08th week of 2020 patent applcation highlights part 19 |
Patent application number | Title | Published |
20200055747 | WASTE WATER TREATMENT SYSTEM WITH BUFFERING DEVICE AND WASTE WATER TREATMENT METHOD THEREFOR - Disclosed is a waste water treatment system with a buffering device, the system comprising a waste water pretreatment device, an evaporator, a circulating crystallizer, a crystal filtration device and a water removal device which communicate with each other in sequence, and further comprising a primary buffering device and a secondary buffering device, wherein one end of the primary buffering device is in bi-directional communication with the circulating crystallizer, and the other end thereof is connected to the evaporator; and the secondary buffering device is in bi-directional communication with the circulating crystallizer. Further disclosed is a waste water treatment method for a waste water treatment system with a buffering device. | 2020-02-20 |
20200055748 | IRON-BASED DESALINATION - Systems, devices, and techniques described herein relate to iron-based desalination of water. In some cases, an inflow of water including chlorine and sodium can be received. A plurality of iron nanoparticles may capture the chlorine and the sodium. The iron nanoparticles may at least partially include Zero Valent Iron (ZVI). An outflow of the water may be emitted. The chlorine and the sodium may be omitted from the outflow. | 2020-02-20 |
20200055749 | WATER SYSTEM FLOOR INTERFACE WITH ULTRAVIOLET LIGHT TREATMENT - An ultraviolet (UV) light disinfection system for treating water prior to its delivery to a water usage device. One or more UV light emitting diodes (LEDs) are positioned within a water system floor interface in order to expose water flowing through the system to germicidal light treatment. | 2020-02-20 |
20200055750 | SYSTEM AND METHOD OF DEIONIZATION OF WATER - A method of treating water in a water treatment system after a replacement of an ion exchange bed includes introducing water to be treated into the ion exchange bed of the water treatment system to produce treated water, calculating a current exchange daily average flow rate of water through the water treatment system, calculating a cumulative daily average flow rate of water through the water treatment system, and determining an estimated number of days remaining to exhaustion of the ion exchange bed based on the current exchange daily average flow rate and the cumulative daily average flow rate. | 2020-02-20 |
20200055751 | METHOD OF MEMBRANE-COUPLED ELECTROCHEMICAL ADVANCED OXIDATION AND ITS APPLICATION DEVICE FOR WATER PURIFICATION AND WATER PURIFICATION SYSTEM USING OF THE SAME - The present invention relates to an electrochemical advanced oxidation process combined with a membrane in which electrode reactions and membrane filtration occur simultaneously, a water treatment device based on the electrochemical advanced oxidation process, and a water treatment system using the water treatment device. The electrochemical advanced oxidation process includes: providing a membrane electro-oxidation tank where electrodes are combined with a membrane; accommodating wastewater containing pollutants in the membrane electro-oxidation tank; and supplying power to the electrodes to decompose the pollutants and simultaneously separating particles through the membrane (water treatment). The electrodes are arranged downstream of the membrane. Gases released from the electrodes induce a vertical flow of the fluid to improve the contact efficiency between a reactive solution and the electrodes and remove the pollutants attached to the surface of the membrane. According to the present invention, a mechanism of decomposing pollutants using the electrodes and a mechanism of separating particles through the membrane take place simultaneously, enabling effective removal of the pollutants. The electrodes are arranged downstream of the membrane. With this arrangement, gases are produced from the electrodes to improve the electrolysis reactivity and the filtration efficiency of the membrane. | 2020-02-20 |
20200055752 | ELECTROLYZED WATER PRODUCTION DEVICE - An electrolyzed water production device produces electrolyzed water including hypochlorous acid by electrolyzing water including chloride ions, and includes an electrolytic cell through which water passes, and an electrode provided inside the electrolytic cell; and the electrode includes a catalyst layer including iridium oxide, tantalum oxide, and rhodium oxide, in which a proportion of a number of rhodium atoms included in the rhodium oxide to a sum of a number of iridium atoms included in the iridium oxide, a number of tantalum atoms included in the tantalum oxide, and the number of rhodium atoms is not less than 31% and not more than 60%. | 2020-02-20 |
20200055753 | WATER TREATMENT SYSTEM - A system is provided for treating and distributing water. The system includes a first container and an input conduit that supplies water (e.g., purified, unpurified, etc.) to the first container. The system also has a treatment delivery system that delivers a mineral composition into the first container. Further, the system uses a controller to selectively deliver the mineral composition in to the first container so that the mineral composition mixes with, and dissolves in the water delivered to the first container. This produces treated water having a programmed profile, which can be distributed to a destination (e.g., a coffee shop) via an output conduit. | 2020-02-20 |
20200055754 | WATER TREATMENT APPARATUS, WATER TREATMENT SYSTEM AND WATER TREATMENT METHOD - A water treatment apparatus includes: a reaction vessel that contains water to be treated, including an upper part from which the water to be treated is introduced and a lower part from which the water to be treated is discharged, to form a downward flow; an ozone supply unit that supplies ozonized gas into the reaction vessel from the lower part to form an upward flow of the ozonized gas containing ozone gas and oxygen; and an electrolysis electrode pair disposed on the upper part of the reaction vessel, the pair that produces hydrogen peroxide from the water to be treated and the oxygen gas contained in the ozonized gas by electrolysis. | 2020-02-20 |
20200055755 | SYSTEM AND METHOD FOR WATER DISINFECTION - The efficiency of water disinfection can be significantly increased by supplying the ozone in combination with oxygen to an inlet of a cavitation pump. The ozone and the oxygen are turned into ultra-fine bubbles via cavitation action within the pump, facilitating the dissolution of the oxygen and ozone within the water. The water mixed with the oxygen and the ozone is subsequently supplied to a line atomizer, where the dissolution of the ozone within the mixture is completed. The combined use of the cavitation pump and the line atomizer can lead to a substantially complete dissolution of the supplied ozone within water that needs to be disinfected, allowing to easily achieve the concentration of ozone necessary for water disinfection. Due to this efficiency, the system and method described are highly scalable and suitable for water purification at water purification plants of various sizes. | 2020-02-20 |
