| 06th week of 2012 patent applcation highlights part 46 |
| Patent application number | Title | Published |
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| 20120035357 | PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC - The present invention relates to an improved process for the preparation of the carbapenem antibiotic of formula (I) or its salts, hydrates and esters. The present invention further provides novel crystalline form of compound of general formula (III), wherein R | 2012-02-09 |
| 20120035358 | Molecular transporter compositions comprising dendrimeric oligoguanidine with a tri-functional core that facilitates delivery into cells in vivo - Novel molecular transporter compositions and their use for transporting bioactive substances into cells in living animals are disclosed. To afford in vivo delivery, the composition is covalently linked to the bioactive substance and the resultant composite structure is introduced into the subject. The transporter composition includes multiple guanidine moieties on a dendrimeric scaffold having a tri-functional core. The tri-functional core is a phosphorodiamidate or phosphoramide moiety. | 2012-02-09 |
| 20120035359 | PHENOXAZINE DERIVATIVES AND METHODS OF USE THEREOF - The present invention encompasses phenoxazine derivatives and methods of use thereof. | 2012-02-09 |
| 20120035360 | DUAL-COLOR IMAGING METHOD OF SODIUM/CALCIUM ACTIVITIES USING TWO-PHOTON FLUORESCENT PROBES AND PREPARATION METHOD OF TWO-PHOTON FLUORESCENT PROBES - Provided are a method for dual-color imaging of sodium/calcium activities using a two-photon fluorescent probe and a method for preparing the two-photon fluorescent probe. The disclosed two-photon fluorescent probe for detecting calcium ions near the cell membrane reacts with calcium cations to exhibit strong two-photon fluorescence and may be selectively and easily loaded into the cell membrane by forming a complex with a calcium ion. Further, it allows imaging of the distribution of calcium cations in a living cell or tissue since it can selectively detect calcium ions in the living cell or tissue at a depth of 100 to 200 μm for more than 60 minutes. In addition, by staining the living cell or tissue with two probes of different fluorescent colors, the calcium and sodium activities can be imaged simultaneously at different channels. | 2012-02-09 |
| 20120035361 | SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1/GLAST) - The invention is the discovery of the use of the class of compounds represented by Formula I, as selective inhibitors of excitatory amino acid transporter (EAAT) subtype 1 (EAAT1) and its rodent ortholog L-glutamate/L-aspartate transporter (GLAST) for the study of function and distribution of EAAT1/GLAST in the central nervous system and studies of the physiological and pathological functions of the EAAT1/GLAST subtype in native tissues, cultured neurons, and/or animal models for CNS disorders. | 2012-02-09 |
| 20120035362 | PHOSPHORAMIDITE DERIVATIVES OF FOLIC ACID - The present invention provides for compounds of Formula I: | 2012-02-09 |
| 20120035363 | CRYSTALLINE 4-(3-CHLORO-2-FLUOROANILINO)-7 METHOXY-6-... - 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline difumarate, pharmaceutical compositions containing the difumarate, the use of the difumarate in the treatment of hyperproliferative disorders such as cancer and processes for the manufacture of the difumarate are described. | 2012-02-09 |
| 20120035364 | TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME - A tetrathiafulvalene derivative expressed by General Formula (I): General Formula (I) in General Formula (I), X represents an atom selected from a carbon atom, a sulfur atom, and a nitrogen atom, and Xs may be the same or different; provided that when X is the carbon atom or the nitrogen atom, R | 2012-02-09 |
| 20120035365 | Method for Manufacturing Porous Materials from Waste PET Bottle - A method for manufacturing porous material from waste PET bottle, the method comprising: providing transition metal or d | 2012-02-09 |
| 20120035366 | N-Demethylation of 6-Keto Morphinans - The present invention provides processes for the demethylation of an N-methyl morphinan comprising a ketone functional group. In particular, the invention provides methods for the protection of the ketone functional group such that impurities are not generated during the demethylation of the N-methyl morphinan. | 2012-02-09 |
| 20120035367 | Tandem Process for Preparing N-Alkyl Morphinans - The present invention provides processes for the preparation of N-alkyl morphinans without the isolation of nor-morphinan intermediates. In particular, the invention provides tandem hydrolysis/alkylation reactions for the synthesis of N-alkyl morphinans. | 2012-02-09 |
| 20120035368 | PROCESS FOR THE PREPARATION OF PYRIDO[2,1-a] ISOQUINOLINE DERIVATIVES - The present invention relates to a novel process for the preparation of pyrido[2,1-a]isoquinoline derivatives of the formula | 2012-02-09 |
| 20120035369 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE - The problem to be solved is to provide an important intermediate for production of an FXa inhibitor. The solution thereto is a method for industrially producing a compound (1) or a compound (4), comprising: [Step 1]: adding a quaternary ammonium salt and a metal azide salt to water to prepare an aqueous solution of an azidification reagent complex comprising quaternary ammonium salt-metal azide salt, and subsequently dehydrating the aqueous solution using an aromatic hydrocarbon solvent to form a mixed solution of the azidification reagent complex comprising quaternary ammonium salt-metal azide salt and the aromatic hydrocarbon solvent with a water content of 0.2% or less; and [Step 2]: adding, to the mixed solution prepared in [Step 1], a compound (2) wherein L represents a leaving group. | 2012-02-09 |
| 20120035370 | Azaindazole Compounds As CCR1 Receptor Antagonists - Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. | 2012-02-09 |
| 20120035371 | PROCESS FOR THE MANUFACTURE OF NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND INTERMEDIATES THEREOF - The current invention describes novel chiral synthetic routes and intermediates for the manufacture of chiral anti-inflammatory agents of general formula VIII | 2012-02-09 |
| 20120035372 | METHOD FOR PRODUCING 2-HALOGENO-6-SUBSTITUTED-4-TRIFLUOROMETHYLPYRIDINE - The present invention relates to a process of a process for producing a 2-halogeno-6-substituted-4-trifluoromethylpyridine. Specifically, the present invention provides a process for producing a 2-halogeno-6-substituted-4-trifluoromethylpyridine represented by the formula (I): | 2012-02-09 |
| 20120035373 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES - The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products. | 2012-02-09 |
