07th week of 2014 patent applcation highlights part 42 |
Patent application number | Title | Published |
20140045197 | BIOMARKERS USED TO DETECT AND MONITOR NEUROLOGICAL AUTOIMMUNE DISEASES - Biomarkers of neurological autoimmune diseases are described, and methods of using such biomarkers also are described. | 2014-02-13 |
20140045198 | METHOD OF PREDICTING THE EVOLUTION OF A PATIENT SUFFERING OF STROKE - The invention is a method of predicting the evolution of a patient suffering of a neurovascular disease, preferably stroke, comprising obtaining a biological sample of said patient, assessing in said biological sample the level of endostatin and FasL, determining whether said levels of endostatin and FasL together are above or below predetermined cut-off levels and predicting the functional outcome of said neurovascular disease on said patient evaluating the result of the previous step. The combination of endostatin and FasL is a more powerful predictor that any clinical prognostic tool and adds significant prognostic value to all other clinical variables of the art. | 2014-02-13 |
20140045199 | ANTI-VE-CADHERIN AUTOANTIBODIES AS A BIOMARKER OF VASCULAR ALTERATIONS ASSOCIATED WITH DISORDERS - The present invention relates to a method for predicting and/or diagnosing vascular alterations associated with a disorder in a patient, comprising a step of detecting or quantifying the presence of anti-VE-cadherin autoantibodies in a biological sample obtained from said patient as well as a kit suitable for carrying out such method. | 2014-02-13 |
20140045200 | PREDICTING MORTALITY AND DETECTING SEVERE DISEASE - Measurement of circulating ST2 and/or IL-33 concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, and the detection of severe disease. | 2014-02-13 |
20140045201 | METHOD FOR QUANTIFYING CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN 2, AND REAGENT KIT FOR THE METHOD - Disclosed is a method for quantifying HDL2 cholesterol in a test sample without requiring laborious operations. The method for quantifying cholesterol comprises allowing phospholipase to act on HDL to quantify cholesterol. Also disclosed is a method comprising: a first step of transferring cholesterols other than high-density lipoproteins in a test sample to the outside of the reaction system; and a second step of quantifying high-density lipoprotein 2 cholesterol among the high-density lipoproteins remaining in the reaction system; wherein, by performing the second step by the above method, high-density lipoprotein 2 cholesterol in the test sample can be quantified. | 2014-02-13 |
20140045202 | Analyte Sensors and Methods for Making and Using the Same - The present disclosure provides an analyte sensor that includes a conductive calibration pattern which provides species-specific calibration information to a meter. Also provided, are analyte sensors comprising a layer of absorbent material disposed on a first major surface of a first substrate and/or a second major surface of a second substrate. Methods for making and using the analyte sensors are also provided. | 2014-02-13 |
20140045203 | TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE - The invention relates to a test element for detecting at least one analyte in a sample, in particular for detecting at least one metabolite in a bodily fluid. The test element comprises at least one test field with a test field surface. The test field comprises at least one detection reagent that is adapted to undergo a detectable reaction in the presence of the analyte. The test element further comprises at least one distribution element that has at least one distribution surface facing the test field surface. Between the distribution surface and the test field surface is at least one capillary gap, wherein the capillary gap is adapted to allow a layer of the sample with a layer thickness of no more than 50 μm to form within the capillary gap. | 2014-02-13 |
20140045204 | EVALUATION OF COPOLYMER DIETHYLAMIDE - Methods of analyzing glatiramer acetate (GA) or a polymeric precursor thereof are provided. The methods can include determining a level of one or more diethylamide-modified amino acids in a sample comprising GA or a polymeric precursor thereof, and selecting at least a portion of the sample based on the assessment of the one or more diethylamide-modified amino acids in the sample. | 2014-02-13 |
20140045205 | GLUTAMYL AMINOPEPTIDASE AS A MARKER OF RENAL DAMAGE - The present invention relates to a method and a kit for the diagnosis and/or prognosis of kidney injury comprising analysing a sample obtained from a patient and determining the activity of at least one aminopeptidase selected from aspartyl aminopeptidase, glutamyl aminopeptidase, alanyl aminopeptidase and leucyl-cystinyl aminopeptidase. | 2014-02-13 |
20140045206 | APPARATUS AND METHOD FOR SEPARATING MATERIALS OF DIFFERENT DENSITIES - A device for separating materials of different densities is provided. A cup body has an internal cavity configured to hold media. An inner wall defines a central body region having an upper and lower end. The upper end is wider than the lower end. An interior shoulder circumscribes the upper end of the central body region. The interior shoulder defines a neck region above the central body region and a shoulder trap below the neck region. The shoulder trap circumscribes the upper end of the central body region and is wider than the neck region. When the device is spun about a central axis, the media travels upward along the inner wall toward the shoulder trap. Relatively more dense material in the media is collected in the shoulder trap, and relatively less dense material is expelled from the device through an opening above the neck region. | 2014-02-13 |
20140045207 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES - Provided are modified cycloalkyne compounds; and methods of use of such compounds in modifying biomolecules. Embodiments include a cycloaddition reaction that can be carried out under physiological conditions. The cycloaddition reaction involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo and in vitro. | 2014-02-13 |
20140045208 | Solid Phase Cell Isolation and/or Enrichment Method - The present invention concerns a solid phase method for isolating and/or enriching predetermined cells from a sample. Such a methods are use e.g. to isolate and enrich predetermined cells like fetal cells from a sample of maternal peripheral blood, tumor cells from a sample of body fluid or stem cells from a fluid or fluidized sample of body tissue or body fluid. The solid phase isolation method of the present invention is used for isolating predetermined cells from a sample containing such predetermined cells by binding the predetermined cells to a solid surface. According to the invention the sample is contacted with the solid surface and then removed from the solid surface, wherein the sample or a washing buffer contains a polyol during or after contacting the sample with the solid surface. | 2014-02-13 |
20140045209 | Structures for Enhancement of Local Electric Field, Light Absorption, Light Radiation, Material Detection and Methods for Making and Using of the Same - Microstructures and nanostructures ( | 2014-02-13 |
