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06th week of 2012 patent applcation highlights part 45
Patent application numberTitlePublished
20120035257Histone Deacetylase Inhibitors - Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, such as, for example, a hydroxamic acid group or a carboxylic acid group, can inhibit histone deacetylase. Histone deacetylase can repress gene expression, including expression of genes related to tumor suppression. Accordingly, inhibition of histone deacetylase can provide an alternate route for treating cancer, hematological disorders, e.g., hemoglobinopathies, and genetic related metabolic disorders, e.g., cystic fibrosis and adrenoleukodystrophy.2012-02-09
20120035258METHODS OF USING PRODRUGS OF PREGABALIN - The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.2012-02-09
20120035259Controlled Release of Nitric Oxide And Drugs From Functionalized Macromers And Oligomers - The present invention provides NO and, optionally, drug releasing macromers and oligomers wherein the drug molecule and NO releasing moiety are linked an absorbable macromer or oligomeric chain susceptible to hydrolytic degradation and wherein the macromer or oligomer comprises of repeat units derived from safe and biocompatible molecules such as glycolic acid, lactic acid, caprolactone and p-dioxanone. Furthermore, the present invention relates to controlled release of nitric oxide (NO) and/or drug molecule from a NO and drug releasing macromer or oligomer. Moreover, the present invention also relates to medical devices, medical device coatings and therapeutic formulations comprising of nitric oxide and drug releasing macromers and oligomers of the present invention.2012-02-09
20120035260TELLURIUM-CONTAINING COMPOUNDS FOR AFFECTING FEMALE'S REPRODUCTIVE SYSTEM FOLLOWING CHEMOTHERAPY AND/OR RADIOTHERAPY - Use of tellurium-containing compounds in a method of conception and/or for maintaining and/or augmenting fertility in female following chemotherapy and/or radiotherapy is disclosed. The tellurium-containing compound is utilized in combination with a chemotherapeutic agent and/or radiation, such that the female treated by the chemotherapeutic agent and/or radiation and by the tellurium-containing compound is instructed to refrain from conceptive sex for a pre-determined time period, following the chemotherapy and/or radiotherapy, during which conception is undesired. The tellurium-containing compound is utilized in combination with a chemotherapeutic agent and/or radiation, such that the female treated by the chemotherapeutic agent and/or radiation and by the tellurium-containing compound is instructed to refrain from sex and/or from reproduction for a pre-determined time period, and is then allowed to practice reproduction.2012-02-09
20120035261DEUTERIUM-ENRICHED SAXAGLIPTIN - The present application describes deuterium-enriched saxagliptin, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.2012-02-09
20120035262COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES - In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.2012-02-09
20120035263CONDIMENT - The present invention relates to a condiment comprising an emulsion of an aqueous phase and an oil or fat phase, the emulsion comprising a potato protein protease inhibitor isolate. The invention further relates to a method for preparing a condiment according to any of the preceding claims, comprising preparing an aqueous phase comprising the protein protease inhibitor isolate and thereafter dispersing the oil or fat phase in the aqueous phase or dispersing the aqueous phase in the oil or fat phase.2012-02-09
20120035264Use of methionine sulfoximine to treat acute liver failure and other diseases caused by an inflammatory cytokine response - Methods for treating or preventing an inflammatory response comprising administering an enantiomer or racemic mixture of methionine sulfoximine (MSO). The MSO may be L-methionine S-sulfoximine (LSMSO), L-methionine R-sulfoximine (LRMSO), or racemic mixture of LSMSO and LRMSO. Methods include those for treating liver failure associated with an inflammatory response.2012-02-09
20120035265COMPOSITIONS, METHODS, AND DEVICES FOR THE TREATMENT OF DYSMENORRHEA - A method for a prevention and/or treatment of dysmenorrhea or amelioration of a symptom thereof in a subject, comprising administering to said subject an effective amount of a compound of formula I:2012-02-09
20120035266BIS(THIO-HYDRAZIDE AMIDE) SALTS FOR TREATMENT OF CANCERS - Disclosed are bis(thio-hydrazide amide) disalts and pharmaceutical compositions thereof. Also disclosed are methods of using bis(thio-hydrazide amide) disalts to treat cancer.2012-02-09
20120035267PARACETAMOL FOR PARENTERAL ADMINSTRATION - The invention relates to an aqueous pharmaceutical composition, preferably an infusion solution, for parenteral administration which contains paracetamol and has an electrical conductivity of not more than 200 μS cm2012-02-09
20120035268SPHINGO-GUANIDINES AND THEIR USE AS INHIBITORS OF SPHINGOSINE KINASE - The presently disclosed subject matter provides compounds of the formula: (1) and pharmaceutically acceptable salts thereof, wherein R2012-02-09
20120035269CYCLOPROPENE AMINE COMPOUNDS - Methods of applying cyclopropene amine derivatives and compositions thereof to inhibit ethylene receptors in plants and plant material are disclosed. Methods include applying to the plant an effective ethylene response-inhibiting amount of at least one cyclopropene amine compound or composition thereof. Cyclopropene amine compounds, enantiomers, stereoisomers or salts thereof are also provided.2012-02-09
20120035270PAEDIATRIC SOLUTIONS COMPRISING A BETA-BLOCKER - The present invention relates to aqueous non alcoholic solutions comprising a beta-blocker, a non sugar type sweetener and being substantially free of an aromatic preservative agent. The solutions of the present invention are particularly adapted for a paediatric use.2012-02-09
20120035271Stereoisomers Propofol Therapeutic Compounds - A (−)-stereoisomer of formula (I): [insert formula (I) wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful as an anesthetic.2012-02-09
20120035272Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration - Disclosed is a pharmaceutical composition for treating oxidative stress comprising a therapeutically effective amount of a substantially pure compound of pterostilbene and a physiologically acceptable carrier. Pterostilbene is administered in an amount between about 2.5 mg to about 10 mg per kilogram of subject body weight. Also disclosed is a method for increasing a working memory of a subject, the method comprising administrating an effective amount of a substantially pure compound of pterostilbene, wherein the working memory for a subject increase and the therapeutic effectiveness is about 10 mg of pterostilbene per kilogram of subject body weight.2012-02-09
