07th week of 2019 patent applcation highlights part 38 |
Patent application number | Title | Published |
20190049408 | ELECTROCHEMICAL MEASUREMENT USING PHENYLENEDIAMINE DERIVATIVE - The present invention addresses the problem of providing a means for making highly sensitive and stable measurements possible using electrochemical measurement methods. This problem is resolved by providing: a labeling substance represented by general formula (1) and used to label a substrate; a measurement substrate that is formed by being labeled using the labeling substance; a method of measuring using electrochemical measurement methods that use the measurement substrate; and a reagent kit that includes as components the labeling substance and/or the measurement substrate. | 2019-02-14 |
20190049409 | METHOD AND DEVICE FOR IDENTIFYING DEFECT OPENING PROFILE - A method for identifying a defect opening profile includes: acquiring a vertical component of a magnetic flux leakage signal of a defect; identifying right-angle features and corresponding right-angle position points of the defect from the vertical component; obtaining all possible right-angle types at each right-angle position point of the defect according to the corresponding right-angle feature of the vertical component; traversing all the possible right-angle types at each right-angle position point to determine respective optimal right-angle type at each right-angle position point; and drawing the defect opening profile according to the respective optimal right-angle type at each right-angle position point. | 2019-02-14 |
20190049410 | EDDY CURRENT INSPECTION PROBE - A number of embodiments of inventive eddy current probes for non-destructive inspection of electrically conductive tubes are described. These include a bearing-centered probe, a spring loaded wheel-centered probe, a multi-part probe for curved tube inspection having limited excursion ball joints connecting the probe parts, and a 3D printed probe including features that are incapable of being manufactured through conventional casting or machining processes. | 2019-02-14 |
20190049411 | METHODS AND DEVICES FOR INSPECTION OF PIPELINES - Systems and methods for inspection of pipelines are disclosed herein. In one embodiment, an electromagnetic acoustic transducer (EMAT) transceiver (TRX) for inspecting a pipe includes a multichannel EMAT transmitter (TX) having multiple collocated transmitter coils. The EMAT TX can generate forward-propagating ultrasound waves and backward-propagating ultrasound waves. The forward-propagating ultrasound waves have higher amplitude than the backward-propagating ultrasound waves. The EMAT TRX also includes a multichannel EMAT receiver (RX) having multiple receiver coils that can receive the ultrasound waves transmitted by the EMAT TX through the pipe. | 2019-02-14 |
20190049412 | FIBER OPTIC ACOUSTIC EMISSION SENSOR AND APPARATUS - A method of monitoring a structure for stresses or cracks. A single mode optical fiber is adhered to a structure. The single mode optical fiber includes a first optical cavity. The first optical cavity includes two fiber Bragg gratings with a distance therebetween. The first optical cavity includes a resonance. A frequency shift of the resonance of the first optical cavity is measured with a frequency discriminator. An acoustic emission from the structure is detected based on the frequency shift. | 2019-02-14 |
20190049413 | METHOD FOR DIAGNOSING PERFORMANCE DEGRADATION OF MACHINE ELEMENT, AND SYSTEM FOR SAME - A system for diagnosing performance degradation of a machine element includes an AE sensor that generates an AE waveform signal; a vibration sensor that generates an acceleration signal; a signal processing unit including an AE signal processing system that performs predetermined signal processing on the plurality of AE waveform signals, a vibration signal processing system that performs predetermined signal processing on the acceleration signal, and a switching parameter generating section that generates a predetermined numeric parameter to switch a measuring mode from the AE method to the vibration method; and controlling unit that selects a result of the processing in performed by the AE signal processing system at the initial stage and selects, after the numeric parameter successively turns from increasing to decreasing, a result of the processing by the vibration signal processing system. | 2019-02-14 |
20190049414 | METHOD FOR ANALYZING BY-PRODUCTS OF RNA IN VITRO TRANSCRIPTION - The present invention relates to the detection and analysis of by-products in a process of RNA in vitro transcription by HPLC. It further relates to the use of this method for the quality control of RNA produced by in vitro transcription or for identifying suitable RNA purification conditions. | 2019-02-14 |
20190049415 | SYSTEM AND METHOD FOR DESORBING AND DETECTING AN ANALYTE SORBED ON A SOLID PHASE MICROEXTRACTION DEVICE - Disclosed herein is a system for desorbing and detecting an analyte sorbed on a solid phase microextraction (SPME) device. The system includes a desorption chamber sized to accept the SPME device while defining a void volume of less than about 50 μL; a flow injector in fluid connection with the desorption chamber, the desorption chamber and the flow injector being fluidly connected by at least a flow-insulating fluid connector; a solvent source in fluid connection with the flow injector; and a fluid switch that: in a desorption position, allows the solvent to be sprayed from the flow injector while flow-insulating any desorption solution in the desorption chamber, and in an detecting position, turns off the solvent source while maintaining the fluid connection between the flow injector and the desorption chamber, transferring the desorption solution through the flow-insulating fluid connector to the flow injector as a substantially undiluted plug of liquid. | 2019-02-14 |
20190049416 | METHOD TO INCREASE THE CHROMATOGRAPHIC RESOLUTION OF OLEFIN-BASED POLYMERS WITH DIFFERENT MICROSTRUCTURES - A method increase of the Resolution Index (Rl) of a chromatogram generated from a polymer sample comprising at least two olefin-based polymers of different microstructures and/or at least two olefin-based polymer fractions of different microstructures. The method comprises separating the mixture on a low-porosity stationary phase and repeatedly cycling the sample-stationary phase through a series of cooling and heating stages with active eluent flow only during the cooling stages and during the last heating stage to elute the separated analytes off the column. | 2019-02-14 |
20190049417 | OVEN INSULATION ARRANGEMENT - An analytical device has an oven arrangement (1) with an oven (2), an insulation system, a ventilation system and a housing. The ventilation system has a first convection system that uses natural convection, arranged to keep the housing cool, as well as a second convection system that uses forced convection, arranged to reduce the temperature in the oven (2). In particular, the analytical device is a component of a Karl Fischer titration instrument. | 2019-02-14 |
20190049418 | METHODS FOR DETERMINING OXIDATION PERFORMANCE OF OXIDATION CATALYST DEVICES - A method for determining the hydrocarbon (HC) oxidation performance of an oxidation catalyst device (OC) includes communicating gas to the OC inlet over a time frame, measuring the NOx content of the OC outlet gas using a NOx sensor over the time frame, wherein the temperature of the OC increases over the time frame, and correlating an increased NOx measurement over the time frame to an increased OC HC oxidation performance. The NOx sensor can be operated in a low temperature mode during the time frame. The method can further comprise determining the temperature of the OC over the time frame and correlating the HC oxidation performance to the OC temperature, and/or correlating a maximum NOx concentration measured during the time frame to the OC temperature measured at the same time. HC slip through the OC can be identified when the measured NOx content of the OC outlet gas decreases. | 2019-02-14 |
20190049419 | Method and Apparatus for Applying Aggregating Sampling to Food Items - Certain aspects of the present disclosure relate to methods and apparatus for microbial sampling of foods. For example, a method may include providing at least one aggregating sampler at one or more sampling locations, and sampling a production lot of produce or other food items such as meat using the at least one aggregating sampler to create one or more samples that makes up a microbial sampling. Certain aspects of the present disclosure relate to methods and apparatus for microbial sampling of foods. For example, an apparatus, such as a microbial aggregating sampler, may include a covering having a microbial sampling material with a pocket formed in the covering to receive an appendage or a tool for handling of the covering. | 2019-02-14 |