20140045210 | MICROPLATE READER WITH LID LIFTER FOR MICROPLATES - Microplate reader with optical measuring/detection device has housing, a microplate support and a moving unit. The moving unit moves the microplate support out and into the housing and horizontally within the housing. The reader has an integrated lid holding apparatus within the housing for lifting and placing a microplate lid on the microplate. The lid holding apparatus moves the microplate lid and/or the microplate support for moving the microplate in one respective vertical direction. A method for optically measuring a microplate in such a microplate reader places a covered microplate on the microplate support, retracts it into the housing, lifts the lid from the microplate, measures the microplate with the lifted lid, replaces the lid, and extends the support and the covered microplate out of the housing. | 2014-02-13 |
20140045211 | HIGH LEVEL PRODUCTION OF RECOMBINANT PROTEINS - The present technology relates to the fields of biochemistry, molecular biology and medicine. In particular, the present technology relates to methods and compositions for increased expression of recombinant proteins. | 2014-02-13 |
20140045212 | GAL ALPHA 1-3GAL-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS DERIVED FROM CHO CELLS - The present invention provides methods of evaluating CHO cells. | 2014-02-13 |
20140045213 | TARGETING POLY-GAMMA-GLUTAMIC ACID TO TREAT STAPHYLOCOCCUS EPIDERMIDIS AND RELATED INFECTIONS - Immunogenic compositions and methods for eliciting an immune response against | 2014-02-13 |
20140045214 | MUTANT MICROORGANISM BELONGING TO THE GENUS TRICHODERMA AND METHOD FOR PRODUCING PROTEIN USING THE SAME - An object of the present invention is to provide a mutant microorganism belonging to the genus | 2014-02-13 |
20140045215 | NEUTRALIZING ANTI-CCL20 ANTIBODIES - The present invention relates to novel humanized, chimeric and murine antibodies that have binding specificity for the human CC chemokine ligand 20 (CCL20). The present invention further relates to heavy chains and light chains of said antibodies. The invention also relates to isolated nucleic acids, recombinant vectors and host cells that comprise a sequence which encodes a heavy chain and/or a light chain of said antibodies, and to a method of preparing said antibodies. The anti-CCL20 antibodies of the invention can be used in therapeutic applications to treat, for example, inflammatory and autoimmune disorders and cancer. | 2014-02-13 |
20140045216 | NOVEL SIGNAL SEQUENCES TO IMPROVE PROTEIN EXPRESSIONS AND SECRETION OF RECOMBINANT ENZYMES AND OTHER PROTEINS - Polypeptide signal sequences of modified fragments of human immunoglobulin heavy chain binding protein (Bip) are disclosed. Also disclosed are fusion proteins comprising a modified fragment of human immunoglobulin heavy chain binding protein (Bip) operably linked to a heterologous polypeptide. Also disclosed are protein expression vectors comprising a promoter operably linked to a first DNA sequence encoding a signal sequence comprising a modified fragment of human immunoglobulin heavy chain binding protein (Bip) and a second DNA sequence encoding a heterologous polypeptide fused in frame to the first DNA sequence. Further disclosed are methods of producing a polypeptide comprising expressing a fusion protein comprising a polypeptide signal sequences of modified fragments of human immunoglobulin heavy chain binding protein (Bip) operably linked to a heterologous polypeptide and recovering the heterologous polypeptide. | 2014-02-13 |
20140045217 | Novel Algae Extraction Methods - The present disclosure provides novel methods and compositions for improved production processes of algae cell components. In particular the present disclosure relates to methods for improving the extractability of algae cellular compositions. | 2014-02-13 |
20140045218 | HYDROPHILIC MODIFICATION OF WATER INSOLUBLE POLYSACCHARIDE AS SURFACE-ACTIVE AGENTS - A surfactant produced by reacting naturally occurring polysaccharides that are not water soluble with a hydrophilic substituent on a carboxylic portion of the polysaccharide. In a second reaction, the surfactant is further substituted on a hydroxylic portion with a hydrophobic or lipophilic substituent, so as to make the reaction product both water soluble and capable of attracting oily material that is hydrophobic to be removed from a substrate by cleaning in water. Methods of making the surfactant and the follow-on reaction product are described. | 2014-02-13 |
20140045219 | Method for Producing Substance Utilizing Microorganism - In a method for producing a target substance utilizing a microorganism comprising culturing the microorganism in a medium to produce and accumulate the target substance in the medium and collecting the target substance, microorganism is employed, which is a mutant strain or a genetic recombinant strain constructed from a parent strain of the microorganism having a respiratory chain pathway of high energy efficiency and a respiratory chain pathway of low energy efficiency as respiratory chain pathways, and having either one or both of the following characteristics: (A) the respiratory chain pathway of high energy efficiency is enhanced, (B) the respiratory chain pathway of low energy efficiency is deficient. | 2014-02-13 |
20140045220 | COMPOSITION FOR BIOSAMPLE TREATMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION USING THE SAME - A composition for a biosample treatment and method for nucleic acid amplification using the same are provided. The composition for biosample treatment includes at least one halocarbon, at least one polyether and at least one surfactant. The composition contains 1˜70% by weight of the halocarbon based on the total weight of the composition. Accordingly, a biosample can be lysed and homogenized in a single tube at one step. Furthermore, reagents for use in nucleic acid amplification can be directly added in the same tube for nucleic acid amplification at the next step. The process, operation periods and risks of contamination can be therefore reduced and a result of nucleic acid amplification with less background noises can be therefore obtained as well. | 2014-02-13 |
20140045221 | Oscillating Amplification Reaction for Nucleic Acids - One embodiment of the present invention provides for a method for amplifying a template of nucleic acid target sequence contained in a sample. The method includes contacting the sample with an amplification reaction mixture containing a primer complementary to the template of nucleic acid target sequence. A temperature of the reaction is oscillated between an upper temperature and a lower temperature wherein the change in temperature is no greater than about 20° C. during a plurality of temperature cycles. The template of nucleic acid target sequence is amplified. | 2014-02-13 |
20140045222 | BETA-AMYLASE, GENE CODING THEREFOR AND MANUFACTURING METHOD THEREOF - To provide novel β-amylase derived from a microorganism and a gene thereof. β-amylase derived from | 2014-02-13 |
