07th week of 2014 patent applcation highlights part 36 |
Patent application number | Title | Published |
20140044596 | HYDROGEN PEROXIDE DISINFECTANT CONTAINING A CYCLIC CARBOXYLIC ACID AND/OR AROMATIC ALCOHOL - An aqueous disinfecting solution, a concentrated version of the solution, and a dry powdered composition which may be dissolved in water to provide the solution. The solution has a pH of from 0.6 to 7 and comprises (a) hydrogen peroxide in a concentration of from 0.01 to 6% w/w; and (b) at least one component chosen from cyclic carboxylic acids and aromatic alcohols, in a concentration of from 0.01 to 10% w/w, all based on the total weight of the solution. The cyclic carboxylic acids are preferably 2-furan carboxylic acid, benzoic acid and salicylic acid and the aromatic alcohol is preferably benzyl alcohol. Furthermore, the solution may contain surfactants, corrosion inhibitors, hydrotropes, cation sequestering agents, hydrogen peroxide stabilizers, solvents, thickeners, skin conditioning agents, antifoams, and pH buffers. | 2014-02-13 |
20140044597 | DEVICE FOR TRANSPORTING A HOLLOW BODY, INSTALLATION PROVIDED WITH SUCH DEVICES, AND METHOD FOR CONVEYING A HOLLOW BODY ATTACHED TO SUCH A DEVICE - The invention concerns a device, an installation and a method for conveying a hollow body secured to a transport device, comprising a step of injection of a disinfecting fluid through at least one bore designed to pass through said transport device and opening into the inner volume of the hollow body secured to said transport device. | 2014-02-13 |
20140044598 | HIGH-PRESSURE, HIGH-TEMPERATURE MAGIC ANGLE SPINNING NUCLEAR MAGNETIC RESONANCE DEVICES AND PROCESSES FOR MAKING AND USING SAME - Re-usable ceramic magic angle spinning (MAS) NMR rotors constructed of high-mechanic strength ceramics are detailed that include a sample compartment that maintains high pressures up to at least about 200 atmospheres (atm) and high temperatures up to about least about 300° C. during operation. The rotor designs minimize pressure losses stemming from penetration over an extended period of time. The present invention makes possible a variety of in-situ high pressure, high temperature MAS NMR experiments not previously achieved in the prior art. | 2014-02-13 |
20140044599 | SYSTEMS AND METHODS FOR MONITORING AND COMPENSATING FOR BLEACH CONCENTRATION CHANGES - Systems and methods for monitoring and compensating for bleach concentration changes within a disinfection system may be provided. A bleach concentration monitor may be introduced into a disinfection system to measure the percentage concentration of a bleach precursor that may be introduced into a mixer and then report the measurements to pump controls within the disinfection system. Data relating measurements of the concentration of the bleach precursor may be transmitted to pump controls within the disinfection system so that adjustments may be made to a control algorithm within the pump controls to compensate for any changes that may be observed related to bleach concentration in the system. | 2014-02-13 |
20140044600 | DEVICE FOR TREATING CHEMICAL COMPOSITIONS AND METHODS FOR USE THEREOF - Devices for treating chemical compositions of a sample and methods for use thereof are disclosed here. In one embodiment, for example, a device may include a container; an opening; a magnetic component that induces a magnetic field across a portion of the device; and a sorptive media loaded within the container. The device may further comprise a magnetizable fluid loaded within the container. The sorptive media may be configured to filter a composition from a magnetizable fluid. The magnetic field may be configured to drive filtration of the magnetizable fluid containing composition after reacting the composition in order to remove or separate constituents of the composition. | 2014-02-13 |
20140044601 | PROCESS FOR THE PURIFICATION OF CRUDE GAS FROM SOLIDS GASIFICATION - A process and device is provided for the generation and purification of a crude gas for synthesis gas generation from a solid carbon-containing fuel by a coal gasification reaction. The fuel is mixed with a quenching medium directly after generation to dissipate the internal energy and is then brought into contact with a compound or a sorbent in the mixing chamber or downstream of the mixing chamber such that the acidic or basic or sulphur-containing or halogen-containing constituents contained in the crude gas and originating from the gasification reaction are absorbed. A solids-separating device removes the solid or solidified constituents from the system. The sorbent can be regenerated and returned to the process such that an energy-intensive cooling of the crude gas is not required for its purification and the synthesis gas thus purified can be used in a subsequent process without any further heating. | 2014-02-13 |
20140044602 | BIOMASS FEED SYSTEM INCLUDING GAS ASSIST - An improved biomass feed system and processes for transporting biomass to downstream processing locations are disclosed. The system uses a pressurized gas to assist in the transporting of the biomass to the conversion reactor. | 2014-02-13 |
20140044603 | DEVICE FOR GENERATING AMMONIA - An exhaust line of a motor vehicle includes an upstream monolith and a downstream monolith for treating exhaust gases passing along the exhaust line. The upstream and downstream monoliths are positioned in series. | 2014-02-13 |
20140044604 | ELECTROCHEMICAL CARBON MONOXIDE PRODUCTION - A method and apparatus for producing a carbon monoxide containing product in which cathode and anode sides of an electrically driven oxygen separation device are contacted with carbon dioxide and a reducing agent, respectively. The carbon dioxide is reduced to carbon monoxide through ionization of oxygen and the reducing agent lowers the partial pressure of oxygen at the anode side to partially drive oxygen ion transport within the device through the consumption of the oxygen and to supply heat. The lowering of oxygen partial pressure reduces voltage and therefore, electrical power required to be applied to the device and the heat is supplied to heat the device to an operational temperature and to the reduction of the carbon dioxide occurring at the cathode side. The device can be used as part of an integrated apparatus in which the carbon dioxide is supplied from a waste stream of a process plant. | 2014-02-13 |