20200055756 | EDUCTOR-BASED MEMBRANE BIOREACTOR - A process for treating domestic wastewater may include directing wastewater into a tank containing a membrane filter and mixed liquor. The process may include recirculating wastewater and mixed liquor from a top end of the tank into a bottom end of the tank via a recirculation conduit. The process may include introducing a flow of wastewater and mixed liquor from the recirculation conduit into an aeration device and drawing ambient air into the aeration device using the flow of wastewater and mixed liquor from the recirculation conduit. The process may also include drawing wastewater and mixed liquor proximately surrounding the aeration device into the aeration device using the flow of wastewater and mixed liquor from the recirculation conduit. The process may include aerating a mixture of wastewater and mixed liquor with the ambient air below the membrane filter. | 2020-02-20 |
20200055757 | SYSTEM AND METHOD FOR CONTROLLED GAS-DISPERSION-RETURN-SLUDGE-BASED WASTEWATER TREATMENT - Control over the wastewater purification can be achieved through controlling delivery of gas-dispersion return sludge solely to an aerobic reaction vessel. The gas-dispersion return sludge is created using pure oxygen or oxygen containing trace amounts of ozone as a reactive gas, which is blended with return sludge to create a mixture of gas and liquid, which is pressurized with an atomizer pump, and then at a pressure of not more than approximately 5.5 MPa, the mixture is passed through an atomizer which uses cavitation or ultrasound at a frequency of less than 12,000 KHz to instantly render the reactive gas in the mixture to an ultra-fine bubble state. A portion of the gas is placed into a dissolved state, reaching a state of supersaturation with a high DO value of 20-40 mg/l, and causing the remaining ultra-fine bubbles to create an ultra-fine bubble condition. | 2020-02-20 |
20200055758 | Method for Relieving Corrosive Environment of Boiling Water Reactor, Nuclear Power Plant, and Method for Injecting Noble Metal Which is Carried Out in Nuclear Power Plant - The present disclosure provides a method for relieving a corrosive environment of a boiling water reactor, the method including a step of injecting hydrogen and a noble metal compound into water to be replenished into the reactor pressure vessel during a period of a generating operation of a boiling water nuclear power plant including the reactor pressure vessel. In the method, the hydrogen is injected into water to be supplied into the reactor pressure vessel, and the noble metal compound is injected into water in a line of the boiling water nuclear power plant in which a concentration of oxygen or hydrogen peroxide is stoichiometrically higher than the concentration of hydrogen at which hydrogen undergoes a chemical reaction to turn to water. Thus, when a noble metal is injected into a boiling water reactor, the noble metal can be restrained from adhering onto a pipe for an injection and other pipes, and thereby can increase the amount of the noble metal to be injected into a cooling water in a reactor pressure vessel. | 2020-02-20 |
20200055759 | Method for Disinfecting and Cleaning Liquid Media and Method for Separating Solid and Liquid Constituents of a Solid-Liquid Mixture and Apparatus for Implementing the Method - The invention relates to a method for cleaning and/or disinfecting liquid and/or aqueous media, comprising the following method steps: cavitation treatment of the medium, in particular by means of jet cavitation, at a negative pressure <1 bar, preferably 0.3 to 0.7 bar; subsequent treatment of the medium in a hydrodynamic reactor having a a rotating magnetic field and magnetic and/or magnetisable elements, in particular having ferromagnetic needles or a rotating cutting mechanism at a negative pressure <1 bar, preferably 0.3 to 0.7 bar; subsequent separation, in particular sedimentation of the treated medium by means of sludge separation at a negative pressure of <1 bar, preferably 0.3 to 0.7 bar. The invention further relates to an apparatus having the following features: a cavitator formed in particular as a jet cavitator, which is equipped with a negative pressure generator, a hydrodynamic reactor having a rotating magnetic field and magnetic and/or magnetisable elements, in particular having ferromagnetic needles and/or a rotating cutting mechanism, a unit for separation, in particular for sedimentation, preferably combined with a sludge separation apparatus. | 2020-02-20 |
20200055760 | Beverage dispenser and method therefore for suppression of germ formation - The present invention discloses a beverage dispenser, including: an inlet connected to a water source; an outlet for dispensing the water to a user vessel; at least one filter element having an input and an output for filtered water; a pump for pumping water to the input of the filter element; a flow sensor connected between the inlet and the outlet, wherein the flow sensor determines the actual flow rate of the water; at least one water preparation element connected between the output for outputting filtered water and the outlet and adapted to prepare the water for drinking by a human, wherein the water preparation element comprises a water preparation rate input by which the water preparation rate of the water preparation element can be controlled; and a controller connected to the water preparation rate input of the water preparation element and the flow sensor, wherein the controller controls the water preparation rate of the water preparation element by a signal to the water preparation rate input such that the water preparation rate is proportional to the actual flow rate. | 2020-02-20 |
20200055761 | Beverage dispenser and method therefore for suppression of germ formation - The present invention discloses a beverage dispenser, including: an inlet connected to a water source; an outlet for dispensing the water to a user vessel; at least one filter element having an input and an output for filtered water; a pump for pumping water to the input of the filter element; a flow sensor connected between the inlet and the outlet, wherein the flow sensor determines the actual flow rate of the water; at least one water preparation element connected between the output for outputting filtered water and the outlet and adapted to prepare the water for drinking by a human, wherein the water preparation element comprises a water preparation rate input by which the water preparation rate of the water preparation element can be controlled; and a controller connected to the water preparation rate input of the water preparation element and the flow sensor, wherein the controller controls the water preparation rate of the water preparation element by a signal to the water preparation rate input such that the water preparation rate is proportional to the actual flow rate. | 2020-02-20 |