20190049420 | INSPECTION SYSTEM AND INSPECTION APPARATUS - An inspection system includes a sealable container and a detection apparatus that detects, in accordance with an inspection operation, a substance emitted by a specimen. When the specimen and the detection apparatus are stored in the container and the inspection operation is performed, the detection apparatus stored in the container detects the substance emitted by the specimen stored in the container. | 2019-02-14 |
20190049421 | SYSTEMS AND METHODS FOR MULTIVARIATE ANALYISIS USING MULTI-SUBSYSTEM DATA - Systems and methods for analyzing an unknown sample are disclosed. The system includes at least one subsystem to obtain molecular information about the sample and at least one other subsystem to obtain elemental information about the sample. The system also includes a data collection component to collect and combine the information from the subsystems to create combined analytical information and a multivariate model that relates known attributes to information previously generated with at least two analytical systems that are the same types of systems as the at least two analytical subsystems. A prediction engine applies the multivariate model to the combined analytical information to produce predictions of attributes in the unknown sample. | 2019-02-14 |
20190049422 | SOIL MOISTURE DOWNSCALING USING TOPOGRAPHY, SOIL, AND VEGETATION DATA - Systems and methods are disclosed to downscale the resolution of a coarse-resolution soil moisture data. Coarse-resolution soil moisture data may include data cells that each represent a geographic region having at least one dimension greater than or equal to 1 km. A plurality of fine-resolution supplemental soil moisture data may be received that includes at least one of soil data, vegetation data, topography data, and climate data. The fine-resolution supplemental soil moisture data comprising data cells that each represent a geographic region having at least one dimension less than or equal to 100 meters. The coarse-resolution soil moisture data may be downscaled to fine-resolution soil moisture data using the plurality of fine-resolution supplemental soil moisture data, the fine-resolution soil moisture data comprising data cells that each represent a geographic region having at least one dimension less than 100 meters. | 2019-02-14 |
20190049423 | Portable Apparatus for Liquid Chemical Characterization - An apparatus or method determines a salinity or metal content a liquid sample by scanning the liquid sample using a PXRF spectrometer, receiving a PXRF spectra from the PXRF spectrometer, baseline correcting and smoothing the received PXRF spectra, extracting a Kα emission line of one or more elements from the baseline corrected and smoothed PXRF spectra using only one beam from the PXRF spectrometer, determining the salinity or the metal content of the liquid sample using the one or more processors and a predictive model that relates the Kα emission line of the one or more elements to the salinity or the metal content of the liquid sample, and providing the salinity or the metal content of the liquid sample to the one or more input/output interfaces. | 2019-02-14 |
20190049424 | DEVICE FOR ANALYSING THE SENSITIVITY TO THE FORMATION OF DEPOSIT IN A FUEL, IN PARTICULAR A FUEL USED IN AIRCRAFT - The present invention is a device for analyzing sensitivity to deposit formation in a fuel notably used in aircraft, comprising a tank ( | 2019-02-14 |
20190049425 | Oil Well Gauging System and Method of Using the Same - A method and apparatus includes devices for measuring the liquid rate, pressure, temperature and water cut from a production well, components and devices for diverting a liquid sample into a cylinder vessel, and components and devices for measuring parameters of the separated water phase of the liquid sample. The sample collection and analysis provides a means of significantly improving the accuracy of full-range water cut measurement by providing for improved calibration of a full range water cut meter. | 2019-02-14 |
20190049426 | CULTURING PATCH, CULTURING METHOD, CULTURE TEST METHOD, CULTURE TEST DEVICE, DRUG TEST METHOD, AND DRUG TEST DEVICE - The present disclosure relates to a culturing patch, culturing method, culture test method, culture test device, drug test method, and drug test device, and the culturing patch according to an aspect of the present disclosure includes component required for growth of an object to be cultured, and a mesh structural body provided in a mesh structure forming micro-cavities in which the component required for growth are contained that is configured to come into contact with a reaction region in which the object to be cultured is placed and provide some of the contained component required for growth to the reaction region. | 2019-02-14 |
20190049427 | PORTABLE DIAGNOSTIC MEASUREMENT DEVICE FOR DETERMINING ANALYTICAL PARAMETER OF BODY FLUID - Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device. | 2019-02-14 |
20190049428 | PLATELET AGGREGABILITY ANALYZING DEVICE, PLATELET AGGREGABILITY ANALYZING SYSTEM, PLATELET AGGREGABILITY ANALYZING PROGRAM, AND METHOD OF ANALYZING PLATELET AGGREGABILITY - There are provided a new device and a new method for measurement of platelet aggregability which can be used for monitoring in an anti-platelet therapy. | 2019-02-14 |
20190049429 | METHOD FOR OBSERVING DYNAMICS OF SWEAT GLANDS - A method for observing the dynamics of sweat glands and a method for evaluating a substance of interest, which are useful for development of a preparation for external application, such as a cosmetic. In each of the methods, an observation sample is used, which is prepared by staining all sweat glands, which are isolated alive, with a staining reagent, and then holding the all sweat glands on a support using at least one material selected from the group consisting of collagen, agarose, basement membrane matrix, poly-D-lysine and a membrane. | 2019-02-14 |
20190049430 | NOVEL OMA1 ACTIVITY ASSAY - The present disclosure relates to methods and compositions for detecting mitochondrial dysfunction. In particular, the disclosure relates to reporter molecules that are cleavable by the zinc metalloprotease Metalloendopeptidase OMA1 (OMA1). In each embodiment, the reporter molecules of the invention are particularly useful for drug discovery and detection of diseases associated with mitochondrial dysfunction | 2019-02-14 |
20190049431 | METHOD OF PREPARING CELLS EXHIBITING DRUG RESISTANCE, METHOD OF SCREENING ANTICANCER DRUGS, AND ANTICANCER DRUG SCREENING KIT - A method of producing drug resistant cells including contacting exosomes from a living organism exhibiting drug resistance with cells exhibiting no drug resistance such that drug resistant cells are formed, and culturing the drug resistant cells. | 2019-02-14 |
20190049432 | ANTI-CANCER DRUG ASSESSMENT METHOD - A method of assessing an anti-cancer drug including culturing a cell structure including cancer cells and stromal cells in a presence of at least one anti-cancer drug, and assessing an anti-cancer effect of the at least one anti-cancer drug based on a number of viable cancer cells in the cell structure after the culturing. | 2019-02-14 |
20190049433 | ELECTRODE CONFIGURATION SCHEME FOR ELECTROPHYSIOLOGICAL TESTING DEVICES - A device and system allows for simplified connection, disconnection, and mitigation of signal interference for electrophysiological testing. One or more electrophysiological electrodes are attached to the patient. These electrodes are connected to leads which are bundled based on region with a single connector associated with each bundle. The bundles are individually keyed and colored for ease of connection and disconnection. Leads within a bundle are organized through the use of a retainer. Electrode bundles are connected to a junction box within proximity to the patient. A single cable connects the junction box to an electrophysiological testing and monitoring interface. A system for visualizing lead bundle data, organizing individual electrode data by the lead bundles that they are associated, facilitates a workflow allowing for rapid and simple channel identification in association with specific electrode regions. | 2019-02-14 |
