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06th week of 2013 patent applcation highlights part 38
Patent application numberTitlePublished
20130035397Anti-Viral Compounds - Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.2013-02-07
20130035398FUNCTIONALIZED FULLERENES AS A BIOMASS STIMULANT AND A LIFE EXTENSION AGENT - Methods of stimulating an increase in biomass by stimulating the growth, lifespan and/or reproduction of organisms such as fungi, algae, plants, and other aquatic organisms are provided by applying an effective amount of functionalized fullerenes. For example, polyhydroxy fullerenes are effective at low levels of promoting the increase in biomass.2013-02-07
20130035399MARKED INORGANIC ADDITIVES - The subject matter of the present invention is marked inorganic additives, a method for their production and also their use.2013-02-07
20130035400Metal Effect Pigments Coated with SIO2, Method for Producing Said Metallic Effect Pigments and Use - The invention relates to a method for coating metallic effect pigments with silicon oxide, in which alkoxysilane(s) and/or silicon halide(s) in organic solvent are reacted with water in the presence of metallic effect pigments, where the reaction includes at least two steps, where (a) the reaction is carried out with addition of acid in a first step and with addition of base in a second step or where (b) the reaction is carried out with addition of base in a first step and with addition of acid in a second step. The invention further relates to the coated metallic effect pigments producible by way of the method of the invention, and also to the use thereof.2013-02-07
20130035401NOVEL SELF-REVERSIBLE REVERSE LATEX, AND USE THEREOF AS A THICKENING AGENT IN A COSMETIC COMPOSITION - A self-reversible reverse latex, and its use as a thickener. The self-reversible reverse latex includes: 50%-70% of a cross-linked polyelectrolyte obtained by the polymerization of a monomer of formula (I), with R1 being 8 to 20 carbon atoms and 1≦n≦30 for a neutral monomer, and a monomer having an acid function; 4%-10% of a water-in-oil emulsifier; 1%-10% of an oil-in-water emulsifier including a surface-active composition (C); 15%-45% oil; and 0%-5% water. Composition (C) is 10%-50% composition (C2013-02-07
20130035402BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF - Novel biodegradable polyesteramides derived from optionally functionalized diacids and optionally functionalized diamines or from compounds having both optionally functionalized acid and optionally functionalized amine moieties, their preparation, and absorbable surgical articles fabricated therefrom, such as monofilament and multifilament sutures, films, sheets, plates, clips, staples, pins, screws, stents, stent coatings, packaging materials, and other implantable surgical devices, and the like, are described herein.2013-02-07
20130035403CELLS, NUCLEIC ACIDS, ENZYMES AND USE THEREOF, AND METHODS FOR THE PRODUCTION OF SOPHOROLIPIDS - The invention relates to cells, nucleic acids, and enzymes, the use thereof for producing sophorolipids, and methods for producing sophorolipids.2013-02-07
20130035404Integrated Analyses of Breast and Colorectal Cancers - Genome-wide analysis of copy number changes in breast and colorectal tumors used approaches that can reliably detect homozygous deletions and amplifications. The number of genes altered by major copy number changes—deletion of all copies or amplification of at least twelve copies per cell—averaged thirteen per tumor. These data were integrated with previous mutation analyses of the Reference Sequence genes in these same tumor types to identify genes and cellular pathways affected by both copy number changes and point alterations. Pathways enriched for genetic alterations include those controlling cell adhesion, intracellular signaling, DNA topological change, and cell cycle control. These analyses provide an integrated view of copy number and sequencing alterations on a genome-wide scale and identify genes and pathways that are useful for cancer diagnosis and therapy.2013-02-07
20130035405COMPOSITION AND METHOD FOR ENHANCING THE PRODUCTION OF CRYSTAL AGGLOMERATES FROM A PRECIPITATION LIQUOR - The present invention relates to compositions and methods to increase the output of a high quality product from the precipitation liquor crystallization process exemplified through the aluminum hydroxide recovery processes such as the Bayer process. The invention is a method of increasing the size of precipitates from a liquor. The invention in one embodiment relates to the use of a crystal growth modifier compositions added to the precipitation process to increase the particle size distribution of the precipitated alumina trihydrate.2013-02-07
20130035406SYNTHESIS OF DME USING A FLUID PLURALIZED BED REACTOR - This invention discloses a method for making a dimethylether (DME) product from a synthesis gas (syngas) in the presence of a catalyst in a fluid pluralized bed reactor operating in the gas phase. The reactions generate a significant amount of heat and the heat management is balanced between supplying quench recycle syngas to the pluralized sections along the reactor and also by controlling the preheat temperature of the reactant streams. Gas phase fluidization of the catalyst is controlled so that the pluralized reactive zones are maintained in a backmix configuration.2013-02-07
20130035407USE OF POLYSILOXANES COMPRISING BRANCHED POLYETHER MOIETIES FOR THE PRODUCTION OF POLYURETHANE FOAMS - The present invention relates to the use of polyethersiloxane compounds branched within the polyether moiety and preferably containing carbonate groups, as foam stabilizers in the production of polyurethane foams.2013-02-07
20130035408ALKYL CARBONATE ENDCAPPED POLYETHER SILOXANES AND PREPARATION THEREOF - The present invention provides polysiloxane-polyether copolymers comprising at least one polyether moiety, characterized in that there is at least one polyether moiety capped with at least one —O—C(O)—O—R″ unit where R″ is identical or different alkyl moieties, a process for preparation thereof and use thereof, especially for polyurethane foam production.2013-02-07