| 20120035374 | PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF - The present invention relates to an improved process for the preparation of fluvastatin or pharmaceutical acceptable salts or derivatives thereof, in particular to a one-pot process for large scale production of Fluvastatin and salts thereof in high yield and high purity and pharmaceutical preparations containing said compounds. | 2012-02-09 |
| 20120035375 | DI-TIN FUSED THIOPHENE COMPOUNDS AND POLYMERS AND METHODS OF MAKING - Di-tin fused thiophene (FT) compounds, FT polymers, such as of the formula -{-(FTx)-(Ar) | 2012-02-09 |
| 20120035376 | METHODS FOR THE MANUFACTURE OF ACETALS AND KETALS, AND THE ACETALS AND KETALS PRODUCED THEREBY - A method for producing a product that comprises glycerol ketal of ethyl levulinate or propylene glycol ketal of ethyl levulinate comprises reacting either glycerol or propylene glycol with ethyl levulinate in the presence of a homogenous or heterogeneous catalyst system in a reactor system. The ethyl levulinate and either glycerol or propylene glycol are heated to remove water, polyol, and excess ethyl levulinate. The excess ethyl levulinate and polyol is recycled back to the reactor. The product is distilled in a specific fashion and optionally treated by means of a stabilizing agent or acid species removal bed, to obtain a composition comprising glycerol ketal of ethyl levulinate or propylene glycol ketal of ethyl levulinate wherein the composition comprises less than or equal to about 2 wt % contaminants. | 2012-02-09 |
| 20120035377 | ORGANOPHOSPHORUS COMPOUNDS, CATALYTIC SYSTEMS COMPRISING SAID COMPOUNDS AND METHOD OF HYDROCYANATION OR OF HYDROFORMYLATION USING SAID CATALYTIC SYSTEMS - Organophosphorus compounds, catalytic systems comprising a metallic element forming a complex with the organophosphorus compounds and methods of hydrocyanation and of hydroformylation employed in the presence of the catalytic systems are described. | 2012-02-09 |
| 20120035378 | HYDROGENATION PROCESS FOR THE PREPARATION OF TETRAHYDROFURAN AND ALKYLATED DERIVATIVES THEREOF - A process is provided for the synthesis of tetrahydrofuran and related compounds by hydrogenation of furan and derivatives, using a sponge nickel catalyst that has been promoted with iron and chromium. | 2012-02-09 |
| 20120035379 | METHOD FOR PREPARING TAXANE DERIVATIVES - Provided is a method for preparing a taxane derivative, comprising: carrying out condensation of a phenylisoserine derivatives having a protective group introduced thereto or a mixture of isomers thereof, as a side chain, with a baccatin III derivative or 10-deacetyl-baccatin III derivative to obtain a mixture of isomers; separating the isomers via chromatography; and carrying out a reversion of the stereochemical structure of a selectively separated isomer, which is suitable for producing a taxane derivative in a large scale with high yield. | 2012-02-09 |
| 20120035380 | PROCESS FOR PREPARING EPICHLOROHYDRIN FROM GLYCEROL - A process for preparing epichlorohydrin includes chlorinating glycerol with gaseous hydrogen chloride in a bubble column, by supplying hydrogen chloride, glycerol and a mixture of monochloropropanediol and residues of glycerol recycled from the distillation units connected downstream of the bubble column, dichloropropanol and residues to the bottom of the bubble column, and, close to the top of the bubble column, drawing off the mixture of monochloropropanediol, dichloropropanol, water, residues of glycerol and residues formed there and feeding it to at least one distillation unit, after which the dichloropropanol and water distilled off there are hydrolyzed with sodium hydroxide solution. Unconverted hydrogen chloride drawn off from the top of the bubble column is absorbed with freshly supplied glycerol in a scrubber, and this hydrogen chloride-containing glycerol is supplied at the bottom of the bubble column. Preference is given to increasing the conversion rate by using oxalic acid as a catalyst. | 2012-02-09 |
| 20120035381 | PROCESS FOR PREPARING ALLYL ALCOHOL ALKOXYLATES - A process for preparing polyether alcohols by reacting one or more unsaturated starters having at least one active hydrogen atom per molecule with one or more alkylene oxides in the liquid phase in the presence of a basic catalyst in a reactor, wherein the one or more alkylene oxides are introduced into the reactor in such a way that the concentration of unreacted alkylene oxide in the liquid reaction mixture in the reactor is increased as far as possible with increasing degree of addition of the alkylene oxide onto the starter, with the proviso that the temperature at the end of a runaway reaction is at any point in time at least 100 K below the onset temperature of the decomposition reaction of the liquid reaction mixture, is proposed. | 2012-02-09 |
| 20120035382 | METHOD FOR SEPARATION AND PARTIAL RETURN OF RHODIUM AND CATALYTICALLY EFFECTIVE COMPLEX COMPOUNDS THEREOF FROM PROCESS STREAMS - The invention relates to a method for separating and partially returning transition metals and/or catalytically effective complex compounds thereof from a reaction mixture by combining one at least one-stage membrane separation and an adsorption, wherein a current comprising a catalyst, comprising a transition metal, is divided over at least one one-stage membrane separation step in a transition metal enriched retentate stream that resupplies the reaction mixture and a transition metal depleted permeate stream and the transition metal depleted permeate stream is further supplied to an adsorption step. The invention further relates to a method for producing tridecanals. | 2012-02-09 |
| 20120035383 | ALKOXYLATION PROCESSES AND CATALYSTS THERFOR - A process of contacting an alkylene oxide with 2-methoxy-1-propanol (PM1) in the presence of an oligomeric Schiff base metal complex catalyst is disclosed. Further, a process involving contacting an alkylene oxide with an alkyl alcohol using an oligomeric Schiff base metal complex as a catalyst is also disclosed. Additionally, novel compositions which can be used as catalysts in processes involving the contacting of an alkyl alcohol with an alkylene oxide are also disclosed. | 2012-02-09 |
| 20120035384 | ALUMINUM OXYCARBIDE COMPOSITION AND PRODUCTION METHOD THEREFOR - Provided is an aluminum oxycarbide composition production method capable of increasing a yield of Al | 2012-02-09 |
| 20120035385 | SELECTING CATALYST AND CONDITIONS - A method to form an asymmetric silicone copolymer, comprises effecting a monoselective hydrosilylation reaction between a dihydridosiloxane and a first aliphatically unsaturated compound in the presence of a precious metal hydrosilylation catalyst to form a reaction product comprising substantial monohydridosiloxane; and hydrosilylating the monohydridosiloxane with another different aliphatic unsaturated compound to form an asymmetric silicone copolymer. | 2012-02-09 |