20140045223 | Polypeptides Having Isoamylase Activity and Polynucleotides Encoding Same - The present invention relates to isolated polypeptides having isoamylase activity derived from | 2014-02-13 |
20140045224 | PROCESS FOR PRODUCING SACCHARIFIED SOLUTION - A process for producing a saccharified solution in an improved yield when filtering the mixture obtained by saccharifying lignocellulosic biomass is provided. A mixture containing a saccharified solution and an undecomposed biomass residue by treating a substrate biomass using a saccharification enzyme is obtained. The mixture is filtered to obtain the saccharified solution as a filtrate. Before filtering the mixture, 95% by mass or more of the particles, based on the total amount of particles contained in a centrifuged supernatant of the mixture, is adjusted to have a particle size ranging from 1 to 30 μm. | 2014-02-13 |
20140045225 | Proteins for the Treatment of Cellulosic Material - The present invention discloses novel polypeptides and enzyme preparations containing them, which enhance the efficiency of the cellulosic degradation even at elevated temperatures. The polypeptides are produced by recombinant technology, and means for their production are described. The novel polypeptides are useful in processing biomass, and in biofuel, starch, textile, detergent, pulp and paper, food, feed or beverage industries. They may also be used e.g. in cleaning the interior of a dishwashing machine or for biofinishing or biostoning. The novel polypeptides are also useful in animal feed. | 2014-02-13 |
20140045226 | PROCESS FOR TREATING LIGNOCELLULOSIC BIOMASS - A process for treating lignocellulosic biomass is described. The process includes treating particulate biomass with alkali to partially remove hemicellulose sheath on cellulose microfibrils of the biomass; and carrying out an oxidation reaction on the alkali treated biomass to form a treated biomass having a disrupted cellulose crystalline structure. The treated biomass may be further processed to form free sugars and lignin and the free sugars can be used to produce bio-ethanol or used as sugar source in fermentation processes. | 2014-02-13 |
20140045227 | EFFICIENT LIGNOCELLULOSE HYDROLYSIS WITH INTEGRATED ENZYME PRODUCTION - The present invention provides a process for degradation of lignocellulosic biomass, which has optionally been pre-treated. It is based on the finding that hydrolysis efficiency of the biomass is enhanced in the presence of a mechanically or chemically treated microorganism capable of producing the respective hydrolytic enzymes. The invention therefore provides a process for degradation of lignocellulosic biomass with integrated produced enzyme cocktails. The invention also provides a process wherein the part of the optionally pre-treated lignocellulosic biomass is incorporated into the final growth medium of the fungus. | 2014-02-13 |
20140045228 | Method for Producing L-Amino Acid - An L-amino acid is produced by culturing an Enterobacteriaceae which is able to produce an L-amino acid in a medium containing glycerol, especially crude glycerol, as the carbon source to produce and accumulate the L-amino acid in the culture, and collecting the L-amino acid from the culture. | 2014-02-13 |
20140045229 | TWO-STAGE PROCESS FOR PRODUCING OIL FROM MICROALGAE - A process for production of biofuels from algae can include cultivating an oil-producing algae by promoting sequential photoautotrophic and heterotrophic growth. The method can further include producing oil by heterotrophic growth of algae wherein the heterotrophic algae growth is achieved by introducing a sugar feed to the oil-producing algae. An algal oil can be extracted from the oil-producing algae, and can be converted to form biodiesel. | 2014-02-13 |
20140045230 | DICARBOXYLIC ACID PRODUCTION IN A FILAMENTOUS FUNGUS - The present invention relates to a recombinant fungus comprising an enzyme which catalysts the conversion of malic acid to fumaric acid in the cytosol. The invention further relates to a process for the production of a dicarboxylic acid such as fumaric acid and succinic acid, wherein the recombinant fungus is used. | 2014-02-13 |
20140045231 | METHODS FOR PRODUCING 3-HYDROXYPROPIONIC ACID AND OTHER PRODUCTS - This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product, which includes 3-hydroxypropionic acid. | 2014-02-13 |
20140045232 | ENZYME USED IN BIOSYNTHESIS OF 1, 4-BDO AND SCREENING METHOD OF THE SAME - Recombinant butyraldehyde dehydrogenases (Blds) with improved production of 1,4-BDO, as well as recombinant microorganisms comprising polynucleotides encoding the recombinant Blds, and methods of producing 1,4-BDO by using the recombinant microorganisms. | 2014-02-13 |
20140045233 | Method for Biotechnological Production of Dihydrochalcones - A method for production of a dihydrochalcone, especially of phloretin, using a transgenic microorganism, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a′), comprising or consisting of a gene coding for a plant chalcone isomerase, and a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, corresponding transgenic microorganisms, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a′), comprising or consisting of a gene coding for a plant chalcone isomerase, and/or a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, and host cells, containing one or more identical or different such vectors. | 2014-02-13 |
20140045234 | Applications of the rotating photobioreactor - A method to recover and harvest nutrients from a liquid stream by incorporating them into microorganisms grown in a rotating photobioreactor. The method further includes optionally integrating the rotating photobioreactor with a composting or biogenic drying process. | 2014-02-13 |
20140045235 | CONSTRUCTION OF A LACTOBACILLUS CASEI ETHANOLOGEN - An engineered bacterium for producing ethanol from one or more carbohydrates is disclosed. The bacterium can be made by (a) inactivating within a | 2014-02-13 |
20140045236 | METHOD AND SYSTEMS FOR ISOLATION AND/OR SEPARATION OF PRODUCTS FROM PRODUCTION PROCESSES - The present invention relates to separation of desired target products from biological, plant, and waste-type material, wherein the desired target products include renewable fuels such as ethanol, biobutanol, and biodiesel, wherein the separation is conducted with a cross-flow filtration system having the ability to separate desired products from both non-viscous and viscous medium. | 2014-02-13 |
20140045237 | USE OF VINASSE IN THE PROCESS OF SACCHARIFICATION OF LIGNOCELLULOSIC BIOMASS - The use of stillage in a saccharification/fermentation process of lignocellulosic biomasses, regardless of the form of the biomasses and regardless of the use of the obtained final hydrolyzed broth. The beneficial effect conferred by the stillage to the saccharification process of lignocellulosic biomasses presents among other characteristics the ability to buffer the reaction medium, especially when such process takes place in an enzymatic route, but not limited to it, regardless of the type of biomass being used and the type of pretreatment to which the biomass is subjected. Fermentation processes, such as the ethanol production, using stillage as source of nutrients such as, for example, nitrogen, for growing microorganisms, but not limited to it. | 2014-02-13 |