20130035409POLYSILOXANE POLYETHER COPOLYMERS HAVING (POLYETHER)MOIETIES COMPRISING CARBONATE GROUPS AND THEIR USE AS STABILIZERS FOR THE PRODUCTION OF POLYURETHANE FOAMS - The present invention relates to polysiloxane polyether copolymers which comprise at least one (polyether) moiety which comprises at least one unit —O—C(O)—O—, to a process for the production of the polysiloxane polyether copolymers, and also to the use of the polysiloxane polyether copolymers as stabilizers in the production of polyurethane foams, and also to polyurethane foams and items therefrom which are obtainable through the process.2013-02-07
20130035410BLOWING AGENT COMPOSITION OF HYDROCHLOROFLUOROOLEFIN - A blowing agent for thermosetting foams is disclosed. The blowing agent is predominately the trans isomer of the hydrochlorofluoroolefin (HCFO) HFCO-1233zd alone or in combination with a hydrofluoroolefin (HFO), hydrofluorocarbon (HFC), hydrochlorofluoroolefin (HCFO), a hydrocarbon. The blowing agent is effective as a blowing agent in the manufacture of thermosetting foams.2013-02-07
20130035411THERMAL EXPANSION CONTROL EMPLOYING PLATELET FILLERS - Bilayer platelet fillers are employed to compensate for a positive coefficient of thermal expansion (CTE) of an embedding polymeric material, or even to provide a composite structure having a negative CTE to eliminate or alleviate thermomechanical stress and/or delamination during thermal cycling. A bilayer platelet includes two joined layers having different CTEs. The CTE mismatch induces bending of the bilayer platelets, thereby causing cavities at temperatures lower than the joining temperature at which the bilayers are joined. The decrease in the volume of the polymeric material and the bilayer platelets at low temperatures is compensated by an accompanying increase in the volume of the cavities so that the composite structure has a temperature independent volume, a low net CTE, or even a negative CTE.2013-02-07
20130035412PRODUCTION AND USE OF METAL SALTS OF ALKYL OXIDE AND/OR ARYL ALKYL OXIDE OLIGOMERS AND POLYMERS WITH ACID END GROUPS IN THE PRODUCTION OF POLYURETHANE SYSTEMS - The invention relates to a catalyst system that is suitable for catalyzing the production of polyurethane foams. The catalyst system is characterized in that said system contains a metal salt of an alcohol that is modified with an acid end group.2013-02-07
20130035413CELLULAR STRUCTURES AND VISCOELASTIC POLYURETHANE FOAMS - The present invention discloses a structure comprising a plurality of three dimensional cells, wherein each cell comprises exterior walls defining an interior void wherein the walls comprise a plurality of struts and windows, the struts forming borders for the plurality of windows, wherein the struts have a plurality of pores. The present invention further discloses a viscoelastic foam having a ratio of elastic modulus (E′) at 20° C. to 25% compression force deflection (CFD) of 25 to 125.2013-02-07
20130035414HIGH REFRACTIVE INDEX POLYMER COMPOSITION FOR OPTHALMIC APPLICATIONS - A monomer for a polymerisable composition is described, the monomer having the formula (I) wherein: R2013-02-07
20130035415IN SITU BULKING COMPOSITION - The present invention relates to a hydrated, biocompatible tissue-augmentation compound and methodology for its implantation into mammalian tissue. The tissue-augmentation compound is comprised of: living tissue, optionally body derived fluids, and at least one NCO-terminated hydrophilic urethane prepolymer derived from an organic polyisocyanate, and oxyethylene-containing diols or polyols in which essentially all of hydroxyl groups are capped with polyisocyanate.2013-02-07
20130035416POLYACETAL RESIN COMPOSITION, METHOD FOR PRODUCING THE SAME, AND MOLDED ARTICLE - A polyacetal resin composition and molded article having a high metallic gloss, small change in a color tone according to the viewing angle, high weld performance, and high mechanical properties can be provided in which the amount of formaldehyde to be produced in molding and recycle is suppressed, the mold deposit is improved, and the repeated impact resistance after aging is high.2013-02-07
20130035417PROCESS TO INERT NON-SWELLING CLAYS - A process to inert non-swelling clays in at least one mineral component intended for the preparation of a hydraulic composition, including the addition, to the hydraulic composition, to the mineral component or to one of the other constituents of the hydraulic composition, of an organic molecule having a cationic charge density strictly less than 0.5 meq/g and including at least two atoms each being capable of forming at least one hydrogen bond.2013-02-07
20130035418PROCESS FOR THE PREPARATION OF MONODISPERSE POLYMER PARTICLES - A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerization in the presence of a steric stabilizer. The resulting swollen seed particles are characterized by the particle mode diameter.2013-02-07
20130035419METHODS FOR DISPERSING CARBON NANOTUBES AND COMPOSITIONS USED FOR THE METHODS - The present invention refers to a method of dispersing carbon nanotubes in a thermosetting resin. The method comprises: (a) contacting the carbon nanotubes with a dispersant in a solvent to form a dispersion mixture, wherein the dispersant is a graft polymer comprising a polymeric backbone and a side chain grafted to the polymeric backbone; and (b) adding the thermosetting resin to the dispersion solution to form a resin blend. The present invention also refers to a composition used for the method.2013-02-07
20130035420Resin For Use In A Coating Composition - A coating system comprises a substrate and a cured film disposed on the substrate and formed from a coating composition. The coating composition comprises a solvent component and a resin. The resin comprises a reaction product of a polyolefin and an oligomer or polymer. The polyolefin, different from the oligomer or polymer, has a functional group that is reactive with the oligomer or polymer and the functional group is selected from acrylate, methacrylate, carboxyl, hydroxyl, epoxide, anhydride and isocyanate functional groups. The oligomer or polymer and the polyolefin are at least partially immiscible in solution at ambient temperature. The oligomer or polymer is grafted with the polyolefin to form the resin.2013-02-07
20130035421COATING COMPOSITIONS EXHIBITING CORROSION RESISTANCE PROPERTIES, RELATED COATED SUBSTRATES, AND METHODS - Coating compositions are disclosed that include corrosion resisting particles such that the coating composition can exhibit corrosion resistance properties. Also disclosed are substrates at least partially coated with a coating deposited from such a composition and multi-component composite coatings, wherein at least one coating later is deposited from such a coating composition. Methods and apparatus for making ultrafine solid particles are also disclosed.2013-02-07
