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06th week of 2022 patent applcation highlights part 8
Patent application numberTitlePublished
20220040010ABSORBENT ARTICLE2022-02-10
20220040011SELF-ADHESIVE ABSORBENT HYGIENIC PATCH WORN ON THE BODY - A self-adhesive absorbent patch includes an absorbent layer that is an outermost layer when the self-adhesive absorbent patch is applied to a user's body and/or garment and absorbs liquids, droplets, and/or moisture expelled by the user, a resistant or impermeable layer that is bonded to the first layer and prevents or limits the liquids, droplets, and/or moisture absorbed from the absorbent layer from being deposited onto the user's body and/or garment, an adhesive layer comprised of a double-sided adhesive, wherein a first side of the double-sided adhesive adheres to the resistant or impermeable layer and a second side of the double-sided adhesive adheres to the user's body and/or garment when the user applies the self-adhesive absorbent patch to the user's body and/or garment, and a release liner that is removably attached to the adhesive layer before the user applies the self-adhesive absorbent patch to the user's body and/or garment.2022-02-10
20220040012A PACKAGE OF ABSORBENT UNITS AND A METHOD FOR MANUFACTURING SUCH A PACKAGE - The present disclosure relates to a package (2022-02-10
20220040013Bariatric Lift Assist Device - A patient lifting apparatus designed to facilitate the lifting patients off the ground having a backboard having a perimeter, a patient receiving surface and an opposingly located lower surface having opposingly located bases thereon, each of the bases having opposingly located curved sections and a flat middle section located in between the curved sections.2022-02-10
20220040014WHEELCHAIR FRAME AND WHEELCHAIR COMPRISING THE SAME - There is described a wheelchair frame including first and second side frame members each having a first, rearward section designed to be coupled to a seat portion of a wheelchair and a second, forward section designed to be coupled to a foot portion of the wheelchair wherein the rearward and forward sections are connected to one another to form a substantially L-shaped profile. Each of the first and second side frame members exhibits, at least in part, a varying cross-section and further has an intermediate section shaped to act as a hand grip, which intermediate section is interposed between the rearward and forward sections and exhibits a cross-section that differs from a cross-section of the rearward section and/or forward section. The rearward section, the intermediate section and the forward section are successive sections of a same integral piece that is shaped to exhibit the varying cross-section. The rearward section exhibits a substantially circular cross-section and the forward section exhibits a substantially polygonal cross-section, the intermediate section being a substantially rectilinear section and exhibiting a varying cross-section that transitions gradually from the substantially circular cross-section of the rearward section to the substantially polygonal cross-section of the forward section.2022-02-10
20220040015THE WHEELCHAIR DRIVE UNIT AND THE METHOD OF MOUNTING THE DRIVE UNIT TO A WHEELCHAIR - After manually setting the length of the variable length connecting element (2022-02-10
20220040016REMOVABLE ELECTRIC PROPULSION SYSTEM FOR A ROLLING OBJECT - SIMULTANEOUS AND COMBINED GRIPPING AND LIFTING OF THE WHEELS IN THE LONGITUDINAL DIRECTION - The present invention relates to a removable electric propulsion system (2022-02-10
20220040017DEVICE FOR SUPPORTING A BODY PART - A method of supporting a body part (2022-02-10
20220040018Smart Bed or Mattress for Reducing Pressure Ulcers Which Uses Adjustable Orthogonal Straps to Create Low-Pressure Areas - This invention is a smart bed or mattress for reducing pressure ulcers with an orthogonal array of movable straps or layers which creates a low-pressure area. The location of the low-pressure area is selected to be under a portion of a person's body which is at risk for getting a pressure ulcer. A low-pressure area can be created: where straps which have been slackened overlap; where elastic segments of movable straps overlap; or where the movement of straps creates an opening.2022-02-10
20220040019System And Methods For Supporting And Positioning A Person - A system for supporting and positioning a person. A flexible cover layer defines a support surface for the person, and a formable layer is coupled to the flexible cover layer. The formable layer includes a sealed bladder adapted to be in fluid communication with a vacuum source, and particles disposed within the sealed bladder. The system is operable in a first configuration in the absence of the vacuum, and a second configuration in the presence of the vacuum. In the first configuration, the particles are substantially movable relative to one another such that a contour may be provided to the support surface. In the second configuration, substantially immovable relative to provide rigidity to the formable layer to maintain the contour. A controller coupled to sensors may control the vacuum source to move said system between the first and second configurations. Methods of supporting and positioning the person are also disclosed.2022-02-10
20220040020High-Access Patient Transport Shield - A patient transport shield provides for a flexible support sheet supporting a patient with upstanding ribs holding a transparent cover over the patient to provide a patient volume that may hold negative pressure when the transparent cover is attached to the support sheet by a resealable pressure-sensitive attachment strip allowing rapid assembly and ready access to the patient.2022-02-10
20220040021SPINAL DEFORMITY CORRECTION AND FUSION SURGERY SUPPORTING DEVICE - A spinal deformity correction and fusion surgery supporting device is capable of simplifying the operative procedures of a spinal deformity correction and fusion surgery by an operator to reduce the operative time and lessen the burden on the patient and achieving a more effective correction rate by the spinal deformity correction and fusion surgery. In this supporting device, the waist and the vicinity thereof are pressed from both sides in the left-right direction by a pair of waist pressing bodies, and the chest and the vicinity thereof are pressed from both sides in the left-right direction by a pair of chest pressing body to establish a trunk balance. In this state, the pair of chest pressing bodies and the pair of waist pressing bodies are moved away from each other to apply a tensile load to spinal deformity and a state in which the spinal deformity is corrected so as to approach a correction rate by the spinal deformity correction and fusion surgery can be maintained. As a result, a more effective correction rate is achieved by spinal deformity correction and fusion surgery while simplifying the operative procedures of spinal deformity correction and fusion surgery, shortening the operative time, and lessening the burden on the patient.2022-02-10
20220040022TABLE COLUMN FOR AN OPERATING TABLE HAVING A REINFORCING MECHANISM FOR A CYLINDRICAL GUIDE - A table column (2022-02-10