20200055762 | METHOD FOR CONVERSION OF WET BIOMASS TO ENERGY - Disclosed herein is a method of converting waste, such as wet biomass, to a clean product and energy, including heat, and/or power. The disclosed method combines hydrothermal processing, also known as anaerobic hydrothermal carbonization, followed by wet air oxidation, adding sufficient oxygen to ensure rapid and complete destruction of organics. | 2020-02-20 |
20200055763 | APPARATUS AND METHOD TO CONTROL GOB WEIGHT, LENGTH AND/OR SHAPE - An improved system and method for forming falling hot glass gobs which will be molded into glass containers in an Individual Section (IS) machine is disclosed which controls the weight, length, and shape of such glass gobs as they are produced. The system includes a gob feeder apparatus and a gob shearing mechanism a controller using models being used to correlate the effect of a number of feeder control settings on gob weight, length, and, shape. The controller is configured to adjust various feeder control settings based on a prioritized order of the feeder control settings such that gobs having different physical characteristics for different ones of the individual sections can be produced during a single machine cycle. By implementing the models, a closed loop system has been developed to set up controls to achieve the desired gob forming for each individual section and cavity. | 2020-02-20 |
20200055764 | GLASS-CERAMIC ARTICLES WITH IMPROVED STRESS PROFILES - Glass-ceramic articles are manufactured by an ion exchange process that results in glass-based articles having improved stress profiles. A knee may be located at a depth of 3 microns or deeper. A compressive stress at a surface may be 200 MPa or more and at a knee may be 20 MPa or more. A non-sodium oxide may have a non-zero concentration that varies from the first surface to a depth and a depth of compression (DOC) may be located at 0.10·t, or even at 0.17·t or deeper. A two-step ion exchange (DIOX) includes, for example, a potassium bath in a first treatment to form a spike in a spike region of the stress profile, followed by a second treatment which includes, for example, a potassium and sodium mixed bath to maintain the spike and form a tail region of the stress profile. The glass-ceramic articles may thereby avoid developing a vitreous surface layer, which facilitates repeatable and reliable measurement of waveguide modes and determination of compressive stress in the surface (CS) and depth of the spike. | 2020-02-20 |
20200055765 | DEVICE FOR PRESS-CUTTING GLASS, METHOD FOR PRESS-CUTTING GLASS, AND GLASS-CUTTING SYSTEM - Provided are a device for press-cutting glass, a method for press-cutting glass, and a glass-cutting system having the device for press-cutting glass. The device for press-cutting glass comprises a supporting member, having a first supporting portion and a second supporting portion for supporting a glass substrate, which are arranged in a spaced apart manner in a first direction; and a press-cutting member for press-cutting an edge of the glass substrate, which is positioned between the first supporting portion and the second supporting portion in the first direction. The device for press-cutting glass has advantages including high press-cutting efficiency, simple structure, low manufacturing cost, and easy assembling with other devices. | 2020-02-20 |
20200055766 | 3D LASER PERFORATION THERMAL SAGGING PROCESS - In some embodiments, a method of forming a glass article comprises perforating a glass substrate along a contour with a laser forming a plurality of perforations, such that the contour separates a first portion of the glass substrate from a second portion of the glass substrate. After perforating, thermal forming the glass substrate into a non-planar shape with a mold, and separating the first portion of the glass substrate from the second portion of the glass substrate. | 2020-02-20 |
20200055767 | GLASS FLAKES AND RESIN COMPOSITION - Glass flakes of the present invention have an average particle diameter of 0.1 to 15 μm and an average thickness of 0.1 to 2 μm. The glass flakes have a particle size distribution in which the particle diameter at 99% of the cumulative volume from the smaller particle diameter is 45 μm or less, and the maximum particle diameter of the glass flakes is 62 μm or less. | 2020-02-20 |
20200055768 | GLASSES HAVING IMPROVED TOUGHNESS AND SCRATCH RESISTANCE - A silicate glass that is tough and scratch resistant. The toughness is increased by minimizing the number of non-bridging oxygen atoms in the glass. In one embodiment, the silicate glass is an aluminoborosilicate glass in which −15 mol %≤(R | 2020-02-20 |
20200055769 | THERMALLY TEMPERED GLASS ELEMENT AND USE THEREOF - A thermally tempered glass element is provided made of glass with two opposite faces that are under compressive stress of at least 40 MPa. The glass has a working point at which the glass has a viscosity of 10 | 2020-02-20 |
20200055770 | GLASS FLAKES AND RESIN COMPOSITION - The glass flakes of the present invention include first glass flake substrates and second glass flake substrates and satisfy at least either of the following conditions (A) and (B): (A) an average thickness of the first glass flake substrates is 0.05 to 2 μm, an average thickness of the second glass flake substrates is 2 to 20 μm, and the average thickness of the second glass flake substrates is 3 or more times greater than the average thickness of the first glass flake substrates; and (B) a thickness D1 representing a modal value of a thickness distribution (on a number basis) of the first glass flake substrate is 0.03 to 2.5 μm, a thickness D2 representing a modal value of a thickness distribution (on a number basis) of the second glass flake substrates is 1.5 to 25 μm, and the thickness D2 is 2 or more times greater than the thickness D1. | 2020-02-20 |
20200055771 | FILM-ATTACHED GLASS SUBSTRATE, ARTICLE, AND METHOD FOR PRODUCING FILM-ATTACHED GLASS SUBSTRATE - The present invention relates to a film-attached glass substrate, characterized by: being provided with a glass substrate having two primary surfaces each having a compressive stress layer, and a film containing 1 at % or more of K disposed on one of the primary surfaces of the glass substrate; and the ratio of the difference in the amount of K in the compressive stress layer between the primary surfaces, the ratio being represented by formula (1), being −0.027 to 0.027. Formula (1): Ratio of difference in amount of K of compressive stress layer between primary surfaces=(amount of K in first primary surface−amount of K in second primary surface)/[(amount of K in first primary surface+amount of K in second primary surface)/2] | 2020-02-20 |