20190049434 | MULTI-STAGE, MULTIPLEXED TARGET ISOLATION AND PROCESSING FROM HETEROGENEOUS POPULATIONS - A system and method for isolating target substrates includes a microfluidic chip, comprising a plurality of processing units, each processing unit comprising: an inlet port, a plurality of first chambers connected to the inlet port by a fluid channel, the fluid channel comprising a plurality of valves, a plurality of second chambers, each of the second chambers connected to a respective first chamber by a fluid channel, each fluid channel including a controllable blocking valve, and a plurality of respective outlet ports, each outlet port in fluid communication with a respective one of said second chambers and each outlet port including a blocking valve. A magnet is adjacent the microfluidic chip and is movable relative to the microfluidic chip. A valve control is capable of actuating certain ones of the controllable blocking valves in response to a control signal. | 2019-02-14 |
20190049435 | METHODS AND REAGENTS FOR DETERMINATION AND TREATMENT OF ORGANOTROPIC METASTASIS - The present invention relates to methods and kits for prognosing, treating, and managing treatment of cancer in a subject. The methods involve selecting a subject having cancer and obtaining, from the selected subject, a sample containing exosomes or an S100 molecule containing sample. The exosomes or S100 molecule containing sample, respectively, are then contacted with one or more reagents suitable to detect higher or lower levels or the presence or absence of one or more integrins on said exosomes or higher or lower levels or the presence or absence of one or more S100 molecules in the S100 molecule containing sample. The cancer is then prognosed, treatment is administered, or treatment is managed. | 2019-02-14 |
20190049436 | MODULATION OF ASYMMETRIC PROLIFERATION - Provided herein are methods and compositions related to modulation of the rate of asymmetric proliferation of cancer cells. In some embodiments, the methods described herein relate to the treatment of cancer, at least in part, via the modulation of the rate of asymmetric proliferation of cancer cells. | 2019-02-14 |
20190049437 | IMPROVED METHODS FOR MONITORING IMMUNE STATUS OF A SUBJECT - The invention generally provides improved compositions and methods for monitoring immune status of a subject. In particular, the invention provides methods for detecting BCMA in subjects to reliably monitor immune status of the subject. | 2019-02-14 |
20190049438 | Exosome-Total-Isolation-Chip (ExoTIC) Device for Isolation of Exosome-Based Biomarkers - A device (“the ExoTIC device”) for the isolation of extracellular vesicles from an extracellular vesicle-containing sample in which the sample is flowed through a membrane in a flow chamber to capture and purify the extracellular vesicles on the membrane. The extracellular vesicles may be washed and collected and utilized in any one of a number of ways including, but not limited to, identifying biomarkers of a disease, identifying the presence of a biomarker in a patient to determine whether a patient has a disease, and therapeutically treating existing diseases by re-introducing the extracellular vesicles, potentially modified, back into a body. | 2019-02-14 |
20190049439 | Kit for a Determination Method for Calprotectin and the Use of Calprotectin as a Predictive Marker for Cardiovascular Disease - An assay kit for the use in a method for the detection of potential for CVD or propensity to CVD in a human or non-human animal subject. The method including assessing the concentration of calprotectin in a calprotectin-containing sample taken from the subject. | 2019-02-14 |
20190049440 | LABEL-FREE DETECTION OF RENAL CANCER - Natural and/or synthetic antibodies for specific proteins are adhered to nanoparticles. The nanoparticles are adhered to a substrate and the substrate is exposed to a sample that may contain the specific proteins. The substrates are then tested with surface enhanced Raman scattering techniques and/or localized surface plasmon resonance techniques to quantify the amount of the specific protein in the sample. | 2019-02-14 |
20190049441 | METHOD FOR DETERMINING KINETIC PROFILES IN DRUG DISCOVERY - The present invention relates to a reliable, robust and sensitive platform aimed to analyze the massive kinetic profile of new molecules against its main target and also against other potential targets. Thus, the present invention relates to a method for calculating the kinetic profile of a compound of interest against a target protein or polyprotein wherein it is not needed to predetermine the K | 2019-02-14 |
20190049442 | INTEGRATED DEVICE FOR ANALYTE TESTING, CONFIRMATION, AND DONOR IDENTITY VERIFICATION - An apparatus for testing a fluid sample including a sample receiving member having an opening for receiving a fluid sample, wherein the sample receiving member comprises a sample collection chamber; a fluid collector to collect the fluid sample and transfer the fluid sample into the sample receiving member, the fluid collector comprising a lancet and an absorbent material to absorb the fluid sample; and a test cartridge member in fluid communication with the sample collection chamber. | 2019-02-14 |
20190049443 | BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE THERAPY - Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are uses of inflammatory biomarkers for guiding treatment decisions. | 2019-02-14 |
20190049444 | Methods of Treating Cardiovascular Diseases and Predicting the Efficacy of Exercise Therapy - Methods of treating a subject having a cardiovascular disease, selecting a therapy for a subject having a cardiovascular disease, identifying a subject having a cardiovascular disease that will benefit or not benefit from exercise therapy, determining whether a subject having a cardiovascular disease should begin, continue, not begin, discontinue, or avoid exercise therapy, determining whether a subject having a cardiovascular disease should continue, discontinue, or avoid exercise therapy, reducing the risk of an adverse outcome (e.g., death) in a subject having a cardiovascular disease, and predicting the efficacy of exercise therapy in a subject having a cardiovascular disease. These methods include determining a level of soluble ST2 in a subject. | 2019-02-14 |
20190049445 | METHOD FOR IDENTIFYING BY MASS SPECTROMETRY AN UNKNOWN MICROORGANISM SUBGROUP FROM A SET OF REFERENCE SUBGROUPS - A method for identifying by mass spectrometry an unknown microorganism subgroup among a set of reference subgroups, including a step of constructing one knowledgebase and one classifying model per associated subgroup on the basis of the acquisition of at least one set of learning spectra of microorganisms identified as belonging to the subgroups of a group and including: constructing an adjusting model allowing mass-to-charge offsets of the acquired spectra to be corrected on the basis of reference masses-to-charges that are common to the various subgroups; adjusting the masses-to-charges of all of the lists of peaks of the learning spectra and constructing one classifying model per subgroup and the associated knowledgebase on the basis of the adjusted learning spectra. | 2019-02-14 |
20190049446 | METHOD FOR DETECTING STAPHYLOCOCCUS CONTAINED IN MILK - The object is to provide a lysis method, lysis treatment solution, detection method using an immunochromatographic device, and detection kit comprising an immunochromatographic device for detecting whether causative bacterium of mastitis is a | 2019-02-14 |
20190049447 | METHODS AND COMPOSITIONS FOR DETECTING COCCIDIOIDOMYCOSIS - Methods and compositions for detecting Coccidioidomycosis featuring amino acids 105-310 of the Cts1 protein or amino acids 111-310 of the Cts1 protein; or peptide sequences that are similar to amino acids 105-310 of the Cts1 protein or similar to amino acids 111-310 of the Cts1 protein. Compared to standard immunodiffusion testing of undiluted sera for these antibodies, the present invention shows specific detection above non-immune sera at 1:100 dilution. The methods and compositions of the present invention help reduce the non-specific antibody binding unrelated to acquiring a coccidioidal infection, thereby providing a more sensitive test for early coccidioidal infection because signal could be distinguished at lower intensity, avoiding confusion with nonspecific antibody binding. | 2019-02-14 |