20220040023FUNERARY VIEWING SYSTEM AND METHOD - A funerary method includes disposing a deceased adult human body in supine position on an insert constructed of paper material having side walls and end walls. The method further includes providing the insert on a tray having two end panels and a plurality of side panels affixed to a bottom panel, and inserting a first edge of a first fabric segment between a side panel of the tray and a side wall of the insert. The first fabric segment is used to cover at least a portion of a top edge of at least the first side wall of the insert and at least a portion of the deceased human body, such that the deceased human body is sufficiently visible for identification. Thereafter, the insert and the deceased human body are removed from the tray.2022-02-10
20220040024SEATING-TYPE GAIT REHABILITATION ROBOT IMPROVED IN ENTRY CHARACTERISTICS - Proposed is a seating-type gait rehabilitation robot improved in entry characteristics, and more particularly to a seating-type gait rehabilitation robot improved in entry characteristics, of which a structure is concise and simple, and in which a footrest on which a trainee can put his/her foot has the minimum height to allow the trainee to easily enter and readily use the robot without any separate entry means for entry of the trainee and is placed at an entry side for the trainee to raise a gait training effect and reduce a collision risk.2022-02-10
20220040025ASSIST DEVICE - An assist device includes a first body-worn unit, second body-worn units, an actuator, a detection part, a controller configured to obtain an assist parameter for causing the actuator to generate a desired assist force, and perform control for causing the actuator to operate at an output corresponding to the assist parameter. When the user performs a forward leaning action, the controller obtains the assist parameter for providing the user with the assist force in a direction of bringing the user to an upright standing posture based on the tilt angle and a time-based change in the tilt angle. The controller is configured to further perform an assistance moderation process to reduce the assist force when the time-based change in the tilt angle increases.2022-02-10
20220040026WIRE-DRIVEN WRIST THREE-DEGREE-FREEDOM TRAINING MECHANISM FOR REHABILITATION OF UPPER LIMBS - The invention discloses a wire-driven wrist three-degree-freedom training mechanism for rehabilitation of upper limbs, and relates to the field of upper limb rehabilitating mechanical structures. The wire-driven wrist three-degree-freedom training mechanism comprises a wrist executing mechanism, a wrist linking mechanism, a forearm mechanism and an elbow linking mechanism. The wire-driven wrist three-degree-freedom training mechanism disclosed by the invention adopts a wire-driven design, through comprehensive utilization of two rotation pairs in the training mechanism, wrist three-degree-freedom passive training is realized through two driving motors; through the implementation of the wire-driven wrist three-degree-freedom training mechanism, a patient can adopt a passive training manner to perform rehabilitating training of the upper limbs; the wire-driven wrist three-degree-freedom training mechanism is provided with a position compensation mechanism, and can be adapted to individual differences of different patients, so that the training effect and user experience of the patient are improved; the mechanism is simple, the radiation and noise of the motors are low, and mental pressure of the patient can be reduced.2022-02-10
20220040027CONTROL AND SENSOR SYSTEM FOR DEVICES ASSISTING IN JOINT FLEXION - Embodiments of the present disclosure are directed to devices for assisting joint flexion. Devices for assisting joint flexion can include a wearable component configured to fit over a user's finger, an actuator interface positioned at a joint of the user's finger, and a force sensor on a palmar side of a user's finger joint on an exterior surface of the wearable component. A force sensor measures an overall force applied to an object by a contact surface of the wearable component. Such devices can also include a motor coupled with the wearable component that provides the mechanical driving force to the actuator interface to assist with flexion of the user's finger joint.2022-02-10
20220040028EXOSKELETON FINGER REHABILITATION TRAINING APPARATUS - An exoskeleton finger rehabilitation training apparatus includes a housing. A first motor and a second motor are disposed inside the housing. A direction of an output shaft of the first motor is opposite to a direction of an output shaft of the second motor. The output shaft of the first motor is provided with a first motor gear. A right side of the first motor gear is engaged with a first transmission gear. An edge of the first transmission gear is sequentially connected to an index finger sleeve and a middle finger sleeve that are axially arranged. The output shaft of the second motor is provided with a second motor gear. A right side of the second motor gear is engaged with a second transmission gear. An edge of the second transmission gear is sequentially connected to a pinky sleeve and a ring finger sleeve that are axially arranged.2022-02-10
20220040029ANTI-TIPPING APPARATUS FOR WALKERS - Systems and methods are disclosed for preventing tipping of a walking aid including a sensor configured to detect an angle of tilt in a forward direction of a walking aid, an actuator configured to determine whether the angle of tilt crosses a pre-set threshold, and a retractable support that prevents tipping of the walking aid, wherein the actuator causes the retractable support to extend from the walking aid in the forward direction to limit the tilt of the walking aid when the actuator determines that the angle of tilt crosses the pre-set threshold.2022-02-10
20220040030Massage Head for Massage Gun and Massage Gun Containing the Same - A massage head for a massage gun and a massage gun containing the same, relates to the technical field of massage devices, and solves the technical problem of the single function of the massage gun. The massage head comprises a massage head cover, a massage member, a cooling and heating component and a conductive quick-connecting component; wherein the massage head cover and the massage member are provided oppositely, the massage head cover and the massage member encircle an accommodating cavity for accommodating the cooling and heating component, and the conductive quick-connecting component is provided at the end of the massage head cover away from the massage member and electrically connected to the cooling and heating component; the massage head is detachably electrically connected to the massage gun body through the conductive quick-connecting component; the massage gun comprises a massage gun body, a grip handle, a reciprocating driving mechanism, a main circuit board, and a massage head.2022-02-10
20220040031MUSCLE MASSAGING BELT ASSEMBLY - A muscle massaging belt assembly is designed to be worn around a person's torso or limbs. A buckle member and latch member of the belt assembly is designed to be coupled or uncoupled. A variable length strap portion of the belt assembly is slidably looped back from the buckle or latch member and is designed to be shortened or lengthened to increase or decrease the circumference of the fastened buckle and latch members. A detachable, laterally extendable or expandable, planar platform is disposed in a substantially middle portion of the belt assembly, a rechargeable battery disposed within. One or more mounting assemblies are disposed on an inner face of the platform. A plurality of detachable knob assemblies is coupled to the mounting assemblies, a battery assembly disposed within, a top of each knob designed to abut the torso or a limb of a user. An electric vibration motor is within each knob assembly.2022-02-10