20140044605 | Fuel Unit, Refillable Hydrogen Generator And Fuel Cell System - A packaged fuel unit and a refillable hydrogen generator that uses the fuel unit to produce hydrogen gas are disclosed. The fuel unit includes a reactant that can undergo a thermal decomposition reaction that produces hydrogen gas when heated to at least a minimum initiation temperature. The reactant is contained within a package that includes a poor thermal conductor with one or more thermal conductor sections for conducting heat from outside the package to the reactant. The hydrogen generator includes a holder with a cavity in which the fuel unit can be removably disposed and a heating system for heating the fuel unit when disposed therein. The hydrogen generator can be part of a fuel cell system including a fuel cell battery that is provided with hydrogen gas from the hydrogen generator. | 2014-02-13 |
20140044606 | FLEXIBLE LINE SEGMENT FOR THE EXHAUST SYSTEM OF AN INTERNAL COMBUSTION ENGINE - A flexible line segment for the exhaust system of an internal combustion engine, with an annularly corrugated or helically corrugated metallic bellows, for exhaust gas flow therethrough, and a line segment arranged upstream in reference to the metallic bellows, with a precipitation device provided in the line section, arranged upstream in reference to the metallic bellows or mounted thereat. The precipitation device is provided for urea derivatives or urea entrained in an edge layer of the exhaust gas flow from an oversaturated edge layer of the exhaust gas flow. | 2014-02-13 |
20140044607 | SEAL DEVICE WITH COMPENSATION CAPACITY FOR A PLURALITY OF MOVEMENT DIRECTIONS - A seal device is provided for sealing intermediate spaces formed between bodies arranged to be relatively movable, wherein the seal device has a resilient, gas-tight main body which is extendable in a peripheral direction and through which a portion of the first of the two bodies is guided, and a first end portion, which fastenable to the second body, and a second end portion, which is settable against the first movable body, wherein the second end portion is movable with respect to the first end portion in a first transverse direction which extends at an angle different from 0° with respect to a longitudinal direction. A sliding seal device, which is applicable to the first movable body so that a relative rotation is made possible between the first body and the second body by a pre-set angle, is arranged on the second end portion of the seal device. | 2014-02-13 |
20140044608 | Analytical Aid - A process for producing an analytical aid for the detection of at least one analyte in a sample, such as a body fluid. The analytical aid includes at least one housing and at least one test element including at least one test chemistry. The process includes the following steps: providing the test element; and producing at least one housing part of the housing at least one shaping process, during which the test element is connected to the housing part. | 2014-02-13 |
20140044609 | DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE - A dual-function heat indicator for monitoring two or more modes of heat exposure is described. A manufacturing process for the dual-function heat indicator is also described. Dual-function heat indicators as described may be useful for monitoring the exposure of host products, with which the dual-function heat indicators may be associated, to cumulative ambient heat exposure and to a peak ambient heat exposure, and for other purposes. | 2014-02-13 |
20140044610 | MICROFLUIDIC DEVICE - The present invention provides a microfluidic device which is molded with a die and has a specimen inlet part. The microfluidic device has the specimen inlet part. The specimen inlet part has an inlet channel for introducing a specimen into the flow channel, wherein the inlet channel has a diameter which continuously and gradually increases as the inlet channel approaches the flow channel, or has a diameter which is constant in the vicinity of an inlet port and then continuously and gradually increases as the inlet channel approaches the flow channel. | 2014-02-13 |
20140044611 | REAGENT CONTAINER - This reagent container comprises a container body for storing a liquid reagent employed for an analyzer and a band-like grasp portion mounted on the container body so that the user grasps the container body in a suspended state, and the grasp portion includes a band-like member whose first and second end sides are mounted on the container body and a protective member provided on the band-like member to project from an edge portion of the band-like member. | 2014-02-13 |
20140044612 | After-Treatment System - An after-treatment system includes a Selective Catalytic Reduction (SCR) catalyst or a similar aftertreatment unit or brick that may be inserted into the opened end of a sleeve. The aftertreatment brick includes a substrate matrix with catalytic material that extends between a first face and a second face. A mantle is disposed around the substrate matrix and extends between a first rim proximate the first face and a second rim proximate the second face. The mantel may include a overhang extension that extends the first rim of the mantle beyond the first face of the substrate matrix. To enable retrieval of the SCR catalyst from the sleeve, a retrieval feature is disposed on a readily accessible, inner surface of the overhang extension. | 2014-02-13 |
20140044613 | CATALYTIC ISOBUTANE ALKYLATION - A novel catalytic reactor is provided for controlling the contact of a limiting reactant with a catalyst surface. A first flow vessel defines an interior surface and an exterior surface, and the interior surface has a catalyst deposited on at least a portion thereof. A second flow vessel is positioned within the first flow vessel and the second flow vessel defines a porous surface designed to deliver a fluid uniformly to at least a portion of the interior surface of the first flow vessel. | 2014-02-13 |
20140044614 | REACTOR SYSTEM FOR PRODUCING HYDROCARBONS FROM SYNTHETIC GAS - The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst. | 2014-02-13 |
20140044615 | METHOD AND SYSTEM FOR EXTRACTION OF URANIUM USING AN ION-EXCHANGE RESIN - The invention discloses a method for recovering uranium from an acidic leach solution or leach pulp in salt water using an amino-phosphorus resin, wherein the liquid phase of the leach solution or leach pulp contains greater than 3 g/L chloride ion in solution. The resin may comprise a functional group comprising an amino phosphonic group, an amino-phosphinic group, an amino phosphoric functional group and/or a combination thereof. According to the invention the leach solution or leach pulp may be generated by in-situ leaching, vat leaching, heap leaching and/or agitated leaching at ambient, elevated temperature and/or elevated pressure conditions in saline or hyper-saline water. | 2014-02-13 |
20140044616 | METHOD FOR PRECIPITATING ONE OR MORE SOLUTES - The invention deals with a method for precipitating at least one solute in a reactor comprising: | 2014-02-13 |