20200055772 | METHOD FOR MANUFACTURING COLOR COATED PLATE GLASS - A method of producing a colored film-attached glass sheet includes a step of obtaining a colored film-forming coating solution by mixing the following components: (a) a reaction product obtained by reacting an amino group-containing silane compound with at least one boron compound selected from the group consisting of H | 2020-02-20 |
20200055773 | CHEMICALLY STRENGTHENED GLASS - The purpose of the present invention is to provide a chemically strengthened glass in which reduction in glass surface strength is effectively suppressed even without performing a polishing treatment after a prolonged chemical strengthening treatment has been conducted at a high temperature. The present invention relates to a chemically strengthened glass having a specific glass composition, wherein: the surface roughness (Ra) is a specific value or greater; the compressive stress layer depth of a surface layer is a specific value or greater; by setting the hydrogen concentration in the glass surface layer to be within a specific range, the surface strength of the glass is dramatically improved even without performing an etching treatment using hydrofluoric acid or polishing the glass surface after a prolonged chemical strengthening treatment has been conducted at a high temperature. | 2020-02-20 |
20200055774 | CARBONATION-ACTIVATED CLINKER BINDER FROM INCINERATION RESIDUES - A process for synthesis of a waste-derived CO | 2020-02-20 |
20200055775 | EARLY STRENGTH ENHANCEMENT OF CEMENTS - A method of making a cement composition, comprising grinding a cement clinker and a strength-enhancing agent, thereby producing a hydraulic cementitious powder, wherein the strength-enhancing agent is present in the hydraulic cementitious powder in an amount of from 0.001% to 0.09% based on dry weight of the hydraulic cementitious powder. The strength-enhancing agent is a compound represented by the following structural formula (I). The definitions of variables R | 2020-02-20 |
20200055776 | Concrete Element Reinforced with Improved Oxidation Protection - A concrete element with improved fire resistance having a textile reinforcement, such as carbon fibers. The concrete covers the textile reinforcement around 10 to 25 mm, the concrete being made from binding agents based on geopolymers or calcium-aluminate cements or Portland cement or blast furnace cement combined with an increased concentration of more than 2 kg/m | 2020-02-20 |
20200055777 | DRY CONSTRUCTION COMPOSITION WHICH CAN BE WET-SPRAYED BY MEANS OF SCREW PUMP AND COMPRISING A BINDER AND A BIO-BASED FILLER - PREPARATION AND USES OF SUCH A COMPOSITION - A dry construction composition that is easily wet-sprayed by a screw pump to form an insulating and mechanically resistant material after hardening comprises: at least one binder that includes at least one primary binder comprising lime and/or at least one source of alumina and/or at least one source of calcium sulfate, at least one water retention agent, and preferably at least one surfactant; and at least one plant-based bio-based filler based on sunflower stalk and/or corn stalk and/or rape stalk, having a Bulk Density (BD) in kg/m | 2020-02-20 |
20200055778 | SYNTHETIC MARBLE ITEMS AND METHODS OF MAKING THEM - In an aspect, there is provided a shaped item comprising a synthetic marble-like material. In an aspect, there is provided a method for producing a shaped item comprising a synthetic marble-like material. | 2020-02-20 |
20200055779 | ZIRCONIA ARTICLE WITH HIGH ALUMINA CONTENT, PROCESS OF PRODUCTION AND USE THEREOF - The invention relates to a porous zirconia article in particular for use in the dental or orthodontic field, the porous zirconia article comprising ZrO | 2020-02-20 |
20200055780 | SINTERED MATERIAL AND METHOD OF PRODUCING SAME - A sintered material includes a first phase and a second phase, wherein the first phase is composed of cubic boron nitride particles, and the following relational expressions are satisfied when more than or equal to two cubic boron nitride particles adjacent to and in direct contact with each other among the cubic boron nitride particles are defined as a contact body, Di represents a length of an entire perimeter of the contact body, n represents the number of contact locations at which the cubic boron nitride particles are in direct contact with each other, d | 2020-02-20 |
20200055781 | ELABORATION OF AN ADVANCED CERAMIC MADE OF RECYCLED INDUSTRIAL STEEL WASTE - A ceramic and a method of forming a ceramic including milling steel slag exhibiting a diameter of 5 mm of less to form powder, sieving the powder to retain the powder having a particle size in the range of 20 to 400 removing free iron from the powder with a magnet, heat treating the powder at a temperature in the range of 700° C. to 1200° C. for a time period in the range of 1 hour to 10 hours and oxidizing retained iron in the powder, compacting the powder at a compression pressure in the range of 20 MPa to 300 MPA, and sintering the powder at a temperature in the range of 700° C. to 1400° C. for a time period in the range of 0.5 hours to 4 hours to provide a ceramic. | 2020-02-20 |
20200055782 | RAPID SINTERING SYSTEM AND RAPID SINTERING METHOD - A rapid sintering system and rapid sintering method, the rapid sintering system comprising: a furnace body ( | 2020-02-20 |
20200055783 | PRODUCTION METHOD OF CALCIUM CARBONATE POROUS SINTERED BODY - Provided is a production method that can easily produce a calcium carbonate porous sintered body. The production method includes the steps of: preparing a dispersion liquid containing calcium carbonate and a gelling agent; adding a foaming agent to the dispersion liquid, followed by stirring until foamy to make a foam; turning the foam into a gel; and sintering the gelled foam to produce a calcium carbonate porous sintered body. | 2020-02-20 |
20200055784 | ADDITIVE FOR HYDRAULICALLY SETTING COMPOSITIONS - The present invention relates to an additive for hydraulically setting compositions comprising a colloidally disperse preparation comprising at least one salt of a polyvalent metal cation with at least one organic phosphonate and/or phosphate compound as anion and at least one polymeric dispersant comprising anionic and/or anionogenic groups and polyether side chains. The additive is especially suitable as slump retainer and for improving early strength. | 2020-02-20 |
20200055785 | ADMIXTURE FOR HYDRAULIC COMPOSITION - An admixture for a hydraulic composition includes a polycondensation product P containing a copolymer prepared by polycondensation of a monomer mixture containing compounds A to C of the following Formulae (A) to (C); and a polycarboxylic acid-based polymer Q including a structural unit having an amino and an imino group, and/or a structural unit having an amino, imino, and amido group: | 2020-02-20 |