20220040032HAND-HELD MASSAGE GUN AND CONVERSION MECHANISM THEREOF - A hand-held massage gun and conversion mechanism thereof are disclosed. The hand-held massage gun includes a massage gun body and a conversion mechanism. The massage gun body includes an output rod. The conversion mechanism includes a hollow shell, a movable block and return springs. The hollow shell is detachably connected to the massage gun body, and two ends of the hollow shell are provided with an opening and a long hole. The movable block is accommodated in the hollow shell. The movable block has an inclined surface, an abutting portion and a linkage rod inserted in the long hole. The output rod is inserted in the opening and abutted against the inclined surface. The return springs are elastically supported between the hollow shell and the abutting portion.2022-02-10
20220040033DEVICE FOR MITIGATING MOTION SICKNESS AND OTHER RESPONSES TO INCONSISTENT SENSORY INFORMATION - Embodiments disclosed herein mitigate motion sickness by disrupting, controlling, or influencing anatomy of the vestibular system. An embodiment may induce vibrations in the vestibular system, including otoliths and/or semicircular canals of the inner ear, causing noisy or unreliable sensory information to be sent to the brain from the vestibular system. Due to the noisy or unreliable quality, the brain, as part of a normal physiological response, may rely less on sensory information from the vestibular system and rely more on other sources, thereby mitigating the motion sickness response, vertigo, vestibular migraines, and other physiological responses to inconsistent sensory information. Vibrations in the vestibular system may be induced by an agitator placed on an individual's head near the vestibular system, or by a transducer placed near the eardrum or directly on an individual's head. Some embodiments may optionally include implantable components in addition to extracorporeal components.2022-02-10
20220040034Massage System of Vehicle and Method of Controlling the Same - A massage system for a seat of a vehicle includes a drive motor, a sliding member having a hollow pillar shape, a first end of the sliding member being blocked by a plate member and a second end of the sliding member being opened, a housing member having a hollow pillar shape, a first end of the housing member being blocked by a partition and a second end of the housing member being opened, and a drive gear module operably connected to the drive motor, wherein at least one roller member is extended toward the housing member at an edge of the plate member, and at least one cam protruding toward the sliding member is formed at a circumference of the partition, wherein a cam profile is formed at a surface of the cam.2022-02-10
20220040035TRACKING OF CARDIAC RESUSCITATION PROCEDURE AND TRANSITIONS OF CARE - Systems, methods, and computer program products for tracking of cardiac resuscitation procedures and transitions of care are disclosed. The method includes displaying on a first device one or more timers and a plurality of inputs, the plurality of inputs comprising patient health data, patient interventions, and medical events. The one or more timers, a feed of the medical events, and the patient interventions are displayed on a second device. One or more selections of the plurality of inputs are received from a user. A recommended cardiac resuscitation step is determined based on the user selections. The displaying on the second device is updated based on the one or more user selections and the recommendation. In various embodiments, a hand-off procedure may be implemented to transfer patient data, timers, event data, and/or user privileges from one healthcare professional to another.2022-02-10
20220040036CPR CHEST COMPRESSION DEVICE WITH RELEASABLE BASE MEMBER - A CPR device having a base member configured to be placed underneath a patient, a chest compression mechanism configured to deliver CPR chest compressions to the patient, a support leg configured to support the chest compression mechanism at a distance from the base member, a clamp mechanism coupled to the support leg, and a release mechanism coupled to the support leg and the clamp mechanism. The clamp mechanism is configured to attach the support leg to a lock component of the base member in a latch-closed configuration and to release the support leg from the lock component in a latch-open configuration. The clamp mechanism is further configured to transition from the latch-closed configuration to the latch-open configuration when the lock component of the base member impacts an external portion of the clamp mechanism without the release mechanism being pulled away from the base member.2022-02-10
20220040037PRESERVATIVE REMOVAL FROM EYE DROPS - A particulate plug for removing a preservative from a solution, suspension, or emulsion comprising a drug is presented. The plug comprises microparticles of a hydrophobic polymer/fatty acid blend. The microparticles of hydrophobic polymer/fatty acid blend selectively absorb preservative allowing the drug to remain in solution for delivery.2022-02-10
20220040038GLASS PACKAGING ENSURING CONTAINER INTEGRITY - A strengthened glass container or vessel such as, but not limited to, vials for holding pharmaceutical products or vaccines in a hermetic and/or sterile state. The strengthened glass container undergoes a strengthening process that produces compression at the surface and tension within the container wall. The strengthening process is designed such that the tension within the wall is great enough to ensure catastrophic failure of the container, thus rendering the product unusable, should sterility be compromised by a through-wall crack. The tension is greater than a threshold central tension, above which catastrophic failure of the container is guaranteed, thus eliminating any potential for violation of pharmaceutical integrity.2022-02-10
20220040039INTRAVENOUS FLUID BAG WARMER - A warming sleeve for an intravenous fluid bag includes a heating element. The warming sleeve can include an elastic materially at least partially surrounding the heating element. The warming sleeve can include a layer of a material disposed between the heating element and an intravenous fluid bag. The layer of material can exchange heat between the heating element and a fluid within the intravenous fluid bag.2022-02-10
20220040040VALVE WITH ON-OFF MECHANISM FOR BAG USED FOR CONDITIONING, RECONSTITUTING AND/OR DILUTING OF INJECTABLE PRODUCTS - This CIP, Continuation-in-part, presents constructive details of the material contained in the original document BR 10 2016 016091-0 and not specified until then, and the valve (2022-02-10