20120035273PHARMACEUTICAL COMPOSITION COMPRISING GLYCEROL, WHITE SOFT PARAFFIN AND LIQUID PARAFFIN FOR THE TREATMENT OF UREMIC XEROSIS AND/OR PRURITUS - The invention relates to a pharmaceutical composition comprising a combination of glycerol, white soft paraffin and liquid paraffin as active ingredients for topical use to treat uremic xerosis and/or uremic pruritus.2012-02-09
20120035274Composition for Prevention or Treatment of Obesity, Dyslipidemia, Fatty Liver or Insulin Resistance Syndrome Comprising Camphene as Active Ingredients - Disclosed is a composition including camphene as an active ingredient for preventing or treating obesity, dyslipidemia, fatty liver or insulin resistance syndrome. The composition of the present disclosure including camphene as an active ingredient suppresses differentiation of adipocytes, reduces body fat, reduces visceral fat, reduces total cholesterol level, reduces serum triglyceride level and reduces liver tissue triglyceride level, and thus exhibits preventive or therapeutic activity for obesity, hyperlipidemia or fatty liver. Furthermore, the composition of the present disclosure exhibits the effect of improving type 2 diabetes or insulin resistance and related metabolic disease by significantly reducing fasting blood sugar level and blood insulin level. Also, the composition of the present disclosure exhibits the effect of reducing visceral fat by significantly reducing the expression of nuclear transcription factors (C/EBPα and PPARγ2) playing key roles in adipogenesis or their target gene (aP2), the effect of improving chronically activated inflammation in the visceral fat tissue induced by obesity by significantly reducing the expression of cytokines (TNF-α or IL-6) activating inflammation, and the effect of improving suppressed heat generation in the visceral fat tissue induced by obesity by significantly increasing the expression of UCP (UCP1 or UCP3) genes regulating body heat production.2012-02-09
20120035275Emulsion, Method For Producing The Same, And Cosmetic Raw Material Formed From The Same - The present invention has objectives to provide an emulsion suitable as a cosmetic raw material and to easily obtain the aforementioned emulsion of organopolysiloxane exhibiting superior storage stability. The present invention provides an emulsion comprising (A) an organopolysiloxane, (B) a methyl polyglycerol-modified silicone-based surfactant having a specified structure, and (C) an aqueous medium, and provides a method for producing an emulsion characterized by obtaining an emulsion by emulsifying a mixture of (A) a organopolysiloxane and (B) a silicone-based surfactant, which is obtained by synthesizing the silicone-based surfactant of component (B) in the component (A).2012-02-09
20120035276TISSUE REGENERATIVE COMPOSITION, METHOD OF MAKING, AND METHOD OF USE THEREOF - A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.2012-02-09
20120035277LIQUID-FILLED CHEWABLE SUPPLEMENT - A liquid-filled chewable composition for the oral delivery of nutritional supplements and/or pharmaceuticals is provided. The chewable composition includes a delivery vehicle and an active ingredient incorporated therein. The delivery vehicle may include an organic or non-organic gummy candy including a binding agent, sweetener, flavoring, and/or coloring. The active ingredient may include a predetermined amount of any combination of pharmaceuticals, nutraceuticals, vitamins, minerals, antioxidants, soluble and insoluble fiber, herbs, plants, probiotics, prebiotics, antioxidants, amino acids, fatty acids, digestive enzymes, dietary supplements, or any other health promoting ingredient. The delivery vehicle may also include a predetermined amount of at least one nutritional supplement and/or pharmaceutical compound.2012-02-09
20120035278PREPARING AMINOTRIAZINE ALKOXYLATES - The present invention relates to a process for preparing aminotriazine alkoxylates, which comprises at least one aminotriazine alkoxylate (a) being admixed with at least one aminotriazine (b) and reacted with at least one alkylene oxide (c), wherein the aminotriazine alkoxylate (a) is obtainable by reacting at least one aminotriazine (d) with at least one alkylene oxide (e) and/or at least one alkylene carbonate (g), and optionally at least one aminotriazine alkoxylate (f).2012-02-09
20120035279PROTOCOL FOR SCREENING TRAVELERS - Methods for screening a traveler for an evaluation of the traveler's physical condition or health status by obtaining at least one specimen from the traveler and subjecting the specimen to at least one test that is diagnostic for at least one parameter of the physical condition or health status of the traveler prior to or while the traveler undertakes a journey. Thereafter, the results of the diagnostic test are reported prior to or contemporaneous with the arrival of the traveler at the traveler's destination.2012-02-09
20120035280ANION EXCHANGE MEMBRANE AND METHOD FOR PRODUCING SAME - There is provided an anion exchange membrane comprising, as a main element, a block copolymer having a vinyl alcohol polymer block and a cationic-group containing polymer block as components and which is subjected to a crosslinking treatment. An anion exchange membrane is produced by heating a film obtained from a solution of the block copolymer at a temperature of 100° C. or more, crosslinking the film with a dialdehyde compound in water, an alcohol or a mixture of these under an acidic condition and then washing the film with water. Thus, there can be provided an anion exchange membrane in which organic fouling can be prevented and which exhibiting excellent basic properties such as a membrane resistance and an ionic transport number and excellent membrane strength.2012-02-09
20120035281PHOSPHORUS-ADSORBING MATERIAL AND PHOSPHORUS RECOVERY SYSTEM - A phosphorus-adsorbing material is produced to include a polymer-based material modified with at least either of a primary and a secondary amine and a metal supported on the polymer-based material, and a phosphorus recovery system is structured by using the phosphorus-adsorbing material.2012-02-09
20120035282PROCESS FOR THE CONTINUOUS CYCLE RECYCLING OF MATERIALS CONTAINED IN PRODUCTS COUPLED TO OTHER MATERIALS BY DISINTEGRATION THROUGH WATER JETS AT HIGH/ULTRAHIGH PRESSURE AND PRODUCTS OBTAINED IN THIS WAY - A process and a plant, even mobile, for the continuous cycle recycling of materials (2012-02-09