20200055786 | CONCRETE MANUFACTURING METHOD USING NITROGEN DISSOLVED WATER AND METHOD FOR MANUFACTURING REINFORCED CONCRETE STRUCTURE - Provided are a concrete manufacturing method capable of preventing neutralization of concrete and oxidation of a reinforcing rod in reinforced concrete, and a method for manufacturing a reinforced concrete structure using the same. The concrete manufacturing method uses nitrogen dissolved water and is characterized by including: a step of generating nitrogen dissolved water by injecting nitrogen gas into water to replace oxygen and carbon dioxide dissolved in the water with nitrogen; and a step of generating a ready-mixed concrete by kneading the nitrogen dissolved water, cement, an aggregate, and an admixture. The method for manufacturing a reinforced concrete structure is characterized by forming a reinforced concrete structure using a ready-mixed concrete manufactured by a concrete manufacturing method using nitrogen dissolved water. | 2020-02-20 |
20200055787 | STABILIZED REFRACTORY COMPOSITIONS - A refractory composition including refractory aggregate, one or more matrix components, and silicate-coated set accelerator particles. The silicate-coated set accelerator particles can include one more of silicate-coated calcium hydroxide, magnesium hydroxide, calcium chloride, calcium carbonate, magnesium carbonate and calcium sulfate. Suitable silicate coatings include sodium silicate, potassium silicate, lithium silicate and mixtures thereof. A method of recovering an aged refractory composition, a settable composition and a method of manufacturing silicate-coated calcium hydroxide particles are also provided. | 2020-02-20 |
20200055788 | Chemical and topological surface modification to enhance coating adhesion and compatibility - A process of coating a substrate containing silicon with an environmental barrier coating, comprising altering a surface of the substrate and applying an environmental barrier layer to the surface of the substrate. | 2020-02-20 |
20200055789 | Protective Coating for Ceramic Matrix Composites - An article has a substrate and a layer atop the substrate. The layer has: a matrix comprising at least one of hafnium silicate (HfSiO | 2020-02-20 |
20200055790 | Surface-Coated Cutting Tool - A surface-coated cutting tool including a substrate including a rake face and a flank face and a coating which covers a surface of the substrate is provided. The substrate is made of a cBN sintered material or a ceramic sintered material. The coating includes an alternating layer. The alternating layer is made by alternately stacking a first layer and a second layer different in composition from the first layer. The first layer contains Al, Cr, and N. The second layer contains Ti, Al, and N. A ratio T | 2020-02-20 |
20200055791 | METHOD FOR PRODUCING FERTILIZER PARTICLES COMPRISING ALTERNATIVE BORON SOURCES - The present disclosure concerns a method for producing fertilizer particles comprising an alternative source of boron. It is found that certain colemanite and ulexite powders can be supplied to a fertilizer melt shortly before granulation essentially without dissolving into the melt. Accordingly, the fertilizer particles produced from the melt may contain negligible amounts or non-detectable levels of sodium borates or boric acid. Furthermore, the fertilizer particles can be homogeneous which is desirable for boron supplying fertilizers. It is also found that the fertilizer particles can supply boron to plants at a rate comparable to borax pentahydrate. | 2020-02-20 |
20200055792 | FREEZE CONCENTRATION FOR URINE-BASED FERTILIZER PRODUCTION - A system for generating a concentrated product from a feedstock includes a feedstock chamber to which the feedstock is provided, a heat exchanger assembly in thermal communication with the feedstock chamber, the heat exchanger assembly being configured to freeze the feedstock in the feedstock chamber, an output flow arrangement configured to carry liquid from the feedstock chamber as the feedstock thaws, the output flow arrangement comprising a flow controller, a sensor disposed along the output flow arrangement or the heat exchanger assembly, the sensor being configured to measure a characteristic of the liquid, the characteristic being indicative of a solute concentration level of the liquid or the heat exchanger assembly, and a processor responsive to the characteristic and configured to control the flow controller to, based on the solute concentration level, direct the liquid passing through the output flow arrangement to define a plurality of products at different concentration levels, the plurality of products comprising the concentrated product. | 2020-02-20 |
20200055793 | SOIL ENHANCEMENT - Systems and methods are disclosed to provide a plant nutrient by selecting a microbial solution with predetermined characteristics for agriculture use; iteratively and selectively breeding generations of microbes for microbial strain selection with predetermined microbial gene profiles to arrive at a predetermined microbial solution, wherein multiple single microbial series are separately cultivated and followed with cross cultivation among the microbial series in a specific sequence; and mixing by-products produced by the crossly cultivated microbial series with a fertilizer, a mineral or both. | 2020-02-20 |
20200055794 | Reactive Inorganic Coatings for Agricultural Fertilizers - The invention relates to a coated granular fertilizer, preferably wherein granules are sulfate-based or phosphate-based. When sulfate based granules, as in ammonium sulfate, the coating substance is an inorganic salt of alkaline earth elements, preferably calcium, such that when applied to the surface of fertilizers, forms calcium sulfate, preferably a calcium sulfate-dihydrate, as a protective coating. For a reactive coating of a thiosulfate, free sulfuric acid present on the granule reacts to provide an elemental sulfur coating. For ammonium phosphate-based granules, coatings may comprise compounds of Ca | 2020-02-20 |
20200055795 | BINDERS FOR THE GRANULATION OF FERTILIZERS - According to some demonstrative embodiments, there is provided herein a fertilizer granule including a fertilizer dust and one or more binders wherein said granule comprises a single strength of at least 2.5 kg/gran and a single strength after humidity chamber 24 hours, 79% RH of at least 0.5 kg/granule. | 2020-02-20 |
20200055796 | ETHYLENE-TO-LIQUIDS SYSTEMS AND METHODS - Integrated systems are provided for the production of higher hydrocarbon compositions, for example liquid hydrocarbon compositions, from methane using an oxidative coupling of methane system to convert methane to ethylene, followed by conversion of ethylene to selectable higher hydrocarbon products. Integrated systems and processes are provided that process methane through to these higher hydrocarbon products. | 2020-02-20 |