20140044617 | METATHETIC COPPER CONCENTRATE ENRICHMENT - In one aspect, the invention provides processes for producing an enriched copper concentrate from a copper-and-nickel-containing ore. Processes of the invention may include an initial step of comminuting the ore, to provide a ground ore comprising copper minerals and nickel minerals. The ground ore may be subjected to a floatation process, to separate the ground ore into distinct fractions, such as first and second concentrates. A first concentrate may for example be made up of copper-enriched-and-nickel-containing solids, while a second concentrate is made up of nickel-enriched-and-copper-containing solids. The floatation process may for example fractionate the ore so that the concentration of copper minerals is higher in the first concentrate than in the ore, and the concentration of the nickel minerals is higher in the second concentrate than the ore. | 2014-02-13 |
20140044618 | Process of Gold and Copper Recovery From Mixed Oxide - Sulfide Copper Ores - The present invention relates to a process of gold and copper recovery from gold-containing copper ores obtained from mixed oxide-sulfide copper ore bodies by a series of flotation stages. More specifically, the present invention relates to a process of gold and copper recovery whereby gold-containing ores obtained from mixed oxide-sulfide copper ore bodies, and/or copper flotation by-products thereof, are subjected to at least one flotation step following a dewatering step. In particular, it recovers copper and gold from the oxidized zone of porphyry and other mixed ore deposits. Likewise, the present process allows recovery of copper and gold from the tailings and scavenger concentrates which, in conventional process are no longer viable for further treatment. | 2014-02-13 |
20140044619 | PROCESS FOR CONVERTING FGD GYPSUM TO AMMONIUM SULFATE AND CALCIUM CARBONATE - A continuous countercurrent flow process for converting FGD gypsum to ammonium sulfate and calcium carbonate including countercurrent flows with internal recycle of liquids to maximize the purity of reaction products while minimizing reaction times, and further include embodiments of the process that provide a yield of both ammonium sulfate and calcium carbonate to be 97 to 100%, and embodiments that provide for processes having a total time of reaction being 8 to 12 minutes, the invention further including processes for removing contaminants from the FGD gypsum employing an acid rinse process and/or a slurry tank reactor process. | 2014-02-13 |
20140044620 | METHOD FOR PRODUCING PRECIPITATED CALCIUM CARBONATE USING FOWL EGG SHELLS - The present invention relates to a method for producing precipitated calcium carbonate using fowl egg shells such as chicken egg shells. More particularly, the method comprises: a heat treatment step of heating fowl egg shells; a grinding step of grinding calcium oxide generated in the heat treatment step; a dry-quenching step of feeding the ground calcium oxide into a thermo-hygrostat to convert the ground calcium oxide into dry calcium hydroxide powder; a carbonizing step of mixing the dry calcium hydroxide powder prepared in the dry-quenching step with an organic solvent and feeding carbon dioxide generated in the heat treatment step into the mixture; and a filtering and drying step of filtering and drying the calcium carbonate obtained in the carbonizing step. | 2014-02-13 |
20140044621 | METHOD AND ARRANGEMENT FOR BURNING LIME MUD - The present invention relates to a method and an arrangement for burning lime mud into lime in a lime kiln The lime mud flows counter-currently to flue gases from a feed end to a firing end and the fuel used is flue gas that is produced by gasifying a fuel in the presence of combustion air in a gasifier. The combustion air for gasification is preheated with heat generated in lime mud combustion. The arrangement is provided with a conduit between the lime kiln and the gasifier for leading air from the lime kiln into the gasifier as combustion air. At least a portion of the combustion air for gasification is preheated with heat generated in the lime mud combustion so that air is led into cooling of lime obtained in the combustion and further into the kiln, from or through the firing end of which air is taken into the gasification. | 2014-02-13 |
20140044622 | PRODUCTION OF HIGH PURITY LITHIUM COMPOUNDS DIRECTLY FORM LITHIUM CONTAINING BRINES - A process for reducing the amount of magnesium in a lithium-containing brine by adding an aqueous solution of KCl to the brine to precipitate at least some of the magnesium as carnallite salt is disclosed. Lithium salts prepared using this magnesium removal process are also disclosed. | 2014-02-13 |
20140044623 | HIGH PERFORMANCE MERCURY CAPTURE - A method and system for high performance mercury capture from solid fuel combustion flue gas is provided. The method includes injecting pulverized activated carbon into a mercury capture system with at least a first and a second fabric filter, collecting the pulverized activated carbon captured in the second fabric filter, and injecting the collected pulverized activated carbon from the second fabric filter upstream of the first fabric filter for reuse to capture mercury from the process gas. | 2014-02-13 |
20140044624 | DETRITIATION DEVICE AND METHOD - The invention relates to a detritiation device comprising i) a furnace ( | 2014-02-13 |
20140044625 | HYDROCARBON TRAP HAVING IMPROVED ADSORPTION CAPACITY - A hydrocarbon trap is provided for reducing cold-start hydrocarbon emissions. The trap is formed by extruding from about 60 to 80% by weight zeolite and from about 20 to 40% by weight of a binder to form an extruded zeolite monolith. A three-way catalyst and an oxygen storage capacity material may also be included in the trap. The hydrocarbon trap contains from about 5.0 to 8.0 g/in. | 2014-02-13 |
20140044626 | FILTER SUBSTRATE COMPRISING THREE-WAY CATALYST - A catalysed filter for a positive ignition internal combustion engine comprises a porous filtering substrate having a total substrate length coated with a three-way catalyst washcoat composition comprising at least one precious metal selected from the group consisting of rhodium and one or both of platinum and palladium supported on a high surface area oxide, and an oxygen storage component, which composition being axially shared by a first zone comprising inlet surfaces of a first substrate lengthsecond zone; and a total precious metal loading in the first zone>second zone. | 2014-02-13 |