20120035283Expandable Functional TFE Copolymer Fine Powder, the Expanded Functional Products Obtained Therefrom and Reaction of the Expanded Products - A functional TFE copolymer fine powder is described, wherein the TFE copolymer is a polymer of TFE and at least one functional comonomer, and wherein the TFE copolymer has functional groups that are pendant to the polymer chain. The functional TFE copolymer fine powder resin is paste extrudable and expandable. Methods for making the functional TFE copolymer are also described. The expanded functional TFE copolymer material may be post-reacted after expansion.2012-02-09
20120035284BIOCIDAL PARTICLES OF METHYLATED POLYSTYRENE - Methylated polystyrene having pendant N-halamine and N-halamine precursor groups. Biocidal particles have been prepared by reacting highly crosslinked methylated polystyrene beads as starting materials with various N-halamine precursor compounds. The resulting polymer beads are halogenated with chlorine or bromine. The porous beads will be useful in disinfection applications as well as for sanitization and controlling noxious odor when mixed with absorbent materials in items such as disposable diapers, infant swimwear, incontinence pads, bandages, sanitary napkins, pantiliners, mattress covers, shoe inserts, sponges, animal litter, carpets, and fabrics.2012-02-09
20120035285POLYOLEFIN POROUS FILM, METHOD FOR PRODUCING THE SAME AND APPARATUS FOR PRODUCING THE SAME - The present invention relates to a method for producing a polyolefin porous film, the method including the steps of: (a) melt-kneading a solution containing a polyolefin having a weight average molecular weight of 500,000 or more and a solvent to obtain a kneaded product; (b) extruding and cooling the kneaded product to obtain a gel-like molded product; (c) drawing the gel-like molded product to obtain a drawn sheet; (d) removing the solvent from the drawn sheet, followed by drying to obtain a film in which fine pores are formed; (e) conducting heat treatment, while fixing the film in both directions of a MD and a TD thereof and drawing the film at a draw ratio of exceeding 0% to less than 0.1% in at least one direction of the MD and the TD thereof; and (f) conducting heat treatment while decreasing a width of the film in at least one direction of the MD and the TD of the film.2012-02-09
20120035286POLYMER MIXTURES COMPRISING HALOGEN - The invention relates to polymer mixtures comprising at least one polymer, at least one organic halogenated compound such as halogenated flame retardants and also at least one further compound to thermally stabilize the organic halogenated compound, this further compound having a saponification number of 80 to 300 mg KOH/g and an OH number of 200 to 800 mg KOH/g.2012-02-09
20120035287HIGH HEAT RESISTANT POLYMER COMPOSITIONS HAVING POLY(LACTIC ACID) - High heat resistant polymer compositions having poly(lactic acid) and methods of making the high heat resistant polymer compositions are provided. In a general embodiment, the present disclosure provides a polymer composition including a poly(lactic acid), an aliphatic polyester, and an organically coated calcium carbonate.2012-02-09
20120035288FORMING COPOLYMER FROM BICONTINUOUS MICROEMULSION COMPRISING MONOMERS OF DIFFERENT HYDROPHILICITY - A copolymer defines interconnected pores and comprises polymerized monomers. The monomers comprise a first monomer more hydrophilic than 2-hydroxyethyl methacrylate (HEMA), and a second monomer as hydrophilic as, or less hydrophilic than, HEMA. In a method of forming a polymer, a bicontinuous microemulsion comprising water, a surfactant, and a combination of monomers copolymerizable for forming a porous copolymer is provided. The combination of monomers comprises the first and second monomers. The monomers in the bicontinuous microemulsion are polymerized to form the porous copolymer. The first monomer may comprise N-vinylpyrrolidone (NVP) or methacrylic acid (MAA). The second monomer may comprise HEMA or methyl methacrylate (MMA).2012-02-09
20120035289CATALYST COMPOSITION FOR PRODUCTION OF RIGID POLYURETHANE FOAM AND ISOCYANURATE-MODIFIED RIGID POLYURETHANE FOAM AND RAW-MATERIAL COMPOSITION CONTAINING THE SAME - An object of the present invention is to provide a catalyst for producing a rigid polyurethane foam and an isocyanurate-modified rigid polyurethane foam excellent in storage stability in the case that water is contained as a blowing agent, and a raw material-blended composition using the same.2012-02-09
20120035290PROPYLENE POLYMER RESIN COMPOSITION - A propylene polymer resin composition comprising 50-99 wt. % of a propylene polymer resin and 1-50 wt. % of an ethylene polymer resin, wherein said ethylene polymer resin has the following characteristics (A) through (E): (A) a density (d), as measured by a density gradient tube method according to JIS K6760, of 940-960 kg/m2012-02-09
20120035291METHODS OF MERCAPTANIZING OLEFINIC HYDROCARBONS AND COMPOSITIONS PRODUCED THEREFROM - The present invention discloses processes for forming polythiol compositions from olefinic hydrocarbons such as cyclooctadiene, cyclododecatriene, and trivinylcyclohexane. The polythiol compositions produced from these processes, including the sulfur-containing compounds of these compositions, also are described.2012-02-09
20120035292LIQUID PHOTOINITIATOR BLEND - The present invention relates to a homogenous liquid blend comprising a photoinitiator and an alkoxylate surfactant for incorporation into aqueous based and solvent based radiation curable systems. In particular the invention relates to a homogenous liquid blend which is liquid at room temperature comprising at least 30% by weight with regard to the whole blend of a solid photoinitiator of the radical type and 1-70% by weight of at least one alkoxylated liquid surface active agent and optionally an organic diluent.2012-02-09
20120035293ON-DEMAND PHOTOINITIATED POLYMERIZATION - Compositions and methods for adjustable lenses are provided. In some embodiments, the lenses contain a lens matrix material, a masking compound, and a prepolymer. The lens matrix material provides structure to the lens. The masking compound is capable of blocking polymerization or crosslinking of the prepolymer, until photoisomerization of the compound is triggered, and the compound is converted from a first isomer to a second isomer having a different absorption profile. The prepolymer is a composition that can undergo a polymerization or crosslinking reaction upon photoinitiation to alter one or more of the properties of the lenses.2012-02-09
