AND APPLICATIONS OF INHIBITORS IN PREPARING PHARMACEUTICALS - Inhibitors that can inhibit expression of FAM3B gene to reduce the levels of expression products, or can combine the expression products to reduce the activity of promoting lipid synthesis of FAM3B gene product are provided, wherein the inhibitors are one or more inhibitors selected from the group consisting of small interfering RNAs, antisense oligonucleotides, antibodies against FAM3B proteins and active organic compounds. Cells, vectors or inhibitor compositions, comprising such inhibitors, methods for inhibiting expression of FAM3B gene or inhibiting the activity of promoting lipid synthesis of FAM3B gene product using the inhibitors are provided. Methods for treating diseases mediated by expression of FAM3B gene using such inhibitors and uses of the inhibitors in preparing pharmaceuticals for preventing and/or treating the disease mediated by FAM3B gene expression are also provided. | 2013-02-21 |
| 20130046007 | SELECTIVE REDUCTION OF ALLELIC VARIANTS - Disclosed herein are antisense compounds and methods for selectively of reducing expression of an allelic variant of a gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate diseases, including neurodegenerative, such as Huntington's Disease (HD). | 2013-02-21 |
| 20130046008 | SELECTIVE REDUCTION OF ALLELIC VARIANTS - Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD). | 2013-02-21 |
| 20130046009 | RHO KINASE INHIBITORS FOR TREATMENT OF MASTOCYTOSIS AND ACUTE MYELOID LEUKEMIA - The disclosure is directed to methods of treating hematologic malignancies. More particularly, the disclosure is directed to methods of treating hematologic malignancies using Rho kinase (ROCK) inhibitors and myosin light chain-specific inhibitory RNA molecules. The disclosure is further directed to methods of identifying drug candidates for inhibiting ROCK in hematologic malignancies. | 2013-02-21 |
| 20130046010 | SUMO AS A MARKER OF CANCER DEVELOPMENT AND TARGET FOR CANCER THERAPY - Disclosed herein are methods relating to inhibiting or reducing proliferation of a cancer cell, for treating cancer in a subject in need of treatment, predicting the risk of progression of cancer to a more aggressive cancer, and screening for cancer in a subject, that comprise detecting and/or decreasing the levels of SUMO conjugated proteins and detecting and/or interfering with SUMO conjugation. | 2013-02-21 |
| 20130046011 | HOT-MELT EXTRUDED COMPOSITIONS CONTAINING PLANT-DERIVED PHENOLIC MATERIALS AND PROCESSES FOR THE PREPARATION THEREOF - A hot-melt extruded composition is disclosed that includes about 20-80% wt. of a plant-derived phenolic material; about 20-85% wt. of one or more edible or bioerodible excipients; about 0-40% wt. of a surface active material; about 0-40% wt. of an oral absorption enhancer; and about 0-10% wt. of one or more pharmaceutical or food grade additives. The composition has been hot-melt extruded at a temperature substantially below the melting point of the plant-derived phenolic material to produce a hot-melt extruded composition wherein substantial degradation of the plant-derived phenolic material has not occurred. | 2013-02-21 |
| 20130046012 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN - The present invention relates to compounds of formula (I), or pharmaceutically acceptable, stereoisomers, salts or solvates thereof | 2013-02-21 |
| 20130046013 | SALICYLATE FATTY ACID DERIVATIVES - Fatty acid conjugates of salicylate derivatives and compositions thereof are disclosed. Further disclosed are methods for treating various diseases comprising the administration of an effective amount of at least one compound according to the present disclosure. | 2013-02-21 |
| 20130046014 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INCREASED INTRAOCULAR PRESSURE - The invention provides novel pharmaceutical compositions for the treatment of increased intraocular pressure based on semifluorinated alkanes which are useful as carriers for a broad range of active ingredients. Preferred active ingredients include poorly water-soluble prostaglandin analogues. The compositions can be administered topically into the eye. The invention further provides kits comprising such compositions. | 2013-02-21 |
| 20130046015 | Therapeutic Inhibition of Granulocyte Function in Demyelinating Disease - Compositions and methods are provided for the treatment of IL-17-type inflammatory demyelinating diseases with inhibitors of granulocyte function, e.g. elastase inhibitors. Diseases of interest include multiple sclerosis, neuromyelitis optica, animal models of such diseases, etc. In some embodiments pharmaceutical formulations comprising an elastase inhibitor in an effective dose for treatment of IL-17-type inflammatory demyelinating disease and a pharmaceutically acceptable excipient are provided. Patients may be classified into subtypes prior to treatment, which subtypes are informative of the patient's need for therapy and responsiveness to a therapy of interest. | 2013-02-21 |