20190049448 | METHOD AND DEVICE FOR IDENTIFYING CANCER - A method and device for identifying cancer is disclosed. The method includes receiving gamma photons emitted from cancer cells present in an organism through at least one photoreceptor cell. The method further includes converting the gamma photons received through the at least one photoreceptor cell to a plurality of oscillating waves having a plurality of frequencies. The method includes creating a contour plot by projecting positive and negative peaks of each of the plurality of oscillating waves. The method further includes comparing pattern of the contour plot with a plurality of training contour plots to identify type of cancer affecting at least one body part of the organism, wherein each of the plurality of training contour plots are tagged with an associated type of cancer. | 2019-02-14 |
20190049449 | MUTANT ALK KINASE IN HUMAN LUNG CANCER - Novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have now been identified in human solid tumors, e.g. non-small cell lung carcinoma (NSCLC). Secondary proteins include Echinoderm Microtubule-Associated Protein-Like 4 (EML-4) and TRK-Fusion Gene (TFG). The EML4-ALK fusion protein, which retains ALK tyrosine kinase activity, was confirmed to drive the proliferation and survival of NSCLC characterized by this mutation. The invention therefore provides, in part, isolated polynucleotides and vectors encoding the disclosed mutant polypeptides, probes for detecting it, isolated mutant polypeptides, and reagents for detecting the fusion and truncated polypeptides. The invention also provides methods for determining the presence of these mutant polypeptides in a biological sample, methods for screening for compounds that inhibit the proteins, and methods for inhibiting the progression of a cancer characterized by the mutant polynucleotides or polypeptides. | 2019-02-14 |
20190049450 | Method for Assessing and Predicting Efficacy of Breast Cancer Treatment with a Long-Acting Topoisomerase I Inhibitor - Provided is a method of treating an individual suffering from a cancer such as breast cancer by administering to the individual a long-acting topoisomerase I inhibitor, and correlating the level of one or more tumor markers in the individual with response of the cancer to treatment with the long-acting topoisomerase I inhibitor, to thereby provide a method for predicting and assessing the therapeutic efficacy of the treatment. | 2019-02-14 |
20190049451 | METHOD, BIOMARKER AND DIAGNOSTIC AGENT FOR DETECTION OF HIGH-RISK PROSTATE CANCER - [Problem] To provide a method for detecting high-risk prostate cancer, for the purpose of providing useful information, such as necessity of biopsy, to a test-positive patient in a PSA test. | 2019-02-14 |
20190049452 | TOPOGRAPHIC GENOTYPING FOR DETERMINING THE DIAGNOSIS, MALIGNANT POTENTIAL, AND BIOLOGIC BEHAVIOR OF PANCREATIC CYSTS AND RELATED CONDITIONS - The application relates to a method of a predicting the presence of invasive pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions comprising detailed molecular analysis incorporating DNA quality and quantity, K-ras mutational analysis and a broad spectrum of tumor suppressor gene linked microsatellite LOH. Methods of diagnosing, determining prognosis of and determining a course of treatment for pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions are also provided. | 2019-02-14 |
20190049453 | Classification and Treatment of Gastric Cancer - Protein and mRNA expression based methods for classification of gastric cancer, and methods of treatment based thereon. | 2019-02-14 |
20190049454 | METHODS FOR THE DIAGNOSIS AND TREATMENT OF GASTROINTESTINAL STROMAL TUMORS - The present invention relates to the diagnosis of gastrointestinal stromal tumors (GISTs). The present invention also relates to methods and compositions for the treatment of gastrointestinal stromal tumors (GISTs). | 2019-02-14 |
20190049455 | HAAH and MMP-9 are Complementary Cancer Biomarkers and Predictors of Metastasis when Combined - The present disclosure relates to methods of using biomarkers as early disease and patient outcome predictors. More particularly, the present disclosure encompasses methods of predicting cancer metastasis by detecting and/or quantifying aspartyl (asparaginyl) beta hydroxylase (HAAH) and matrix metalloproteinase 9 (MMP9) in a biological sample. | 2019-02-14 |
20190049456 | METHOD FOR DETECTING OR SEPARATING/OBTAINING CIRCULATING TUMOR CELL EMPLOYING CELL PROLIFERATION METHOD - A method for detecting or separating/obtaining CTC, which is capable of reliably and stably detecting or separating/obtaining a circulating tumor cell and a circulating tumor stem cell present in trace amounts in a biological circulating fluid such as blood or lymph, even in the state where the cancer type of the tumor cells cannot be determined yet and the state where the tumor cells are present in trace amounts in the biological circulating fluid. The method is attained by detecting or separating/obtaining CTC and/or CTSC in a biological circulating fluid, comprising treatment steps (1) to (4): (1) pretreating a sample from the biological circulating fluid to obtain a mononuclear cell phase; (2) providing a well plate in which a culture medium consisting of a serum-free cell growth medium for circulating tumor cell and/or circulating tumor stem cell has been injected, and seeding thereto the mononuclear cells obtained in step (1), followed by incubation; (3) removing the culture medium from a well of the plate obtained by the incubation in step (2); and (4) detecting or separating/obtaining an adherent tumor cell attached to the well of the plate after step (3). | 2019-02-14 |
20190049457 | IGF-1R ANTIBODY AND ITS USE FOR THE DIAGNOSIS OF CANCER - The present disclosure relates to IGF-IR (insulin like growth factor receptor-1) antibodies characterized by CDR sequences a, to be used in detection methods of IGF-IR expressing tumoral cells. | 2019-02-14 |
20190049458 | SYSTEMS, APPARATUSES, AND METHODS FOR ASSESSMENT OF LONG TERM STABILITY OF SAMPLES - A method includes receiving a sample. The method also includes applying a denaturing agent to a first portion of the sample, and detecting, in response to the application of the denaturing agent, a first measure from the first portion of the sample. The method also includes modifying the temperature of a second portion of the sample and detecting, in response to the modifying the temperature of the second portion of the sample, a second measure from the second portion of the sample. The method also includes computing thermodynamic information for the sample based on the indication of the first measure, and computing kinetic information for the sample based on the indication of the second measure. The method also includes computing, based on the thermodynamic information and the kinetic information, an indication of temporal stability of the protein component of the sample. | 2019-02-14 |
20190049459 | METHOD FOR IDENTIFYING BIOACTIVE PROTEIN, AND BIOACTIVE PROTEIN OBTAINED BY SAID METHOD - An object of the present invention is to provide a method for identifying a physiologically active protein translated from an ORF other than mORF present on mRNA. | 2019-02-14 |
20190049460 | METHOD FOR DETERMINING A CONCENTRATION OF A TARGET ANALYTE IN A SAMPLE OF BODILY FLUID - A method and an apparatus for determining a concentration of a target analyte in a sample of bodily fluid are disclosed. The method involves providing a sample of bodily fluid including the target analyte, providing an internal standard solution including a mixture of components having a plurality of isotopes of the target analyte, wherein a concentration of each isotope is unknown, adding the internal standard solution to the sample, analyzing the sample including the internal standard solution using a mass spectrometer, creating a sample function curve based on signal intensities, wherein the signal intensities define arbitrary units, transferring an analyte signal into a corresponding arbitrary analyte unit by means of the sample function curve, and transferring the arbitrary analyte unit into the concentration of a target analyte by means of a standardization function representing a curve of concentrations depending on the arbitrary units. | 2019-02-14 |
20190049461 | METHOD FOR DETECTING BASOPHIL ACTIVATION - The present invention relates to a method for diagnosing an allergy, comprising the steps of bringing into contact of basophils from a whole blood sample of a patient with an allergen in an aqueous solution in the presence of whole blood, with a volume content of whole blood in the aqueous solution of at least 20 percent by volume, under conditions that allow activation of the basophils by the allergen, enrichment of the basophils from step a) and detection of activated basophils, wherein the detection is carried out in that the expression of a marker characteristic of activated basophils is detected by means of chemiluminescence; and a kit comprising a vessel for bringing the basophils into contact with the allergen, wherein the vessel is preferably a microtiter plate, optionally an allergen, an agent for detecting a marker characteristic of activated basophils by means of chemiluminescence, wherein the agent is preferably a ligand against the marker provided with a label capable of chemiluminescence and the ligand more preferably is a monoclonal antibody, optionally an agent for stopping activation of the basophils, an optionally immobilizable ligand that binds to a polypeptide located on the cell surface of basophils independently of its activation state, wherein the ligand is preferably a monoclonal antibody against the polypeptide, and optionally an agent for lysing and/or removing erythrocytes. | 2019-02-14 |