20220040041VIAL ADAPTER - An exemplary vial adapter may include a moveable member, an elongated member with a first passage, a second passage coupled to an expandable first reservoir, and a third passage coupled to an expandable second reservoir. In a first orientation of an exemplary vial adapter, a fluid may be directed through the first passage into the first reservoir or the second reservoir. In a second orientation of an exemplary vial adapter, a fluid may be drawn through the first passage and a fluid drawn through an air passage into the second passage. In a second orientation of an exemplary vial adapter, a fluid may be directed through the first passage and through the third passage into the second reservoir. In a first orientation of an exemplary vial adapter, a moveable member may be activated to direct a fluid from the second reservoir through the third passage.2022-02-10
20220040042LIQUID TRANSFER DEVICES FOR USE WITH INTRAVENOUS (IV) BOTTLES - A liquid transfer device is provided having a trifurcated body that includes a vial adapter at a first end configured to telescopically mount on the crown of an IV bottle to puncture a stopper in the crown with a cannula, an IV port extending from an opposing second end of the trifurcated body, and a needleless self-sealing port extending from a third end of the trifurcated body and configured to couple with the male connector of an additive transfer device. Methods of using the liquid transfer device with an IV bottle, additive transfer device, and an infusion set to prepare an infusion liquid for administration to a patient are also provided.2022-02-10
20220040043NEEDLELESS CARTRIDGE FOR AUTOMATIC DRUG COMPOUNDER - Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needleless fluid port and a needleless vent port for fluid coupling to a vial via a vial puck. The vial puck includes corresponding needleless fluid and vent ports and a cannula. The cannula is extendible, by insertion of a protrusion on the cartridge into a shaft of the vial puck, into the vial to couple the vial to the needleless fluid and vent ports.2022-02-10
20220040044ROTARY VALVE PUMP FOR AUTOMATIC DRUG COMPOUNDER - Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes controllable fluid pathways. One or more rotary piston pump/valves may be used to move fluid and/or gasses through the various fluid pathways of the cartridge. For example, the cartridge may include a dedicated rotary piston pump/valve for each process that moves fluid and/or gas through the cartridge. When turning, the rotary piston pump/valve acts as a pump to move the fluid or gas, and when the rotary piston pump/valve stops turning, it effectively acts as a shutoff valve, preventing any fluid flow. Magnetic couplers for the cartridge may be provided on a pump head of the compounder system.2022-02-10
20220040045BABY FEEDING BOTTLE - A baby bottle device (2022-02-10
20220040046Securement Assembly for Enteral and Vesical Access Devices and Related Methods - The present disclosure provides a securement assembly for an enteral access device or vesical access device (“access device”). The securement assembly includes a base and a lid. The base is generally configured to support an external port of the access device and the lid is pivotably coupled to the base. The base comprises a border rim and a central portion, wherein the border rim is configured to engage a skin surface of a patient around a stoma and the central portion is configured to engage the external port of the access device. The central portion may comprise opposing side arms defining an aperture through which a tube of the access device extends.2022-02-10
20220040047PACIFIER - Suggested is a pacifier, comprising a mouthpiece and a shield further including a vibration-generating device.2022-02-10
20220040048DENTAL GLASS POWDER AND DENTAL COMPOSITION - A dental glass powder includes 15 to 40% by mass of zinc oxide (ZnO), 20 to 55% by mass of silicon oxide (SiO2022-02-10
20220040049Depilatory Wax Additive and Process - A depilatory wax additive and process. The depilatory wax additive may modify a depilatory hard wax composition to include visual, olfactory, or skin treatment components. A depilatory wax additive may include molded hard wax component and glitter, a color modifier, a scent modifier, or a skin treatment. A preexisting hard wax composition of solid particles may be heated to a liquid. The depilatory wax additive may be added to the liquefied preexisting hard wax composition, mixed, and heated to disperse the glitter, a color modifier, a scent modifier, or a skin treatment in the wax mixture.2022-02-10
20220040050NONWOVEN FABRIC FOR SKIN CARE PRODUCTS, FACE MASK, AND CLEANSING SHEET - Provided is a nonwoven fabric for skin care products. The nonwoven fabric includes: a thermoplastic resin fiber having a single fiber diameter of 50 nm or more and 800 nm or less; and a cellulose fiber. A tensile strength of the cellulose fiber measured in accordance with JIS L 1015:2010 8.7.2 is 1.9 cN/dtex or less, a total content of the thermoplastic resin fiber and the cellulose fiber is 85% by mass or more relative to a total mass of the nonwoven fabric for skin care products, a content ratio by mass of the thermoplastic resin fiber and the cellulose fiber (thermoplastic resin fiber/cellulose fiber) is 0.23 to 1.50, and a density of the nonwoven fabric for skin care products is 0.08 g/cm2022-02-10
20220040051COMPOSITION - A solid cosmetic composition includes: (i) a surfactant; (ii) a wax; and (iii) aquafaba.2022-02-10
20220040052Compositions and Methods for Preparation of Solidified Oil for Treating Hair and Scalp - The present disclosure discloses a composition for solidified oil embodied in a dispenser for treating hair and scalp by moisturization. The composition comprising a blend of natural oils; essential oils; vitamins to provide antioxidants to the scalp; at least one thickening agent is mixed to increase the viscosity of the mixture formed; a tubular dispenser for holding the solidified oil composition formed from the mixture; a turning screw present on the bottom of the tubular dispenser for allowing the solidified oil composition to protrude out of the tubular dispenser when the turning screw is moved to an anti-clockwise direction, wherein the solidified oil composition is moved downwards when the turning screw is moved to a clockwise direction; and a cap for enclosing the tubular dispenser housed with the solidified oil composition.2022-02-10
20220040053MICROPARTICLES OF CELLULOSE NANOCRYSTALS WITH PIGMENT NANOPARTICLES BOUND THERETO AND METHOD OF PRODUCTION THEREOF - Microparticles comprising carboxylated, sulfated, or phosphated cellulose nanocrystals (CNCs) and pigment nanoparticles are provided. In these particles, the cellulose nanocrystals and the pigment nanoparticles are agglomerated together thereby forming said microparticle, and wherein the pigment nanoparticles are bound to the surface of the cellulose nanocrystals. Cosmetic preparations comprising these microparticles are also provided. Finally, a method for producing the microparticles is provided. The method comprises the steps of a) producing an aqueous suspension of carboxylated, sulfated, or phosphated CNCs with pigment nanoparticles bound thereto; and b) drying said aqueous suspension to produce the microparticles.2022-02-10
20220040054LONG WEAR LIP COSMETIC SYTEM AND TOPCOAT - A cosmetic system including a lip basecoat composition that includes at least one first silicone film-forming agent, colorant, and a volatile hydrocarbon oil, and a topcoat composition including at least one second silicone film-forming agent in a non-volatile oil carrier. Methods and topcoats are also provided.2022-02-10
