06th week of 2015 patent applcation highlights part 52 |
Patent application number | Title | Published |
20150038593 | DISAGGREGATION OF AGGREGATED NANODIAMOND CLUSTERS - The present invention is directed to methods of disaggregating nanodiamond clusters, especially those clusters typically produced from detonation syntheses, the nanodiamond particles and dispersions produced from these disaggregation processes, and compositions derived from these nanodiamond particles and dispersions. | 2015-02-05 |
20150038594 | ORAL DISPERSIBLE FILMS - Described herein are orodispersible films comprising a film forming hydrophobic polymer, a disintegrant, a plasticizer and a stabilizer. | 2015-02-05 |
20150038595 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Serum albumin, Protein S100-B, Glial cell line-derived neurotrophic factor, Resistin, Serum amyloid A protein, Hydrocortisone, Parathyroid hormone, and Tissue Plasminogen Activator as diagnostic and prognostic biomarkers in renal injuries. | 2015-02-05 |
20150038596 | Differential Diagnosis Of Cancer And Other Conditions Based On Expression Of p63 - This invention relates to methods of distinguishing among various types of differentiated and undifferentiated epithelial carcinomas, and non-epithelial carcinomas, by detecting the presence of p63 nucleic acid or protein expression. The invention also provides methods for detecting p63 nucleic acids and proteins, as well as methods for diagnosing and treating certain tumors based on whether the tumors express p63. | 2015-02-05 |
20150038597 | WET SANDING COMPOSITIONS - A wet sanding adjuvant is comprised of a composition comprising: ( | 2015-02-05 |
20150038598 | SYSTEM, PROCESS AND REACTOR FOR CONDUCTING A SYNTHESIS GAS CONVERSION REACTION - A synthesis gas conversion process and system are disclosed. Fresh syngas from a methane reformer is used as a sweep zone gas feed which is caused to flow across a water permselective membrane in a membrane reactor. The water permselective membrane is adjacent a synthesis gas conversion reaction zone in which synthesis gas is contacted with a catalyst and converted to effluent including water. Water is removed from the reaction zone through the membrane and passes out of the reactor with the sweep zone gas. The water is then removed from the sweep zone gas forming a modified gas feed which is fed to the reaction zone. The modified gas feed has a preferred H | 2015-02-05 |
20150038599 | PROCESS FOR CO-PRODUCING COMMERCIALLY VALUABLE PRODUCTS FROM BYPRODUCTS OF HEAVY OIL AND BITUMEN UPGRADING PROCESS - The present invention is directed to modifications of bitumen and heavy oil upgrading and refining processes to synthesize synthetic crude oil and other valuable synthesized hydrocarbon products in an efficient manner along with the production of commercially valuable co-products from by-products formed by the upgrading process. | 2015-02-05 |
20150038600 | SYSTEM AND PROCESS FOR PRODUCING FUEL WITH A METHANE THERMOCHEMICAL CYCLE - A thermochemical process and system for producing fuel are provided. The thermochemical process includes reducing an oxygenated-hydrocarbon to form an alkane and using the alkane in a reforming reaction as a reducing agent for water, a reducing agent for carbon dioxide, or a combination thereof. Another thermochemical process includes reducing a metal oxide to form a reduced metal oxide, reducing an oxygenated-hydrocarbon with the reduced metal oxide to form an alkane, and using the alkane in a reforming reaction as a reducing agent for water, a reducing agent for carbon dioxide, or a combination thereof. The system includes a reformer configured to perform a thermochemical process. | 2015-02-05 |
20150038601 | CONSTANT VELOCITY UNIVERSAL JOINT - There is provided a constant velocity universal joint having excellent durability at high temperature while using a boot made of silicone rubber that does not include cerium oxide or other rare earth element-containing compound. The constant velocity universal joint is provided with an outer joint member ( | 2015-02-05 |
20150038602 | AMINE-OXIDE-GROUP-CONTAINING CONJUGATED POLYMER PHOTOELECTRIC MATERIAL AND USE THEREOF - Disclosed are an amine-oxide-group-containing conjugated polymer photoelectric material and application thereof. The amine-oxide-group-containing conjugated polymer photoelectric material consists of conjugated main chains and a side chain containing an amine oxide unit, and is applied in an organic photoelectric device. The material has desirable alcohol/water solubility and photoelectric properties, is suitable for making a multi-layer solution for machining a device, and meanwhile can prevent an adverse effect incurred by freely moving counter ions in a common polyelectrolyte to the device. The material may be used as a cathode interface modification layer applied in organic photoelectric devices such as light-emitting and photovoltaic devices, so as to improve performance of the devices. | 2015-02-05 |