| 20120035386 | METHOD FOR PREPARATION OF AND COMPOSITIONS OF LOW FOAM, NON-GELLING, SURFACTANTS - Low foam, non-gelling surfactants include certain non-ionic alcohol ethoxylate surfactants and anionic ether sulfate surfactants formed therefrom, and processes for preparing the same. Also included are agricultural formulations including agriculturally active ingredients in combination with certain anion ether sulfate surfactants. | 2012-02-09 |
| 20120035387 | HYDROCYANATION OF 2-PENTENENITRILE - The invention provides a process for hydrocyanation, comprising: contacting 2-pentenenitrile with hydrogen cyanide at a temperature in the range of about 0° C. to about 150° C. in the presence of at least one Lewis acid promoter and a catalyst precursor composition, wherein the catalyst precursor composition comprises a zero-valent nickel and at least one bidentate phosphite ligand selected from a member of the group represented by Formula I and Formula II, in which all like reference characters have the same meaning, except as further explicitly limited: | 2012-02-09 |
| 20120035388 | PLATINUM/CARBON NANOTUBE CATALYST, THE PREPARATION PROCESS AND USE THEREOF - This invention provides a platinum/carbon nanotube catalyst applicable to heterogeneous asymmetric hydrogenation, which is fabricated by supporting platinum on carbon nanotube carriers. The catalyst is prepared by the steps of: heating purified carbon nanotubes in nitric acid, filtering and washing the same with water until pH value of the filtrate becomes neutral, drying the carbon nanotubes; immersing the carbon nanotube carriers obtained in an aqueous chloroplatinic acid solution and carrying out ultrasonic treatment at room temperature; immersing the mixture of the carbon nanotubes and the aqueous chloroplatinic acid solution under stirring; drying the material by heating to 110° C. from room temperature and maintaining this temperature; grinding the product to fine powders, reducing the fine powders with an aqueous sodium formate solution under a heating condition, filtering and washing the product with deionized water, and drying the product. The invention further provides a process for preparing a platinum/carbon nanotube catalyst and a use thereof in heterogeneous asymmetric hydrogenation. | 2012-02-09 |
| 20120035389 | METHOD FOR PURIFYING THE AZEOTROPIC FRACTION GENERATED DURING THE SYNTHESIS OF N,N-DIMETHYL AMINOETHYL ACRYLATE - The invention relates to a method for producing N,N-dimethylaminoethyl acrylate by the transesterification reaction of an alykl acrylate by N | 2012-02-09 |
| 20120035390 | Ethyl acetate production - A process for the production of high purity ethyl acetate from ethanol is described. The process involves reacting ethanol over a suitable catalyst in a reactive distillation column. The reactive distillation setup allows overcoming the reaction equilibrium for increased conversion of ethanol. Hydrogen is removed as the distillate and ethyl acetate is obtained as a bottoms product from the reactive distillation column. A feed of hydrogen at the bottom of the column and a suitable hydrogenation catalyst placed at the bottom of the column allows for a significant reduction of impurities such as butan-2-one, butyraldehyde in the ethyl acetate product. Adding side reactors to the reactive distillation column allows additional catalyst holdup for improved reactant conversion. | 2012-02-09 |
| 20120035391 | PROCESS FOR THE PREPARATION OF POLYISOCYANATES AND USE THEREOF - The invention relates to a process for isocyanate modification which includes reacting a) at least one organic isocyanate having an NCO functionality greater than or equal to 1, b) a catalyst comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation, c) optionally a solvent, and d) optionally additives. The present invention also relates to a catalyst for isocyanate modification comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation. | 2012-02-09 |
| 20120035392 | TUBULAR FLOW TYPE REACTOR - A tubular flow type reactor comprising: (1) inflow channels for respective inflow of at least two kinds of fluids to be used in a reaction, (2) an outer tube having a lumen that is capable of merging the fluids and of distributing the merged fluids for the reaction, (3) an outflow channel for outflow of a reaction product from the outer tube, and (4) an inner tube disposed in the lumen of the outer tube, wherein an annular flow channel is formed between the outer tube and the inner tube, and the inflow channels are connected to the outer tube along the direction tangential to the internal circumference of the outer tube in such a manner that the lumens of the inflow channels communicate with the lumen of the outer tube, i.e., the annular flow channel. | 2012-02-09 |
| 20120035393 | METHOD FOR PRODUCING ALIPHATIC CARBOXYLIC ACIDS FROM ALDEHYDES BY MICROREACTION TECHNOLOGY - A process for preparing aliphatic carboxylic acids having 3 to 10 carbon atoms by oxidizing the corresponding aldehydes with oxygen or oxygen-containing gases, characterized in that (i) the oxidation is performed in a microreactor at elevated pressure and with an oxygen excess based on the stoichiometrically required amount of oxygen, and (ii) in that the reaction mixture removed from the microreactor is passed through at least one postreactor without further addition of oxygen, and (iii) wherein the oxidation reaction in the microreactor is performed under such conditions that aldehyde and corresponding peracid formed are present in the reaction mixture removed in a molar ratio within a range of | 2012-02-09 |
| 20120035394 | PROCESS FOR THE RECOVERY OF BETAINES FROM ELECTRODIALYSIS WASTE STREAMS - The present invention discloses a process for the recovery of betaines from electrodialysis (ED) waste streams, whereby said waste streams are treated with a pressure driven membrane process. | 2012-02-09 |
| 20120035395 | PROCESS FOR PRODUCING PHTHALIC ACID COMPOUND INCLUDING CHLORINATED AROMATIC RING - Provided is a process for producing a phthalic acid compound whose aromatic ring has been chlorinated, the process reacting a phthalic acid compound and chlorine in a mixture of chlorosulfonic acid and thionyl chloride in the presence of an iodine compound. | 2012-02-09 |
| 20120035396 | PROCESS FOR PREPARING MDA VIA THE STAGE OF THE AMINAL - The invention relates to a process for preparing methylenediphenyldiamine (MDA), comprising the following steps a) to c):
| 2012-02-09 |