| 20130046016 | METHOD FOR LOWERING CHOLESTEROL - The present invention relates to a method of lowering cholesterol in a patient in need thereof by administering to said patient a therapeutic effective amount of a compound selected from the group of Dihydroxyacetone phosphate (DHAP); 1-acyl-DHAP; 1-alkyl-DHAP; 1-alkyl-glyceraldehyde-3-phosphate (G3P); 1-alkyl, 2-acyl-G3P; 1-alkyl, 2-acyl-glycerol; 1-alkyl,2-acyl-glycerylphosphatidylethanolamine (GPE), 1-alkyl, diacyl glycerol (sn-1=16:0, sn-2=docosohexaenoic acid (DHA); sn-3=DHA) (sn-1 position has an alkyl ether bond, sn-2 and sn-3 positions have acyl bonds); 1-alkyl diacyl glycerol (sn-1=16:0, sn-2=18:1, sn-3=18:1) (sn-1 position has an alkyl ether bond, sn-2 and sn-3 positions have acyl bonds); triacyl glycerol (sn-1=16:0, sn-2=DHA, sn-3=DHA) (all three positions have acyl bonds); and triacyl glycerol (sn-1=16:0, sn-2=18:1, sn-3=18:1) (all three positions have acyl bonds) and pharmaceutically acceptable salts thereof. | 2013-02-21 |
| 20130046017 | COMPOUNDS PROVIDED WITH ANTIOXIDANT ACTIVITY AGAINST FREE RADICALS, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM - The invention relates to the use of compounds of general formula (I): | 2013-02-21 |
| 20130046018 | DIETARY SUPPLEMENTS CONTAINING TERPENOID ACIDS OF MASLINIC ACID OR OLEANOLIC ACID AND PROCESS FOR ENHANCING MUSCLE MASS IN MAMMALS - A process for increasing lean body mass in a mammalian subject is provided that includes administering to the subject a purified quantity of maslinic acid, oleanolic acid, or a combination thereof. The administration can be orally and benefits from ingestion of an amino acid source such as dietary protein, oligopeptides, or amino acids. Administration within 2 hours of muscle-degrading exercise or on a daily basis for a period of time increases lean body mass. | 2013-02-21 |
| 20130046019 | Methods of Treatment Using 3-Bromopyruvate and Other Selective Inhibitors of ATP Production - The present invention provides methods for preventing or treating infections, especially bacterial infections, by administering selective inhibitors of ATP production to inhibit glycolytic enzymes, such as glyceraldehyde 3-phosphate dehydrogenase (GAPDH). As such, the present invention further provides methods for preventing or treating inflammation and sepsis associated with infections, as well as increased wound healing and decreased wound scarring. | 2013-02-21 |
| 20130046020 | EICOSAPENTAENOIC ACID CONCENTRATE - An omega-3 oil concentrate comprising at least 70 weight percent of eicosapentaenoic acid [“EPA”; cis-5,8,11,14,17-eicosapentaenoic acid; omega-3], measured as a weight percent of oil, and substantially free of docosahexaenoic acid, said concentrate obtained from a microbial oil having 30 to 70 weight percent of eicosapentaenoic acid, measured as a weight percent of total fatty acids, and substantially free of docosahexaenoic acid and wherein said microbial oil is obtained from a microorganism that accumulates in excess of 25% of its dry cell weight as oil. Also disclosed are methods of making such eicosapentaenoic acid concentrates. | 2013-02-21 |
| 20130046021 | METHODS OF TREATING CARDIOMYOPATHY, SYSTOLIC CARDIAC DYSFUNCTION AND THE SYMPTOMS OF CONGESTIVE HEART FAILURE WITH PROBENECID - Described herein are inventions is directed to methods of treating a cardiac dysfunction and symptoms of cardiac dysfunction in a subject that includes administering an amount of probenecid effective to treat a symptom of cardiac dysfunction. The probenecid may be administered in at least one of an injection, orally, or transdermally. The amount of probenecid is sufficient to result in an improved performance on a standardized 6 minute walk test, an improved New York Heart Association (NYHA) classification, a lower diuretic dose requirement, a lower serum BNP levels, a normalization of serum sodium concentrations, and combinations thereof In an embodiment, probenecid is administered over a period of about 8 hours to about 24 hours. Probenecid may be used for short term treatments, i.e., less than a week, or it may be administered in a long term manner, i.e., over a period of weeks, months, or even years. Probenecid may be administered in an amount sufficient to treat the symptoms of cardiac dysfunction. | 2013-02-21 |
| 20130046022 | GEL COMPOSITION FOR TREATMENT OF COMMON ACNE COMPRISING A COMBINATION OF BENZOYL PEROXIDE AND ADAPALENE AND/OR ADAPALENE SALT - Dermatological/cosmetic compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including preventing or treating common acne, comprise, in a physiologically acceptable medium, (i) at least one dispersed retinoid, (ii) dispersed benzoyl peroxide, in free or encapsulated form, and (iii) at least one pH-independent gelling agent, selected from the group consisting of (a) polyacrylamide gelling agents, (b) gelling agents which are acrylic polymers coupled to hydrophobic chains, (c) modified starch gelling agents, and mixture thereof, said composition maintaining good chemical stability of (i) and (ii) without their degradation over time at a temperature of between 4° C. and 40° C. | 2013-02-21 |