20220040055AQUEOUS GELS FOR DYEING OR MAKING UP THE EYEBROWS - The present invention relates to a cosmetic process for dyeing or making up keratin fibres, in particular the eyelashes and/or the eyebrows and preferably the eyebrows, comprising the application, to said keratin fibres, of at least: a) A dyeing cosmetic composition A comprising, in a physiologically acceptable medium, one or more natural dye(s) chosen from the group consisting of neoflavonoids, gallic tannins and catechin tannins, and/or proanthocyanidins and derivatives thereof and mixtures thereof, or one or more plant extracts containing same, and advantageously an antioxidant, b) A revealing cosmetic composition B comprising, in a physiologically acceptable medium, at least one iron salt and/or one aluminium salt, in particular an iron gluconate or an iron sulfate, wherein the composition A is applied before or after the composition B, preferably before the composition B.2022-02-10
20220040056HAIR COMPOSITIONS AND METHODS OF USE THEREOF - Hair spray compositions comprising a liquid carrier, hollow, fluid-filled microspheres, a polymer fixative, and propellant are provided.2022-02-10
20220040057Silicone Free Emulsion-Based Personal Care Compositions and Methods for the Same - A personal care composition and methods for determining a stability of the personal care composition are disclosed. The personal care composition may include an emulsion of a hydrophobic phase and a hydrophilic phase. The hydrophobic phase may include an emulsifying system including one or more amino acid surfactants, such as a glutamate surfactant.2022-02-10
20220040058COSMETIC HAIR COMPOSITION IN THE FORM OF A NANOEMULSION COMPRISING A PARTICULAR NON-IONIC SURFACTANT AND A PROPELLANT - The present invention relates to a cosmetic composition in the form of a nanoemulsion comprising at least one particular non-ionic surfactant, at least one fatty substance, water and at least one propellant. The invention also relates to an aerosol device and also to a process for styling keratin fibres using such a composition.2022-02-10
20220040059OIL-IN-WATER COSMETIC AND METHOD FOR PRODUCING THE SAME - An oil-in-water cosmetic composed of an aqueous phase and an oil phase and comprising hydrophobized inorganic powder, a fatty acid soap, a nonionic surfactant and a hydrophilic polymer, including an oil that contains a non-silicone oil and including hydrophobized iron oxide powder and hydrophobized pigment-grade titanium oxide powder in the oil phase and the aqueous phase, wherein the contents of the hydrophobized pigment-grade titanium oxide powder in the oil phase and in the aqueous phase are, respectively, greater than 0.5 mass % and less than 5 mass %, and greater than 2.5 mass % and less than 20 mass %, the nonionic surfactant has an overall HLB value of 6 to 15, an aminoalkylsulfonic acid polymer is contained as a hydrophilic polymer, and the total non-silicone oil content is greater than 5 mass % and less than 30 mass %.2022-02-10
20220040060WATER-IN-OIL COMPOSITION FOR EXTERNAL APPLICATION TO SKIN - A water-in-oil composition for external application to the skin includes an oily component containing an oil-soluble external skin component and an oily solvent, and an aqueous component containing a water-soluble polymer. The water-soluble polymer includes at least one selected from the group consisting of carboxyvinyl polymers, polyacrylic acid, poly(2-acrylamido-2-methylpropanesulfonic acid), and salts thereof. A content by percentage of the oily solvent in the oily component is 50% by mass or greater with respect to the mass of the oily component. Solubility of the oil-soluble external skin component to the oily solvent is lower than the solubility thereof to diisopropyl sebacate.2022-02-10
20220040061MULTI-PHASE ORAL COMPOSITION FOR DELIVERING ORAL CARE ACTIVE AGENTS - A multi-phase oral composition for delivering active agents.2022-02-10
20220040062DEPOSITION SYSTEM FOR HAIR - A hair treatment composition comprising: a) a conditioning base comprising: i) a cationic conditioning surfactant having from 16 to 32 carbon atoms; ii) a fatty alcohol having from 8 to 22 carbon atoms; and b) from 0.1 to 10 wt % of a microcapsule in which a core comprising benefit agent is encapsulated in a polymeric shell; and (c) from 0.1 to 5 wt % of a diesterquat, provides improved deposition of microcapsules and delivery of benefit agent to hair surfaces.2022-02-10
20220040063Liquid Cosmetic - The invention provides a liquid cosmetic that contains at least a capsule in an aqueous phase, wherein the capsule comprises agar shell encapsulating an oil component, and the aqueous phase comprises one thickener selected from the group consisting of a (meth)acrylic polymer and a polysaccharide, and an amphiphilic substance having an HLB value of no greater than 13.2022-02-10
20220040064Oral Care Compositions and Methods of Use - Disclosed herein are improved oral care formulations comprising precipitated calcium carbonate (PCC) and synergistic preservative combinations selected. Methods of making and using the compositions are also provided.2022-02-10
20220040065COMPOSITIONS AND METHODS FOR PREVENTION OF VIRAL INFECTIONS AND ASSOCIATED DISEASES - Described herein are single-phase multi-component compositions and methods for their use reducing the viral load of infectious viruses on host organisms, including but not limited to Influenza A, Rhinovirus Type 14, Adenovirus Type 5, Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2; COVID-19 virus), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), and Human coronavirus 229E. The compositions described herein comprise a combination of an oxidative compound and a buffering system. The methods of use of these compositions as antiviral agents when applied to the oral, nasal, ocular, aural, anal, and urogenital cavities are described. Data shows the compositions to be effective in reducing influenza A and the human coronaviruses. In that regard, the single-phase multi-component compositions and methods for its antiviral use disclosed herein may be offer a single, effective product to combat multiple, concurrent pandemics.2022-02-10
20220040066ANTIMICROBIAL COMPOSITIONS COMPRISING MODIFIED CLAY AND NONIONIC TRIBLOCK COPOLYMERS - The present invention is in the field of antimicrobial compositions, e.g. for personal care. In particular, the invention relates to antimicrobial compositions for oral care, such as toothpastes, comprising antimicrobial particles and a nonionic triblock copolymer. Accordingly, the present invention relates to antimicrobial compositions comprising a modified clay particle, the particle comprising an antimicrobial compound and a clay particle, and at least one a nonionic triblock copolymer. The invention further relates to the uses and methods of the antimicrobial compositions of the invention.2022-02-10
20220040067MATT-EFFECT COSMETIC COMPOSITION - The invention relates to a composition, notably a cosmetic and/or dermatological composition, in particular for caring for a keratin material, notably the skin and in particular facial skin, which is in the form of an oil-in-water, O/W, emulsion, and comprising at least a) particles of at least one hydrophobic silica aerogel, b) an ester hydrocarbon-based oil, and c) an ether hydrocarbon-based oil, in which said ether and ester oils are present in an ether oil/ester oil weight ratio ranging from 1 to 2.2022-02-10