| 20120035397 | PROCESS FOR THE HYDROXYLATION OF PHENOLS AND OF PHENOL ETHERS - A process for the hydroxylation of phenols and of phenol ethers by hydrogen peroxide is described. More particularly a process for the hydroxylation of phenol by hydrogen peroxide is described. The described process can include hydroxylation of a phenol or of a phenol ether having at least one hydrogen atom at the ortho and para position of the hydroxyl group or of the ether group, by reaction of said phenol or phenol ether, with hydrogen peroxide, in the presence of an acid catalyst, wherein the reaction is carried out in the presence of an effective amount of a catalyst which is a mixture of at least two strong acids and wherein one of the acids is chosen from strong protonic acids and the other acid is chosen from superacids. | 2012-02-09 |
| 20120035398 | PROCESS TO REMOVE PRODUCT ALCOHOL FROM A FERMENTATION BY VAPORIZATION UNDER VACUUM - A fermentation liquid feed including water and a product alcohol and optionally CO | 2012-02-09 |
| 20120035399 | METHOD FOR PRODUCING 1,6-HEXANEDIOL BY HYDROGENATION OF OLIGO- AND POLYESTERS - The present invention relates to a process for hydrogenating oligo- and/or polyesters obtainable by esterifying a DCS with a diol or diol mixture, said hydrogenation being performed in the presence of a catalyst whose catalyst precursor comprises copper oxide, aluminum oxide and at least one oxide of lanthanum, of iron, of tungsten, of molybdenum, of titanium or of zirconium, and to a process for preparing 1,6-hexanediol by catalytically hydrogenating ester mixtures which comprise, as main components, oligo- and polyesters of adipic acid and 6-hydroxycaproic acid, and are obtained by esterifying DCS with diols, especially 1,6-hexanediol or diol mixtures. | 2012-02-09 |
| 20120035400 | PROCESS FOR PURIFYING ETHANOL - In one embodiment, the invention is to a process for producing ethanol. The process comprises the step of hydrogenating an acetic acid feed stream in a first reactor to form a crude ethanol product. The crude ethanol product may comprise, among other components, ethanol, acetaldehyde, and residual acetic acid. The process further comprises the step of recovering acetaldehyde from the crude ethanol product. The process further comprises the steps of feeding a first portion of the recovered acetaldehyde to the first reactor and reacting the first portion of the recovered acetaldehyde in the first reactor to form additional ethanol. In addition, the inventive process may comprise the steps of feeding a second portion of the recovered acetaldehyde to a second reactor and reacting the second portion of the recovered acetaldehyde in the second reactor to faun an additional product. | 2012-02-09 |
| 20120035401 | Pelletized Low Molecular Weight Brominated Aromatic Polymer Compositions - Novel polymer compositions of specified formula are converted into pellets of this invention by process technology provided by this invention. By forming a binder free melt of a polymer of such polymer compositions, and converting the melt into pellets as described here-in, pellets can be formed produce during production, handling, and use, no more than acceptably small amounts of “fines” or air-entrainable dusts. | 2012-02-09 |
| 20120035402 | METHODS OF MAKING CHLORINATED HYDROCARBONS - Methods for the manufacture of 1,1,1,2,3-pentachloropropane from 1,1,1,3-tetrachloropropane and chlorine are disclosed. Improved methods are provided for the manufacture of 1,1,2,3-tetrachloropropene from 1,1,1,2,3-pentachloropropane. Methods are also disclosed for the manufacture of 1,1,2,3-tetrachloropropene from 1,1,1,3-tetrachloropropane and chlorine and for the manufacture of 1,1,2,3-tetrachloropropene from carbon tetrachloride, ethylene, and chlorine. | 2012-02-09 |
| 20120035403 | CONVERTING BIOMASS TO GASEOUS FUEL HYDROCARBONS - A method includes providing a solution containing a C | 2012-02-09 |
| 20120035404 | HYDROCARBONS FROM PYROLYSIS OIL - The present invention relates to a process for converting pyrolysis oil obtained by pyrolysis of biomass into fuel range hydrocarbon by alcoholysis of pyrolysis oil with subsequent hydrotreatment. The current invention provides straightforward methodology to prepare upgradable pyrolysis oil via alcoholysis. The invention uses hydrotreating technology for oxygen removal and hydrocarbon production. The resulting hydrocarbon products are 100% fungible with conventional transportation fuels. | 2012-02-09 |
| 20120035405 | METHOD FOR ENHANCED GAS HYDRATE PERMEABILITY - The present invention relates to an improved method for recovering hydrocarbons trapped in hydrate formations. | 2012-02-09 |
| 20120035406 | DEHYDRATION OF LIQUID FUEL - A method for dehydrating liquid fuel, the method comprising injecting a supply of dry gas into a liquid fuel via an outlet submerged in the liquid fuel. Also, a system for dehydrating liquid fuel, the system comprising a container for storing a liquid fuel, a line for delivering a supply of dry gas, and an outlet disposed near the bottom of the container and connected to the gas line for injecting dry gas into the liquid fuel. | 2012-02-09 |
| 20120035407 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 2012-02-09 |
| 20120035408 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 2012-02-09 |
| 20120035409 | BI- AND TRICYCLIC INDAZOLE-SUBSTITUTED 1,4-DIHYDROPYRIDINE DERIVATIVES AND USES THEREOF - This invention relates to novel bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 2012-02-09 |
| 20120035410 | SYSTEMS AND METHODS FOR THE TREATMENT OF PELVIC DISORDERS INCLUDING MAGNETIC PARTICULATES - Systems and methods of localizing or delivery cells, biologics and/or drugs to a specific target area to treat pelvic health disorders are provided. A treatment composition including cells, biologics and/or drugs are associated with magnetic particulates, and the positioning of these materials is facilitated through use of a magnetic field-generating device that is configured to be placed on or into a pelvic anatomical structure. Certain embodiments directed to the treatment of ED in male patients can include a cell based therapy system. | 2012-02-09 |
| 20120035411 | STABILIZING DRIVE FOR CONTACTLESS ROTARY BLOOD PUMP IMPELLER - A rotary blood pump includes a casing defining a pumping chamber. The pumping chamber has a blood inlet and a tangential blood outlet. One or more motor stators are provided outside of the pumping chamber. A rotatable impeller is within the pumping chamber and is adapted to cause blood entering the pumping chamber to move to the blood outlet. The impeller has one or more magnetic regions. The impeller is radially constrained in rotation by magnetic coupling to one or more motor stators and is axially constrained in rotation by one or more hydrodynamic thrust bearing surfaces on the impeller. | 2012-02-09 |