20200055797 | OLIGOMERIZATION OF OLEFINS DERIVED FROM OXYGENATES - Systems and methods are provided for conversion of oxygenate feeds to lubricant and/or distillate boiling range compounds with desirable properties by first selectively converting oxygenates to light olefins and then converting the light olefins to distillate and lubricant boiling range compounds with beneficial properties. The distillate boiling range products can have an unexpectedly high cetane, while the lubricant boiling range products can have an unexpectedly high viscosity index. The ability to form the distillate boiling range products and lubricant boiling range products is facilitated by using a Ni-enhanced oligomerization catalyst. | 2020-02-20 |
20200055798 | METHOD FOR PRODUCING ALPHA-OLEFIN OLIGOMER - A method for producing an α-olefin oligomer, the method including subjecting α-olefin to oligomerization reaction to produce an α-olefin oligomer mixture, carrying out distillation separation of α-olefin oligomer having less than n carbon atoms in the mixture to obtain a distillation residue containing α-olefin oligomer having n or more carbon atoms, and then carrying out a step of removing high molecular weight molecules from the distillation residue. | 2020-02-20 |
20200055799 | Linear Alpha Olefin Process Using Temperature Control in Oligomerization Reactor - The present disclosure provides assemblies for producing linear alpha olefins and methods for producing linear alpha olefins. In at least one embodiment, a method for producing a linear alpha olefin includes providing an olefin, a catalyst, and a process solvent to a first tubular reactor; obtaining an effluent from the first tubular reactor; and transferring the effluent to a second tubular reactor. In at least one embodiment, an assembly for producing linear alpha olefins includes a first tubular reactor having a first end and a second end; an effluent line having a first end and a second end, the first end coupled with the second end of the first tubular reactor; and a second tubular reactor having a first end and a second end, the first end coupled with the second end of the effluent line. | 2020-02-20 |
20200055800 | Linear Alpha Olefin Process Using Solvent Flash Drum for Olefin Separation - The present disclosure provides assemblies for producing linear alpha olefins and methods for producing linear alpha olefins. In at least one embodiment, a method for producing a linear alpha olefin includes providing an olefin, a catalyst, and a process solvent to a reactor under oligomerization conditions; obtaining an effluent produced in the reactor; and transferring the effluent to a solvent-containing portion of a flash drum via a first effluent line coupled with the flash drum. In at least one embodiment, an assembly for producing linear alpha olefins includes a configuration to provide olefin, catalyst and process solvent coupled with a reactor; a flash drum; a first effluent line coupled with the reactor at a first end and coupled with the flash drum at a second end; and a second effluent line coupled with the flash drum at a first end and coupled with the first effluent line at a second end. | 2020-02-20 |
20200055801 | PROCESSES AND SYSTEMS FOR SEPARATING CARBON DIOXIDE IN THE PRODUCTION OF ALKANES - A method for separating CO | 2020-02-20 |
20200055802 | SYSTEMS AND METHODS FOR ISOPRENE PURIFICATION - Methods for the selective hydrogenation of acetylenic compounds in a product stream that includes isoprene. A method of selectively hydrogenating an acetylenic hydrocarbon in the presence of isoprene may include obtaining a hydrocarbon mixture comprising an acetylenic hydrocarbon, isoprene, and butadiene or cyclopentadiene, or both. If cyclopentadiene is present, the hydrocarbon mixture may comprise greater than 2 wt. % cyclopentadiene. The method may further include contacting the hydrocarbon mixture and hydrogen (H | 2020-02-20 |
20200055803 | COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME AND METHOD FOR PREPARING SAME - The present specification relates to a compound of Chemical Formula 1, a coating composition including the compound of Chemical Formula 1, an organic light emitting device using the same, and a method for manufacturing the same. | 2020-02-20 |
20200055804 | PROCESS FOR REDUCING 3,3,3-TRIFLUOROPROPYNE IN 2,3,3,3-TETRAFLUOROPROPENE - The invention relates to a process for reducing the concentration of a fluorinated alkyne impurity, such as 3,3,3-trifluoropropyne (TFPY), in 2,3,3,3-tetrafluoropropene (HFO-1234yf) which comprises contacting such a mixture with a caustic material, such as sodium hydroxide (NaOH), under conditions effective to reduce the concentration of the fluorinated alkyne impurity, including in some practices reducing the concentration by at least about 50%. | 2020-02-20 |
20200055805 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS - A series of benzosuberene analogues demonstrate effective inhibition of tubulin polymerization, cytotoxicity against human cancer cell lines, and vascular disruption in tumors. | 2020-02-20 |
20200055806 | PROCESS FOR THE PREPARATION OF ALPH-FUNCTIONALIZED KETONES - The present invention refers to a process for the preparation of an α-functionalized ketone, an α-functionalized ketone obtained by said process, a photopolymerizable composition comprising the α-functionalized ketone and at least one photopolymerizable unsaturated compound, a method of preparing an article, an article obtained by said method, as well as the use of the α-functionalized ketone or the photopolymerizable composition as photoinitiator. | 2020-02-20 |
20200055807 | METHOD FOR ALCOHOLYSIS OF AMIDE - Provided is a method for the alcoholysis of an amide. The method comprises subjecting an amide-containing compound to alcoholysis under alkaline conditions using an epoxy compound as an accelerant of alcoholysis. | 2020-02-20 |
20200055808 | COMPOSITION FOR USE IN DETECTING AN ALLERGY TO CLAVULANIC ACID - The authors of the present invention describe compounds derived from or structures related to clavulanic acid and the medical uses thereof. The invention also relates to a composition, a dosage form, a kit or device, and the uses of same. | 2020-02-20 |
20200055809 | PROCESS FOR CONVERTING S-ENANTIOMER TO ITS RACEMIC FORM - The present invention relates to a novel process for converting the unwanted S enantiomer form to its useful raceme with respect to a 4-aminoindane derivative and to novel intermediates of said process. | 2020-02-20 |
20200055810 | Novel Compositions For Preventing And/Or Treating Degenerative Disorders Of The Central Nervous System And/Or Lysosomal Storage Disorders - The present invention provides novel compounds as well as compositions and methods using the same for preventing and/or treating degenerative disorders of the central nervous system and/or lysosomal storage disorders. In particular, the present invention provides methods for preventing and/or treating Parkinson's disease, Alzheimer's disease and/or Gaucher's disease. | 2020-02-20 |