20220040068HAIR CARE COMPOSITION COMPRISING PYRITHIONE - Disclosed are composite particles comprising a photolabile antidandruff agent and an organic UV filter whose melting point is from 30° C. to 105° C., characterized in that said composite particles comprise a cationic polymer having weight average molecular weight of 1000 Da to 10000000 Da.2022-02-10
20220040069TITANIUM DIOXIDE DISPERSION - The invention provides a dispersion of precursor titanium dioxide particles having an intensity mean peak value particle size, measured by DLS, or a number mean peak value particle size, measured by DLS, in the range from 0.2 to 2.0 μm within a dispersing medium, wherein the particle size distribution of the titanium dioxide particles in dispersion is narrower than the particle size distribution of the precursor titanium dioxide particles. There is also provided the use of the dispersion of titanium dioxide particles to attenuate infrared radiation, particularly in a cosmetic composition, more particularly a cosmetic composition to provide protection against IR radiation, more particularly IRA radiation. There is also provided a personal care composition comprising the titanium dioxide dispersion.2022-02-10
20220040070SKIN LIGHTENING COMPOSTIONS - Disclosed are compositions and methods for their use that include a combination of 2022-02-10
20220040071COSMETIC COMPOSITION FOR KERATIN FIBERS COMPRISING C14-20 FATTY ACID AND SEMICRYSTALLINE POLYMER - The present invention relates to a composition comprising: (2022-02-10
20220040072Reduction of Pathogenic Bacteria Using Arginine - Methods of reducing total pathogenic oral bacteria load within an individual's oral cavity are disclosed. Methods of selectively promoting growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria in a population of bacteria that comprises beneficial oral bacteria and pathogenic oral bacteria, such as in an individual's oral cavity, are disclosed. Methods of selectively promoting growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria in biofilm that comprises beneficial oral bacteria and pathogenic oral bacteria, including biofilm in an individual's oral cavity, are also disclosed, Methods of identifying a compound or composition that enhances the selective promotion of growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria by arginine and methods of identifying a compound or composition that enhances the selective promotion of growth of beneficial oral bacteria relative to growth of pathogenic oral bacteria in biofilm by arginine are disclosed.2022-02-10
20220040073HAIR COLOURING COMPOSITIONS - Disclosed is a hair colouring composition containing amino acids with at least a pKa greater than 10, oxidative dyes, and acetylaspartic acid or salts thereof. The compositions according to the invention do not contain ammonia or ethanolamine, do not damage the hair, guarantee shine and combability, and also cover white hair and withstand blue light.2022-02-10
20220040074Decolorization of Dyed Keratinic Fibers - A multi-component packaging unit (kit-of-parts) for the reductive decolorization of dyed keratinic fibers, which unit includes, packaged separately from one another, 2022-02-10
20220040075PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN UNSATURATED HETEROCYCLIC SALT, AND COMPOSITION COMPRISING SAME - The present invention relates to a cosmetic process for treating keratin materials, in particular keratin fibers, preferably human keratin fibers such as the hair, using a) one or more direct dyes and b) one or more particular heterocyclic salts, to a composition comprising ingredients a) and b) and to a kit comprising a) and b).2022-02-10
20220040076HAIR CARE COMPOSITION - A hair care composition is disclosed comprising from 0.5 to 45% by weight of a salt of acyl glutamate and an anti-dandruff agent of piroctone olamine, wherein the salt of acyl glutamate and the anti-dandruff agent are present in a weight ratio of from 5:1 to 50:1, and wherein the composition does not comprise other anionic surfactants in addition to the salt of acyl glutamate.2022-02-10
20220040077USE OF EVODONE OR A DERIVATIVE THEREOF AS A COOLING AGENT - Use as a cooling agent of a compound of general formula (I)2022-02-10
20220040078SKIN CARE COMPOSITIONS COMPRISING A NON-HYDROLYZED NUCLEIC ACID MATERIAL EXTRACTED FROM TUNA - The present invention relates to a non-therapeutic cosmetic method—for enhancing the overall quality of the skin and for treating aging skin which comprises the use of non-hydrolyzed nucleic acid material extracted from tuna containing more than 75% by weight of DNA salts and less than 1.5 wt % of proteins, and to a non-therapeutic cosmetic composition for topical application onto the skin comprising from 0.01 to 5.0% by weight of said non-hydrolyzed nucleic acid material in a cosmetic or pharmaceutical acceptable carrier.2022-02-10
20220040079RECOMBINANT PROTEINS COMPRISING BOTULINUM TOXIN AND CELL PENETRATING PEPTIDE AND COSMETIC COMPOSITION COMPRISING THEREOF - Disclosed herein is a recombinant protein including botulinum toxin and cell penetrating peptides and cosmetic composition. The cell penetrating peptide according to the present disclosure may be actively used as a topical agent for various disease treatment, aesthetic, or cosmetic purposes, especially for a cosmetic composition, by securing better convenience as well as maximizing the intrinsic in vivo efficacy of the botulinum toxin through the cell penetrating recombinant proteins that combines the botulinum toxin and a cell penetrating peptide by making skin penetration and/or cell penetration for botulinum toxin more efficient.2022-02-10
20220040080PERSONAL CARE COMPOSITION - A personal care composition is provided, comprising: a cosmetically acceptable carrier; a cosmetically acceptable silicone; a modified carbohydrate polymer; wherein the modified carbohydrate polymer comprises a cellulose ether base material functionalized with (i) quaternary ammonium groups, wherein the quaternary ammonium groups and wherein the modified carbohydrate polymer has a Kjeldahl nitrogen content corrected for ash and volatiles, TKN, of 1.0 to 4.0 wt %; and (ii) hydrophobic substituents, wherein the hydrophobic substituents comprise an alkyl group having an average of 10 to 20 carbon atoms; wherein the modified carbohydrate polymer comprises >0.005 to <0.05 moles of the hydrophobic substituents per mole of the cellulose ether base material; wherein the hydrophobic groups are randomly distributed across the backbone of the cellulose ether base material; and wherein the cellulose ether base material has a weight average molecular weight, Mw, of >200,000 Daltons.2022-02-10
20220040081ORGANIC COUNTERANION CO-ASSEMBLY STRATEGY FOR THE FORMATION OF CYCLODEXTRIN-CONTAINING HYBRID FRAMEWORKS - An organic counteranion co-assembly strategy is employed to prepare a hybrid molecular framework. The hybrid molecular framework comprises an ordered arrangement of cyclodextrin (CD), metal cations, and organic anions.2022-02-10