20190049462 | LIGHT-ACTIVATED CATION CHANNEL AND USES THEREOF - The present invention provides compositions and methods for light-activated cation channel proteins and their uses within cell membranes and subcellular regions. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-activated cation channels to specific cells or defined cell populations. In particular the invention provides millisecond-timescale temporal control of cation channels using moderate light intensities in cells, cell lines, transgenic animals, and humans. The invention provides for optically generating electrical spikes in nerve cells and other excitable cells useful for driving neuronal networks, drug screening, and therapy. | 2019-02-14 |
20190049463 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF - The present invention relates to the field of GPCR structure biology and signaling. In particular, the present invention relates to protein binding domains directed against or capable of specifically binding to a functional conformational state of a G-protein-coupled receptor (GPCR). More specifically, the present invention provides protein binding domains that are capable of increasing the stability of a functional conformational state of a GPCR, in particular, increasing the stability of a GPCR in its active conformational state. The protein binding domains of the present invention can be used as a tool for the structural and functional characterization of G-protein-coupled receptors bound to various natural and synthetic ligands, as well as for screening and drug discovery efforts targeting GPCRs. Moreover, the invention also encompasses the diagnostic, prognostic and therapeutic usefulness of these protein binding domains for GPCR-related diseases. | 2019-02-14 |
20190049464 | BLOOD BIOMARKER FOR DETECTING ARTERIOSCLEROSIS - Novel means capable of detecting an arteriosclerotic lesion in a body by a less invasive, simple method is disclosed. The method for detecting arteriosclerosis according to the present invention comprises measuring the myosin heavy chain 11 level in a blood sample isolated from a subject. A myosin heavy chain 11 level higher than that of a healthy individual is indicative of the presence of arteriosclerosis in the subject. Since the present invention enables detection of arteriosclerosis by a blood test, a less invasive, simple test can be carried out. Unlike methods for testing only particular regions such as carotid artery ultrasonography, the present invention is expected to reflect the conditions of blood vessels in the whole body. | 2019-02-14 |
20190049465 | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF AGE-RELATED MACULAR DEGENERATION - The present invention is related to diagnostic, treatment and compound screening methods related to dry age-related macular degeneration (dry AM D). In select embodiments, the methods comprise determining expression or activity levels of NAD-dependent deacetylase sirtuin-1 (SI RT-1), AM P-activated protein kinase (AM PK), poly(adenosine diphosphate ribose) poly-merase-2 (PARP2), peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-Iα) and/or mRNA levels of RAC-gamma serine/threonine-protein kinase (AKT3). In general, higher levels of PARP2, lower levels of PGC-Iα or AKT3 and/or higher acetylation levels of PGC-Iα in the samples are indicative that the subject or cells from which the samples are obtained are susceptible or are suffering from dry AMD. | 2019-02-14 |
20190049466 | BIOMARKERS FOR THE EARLY DETECTION OF PARKINSON'S DISEASE - Disclosed are biomarkers for Parkinson's disease (PD), including idiopathic PD (idPD). The present invention relates generally to assays, kits, compositions, solid supports and methods that measure a decrease in the expression or function of PLA2g6(L) variant of PLA2g6 (PARK 14) gene in a sample from the subject, including non-neuronal cells as a biomarker for preclinical (prodromal) or early stage Parkinson's disease (PD) and idiopathic PD (idPD), as well as assays, kits, compositions and methods that can detect the functional consequences of decreased expression of PLA2g6(L), including decreased store operated Ca2+ entry (SOCE), deficit of Ca2+ in endoplasmic reticulum stores, and autophagic dysfunction in the cells obtained from the subjects in preclinical (prodromal) and early stage PD diagnosis and for monitoring Parkinson's Disease progression. | 2019-02-14 |
20190049467 | EXOSOMAL TAU AS A BIOMARKER FOR BRAIN DISORDERS - Disclosed are methods, compositions, devices, and kits for the isolation of brain-specific exosomes. Specifically, methods, compositions, devices, and kits comprising an isolated brain-specific extracellular vesicle or exosome joined to a first binding agent that is specific for tau, β-amyloid, S100 β, neuron-specific enolase, glycoprotein A2B5, CD133, NQ01, synaptophysin, neuronal nuclei, MAB1569, polysialic acid-neural cell adhesion molecule (PSA-NCAM), or neurogenic differentiation 1 (NeuroD or Beta2), or glycosylated or phosphorylated forms of these molecules, are provided. | 2019-02-14 |
20190049468 | APPARATUS, METHOD, AND PROGRAM FOR COMPONENT MEASUREMENT - Provided is a component measuring apparatus configured to determine a functional form that describes wavelength characteristics of a variation attributable to scattering (S (λ)). The apparatus then determines unknown one or more coefficients (p, q) based on a first relational expression that involves a variation attributable to absorption (H (λ | 2019-02-14 |
20190049469 | BIOMARKER FOR USE IN TREATING ANEMIA - Provided herein are methods of treating diseases associated with anemia or ineffective erythropoiesis by using the level and/or activity of a ligand of an activin receptor, in particular, Growth differentiation factor 11 (GDF11), as an indicator of responsiveness of a patient to the treatment, efficacy of the treatment, or appropriate dosage for the treatment with an activin type II receptor inhibitor. | 2019-02-14 |
20190049470 | METHOD FOR DIAGNOSING OR MONITORING KIDNEY FUNCTION OR DIAGNOSING KIDNEY DYSFUNCTION - A method for (a) diagnosing or monitoring kidney function in subject or (b) diagnosing kidney dysfunction in a subject or (c) predicting or monitoring the risk of an adverse events in a diseased subject or (d) predicting or monitoring the success of a therapy or intervention comprising
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20190049471 | Composition and Methods for Assessing Sensitivity and Specificity of Antibody Detection Reagents - Compositions and methods which are useful for determining the sensitivity and specificity of antibody detection reagents are disclosed. | 2019-02-14 |
20190049472 | FOOD ALLERGY BIOMARKER, FOOD ALLERGY TESTING METHOD, KIT FOR URINE SAMPLE TESTING, AND STICK FOR URINE SAMPLE TESTING - This biomarker is a biomarker for testing a food allergy, and comprises at least one species selected from the group consisting of LTE | 2019-02-14 |
20190049473 | METHODS AND COMPOSITIONS FOR USING SOLVATOCHROMIC DYES TO DETECT THE PRESENCE OF HOMEOPATHIC POTENCIES - A method is provided for obtaining a characteristic of a homeopathic preparation, particularly its potency. In particular aspects, solvatochromic dyes may be used for detection of a homeopathic preparation. | 2019-02-14 |
20190049474 | TESTING SYSTEM AND METHOD OF STARTING TESTING SYSTEM - A testing system according to one or more embodiments may include: a smear preparing apparatus that prepares a smear slide by smearing a sample on a glass slide; a smear transporting apparatus that transports the smear slide; a controller; and a display part. The controller may cause the display part to display a selection screen on which one or more of the smear preparing apparatus and the smear transporting apparatus can be selected. Based on a selection on the selection screen, the one or more of the smear preparing apparatus and the smear transporting apparatus selected on the selection screen may run respective start operations. | 2019-02-14 |