20140044627 | Preparation of Diesel Oxidation Catalyst Via Deposition of Colloidal Nanoparticles - The present invention relates to a process for preparing a catalyst, at least comprising the steps of adding a protecting agent to an aqueous solution of a metal precursor to give a mixture (M1), adding a reducing agent to mixture (M1) to give a mixture (M2), adding a support material to mixture (M2) to give a mixture (M3), adjusting the pH of mixture (M3), and separating the solid and liquid phase of mixture (M3). Furthermore, the present invention relates to the catalyst as such and its use as diesel oxidation catalyst. | 2014-02-13 |
20140044628 | COMPOSITION BASED ON OXIDES OF ZIRCONIUM, OF CERIUM, OF AT LEAST ONE RARE EARTH OTHER THAN CERIUM AND OF SILICON, PREPARATION PROCESSES AND USE IN CATALYSIS - The composition according to the invention is based on zirconium oxide, cerium oxide and at least one oxide of a rare earth other than cerium, in a proportion, by weight, of zirconium oxide of at least 5% and of cerium oxide of at most 90%, and it is characterized in that it additionally comprises silicon oxide in an amount, by weight, of between 0.1% and 2%. This composition may be used in catalysis, in particular in systems for treating the exhaust gases of internal combustion engines. | 2014-02-13 |
20140044629 | METHOD FOR TREATING A GAS CONTAINING NITROGEN OXIDES (NOx) USING A COMPOSITION COMPRISING ZIRCONIUM, CERIUM AND NIOBIUM AS A CATALYST - The invention relates to a method for treating a gas containing nitrogen oxides (NOx), in which an NOx-reduction reaction is carried out using a nitrogen-containing reducing agent, which invention is characterized in that the catalyst used for the reduction reaction is a catalytic system containing a composition comprising zirconium, niobium in the following percentages by weight, expressed in terms of the weight of oxide: 10-50% of cerium, 5-20% of niobium and the remainder consisting of zirconium. | 2014-02-13 |
20140044630 | CATALYZED SUBSTRATE AND EXHAUST SYSTEM FOR INTERNAL COMBUSTION ENGINE - An exhaust system for internal combustion engines, and a catalyzed substrate for use in an exhaust system, is disclosed. The exhaust system comprises a lean NO | 2014-02-13 |
20140044631 | COLD BED ADSORPTION SULFUR RECOVERY PROCESS - A process for removing sulfur from a gas stream is provided in which a plurality of reactor units, each comprising a condenser and reactor, are selectively operable under Claus reaction and cold bed adsorption conditions. The arrangement of reactor units within the plant is periodically changed following a front-middle-back sequencing scheme. This ensures that the final reactor unit in the series utilizes fully cooled catalyst which is most efficient for operation under cold bed adsorption conditions. In addition, the condenser of the final reactor unit in the series operates at or below the freezing point of sulfur thereby permitting even greater sulfur recovery. | 2014-02-13 |
20140044632 | METHOD AND APPARATUS FOR REMOVAL OF CARBON DIOXIDE FROM AUTOMOBILE, HOUSEHOLD AND INDUSTRIAL EXHAUST GASES - An exhaust processing assembly for an exhaust generating device, the exhaust processing assembly comprising one or more cartridges, each of the cartridges including a housing and a constituent housed in the housing and capable of at least partially removing carbon dioxide from the exhaust of the exhaust generating device, said constituent being one or more of a solid absorber and any other constituent, wherein the cartridges are one of: removable from the exhaust processing assembly and replaceable with other like cartridges, and refillable with new constituent. | 2014-02-13 |
20140044633 | CATALYTIC REDUCTION OF NOx WITH HIGH ACTIVITY CATALYSTS WITH PROPYLENE REDUCTANT - Methods and systems are provided for selective catalytic reduction of NOx with a low molecular low molecular weight hydrocarbon, e.g., propylene, as a reductant using a catalyst system including two catalysts. An exhaust stream containing an amount of NOx from a combustion operation is provided. A portion of the exhaust stream and a reductant stream including a low molecular weight hydrocarbon is introduced to a first catalytic reactor, which comprises a first catalyst including alumina loaded with silver. The NOx-reduced exhaust stream from the first catalyst is then directed to a second catalyst including zirconia loaded with at least one metal. | 2014-02-13 |
20140044634 | Ammonia Injection System For An HRSG - A heat recovery steam generator includes a casing for receiving exhaust gas from a turbine, a heat exchanger positioned within the casing for thermal communication with the exhaust gas, and an ammonia vapor distributor positioned within the casing. An ammonia vaporization unit is configured for conversion of aqueous ammonia to ammonia vapor and communication of the ammonia vapor to the distributor. A first extraction line operatively connects between the casing and the ammonia vaporization unit for communication of exhaust gas to the ammonia vaporization unit. A second extraction operatively connects between the casing and the ammonia vaporization unit for communication of exhaust gas to the ammonia vaporization unit. A catalytic reduction system is located within the casing and positioned downstream from the distributor for effecting a reaction between the ammonia vapor and NO | 2014-02-13 |
20140044635 | AMMONIA OXIDATION CATALYST, EXHAUST GAS PURIFICATION DEVICE USING SAME, AND EXHAUST GAS PURIFICATION METHOD - An ammonia oxidation catalyst being superior in heat resistance and capable of suppressing by-production of N | 2014-02-13 |
20140044636 | CATALYTIC REDUCTION OF NOx WITH HIGH ACTIVITY CATALYSTS - Methods and systems for selective catalytic reduction of NOx with an activated-carbon-supported metal catalyst at an operating temperature of between about between about 500° C. and about 750° C. An exhaust stream including NOx is introduced to a catalytic reactor having the activated-carbon-supported metal catalyst for NOx reduction of at least 90%. A second catalyst reactor can be provided downstream to remove or convert nitrous oxide as desired. | 2014-02-13 |
20140044637 | Method of pre treatment of lizardite - A method of pre treating lizardite for use in the mineral sequestration of carbon dioxide, the method including heating the lizardite at a temperature of less than 600° C. until the lizardite contains between about 10% to about 40% residual hydroxyls. | 2014-02-13 |