20220040082DETERGENT COMPOSITIONS FOR WASHING URUSHIOL AND METHODS OF TREATING URUSHIOL INDUCED CONTACT DERMATITIS - A composition and a method of washing urushiol off the surface of human skin. The composition includes a first solely C12 surfactant and a second solely C12 surfactant that are each in a non-buffered composition and the composition is free of each of the following: (1) any nonylphenol ethoxylate, (2) any pharmaceutically active drug or prodrug, or (3) any salt that affects the functional characteristics of either of the solely C12 surfactants.2022-02-10
20220040083USE OF COMBRETUM MICRANTHUM EXTRACT IN COSMETICS - Disclosed is a use of 2022-02-10
20220040084BOTANICAL ANTIMICROBIAL COMPOSITION - An antiseptic composition for use as a topical skin sanitizer or as a surface disinfectant includes 2022-02-10
20220040085HYPOALLERGENIC COMPOSITION FOR SKIN REGENERATION OR SKIN SOOTHING, CONTAINING CULTURE PRODUCT OR EXTRACT OF AUREOBASIDIUM PULLULANS STRAIN - Disclosed in the present specification is a hypoallergenic composition for skin regeneration or skin soothing, containing, as an active ingredient, an 2022-02-10
20220040086FORMULATION AND AEROSOL CANISTERS, INHALERS, AND THE LIKE CONTAINING THE FORMULATION - Stable composition of anhydrous micronized ipratropium or a pharmaceutically acceptable anhydrous salt thereof and method of making.2022-02-10
20220040087AUGMENTATION OF PERSONALIZED TUMOR SPECIFIC ADAPTIVE IMMUNITY THROUGH EXTRACORPOREAL REMOVAL OF IMMUNE BLOCKING FACTORS - Disclosed are means, methods and compositions of matter useful for amplification of adaptive immune responses towards neoplastic tissue. In one embodiment, immunization of a patient is performed by a means comprising of administering either an exogenous vaccine or stimulation of immunogenicity of the tumor so as to cause release of antigens/increased exposure of antigens, thus resulting in an “endogenous” vaccine. Subsequent to vaccination a patient is treated by an immunopheresis procedure, in order to allow for removal of “blocking factors” produced by the tumor or produced by cells programmed by tumors to produce said blocking factors. In one embodiment further immunization is performed subsequent to removal of said blocking factors in order to allow for enhancement of adaptive immune responses2022-02-10
20220040088AUGMENTATION OF PERSONALIZED TUMOR SPECIFIC ADAPTIVE IMMUNITY THROUGH EXTRACORPOREAL REMOVAL OF IMMUNE BLOCKING FACTORS - Disclosed are means, methods and compositions of matter useful for amplification of adaptive immune responses towards neoplastic tissue. In one embodiment, immunization of a patient is performed by a means comprising of administering either an exogenous vaccine or stimulation of immunogenicity of the tumor so as to cause release of antigens/increased exposure of antigens, thus resulting in an “endogenous” vaccine. Subsequent to vaccination a patient is treated by an immunopheresis procedure, in order to allow for removal of “blocking factors” produced by the tumor or produced by cells programmed by tumors to produce said blocking factors. In one embodiment further immunization is performed subsequent to removal of said blocking factors in order to allow for enhancement of adaptive immune responses2022-02-10
20220040089STABLE TOPICAL COMPOSITIONS OF FENOLDOPAM - The present disclosure is directed to a topical composition, e.g., a physically and chemically stable topical composition of Fenoldopam comprising about 0.1% to about 5% by weight of Fenoldopam or a pharmaceutically acceptable salt thereof, at least one polyacrylamide-type gelling agent, at least one cellulose-type gelling agent, and at least one solvent, wherein the Fenoldopam is substantially solubilized in the composition, and wherein the composition is stable for at least twelve months at 25° C. and 60% relative humidity.2022-02-10
20220040090Finished Fibrous Structures and Methods of Their Use and Preparation - The disclosure is directed to fibrous structures finished with active pharmaceutical ingredients, as well as methods of their manufacturer and use.2022-02-10
20220040091COMPOSITION FOR SUBMUCOSAL INJECTION AND PREPARATION METHOD THEREOF - The present disclosure provides a composition for submucosal injection including a divalent cation and an oligosaccharide obtained by exposing powdered polysaccharides to irradiation, heat, ultrasound, or ultraviolet radiation. The composition may be provided as a single solution; or the divalent cation and the oligosaccharide may be separately packaged, with the divalent cation being provided in solution form and the oligosaccharide being provided in powder form. The divalent cation may be 0.1-0.5% w/v of Ca2022-02-10
20220040092Ready to use injectable formulations of Micafungin Sodium - The present application provides method for formulating and corresponding a ready-to-use liquid injectable parenteral pharmaceutical composition, comprising Micafungin sodium and a first excipient and/or pharmaceutically acceptable second excipient.2022-02-10
20220040093COMPOSITION FOR USE IN THE TREATMENT OF LESIONS IN THE MUCOSA BY MEANS OF ENDOSCOPIC RESECTION - The present invention relates to a composition, preferably an aqueous pharmaceutical solution, comprising a water-soluble polymer derived from cellulose and hyaluronic acid, preferably comprising carboxymethylcellulose and hyaluronic acid. More specifically, the invention relates to a composition, preferably an aqueous pharmaceutical solution, comprising 0.0001%-5% hyaluronic acid and 0.005%-2% carboxymethylcellulose. The invention also relates to the use of said composition, preferably an aqueous pharmaceutical solution, in the manufacturing of a medicament for the treatment of lesions in the mucosa by means of endoscopic resection, for example, the resection of polyps and/or tumors of the gastrointestinal mucosa.2022-02-10
20220040094DRUG-DEVICE UNIT CONTAINING QUINAGOLIDE - The present invention is based on the identification of a cohort of polyurethane block copolymers that are particularly suited for use in pharmaceutical polymeric drug-device units and which offer improved control of drug release. In particular, there is provided a polymeric drug-device unit comprising a polyurethane block copolymer obtainable by reacting together a poly(alkylene oxide); a difunctional compound; a difunctional isocyanate; and optionally a block copolymer comprising poly(alkylene oxide) blocks; and quinagolide as a pharmaceutically active agent. The drug-device units may find application in the treatment and/or prevention of endometriosis.2022-02-10
20220040095AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS - Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agents and auris pressure modulators. In these methods, the auris compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the immunomodulating and/or auris pressure modulating compositions and formulations onto the auris media and/or auris interna target areas, or via perfusion into the auris media and/or auris interna structures.2022-02-10
20220040096AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS - Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agents and auris pressure modulators. In these methods, the auris compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the immunomodulating and/or auris pressure modulating compositions and formulations onto the auris media and/or auris interna target areas, or via perfusion into the auris media and/or auris interna structures.2022-02-10