| 20120035412 | METHOD FOR CONNECTING A BLOOD PUMP WITHOUT TRAPPING AIR BUBBLES - A method for connecting medical tubing or any other type of fluidic circuit conduits (e.g., cannulae) to a ventricular assist device (“VAD”) or any other pumping device used for blood pumping during cardiac circulatory support for vascular surgery. The method prevent air bubbles from entering a cardiac circulatory support system when connecting cannulae to a VAD that may later enter the blood stream of a patient during cardiac surgery, and also provide for purging any air bubbles that may have entered the cardiac circulatory support system during a cannulae-VAD connection. | 2012-02-09 |
| 20120035413 | SYSTEM FOR CONNECTING A BLOOD PUMP WITHOUT TRAPPING AIR BUBBLES - A system for connecting medical tubing or any other type of fluidic circuit conduits (e.g., cannulae) to a ventricular assist device (“VAD”) or any other pumping device used for blood pumping during cardiac circulatory support for vascular surgery. The system prevents air bubbles from entering a cardiac circulatory support system when connecting cannulae to a VAD that may later enter the blood stream of a patient during cardiac surgery, and also provide for purging any air bubbles that may have entered the cardiac circulatory support system during a cannulae-VAD connection. | 2012-02-09 |
| 20120035414 | CONTOURED ELASTOMERIC BARRIER FOR BOWEL RETENTION AND METHOD OF USE - The invention provides a device for bowel packing having an essentially elliptical shape that is essentially symmetrical along a minor axis of the ellipse, and the device includes a notch located on the minor axis below the major axis. The device is composed of material comprising an elastomeric polymer and the device is appropriately sized for retaining the intestines of a mammal. The invention further provides methods of use of the devices of the invention for bowel packing. The invention further provides methods for increasing bowel packing speed, increasing effectiveness of bowel retention, decreasing the formation of post-operative intraperitoneal adhesions, and increasing temperature of the abdominal cavity during surgery by use of the device. | 2012-02-09 |
| 20120035415 | CLAMPING SYSTEM - A collet comprising a cylindrical body comprising a first end and a second end and an aperture coaxial within the cylindrical body. The aperture is configured for receiving a medical device and for securing the medical device by decreasing in diameter when pressure is applied to at least one of the first end and the second end of the cylindrical body. | 2012-02-09 |
| 20120035416 | Medical Devices and Methods - The present invention relates generally to medical devices and methods. The present medical devices comprises a platform comprising a magnetically-attractive material, and a camera coupled to the platform and configured to be moved in at least three degrees of freedom relative to the platform, where the camera's movement in each respective degree of freedom is controlled by a separate actuator coupled to the platform. The medical devices further comprise a housing disposed around at least a portion of the camera, the housing being at least partially transparent, and a wiper arm configured to move relative to the housing. Some embodiments of the present multi-degree-of-freedom cameras for a medical procedure, comprises a platform comprising a magnetically-attractive material, an apparatus to moving the platform within a body cavity of a patient when the apparatus is outside the body cavity, the apparatus comprising a magnetic assembly, and a camera coupled to the platform, and configured to be moved in at least three degrees of freedom relative to the platform, where the camera's movement in each respective degree of freedom is controlled by a separate actuator coupled to the platform. | 2012-02-09 |
| 20120035417 | Method and device for irrigation of body cavities - A pressure and a vision regulation method and device for irrigation of a body cavity ( | 2012-02-09 |
| 20120035418 | IMAGING SENSOR WITH THERMAL PAD FOR USE IN A SURGICAL APPLICATION - A system, apparatus and methods for providing a single use imaging device having thermal and electrical safeguards for sterile environments is disclosed and described. A single use high definition camera used for general purpose surgical procedures including, but not limited to: arthroscopic, laparoscopic, gynecologic, and urologic procedures, may comprise an imaging device that is a sterile and designed to ensure single use. The imaging device may further include a thermal pad that is thermally conductive, but relatively electrically insulating. | 2012-02-09 |
| 20120035419 | ELECTRONIC ENDOSCOPE SYSTEM - An electronic endoscope system is composed of an electronic endoscope, a light source apparatus, and a temperature converter. The electronic endoscope has a CMOS sensor in a distal portion of an insert section to be inserted into a patient's body cavity. Illumination light from the light source apparatus is applied to the body cavity through the distal portion. The temperature converter obtains an average pixel value of an optical black (OB) region out of an imaging signal from the CMOS sensor, and converts the average OB pixel value into a temperature of the CMOS sensor on a frame-by-frame basis with the use of data in a temperature conversion table. The table represents a relationship between the average OB pixel value and the temperature of the CMOS sensor. Light quantity of the illumination light is adjusted in accordance with the temperature of the CMOS sensor to prevent deterioration of image quality. | 2012-02-09 |
| 20120035420 | Endoscope with adjustable viewing angle - An endoscope with adjustable viewing angle includes a pivotable prism (to divert light that can pivot around a pivot axis to adjust the viewing angle and a fixed prism to divert light that is diverted by the pivotable prism into a direction parallel to the longitudinal axis of the endoscope, such that at least either a light outlet surface of the pivotable prism is positioned in a recess of the fixed prism or a light inlet surface of the fixed prism is positioned in a recess of the pivotable prism. | 2012-02-09 |
| 20120035421 | ENDOSCOPE WITH ADJUSTABLE VIEWING ANGLE - An endoscope with adjustable viewing angle, in which the viewing angle can pivot around a pivot axis, includes a fixed reflecting surface for reflecting illuminating light from a direction parallel to the longitudinal axis of the endoscope to a direction parallel to the pivot axis of the viewing angle and a pivotable reflecting surface for reflecting illuminating light from a direction parallel to the pivot axis of the viewing angle to the viewing angle for illuminating an object observed by the endoscope, such that at least either the fixed reflecting surface or the pivotable reflecting surface is curved. | 2012-02-09 |