20120035294Process for Preparing Super Absorbent Polymers - The present invention relates to a process for preparing super absorbent polymers, and more specifically to a process for preparing super absorbent polymers comprising the steps of: forming a monomer composition comprising water-soluble, ethylenic unsaturated monomers and non-reactive fine particles having a diameter of 20 nm to 1 mm; and subjecting the monomer composition to a thermal polymerization or a UV-induced polymerization.2012-02-09
20120035295METHOD FOR REMOVING VINYL MONOMERS FROM A GAS STREAM - A method for removing vinyl monomers from a gas stream comprises steps of: irradiating a photoactive-inorganic medium by a light emitting unit to activate the photoactive-inorganic medium; and pumping a gas stream including vinyl monomers to contact with the activated photoactive-inorganic medium to make the vinyl monomers in the gas stream to polymerize on the photoactive-inorganic medium to jointly form a polymeric nano-composite.2012-02-09
20120035296BONE CEMENT COMPOSITION, BONE CEMENT COMPOSITION KIT AND FORMING METHOD OF BONE CEMENT HARDENED MATERIAL - The invention has as its objects the provision of a bone cement composition, a bone cement composition kit for obtaining the bone cement composition, and a production method of a bone cement hardened material, which are short in doughing time that is a time required to become a state in which a good handling operation can be conducted, and have consequently capable of achieving a high working efficiency by shortening the time required before the handling operation is started.2012-02-09
20120035297REMEDIATION OF AGGLOMERATED FLOW IMPROVERS - The present embodiment can teach a method of feeding to a materials processor a mixture containing an agglomerated drag reducer. The mixture is then homogenized to produce a remediated drag reducer. The maximum particle size diameter of the agglomerated drag reducing polymer is at least 5% larger than the maximum particle diameter of the remediated drag reducer.2012-02-09
20120035298POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES - Provided are polyhydroxy-diamine compounds of the formula I: or salt thereof, wherein R2012-02-09
20120035299EPOXY RESIN COMPOSITION FOR FIBER-REINFORCED COMPOSITE MATERIAL, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL - Disclosed is a fiber-reinforced composite material that is high in heat resistance and strength while being low in the content of volatile matter that volatilizes during curing. Also disclosed are an epoxy resin composition for production thereof, and a prepreg produced from the epoxy resin composition. Specifically the invention provides an epoxy resin composition comprising: [A] an epoxy resin comprising two or more ring structures each consisting of four or more members, and at least one amine type or ether type glycidyl group directly connected to the ring structures, [B] a tri—or more—functional epoxy resin, and [C] a curing agent, and also provides a prepreg produced by impregnating reinforcing fiber with the epoxy resin composition and a fiber-reinforced composite material produced by curing the prepreg.2012-02-09
20120035300Semi-Continuous Method For Producing Copolymers - The present invention relates to a process for the preparation of a copolymer in semicontinuous operation in a polymerization apparatus, comprising a polymerization reactor connected to a metering device, in each case acid monomer being initially taken in the metering device and polyether macromonomer and water in the polymerization reactor, acid monomer being metered from the metering device via an acid monomer metering line into the polymerization reactor, free radical polymerization initiator being passed into the polymerization reactor before and/or during the metering of the acid monomer into the polymerization reactor so that an aqueous medium in which acid monomer and polyether macromonomer are reacted with formation of the copolymer by free radical polymerization forms in the polymerization reactor, a portion of the copolymer-containing aqueous medium being passed continuously during the free radical polymerization from the polymerization reactor via a reaction mixture line which is connected via a mixing device to the acid monomer metering line, the discharged copolymer-containing aqueous medium being mixed with the acid monomer in the mixing device during the metering of the acid monomer and being recycled to the polymerization reactor after the mixing via the acid monomer metering line.2012-02-09
20120035301Method For The Production Of Copolymers - The invention relates to a process for the preparation of a copolymer in semicontinuous operation in a polymerization apparatus, comprising a polymerization reactor connected to a metering device, in each case acid monomer being initially taken in the metering device and polyether macromonomer and water in the polymerization reactor, acid monomer being metered from the metering device into the polymerization reactor, free radical polymerization initiator being passed into the polymerization reactor before and/or during the metering of the acid monomer into the polymerization reactor so that an aqueous medium in which acid monomer and polyether macromonomer are reacted with formation of the copolymer by free radical polymerization forms in the polymerization reactor, the free radical polymerization initiator used being an H2012-02-09
20120035302PROCESS FOR THE PRODUCTION OF A BITUMINOUS COMPOSITION - A process for the production of a bituminous composition, includes (i) producing a mix of aggregates with a maximum diameter less than or equal to 30 mm and of an amount less than or equal to 0.8 g per square metre of specific surface developed by the aggregates of at least one cationic polymer in the liquid form having a density of cationic charges greater than or equal to 0.5 meq/g and an intrinsic viscosity of from 0.01 to 0.8 dl/g; and (ii) putting the mix obtained in stage (i) into contact with at least one bituminous binder. A bituminous composition includes at least one specific cationic polymer and the use of at least one specific cationic polymer in the surface treatment of aggregates intended for the preparation of a bituminous composition are the other two subject-matters of the present invention.2012-02-09
20120035303NON-BLOOMING FLAME RETARDANT THERMOPLASTIC COMPOSITION - This invention relates to a flame retardant thermoplastic composition comprising a thermoplastic polymer composition; a flame retardant containing a phosphorus containing anion; a borate; and an acid scavenger.2012-02-09