20220040097CHEWABLE TABLET - A chewable tablet formulation includes an active material comprising an active agent in a maltodextrin base and an inactive material comprising a sugar, rice bran, carnauba wax, maltodextrin and a flavoring agent.2022-02-10
20220040098METHODS FOR TREATING RESPIRATORY VIRAL INFECTIONS - Disclosed is a method of treating a subject for a respiratory viral infection. The method comprises administering to the subject by inhalation an effective amount of a hypertonic saline solution comprising an ibuprofenate salt.2022-02-10
20220040099INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST A BASAL INSULIN WHICH PI IS COMPRISED BETWEEN 5.8 AND 8.5 AND A COPOLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS - A physically stable composition in the form of an injectable aqueous solution, wherein the pH is from 6.0 to 8.0, including at least: a) a basal insulin which isoelectric point (pI) is from 5.8 and 8.5 and b) a copolyamino acid according to formula I:2022-02-10
20220040100Stable Acyclovir Sodium Parenteral Formulation - The present application provides method for formulating and corresponding liquid parenteral formulations that include a desired amount of acyclovir sodium added to a vessel with a pharmaceutically acceptable infusion diluent, which are stirred to provide a shelf stable injectable solution.2022-02-10
20220040101STABILISED HYPOCHLOROUS SOLUTIONS AND THEIR MEDICAL COSMETIC USES - A stabilised hypochlorous solution is disclosed. The solution includes hypochlorous acid (HOCl), hypochlorite (ClO—), and chlorine (Cl—) that combine to provide a total chlorine concentration. The total chlorine concentration is at or below 300 ppm, the hypochlorous acid, measured by UV spectroscopy at 230 nm, is the predominant species, the hypochlorite, measured by UV spectroscopy at 290 nm, is present at significantly lower levels than that of the hypochlorous acid, such that a ratio of hypochlorous acid to hypochlorite is greater than 7.5:1. The solution has a pH of between about 7 and 4 and a shelf life of at least 12 months, at 22° C., such that the amount of hypochlorous present remains at above 80% of its starting concentration, and the pH remains above 4.2022-02-10
20220040102Solid Solution Compositions and Use in Chronic Inflammation - The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.2022-02-10
20220040103EMULSION FORMULATIONS OF MULTIKINASE INHIBITORS - Compositions comprising a therapeutically effective amount of a multikinase inhibitor, such as nintedanib or axitinib or pazopanib, are provided, wherein the composition is an emulsion, such as a nanoemulsion, with lipophilic carrier (e.g., castor oil), a polyoxyl oil (e.g., polyolyl-35 castor oil), optionally with a surfactant (e.g., polysorbate 80), optionally with a cyclic oligosaccharide, such as a cyclodextrin (e.g., 2-hydroxypropyl-beta-cyclodextrin), as a solubilizer. Methods for treating ocular conditions with the compositions are also provided.2022-02-10
20220040104NANOLIPOSOME-MICROBUBBLE CONJUGATE INCLUDING DRUG FOR HAIR LOSS TREATMENT ENCAPSULATED IN NANOLIPOSOME AND COMPOSITION FOR ALLEVIATING OR TREATING HAIR LOSS CONTAINING SAME - Provided are a nanoliposome-microbubble conjugate in which a drug for hair loss treatment such as finasteride, minoxidil, dutasteride, etc. is encapsulated in a nanoliposome and a composition for alleviating or treating hair loss containing the same. Since an orally administered agent such as finasteride, currently useful as a drug for hair loss treatment, causes side effects, drug delivery through scalp application is most desirable, but the drug is not delivered to hair follicle cells through scalp application alone. Since a drug for hair loss treatment useful as an external preparation for skin causes various side effects, the concentration thereof that is used needs to be further lowered. The above nanoliposome-microbubble conjugate is capable of increasing the delivery efficiency of a drug for hair loss treatment at a low concentration, and is thus very effective at treating androgenic alopecia.2022-02-10
20220040105NANOLIPOSOME-MICROBUBBLE CONJUGATE INCLUDING DRUG FOR HAIR LOSS TREATMENT ENCAPSULATED IN NANOLIPOSOME AND COMPOSITION FOR ALLEVIATING OR TREATING HAIR LOSS CONTAINING SAME - Provided are a nanoliposome-microbubble conjugate in which a drug for hair loss treatment such as finasteride, minoxidil, dutasteride, etc. is encapsulated in a nanoliposome and a composition for alleviating or treating hair loss containing the same. Since an orally administered agent such as finasteride, currently useful as a drug for hair loss treatment, causes side effects, drug delivery through scalp application is most desirable, but the drug is not delivered to hair follicle cells through scalp application alone. Since a drug for hair loss treatment useful as an external preparation for skin causes various side effects, the concentration thereof that is used needs to be further lowered. The above nanoliposome-microbubble conjugate is capable of increasing the delivery efficiency of a drug for hair loss treatment at a low concentration, and is thus very effective at treating androgenic alopecia.2022-02-10
20220040106TAILORED HYPOIMMUNE NANOVESICULAR DELIVERY SYSTEMS FOR CANCER TUMORS, HEREDITARY AND INFECTIOUS DISEASES - Hypoimmunogenic induced pluripotent stem cell (iPSC)-derived biomimetic nanovesicles (Hypo-BioNVs) or Hypo-exosomes including tailored chimeric antigen receptor (CARs) which can recognize target biomarkers through an antibody fragment scFV region, bifunctional or ByTE antibodies, by a viral epitope recognition receptor (VERR), V2022-02-10
20220040107COMPOSITIONS AND METHODS FOR TOPICAL DELIVERY - Compositions comprising an active agent and a decoy molecule and methods for treating pain by topically administering such compositions are described herein. The compositions may be powdered. Compositions include a decoy molecule with a specified average molecular weight and no high molecular weight decoy molecule. The extracellular components include hyaluronic acid, collagen, fibronectin, elastin, lectin, and fragments thereof and combinations thereof.2022-02-10
20220040108LIGHT UPCONVERSION SILICA PARTICLES - A composition, method, and article of manufacture are disclosed. The composition and the article of manufacture include a silica particle and light upconversion molecules incorporated into the silica particle. The method includes obtaining sidechain-modified light upconversion molecules, and incorporating the sidechain-modified light upconversion molecules into a silica particle to form a light upconversion particle.2022-02-10
20220040109KIDNEY-TARGETING DRUG DELIVERY CARRIER - The present invention relates to a compound having a macromolecular carrier having a plurality of terminal groups, wherein the carbonyl group of serine is linked by a peptide bond or an ester bond directly or via a linker to the terminal groups, a carrier for drug delivery composed of the compound, and a medicament for preventing or treating renal diseases, containing the carrier for drug delivery and a drug bonded to the carrier directly or via a linker or encapsulated therein. According to the present invention, a carrier for drug delivery that is selectively accumulated in kidney in vivo can be provided.2022-02-10
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