20140045238 | Method for producing terpenes - The present invention relates to a method for producing terpenes in fungi, wherein a terpene biosynthetic gene cluster having terpene biosynthetic genes and regulatory regions operably linked to said genes is activated. The invention relates also to a terpene biosynthetic gene cluster and regulatory regions of such terpene biosynthetic gene cluster usable is production of terpenes, use of regulator for regulating the terpene production and use of | 2014-02-13 |
20140045239 | RENEWABLE ENGINE FUEL AND METHOD OF PRODUCING SAME - The present invention provides high-octane fuel, and a method of producing same. These fuels may be formulated to have a wide range of octane values and energy, and may effectively be used to replace 100 LL aviation fuel (known as AvGas), as well as high-octane, rocket, diesel, turbine engine fuels, as well as two-cycle, spark-ignited engine fuels. | 2014-02-13 |
20140045240 | PROCESS FOR PREPARING METABOLIZED CONDITIONED GROWTH MEDIA - Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition. | 2014-02-13 |
20140045241 | MICELLAR POLYSILOXANE ENZYME IMMOBILIZATION MATERIALS - The present invention generally relates to immobilized enzymes for use in carbon capture and other systems; particularly, materials used to immobilize carbonic anhydrase are disclosed. | 2014-02-13 |
20140045242 | Novel Strategies for Improved Cancer Vaccines - The present invention concerns methods and compositions for forming anti-cancer vaccine complexes. In preferred embodiments, the anti-cancer vaccine complex comprises an antibody moiety that binds to dendritic cells, such as an anti-CD74 antibody or antigen-binding fragment thereof, attached to an AD (anchoring domain) moiety and a xenoantigen, such as CD20, attached to a DDD (dimerization and docking domain) moiety, wherein two copies of the DDD moiety form a dimer that binds to the AD moiety, resulting in the formation of the vaccine complex. The anti-cancer vaccine complex is capable of inducing an immune response against xenoantigen expressing cancer cells, such as CD138 | 2014-02-13 |
20140045243 | MUTANT CELLS FOR PROTEIN SECRETION AND LIGNOCELLULOSE DEGRADATION - The present disclosure provides mutant cells for the secretion of proteins and for the degradation of lignocellulosic biomass. Methods for the use of these cells are also provided. Specifically, the utility of combined genetic deletions of β-glucosidases and the catabolite repressor gene creA/cre-1 for protein secretion in fungal and yeast cells is disclosed. | 2014-02-13 |
20140045244 | REVERSE TRANSCRIPTASE HAVING IMPROVED THERMOSTABILITY - The present invention relates to a reverse transcriptase having improved thermostability, more precisely a mutant reverse transcriptase with improved thermostability by substitution of one or more amino acids selected from the group consisting of the 63 | 2014-02-13 |
20140045245 | REPLICATION DEFICIENT INFLUENZA VIRUS FOR THE EXPRESSION OF HETEROLOGOUS SEQUENCES - The present invention relates to a novel replication deficient influenza virus comprising a modified NS1 segment coding for a NS1 protein lacking a functional RNA binding domain and functional effector domain and having a heterologous sequence inserted between the splice donor site and the splice acceptor site of the NS gene segment. The virus can be used as vector for expression of various proteins like chemokines, cytokines or antigenic structures and to produce vaccines. A fusion peptide comprising part of the N-terminus of an NS1 protein and a signal sequence fused to the C-terminus of said NS1 peptide is also provided. | 2014-02-13 |
20140045246 | PROCESS FOR FERMENTATION OF SYNGAS - A process for fermenting syngas is provided which is effective for decreasing an amount of time needed to inoculate a main reactor. The process includes propagating a culture of acetogenic bacteria to provide an incoulum for a main reactor and fermenting syngas in the main reactor. | 2014-02-13 |
20140045247 | FUSION PROTEIN - The present invention provides means useful for making devices, materials and the like that are excellent in photocatalytic activity, electric property or the like. Specifically, the present invention provides a fusion protein comprising a polypeptide portion capable of forming a multimer having an internal cavity, and a first peptide portion capable of binding to a first target substance and a second peptide portion capable of binding to a second target substance; a multimer of the fusion protein; a complex comprising the multimer of the fusion protein; and the like. | 2014-02-13 |
20140045248 | SYSTEM FOR REMOVING SELENIUM FROM A FEED STREAM - A system for removing selenium from a solid feed stream includes a selenium dissolver configured to selectively dissolve elemental selenium from the solid feed stream and to produce a selenium rich solution and a crystallizer coupled to the selenium dissolver and configured to receive the selenium rich solution from the dissolver, to add an acid to the selenium rich solution, to remove purified selenium from the selenium rich solution, and to remove sulfur dioxide from the selenium rich solution. | 2014-02-13 |
20140045249 | CENTRIFUGAL PARTICLE SEPARATION AND DETECTION DEVICE - The present invention provides a centrifugal particle separation and detection device, which can separate and detect particles according to the particle size. The centrifugal particle separate and detection device is practiced with a centrifuge to separate particles, and can be applied to cancer cell detection, blood lymphocyte isolation, tissue engineering, polynucleotide hybridization, microorganism separation and detection and fine chemical purification. | 2014-02-13 |
20140045250 | REAL-TIME OPTICAL SYSTEM FOR POLYMERASE CHAIN REACTION - An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate reduced sample read time and rapid reading of multiple light wavelengths. | 2014-02-13 |
20140045251 | SEQUENTIAL ANALYSIS OF BIOLOGICAL SAMPLES - Methods for detecting multiple targets in a biological sample are provided. The methods includes contacting the sample with a first probe; physically binding the first probe to a first target; observing a first signal from the first probe; applying a chemical agent to modify the first signal; contacting the sample with a second probe; physically binding the second probe to a second target; and observing a second signal from the second probe. The methods disclosed herein also provide for multiple iterations of binding, observing, signal modification for deriving information about multiple targets in a single sample. An associated kit and device are also provided. | 2014-02-13 |
20140045252 | CELL CULTIVATION CONTAINER AND CELL CULTURING APPARATUS - Provided is a cell cultivation container equipped with electrodes, which enables automatic culturing, observation of automatically cultured cells, and measurement of electrical resistances. A circular electrode ( | 2014-02-13 |