20120035304METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN - A method for inhibiting the crystal growth rate of an amide compound present in a molten polyolefin-based resin and a method for producing a polyolefin-based resin molded article are provided.2012-02-09
20120035305Polymers with Low Gel Content and Enhanced Gas-Fading - A polymer stabilizing composition comprising a sterically hindered phenol and a phosphite that provides low gel content and enhanced resistance to gas-fading. The stabilizer composition is particular useful for stabilizing polyethylene homopolymers and copolymers, such as linear low density polyethylenes produced from metallocene catalyst. The sterically hindered phenol is, for example, selected from the group consisting of 1,3,5-tris-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)isocyanurate, 1,3,5-tris-(3,5-dicyclohexyl-4-hydroxybenzyl)isocyanurate, 1,3,5-tris-(3,5-di-tert-butyl-4-hydroxybenzyl)isocyanurate, 1,3,5-tris(4-t-butyl-3-hydroxy-2,6-dimethylbenzyl)-1,3,5-Triazine-2,4,6-(1H,3H,5H)-trione, and 1,3,5-tris-(3,5-di-tert-butyl-4-hydroxybenzyl)-2,4,6-trimethylbenzene.2012-02-09
20120035306ANIONIC FUNCTIONAL PROMOTER AND CHARGE CONTROL AGENT WITH IMPROVED WET TO DRY TENSILE STRENGTH RATIO - The invention relates to a composition comprising (a) a functional promoter comprising a water-soluble anionic polymer having a molecular weight of at least about 50,000 daltons and a molecular weight charge index value of at least about 10,000; (b) a cationic surfactant component; such that when the composition treats a fibrous substrate, in conjunction with a cationic strength agent, the treated fibrous substrate exhibits (i) a ratio of wet tensile strength to dry tensile strength ranging from about 1:5 to about 1:2 and (ii) an increase in a ratio of wet tensile strength to dry tensile strength of at least about 10%, as compared to when the fibrous substrate is treated with the functional promoter and without a surfactant. The invention also relates to a paper product made with such a system, and method for imparting wet strength to a paper product with the functional promoter.2012-02-09
20120035307PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES - The present invention generally relates to a process for preparing stabilized polymeric systems with excellent light, thermal and oxidation stability using a redox formulation containing an oxidizing agent, a reducing agent, and/or nano-additives, and the polymer articles made therefrom.2012-02-09
20120035308METHODS OF MAKING 6-HYDROXYHEXANOPHENONE AND 5-BENZOYLPENTANOIC ACID AND MONO OR DIESTERS THEREOF - Mono- or diester plasticizers of the formula:2012-02-09
20120035309METHOD TO DISPERSE NANOPARTICLES INTO ELASTOMER AND ARTICLES PRODUCED THEREFROM - Methods of making elastomeric nanocomposites with improved nanoparticle dispersion in the elastomer are described. The method includes the use of liquid form additives such as oils, plasticizers and/or solvents as dispersing agents to disperse nanoparticles into elastomers. Also described are articles such as downhole elements including the elastomeric nanocomposites made by the methods described herein.2012-02-09
20120035310COATING COMPOSITIONS CONTAINING LOW VOC COMPOUNDS - Coating compositions containing coalescents and a latex polymer, wherein the coalescent has a volatile organic content of less than about 50% and is dispersible in the coating composition.2012-02-09
20120035311COLORED BUBBLES - A colored bubble composition for producing colored bubbles having water, at least one humectant, at least one water soluble polymer, and at least one colorant. The colored bubble composition may be obtained by mixing water, at least one humectant, and at least one water soluble polymer to form a mixture, wherein the mixture does not comprise a colorant. Subsequently, at least one colorant is added to the mixture. In particular, a mixture of water, at least one humectant, and at least one water soluble polymer may be heated to a temperature in the range of about 40 to 60° C. and subsequently, cooled to about 20 to 30° C. The at least one colorant is then added to the cooled mixture.2012-02-09
20120035312SURFACE-TREATED CALCIUM CARBONATE AND PASTE RESIN COMPOSITION CONTAINING SAME - The invention provides a surface-treated calcium carbonate that when incorporated into a paste resin, can impart low viscosity and high thixotropy and offers excellent storage stability, and paste resin compositions containing the same. The surface-treated calcium carbonate is a calcium carbonate surface-treated with a surface treatment agent containing a sodium salt or potassium salt of a fatty acid, wherein the total content of a sodium salt and a potassium salt of lauric acid, a sodium salt and a potassium salt of palmitic acid and a sodium salt and a potassium salt of stearic acid in the surface treatment agent is 80% by weight or more, the content of the sodium salt and potassium salt of lauric acid is within the range of 30% to 60% by weight, the content of a sodium salt and a potassium salt of an unsaturated fatty acid in the surface treatment agent is 5% by weight or less, and the BET specific surface area is 10 m2012-02-09
20120035313METHOD OF IMPROVING THE BUBBLE STABILITY OF A BLOWN FILM OF A THERMOPLASTIC RESIN - A method of modifying the rheology of a thermoplastic resin that includes the steps of providing a thermoplastic resin and blending interpolymer resin particles with the thermoplastic resin. The interpolymer resin contains a styrenic polymer intercalated within a polyolefin, such that the thermoplastic resin is present as a continuous phase and the interpolymer resin is present as a dispersed phase. The method provides a rheology modified thermoplastic resin with improved physical characteristics.2012-02-09
20120035314Use of Protective Colloid-Stabilized Polymerizates as Low-Profile Additive (LPA) - The invention relates to the use of protective colloid-stabilized polymerizates as low profile additive (LPA), characterized in that the protective colloids carry one or more functional group selected from the group comprising carboxyl, sulfate, sulfonate, phosphate, phosphonate, hydroxyl and nitrogen-functional groups, having the stipulation that the mass fraction of the hydroxyl groups equals ≦10 wt % based on the total mass of a protective colloid.2012-02-09