20200055811 | METHOD OF SYNTHESIZING DICLOFENAC SODIUM - The invention relates to the chemical synthesis of pharmaceutical API, and specifically to a method of synthesizing diclofenac sodium, which is a kind of nonsteroidal anti-inflammatory drug for relieving pain. The method includes: nitrating phenylacetate to prepare o-nitrophenylacetate (2); hydrogenating o-nitrophenylacetate (2) to prepare o-aminophenylacetate (3); amidating an amino group of o-aminophenylacetate (3) to obtain 2-(2-benzoylaminophenyl) acetate (4); 2-(2-benzoylaminophenyl) acetate (4) reacting with thionyl chloride to prepare a chloroimine intermediate, and then condensing the intermediate of chloroimine with 2,6-dichlorophenol using an inorganic base to prepare (E)-methyl-2-(2-((2,6-dichlorophenoxy)(phenyl)methyleneamino) phenyl ester (5); subjecting (E)-methyl-2-(2-((2,6-dichlorophenoxy)(phenyl)methyleneamino) phenyl ester (5) to Chapman rearrangement to afford methyl 2-(2-(N-(2,6-dichlorophenyl)benzoylamino)phenyl) ester (6); and hydrolyzing methyl 2-(2-(N-(2,6-dichlorophenyl)benzoylamino)phenyl) ester (6) to provide the target compound as of diclofenac sodium API. The overall yield is up to 67% based on methyl phenylacetate. | 2020-02-20 |
20200055812 | AMMONIUM CARBOXYLATE COMPOUND, CRYSTALLINE FORM, AMORPHOUS FORM AND PREPARATION METHOD THEREOF - The present disclosure belongs to the field of chemical synthesis, and in particular relates to an ammonium carboxylate compound, a crystalline form and an amorphous form, and a preparation method thereof. The present disclosure prepares the compound and the crystalline form I and its single crystal, amorphous form and crystalline form II thereof. The compound, the crystalline forms, the single crystal and the amorphous form can stably exist and exhibit good solid forms, suitable for medicine-making. Furthermore, these products possess high purity and less single impurity. Moreover, the preparation methods of the present disclosure are easy to implement due to the simple processes with mild reaction conditions, and could produce products of high yield and high purity without complex purification steps. Furthermore, the preparation methods may facilitate safety, environmental protection, and industrial production. | 2020-02-20 |
20200055813 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS - The present invention is directed to a compound represented by Structural Formula (A): | 2020-02-20 |
20200055814 | ANTI-FIBROTIC COMPOUNDS - Provided herein are anti-fibrotic compounds, in particular those of Formula (I), that inhibit the TGF-beta signaling pathway. Also provided are pharmaceutical compositions comprising the anti-fibrotic compounds, and methods of treating diseases or conditions associated with fibrosis, inflammation, and benign or malignant neoplastic diseases in a subject by administering a compound KIN or composition described herein. (Formula (I)) | 2020-02-20 |
20200055815 | TUNABLE NITRIC OXIDE-RELEASING MACROMOLECULES HAVING MULTIPLE NITRIC OXIDE DONOR STRUCTURES - Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein. | 2020-02-20 |
20200055816 | PREPARATION OF COMPOUNDS FROM LEVULINIC ACID - The present invention provides a method of making carboxylic acids from levulinic acid, such as succinic acid and 3-hydroxypropanoic acid, by reacting levulinic acid with an oxidant such as hydrogen peroxide under acidic or basic conditions. | 2020-02-20 |
20200055817 | SPIRO-COMPOUNDS AS SIP MODULATORS - The invention relates to heterocyclic compounds of formula (I) as SIP modulators, pharmaceutical compositions comprising such compounds, and uses thereof in the treatment or alleviation of diseases or disorders mediated by an SIP receptor. | 2020-02-20 |
20200055818 | PSYCHOTROPIC AGENTS AND USES THEREOF - Novel amisulpride derivatives and pharmaceutical compositions thereof are disclosed. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may have better membrane permeability compared to amisulpride. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for antagonizing dopamine and/or serotonin (e.g., 5-HT2a) and/or α2 receptor in a subject, either individually or in combination with other CNS active agents. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for treating one or more conditions responsive to modulation of dopamine and/or serotonin (e.g., 5-HT2a) and/or α2 receptor in a subject, either individually or in combination with other CNS active agents. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for treating one or more disorders associated with an abnormality in levels of dopamine and/or serotonin in the brain, either individually or in combination with other CNS active agents. | 2020-02-20 |
20200055819 | NICOTINYL ALCOHOL ETHER DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USES THEREOF - The present invention discloses a nicotinyl alcohol ether derivative, a preparation method therefor, and a pharmaceutical composition and uses thereof. Specifically, the invention relates to nicotinyl alcohol ether derivatives represented by formula (I), a pharmaceutically-acceptable salt thereof, a stereoisomer thereof, a preparation method therefor, a pharmaceutical composition containing the one or more compounds, and uses of the compounds in treating diseases related to PD-1/PD-L1 signal channels, such as cancers, infectious diseases and autoimmune diseases. | 2020-02-20 |
20200055820 | ADDUCTS OF PYRROLE DERIVATIVES TO CARBON ALLOTROPES - Adducts are described formed between pyrrole derivatives of formula (I) an carbon allotropes in which the carbon is sp | 2020-02-20 |
20200055821 | METHOD FOR MANUFACTURING DIASTEREOMER OF CITRIC ACID DERIVATIVE - By using ion exchange column chromatography or calcium carbonate to an aqueous solution containing a compound A represented by the following formula and citric acid, citric acid in the aqueous solution is removed and a crystalline compound A is obtained by being thereafter subjected to several steps. Further a high-purity noncrystalline compound A is obtained by using calcium carbonate, sulfuric acid, an organic solvent and the like to the aqueous solution containing the compound A and citric acid to remove citric acid and the crystalline compound A in the solution. The configuration of the crystalline compound A is an SS isomer in the RS notation system. The configuration of the noncrystalline compound A is an SR isomer. | 2020-02-20 |
20200055822 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES - The present application relates to triarylamine compounds of a defined formula. The present application further relates to processes for preparing the compounds, to the use of the compounds in electronic devices, and to electronic devices comprising the compounds. | 2020-02-20 |
20200055823 | QUINOLONE COMPOUND - The present invention provides a compound represented by the formula (I) | 2020-02-20 |