20140045253 | MULTI-COMPARTMENT DEVICE FOR CELL CLONING AND METHOD OF PERFORMING THE SAME - The problems associated with the traditional methods and devices in the field of cell cloning have been solved by the multi-compartment device and method in the present invention. The device combines the advantages of a traditional petri-dish and a traditional microplate. The multi-compartment device in the present invention comprises sidewalls, which are taller than openings of the multi-compartments. The cells in the suspension flow across the multi-compartments and seed inside the compartments during a plating process. The multi-compartment device in the present invention allows easier plating process, changing conditioned medium, and cell colony detachment and transfer. The multi-compartment device also minimizes the risk of cross-contamination during cloning process and during cell colony transfer. The invention also provides an exemplary method of using the multi-compartment device for cell cloning. In one aspect of the method, the multi-compartment device may be tilted before or after adding the cell suspension during plating process. | 2014-02-13 |
20140045254 | CELL SELF-ASSEMBLY ARRAY CHIP AND MANUFACTURING METHOD THEREOF - A cell self-assembly array chip comprises a first substrate, a second substrate and a plurality of spacer elements. The first substrate, the spacer elements and the second substrate are stacked to be one in turn, wherein the spacer elements are annularly arranged at interval and disposed on the second substrate, so as to define a cell self-assembly region and at least one drawing channel. Furthermore, because the liquid portion of cell suspension horizontally and radially passed the drawing channel outward and the radially outward pulling force generated by the evaporation effect of the liquid portion, so as to cause the cells are arranged by the cell self-assembly array to the cell self-assembly region. The present invention further provides a manufacturing method of a cell self-assembly array chip to solve the conventional problems which is difficult to culture living cells and not easy to apply optical observation. | 2014-02-13 |
20140045255 | THERMAL CYCLER AND THERMAL CYCLING METHOD - A thermal cycler includes a holder to which a biotip having a longitudinal direction is attached in such a manner that one end portion of the biotip is at a higher level than the other end portion, and that the distance between one end portion of the biotip and the rotational axis is shorter than the distance between the other end portion of the biotip and the rotational axis, a heating unit heats a first end portion of the biotip, a rotating unit rotates the holder, and a controller that controls the rotation speed of the rotating unit. The controller has a first mode a rotation speed at which the magnitude of the centrifugal force acting on the reaction mixture becomes smaller than the gravity, and a second mode a rotation speed at which the magnitude of the centrifugal force acting on the reaction mixture becomes greater than the gravity. | 2014-02-13 |
20140045256 | CELL CHIP - There is provided a cell chip including: a first substrate having biomaterials fixed thereto; a second substrate provided with one or more receiving space in which a culture medium is stored; and a circulation unit circulating the culture medium stored in the receiving space. | 2014-02-13 |
20140045257 | METHODS FOR SEQUESTERING CARBON DIOXIDE INTO ALCOHOLS VIA GASIFICATION FERMENTATION - The present invention is directed to improvements in gasification for use with synthesis gas fermentation. Further, the present invention is directed to improvements in gasification for the production of alcohols from a gaseous substrate containing at least one reducing gas containing at least one microorganism. | 2014-02-13 |
20140045258 | HUMAN MICRORNAS AND METHODS FOR INHIBITING SAME - The invention relates to isolated DNA or RNA molecules comprising at least ten contiguous bases having a sequence in a microRNA shown in SEQ ID NOs: 1-94; 281-374; 467-481; 497-522; or 549, except that up to thirty percent of the bases may be wobble bases, and up to 10% of the contiguous bases may be non-complementary. The invention further relates to modified single stranded microRNA molecules, isolated single stranded anti-microRNA molecules and isolated microRNP molecules. In another embodiment, the invention relates to a method for inhibiting microRNP activity in a cell. | 2014-02-13 |
20140045259 | Suppressor tRNA Transcription in Vertebrate Cells - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA's/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided. | 2014-02-13 |
20140045260 | METHODS AND COMPOSITIONS FOR PROMOTING SURVIVAL AND PROLIFERATION OF ENDOTHELIAL CELLS AND STIMULATING ANGIOGENESIS - The present invention relates to adenovirus E4ORF1 gene and to endothelial cells engineered to express the E4ORF1 gene. The present invention also relates to uses of the E4ORF1 gene, and cells expressing the E4ORF1 gene, and to compositions comprising the E4ORF1 gene, or comprising cells expressing the E4ORF1 gene. | 2014-02-13 |
20140045261 | SITE-SPECIFIC INCORPORATION OF AMINO ACIDS INTO MOLECULES - The invention provides certain embodiments relating to methods and compositions for incorporating non-natural amino acids into a polypeptide or protein by utilizing a mutant or modified aminoacyl-tRNA synthetase to charge the non-natural amino acid to a the corresponding tRNA. In certain embodiments, the tRNA is also modified such that the complex forms strict Watson-Crick base-pairing with a codon that normally forms wobble base-pairing with unmodified tRNA/aminoacyl-tRNA synthetase pairs. | 2014-02-13 |
20140045262 | CONSTRUCTS AND METHOD FOR REGULATING GENE EXPRESSION OR FOR DETECTING AND CONTROLLING A DNA LOCUS IN EUKARYOTES - The present invention concerns constructs based on sequences derived from the partitioning system of plasmid and chromosomal DNA of bacteria, such as eukaryotic expression vectors, fusion proteins and polynucleotides encoding the same and also eukaryotic cells transformed with or expressing such constructs. The present invention also concerns the use thereof in the regulation of gene expression and/or in the detection and control of the dynamics, localization or metabolism of genomic DNA loci of interest in eukaryotic cells. | 2014-02-13 |
20140045263 | POSTPARTUM CELLS DERIVED FROM UMBILICAL CORD TISSUE, AND METHODS OF MAKING AND USING THE SAME - Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described. | 2014-02-13 |
20140045264 | METHOD OF CRYOPRESERVATION OF STEM CELL-DERIVED RETINAL PIGMENT EPITHELIAL CELLS ON POLYMERIC SUBSTRATE - Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease. | 2014-02-13 |
20140045265 | ROBUST AND EFFICIENT DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS TO MULTIPOTENT VASCULAR PROGENITORS - Provided herein are methods and compositions for generating vascular progenitor cells that can in turn be differentiated into endothelial, smooth muscle, and hematopoietic cells. The present methods provide a faster, safer, and more efficient in vitro differentiation program than existing methodologies. The differentiated cells can be used for research and therapeutic applications, such as cell transplantation. | 2014-02-13 |