20140044638 | PROCESS FOR PRODUCING CARBONYL SULFIDE - An efficient process is provided in which sulfur is reacted with carbon monoxide in a liquid phase to produce carbonyl sulfide. In the presence of a base catalyst, carbon monoxide is continuously introduced into a reactor in which a liquid reaction mixture obtained by dissolving or suspending sulfur in an organic solvent is held, and the sulfur is reacted with the carbon monoxide at a pressure of 0.2-3.0 MPa and a temperature of 40-120° C. to yield carbonyl sulfide. The gaseous-phase part is withdrawn from the reactor, and the withdrawn gaseous-phase part is cooled with a cooler to condense the carbonyl sulfide contained in the gaseous-phase part. The condensed carbonyl sulfide is continuously withdrawn, and the gas that has not been condensed with the cooler is returned to the reactor. Thus, carbonyl sulfide is continuously produced. | 2014-02-13 |
20140044639 | Antibody Therapy - The present invention provides a composition comprising naked humanized, chimeric, and human anti-CEA antibodies and a therapeutic agent, which is useful for treatment of CEA expressing cancers and other diseases, and methods of use in treatment using this composition. | 2014-02-13 |
20140044640 | Combining Radioimmunotherapy and Antibody-Drug Conjugates for Improved Cancer Therapy - Described herein are compositions and methods of use of radionuclide-antibody conjugates (for RAIT) and drug-antibody conjugates (ADC). The combination of RAIT and ADC was more efficacious than either RAIT alone, ADC alone, or the sum of effects of RAIT and ADC. The unexpected synergy resulted in decreased tumor growth rate and increased survival, with a high incidence of tumor-free survival in Capan-1 human pancreatic cancer xenografts in nude mice. | 2014-02-13 |
20140044641 | POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF FOR TREATMENT OF IMMUNE RELATED DISORDERS AND CANCER - This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and drug development. This invention further relates to soluble LY6G6F, VSIG10, TMEM25 and LSR molecules, extracellular domains of LY6G6F, VSIG10, TMEM25 and LSR and conjugates, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. This invention further relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LY6G6F, VSIG10, TMEM25 or LSR molecules, which are suitable drugs for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders. | 2014-02-13 |
20140044642 | RADIOPHARMACEUTICAL IMAGING OF NEURODEGENERATIVE DISEASES - Methods for simultaneously detecting dementia or cognitive impairment, such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Lewy Body Dementia (LBD) and Vascular Dementia (VaD) in a patient using dual or multiple radiopharmaceutical probes are provided herein. | 2014-02-13 |
20140044643 | Magnetic Calcium Phosphate Nanoparticles, Applications And Methods Of Preparation Thereof - Magnetic calcium phosphate particles are provided including particles comprising iron oxide and calcium phosphate. A chitosan coating is present on the particles, wherein the particles are less than or equal to 1,000 nm, are magnetic and exhibit a positive charge in the range of 1 mVolts to 60 mVolts. The particles are provided by preparing a calcium hydroxide solution and filtering the calcium hydroxide solution in a membrane filter. An iron chloride solution is formed and combined with the filtered calcium hydroxide solution. In addition, the phosphoric acid solution is combined with the combined solutions of iron chloride and calcium hydroxide, forming a mixture including particles comprising iron oxide and calcium phosphate. | 2014-02-13 |
20140044644 | ANKYRIN G AND MODULATORS THEREOF FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS - The present invention generally relates to the technical field of medicine, in particular to the field of neurodegenerative, neurological and protein misfolding disorders such as amyloidosis. By establishing a role of ankG in APP processing the method of the present invention provides a new insight into the role of ankG in AD pathology and provides ankG as a target, drug, diagnostic agent and particularly as a vaccine in the treatment and diagnosis of the pathogenesis of Alzheimer's disease (AD). | 2014-02-13 |
20140044645 | DIAGNOSIS AND TREATMENTS RELATING TO TH2 INHIBITION - Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors. | 2014-02-13 |
20140044646 | Labeled, Non-Peptidic, Multivalent Integrin Antagonist Compounds; Methods for Synthesis and Uses Thereof - Disclosed are multivalent, integrin-receptor antagonists that are useful in a variety of therapeutic, prophylactic, and/or diagnostic imaging modalities. In illustrative embodiments, such compounds have been prepared and utilized in the imaging, detection, localization, and/or quantitation of one or more samples of biological interest. Similarly, these compounds, as well as formulations comprising them, find utility in the prevention, treatment, and/or amelioration of one or more symptoms of a disease, abnormal condition, dysfunction, etc., including, for example proliferative diseases such as cancer in affected animals. In certain embodiments, fluorescently- or radio-labeled-non-peptidic, multivalent integrin α | 2014-02-13 |
20140044647 | MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN CELLS AND USE THEREOF - The present invention relates to a microvesicle that is derived from nucleated mammalian cells, which are smaller than the nucleated cells. The microvesicles of the present invention can be used in the delivery of a therapeutic or diagnostic substance to specific tissues or cells, and more particularly, relates to microvesicles derived from monocytes, macrophages, dendritic cells, stem cells or the like, which can be used to deliver specific therapeutic or diagnostic substances for treating and/or diagnosing tissue associated with cancer, diseased blood vessels, inflammation, or the like. | 2014-02-13 |
20140044648 | ACTIVATABLE IMAGING CONTRAST AGENTS - An activatable probe and methods of using the same are provided. The activatable probe includes a superparamagnetic core and a polymeric matrix coating the metal oxide core. A paramagnetic agent encapsulated within the polymeric matrix. The polymeric matrix is configured to release the paramagnetic agent when subjected to a medium having a pH less than a normal physiological pH. | 2014-02-13 |
20140044649 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING - There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a β-sheet tape-like substructure. | 2014-02-13 |
20140044650 | HYDROGEL COMPOSITIONS DEMONSTRATING PHASE SEPARATION ON CONTACT WITH AQUEOUS MEDIA - A composition is provided, wherein the composition comprises a water-swellable, water-insoluble polymer or a water-soluble polymer, a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding to the hydrophilic polymer. The composition also includes a second water-swellable, water-insoluble polymer that provides for a phase separating film forming composition. Active ingredients, such as a whitening agent, may be included. The composition finds utility as an oral dressing, for example, a tooth whitening composition that is applied to the teeth in need of whitening, and removed when the degree of whitening has been achieved. In certain embodiments, the composition is translucent. Methods for preparing and using the compositions are also disclosed. | 2014-02-13 |