20130035422Method For Qualitatively And Quantitatively Identifying Bulk Goods - Identification and quantification of mass-produced goods in articles, a dye-containing polymer dispersion having been added to the mass-produced goods. The polymer dispersions contain particles which are coded by a mixture of dyes, and the polymer dispersion particles are quantitatively determined.2013-02-07
20130035423RAPID HYDRAULIC BINDER FOR CONCRETE PARTS AND STRUCTURES - A rapid hydraulic binder includes cement; a setting and hardening accelerator including hydrated calcium silicate seeds, a first superplasticizer and a second superplasticizer different from the first superplasticizer and having a maximum fluidizing action at 20° C. after the maximum fluidizing action at 20° C. of the first superplasticizer.2013-02-07
20130035424METHOD AND SYSTEM FOR PROCESSING UNFERMENTED GRAIN SOLIDS AND UTILIZING THE PRODUCTS THEREOF - A system and method of producing a filler material for combining with a polymer in a product may comprise providing an initial mixture including wetted unfermented grain solids, oxidizing the initial mixture to form a treated mixture, removing moisture from the treated mixture, and combining the treated material with a polymer into a composition.2013-02-07
20130035425FLUID ACTIVATABLE ADHESIVES AND FLUIDS FOR ACTIVATING SAME FOR USE WITH LINER-FREE LABELS - Fluid activatable adhesive compositions and activating fluid(s) for activating the adhesive composition are described herein. The adhesive compositions contain at least two polymers with different hydrophilicities. The hydrophilic polymer has quick tack when exposed to a hydrophilic solvent, such as water or other aqueous solvent, while the hydrophobic polymer provides strong adhesion to a paper or polymeric substrate. The adhesive composition may contain particulate fillers which enable fast exhaustion of the activation fluid out of the adhesive when applied to a substrate, thereby allowing the hydrophobic polymers of the adhesive composition to achieve strong adhesion of the liner-free label to the paper or polymeric substrate. The particulate fillers may also function as anti-blocking agents when liner-free label media are tightly wound in a roll. The adhesive compositions described herein may be used not only on paper, cardboard, and metal, but also on glass and plastics commonly used in commercial applications.2013-02-07
20130035426THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION - The present invention provides a thermoplastic polymer composition containing a particular phenol compound or organic phosphorous compound, trehalose and a thermoplastic polymer, as well as a stabilizer composition containing a particular phenol compound or organic phosphorous compound and trehalose. A combined use of a particular phenol compound or organic phosphorous compound and trehalose can improve processing stability of a thermoplastic polymer composition.2013-02-07
20130035427THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER - The present invention provides a thermoplastic polymer composition containing a particular phenol compound or organic phosphorous compound, glucose and a thermoplastic polymer, as well as a processing stabilizer containing a particular phenol compound or organic phosphorous compound and glucose. A combined use of a particular phenol compound or organic phosphorous compound and glucose can improve processing stability of a thermoplastic polymer composition.2013-02-07
20130035428Phase Change Inks Containing Oxazoline Compounds and Polyterpene Resins - Disclosed is a phase change ink comprising (a) a crystalline oxazoline compound; and (b) an amorphous polyterpene resin.2013-02-07
20130035429TRANSPARENT AND FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSITE AND MOLDED ARTICLE - A transparent and flame-retardant aromatic polycarbonate resin composite is provided. A transparent and flame-retardant aromatic polycarbonate resin composite includes (A) 100 parts by mass of a transparent aromatic polycarbonate resin composed of 99 percent by mass to 50 percent by mass of an aromatic polycarbonate resin-A with a viscosity-average molecular weight (Mv) of 3×102013-02-07
20130035430AQUEOUS COATING COMPOSITION FOR IMPROVED LIQUID STAIN REPELLENCY - The present invention relates to a coating composition, especially, relates to an aqueous coating composition with improved liquid stain repellency, it has a fraction of critical pigment volume concentration of from 35% to 110%, and comprises (i) pigment composition, including 15 wt. %-100 wt. %, in percentage by weight based on the dry weight of the pigment composition, polymer-encapsulated pigment; and 0-85 wt. %, in percentage by weight based on the dry weight of the pigment composition, un-encapsulated pigment; and (ii) 0.01 wt. %-5 wt. %, in percentage by dry weight based on the wet weight of the aqueous coating composition, at least one paraffin wax emulsion.2013-02-07
20130035431ALKYL AROMATIC PLASTICIZERS AND METHODS OF MAKING - Provided are compounds of the formula:2013-02-07
20130035432PROCESS FOR THE PRODUCTION OF PHYLLOSILICATE DISCS HAVING A HIGH ASPECT RATIO - The present invention relates to a process for the production of phyllosilicate platelets having a high aspect ratio, to a phyllosilicate platelet obtainable by the process according to the invention, to the use of phyllosilicate platelets according to the invention in the production of a composite material, of a flameproof barrier or of a diffusion harrier, and to a composite material comprising or obtainable using phyllosilicate platelets according to the invention.2013-02-07
20130035433Pressure Sensitive Adhesives Containing Reactive, Surface-Modified Nanoparticles - Acrylic copolymer pressure sensitive adhesive compositions containing surface-modified nanoparticles are described. The surface-modified nanoparticles are based on nanoparticles having a silica surface and a plurality of silane surface-modifying groups covalently bonded to the silica surface. Although some of the silane surface modifying groups may be non-reactive, at least 25 mole percent, and up to 100 mole percent, of the silane surface-modifying groups are reactive silane surface-modifying groups.2013-02-07