| 20120035422 | Endoscope with adjustable viewing angle - An endoscope with adjustable viewing angle includes one of a number of light outlet devices on the distal end of the endoscope, such that the light outlet devices are configured and positioned to conduct illuminating light emerging from different light outlet devices into at least partly different solid angles, several lightwave conductors to conduct illuminating light to the light outlet devices and a light splitting device for controllably switching illuminating light into one or more of the number of lightwave conductors. | 2012-02-09 |
| 20120035423 | SURGICAL ACCESS INSTRUMENT - Embodiments of the invention include instruments and methods for providing surgical access to a surgical site. Some embodiments include a flexible arm that adjustably holds a retractor blade to enable access to the surgical site. | 2012-02-09 |
| 20120035424 | QUICK-ACTION TENSIONING CLIP OF A WOUND RETRACTOR - A quick-action tensioning clip of a wound retractor, with at least one braceable seat for at least one holding arm and/or for a joint ball of a holding arm, is made available which can be operated safely, easily and quickly and which requires only low operating forces and at the same time safely and permanently generates high clamping forces, this being achieved by the fact that, in order to generate the tensioning force, it is equipped with a toggle catch composed of two joint levers which are connected to each other via a connecting joint and which, at their free ends, are articulated via attachment joints on component parts of the quick-action tensioning clip that can be mechanically moved away from or towards one another. | 2012-02-09 |
| 20120035425 | Illuminated Surgical Instrument - An illuminated surgical instrument is disclosed. One embodiment of the illuminated surgical instrument comprises a cannula and an injection-molded light-sleeve adjacent to and encircling at least a portion of the cannula. The surgical instrument can be a vitrectomy probe having a cutting port disposed at a distal end of the cannula. The light-sleeve can terminate near a distal end of the cannula, for example, near the cutting port of the vitrectomy probe. The light-sleeve is optically coupled to a light source. The light-sleeve can be injection-molded during manufacture using the cannula as an insert for the injection molding. The light-sleeve can be oriented for providing illumination in a direction along a longitudinal axis of the instrument. | 2012-02-09 |
| 20120035426 | Extended range physiological monitoring system - A physiological monitoring system includes a sensor subsystem worn by a person including at least one physiological sensor. A dock associated with the sensor subsystem includes a first connector component electrically connected to the physiological sensor. A portable transmitting unit is received by the dock and includes a transmitter and a connector component removeably mateable with the dock connector component to route physiological data to the transmitter. A base station receives and displays physiological data. A portable relay unit includes a receiver for receiving physiological data from the portable transmitting unit, a transmitter for relaying physiological data to the base station, an antenna subsystem for the receiver and transmitter, and a portable power source for the receiver and transmitter. | 2012-02-09 |
| 20120035427 | System and Method of Using Location Technology to Aid Patient Recovery - A system for telemetrically monitoring a patient includes a remote monitoring device associated with the patient. A location services system tracks a location of the remote monitoring device. A patient tracking computer calculates a distance and a duration of patient ambulation from the tracked location. A method of monitoring an ambulatory patient monitors the location of a remote monitoring device and derives ambulatory event data from the monitored location. | 2012-02-09 |
| 20120035428 | MEASUREMENT OF EMOTIONAL RESPONSE TO SENSORY STIMULI - A method of measuring emotional response of at least one subject to a specific sensory stimulus comprises establishing ( | 2012-02-09 |
| 20120035429 | ANIMAL SYMPTOM VISUAL ANALYTICS - A system and method for visually displaying and analyzing public health data for geospatial and/or time variations, including the collection of symptom data coupled with geographic and time data, filtering the symptom data based upon a selected time period and geographic range, and creating a visual result based upon statistical modeling including power transform and/or data normalization. According to at least one embodiment, the system for visually displaying and analyzing includes selecting and performing at least one aberration detection method such as applying CUSUM analysis, quantile measures, and/or bootstrapping analysis, and displaying the result to a user via a visual analytics arrangement. | 2012-02-09 |
| 20120035430 | METHODS AND SYSTEMS FOR DIAGNOSIS AND TREATMENT OF A DEFINED CONDITION, AND METHODS FOR OPERATING SUCH SYSTEMS - Disclosed herein, inter alia, are a method, system and a kit for improving a defined condition in a subject, the method comprising selecting a set of one or more correction zones, being surface zones on the surface of the subject's skin or defined angular zones in the subject's field of view, the one or more correction zones being associated with the condition; and placing the one or more correcting elements in said one or more correction zones to thereby cause improvement in said condition. Also provided herein are methods and systems for providing such correction zones related to a defined condition in a subject or to a defined cause in a subject being associated with a defined condition. | 2012-02-09 |
| 20120035431 | Devices and methods for monitoring physiological information relating to sleep with an implantable device - Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof. | 2012-02-09 |
| 20120035432 | MEDICAL DEVICE AND METHODS OF MONITORING A PATIENT WITH RENAL DYSFUNCTION - Embodiments relate to a method of monitoring physiological parameters of a patient with renal dysfunction. The method includes electrically connecting one or more medical device electrodes with a measurement site of a patient, generating one or more first stimulation signals sufficient to provide input physiological parameters specific to the patient, measuring one or more first bioimpedance values from the generated signals, analyzing at least one of the input physiological parameters within the one or more first bioimpedance values and generating a personalized dialysis program. The systems and methods can further provide essentially real-time data of patient undergoing treatment and control of treatment to a patient. | 2012-02-09 |