20140044651 | METHODS USEFUL IN STUDYING OR MODULATING SKIN OR HAIR PIGMENTATION, PLANT EXTRACTS FOR USE IN COMPOSITIONS AND COSMETIC CARE METHOD - The invention relates to methods useful in studying or modulating skin or hair pigmentation and to the use of plant extracts in compositions as well as to methods comprising the topical use of such compositions to reduce or to enhance skin or hair pigmentation. | 2014-02-13 |
20140044652 | Methods and Related Systems for Selecting or Customizing a Topical Treatment Regimen for a Mammalian Keratinized Surface - The invention described herein includes a method of selecting a treatment regimen for a surface of a mammalian keratinized tissue that includes illuminating the surface with a light source emitting long 5 wave UV light, thereby identifying at least one impaired region on the surface; categorizing the impaired region on the basis of its approximate UV perceptible color when exposed to the light source into at least one of a first category, a second category and a third category, wherein the approximate color substantially corresponds to a deficiency of the surface; and applying to the keratinized surface at least one treatment composition, wherein the 10 at least one treatment composition is formulated to treat, ameliorate or improve the deficiency in the surface. | 2014-02-13 |
20140044653 | TOPICAL COMPOSITION COMPRISING TRANSFORMED BACTERIA EXPRESSING A COMPOUND OF INTEREST - Compositions comprised of a population of transformed bacteria formulated for topical application to a subject are described. The population of transformed bacteria are created from a non-pathogenic bacteria and transformed to express a compound of interest for a therapeutic or a cosmetic purpose. In one embodiment, the composition is for protection of the skin from ultraviolet rays. | 2014-02-13 |
20140044654 | COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES - The present disclosure relates, according to some embodiments, to molecules, including conjugated fused polycyclic molecules, that may receive excited state energy from other molecules (e.g., light-absorbing molecules) or directly from the irradiation sources. According to some embodiments, the disclosure relates to molecules, including conjugated fused polycyclic molecules, that may resolve (e.g., quench, dissipate) excited state energy, normally by way of releasing it as heat. (e.g., as heat). Conjugated fused polycyclic molecules of various structures are disclosed including Formula III: | 2014-02-13 |
20140044655 | NOVEL ACTIVATOR PEPTIDES FOR SYNTHESIZING EXTRACELLULAR MATRIX PROTEINS, AND COSMETIC COMPOSITIONS INCLUDING SAME - This invention relates to new peptides activating extracellular matrix protein synthesis in the skin. | 2014-02-13 |
20140044656 | NOVEL USE - The present invention relates to the use of steviol as well as derivatives thereof as a skin tanning agent. Furthermore, the present invention relates to the cosmetic topical application of steviol and derivatives thereof formulated into a composition comprising a cosmetically acceptable carrier for skin tanning. Finally, the invention relates to the use of steviol for enhancement of melanin formation in human skin cells. | 2014-02-13 |
20140044657 | COSMETIC FORMULATION - The present invention relates generally to nail polish formulations for application to natural or artificial finger- or toenails, where the nail polish formulation comprises grapefruit seed extract that imparts antifungal and other antimicrobial properties. | 2014-02-13 |
20140044658 | Compositions and Methods for Treatment of Infections - This invention relates to the field of topical treatments for infections such as nail infections, particularly fungal infections of the nail commonly referred to as onychomycosis. Particularly, the invention relates to novel compositions containing peroxide for the treatment of such nail infections and other infections. | 2014-02-13 |
20140044659 | Compositions Having a Plurality of Discrete Emulsions - A cosmetic composition comprising a first emulsion and a second emulsion and optionally one or more additional emulsions, each of said two or more emulsions being discretely contained within the composition and comprising an inner phase and an outer phase, each of said two or more emulsions being independently a water-in-oil emulsion, an oil-in-water emulsion, an oil-in-oil emulsion, a polyol-in-oil emulsion, a water-in-silicone emulsion, a silicone-in-water emulsion, or a polyol-in-silicone emulsion in physical contact with at least one other emulsion, at least one of said two or more emulsions being visually distinct from the others, and each of said two or more emulsions as well as said composition being independently both physically and visually stable within the composition for at least six months at ambient temperature. | 2014-02-13 |
20140044660 | SOLID COSMETIC COMPOSITION IN COMPACT POWDER FORM - The present invention relates to a solid makeup and/or care cosmetic composition in the form of a compact powder, comprising, in a physiologically acceptable medium, at least: one pulverulent phase; one organopolysiloxane elastomer; one emulsifying system; one hydrophilic gelling agent; and one organic non-volatile oil present in a content of greater than or equal to 1% by weight relative to the total weight of the composition. The invention also relates to an intermediate composition for the preparation of such a cosmetic composition, to a process for manufacturing this cosmetic composition, and to a process for coating the skin with the said cosmetic composition. | 2014-02-13 |
20140044661 | CATIONIC POLYGLYCERYL COMPOSITIONS AND COMPOUND - Provided are polyglyceryl compositions comprising one or more polyglyceryl compounds having: (a) a node structure comprising at least three contiguous glyceryl remnant units; (b) one or more cationic groups each linked to the node structure by an independently selected linking group; and (c) one or more hydrophobic moieties each independently (i) linked to the node structure by a linking group, or (ii) constituting a portion of one of the one or more cationic groups, wherein the composition has an average degree of polymerization determined by hydroxyl value testing (DP | 2014-02-13 |