20130035434ZINC IONOMER RUBBER ACTIVATOR - Curable rubber compositions and cured articles are based on the use of zinc activator compositions for the sulfur cure. Activator compositions contain zinc and a polymeric component having a plurality of COOH groups, at least some of which are neutralized with the zinc. With polymeric zinc activators, sulfur cure can be activated at levels of zinc below those used in conventional systems.2013-02-07
20130035435SILYLATED AMINO RESINS - The present invention relates to silylated amino resins, to processes for preparing them, to their use, and to coating compositions comprising them.2013-02-07
20130035436COMPOSITION AND MANUFACTURING METHODS FOR GRIPS - A composition for use in grips is disclosed. The composition may be used, for example, in making a golf club grip. The disclosed grip provides for improved shock absorption and other beneficial properties. In one embodiment the comprises a cross-linked composition of from about 40% by weight to about 80% by weight of one or a combination of a first material selected from the group consisting of butyl rubber, nitrile rubber, ethylene propylene rubber and chloroprene rubber, and from about 10% by weight to about 50% by weight of one or a combination of a second material selected from the group consisting of ethylene-propylene-diene copolymer (EPDM), polyurethane, ethylene-vinyl acetate copolymer, polypropylene and cork.2013-02-07
20130035437RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS - Vulcanizates with desirable properties can be obtained from compositions incorporating polymers that include hydroxyl group-containing aryl functionalities, silica or other particulate filler(s) that contain or include oxides of silicon and a group or compound that can act to covalently bond the filler particles and the polymer. The group can be provided as a substituent of the filler particle, or a discreet compound can be provided in the composition.2013-02-07
20130035438METHOD FOR PREPARING POLYETHYLENE WITH HIGH MELT STRENGTH - The present invention is an ethylene-based polymer comprising reacting a polyethylene resin with an alkoxy amine derivative corresponding to the formula:2013-02-07
20130035439METHOD FOR PRODUCING PAVEMENTS FOR OUTDOOR FACILITIES, THE SURFACE FINISHING MATERIAL USED THEREIN, AND THE PAVEMENTS FOR OUTDOOR FACILITIES OBTAINED THEREBY - The present invention concerns a method for producing pavements for outdoor facilities, the surface finishing material used therein, and the pavements for outdoor facilities obtained thereby.2013-02-07
20130035440POLYARYLENE SULFIDE RESIN COMPOSITION - To provide a polyarylene sulfide resin composition which contains decreased amount of chlorine, which has a high fluidity and generates small flashes at the time of molding, which has an excellent heat resistance, which can resist heat-processing under the condition of a high temperature, which has moldability at a low mold temperature, a molded article of which has an extremely small change in surface hue before and after reflow. The resin composition is obtained by blending: 100 parts by weight of a polyarylene sulfide resin (A) containing 500 to 2,000 ppm of chlorine and having 10 to 200 Pa·s of melt viscosity, 10 to 100 parts by weight of a liquid crystalline polyester amide resin (B), and 5 to 250 parts by weight of glass fiber (C) containing 100 ppm or less of nitrogen, and having a total chlorine content of 950 ppm or less,2013-02-07
20130035441POLYCARBONATE COMPOSITIONS HAVING ENHANCED OPTICAL PROPERTIES, METHODS OF MAKING AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITIONS - In some embodiments, a composition comprises a bisphenol-A polycarbonate, wherein a molded article of the composition has transmission level greater than or equal to 90.0% at 2.5 mm thickness as measured by ASTM D1003-00 and a yellow index (YI) less than or equal to 1.5 as measured by ASTM D1925.2013-02-07
20130035442ELASTIC PROPYLENE-ALPHA-OLEFIN COPOLYMER COMPOSITIONS AND PROCESSES TO PRODUCE THEM - Provided are elastic propylene-alpha olefin blocky copolymers. In one form, the elastic propylene-alpha olefin blocky copolymer includes an α-olefin content from 12 to 25 wt % and having a propylene crystallinity less than 30 J/g, a Tm <100° C. and a Tg >−45° C., wherein said copolymer has blocky propylene segments with r2013-02-07
20130035443METHOD OF MAKING A BLOCKED POLYMER WITH A SILOXANE LINKING GROUP - Carbanionic polymer chains that contain polyene mer can be provided with a block derived from one or more ethylenically unsaturated functional monomers after being reacted to include, at their respective termini, one or more, although preferably one, unit that is the radical of a cyclic compound, the ring structure of the cyclic compound comprising silicon atoms alternating with O, S or N atoms.2013-02-07
20130035444POLYETHYLENE WITH HIGH MELT STRENGTH FOR USE IN FILMS - The present invention is a method for producing a film particularly well suited for shrink film applications, said method comprising the steps of selecting a target polyethylene resin and then increasing the melt strength of the polyethylene resin by reacting the polyethylene resin with an alkoxy amine derivative, and then forming a film from the reacted target polyethylene.2013-02-07
20130035445METHOD OF MAKING POLYMERIC POLYMER CONTAINING POLY(OXYETHYLENE)-AMINE - A polymeric polymer is prepared from poly(oxyethylene)-amine and a linker, for example, poly(styrene-co-maleic anhydride) (SMA) or dianhydride. The polymeric polymer can chelate silver ions and reduce them to silver atoms which are dispersed as nanoparticles. No additional reducing agent is needed and more than 30% of solid content of the nanoparticles solution can be achieved without aggregation. The prepared silver nanoparticles are both hydrophilic and hydrophobic and therefore are compatible with polymers.2013-02-07
20130035446PHOTOALIGNING MATERIAL - The present invention relates to polymer, homo- or copolymer or oligomer for the photoalignment of liquid crystals comprising a main chain and a side chain, wherein the side chain comprises a difluoromethylene group, compositions thereof, and its use for optical and electro optical devices, especially liquid crystal devices (LCDs).2013-02-07
20130035447POLYIMIDE FILM - The present invention provides a polyimide film having a good transparency and also an excellent thermal resistance so that it is useful in a transparent conductive film, TFT substrate, a flexible printing circuit substrate, and the like.2013-02-07