20140045266 | METHODS OF CULTURING CELLS IN A MEDIUM COMPRISING TRANSFORMING GROWTH FACTOR BETA 1 AND BASIC FIBROBLAST GROWTH FACTOR - The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells. | 2014-02-13 |
20140045267 | Methods of Introducing Nucleic Acids into Cellular DNA - A method of introducing a nucleic acid sequence into a cell is provided where the cell has impaired or inhibited or disrupted primase activity or impaired or inhibited or disrupted helicase activity, or larger or increased gaps or distance between Okazaki fragments or lowered or reduced frequency of Okazaki fragment initiation, or the cell has increased single stranded DNA (ssDNA) on the lagging strand of the replication fork including transforming the cell through recombination with a nucleic acid oligomer. | 2014-02-13 |
20140045268 | Proteases With Modified Pro Regions - The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include modified polynucleotides that encode modified proteases, which have at least one mutation in the pro region; the modified serine proteases encoded by the modified polynucleotides; expression cassettes, DNA constructs, and vectors comprising the modified polynucleotides that encode the modified proteases; and the bacterial host cells transformed with the vectors of the invention. The methods include methods for enhancing the production of mature proteases in bacterial host cells e.g. | 2014-02-13 |
20140045269 | COBALT-MOLYBDENUM SULFIDE CATALYST MATERIALS AND METHODS FOR STABLE ALCOHOL PRODUCTION FROM SYNGAS - The present invention provides methods and compositions for the chemical conversion of syngas to alcohols. The invention includes catalyst compositions, methods of making the catalysts, and methods of using the catalysts including techniques to maintain catalyst stability. Certain embodiments teach compositions for catalyzing the conversion of syngas into products comprising at least one C | 2014-02-13 |
20140045270 | DEVICE HAVING NANOPORE WITH THIOL-CONTAINING MATERIAL ATTACHED TO GOLD LAYER AND METHOD OF ANALYZING NUCLEIC ACID USING THE DEVICE - Provided is a device with a nanopore that has a thiol-containing material bound to a gold layer, methods of producing the devices, and methods of analyzing nucleic acid using the devices. | 2014-02-13 |
20140045271 | Potentiometric Titration Method for Measuring Concentration of Acid Mixture of Aluminum Etchant - The present invention provides a potentiometric titration method for measuring concentration of acid mixture of aluminum etchant, which prepares identified potassium hydroxide-ethanol solution or sodium hydroxide-ethanol solution as a titrant and uses a monohydric alcohol and a diol as an anhydrous medium for the acid mixture of aluminum etchant to carry out titration of the acid mixture of aluminum etchant so as to realize measurement of concentration of each acid contained in the acid mixture of aluminum etchant through a one-stage process of potentiometric titration thereby reducing the complication of operation of inspection and uncertainty of inspection result and achieving the purposes of carrying out inspections with high precision and high performance. The method can efficiently and accurately measure the concentrations of nitric acid, phosphoric acid, and acetic acid contained in the acid mixture of aluminum etchant. | 2014-02-13 |
20140045272 | MEASURING DEVICE FOR MEASURING SINGLET OXYGEN LUMINESCENCE - A measuring device measures singlet oxygen luminescence which is excited by one or more photosensitizers. The measuring device contains a photosensitive detector, an excitation source, and a control and evaluating unit that is coupled to the photosensitive detector and the excitation source. The excitation source is configured to radiate excitation light into a measurement volume from a plurality of emission positions in order to excite the photosensitizer or photosensitizers. The excitation source preferably contains light-emitting diodes as lighting devices, the light of which is used directly as an excitation light in order to excite the photosensitizers. | 2014-02-13 |
20140045273 | METHODS AND APPARATUS FOR IDENTIFICATION OF POLYMERIC SPECIES FROM MASS SPECTROMETRY OUTPUT - Methods and apparatus are provided for the identification of one or more candidate chemical formulas from mass spectrometry data corresponding to an unidentified chemical compound. By restricting the generation of candidate formulas to those having repeating units and/or end units with specified limitations, the methods and apparatus may more efficiently iteratively search for a chemical formula having matching mass spectrometry output within a threshold tolerance. In another aspect, methods and apparatus are provided for the identification of one or more candidate chemical formulas from mass spectrometry data based at least in part upon neutral loss. | 2014-02-13 |
20140045274 | Method for Harvesting Nanoparticles and Sequestering Biomarkers - Capture particles for harvesting analytes from solution and methods for using them are described. The capture particles are made up of a polymeric matrix having pore size that allows for the analytes to enter the capture particles. The pore size of the capture particles are changeable upon application of a stimulus to the particles, allowing the pore size of the particles to be changed so that analytes of interest remain sequestered inside the particles. The polymeric matrix of the capture particles are made of co-polymeric materials having a structural monomer and an affinity monomer, the affinity monomer having properties that attract the analyte to the capture particle. The capture particles may be used to isolate and identify analytes present in a mixture. They may also be used to protect analytes which are typically subject to degradation upon harvesting and to concentrate low an analyte in low abundance in a fluid. | 2014-02-13 |
20140045275 | APPARATUS FOR HERMETICALLY SEALED STORAGE OF LIQUIDS FOR A MICROFLUIDIC SYSTEM - An apparatus for hermetically sealed storage of liquids for a microfluidic system includes at least one cavity and at least one sealing cone through which a connection to the microfluidic system is configured to be established and which closes the cavity. | 2014-02-13 |
20140045276 | ASSAYS FOR DETECTING AUTOANTIBODIES TO ANTI-TNFALPHA DRUGS - The present invention provides assays for detecting and measuring the presence or level of autoantibodies to anti-TNFα drug therapeutics in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNFα drug therapeutics to detect the presence or level of autoantibodies against the drug. The present invention also provides methods for selecting therapy, optimizing therapy, and/or reducing toxicity in subjects receiving anti-TNFα drugs for the treatment of TNFα-mediated disease or disorders. | 2014-02-13 |