| 20130046023 | PHARMACEUTICAL COMPOSITION CONTAINING GLUR2-LACKING AMPAR ANTAGONIST FOR PREVENTING OR TREATING PSYCHIATRIC ILLNESSES - A pharmaceutical composition, comprising a GluR | 2013-02-21 |
| 20130046024 | COMPOSITION, METHOD AND KIT FOR ENHANCING HAIR - Compositions for application and methods of application of a composition to modify hair. In one embodiment, a composition includes a compound (molecule) represented by: | 2013-02-21 |
| 20130046025 | COMPOSITION WITH LOW SKIN IRRITATION FOR TRANSDERMAL DELIVERY OF TOLTERODINE - Disclosed is a composition for transdermal administration containing tolterodine. The composition comprises at least one essential oil as an abirritant to minimize skin irritation caused by tolterodine. The composition relieves skin irritation caused by tolterodine. Therefore, a successful commercial application of a tolterodine-containing transdermal preparation based on the composition can be expected. | 2013-02-21 |
| 20130046026 | COMPOSITION WITH IMPROVED SKIN PENETRATION FOR TRANSDERMAL DELIVERY OF TOLTERODINE - Disclosed is a composition for transdermal administration containing tolterodine. The composition comprises lidocaine or a pharmaceutically acceptable salt thereof to achieve enhanced skin penetration. The composition enhances the skin penetration of tolterodine. Therefore, a successful commercial application of a tolterodine-containing transdermal preparation based on the composition can be expected. | 2013-02-21 |
| 20130046027 | CHOCOLATE WITH AGGLOMERATE STRUCTURE AND THE METHOD FOR PREPARING THEREOF - The present invention relates to a method for preparing chocolate with agglomerate structure. It also relates to the chocolate obtained by said method characterized in that has the organoleptic characteristics of the conventional chocolate, it is physico-chemically stable at a temperature greater than or equal to 40° C., maintains its flowability at a temperature of up to 50° C. and is crunchy. | 2013-02-21 |
| 20130046028 | Cosmetic Raw Material - A cosmetic raw material comprising the following components (A), (B), and (C): (A) a specific polyether-modified organopolysiloxane; (B) a chain-form silicone oil that is a liquid at 25° C., does not contain a cyclic structure, and does not contain a resinous structure; and (C) an oil that is a liquid at 30° C. and that characteristically (c1) has at least one hydroxyl group in each molecule, (c2) has from 0 to 3, as the number of moles of addition, oxyethylene units in each molecule, (c3) has an HLB value in the range from 0.1 to 6.0, and (c4) has an average molecular weight in the range from 200 to 7000. | 2013-02-21 |
| 20130046029 | ANTI-ULTRAVIOLET ADDITIVE COMPRISING A UVA FILTER, A UVB FILTER AND AN OIL THAT IS A SOLVENT FOR SAID FILTERS, AND USE THEREOF IN COLOURED AND/OR PERFUMED COMPOSITIONS - The invention relates to an additive comprising at least 95 wt. % of a mixture consisting of at least one organic filter filtering UV | 2013-02-21 |
| 20130046030 | CONTROL OF EMULSIONS, INCLUDING MULTIPLE EMULSIONS - The present invention generally relates to emulsions, and more particularly, to double and other multiple emulsions. Certain aspects of the present invention are generally directed to the creation of double emulsions and other multiple emulsions at a common junction of microfluidic channels. In some cases, the microfluidic channels at the common junction may have substantially the same hydrophobicity. In one set of embodiments, a device may include a common junction of six or more channels, where a first fluid flows through one channel, a second fluid flows through two channels, and a third or carrying fluid flows through two more channels, such that a double emulsion of a first droplet of the first fluid, contained in a second droplet of the second fluid, contained by the carrying fluid, flows away from the common junction through a sixth channel. | 2013-02-21 |
| 20130046031 | Process and Plant for Substitute Natural Gas - A methanation section for producing substitute natural gas (SNG) by reacting a fresh syngas, the methanation section comprising adiabatic reactors connected in series, with heat removal and reacted gas-recirculation, wherein the fresh syngas is fed in parallel to said adiabatic reactors. In a preferred embodiment the reacted gas is recirculated to the first reactor and further dilution of the fresh gas at the inlet of the first and second reactor is achieved by steam addition. | 2013-02-21 |
| 20130046032 | INTEGRATED PROCESS FOR PRODUCING ETHANOL FROM METHANOL - Processes and systems for forming ethanol from methanol. The process involves carbonylating the methanol to form acetic acid and hydrogenating the acetic acid to form ethanol. In a first aspect, at least some hydrogen for the hydrogenating step is derived from a tail gas stream formed in the carbonylation step. In a second aspect, at least some carbon monoxide for the carbonylation step is derived from a vapor stream in the hydrogenation system. In a third aspect, a syngas stream is separated to form a hydrogen stream and a carbon monoxide stream, and the hydrogen stream is methanated to remove residual carbon monoxide prior to being introduced into the hydrogenation system. | 2013-02-21 |