20130035448BIOMASS-RESOURCE -DERIVED POLYURETHANE, METHOD FOR PRODUCING SAME, AND BIOMASS-RESOURCE-DERIVED POLYESTER POLYOL - The invention relates to a method for producing a biomass-resource-derived polyurethane, which comprises: reacting a dicarboxylic acid and an aliphatic diol to produce a polyester polyol; and reacting the polyester polyol and a polyisocyanate compound, wherein the dicarboxylic acid contains at least one component derived from biomass resources, a content of an organic acid in the dicarboxylic acid is more than 0 ppm and not more than 1,000 ppm relative to the dicarboxylic acid, and a pKa value of the organic acid at 25° C. is not more than 3.7.2013-02-07
20130035449METHOD FOR PREPARING BIODEGRADABLE POLYMER MATERIALS, BIODEGRADABLE POLYMER MATERIALS AND PRODUCT FOR FIXING BONE - Disclosed are a method for preparing biodegradable polymer materials, biodegradable polymer materials, and a product for fixing bone. The method includes a complex preparing step of preparing polylactide stereoisomeric complex by using a polymer having weight-average molecular weight more than 100,000 g/mol; a molding step of compression-molding the complex; a cooling step of cooling the compression-molded complex; and an extruding step of solid state extruding the cooled complex. Biodegradable polymer materials prepared by the method may be applied to a product for fixing bone or spine requiring high strength. Biodegradable polymer materials may have no corrosion in the body, may require no additional operation for removal after healing bones and tissues, and may prevent stress shielding.2013-02-07
20130035450OUTER CASING AND METHOD FOR PRODUCING THE SAME - An outer casing for an electric device which is a molded article of a environmental resin wherein poly(lactic acid) and/or a lactic acid copolymer is used, is constituted by molding a flame-retarded resin composition including a resin component containing poly(lactic acid) and/or the lactic acid copolymer as a main ingredient, and silica-magnesia catalyst particles as a flame retardance-imparting component which imparts flame retardance, wherein the content of the silica-magnesia catalyst particles is 0.5% by weight or more and 9.0% by weight or less of the total weight of the flame-retarded resin composition. The silica-magnesia catalyst particles preferably have an average particle diameter of 10 μm or less.2013-02-07
20130035451Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds - Disclosed are phosphinic acid compounds of formula I, II or III2013-02-07
20130035452POLYSILOXANE BLOCK COPOLYMERS AND USE THEREOF IN COSMETIC FORMULATIONS - The present invention relates to specific polyorganosiloxane block copolymers obtainable by radical polymerization, and to the use of the polyorganosiloxane block copolymers for the preparation of cosmetic or pharmaceutical compositions or body care compositions.2013-02-07
20130035453POLYURETHANE RESIN - An object of the present invention is to provide a non-solvent type polyurethane resin which may be preferably used for a curing composition having physical properties after curing of low modulus and high elongation and which is excellent in adhesion, physical properties, handling property and storage stability and a process for producing the polyurethane resin without difficulty and at low cost. The polyurethane resin is obtained by reacting a urethane prepolymer obtained by reacting a mixture of a monool and a polyol, having on average 1.3 to 2.1 of terminal hydroxyl groups, and a polyisocyanate, and a compound having a crosslinkable silyl group, an imino group and an amino group in a molecule.2013-02-07
20130035454POLYBENZIMIDAZOLE-POLYETHERKETONEKETONE BLENDS AND MISCIBLE BLENDS - A process for producing a solution blend of a polybenzimidazole (PBI) and a polyetherketoneketone (PEKK). The PBI is mixed with sulfuric acid at a temperature between 40° C. and 80° C. for 30 minutes to 2 hours to produce a PBI solution then cooled to room temperature to form a cooled PBI solution. Then PEKK is added to the cooled PBI solution to form a mixture and that mixture is stirred from 30 minutes to 2 hours at room temperature to form a stirred mixture. The stirred mixture is poured into an excess of water being stirred swiftly to form an aqueous mixture. The aqueous mixture is filtered to produce a blend. The blend is washed with water and dried. The resulting blend can yield a blend in all proportion from 1/99 PBI/PEKK to 99/1 PBI/PEKK.2013-02-07
20130035455CURABLE COMPOSITION, CURED PRODUCT, AND METHOD FOR USING OF CURABLE COMPOSITION - A curable composition that includes (A) a silane compound copolymer that includes a specific repeating unit, (B) a silane coupling agent having a reactive cyclic ether structure, and (C) a curing agent so that the mass ratio “(A):((B)+(C))” of the silane compound copolymer (A) to the silane coupling agent (B) and the curing agent (C) in total is 95:5 to 70:30, a cured product obtained by curing the curable composition, and method for using of the curable composition as an optical device-securing adhesive or an optical device sealing material, are disclosed. The curable composition produces a cured product that does not show coloration (i.e., does not show a deterioration in transparency) even when exposed to high-energy light or subjected to a high temperature, exhibits excellent transparency for a long time, and has high adhesion even at a high temperature. The curable composition may be used to form an optical device-securing material, and may suitably be used as an optical device-securing adhesive or an optical device sealing material.2013-02-07
20130035456Phosphazene Blocked Imidazole as Latent Catalyst for Epoxy Resins - Epoxy resin compositions utilizing phosphazene blocked azole compounds as curing catalyst are provided. Also provided are epoxy resins cured with phosphazene blocked azole compounds and methods of making cured epoxy resins using curing catalysts of phosphazene blocked azole compounds.2013-02-07
20130035457PROCESS FOR PREPARING A BLOCK COPOLYMER - The present invention relates to a process for preparing a block copolymer comprising poly-arylene ether and polyalkylene oxide blocks, comprising the reaction of an HO-terminated poly-arylene ether with a monomeric alkylene oxide.2013-02-07