| 20120035433 | Examination and imaging of brain cognitive functions - A system for examining biological tissue of a subject includes a wireless optical probe, electronics and a processor. The wireless optical probe includes a light source connected to receive signals from a wireless receiver, and a light detector coupled to provide data to a wireless transmitter constructed to transfer data wirelessly. The wireless optical probe is powered by a battery. The light source is constructed and arranged to introduce optical radiation in the visible to infra-red range into the examined biological tissue of a subject, and the light detector is constructed and arranged to detect radiation that has migrated in the examined biological tissue of the subject. The electronics is constructed and arranged to communicate wirelessly with the optical probe, to store the transferred data, and to create optical data. The processor is constructed and arranged to evaluate the optical data. The system may also provide brain stimulation and evaluate the detected radiation to determine a brain cognitive function of the subject. One embodiment of the system can detect a brain disorder. Another embodiment of the system can detect “deceit.” In addition to the optical module, the system may include other optional modules such as an EEG module, an MEG module, a thermography module, a respiratory module, a skin conductivity module, and a blood pressure module. | 2012-02-09 |
| 20120035434 | Control of a lumen traveling device in a body tube tree - Methods of controlling the operation of a device traveling in a body tube tree, including storing information regarding portions of the body tube tree and performing an action based on sensed parameters, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described. | 2012-02-09 |
| 20120035435 | ELECTROCARDIOGRAM MONITOR - A device is provided for sensing an electrocardiogram signal of a patient. The device includes a substrate and a plurality of electrodes mounted to the substrate. The plurality of electrodes are configured to sense an electrocardiogram signal of a patient when the plurality of electrodes are placed in contact with the patient. The device may include a strap configured to wrap around a portion of the patient wherein the substrate mounts to the strap. The device further may include a respiration sensor mounted to the strap. | 2012-02-09 |
| 20120035436 | HEART MONITOR - A medical device includes a preload determination unit for determining the preload of a ventricle for a cardiac cycle and providing a preload value representing the preload; a contractility determination unit for determining the contractility of the ventricle for the cardiac cycle and providing a contractility value representing the contractility; and an evaluation unit connected to the preload determination unit and the contractility determination unit, with the evaluation unit being configured to evaluate contractility values versus associated preload values. | 2012-02-09 |
| 20120035437 | Navigation of a lumen traveling device toward a target - Methods of controlling the operation of a device traveling in a body tube tree, including, for example, moving the device toward a target location in the body tube tree, and performing an action at the target location. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described. | 2012-02-09 |
| 20120035438 | Path selection by a lumen traveling device in a body tub tree based on previous path - Methods of controlling the operation of a device traveling in a body tube tree, including selecting a direction of travel of the device through the body tube tree based upon whether or not the device has previous travelled in a particular direction, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described. | 2012-02-09 |
| 20120035439 | Map-based navigation of a body tube tree by a lumen traveling device - Method of controlling the operation of a device traveling in a body tube tree, including, determining the location of the device on a map of the body tube tree and planning a path of travel for the device toward a target location. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described. | 2012-02-09 |
| 20120035440 | Parameter-based navigation by a lumen traveling device - Methods of controlling the operation of a device traveling in a body tube tree, including sensing parameters from possible directions of travel and selecting the direction of travel based on the sensed parameters, implemented with a control system located partially or fully on the lumen traveling device. Various actions can be performed by the device for, e.g., medical or therapeutic purposes. Machine-readable media including instructions for performing the methods are also described. | 2012-02-09 |
| 20120035441 | MOUNT UNIT, SENSOR UNIT, MEASUREMENT APPARATUS AND SENSOR FIXATION METHOD - A mount unit | 2012-02-09 |
| 20120035442 | PORTABLE RAMAN DIAGNOSTIC SYSTEM - The present invention further relates to the selection of the specific filter combinations, which can provide sufficient information for multivariate calibration to extract accurate analyte concentrations in complex biological systems. The present invention also describes wavelength interval selection methods that give rise to the miniaturized designs. Finally, this invention presents a plurality of wavelength selection methods and miniaturized spectroscopic apparatus designs and the necessary tools to map from one domain (wavelength selection) to the other (design parameters). Such selection of informative spectral bands has a broad scope in miniaturizing any clinical diagnostic instruments which employ Raman spectroscopy in particular and other spectroscopic techniques in general. | 2012-02-09 |
| 20120035443 | MEDICAL SENSOR FOR REDUCING MOTION ARTIFACTS AND TECHNIQUE FOR USING THE SAME - A sensor for pulse oximetry or other applications utilizing spectrophotometry may be adapted to reduce motion artifacts by fixing the optical distance between an emitter and detector. A flexible sensor is provided with a stiffening member to hold the emitter and detector of the sensor in a relatively fixed position when applied to a patient. Further, an annular or partially annular sensor is adapted to hold an emitter and detector of the sensor in a relatively fixed position when applied to a patient. A clip-style sensor is provided with a spacer that controls the distance between the emitter and detector. | 2012-02-09 |