20140045277 | SYSTEM FOR TRAPPING, INTERACTING AND MODIFYING SINGLE PROTEIN MOLECULES USING A DOUBLE-NANOHOLE STRUCTURE - Molecules or particle having a hydrodynamic radius as small as 3.5 nm can be trapped using a double-nanohole structure defined in a metal film or other metallic layer. Application of a suitable optical radiation flux to the double-nanohole structure can provide a folding and/or binding of protein molecules that can be identified based on changes in optical transmission. Varying nanohole transmissions can thus be associated with trapping, binding and unfolding of biological particles. The double-nanohole defines cusps, but such cusps can be defined in other ways as well. | 2014-02-13 |
20140045278 | Method of Manufacturing Semiconductor Device, Method of Processing Substrate and Substrate Processing Apparatus - A method of manufacturing a semiconductor device includes: (a) supplying a first process gas from a first process gas supply unit into a process chamber via a flow rate control device to form a film on a substrate; (b) transmitting a signal representing an exhaust pressure detected by a pressure detector to a controller after the first process gas is supplied into the process chamber; (c) controlling a pressure adjustor and the flow rate control device once the signal is received by the controller such that the exhaust pressure reaches a predetermined pressure; (d) supplying a purge gas from a purge gas supply unit into the process chamber to purge an inside atmosphere after forming the first film; and (e) supplying a second process gas from a second process gas supply unit into the process chamber via the flow rate control device to form a second film. | 2014-02-13 |
20140045279 | Semiconductor Component and Method for Producing a Semiconductor Component - A method can be used to produce a semiconductor component. A semiconductor layer sequence has an active region that is provided for generating radiation and also has an indicator layer. Material of the semiconductor layer sequence that is arranged on that side of the indicator layer that is remote from the active region is removed in regions. The material is removed using a dry-chemical removal of the semiconductor layer sequence. A property of a process gas is monitored during the removal to determine that the indicator layer has been reached based on a change in the property of the process gas. | 2014-02-13 |
20140045280 | METHOD FOR PACKAGING CIRCUITS - A method for packaging integrated circuit chips (die) is described that includes providing a base substrate with package level contacts, coating a base substrate with adhesive, placing dies on the adhesive, electrically connecting the die to the package level contacts, and removing the backside of the base substrate to expose the backside of the package level contacts. Accordingly, an essentially true chip scale package is formed. Multi-chip modules are formed by filling gaps between the chips with an encapsulant. In an embodiment, chips are interconnected by electrical connections between package level contacts in the base substrate. In an embodiment, substrates each having chips are adhered back-to-back with through vias formed in aligned saw streets to interconnect the back-to-back chip assembly. | 2014-02-13 |
20140045281 | SUBSTRATE PROCESSING APPARATUS AND SUBSTRATE PROCESSING METHOD - Provided is a substrate processing apparatus in which flexibility of disposing a device configured to determine a holding state of a substrate and the flexibility of timing of determining the holding state are enhanced. The substrate processing apparatus includes a light projector configured to radiate detection light toward a region where a substrate may exist when the substrate is held by a substrate holding member and a light receiver configured to receive the detection light radiated from the light projector. A light path of the detection light from the light projector toward the light receiver passes a substrate surrounding member installed around the substrate held by the substrate holding member. The detection light penetrates the substrate surrounding member and has a wavelength which does not penetrate the substrate. | 2014-02-13 |
20140045282 | Using Spectra to Determine Polishing Endpoints - Methods of determining a polishing endpoint are described using spectra obtained during a polishing sequence. In particular, techniques for using only desired spectra, faster searching methods and more robust rate determination methods are described. | 2014-02-13 |
20140045283 | Method for Manufacturing Light-Emitting Device - To provide a method for manufacturing a lightweight light-emitting device having a light-emitting region on a curved surface. The light-emitting region is provided on a curved surface in such a manner that a light-emitting element is formed on a flexible substrate supported in a plate-like shape and the flexible substrate deforms or returns. | 2014-02-13 |
20140045284 | SEMICONDUCTOR BUFFER STRUCTURE, SEMICONDUCTOR DEVICE INCLUDING THE SAME, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING SEMICONDUCTOR BUFFER STRUCTURE - A method of manufacturing a semiconductor device includes forming a silicon substrate, forming a buffer layer on the silicon substrate, and forming a nitride semiconductor layer on the buffer layer. The buffer layer includes a first layer, a second layer, and a third layer. The first layer includes Al | 2014-02-13 |
20140045285 | PARALLEL PLATE SLOT EMISSION ARRAY - In accordance with an embodiment of the present invention, an article of manufacture includes a side-emitting light emitting diode configured to emit light from more than two surfaces. The article of manufacture includes a first sheet electrically and thermally coupled to a first side of the light emitting diode, and a second sheet electrically and thermally coupled to a second side of the light emitting diode. The article of manufacture further includes a plurality of reflective surfaces configured to reflect light from all of the surfaces of the light emitting diode through holes in the first sheet. The light may be reflected via total internal reflection. | 2014-02-13 |
20140045286 | LIGHT EMITTING DEVICE PACKAGE AND METHOD OF MANUFACTURING THE SAME - Provided is a light emitting device package including: a plurality of lead frames disposed to be separated from one another; at least one light emitting device mounted on the lead frames and electrically connected to the lead frames through a bonding wire provided on a wire bonding pad, the wire bonding pad being disposed on the same surface as a light emission surface provided as an upper surface of the light emitting device; a body part formed to encapsulate and support the wire bonding pad, the bonding wire, the light emitting device and the lead frames, and having a reflective groove formed in an upper surface thereof to expose the light emission surface to the outside therethrough; and a lens part disposed on the body part, to cover the light emitting device. | 2014-02-13 |