20150038603 | BLOWING AGENT COMPOSITIONS OF HYDROCHLOROFLUOROOLEFINS - The present invention relates to foam products made with blowing agent compositions comprising at least one hydrochlorofluoroolefin (HCFO) used in the preparation of foamable thermoplastic compositions. The HCFOs of the present invention include, but are not limited to, 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd), particularly the trans-isomer, 2-chloro-3,3,3-trifluoropropene (HCFO-1233xf), dichloro-fluorinated propenes, and mixtures thereof. The blowing agent compositions of the present invention are used with coblowing agents including carbon dioxide, atmospheric gases, hydrofluorocarbons (HFC), hydrofluoroolefins (HFO), alkanes, hydrofluoroethers (HFE), and mixtures thereof. Preferred HFCs used as coblowing agents in the present invention include, but are not limited too, 1,1,1,2-tetrafluoroethane (HFC-134a), 1,1-difluoroethane (HFC-152a), 1,1,1-trifluoroethane (HFC-143a), pentafluorethane (HFC-125), difluoromethane (HFC-32). The blowing agent compositions are useful in the production of low density insulating foams with improved k-factor. | 2015-02-05 |
20150038604 | EXPANDABLE POLYURETHANE COMPOSITION AND MANUFACTURING METHOD OF FLEXIBLE POLYURETHANE FOAM - An expandable polyurethane composition includes (A) polyisocyanate, (B) active hydrogen containing compound including (B1) polyol and (B2) water, catalysts, and (C) cross-linking agent composition. The (C) cross-linking agent composition includes at least one kind of (C1) cross-linking agent selected from (CA) ethoxylate derivative having MW of 2000 or less and (CB) ester compound having MW of 2500 or less, and (C2) non-protic polar solvent, and a mass ratio ((a+b)/c) of a sum of content a of the (CA) ethoxylate derivative and content b of the (CB) ester compound relative to content c of the (C2) non-protic polar solvent is 1/10 to 10/1. A flexible polyurethane foam can be obtained of which wet set is improved and feeling is good. | 2015-02-05 |
20150038605 | LOW DENSITY FOAM, MIDSOLE, FOOTWEAR, AND METHODS FOR MAKING LOW DENSITY FOAM - Foamed thermoplastic elastomeric polyurethane and ethylene-vinyl acetate copolymer articles are made with a combination of a supercritical fluid and a non-supercritical fluid blowing agent. | 2015-02-05 |
20150038606 | LOW DENSITY FOAMED ARTICLES AND METHODS FOR MAKING - Foamed thermoplastic elastomeric polyurethane and ethylene-vinyl acetate copolymer articles are made with from about 0.1 to about 4 weight percent of supercritical fluid nitrogen based on polymer weight and from about 0.1 to about 5 weight percent of a supercritical fluid carbon dioxide based on polymer weight, with the supercritical fluid nitrogen and the supercritical fluid carbon dioxide being separately added to the molten polymer. | 2015-02-05 |
20150038607 | METHOD AND THERMOPLASTIC FOAMED ARTICLE - A method for making a low density foamed article includes placing a desired amount of thermoplastic polyurethane foam beads in a cavity of an injection mold and closing the mold; combining in an extruder connected to the mold a molten polymer selected from the group consisting of thermoplastic polyurethane elastomers and thermoplastic ethylene-vinyl acetate copolymers with both a physical or chemical blowing agent other than a supercritical fluid present in an amount up to about 15 wt % based on molten polymer weight and a supercritical fluid that is at least one of about 0.1 to about 5 weight percent of supercritical CO | 2015-02-05 |
20150038608 | MANUFACTURING METHOD OF POROUS POLYMER FILM USING VANADIUM OXIDE NANOWIRE, AND POROUS POLYMER FILM PREPARED THEREFROM - This patent is provided a method for producing a porous polymer film using vanadium oxide nanowires, and a porous polymer film obtained from the method. The method allows control of a uniform pore size and density through a simple process including the steps of: adding an ion exchanger to deionized water to perform acidification and adding a vanadate compound thereto to grow vanadium oxide nanowires by a sol-gel process; mixing the resultant solution of grown nanowires with a polymer solution to provide a mixed solution of nanowires; pouring the mixed solution of nanowires to a mold, followed by drying and curing, to form a film; and etching the resultant film with an etching solution to remove the vanadium oxide nanowires. | 2015-02-05 |