| 20130046033 | Process for the Production of Light Olefins from Synthesis Gas - A new process for light-olefins production is disclosed. The process comprises the step of contacting syngas with a iron-based catalyst at a temperature in the range from 250° C. to 350° C. and at a pressure in the range from 10 bar to 40 bar. By so doing a production of light olefins with a selectivity of at least 80% is obtained. | 2013-02-21 |
| 20130046034 | CONTROL OF THE MELT FLOW RATE OF POLYOLEFIN MIXTURES RECOVERED FROM POST-CONSUMER DURABLE GOODS - A process for creating polyolefin blends from waste streams with controlled rheological properties can include processing a waste stream to make a mixture comprising a mixture comprising polypropylene and polyethylene and compounding the mixture with one or more peroxides or nitroxides to produce a polyolefin blend. For example, a process can include: determining the required melt flow rate of the end product; determining the ratio of polyethylene to polypropylene to achieve the required melt flow rate; effecting a separation of polypropylene from polyethylene to achieve the desired composition; determining the amount of peroxide or peroxide concentrate required to increase the melt flow rate to the required level; melt compounding the mixture; evaluating the melt flow rate of the product; and adjusting the composition of polyethyelene and polypropylene or the amount of peroxide added if necessary to achieve the required melt flow rate. | 2013-02-21 |
| 20130046035 | STABLE FOAMED CEMENT SLURRY COMPOSITIONS AND METHODS FOR MAKING AND USING SAME - A foamed cement composition is disclosed for utilization in performing a variety of well cementing operations, and to methods for making and using same. The foamed cement composition basically includes a cement, water sufficient to form a pumpable slurry, a gas sufficient to foam the slurry, a foaming agent and optionally a foam stabilizing agent. | 2013-02-21 |
| 20130046036 | THERMOPLASTIC POLYURETHANES WITH EXCEPTIONAL FIRE RESISTANCE - Thermoplastic polyurethanes (TPUs) formulations including phosphonate oligomers, phosphonate co-oligomers, phosphonate polymers, or phosphonate containing copolymers which exhibit an excellent combination of properties including optical transparency and melt flow without significant reduction in other important physical or mechanical properties and exceptional fire resistance are described herein. | 2013-02-21 |
| 20130046037 | PROCESS FOR PRODUCING RIGID POLYURETHANE FOAMS - The invention relates to particle-comprising polyurethane foams, wherein the particles are incorporated predominantly in the cell walls. | 2013-02-21 |
| 20130046038 | COMPOSITIONS FOR COMPOUNDING FOAMABLE, FLUROPOLYMER PELLETS FOR USE IN MELT PROCESSING CELLULAR OR FOAMED FLUOROPOLYMER APPLICATIONS - The disclosure provides a composition as well as a set of compositions and method for producing cellular or foamed or blown fluoropolymers such as perfluoropolymers and other thermoplastics articles allowing for the creation of a lower cost communications cable, conductor separator, conductor support-separator, jacketing, tape, wire insulation and in some cases a conduit tube as individual components or combined configurations that exhibit improved electrical, flammability and optical properties. Specifically, the foamable or blown fluoropolymer such as a perfluoropolymer cellular insulation composition comprises; talc and the selected fluoropolymer such as perfluoropolymers. Compounded pellets or products resulting in cellular or foamable products using these pellets has also been realized by providing the melt combination in the pellets of only talc and a perfluoropolymer. | 2013-02-21 |
| 20130046039 | PROCESS FOR PREPARING THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDED PRODUCT - The application provides a process for preparing a thermoplastic elastomer composition (F) for injection molding, comprising dynamically heat-treating a thermoplastic elastomer composition (D), which comprises 95 to 5 parts by weight of an ethylene/α-olefin-based copolymer rubber (a), 5 to 95 parts by weight of a propylene/α-olefin random copolymer (b-1) (total of the components (a) and (b-1): 100 parts by weight), and 0 to 200 parts by weight of a softener (c), in the presence of an organic peroxide, wherein a crystallization nucleating agent (e) for olefin-based plastics is added in an amount of 0.01 to 5 parts by weight based on 100 parts by weight of the total of the components (a) and (b-1) before or after the dynamic heat treatment. | 2013-02-21 |
| 20130046040 | POLYETHYLENE POWDERS AND POROUS ARTICLES PRODUCED THEREFROM - A polyethylene powder has a molecular weight in the range of about 300,000 g/mol to about 2,000,000 g/mol as determined by ASTM-D 4020, an average particle size, D | 2013-02-21 |