20190049475 | CHAIN OF CUSTODY FORMS AND METHODS - A chain-of-custody form having integrated removable specimen seals and methods for using the form to identify a test sample collected from a donor and document the handling of the test sample. The form comprises a blank having a first portion and a second portion. The first portion comprises a first section having one or more spaces for recording demographic and testing information, and one or more indicia of the information to be recorded in one or more marked spaces; and a second section having a marked space for the donor to affix a signature and one or more indicia of the purpose of the space. An identifier that is unique to the form is recorded within the first portion and within the second portion. The identifier includes an specimen identification number or some other method of specimen identification such as a bar-code. | 2019-02-14 |
20190049476 | SAMPLE RACK TRANSPORT APPARATUS, SAMPLE ANALYSIS DEVICE, AND SAMPLE ANALYSIS SYSTEM - A sample rack transport apparatus for transporting a sample rack to a sample analyser, comprising: a bidirectional transmission track for bidirectionally transmitting a sample rack without passing through the sample analyser; a feed channel in parallel with the bidirectional transmission track, wherein the sample rack may be delivered from the bidirectional transmission track to the feed channel and to the sample analyser; an unloading cache region located between the bidirectional transmission track and the feed channel, the unloading cache region being used for storing the sample tack; and an unloading mechanism for delivering the sample rack in the feed channel to the unloading cache region for storage, or delivering the sample rack stored in the unloading cache region to the bidirectional transmission track. Also provided are a sample analysis device and a sample analysis system using the sample rack transport apparatus. | 2019-02-14 |
20190049477 | AUTOMATIC ANALYZER AND CLEANING METHOD - The invention provides a highly reliable automatic analyzer and dispenser probe cleaning method that allows for the removal of leftover cleaning water from the outer wall surfaces of a probe without increasing the size of a cleaning bath and contaminating the outer wall surfaces of the probe. A cleaning bath | 2019-02-14 |
20190049478 | VIAL-HANDLING MECHANISM FOR AN AUTOMATED KARL FISCHER TITRATION SYSTEM - A mechanism ( | 2019-02-14 |
20190049479 | SYSTEMS AND METHODS OF MOTION DETECTION USING DYNAMIC THRESHOLDS AND DATA FILTERING - Systems and methods of detecting human movement with a sensor are provided, including generating a motion event signal in response to movement detected by the sensor, and generating a parameterized curve to represent the detected motion. The parameterized curve is fit to a predetermined window of sensor data captured by the sensor to filter the motion event signal. A noise magnitude estimate and a curve fit error is determined based on the fitted parameterized curve to the predetermined window. A detection threshold value is determined based on the curve fit error, a noise source signal estimate of known noise, and zero or more noise magnitudes from other sources. Human motion is determined by correlating a true motion event signal with human motion based on a comparison between a value of a point on the parameterized curve and the detection threshold value. | 2019-02-14 |
20190049480 | APPARATUS FOR DETECTING WIND DIRECTION - An apparatus for detecting wind direction includes an attachment member, an elongated member, a vertical member, and a wind direction indicator. The elongated member extends outward from the attachment member. The vertical member is coupled to the elongated member. The wind indicator is coupled to the vertical member and includes a bottom surface, a top surface opposite the bottom surface, and first and second sides extending from the bottom surface to the top surface. The wind indicator further includes a first fin and a second fin, each extending from the top surface and having a forward portion and an aft portion. A first distance between the respective aft portions of the first and second fins is greater than a second distance between the respective forward portions of the first and second fins such that the first and second fins converge toward one another at an acute angle. | 2019-02-14 |
20190049481 | INTEGRATED LINEAR AND ANGULAR MEMS ACCELEROMETERS - An electromechanical system (MEMS) accelerometer is described. The MEMS accelerometer may be configured to sense linear acceleration along one, two or three axes, and to sense angular acceleration about one, two or three axes. As such, the MEMS accelerometer may serve as 2-axis, 3-axis, 4-axis, 5-axis or 6-axis inertial accelerometer. In some embodiments, the MEMS accelerometer may comprise a single mass connected to at least one anchor via a plurality of tethers. In other embodiments, the MEMS accelerometer may comprise a proof mass connected to at least one anchor via a plurality of tethers and one or more shuttle masses connected to the proof mass via a second plurality of tethers. Rotational and linear motion of the MEMS accelerometer may be sensed using capacitive sensors. | 2019-02-14 |
20190049482 | DIFFERENTIAL Z-AXIS RESONANT MEMS ACCELEROMETERS AND RELATED METHODS - A MEMS resonant accelerometer is described. The MEMS resonant accelerometer may comprise a pair of proof masses configured to resonate when driven with periodic signals. In this respect, the accelerometer's proof masses may serve as masses for detecting accelerations as well as resonators. The MEMS resonant accelerometer may comprise drive electrodes for causing the proof masses to resonate and sense electrodes for sensing motion of the proof masses. The magnitude of a z-axis acceleration, that is, an acceleration perpendicular to the plane of the proof masses, may be detected by sensing the frequency at which the proof masses resonate in the presence of such an acceleration. The proof masses may be arranged to produce differential signals. | 2019-02-14 |
20190049483 | PHYSICAL QUANTITY SENSOR, COMPLEX SENSOR, INERTIAL MEASUREMENT UNIT, PORTABLE ELECTRONIC DEVICE, ELECTRONIC DEVICE, AND VEHICLE - A physical quantity sensor includes a sensor element, and a container (package) that stores the sensor element on a bottom plate (first base material). An outer edge of the container has a rectangular shape in a plan view. Lengths of each side of the rectangular shape are 2.0 mm or more and 7.0 mm or less, a thickness of the container is 0.50 mm or more and less than 1.85 mm, and when a thickness of the bottom plate is t, 0.4 mm≤t≤1.1 mm is satisfied. | 2019-02-14 |
20190049484 | Physical Quantity Sensor, Inertial Measurement Unit, Electronic Apparatus, And Vehicle - A physical quantity sensor includes: a container that includes a storage space and a bottom plate that configures an inner bottom surface of the storage space; a sensor element that is attached to the inner bottom surface; a circuit element that is attached to a surface of the sensor element on the opposite side of the inner bottom surface, and is electrically connected with the sensor element; and a ground plane that is provided on the bottom plate. The ground GND plane is provided apart from the inner bottom surface. | 2019-02-14 |
20190049485 | DYNAMIC SELF-CALIBRATION OF AN ACCELEROMETER SYSTEM - One embodiment includes a method for dynamic self-calibration of an accelerometer system. The method includes forcing a proof-mass associated with a sensor of the accelerometer system in a first direction to a first predetermined position and obtaining a first measurement associated with the sensor in the first predetermined position via at least one force/detection element of the sensor. The method also includes forcing the proof-mass to a second predetermined position and obtaining a second measurement associated with the sensor in the second predetermined position via the at least one force/detection element of the sensor. The method further includes calibrating the accelerometer system based on the first and second measurements. | 2019-02-14 |
20190049486 | Characterizing a Height Profile of a Sample by Side View Imaging - A scanning probe microscope, in particular an atomic force microscope, for analyzing a sample by moving a probe and the sample relative to one another, wherein the scanning probe microscope includes a detection unit with a side view camera arranged and configured for detecting an image of the sample in a substantially horizontal side view, and a determining unit for determining information indicative of a profile of at least part of a surface of the sample based on the detected image. | 2019-02-14 |