20130035458High Activity Catalyst Compositions Containing Silicon-Bridged Metallocenes with Bulky Substituents - The present invention discloses catalyst compositions employing silicon-bridged metallocene compounds with bulky substituents. Methods for making these silicon-bridged metallocene compounds and for using such compounds in catalyst compositions for the polymerization of olefins also are provided.2013-02-07
20130035459REACTOR - The present invention relates to a reactor, and in particular to a slurry loop polymerisation reactor which comprises: 2013-02-07
20130035460Process for Making Ethylene Interpolymers and Interpolymers Made Thereby, and Compositions and Electrical Devices Containing Such Interpolymers - The invention relates to a continuous polymerization process for preparing a random ethylene interpolymer which comprises: (A) polymerizing ethylene, and an α-olefin comonomer selected from propylene and/or 1-butene, and mixtures thereof, under continuous random polymerization conditions in the presence of single site catalyst system employing an ionic activator having cyclic ligands shielding a central charge bearing atom, at a temperature of 140° C. to 250° C. at a conversion of ethylene of 80 to 99% and a comonomer conversion of from at least 20%; and (B) devolatilizing the polymer to provide an ethylene copolymer having a density of from 0.85 to 0.92 g/cm2013-02-07
20130035461FLUORINE AND EPOXY GROUP-CONTAINING COPOLYMER, AND METHOD FOR PRODUCING SAME - Provided is a fluorine- and epoxy group-containing copolymer with excellent workability at room temperature, high water-repellency, and excellent characteristics as a water vapor barrier. Also provided is an efficient method for producing said copolymer. The fluorine and epoxy group-containing copolymer is characterized by containing at least a monomer unit represented by general formula (1): {Therein, R2013-02-07
20130035462ETHYLENIC POLYMERIZATION CATALYST AND METHOD FOR MANUFACTURING ETHYLENIC POLYMER - A catalyst for homopolymerization of ethylene or copolymerization of ethylene and an α-olefin comprises a complex represented by Formula (1):2013-02-07
20130035463Catalyst Systems And Methods For Using Same To Produce Polyolefin Products - Catalyst systems and methods for making and using the same. The catalyst system can include a single site catalyst compound, a support comprising fluorinated alumina, and an aluminoxane. The aluminoxane can be present in an amount of about 10 mmol or less per gram of the support.2013-02-07
20130035464Semiconducting Compounds and Devices Incorporating Same - Disclosed are molecular and polymeric compounds having desirable properties as semiconducting materials. Such compounds can exhibit desirable electronic properties and possess processing advantages including solution-processability and/or good stability.2013-02-07
20130035465RADICAL POLYMERIZABLE RESIN, RADICAL POLYMERIZABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF - Provided is a radically polymerizable resin which has a low viscosity, has excellent workability, and is rapidly cured upon application of heat and/or light to form a cured product having excellent flexibility and thermal stability. The radically polymerizable resin composition is obtained by cationic polymerization of an oxetane-ring-containing (meth)acrylic ester compound represented by following Formula (1) alone or in combination with another cationically polymerizable compound. In Formula (1), R2013-02-07
20130035466METHOD FOR PRODUCING A SKIN LAYER OF A FLEXIBLE, ELASTOMERIC, THERMOSET, PHASE-SEPARATED POLYURETHANE MATERIAL - The thermoset, phase-separated polyurethane material of the flexible skin layer is produced from a reactive mixture which is made of one or more isocyanate compounds and isocyanate reactive compounds which comprise one or more polyol compounds, flexibilisers, chain extenders and/or crosslinkers and amine-initiators. Apart from at least one crosslinking amine-initiator, these amine-initiators further comprise at least one extender amine-initiator which has a functionality of 2 and a molecular weight of less than 300 and which corresponds to formula (I)2013-02-07
20130035467HYBRID POLYESTER-POLYETHER POLYOLS - A process for preparing a hybrid polyester-polyether polyol comprises contacting a carboxyl group-containing component and an epoxide, optionally in the presence of one or more of a double metal cyanide catalyst, a superacid catalyst, a metal salt of a superacid catalyst and/or a tertiary amine catalyst, under conditions such that a hybrid polyester-polyether polyol is formed. The hybrid polyester-polyether polyol offers the advantages of both ester and ether functionalities when used in a polyurethane formulation, thus enhancing physical properties. The process results in products having narrow polydispersity, a low acid number and unsaturation, and reduced byproduct formation, particularly when the double metal cyanide catalyst is employed.2013-02-07
20130035468THERMOPLASTIC RESIN WITH HIGH THERMAL CONDUCTIVITY - Provided is a thermoplastic resin having excellent thermal conductivity, in which thermoplastic resin a change in number average molecular mass caused by progress of polymerization occurring when the thermoplastic resin material is melted and a change in thermal conductivity caused by the change in number average molecular mass are low. The thermoplastic resin has (A) a specific structure and (B) ends of molecular chains sealed by a monofunctional low molecular weight compound. The resin itself has excellent thermal conductivity. The change in number average molecular mass becomes small during melting of the thermoplastic resin material, so that the change in thermal conductivity of the resin itself becomes small.2013-02-07
20130035469Antimicrobial Peptides and Methods of Use - Disclosed herein are novel antimicrobial peptides with useful, improved, or superior properties such as antimicrobial activity, specificity, resistance to degradation desirable levels of hemolytic activity, and therapeutic index against a broad range of microorganisms including gram-negative and gram-positive bacteria and other organisms having a cellular or structural component of a lipid bilayer membrane. Also provided are methods of making and using such peptides to control microbial growth and in pharmaceutical compositions for treatment or prevention of infections caused by such microorganisms. Certain peptides result from structure-based rational design relating to antimicrobial peptide V681, with single D-/L-amino acid substitutions or charged residue substitutions in or near the center of the peptide on the nonpolar or polar face. Some peptides contain one or more (or all) amino acids in the D configuration. Compositions disclosed herein have useful clinical potential as antibiotics including broad spectrum antibiotics.2013-02-07