| 20130046041 | Method for Producing Thin Films and the Application Thereof - A method for producing thin films, particularly for coating surfaces includes a) adding surface-active substances to flowable compositions comprising nanoscale inorganic particulate solids having polymerizable and/or polycondensable organic surface groups; b) forming one or more thin films stabilized by the accumulation of the surface-active substances at the interface(s), the forming of one or more thin films taking place through the generation of bubbles, foam, through the formation of minimal surfaces and/or through the wetting of surfaces; and c) solidifying the films by polymerization and/or polycondensation. | 2013-02-21 |
| 20130046042 | SEQUENTIALLY CROSS-LINKED POLYETHYLENE - A method of producing an improved polyethylene, especially an ultra-high molecular weight polyethylene utilizes a sequential irradiation and annealing process to form a highly cross-linked polyethylene material. The use of sequential irradiation followed by sequential annealing after each irradiation allows each dose of irradiation in the series of doses to be relatively low while achieving a total dose which is sufficiently high to cross-link the material. The process may either be applied to a preformed material such as a rod or bar or sheet made from polyethylene resin or may be applied to a finished polyethylene part. | 2013-02-21 |
| 20130046043 | Silicone Hydrogels and Methods of Manufacture - Embodiments of silicone hydrogels, ophthalmic lenses made therefrom, and methods of making the same are described. Fully hydrated silicone hydrogels have relatively high water content and oxygen permeability, along with relatively low modulus of elasticity. Embodiments of the silicone hydrogels in substantially dehydrated condition are adapted to lathe cutting at or above room temperature. Variations of the silicone hydrogels include silicon-containing monomers in an amount greater than 25% by weight, a hydrophilic substituted N-vinyl acetamide monomer in an amount greater than 30% by weight, and a hydrophilic non-acetamide monomer in an amount resulting in a hydrophilic substituted N-vinyl acetamide monomer to hydrophilic non-acetamide monomer weight to weight ratio of greater than 2.1 to 1. | 2013-02-21 |
| 20130046044 | Biodegradable Polymers and Methods for the Preparation Thereof - The present invention relates to biodegradable polymers, and especially polyacrylic and/or polyaspartic acid based biodegradable polymers. Further, the present invention relates to methods for the preparation of the present biodegradable polymers and the use thereof as, for example, protective layer or packaging material. Specifically, the present invention relates to methods for preparing a biodegradable polymer comprising: a) preparing an acidic mixture of polyacrylic and/or polyaspartic acid, sodium ions, one or more oligosaccharides, or derivatives thereof, and water, wherein the resulting mixture has a pH equal to or lower than 5; b) maintaining the temperature of said acidic mixture in a range of from 80° C. to 130° C. until an homogeneous suspension is obtained; and c) adding polyvinyl alcohol (PVA) and one or more polycarboxylic acids, or derivatives thereof, to the mixture of step (b) while maintaining the temperature in a range of from 80° C. to 130° C. until the biodegradable polymer is formed. | 2013-02-21 |
| 20130046045 | SIZING COMPOSITION FOR FIBERS, SIZED FIBERS AND METHOD OF SIZING FIBERS - Disclosed are aqueous size compositions for inorganic fibers which is based on a specific polymeric film former composition comprising
| 2013-02-21 |
| 20130046046 | POLY(ARYLENE ETHER) COMPOSITION, METHOD, AND ARTICLE - A composition includes specific amounts of a virgin poly(arylene ether) resin and a rubber-modified polystyrene that is preferably derived from post-consumer recycling. The composition includes about 0.2 to about 1.5 weight percent of polymerized acrylonitrile residue that can originate as a contaminant in the recycled rubber-modified polystyrene. The composition avoids the need for compatibilizing agents required by related compositions. | 2013-02-21 |
| 20130046047 | SAPONIFIED POLYMER COMPOSITION, POLYMER-TYPE ANTISTATIC AGENT, THERMOPLASTIC STYRENE-BASED RESIN COMPOSITION, FORMED BODIES, AND PROCESS FOR PRODUCTION THEREOF - Disclosed is a saponified polymer-containing composition containing a saponified polymer (A), which is obtained by alkaline saponification of an ethylene-unsaturated carboxylic acid random copolymer, and a dimer acid (B). | 2013-02-21 |
| 20130046048 | Use of a BTEX-Free Solvent to Prepare Stimulation and Oilfield Production Additives - Preparing a demulsifier, an oil soluble imidazoline corrosion inhibitor, an alkylphenolic resin, an alkylphenolic resin oxyalkylate, a paraffin inhibitor, a defoamer, an oil soluble scavenger, an oil soluble cleaner, a wetting agent, a surfactant, a foamer, and combinations thereof, in a non-limiting embodiment, in the absence of a BTEX solvent would be more beneficial to the environment than the same products prepared with BTEX solvent(s). The method may include adding an organic solvent to a mixture to form the aforementioned material(s). The organic solvent may be or include propylene glycol methyl ether acetate (PGMEA currently marketed as DOWANOL PMA™), dipropylene glycol methyl ether acetate (currently marketed as DOWANOL DPMA™), diisobutyl ketone (DIBK), methyl isobutylketone (MIBK), and mixtures thereof. | 2013-02-21 |