20190049487 | ELECTRICAL TESTING JIG - An electrical testing jig includes: a substrate; a first bracket on the substrate, the first bracket having a first step extending in a first direction on a top of the first bracket; and a second bracket on the substrate, the second bracket being spaced apart from the first bracket in a second direction perpendicular to the first direction and having two second steps spaced apart from each other in the first direction on a top of the second bracket. Each of the second steps is angular. | 2019-02-14 |
20190049488 | OSCILLOSCOPE AND METHOD FOR OPERATING AN OSCILLOSCOPE - An oscilloscope comprises at least one analog input channel configured to receive and process an analog input signal, at least one digital input channel configured to receive and process a digital input signal, and a trigger unit. Said trigger unit is connected with said at least one analog input channel and said at least one digital input channel. Said trigger unit is configured to detect predetermined trigger events in both said analog input signal and said digital input signal. Said trigger unit further is configured to control data acquisition based on a combination of at least two trigger events detected in said analog input signal and said digital input signal. Moreover, a method for operating an oscilloscope is disclosed. | 2019-02-14 |
20190049489 | DIFFERENTIAL CURRENT SENSING BUSSING METHOD - The line power and neutral conductors for a circuit interrupter such as a miniature circuit breaker, using ground fault sensing via a current transformer, are arranged as a rigid conductor formed from a flat plate and surrounding and holding an insulated flexible conductor when passing through the Ground Fault Interrupter current transformer. The rigid conductor can provide a shaped current path to maximize the effectiveness of the current transformer. | 2019-02-14 |
20190049490 | Fault Waveform Recording Device - In a fault waveform recording device, a first storage stores data detected in a power system, the data being up-to-date and indicating an electrical quantity during a first period, and halts the updating of the data stored in the first storage after a second period has elapsed since an abnormality detection time at which an abnormality in the power system is detected. The second period is shorter than the first period. First operation unit stores data in a first interval as is into a second storage, among the data of the first period stored in the first storage after the updating of the data stored in the first storage is halted, the first interval including the abnormality detection time, and decimates data in a second interval different from the first interval. | 2019-02-14 |
20190049491 | DEVICE FOR MEASURING AN ELECTRICAL QUANTITY OF ONE PHASE OF AN AC ELECTRIC CURRENT OF AN OVERHEAD ELECTRICAL NETWORK - The invention relates to a device for measuring an electrical quantity of one phase of an AC electric current in an overhead electrical network, comprising: a sensor designed to be attached to an electric line of the overhead electrical network, said sensor including: an electrically conductive plate; an electrical conductor, designed to electrically connect the plate to the electric line, in order to circulate a first electric current from the electric line through the electrical conductor; a processing unit, designed to determine the electrical quantity from a value of the first electric current and a value of a capacitance between the plate and the ground. Said device also comprises a generator, electrically connected to the electrical conductor and designed to inject a second electric current through the electrical conductor, said second electric current having a frequency other than the frequency of the first electric current, the processing unit also being designed to calculate the value of the capacitance between the plate and the ground as a function of a value of the second electric current. | 2019-02-14 |
20190049492 | System and Method of Power Grid Monitoring - The application discloses a method and apparatus for determining an operational status of one or more power grid components ( | 2019-02-14 |
20190049493 | AC ELECTRICAL POWER MEASUREMENTS - An electrical measurement device for monitoring the current and power taken by a plurality of electrical loads that may be powered by a selected one of multiple AC power sources comprises sampling the voltage of said sources and the current taken by said loads at a integral number of samples per cycle at sample times determined by an independent processor clock. The integral number of samples of each measured parameter for each cycle are processed to determine a complex number for each parameter representative of the amplitude and the phase relative to the independent processor clock. The phase drift of the substantially constant source voltages may be determined as a measure of frequency of the sources, and may be used to cancel drift of the current measurement to enable averaging. When the source feeding a load is changed, the phase drift is removed from its current measurement by selecting the voltage samples of the source now feeding it to use for drift cancellation or for average power computation and cumulative energy computation. | 2019-02-14 |
20190049494 | MICROCONTROLLER INCLUDING POWER SUPPLY MONITORING - A microcontroller is operable to monitor power supply levels corresponding, respectively, to a first power supply (e.g., a main power supply) and a second power supply (e.g., a battery backup power supply). In one or more modes of operation, the same brownout detector in the microcontroller alternately monitors signals corresponding, respectively, to the first and second power supply levels. | 2019-02-14 |
20190049495 | TECHNIQUES FOR CONTROL OF QUANTUM SYSTEMS AND RELATED SYSTEMS AND METHODS - According to some aspects, a waveform processor is provided for control of quantum mechanical systems. Some embodiments of the waveform processor may be used to control quantum systems used in quantum computation, such as qubits. According to some embodiments, a waveform processor may include a first sequencer configured to sequentially execute master instructions according to a defined order and output digital values in response to the executed master instructions, and a second sequencer coupled to the first sequencer and configured to generate analog waveforms at least in part by transforming digital waveforms according to digital values received from the first sequencer. The analog waveforms may be applied to a quantum system. In some embodiments, the waveform processor may further include a waveform analyzer configured to integrate analog waveforms received from a quantum system and output results of said integration to the first sequencer. | 2019-02-14 |
20190049496 | SYSTEMATIC METHODOLOGY TO REMOVE REFLECTIONS FROM I/O MEASUREMENTS - Embodiments of the present invention reconstruct a waveform at a receiver-end of a channel from an observed waveform physically measured at a probe point near the middle of the channel, where the channel is corrupted by reflections. The channel may be a memory channel of a high-speed I/O interface, for example. Equations to derive the waveform may be created using linear network analysis and/or signal processing, for example. S-parameters may be derived from simulated models representing components from the probe point to the load. The s-parameters together with the load impedance are used to recreate the desired waveform free from corruption due to reflections. | 2019-02-14 |
20190049497 | ISLANDING DETECTION IN AN ELECTRICAL POWER GRID - A method for islanding detection in an electrical power grid supplied by an electrical power source. The method includes measuring an output voltage (V | 2019-02-14 |
20190049498 | SEMICONDUCTOR INTEGRATED CIRCUIT AND SIGNAL PROCESSING METHOD - The present disclosure relates to a semiconductor integrated circuit and a signal processing method that can improve measurement accuracy. Pulses subjected to pulse generation and disconnection control by a control circuit are supplied to a pulse distribution circuit and a CP circuit. The pulse distribution circuit divides one pulse into two or more pulses that do not overlap each other, and supplies the pulses to a CBCM circuit. The CBCM circuit is configured by connecting a capacitance element to be measured to the output of a measurement core circuit called a pseudo inverter. The CP circuit inputs, to the gate electrode, pulses that cause a channel of a non-measurement MISFET to change from the accumulation state to the inverted state, and monitors, from the substrate side, a CP current flowing through a trap acting as a recombination center of the gate insulating film and the semiconductor substrate interface. The present disclosure can be applied to, for example, a semiconductor integrated circuit for evaluating the characteristics of the gate insulating film of the MISFET. | 2019-02-14 |