20150038609 | COMPOSITIONS FOR COMPOUNDING FOAMABLE, FLUROPOLYMER PELLETS FOR USE IN MELT PROCESSING CELLULAR OR FOAMED FLUOROPOLYMER APPLICATIONS - The disclosure provides a composition as well as a set of compositions and method for producing cellular or foamed or blown fluoropolymers such as perfluoropolymers and other thermoplastics articles allowing for the creation of a lower cost communications cable, conductor separator, conductor support-separator, jacketing, tape, wire insulation and in some cases a conduit tube as individual components or combined configurations that exhibit improved electrical, flammability and optical properties. Specifically, the foamable or blown fluoropolymer such as a perfluoropolymer cellular insulation composition comprises; talc and the selected fluoropolymer such as perfluoropolymers. Compounded pellets or products resulting in cellular or foamable products using these pellets has also been realized by providing the melt combination in the pellets of only talc and a perfluoropolymer. | 2015-02-05 |
20150038610 | RIGID FOAM AND ASSOCIATED ARTICLE - A polyurethane or polyisocyanurate foam is prepared from a reaction mixture that includes comprising a polyol, an aromatic isocyanate compound, and a blowing agent. The polyol includes a poly(phenylene ether) having a number average molecular weight of 600 to 2000 atomic mass units and an average of 1.5 to 3 hydroxyl groups per molecule. The polyurethane or polyisocyanurate foam exhibits improved resistance to burning and/or reduced elapsed times to formation of tack-free foams relative to foams prepared without the poly(phenylene ether). | 2015-02-05 |
20150038611 | Biodegradable nanocomposites containing nanoclay and titanium dioxide nanoparticles - In the present invention, biodegradable nanocomposites are introduced which include nanoclay particles, titanium dioxide nanoparticles, polyethylene, polypropylene, starch as a biopolymer, maleic anhydride and glycerol. The obtained nanocomposites have very high physical, mechanical and antimicrobial properties. Proper dispersion and distribution of nanoparticles in composite substrate would help in improving the quality of the product to a great extent. The presence of polypropylene next to polyethylene would eliminate the weak points of polyethylene/biopolymer composite as polypropylene helps to modify the physical and engineering properties of nanocomposites in the presence of nanoclay. Titanium dioxide nanoparticles have antimicrobial properties and would result in products which are useful for food and pharmaceutical industries. Another important aspect of this invention is the production of samples in one step by reaction extrusion method. | 2015-02-05 |
20150038612 | POLYMERS AND METHODS FOR OPHTHALMIC APPLICATIONS - Novel methods and materials particularly useful for ophthalmic applications and to methods for making and using the same are disclosed herein. More particularly, relatively soft, optically transparent, foldable, high refractive index materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and implanting IOLs made therefrom are disclosed. | 2015-02-05 |
20150038613 | Interpenetrating Networks With Covalent and Ionic Crosslinks - The invention features a composition comprising a self-healing interpenetrating network hydrogel comprising a first network and a second network. The first network comprises covalent crosslinks and the second network comprises ionic or physical crosslinks. For example, the first network comprises a polyacrylamide polymer and second network comprises an alginate polymer. | 2015-02-05 |
20150038614 | POWDER-LIQUID DENTAL CURABLE MATERIAL KIT - A powder-liquid dental curable material kit composed of (A) a liquid material and (B) a powder material, wherein the liquid material (A) contains (a1) a radically polymerizable (meth)acrylic monomer, (a2) an organic halogen compound and (a3) a radical chain transfer agent; the powder material (B) contains (b1) non-crosslinked resin particles, (b2) a pyrimidinetrione compound and (b3) an organic metal compound; and (Z) a peroxide is blended in at least one of the liquid material (A) and the powder material (B). This curable material kit is capable of reducing the heat generation during the curing of a curable material which is a mixture of the liquid material (A) and the powder material (B) and is not susceptible to the excessive prolongation of the curing time even when the curable material is cured by a brush-on technique, thereby ensuring an appropriate curing time for both of a brush-on technique and a kneading technique. | 2015-02-05 |