| 20130046049 | METHOD FOR PRODUCING THERMOPLASTIC ELASTOMER COMPOSITION - Disclosed is a method for producing a thermoplastic elastomer composition, the method comprising subjecting components (A), (B), (C), and (D) to dynamic thermal treatment in a melt-kneading apparatus, wherein the component (A) is an ethylene-α-olefin based copolymer rubber, the component (B) is a polyolefin resin, the component (C) is a liquid in which an alkylphenol resin has been dispersed and/or dissolved in a mineral oil, and the component (D) is a metal halide. | 2013-02-21 |
| 20130046050 | HYBRID PARTICLES MADE OF POLYMERS AND NANOPARTICLES - Subject of the invention is a hybrid particle comprising at least two vinyl polymers (vinyl polymers A and B), wherein vinyl polymer A comprises colloidal SiO | 2013-02-21 |
| 20130046051 | STRUCTURAL PROFILE MEMBERS FOR PRODUCING HOUSEHOLD UTENSILS, AND METHOD FOR PRODUCING SAID STRUCTURAL PROFILE MEMBERS - These structural profile members, such as handles, supports, frames and legs for ironing boards, indoor and outdoor clothes drying racks, etc., are obtained from recycled plastic materials. | 2013-02-21 |
| 20130046052 | Polymer Synthesis - A method of preparing a block copolymer of Formula (B) wherein P | 2013-02-21 |
| 20130046053 | VEHICLE MEMBER AND MANUFACTURING METHOD THEREFOR - Disclosed is a vehicle member that includes a molded body and a protective film disposed on a surface of the molded body and formed by curing of an active energy ray-curing composition. The active energy ray-curing composition contains an active energy ray-curing prepolymer (A) obtainable by a reaction of an acrylic-based prepolymer having a hydroxyl group and an acrylic monomer (a | 2013-02-21 |
| 20130046054 | HIGH REFRACTIVE INDEX COMPOSITION - A high refractive index composition comprising a reaction product of one or more first organic compounds capable of undergoing polymerization and one or more second compounds with high refractive index, and the method of making and using the composition. | 2013-02-21 |
| 20130046055 | PROCESS FOR PRODUCING AN AQUEOUS BINDER SYSTEM - The invention provides aqueous binder systems comprising at least one polymeric carboxylic acid, at least one saccharide compound and at least one alkanolamine having at least two hydroxyl groups. | 2013-02-21 |
| 20130046056 | CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS - The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, | 2013-02-21 |
| 20130046057 | POLYIMIDE MEMBRANES AND THEIR PREPARATION - Disclosed are (1) a method of preparing a polyimide membrane, including cross-linking polyimides via thermal labile side chains and decomposition of the thermal labile side chains; and (2) polyimide membranes thus prepared. | 2013-02-21 |
| 20130046058 | FLUORINE RESIN MOLDED ARTICLE AND PRODUCTION OF SAME - [Object] To provide a fluororesin molded article having a lowered concentration, of eluted fluorine ions subsequent to molding, and to provide a method for producing a fluororesin molded, article, a fluororesin molded article, and a fluororesin composition whereby the concentration of eluted fluorine ions is lowered. | 2013-02-21 |
| 20130046059 | USE OF POLYORGANOSILOXANES IN THE PROCESSING AND VULCANISATION OF RUBBER - The invention relates to the use of polyorganosiloxanes having 3 or more siloxane units, which have one or more organic fractions R | 2013-02-21 |
| 20130046060 | MATERIAL FOR GOLF BALL AND GOLF BALL - The present invention provides a material for a golf ball which increases the spin rate in wet conditions and allows a golf ball to stop well on approach shots, and a golf ball produced using the material for a golf ball. The present invention relates to a material for a golf ball including an acrylic elastomer, and having shear loss moduli G1″ (Pa) and G2″ (Pa) which satisfy the following inequality (1): | 2013-02-21 |
| 20130046061 | ETHYLENE-BASED POLYMER COMPOSITION - An ethylene-based polymer composition has been discovered and is characterized by a Comonomer Distribution Constant greater than about 45. The new ethylene-based polymer compositions are useful for making many articles, especially including films. The polymers are made using a metal complex of a polyvalent aryloxyether. | 2013-02-21 |
| 20130046062 | METHOD FOR REACTING - Provided is a method for efficiently and homogeneously reacting an ETFE having a functional group and a compound having a reactive functional group which can react with the functional group. A method for reacting an ethylene/tetrafluoroethylene copolymer having a functional group, which comprises reacting, in the presence of a solvent which can dissolve the ethylene/tetrafluoroethylene copolymer having a functional group, the ethylene/tetrafluoroethylene copolymer having a functional group and a compound (A) having a reactive functional group which can react with the functional group, in a dissolved state. | 2013-02-21 |