20140045287 | METHOD FOR MANUFACTURING DISPLAY DEVICE, METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE - A method of manufacturing liquid crystal display devices according to the present invention includes: forming a protective film on a first base substrate; forming a circuit element part on the first base substrate and/or the protective film; bonding a second base substrate to the first base substrate to form bonded substrates including both substrates, the circuit element part being therebetween; forming a first incision on a outer surface of the first base substrate on which the protective film is formed, at a location overlapping with the protective film; wet-etching the formed first incision to make the incision deeper; forming a second incision on an outer surface of the second base substrate at a location overlapping the first incision, and dividing the bonded substrates along the first incision and the second incision, thereby forming a plurality of individual bonded substrates. | 2014-02-13 |
20140045288 | METHOD OF MANUFACTURING SEMICONDUCTOR LIGHT EMITTING DEVICE - A method of manufacturing a semiconductor light emitting device includes preparing a light emitting structure including first and second conductivity type semiconductor layers and an active layer interposed therebetween, forming a plurality of seeds on at least one surface of the light emitting structure, and forming a plurality of dome-shaped protrusions by forming optical waveguide groups from the plurality of respective seeds and combining the optical waveguide groups. | 2014-02-13 |
20140045289 | METHOD FOR MANUFACTURING NITRIDE SEMICONDUCTOR LAYER AND METHOD FOR MANUFACTURING SEMICONDUCTOR LIGHT EMITTING DEVICE - According to one embodiment, a method is disclosed for manufacturing a nitride semiconductor layer. The method can include forming a first nitride semiconductor layer on a substrate in a reactor supplied with a first carrier gas and a first source gas. The first nitride semiconductor layer includes indium. The first carrier gas includes hydrogen supplied into the reactor at a first flow rate and includes nitrogen supplied into the reactor at a second flow rate. The first source gas includes indium and nitrogen and supplied into the reactor at a third flow rate. The first flow rate is not less than 0.07% and not more than 0.15% of a sum of the first flow rate, the second flow rate, and the third flow rate. | 2014-02-13 |
20140045290 | METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING MICROPHONE - A method for manufacturing a semiconductor device is provided, the method comprising: fabricating a semiconductor element on a semiconductor substrate; joining a surface of the semiconductor substrate to a support member, the surface being on a side where the semiconductor element is fabricated; and polishing a surface on an opposite side of the surface of the semiconductor substrate where the semiconductor element is fabricated and reducing a thickness of the semiconductor substrate, in a state where the semiconductor substrate and the support member are joined. | 2014-02-13 |
20140045291 | SOLID-STATE IMAGE PICK-UP DEVICE AND MANUFACTURING METHOD THEREOF, IMAGE-PICKUP APPARATUS, SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF, AND SEMICONDUCTOR SUBSTRATE - A solid-state image pick-up device is provided which includes a semiconductor substrate main body which has an element forming layer and a gettering layer provided on an upper layer thereof; photoelectric conversion elements, each of which includes a first conductive type region, provided in the element forming layer; and a dielectric film which is provided on an upper layer of the gettering layer and which induces a second conductive type region in a surface of the gettering layer. | 2014-02-13 |
20140045292 | METHOD OF MANUFACTURING IMAGE PICKUP DEVICE - A method of manufacturing an image pickup device includes a step of forming a filling member such that the filling member covers a light guiding part and a peripheral part provided in a film. The light guiding part is positioned on an image pickup region of the image pickup device and has openings that correspond to respective photoelectric conversion portions. The peripheral part is positioned on a peripheral region of the image pickup device. The filling member fills in the openings. The method includes a step of processing the filling member. The method includes a step of forming light guiding members, which is performed after the step of processing filling member has been performed, by a polishing process performed on the filling member so that the light guiding part is exposed. The light guiding members are part of the filling member and disposed in the openings. | 2014-02-13 |
20140045293 | FABRICATION OF INTERCONNECTED THIN-FILM CONCENTRATOR CELLS USING SHADOW MASKS - A method for fabricating thin film solar cells for a concentrated photovoltaic system uses three shadow masks. The first mask, used to deposit a back contact layer, has multiple horizontal and vertical lines defining columns and rows of cells, and multiple tabs each located in a cell along a center of a vertical border. The second mask, used to deposit a CIGS absorption layer, a window layer and a transparent contact layer, is similar to the first mask except the tabs are located along the opposite vertical border of the cells. The third mask, used to deposit a metal grid layer, has multiple bus bar openings and finger openings. Each bus bar opening is located along a horizontal center line of a cell and overlaps the second tab of a neighboring cell. The cells in a horizontal row are connected in series, forming a linear solar receiver. | 2014-02-13 |
20140045294 | MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE - A substrate includes a first region having photoelectric conversion portions and a second region having an element included in a signal processing circuit. An insulator including first and second parts respectively arranged on the first and second regions is formed on the substrate. Openings are formed in the insulator and respectively superposed on the photoelectric conversion portions. A first member is formed in the openings and on the second part of the insulator after forming the openings. At least a portion of the first member arranged on the second region is removed. The first member is planarized after removing at least the portion of the first member. A second insulator is formed on the first and second regions after planarizing the first member. A through-hole is formed in a part of the second insulator. No planarization with grinding is performed after forming the second insulator and before forming the through-hole. | 2014-02-13 |
20140045295 | PLASMA ANNEALING OF THIN FILM SOLAR CELLS - Embodiments relate to a method for annealing a solar cell structure including forming an absorber layer on a molybdenum (Mo) layer of a solar cell base structure. The solar cell base structure includes a substrate and the Mo layer is located on the substrate. The absorber layer includes a semiconductor chalcogenide material. Annealing the solar cell base structure is performed by exposing an outer layer of the solar cell base structure to a plasma. | 2014-02-13 |
20140045296 | High Voltage Opto-Electric Switch - Improvements for optically activated electric switches are considered. Techniques are presented for reducing the peaking of the electric field at edge of the contacts. For the body of the opto-switch, methods are described to increase the number of traps. Improvements in illumination are also discussed. | 2014-02-13 |