20200055824 | WDR5-MLL1 INHIBITORS AND MODULATORS - Benzamides and picolinamides that are meta-substituted with imino-, guanidino-, or heterocycle-containing groups disrupt the WDR5-MLL1 protein-protein interaction, and have use in pharmaceutical compositions and in treating proliferative disorders and conditions in a subject, such as cancer. | 2020-02-20 |
20200055825 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR - The present disclosure relates to bifunctional compounds, which find utility to degrade (and inhibit) Androgen Receptor. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds Androgen Receptor such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of Androgen Receptor. | 2020-02-20 |
20200055826 | PYRIMIDINYLOXY BENZO-FUSED COMPOUNDS AS HERBICIDES - Disclosed are compounds of Formula (1), including all stereoisomers, N-oxides, and salts thereof (Formula (1)) wherein K, Z, R | 2020-02-20 |
20200055827 | 5HT1F RECEPTOR AGONISTS AND MITOCHONDRIAL BIOGENESIS - Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, promote mitochondrial biogenesis and are useful for the treatment of, for example, acute kidney injury and chronic kidney disease. | 2020-02-20 |
20200055828 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS - Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically, quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions containing the inhibitor compounds and methods of treatment of cancer comprising administering an effective amount of the Braf inhibitor compound are described. | 2020-02-20 |
20200055829 | 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION - Benzoylamides of the general formula (I) are described as herbicides. | 2020-02-20 |
20200055830 | 3-ALKYL BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS - The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with an HDAC, e.g., HDAC6, having a Formula I: | 2020-02-20 |
20200055831 | HETEROCYCLIC P2X7 ANTAGONISTS - Disclosed are compounds of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions containing them, and to a process for the preparation of the compounds: | 2020-02-20 |
20200055832 | PRODUCTION OF 2,5-FURANDICARBOXYLIC ACID - The invention is directed to the to the electrochemical preparation of 2,5- furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (HMF) by electrochemical oxidation, comprising a first oxidation step of oxidizing HMF to 5-hydroxymethyl-2-furan-carboxylic acid (HMFCA) in an electrochemical cell, subsequently a first isolation step of isolating HMFCA, followed by a second oxidation step of HMFCA to FDCA. | 2020-02-20 |
20200055833 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES - The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositions and ophthalmic devices comprising such compounds. | 2020-02-20 |
20200055834 | PROCESS FOR THE PREPARATION OF UNSATURATED CARBOXYLIC ACIDS BY CARBONYLATION OF ALLYL ALCOHOLS AND THEIR ACYLATION PRODUCTS - The present invention relates to a process for carbonylating allyl alcohols at low temperature, low pressure and/or low catalyst loading. In an alternative embodiment, an acylation product of the allyl alcohol is used for the carbonylation. The present invention likewise relates to the preparation of conversion products of these carbonylation products and specifically of (−)-ambrox. | 2020-02-20 |
20200055835 | USE OF TRICYCLIC SESQUITERPENE LACTONES IN THE TREATMENT OF OBESITY AND RELATED DISEASES AND NON-THERAPEUTIC TREATABLE CONDITIONS - A compound of the formula I, wherein the symbols are as defined in the remaining specification, or a mixture of two or more compounds of the formula I, for use as active ingredient in the therapeutic—including prophylactic—treatment of a warm-blooded animal for the regulation of body weight (preferred) and/or fat loss (preferred) and/or for the management of obesity and/or for improving the total cholesterol HDL/LDL ratio; where the compound(s) of the formula I may be present in free form, in the form of a pharmaceutically and/or nutraceutically acceptable salt, in the form of tautomers, in the form of esters and/or in the form of solvates, as well as related invention embodiments. | 2020-02-20 |
20200055836 | METHODS AND COMPOSITIONS RELATING TO GENOTOXIN COLIBACTIN - The technology described herein is directed to compounds which are substrates for ClbP, acting as fluorescent probes for ClbP activity. Further provided herein are methods for measuring ClbP activity, screening for ClbP inhibitors, detecting colibactin, and/or diagnosing cancer, which utilize the substrate compounds. | 2020-02-20 |
20200055837 | METHODS OF MANUFACTURING OF NIRAPARIB - Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib. | 2020-02-20 |
20200055838 | O-AMINOHETEROARYL ALKYNYL-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF - An o-aminoheteroaryl alkynyl-containing compound has a structure represented by formula (I), and the compound of formula (I) has advantages of a high FGFR and RET double target inhibitory activity and a relatively low KDR activity, and the compound of formula (I) exhibits a strong inhibitory activity in a human lung cancer cell line NCI-H1581 and a gastric cancer cell line SNU16 as well as an RET-dependent sensitive cell line BaF3-CCDC6-Ret and a mutant thereof. Pharmacokinetic data shows that the o-aminoheteroaryl alkynyl-containing compound has druggability, and exhibits significant relevant inhibition of the growth of related tumors in a long-term animal model of drug efficacy and results in favorable animal condition at effective doses. | 2020-02-20 |
20200055839 | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION - Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS. | 2020-02-20 |
20200055840 | POTENT GAMMA-SECRETASE MODULATORS - Provided herein are compounds and methods for treating a disorder associated with aberrant Aβ peptide levels, including Alzheimer's disease. | 2020-02-20 |
20200055841 | METHODS OF TREATING INFLAMMATION OR NEUROPATHIC PAIN - Provided herein are methods of treating inflammation or neuropathic pain using an effective dose of a monoacylglycerol lipase inhibitor or a composition thereof. | 2020-02-20 |
20200055842 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF - The present invention covers substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular and renal diseases, as a sole agent or in combination with other active ingredients. | 2020-02-20 |
20200055843 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS - The present invention encompasses compounds of the formula (I) | 2020-02-20 |
20200055844 | 4-SULFONYLAMINOCARBONYLQUINOLINE DERIVATIVES FOR INCREASING CFTR ACTIVITY - The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity. | 2020-02-20 |
20200055845 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME - Provided herein are methods of using KRAS G12C inhibitors and compositions of the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers. | 2020-02-20 |
20200055846 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO - This document discloses molecules having the following formula (“Formula One”): | 2020-02-20 |