| 20130046063 | Irritation Mitigating Polymers and Uses Therefor - A method for increasing the efficacy of hydrophobically modified (meth)acrylic based polymers to increase the critical micelle concentration of a surfactant composition by attenuating the degree of neutralization (DN) of the polymer is disclosed. | 2013-02-21 |
| 20130046064 | USE OF SURFACE-TREATED CARBON BLACKS IN AN ELASTOMER TO REDUCE COMPOUND HYSTERESIS AND TIRE ROLLING RESISTANCE AND IMPROVE WET TRACTION - A composition of a surface-treated-carbon-black and a functionalized polymer with functionalization along the polymer chain is disclosed, wherein the polymer represents a solution SBR including, but not limited to blends of the SBR (PBR4003) with BR, NR and EPDM, and the SBR polymer functionalization comprises polar, oxygen-containing functional groups, such that the compound exhibits reduced hysteresis and rolling resistance, improved wet traction with excellent abrasion resistance as would be used in passenger, truck and racing tires. | 2013-02-21 |
| 20130046065 | POLYCYCLOPENTADIENE COMPOUNDS - Embodiments of the present disclosure include polycyclopentadiene compounds represented by Formula (I): in which each X is either a hydrogen or a cyano group (N≡C—), n has an average value from zero to 20; each m independently has a value of zero to 3; p has a value of zero to 20; each R is independently a halogen, a nitrile group, a nitro group, an alkyl group, an alkoxy group, an alkenyl group, or an alkenyloxy group, where the alkyl group, the alkoxy group, the alkenyl group, and the alkenyloxy group each independently contain 1 to 6 carbon atoms; and each Q is independently hydrogen or an alkyl group containing 1 to 6 carbon atoms. Embodiments of the present disclosure also include a curable composition that includes the polycyclopentadiene compound(s) of Formula (I) and a curing amount of a resin or a catalyst amount of a catalyst and/or a cure accelerating amount of an accelerating agent. | 2013-02-21 |
| 20130046066 | METHOD OF PREPARING A POLYMER AND COMPOSITIONS THEREFOR - The invention provides a method of making a polymer in the presence of a catalyst composition having an empirical formula M(glycerol) | 2013-02-21 |
| 20130046067 | POLYCYCLOPENTADIENE COMPOUNDS - The present disclosure provides for polycyclopentadiene compounds that useful as an epoxide resin and/or as an adduct for a curable composition. | 2013-02-21 |
| 20130046068 | METHOD FOR PREPARING SUPPORTED METALLOCENE CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME - The present invention relates to a method for preparing a supported metallocene catalyst, and a method for preparing polyolefin using the same, in which the supported metallocene catalyst prepared from the simple process according to the method for preparing the supported metallocene catalyst of the present invention can apply to the polymerization of the polyolefin that is polymerized at low pressure or high pressure; the molecular weight distribution of polyolefin prepared can be easily controlled; and there are effects such that its catalyst activity is significantly higher than that of the existed supported metallocene catalyst, and the molecular weight distribution can be easily controlled. | 2013-02-21 |
| 20130046069 | Method and apparatus for producing a film web from thermoplastic material and film produced thereby - The invention relates to a method and an apparatus for producing a film web made of thermoplastic material in which the thermoplastic material is extruded in at least one layer as plastic melt from a wide-slit nozzle in an extrusion direction and subsequently led away over at least roller, wherein tensile forces are exerted in the extrusion direction and transversely to the extrusion direction in order to stretch the film web longitudinally and transversely, wherein during application of the tensile forces in and transversely to the extrusion direction the film web has a temperature at least corresponding to the melting temperature of the same. | 2013-02-21 |
| 20130046070 | POLYMERIZATION PROCESS - The present invention relates to a process for the continuous transition between two different and compatible polymerisation catalysts. | 2013-02-21 |
| 20130046071 | Cellulose-Based Masterbatch with Networked Structure, Application Thereof and Method for Preparing the Same - Disclosed herein is a thermoplastic cellulosic composition for preparing a cellulose-based masterbatch and/or a cellulose-based fiber with a networked structure. In one example, the thermoplastic cellulosic composition includes an esterified cellulose present in a range of about 80 wt % to about 95 wt %, polyethylene glycol present in a range of about 4.5 wt % to about 12 wt %, a tri-functional cross-linking agent present in a range of about 0.01 wt % to about 3 wt %, an initiator present in a range of about 0.01 wt % to about 0.15 wt %, and a dispersing agent present in a range of about 0.01 wt % to about 5 wt %. | 2013-02-21 |