20150038615 | Polycarbonate and Method of Preparing the Same - A polycarbonate resin of the present invention is characterized by comprising repeating units represented by Formula 1, Formula 2, Formula 3 and Formula 4, respectively. | 2015-02-05 |
20150038616 | INK COMPOSITION FOR DECORATING NON-POROUS SUBSTRATES - The present invention relates to an ink composition for decorating non-porous substrates for printing on non-porous surfaces that are subjected to heat treatment after printing, and comprising at least one organic solvent as a vehicle which is liquid at room temperature and is made up of linear or non-linear n-alkane hydrocarbons, at least one binder composition with submicrometric particles of a glass frit, and at least one ceramic pigment corresponding to the color of the ink and to the etching of the ink. | 2015-02-05 |
20150038617 | METHOD FOR PREPARING A MASTERBATCH OF DIENE ELASTOMER AND SILICA - Preparation of a masterbatch of diene elastomer and silica including preparing at least one silica dispersion in water; bringing into contact and mixing an elastomer latex and the aqueous silica dispersion in the presence of a metal salt having an at least divalent metal element, in order to obtain a coagulum; and recovering the coagulum and drying same in order to obtain the masterbatch. The metal cation molar ration, defined as the number of moles of metal cations of the metal salt per BET unit area of the silica, is between 9.375*10 | 2015-02-05 |
20150038618 | FIBER FOR REINFORCING CEMENT, AND CURED CEMENT PRODUCED USING SAME - A cement reinforcing fiber of the present invention is a cement reinforcing fiber made of a polyolefin fiber, wherein a fiber treating agent is adhered to a surface of the polyolefin fiber, and the fiber treating agent is a polyoxyethylene alkyl phosphoric ester salt. One preferred polyoxyethylene alkyl phosphoric ester salt is a compound represented by chemical formula (2) below. A cured cement of the present invention contains the above-described cement reinforcing fiber. | 2015-02-05 |
20150038619 | Stiff Mycelium Bound Part and Method of Producing Stiff Mycelium Bound Parts - A self-supporting composite body comprising a substrate of discrete particles and a network of interconnected mycelia cells extending through and around the discrete particles and bonding the discrete particles together is characterized in being stiff and in having a density of greater than 18 pounds per cubic foot (pcf). The method of making the composite body includes compressing a mass of biocomposite material comprised of discrete particles and a network of interconnected mycelia cells in the presence of moisture into a compressed body having a density in excess of 18 pcf. Compression may take place batch wise. in a press or continuously between a pair of movable endless conveyors. | 2015-02-05 |
20150038620 | Solventborne Pigment Pastes Comprising Metallic Pigments And Use Thereof For Producing Solventborne Effect Coating Materials - Described are solventborne pigment pastes comprising lamellar effect pigments. Also described is the use of the solventborne pigment pastes comprising lamellar effect pigments for producing solventborne effect coating materials. Further described is a process for producing solventborne effect coating materials. | 2015-02-05 |
20150038621 | COMPOUND FOR REALIZATION OF MODIFIED BITUMEN FOR ASPHALTS - A production method of a compound for realization of modified bitumen for asphalts is disclosed, and includes the following steps: grinding of vulcanized rubber to obtain vulcanized crumb rubber with granulometry lower than 0.4 mm; mixing of the vulcanized crumb rubber, SBS and lubricant in an extruder, wherein the weight percentage of lubricant is between 1% and 50% compared to mixture weight and the vulcanized crumb rubber is in a weight percentage of 70-100% compared to SBS weight; in such way to obtain an extruded compound containing the vulcanized crumb rubber, SBS and lubricant. | 2015-02-05 |
20150038622 | STABILIZER AND COMPOSITION INCLUDING THE SAME - A stabilizer including a first component, a second component, and a third component is provided. The first component is a compound represented by formula (1), | 2015-02-05 |