20130035470CRYSTALLINE OXIDIZED GLUTATHIONE AND PRODUCTION METHOD THEREFOR - Provided is a novel crystal of oxidized glutathione hexahydrate. Crystal of oxidized glutathione hexahydrate is produced by cooling an aqueous solution containing oxidized glutathione to 15° C. or lower to precipitate a crystal of oxidized glutathione hexahydrate.2013-02-07
20130035471Tetrameric Streptavidin Mutein With Reversible Biotin Binding Capability - The present invention relates to a new streptavidin muteins. This mutein is The muteins are capable of oligomerization to form tetramers, with relatively strong subunit interactions, dissociation constant (K2013-02-07
20130035472METHOD OF PRODUCING TRANSCRIPTS USING CRYPTIC SPLICE SITES - The invention is directed to a method of preparing a nucleic acid sequence with a modified splice site usage profile, which employs the use of a nucleic acid sequence comprising a cryptic splice donor site. The invention also provides a method of producing an alternate form of an RNA molecule encoded by a nucleic acid sequence, which nucleic acid sequence comprises a cryptic splice donor site, a heterologous nucleic acid sequence, and a splice acceptor site.2013-02-07
20130035473COLLAGEN MIXTURE AND METHOD OF MAKING THE SAME - A collagen mixture having a portion of unhydrolyzed eggshell membrane collagen and Avian collagen.2013-02-07
20130035474COLLAGEN MIXTURE AND METHOD OF MAKING THE SAME - A collagen mixture having a portion of unhydrolyzed eggshell membrane collagen and Avian collagen.2013-02-07
20130035475Methods for Identifying Compounds That Modulate Ion Channel Activity of a Kir Channel - Methods for identifying compounds that modulate the ion channel activity of a Kir channel are provided. Methods for identifying compounds that selectively modulate the ion channel activity of specific types of Kir channels based on the turret region of a Kir channel are also provided. Methods for identifying compounds to treat conditions associated with abnormal ion channel activity are also provided. Compounds including purified antibodies and methods of making antibodies which bind to the turret region of a Kir channel are provided. Purified polypeptides including at least a portion of the turret region of a Kir channel and nucleic acid sequences encoding these polypeptides are also provided.2013-02-07
20130035476CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CLUMPING FACTOR A IN COMPLEX WITH FIBRINOGEN DERIVED PEPTIDE AND USES THEREOF - The present invention discloses crystal structure of 2013-02-07
20130035477Method for Removing Endotoxin from Proteins - Disclosed is a method for removing endotoxin from proteins. Also disclosed are products made by using the method. The method may be used, for example, to produce endotoxin-free lactoferrin. Bovine milk-derived lactoferrin may be produced in commercial quantities by the method, and endotoxin-free bovine lactoferrin may be used for a variety of therapeutic uses, including improving wound healing.2013-02-07
20130035478PYRROLYSINE ANALOGS - Several different pyrrolysine analogs are disclosed in this application. Those analogs have distinct chemical and biophysical properties. Some analogs are useful in chemical ligation applications. Methods of making and using are also disclosed.2013-02-07
20130035479FUNCTIONALIZED BETA 1,6 GLUCOSAMINE DISACCHARIDES AND PROCESS FOR THEIR PREPARATION - The present invention relates to a novel process for the chemical synthesis of β-(1->6)-linked glucosamine disaccharides of the formula (1) and (intermediate) compounds relating to the process. According to further aspects the invention relates to compositions comprising the compounds and the use of the compounds in the synthesis of disaccharides and medicine.2013-02-07
20130035480FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE - Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by exchange of functional tags.2013-02-07
20130035481PRODUCTION OF 6'-O-SIALYLLACTOSE AND INTERMEDIATES - The present invention relates to a method for preparation of the trisaccharide 6′-0-sialyllactose (formula (I)) or salts thereof as well as intermediates in the synthesis and for the use of 6′-0-sialyllactose salts in pharmaceutical or nutritional compositions.2013-02-07
20130035482BISPHOSPHONATE COMPOUNDS - Novel bisphosphonate cyclic acetal compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating bone metabolism disorders, such as abnormal calcium and phosphate metabolism.2013-02-07
20130035483METHODS OF CONVERTING AMORPHOUS DRUG SUBSTANCE INTO CRYSTALLINE FORM - A method for converting an amorphous drug, such as everolimus, or other macrolide immunosuppressive drug, into a crystalline form. The method utilizes a slurry of the drug in organic liquid phase and ages the slurry to achieve the conversion.2013-02-07
20130035484INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PYRROLOBENZODIAZEPINES - A compound of formula (I): which is substantially free of any of the corresponding compound of formula (IB): methods of making such compounds, and the further transformation of such compounds.2013-02-07
20130035485PROCESS FOR THE PREPARATION AND PURIFICATION OF ETRAVIRINE AND INTERMEDIATES THEREOF - In one embodiment the present invention encompasses 4-(2,6-dichloropyrimidin-4-yloxy)-3,5-dimethylbenzonitrile (“ETHER”), 4-(4,6-dichloropyrimidin-2-yloxy)-3,5-dimethyl-benzonitrile (“ETHER C-2 isomer”), mixtures and salts thereof of. The present invention encompasses the use of ETHER and salts thereof to prepare Etravirine and Etravirine intermediates, and salts thereof. In another embodiment the present invention encompasses the use of ETHER and salts thereof to prepare debrometravirine (“DEBETV”) and salts thereof. In yet another embodiment the present invention encompasses the use of ETHER and salts thereof to prepare 4-(6-chloro-2-(4-cyanophenylamino)pyrimidin-4-yloxy)-3,5-dimethyl-benzonitrile (“ARCPBN”) and salts thereof.2013-02-07