| 20130046072 | AROMATIC MONOMERS DERIVING FROM GLYCEROL UNITS, PROCESS FOR THEIR PREPARATION AND USE THEREOF FOR THE PREPARATION OF WATER-SOLUBLE CONJUGATED POLYMERS - Monomers having formula (I) and process for their synthesis which comprises the etherification reaction of a halogen-derivative (Z═Cl, Br, I) having formula (III) with the hydroxyl group of the glycerol derivative (IV), according to the following scheme:(Formula III, IV & I) (III) (IV) (I) | 2013-02-21 |
| 20130046073 | METHOD FOR PRODUCING POLYMER COMPOUND - The problem to be solved of the present invention is to provide a method for producing a polymer compound having an increased molecular weight through a short-time polymerization process. Means for solving the problem is a method for producing a polymer compound having a repeating unit represented by formula (2), which method comprising a step of polymerizing a first aromatic compound having at least two first functional groups each containing a boron atom with a second aromatic compound having at least two second functional groups which are capable of reacting with the first functional group, in the presence of an organic solvent, a palladium complex, a base and a compound represented by formula (1): | 2013-02-21 |
| 20130046074 | Polyamide Resin - This is to provide a polyamide resin which can sufficiently ensure all of a relative viscosity ηr (high degree of polymerization), moldable temperature range estimated from a temperature difference (Td−Tm), heat resistance estimated from a melting point Tm, melt moldability estimated from a temperature difference (Tm−Tc), and low water absorbability as compared with the conventional polyoxamide resin. | 2013-02-21 |
| 20130046075 | PROCESS FOR GAMMA-BUTYROLACTONE PRODUCTION - A double-walled plastic jar for cosmetic materials, having an inner compartment to hold the cosmetic, and an annular outer side wall defining the exterior of the jar. The inner compartment carries the lip that seals with a screw cap, and also carries an external skirt, which latter has the screw threads for engagement by the cap. In addition, a weight is disposed in a-concealed manner in the base of the jar, between the walls, to give the jar a heft feel, characteristic of glass or thick plastic walls. | 2013-02-21 |
| 20130046076 | Crystal Structure of Amino Terminal Portion of Influenza Virus Polymerase PA Subunit and Use thereof - Present invention disclosed three-dimensional crystal structure of N-terminus polypeptide of influenza virus polymerase subunit (PA_N). PA_N is residues 1˜50 to 150˜300 of influenza virus polymerase subunit PA. In three-dimensional structure, at least 40% of atoms showed same atomic coordinates, compared to that listed in Table. In other words, in three-dimensional structure of influenza virus polymerase subunit PA_N, 40% of atomic coordinates on carbon skeleton of residues of influenza virus polymerase subunit PA_N, showed less than or equal to 1.7 Å of average variance, compared to the atomic coordinates listed in Table1. Present invention also disclosed the expression, purification, crystallization methods, and three-dimensional crystal structure of 256 residues in the N-terminus of influenza virus polymerase subunit PA, and applications of the crystal structure on drug screening and designing. | 2013-02-21 |
| 20130046077 | DOLASTATIN 15 DERIVATIVES - Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, | 2013-02-21 |
| 20130046078 | ANTI-FGFR3 ANTIBODIES AND METHODS USING SAME - The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies. | 2013-02-21 |
| 20130046079 | MOUSE LAMBDA LIGHT CHAIN LOCUS - The present invention provides in a first aspect a mouse in which the λ (lambda) light chain locus has been functionally silenced. In one embodiment, the mouse λ light chain locus was functional silenced by deletion of acne segments coding for the λ light chain locus. In a further aspect, a mouse containing functionally silenced λ and κ (kappa) L chain loci was produced. The invention is useful for the production of antibodies, for example heterologous antibodies, including heavy chain only antibodies. | 2013-02-21 |
| 20130046080 | METHOD TO IMPROE THE SORBENT EFFICIENCY OF PROTEIN A CHROMATOGRAPHY USING SWITCHING COLUMN WITH CONTINUOUS FEEDING - The present invention relates to a method to improve the sorbent efficiency of protein A chromatography using switching column with continuous feeding. In the chromatography method of the present invention, the increased usage efficiency of the absorbent (resin), the decreased processing time, the decreased operation cycle of column compared to that of single batch-type column, and the reduced amount of used resin are achieved and thus, the target protein can be purified at a high efficiency and a low cost. | 2013-02-21 |