20140044662 | Producing Aqueous Solutions of Vinyllactam Polymers and Powders Thereof - Described is a process for producing aqueous solutions of vinyllactam polymers and solids obtainable therefrom by drying, especially polyvinylpyrrolidone, said process comprising using one or more sulfur components selected from the group consisting of sulfur dioxide, sulfurous acid and one or more salts of sulfurous acid, to reduce residual monomer. Also described are vinyllactam polymers obtainable by the process which have good stability in storage, the use of these vinyllactam polymers, and articles of manufacture and preparations comprising these vinyllactam polymers or obtained by use thereof. | 2014-02-13 |
20140044663 | Use of Glutamide Stabilizers - Fluids are provided which resist phase separation by inclusion of a stabilizing amount of a glutamic acid derivative in the presence of ethanol. The fluids comprise an aqueous discontinuous phase, a silicone oil containing continuous phase, a glutamic acid derivative such as dibutyl ethylhexanoyl glutamide, and ethanol. The fluids may be prepared without heating to solubilize the glutamic acid derivative | 2014-02-13 |
20140044664 | Compositions and Methods for Treating a Keratin Based Substrate - A composition containing sulfonated keratin with molecular weight distribution of about 96.8% 100 kDa to 100 Da and about 3.2% 250 kDa to 100 kDa, at least one cationic surfactant, and optionally an aqueous carrier. Generally the keratin is produced by a method involving treating wool with about 0.5 to about 1.0N NaOH in a bath volume:wool weight of about 5:1 to about 10:1 at about 40° C. to about 65° C. for about 4 to about 8 hours with dosing about every 1 to 3 hours with about 1% to about 10% by weight of bath of hydrogen peroxide. Also a method for treating a keratin based substrate involving contacting or applying the substrate (e.g., hair) with the composition. | 2014-02-13 |
20140044665 | COMPOSITION FOR KERATIN FIBERS - Present invention relates to a composition for keratin fibers especially for human hair comprising glycylglycine and/or its derivatives, an aromatic sulphonic acid and/or its salts and an anionic polymer for improving cosmetic properties of hair such as volume, body, elasticity and curl retention. | 2014-02-13 |
20140044666 | COMPOSITIONS CONTAINING CYCLODEXTRIN - A stable composition for removing unwanted molecules from a surface comprises functionally-available cyclodextrin, a cyclodextrin-compatible perfume material, and a cyclodextrin-incompatible perfume material. The compositions are suitable for capturing unwanted molecules from inanimate surfaces, including skin, hair, and the like. The compositions can further comprise other cyclodextrin-compatible and -incompatible materials and other optional ingredients. | 2014-02-13 |
20140044667 | HEALING COMPOSITION FOR TOPICAL APPLICATION - The present invention relates to a hygiene product or a pharmaceutical composition in the form of a gel or dressing, for topical application to the skin or mucosa including glycerol, at least one poly(meth)acrylate polymer, at least one polyethylene glycol having a molecular weight of less than 1000 g/mol, octanediol and water. | 2014-02-13 |
20140044668 | Methods for Predicting Cardiovascular Risks and Responsiveness to Statin Therapy Using SNPs - Methods and compositions for the effect of Cholesteryl ester transfer protein (CETP) polymorphisms on mRNA splicing, statin treatment outcome, response to CETP inhibitor drugs, and myocardial infarction risk are described. | 2014-02-13 |
20140044669 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY - The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein. | 2014-02-13 |
20140044670 | SKIN COMPOSITIONS AND METHODS OF USE THEREOF - Provided are therapeutic formulations and methods of use thereof. | 2014-02-13 |
20140044671 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS - Disclosed is a polymer or physiologically acceptable salt thereof. The polymer comprises a polymerized multifunctional amine monomer. The amine monomer comprises at least two amine groups and at least two acyclic nitrogen atoms that are connected through a —CH | 2014-02-13 |
20140044672 | CONJUGATES OF A GM-CSF MOIETY AND A POLYMER - Conjugates of a GM-CSF moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions comprising conjugates to a patient. | 2014-02-13 |
20140044673 | Classifying Skin Lesions Using Mass Spectrometry Proteomic Approach - The present invention provides for a mass spectrometry proteomic approach to distinguishing Spitz nevi from Spitzoid malignant melanoma. Histology directed mass spectral profiling allows for targeted analysis of sites of melanocytic lesion within formalin-fixed, paraffin embedded excisional biopsies. The classification system identified 5 peptide peaks, of which two have been identified as originating from vimentin and actin. A sensitivity and specificity for Spitz nevi of 97% and 90%, respectively, were achieved. | 2014-02-13 |
20140044674 | INTERLEUKIN-10 FUSION PROTEINS AND USES THEREOF - The present invention generally relates to fusion proteins of antibodies and interleukin-10 (IL-10). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease. | 2014-02-13 |
20140044675 | INTERLEUKIN-2 FUSION PROTEINS AND USES THEREOF - The present invention generally relates to fusion proteins of immunoglobulins and interleukin-2 (IL-2). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease. | 2014-02-13 |
20140044676 | USE OF TRUNCATED CYSTEINE IL28 AND IL29 MUTANTS TO TREAT CANCERS AND AUTOIMMUNE DISORDERS - Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or IL-29 polypeptide sequence and proteins fused to a polypeptide with IL-28 and IL-29 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer and/or autoimmune therapeutics. | 2014-02-13 |
20140044677 | TOPICAL COMPOSITION COMPRISING TRANSFORMED BACTERIA EXPRESSING A COMPOUND OF INTEREST - Compositions comprised of a population of transformed bacteria formulated for topical application to a subject are described. The population of transformed bacteria are created from a non-pathogenic bacteria and transformed to express a compound of interest for a therapeutic or a cosmetic purpose. In one embodiment, the composition is for protection of the skin from ultraviolet rays. | 2014-02-13 |
20140044678 | CHIMERIC NEWCASTLE DISEASE VIRUSES AND USES THEREOF - Described herein are chimeric Newcastle disease viruses engineered to express a heterologous interferon antagonist and compositions comprising such viruses. The chimeric Newcastle disease viruses and compositions are useful in the treatment of cancer. | 2014-02-13 |