| 20120035444 | INTRAVITAL SAMPLE DEVICE FOR IN VIVO DRUG SCREENING - The present invention provides sample devices. The present invention also provides in vivo drug screening systems. The present invention further provides a method for in vivo drug screening. | 2012-02-09 |
| 20120035445 | SILICONE BASED MEMBRANES FOR USE IN IMPLANTABLE GLUCOSE SENSORS - Membrane systems incorporating silicone polymers are described for use in implantable analyte sensors. Some layers of the membrane system may comprise a blend of a silicone polymer with a hydrophilic polymer, for example, a triblock poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) polymer. Such polymeric blends provide for both high oxygen solubility and aqueous analyte solubility. | 2012-02-09 |
| 20120035446 | METHOD AND APPARATUS FOR MONITORING DIABETIC PATIENTS - Diabetic patients are provided with blood sugar testers that are used to check the sugar level of the patients at home. The blood sugar data from the testers is automatically transmitted to a data bank that collects the data for each day from a plurality of patients and presents the data to the physician as required. Patients may also be provided with A1c testers that measure and transmit to the data bank A1c data collected monthly. This A1c data is also presented to the physicians so that the physicians can make an appropriate drug dosage level for each patient. | 2012-02-09 |
| 20120035447 | MEDICAL DEVICE WITH A COLLECTION CHANNEL FOR A BODILY FLUID - A medical device for carrying out at least one medical function. The medical device comprises at least one control part, which can be applied to a body surface of a user, and at least one functional element, which can be inserted into a body tissue of the user at at least one insertion site. The functional element can be connected to the control part. The functional element is designed to carry out at least one medical function. The control part has at least one base part with at least one supporting surface, which faces the body surface. The base part has at least one collection channel for collecting bodily fluid emerging from the insertion site. | 2012-02-09 |
| 20120035448 | Analyte Monitoring and Management Device and Method to Analyze the Frequency of User Interaction with the Device - Methods and Devices to monitor the level of at least one analyte are provided. | 2012-02-09 |
| 20120035449 | Apparatus method and for intelligent electronic medical devices - An enhanced electronic medical device is provided that combines some of the enhanced electronic features found in other electronic medical devices with software for executing a stochastic process control and evaluating the digital respiratory and other physiological data collected by the electronic medical device. The programmed stochastic process control is capable of selecting and calculating any one of a number of pulmonary function and other physiological parameters including at least one statistical process control variable to determine a pulmonary or other physiological threshold. Information systems linking doctor's offices and patient's electronic medical devices are further provided to transmit warning data in cases where the pulmonary or other physiological threshold is exceeded. | 2012-02-09 |
| 20120035450 | BLOOD COAGULATION SYSTEM ANALYZER, AND BLOOD COAGULATION SYSTEM ANALYSIS METHOD AND PROGRAM - A blood coagulation system analysis device capable of analyzing a blood coagulation system with high accuracy, and a method and a program for analysis of a blood coagulation system are proposed. | 2012-02-09 |
| 20120035451 | SAFETY TRANSCUTANEOUS ELECTRODE - Transcutaneous safety electrode assemblies are described that can include a conducting electrode having a sharp end to penetration of the skin of a patient, and a shielding member that is deployable by a user so as to shield the sharp end of the electrode after the electrode is removed from the skin. The shielding member can be deployed by retracting the sharp end of the electrode a protective housing, assisted by spring force provided by the electrode wire so as to self-retract into the protective housing. The deployment and disengagement can be via push button action, and the electrode assembly can be self-retaining on the patient's skin while deployed. | 2012-02-09 |
| 20120035452 | METHOD AND APPARATUS FOR DETERMINING AN IN VIVO POSITION OF AN ESOPHAGEAL CATHETER (As Amended) - In a method and an apparatus for determining the position of an esophageal catheter that is inserted into the esophagus of a patient, the catheter having a number of electrodes, muscular activity of the diaphragm is stimulated by applying a stimulus signal that produces a myoelectrical signal in the diaphragm having a well-defined peak at a specific point in time. The myoelectrical signal is detected by respective pairs of electrodes of said catheter, and the electrode pair or pairs that detected the signal having the highest amplitude at the specific point in time is identified. If this electrode pair or these electrode pairs that detected the signal with highest amplitude are not located approximately at the middle of the catheter, an indication is emitted that the position of the catheter should be adjusted. | 2012-02-09 |
| 20120035453 | IMPLANT AND SYSTEM FOR PREDICTING DECOMPENSATION - An implant predicts decompensation of a patient's heart based on an acoustic pressure measurement. The implant includes first and second acoustic transducers, which are matched to each other and which rest in/on the patient's thorax. The first acoustic transducer emits an acoustic signal which has at least one first signal portion having a first frequency. The second acoustic transducer is designed to receive and re-emit the emitted acoustic signal, or to reflect it, such that the first acoustic transducer receives the emitted acoustic signal. A signal processing unit communicates with at least one of the two acoustic transducers and determines an attenuation value as a function of the attenuation of the received acoustic signal versus the originally emitted acoustic signal, and provides a prediction signal as a function of a comparison of the attenuation value to a threshold value, wherein the prediction signal indicates the development of decompensation. | 2012-02-09 |
| 20120035454 | METHOD AND APPARATUS FOR IMAGING OF VESSEL SEGMENTS - An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure. | 2012-02-09 |
| 20120035455 | Initiating a Scan in a Medical Imaging System - A method of initiating a scan in a medical imaging device includes detecting a patient-ready signal from a magnetically and radiographically inert communication device and automatically initiating the scan upon detecting the patient-ready signal. | 2012-02-09 |
| 20120035456 | ARRANGEMENT FOR IMAGING AN OBJECT INCLUDING A VESSEL USING MAGNETIC PARTICLE IMAGING - An arrangement ( | 2012-02-09 |