20120035315METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES - The present invention generally relates to a process for preparing stabilized polymeric systems with excellent light, thermal and oxidation stability using an active, peroxide containing polymer oxidizing agents, amine-containing reducing agents, and/or nano-additives, and the polymer articles made therefrom.2012-02-09
20120035316MACROMONOMERS AND GRAFT COPOLYMERS PREPARED BY EMULSION POLYMERIZATION WITH A COBALT CHELATE CHAIN TRANSFER AGENT - Process for preparing a macromonomer using free radical-initiated aqueous emulsion polymerisation in a polymerisation reactor of at least one olefinically unsaturated monomer, which process employs a hydrophobic Co chelate complex as a CTA, a stabilising substance(s) for the emulsion polymerisation process and a monomer feed stage MF;2012-02-09
20120035317Urea-Terminated Polyurethane Dispersants - The present invention relates to urea-terminated polyurethanes dispersants based on diols and polyether diols, aqueous dispersions of such polyurethanes, the manufacture of the urea terminated polyurethane dispersions and inks containing pigments and/or disperse dyes dispersed with these urea terminated polyurethane dispersants. The urea termination can have nonionic hydrophilic substituents.2012-02-09
20120035318POLYURETHANE DISPERSION, METHOD OF PRODUCING THE SAME, COATED ARTICLES, AND METHOD FOR COATING ARTICLES - The instant invention is a polyurethane dispersion, method of producing the same, coated articles, and method for coating articles. The polyurethane dispersion according to the present inventions includes (a) one or more polyurethane units derived from one or more prepolymers wherein the one or more prepolymers comprise the reaction product of a mixture dissolved in dipropylene glycol dimethyl ether in the presence of one or more first surfactants with one or more isocyanates, wherein the mixture comprises one or more natural oil based polyols, and one or more adipate polyols, and optionally one or more short diols; and (b) water.2012-02-09
20120035319BORATE AND POLYMER COMPOSITIONS FOR THE REPAIR AND MAINTENANCE OF RAILROAD TIES - A remedial railroad tie repair treatment capable of extending the useful life of a railroad tie. The remedial repair treatment comprises a mixture of a borate solution and a chemical tie plugging compound combined that, when applied to a wooden area of interest, will delay the decay thereof and facilitate penetration of the borate through the wood fibers. The remedial repair treatment may alternatively comprise sequential application of the borate solution and the plugging compound to the wooden area of interest.2012-02-09
20120035320POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES - The present invention provides nucleic acid delivery polyplex complexes and anionic open polyplexes comprising a nucleic acid molecule reversibly bound to one or more of nucleic acid delivery polyplex complexes.2012-02-09
20120035321COMPOUNDS AND MEDICAL DEVICES ACTIVATED WITH SOLVOPHOBIC LINKERS - The present disclosure relates to compounds and medical devices activated with a solvophobic material functionalized with a first reactive member and methods of making such compounds and devices.2012-02-09
20120035322POLYNUCLEIC ACID-ATTACHED PARTICLES AND THEIR USE IN GENOMIC ANALYSIS - Disclosed are methods for preparing particle-linked polynucleotides, and using the particle linked polynucleotides in genomic analysis. The particles as disclosed are characterized as having a size variance of less than 2%.2012-02-09
20120035323POLYOLEFIN/POLYLACTIC ACID BLENDS - The invention relates to blends of polyolefins and a biodegradable polymer, such as polylactic acid (PLA) and polyhydroxy butyrate, which are compatabilized by a functionalized olefin (meth)acrylic copolymer. Since PLA and polyolefins are not miscible, the use of the compatibilzer improves the compatibility, thereby improving the processability, and particularly the melt strength and melt elasticity. Useful compatibilizers include Lotader® and Lotryl® copolymers from Arkema, Inc. The blend composition may optionally contain one or more acrylic copolymers as impact modifiers or process aids.2012-02-09
20120035324Process for Preparing a Reinforced and Reactive Thermoplastic Composition, and This Composition - The invention relates to a process for preparing a reinforced and reactive thermoplastic composition having a continuous phase which is based on at least one thermoplastic polymer and dispersed in which is a discontinuous phase based on at least one reactive reinforcing agent that may be immiscible with said at least one thermoplastic polymer, and also to a composition obtained by this process.2012-02-09
20120035325Thermoplastic Elastomeric Compositions - A dynamically vulcanized alloy contains at least one isobutylene-containing elastomer and at least one thermoplastic resin, wherein the elastomer is present as a dispersed phase of small particles in a continuous phase of the thermoplastic resin. The elastomer in the alloy is cured by means of a cure system comprising an increased amount of curative and preferably with no cure accelerators present in the cure system. The elastomer obtains at least seventy five percent cure in not more than 15 minutes at temperatures 220° C. or greater.2012-02-09
20120035326Flex Life of Tetrafluoroethylene/Perfluoro(Alkyl Vinyl Ether) Copolymer (PFA) - A process is provided for improving the MIT flex life of tetrafluoroethylene/perfluoro(alkyl vinyl ether) copolymer, said perfluoroalkyl containing from 1 to 5 carbon atoms, comprising incorporating melt flowable polytetrafluoroethylene into said copolymer and thereafter heat treating the resultant composition at a temperature of at least 280° C., the amount of said polytetrafluoroethylene and said heat treatment being effective to increase the flex life of said composition by at least 2× the flex life of both said copolymer and said composition prior to said heat treatment and to thermally transform the composition in the solid state, which is epitaxial co-crystallization of the polymer components of the composition.2012-02-09
20120035327Polyolefin Masterbatch and Composition Suitable for Injection Molding - A masterbatch composition comprising:2012-02-09
20120035328METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES - Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.2012-02-09
20120035329METHOD FOR PRODUCING STABILIZED FLUOROPOLYMER - The present invention is aimed to provide a highly-productive method for producing a stabilized fluoropolymer. The present invention relates to a method for producing a stabilized fluoropolymer, comprising the step of bringing a fluoropolymer to be treated into contact with a fluorinating agent to produce a stabilized fluoropolymer, while maintaining the concentration of hydrogen fluoride present in a reaction vessel at not higher than 1.0% by volume.2012-02-09