20190049499 | METHOD AND DEVICE FOR MEASURING AT LEAST ONE PROPERTY OF A COIL, METHOD AND DEVICE FOR MEASURING THE POSITION OF AN ACTUATION MEMBER, AND MOTOR VEHICLE - A method for measuring a property of a measuring coil, which is modeled as a parallel circuit including a capacitance with a series circuit including a DC voltage resistance, a frequency-dependent resistance, and an inductance, and a current-voltage converter is connected in series, by performing: applying an AC voltage, having a first frequency and having a DC voltage component differing from zero, to the coil and a voltage at the current-voltage converter is captured at a second frequency which is a multiple of the first frequency, wherein the multiple is an n-tuple, and the impedance and the phase angle at the first frequency are derived from at least n measured values captured in succession; and applying an AC voltage, having a third frequency differing from the first frequency and having a DC voltage component differing from zero, to the coil and the voltage at the current-voltage converter is captured at the second frequency or at a fourth frequency which is a multiple of the fourth frequency, wherein the multiple is an m-tuple, and the impedance and the phase angle at the third frequency are derived from m measured values captured in succession; at least one of the values for the DC voltage resistance, the frequency-dependent resistance, and the inductance being derived from the impedances and the phase angles. | 2019-02-14 |
20190049500 | LIGHTNING STRIKE PREDICTION SYSTEM BASED ON RADIO RECEIVER STATIC - A system for predicting a triggered lightning strike upon an aircraft, which includes an antenna for collecting an RF signal. The system includes one or more processors and a memory coupled to the processor, the memory storing data into a database and program code that, when executed by the one or more processors, causes the system to receive as input a filtered, amplified form of the RF signal collected by the antenna and a non-filtered, amplified form of the RF signal collected by the antenna. The system determines a difference between the filtered, amplified form of the RF signal and the non-filtered and amplified form of the RF signal. The difference is a static signal. The system determines the triggered lightning strike upon the aircraft based on the static signal. | 2019-02-14 |
20190049501 | MEASURING DEVICE AND MEASURING METHOD WITH MULTI-BEAM BEAMFORMING - A measuring device comprising a plurality of analog signal adjusters, and an antenna array, comprising a plurality of antennas is provided. Each of the plurality of antennas is connected to exactly one of the plurality of analog signal adjusters. The analog signal adjusters are adapted to alter the phase and/or amplitude of signals sent and/or received by the plurality of antennas, generating an antenna characteristic of the antenna array comprising at least a first beamforming beam or a first plane wave and a second beamforming beam or a second plane wave. | 2019-02-14 |
20190049502 | METHOD FOR MEASURING BEAM STEERING CHARACTERISTICS AND MEASUREMENT SYSTEM - A method for measuring beam steering characteristics of a device under test using a measurement system comprising a probe array with at least two field probes. The field probes can be arranged at different angles with respect to the device under test. A reference unit for calibrating the probe array is provided. At least two calibration measurements with different main radiation directions of the reference unit are performed wherein a predefined number of field probes of the probe array is used for measuring the radiation pattern of the reference unit. A calibration dataset for at least each field probe of the predefined number of field probes and each radiation direction is generated and stored. The reference unit is replaced by a device under test such that the device under test is located at the same measurement position as the reference unit was during the calibration measurements. A measurement of the device under test is performed by using the predefined number of field probes of the probe array. | 2019-02-14 |
20190049503 | Transport Unit Having At Least One Installation - A transport unit, in which a rapid and precise fault localization can be achieved, includes an installation, a simulation device with an interface, through which current status data of the installation can be received, and a computing unit configured determine or acquire simulated status data on the basis of simulation data and the current status data, which are representative for a status of at least a part of the installation. A method for controlling an installation in a transportation unit, in particular a rail vehicle, is also provided. | 2019-02-14 |
20190049504 | TESTING SYSTEM FOR AN ELECTRICAL CABLE - A testing system may include an electrical cable, a computing device, a communication interface, at least one downstream device, and testing software. The communication interface may be coupled to the electrical cable and to the computing device. The at least one downstream device may be coupled to the electrical cable. The testing software may be stored on the computing device. The testing software may be configured to initiate and evaluate transfer of data between the computing device and the at least one downstream device through the electrical cable and the communication interface. | 2019-02-14 |
20190049505 | SYSTEM AND METHOD FOR USING A CONNECTOR AT THE END OF A CABLE AS A CABLE LOCATING TONE SENSOR - A system for use in locating and testing a cable having a first end connected to a first connector and a second end connected to a second connector where the second connector is one of a plurality of connectors within a patch panel. The system includes a first device having a first cable certification and test circuitry which is couplable to the first connector and a second device having a second cable certification and test circuitry which is couplable to the second connector. One of the first device and the second device further includes circuitry for generating a tone signal that is to be applied to the cable and the other one of the first device and the second device further includes a probe for receiving the tone signal and for generating an output indicative of a strength of the received tone signal. | 2019-02-14 |
20190049506 | Safety Ground Wire Monitoring And Alarm Systems - A system for monitoring the integrity of a plurality of ground conductors has a plurality of monitors, with a different monitor associated with each ground conductor. Each monitor includes a voltage sensor which monitors voltage on a closed circuit of the monitor. Upon the voltage sensor sensing an unexpected voltage, a transmitter of the monitor issues an “alarm” signal, which may be wireless (e.g., being sent using LoRaWAN protocol). The transmitter may issue other signals, including a periodic “heartbeat” signal to confirm continued operation of the monitor, and a “movement” signal to indicate movement of the monitor. The monitor may be GPS-enabled, in which case each signal may include the GPS coordinates of the monitor. The signals issued by the transmitter may ultimately be analyzed by an operator via a user interface platform, which may simultaneously display information regarding two or more of the plurality of monitors. | 2019-02-14 |
20190049507 | ELECTRIC GROUND FAULT DETECTION SYSTEM AND METHOD - A system for testing a ground fault detection system in an electric circuit establishes a ground connection between a bus and the ground via an inverter and a load by closing an inverter switch of the inverter and a grounding switch disposed between the load and the ground, determines whether the ground connection is detected, and determines a fault in the ground fault detection system responsive to the first ground connection not being detected by the ground fault detection system. Optionally, a ground fault may be identified by determining three phase voltages provided from each of plural inverters, determining symmetrical components of the three phase voltages for each of the inverters, and identifying a ground fault in one or more of the inverters while powered by the power supply based on the symmetrical components. | 2019-02-14 |