20140044679 | Agent for Preventing Bacterial Wilt Disease, and Method for Preventing Bacterial Wilt Disease - Provided are: an agent for preventing bacterial wilt disease, which agent can prevent the development of bacterial wilt disease caused by various different bacterial wilt disease strains, that is, the development of bacterial wilt disease in various different plant varieties; and a method for preventing bacterial wilt disease utilizing the agent for preventing bacterial wilt disease. The agent for preventing bacterial wilt disease comprises as an active ingredient a wilt bacterium ( | 2014-02-13 |
20140044680 | Simian Subfamily B Adenoviruses SAdV-28, -27, -29, -32, -33, and -35 and Uses Thereof - A recombinant vector comprises simian adenovirus 28, simian adenovirus 27, simian adenovirus 32, simian adenovirus 33, and/or simian adenovirus 35 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses one or more simian adenovirus-28, -27, -32, -33, or -35 genes is also disclosed. Methods of using the vectors and cell lines are provided. | 2014-02-13 |
20140044681 | Cathepsin K As A Marker For Cartilage Production, Repair and Regeneration - Ctsk is used as a marker to identify, track, and manipulate Ctsk positive cartilaginous stem cells for cartilage repair and regeneration in vitro and in vivo. | 2014-02-13 |
20140044682 | GENERATION OF CARTILAGE EX VIVO FROM FIBROBLASTS - Embodiments of the invention encompass the ex vivo production of cartilage from chondrocytes differentiated from fibroblasts or stem cells. In particular embodiments, fibroblasts are subjected to conditions to produce chondrocytes in the form of cartilage tissue, for example cartilage having a desired shape. In at least some embodiments, a mold for the desired shape of the cartilage is produced from imaging of a body region of an individual in need thereof, and the fibroblasts are seeded in the mold with particular conditions. | 2014-02-13 |
20140044683 | CELL FUSION PROMOTER AND UTILIZATION OF THE SAME - The present invention provides a regeneration promoter for regenerating tissue with the use of somatic stem cells. The invention also provides a cell fusion promoter comprising ATP or its metabolite which is safely usable in vivo, a method of producing fused cells in the presence of ATP or its metabolite and a related pharmaceutical composition for regenerating or improving the function of a tissue or an organ in a subject suffering from dysfunction or hypofunction due to injury or denaturation. | 2014-02-13 |
20140044684 | Methods And Compositions For Regulating Gene Expression - In certain embodiments, the disclosure relates to compositions and methods relating to a translation-based gene regulation system that functions in mammalian cells. In certain specific embodiments, the disclosure relates to methods of regulating gene expression via modulating translation termination. | 2014-02-13 |
20140044685 | NUTRITIONAL COMPOSITIONS HAVING ALPHA-HICA AND CITRULLINE - Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include α-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, α-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided. | 2014-02-13 |
20140044686 | MOLECULAR MARKER FOR CANCER STEM CELL - A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker. | 2014-02-13 |
20140044687 | METHOD FOR USING REGULATORY T CELLS IN THERAPY - A method of regulatory cell therapy for a treating a patient in need thereof, wherein 10 | 2014-02-13 |
20140044688 | METHODS FOR SEPARATING CONSTITUENTS OF BIOLOGIC LIQUID MIXTURES - Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma while retaining the platelets and other facts. Highs speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants. | 2014-02-13 |
20140044689 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS - The disclosure generally describes methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject, such as diabetic retinopathy, cataracts, retinitis pigmentosa, glaucoma, macular degeneration, choroidal neovascularization, retinal degeneration, and oxygen-induced retinopathy. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof. | 2014-02-13 |
20140044690 | High-Energy Compounds for Use in Alzheimer's and Other Neurodegenerative Diseases - A method of treating or preventing a neurodegenerative disease includes administering an effective amount of a compound to a subject in need thereof. The compound includes a high-energy compound, such as adenosine triphosphate (ATP), guanosine triphosphate (GTP), phosphocreatine (PCr), acetyl coenzyme A (ACoA), phosphoenol pyruvate (PEP), or a combination thereof. | 2014-02-13 |
20140044691 | DIETARY SUPPLEMENT CONTAINING ALKALINE ELECTROLYTE BUFFERS - An improved dietary and/or therapeutic supplement composition comprising a quantity of a dietary and/or therapeutic supplement agent having a pH that upon ingestion with food or a beverage would limit the effectiveness of the agent and a sufficient amount of an alkaline electrolyte additive is provided in combination with the agent to raise the pH of the composition to a level of from about 8 to about 12.5 to increase the effectiveness and functional utilization of the agent while the composition is in the person's stomach. | 2014-02-13 |
20140044692 | IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY - Some aspects of the invention provide for a method of treating Impaired Energy Processing Disorders and Mitochondrial Deficiencies using polyunsaturated fatty acids which are modified in certain positions to attenuate oxidative damage by Reactive Oxygen Species (ROS) and/or suppress the rate of formation of reactive products and toxic compounds. | 2014-02-13 |
20140044693 | OXIDATIVE RETINAL DISEASES - Some aspects of the invention provide for a method of treating Wet and/or Dry Age-related Macular Degeneration, Retinitis Pigmentosa, Diabetic Retinopathy, cataracts, and/or Stargardt Disease using polyunsaturated fatty acids which are modified in certain positions to attenuate oxidative damage by Reactive Oxygen Species (ROS) and/or suppress the rate of formation of reactive products and toxic compounds. | 2014-02-13 |
20140044694 | PHARMACEUTICAL COMPOSITION FOR TREATING LYSOSOMAL STORAGE DISEASE - The purpose of the present invention is to provide, in a simple and also inexpensive manner, a pharmaceutical composition which comprises a plurality of lysosomal enzymes and is effective in treating lysosomal storage disease caused by a deficiency in a plurality of lysosomal enzymes. Provided is a pharmaceutical composition for treating lysosomal storage disease, the composition comprising as an active ingredient a lysosomal enzyme group obtained from cells derived from a subject who does not suffer from lysosomal storage disease. | 2014-02-13 |
20140044695 | BOTULINUM TOXIN COMPOSITIONS - A high potency botulinum toxin pharmaceutical composition comprising two excipients (such as albumin and sodium chloride) in a weight to weight ratio of between about 1 and about 100. | 2014-02-13 |