20120035330MOLECULE-BASED MAGNETIC POLYMERS AND METHODS - Molecule-based magnetic polymers with reasonably high Curie temperature and methods of preparing are provided. In particular, magnetic polymers having repeating units of an organometallic monomer covalently bonded to a monomer having a plurality of unpaired electrons are disclosed. Intrinsically homogeneous magnetic fluids (liquid magnets) and methods of preparing are also provided.2012-02-09
20120035331POLYALKYLTHIOPHENE BLOCK COPOLYMER AND A METHOD OF PREPARING THE SAME THROUGH A RING-OPENING METATHESIS POLYMERIZATION REACTION - A polyalkylthiophene block copolymer, a conductive composition including the same, a polymer-catalyst complex in which a polyalkylthiophene and a transition metal catalyst are connected, and a method of preparing a conductive block copolymer from the polymer-catalyst complex through a ring-opening metathesis reaction are provided.2012-02-09
20120035332Extraction of Metals from Solid Mixtures Using Dendritic Macromolecules - Methods and facilities are provided for extracting a metal, such as an actinide from a solid, such as an ore. A novel class of dendritic macromolecules is provided for use in such extraction having a core, a hyperbranched structure, and a plurality of units satisfying the formula —NR2012-02-09
20120035333CARBOXYLIC POLYBENZIMIDAZOLE - A carboxylic polybenzimidazole includes at least one of the following functional group of formula (I):2012-02-09
20120035334METHOD FOR PREPARING CARBOXYLIC POLYBENZIMIDAZOLE - A method for preparing a carboxylic polybenzimidazole includes reacting a polybenzimidazole polymer with a cyclic acid anhydride to form the carboxylic polybenzimidazole.2012-02-09
20120035335APPARATUS AND METHOD OF REACTING POLYMERS PASSING THROUGH METAL ION CHELATED RESIN MATRIX TO PRODUCE INJECTABLE MEDICAL DEVICES - The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly configured to maintain and selective dispense a first precursor and a second precursor, a mixing assembly configured to mix the first and second precursors, and at least one catalyzing element including a transition metal ion to aid in the polymerization of the first and second precursors. The process includes dispensing a volume of the first precursor and a volume of the second precursor into a mixing assembly and mixing the first and second precursors. The first and second precursors each possess a core and at least one functional group known to have click reactivity with each other. The mixed precursors are contacted with a transition metal catalyst to produce a flowable composition for use as a medical device.2012-02-09
20120035336NOVEL MULTIFUNCTIONAL INITIATORS FOR ANIONIC POLYMERIZATION AND POLYMERS THEREOF - The embodiments of the invention relate to a multifunctional lithiated amine-containing compound comprising at least two molecules of lithiated amine in a molecule of the compound. In one embodiment, the compound has a formula2012-02-09
20120035337NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS - The present invention relates to novel materials particularly useful for ophthalmic applications and methods for making and using the same. More particularly, the present invention relates to relatively soft, optically transparent, foldable, high refractive index Materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and using the same.2012-02-09
20120035338CATALYST COMPONENT USED FOR OLEFIN POLYMERIZATION, PROCESS FOR PREPARING THE SAME, AND CATALYST CONTAINING THE SAME - A process for preparing a solid particle-type catalyst component used for olefin polymerization which contains magnesium, titanium, a halogen and an electron donor as essential ingredients, a catalyst component obtained by said process, and a catalyst containing the catalyst component are disclosed.2012-02-09
20120035339ETHYLENE COPOLYMER - The invention is directed to a slurry phase polymerisation process for the preparation of ethylene-α-olefin copolymers by polymerising ethylene in the presence of a chromium containing catalyst and a diluent. The polymerisation takes place in the presence of·a chromium-containing catalyst, ·an aliphatic or alicyclic boron compound having at least one boron to carbon linkage and·an aliphatic or alicyclic group MA or group IMA element based compound having at least one metal or metalloid to carbon linkage wherein the chromium containing catalyst is not reduced by carbon monoxide after the activation in a non-reducting atmosphere and wherein the metal or metalloid is present in an amount higher than 1 ppm relative to the amount of diluent.2012-02-09
20120035340AMINATED HEMICELLULOSE MOLECULE AND METHOD FOR PRODUCTION THEREOF - The present invention relates to a method for reductive amination of a water soluble carbohydrate. An aminated water soluble carbohydrate is a prerequisite in processes for further modification of cellulose. The synthesis of this molecule comprises, providing a water soluble carbohydrate, an amine and a reducing agent, which are reacted under acidic conditions, isolated to give an aminated water soluble carbohydrate with a yield larger than 60%. The invention also relates to an aminated hemicellulose molecule with a molecular weight of at least 1 kDa, especially xyloglucan.2012-02-09
20120035341PROCEDE DE POLYMERISATION PAR VOIE CATALYTIQUE DE 1,4-DIOXANES-2,5-DIONES ET LES POLYMERES CORRESPONDANTS - A method for polymerizing 1,4-dioxane-2,5-diones in the presence of a generally protic initiator and at least one catalyst including at least one metal-free organic compound. The latter is a non-metal organic catalyst most often selected from among pyridines of which DMAP is a derivative, sulfonic acids, polycyclic tertiary amines, phosphazenes, thioureas, thioureas/amines, and guanidines. The invention also relates to polymers obtained by the method.2012-02-09
20120035342Method for Producing Polyester Particles at High Throughput in a Line - The invention relates to a method and to a device for producing a thermoplastic polyester, having the following steps: a) producing polyester pre-polymer particles; b) crystallizing the polyester pre-polymer particles for producing partially crystalline polyester pre-polymer particles; c) heating the partially crystalline polyester pre-polymer particles to a suitable reaction temperature for producing heated polyester pre-polymer particles; d) reacting the heated polyester pre-polymer particles for producing polyester polymer particles having an intrinsic viscosity between 0.70 and 0.95 dl/g. The reaction in step d) takes place in at least one reactor through which the particles flow by means of gravity. The dwell time in the reactor equals between 6 and 30 hours. The particles are supplied at least to step d) at a mass flow of between 40 and 100 t/h. The present invention is characterized in that a settling rate of the particles in the reactor equals between 2 and 6 m/h.2012-02-09