20130035486PROCESSES FOR THE PREPARATION OF SITAGLIPTIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF - There is provided salts and polymorphs of sitagliptin, processes for the preparation thereof, and pharmaceutical composition comprising the same.2013-02-07
20130035487Bioavailable Diacylhydrazine Ligands for Modulations the Expression of Exogenous Genes via an Ecdysone Receptor Complex - The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene.2013-02-07
20130035488Stepwise Process for the Production of Alkaloid Salts - The present invention provides to an improved process for preparing alkaloid salts. In particular, the process comprises a stepwise addition of an acid to an alkaloid chosen from hydrocodone, codeine, and dihydrocodeine to form a flowable mixture of the alkaloid salt.2013-02-07
20130035489PREPARATION OF LOW IMPURITY OPIATES IN A CONTINUOUS FLOW REACTOR - The present invention relates to a novel process for preparing opiates or salts thereof. More particularly, the present invention relates to oxidizing the starting material in a continuous flow reactor, followed by either an isolation of the intermediate, or a direct reduction reaction.2013-02-07
20130035490Method For Making Donepezil - The method in accordance with the present invention has: mixing E2M, an organic solvent, a weak base, sodium dithionite, and a phase transfer catalyst to obtain an E2M mixture solution; heating the E2M mixture solution and adding water to obtain a heated E2M aqueous solution having an organic layer; and extracting the organic layer from the heated E2M aqueous solution, and condensing and drying the organic layer to obtain donepezil. Employing sodium dithionite as a reducing agent improves safety over hydrogen gas used in conventional methods and lowers the cost in contrast to the conventional noble metal catalysts that are extremely expensive. Furthermore, the method of the present invention requires only 60 minutes of reaction time to synthesize donepezil with a promising yield more than 85%, which greatly raises the efficiency and economic value of the manufacture of donepezil.2013-02-07
201300354911,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT - A 1,2,4,5-substituted phenyl compound represented by the formula (1):2013-02-07
20130035492METHOD AND PROCESS FOR PREPARATION AND PRODUCTION OF DEUTERATED OMEGA-DIPHENYLUREA - Methods and processes for preparation and production of deuterated ω-diphenylurea are disclosed. Especially, a kind of deuterated ω-diphenylurea compounds which can inhibit phosphokinase and the preparation method of N-(4-chloro-3-(trifluoromethyl)phenye-N′-(4-(2-(N-d3-methylcarbamoyl)-4-pridinyloxy)phenyl)urea are disclosed. The said deuterated diphenylurea compounds can be used for treating or preventing tumors and relative diseases.2013-02-07
20130035493Process for Preparing Form A of Atazanavir Sulfate - A process of making Form A of atazanavir sulfate comprises: a) mixing atazanavir free base with a solvent selected from the group consisting of methanol (MeOH), ethanol (EtOH), isopropanol (IPA), N-methylprrolidone (NMP) and combinations thereof; b) reacting sulfuric acid with the atazanavir free base in the mixture formed in step a) to form a reaction solution comprising atazanavir sulfate; c) mixing an antisolvent with the reaction solution; d) seeding the mixture formed in step c) with an effective amount of Form A of atazanavir sulfate to form a seeded mixture comprising Form A of atazanavir sulfate; and e) isolating Form A of atazanavir sulfate in solid form from the seeded mixture; wherein the antisolvent is selected from the group consisting of methyl tert-butyl ether (MTBE), ethyl acetate (EtOAc), acetonitrile (MeCN), isopropyl acetate (IPAc), cyclohexane, and combinations thereof. In one alternative, step c) may be performed before step b). In another alternative, step d) may be carried out concurrent with or prior to step c).2013-02-07
20130035494Process for Preparation of Ruthenium-Based Carbene Catalysts with Chelating Alkylidene Ligands - The invention relates to a method for preparation of ruthenium-based carbene catalysts with chelating alkylidene ligands (so-called “Hoveyda-type catalysts”) in a cross metathesis reaction by reacting a ruthenium-alkylidene complex with an olefin derivate in the presence of a polymer-supported cation-exchange resin (PSR) acting as a ligand (i.e. phosphine or amine) scavenger. Preferably, penta-coordinated ruthenium benzylidene or indenylidene carbene complexes are employed. The polymer-supported cation-exchange resin (PSR) may be an acidic resin (comprising sulfonic acid or carboxylic groups) or a resin containing carboxylic acid chloride (—COCl) groups or sulfonyl chloride (—SO2013-02-07
20130035495PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES - The invention relates to a process for the preparation of formula (I) which process comprises a) reacting a compound of formula (II), wherein X is chloro or bromo, with an organometallic species to (III), wherein X is chloro or bromo; reacting the halobenzyne with a fulvene (IV), to a compound of formula (V) wherein X is chloro or bromo; b) hydrogenating V in the presence of a suitable metal catalyst to a compound of formula (VI) wherein X is chloro or bromo; and either c1) reacting the compound of formula VI with NH3 in the presence of a catalyst comprising palladium and at least one ligand to the compound of formula (VII); and d) reacting the compound of formula VII in the presence of a base with a compound of formula (VIII), to the compound of formula I; or c2 reacting the compound of formula (VI) in the presence of a copper catalyst and a ligand with the compound of formula (VIIIa), to the compound of formula (I).2013-02-07
20130035496PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES - The invention relates to a process for the preparation of the compound of formula (I), which process comprises a) reacting a compound of formula (II), wherein X is chloro or bromo, with an organometallic species in an inert atmosphere to a halobenzyne of formula (X), reacting the halobenzyne of formula X so formed with cyclopentadiene to (III), b) reacting III in the presence of an inert solvent with an oxidant to (IV), c) reacing IV in the presence of a Lewis acid and a hydride source to (V), d) reacting V in the presence of an oxidizing agent, a base and an inert solvent to (VI), e) converting VI in the presence of a phosphane and CCL2013-02-07
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