20120035343Method for Functionalization of Nanoscale Fibers and Nanoscale Fiber Films - A method is provided for functionalizing nanoscale fibers including reacting a plurality of nanoscale fibers with at least one epoxide monomer to chemically bond the at least one epoxide monomer to surfaces of the nanoscale fibers to form functionalized nanoscale fibers. Functionalized nanoscale fibers and nanoscale fiber films are also provided.2012-02-09
20120035344NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE - The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein comprising contacting the oxidized carbohydrate moiety with an activated water soluble polymer under conditions that allow conjugation. More specifically, the present invention relates to the aforementioned materials and methods wherein the water soluble polymer contains an active aminooxy group and wherein an oxime or hydrazone linkage is formed between the oxidized carbohydrate moiety and the active aminooxy group on the water soluble polymer, and wherein the conjugation is carried out in the presence of a nucleophilic catalyst.2012-02-09
20120035345PROCESS FOR PREPARING GLYCOPEPTIDES HAVING ASPARAGINE-LINKED OLIGOSACCHARIDES, AND THE GLYCOPEPTIDES - Glycopeptide having at least one asparagine-linked oligosaccharide at a desired position of the peptide chain obtained by: 2012-02-09
20120035346LUMINESCENT COMPOUNDS - Dyes and photoluminescent compounds based on polymethine dyes that contain at least one alkyl-phosphonate or substituted alkyl-phosphonate group, including the synthetic precursors, methods of synthesis, and applications thereof. Certain embodiments include heterocyclic ring systems and polymethine linkage are selected such that the resulting polymethine dye is a cyanine dye, a merocyanine dye, or a styryl dye.2012-02-09
20120035347INTERFERON-ALFA SENSITIVITY BIOMARKERS - The present invention provides biomarkers of sensitivity to interferon alfa (IFN-α). These IFN-α sensitivity biomarkers are useful, inter alia, to identify patients who are most likely to benefit from treatment with pharmaceutical compositions of IFN-α, in methods of treating patients having a disease susceptible to treatment with interferon alfa, and in methods for selecting the most appropriate therapy for such patients.2012-02-09
20120035348SELECTIVE EXTRACTION OF PROTEINS FROM FRESHWATER ALGAE - Methods for selective extraction and fractionation of algal proteins from an algal biomass or algal culture are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which allow for efficient separation of algal proteins. These proteins can be used as renewable sources of proteins for animal feedstocks and human food. Further, lipids remaining in the algal biomass after extraction of proteins can be used to generate renewable fuels.2012-02-09
20120035349SELECTIVE EXTRACTION OF PROTEINS FROM SALTWATER ALGAE - Methods for selective extraction and fractionation of algal proteins from an algal biomass or algal culture are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which allow for efficient separation of algal proteins. These proteins can be used as renewable sources of proteins for animal feedstocks and human food. Further, lipids remaining in the algal biomass after extraction of proteins can be used to generate renewable fuels.2012-02-09
20120035350POLYNUCLEOTIDE ENCODING A NOVEL HUMAN P2X7 SPLICE VARIANT, HBMYP2X7V - The present invention provides novel polynucleotides encoding HBMYP2X7v polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HBMYP2X7v polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.2012-02-09
20120035351Volatile Imidazoles and Group 2 Imidazole Based Metal Precursors - Sterically hindered imidazole ligands are described, along with their synthesis, which are capable of coordinating to Group 2 metals, such as: calcium, magnesium, strontium, in an eta-5 coordination mode which permits the formation of monomeric or dimeric volatile complexes.2012-02-09
201200353526-11 Bicyclic Ketolide Derivatives - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:2012-02-09
20120035353ALIGNED NANOSTRUCTURED POLYMERS - Novel, simple methods are presented directed to the synthesis of aligned nanofibers of polyaniline and substituted derivatives on a substrate. The production of these fibers is achieved via various methods by controlling the concentration of aniline monomer or substituted aniline derivatives or an oxidant in the reaction medium and maintaining said concentration at a level much lower than conventional polyaniline synthesis methods. Methods are disclosed relating to the use of a permeable membrane to control the release of a monomer and/or oxidant as well as a bulk polymerization method.2012-02-09
20120035354MATERIALS AND METHODS FOR THE MODIFICATION OF PLANT LIGNIN CONTENT - Novel isolated polynucleotides and polypeptides associated with the lignin biosynthetic pathway are provided, together with genetic constructs including such sequences. Methods for the modulation of lignin content, lignin structure and lignin composition in target organisms are also disclosed, the methods comprising incorporating one or more of the polynucleotides of the present invention into the genome of a target organism.2012-02-09
20120035355BLEACHED DEXTRIN AND METHODS OF FORMING SAME - Bleached dextrin compositions, methods of forming the same, and products formed therefrom. The composition comprises a dextrin-based composition or slurry, a caustic agent, and an oxidant. The caustic agent may include sodium hydroxide. The oxidant may include hydrogen peroxide.2012-02-09
20120035356Hydroxycarboxylic Acids and Salts - Compositions which inhibit corrosion and alter the physical properties of concrete (admixtures) are prepared from salt mixtures of hydroxycarboxylic acids, carboxylic acids, and nitric acid. The salt mixtures are prepared by neutralizing acid product mixtures from the oxidation of polyols using nitric acid and oxygen as the oxidizing agents. Nitric acid is removed from the hydroxycarboxylic acids by evaporation and diffusion dialysis.2012-02-09
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