20150038623 | COMPOSITIONS AND METHODS FOR IMPROVING FLUID-BARRIER PROPERTIES OF POLYMERS AND POLYMER PRODUCTS - In some variations, this disclosure provides compositions for reducing fluid permeability through a polymer membrane, the composition comprising a polymer (e.g., bromobutyl rubber) and mineral particles (e.g., kaolin particles) including fine particles with particle sizes between about 0.05 μm and about 1 μm and coarse particles with particle sizes between about 3 μm and about 20 μm. Applications for these improved-barrier polymers include tire innerliners, paint and paper coatings, films, adhesives, liners, paints, and hoses, for example. Methods of making and use these polymers are also disclosed. | 2015-02-05 |
20150038624 | Oxygen Tailoring of Polyethylene - Processes are disclosed for oxygen-tailoring polyethylene, particularly polyethylenes suitable for wire and cable applications. One process includes conveying a first polyethylene having a melt index ≦5.0 and an MWD ≦5.0 through mixing or extrusion apparatus having a feed zone, a melt-mixing zone downstream of the feed zone, and a melt zone downstream of the melt-mixing zone, wherein the temperature of the first polyethylene in the melt zone ranges from about 180° C. to about 300° C.; and contacting the first polyethylene with an amount of an oxygen-containing gas having at least about 20.0 parts by weight oxygen per million per parts by weight of the first polyethylene (ppm (wt) O | 2015-02-05 |
20150038625 | MONOBENZOATE USEFUL AS A PLASTICIZER IN ADHESIVE PREPARATIONS - A unique monobenzoate useful as a plasticizer in polymeric dispersions, such as adhesives, comprising 3-phenyl propyl benzoate, a monobenzoate ester used as a flavor and fragrance additive, but not heretofore utilized as a plasticizer for polymeric dispersions, such as adhesives, caulks and sealants. The inventive monobenzoate provides a suitable non-phthalate, lower VOC alternative plasticizer that is compatible with a wide variety of polymers. Advantages rendered by the use of the inventive monobenzoate include, among other things, excellent viscosity response, low viscosity, viscosity stability, improved rheology, good film formation and comparable or better adhesion, peel strength, set time, open time, chalk point and MFFT, compared with that achieved by traditional plasticizers. The inventive monobenzoate also has an excellent health, safety and environmental profile and provides a viable alternative for adhesives used in food contact applications, such as packaging, where migratory concerns are an issue. | 2015-02-05 |
20150038626 | STABILIZER COMPOSITIONS FOR THERMOPLASTIC POLYMERS - The present invention relates to a composition comprising a metal complex of a 1,3-diketone and an optionally substituted full ester of a monool or a diol and a monocarboxylic acid; wherein a mixture consisting of (a) and (b) has a viscosity of less or equal than 40 mPa·s when measured at 80° C. | 2015-02-05 |
20150038627 | Renewable Raw Material Based Coating Compositions - This disclosure relates to coating compositions that include a film-forming material and solvent. The coating compositions may contain from about 65% to 100%, by weight, renewable materials. The renewable material may be derived from renewable feedstock materials, including renewable biomass feedstock materials. | 2015-02-05 |
20150038628 | FREE-FLOWING SLURRIES OF SMALL PARTICLES OF AN ALKALI OR ALKALINE EARTH METAL BOROHYDRIDE - A method for dispersing an alkali or alkaline earth metal borohydride having median particle size less than 30 microns in an organic solvent. The method comprises combining the alkali or alkaline earth metal borohydride, the organic solvent and a surfactant. | 2015-02-05 |
20150038629 | POLYOLEFIN BASED FORMULATIONS FOR MEMBRANES AND FABRICS - The invention provides halogen-free, flame-retardant flexible polyolefin-based formulations. | 2015-02-05 |
20150038630 | STRUCTURAL ACRYLIC ADHESIVE - There is provided an adhesive composition comprising: a) at least one acrylic functional monomer; b) a first toughening agent; c) a second toughening agent; d) an adhesion promoter; and e) a high aspect ratio filler selected from at least one of a high aspect ratio fibrillated filler and a halloycite clay filler. | 2015-02-05 |
20150038631 | LIQUID CRYSTALLINE POLYESTER RESIN COMPOSITION - A liquid crystalline polyester resin composition has high strength and low warpage due to the reinforcement effects of a filler, high toughness to be resistant to pin press-fitting, good tribological property and good flexural fatigue characteristic. The liquid crystalline polyester resin composition includes 100 parts by weight of a liquid crystalline polyester (A) having a ratio (a)/[(a)+(b)] of an amount of terminal hydroxyl group (a) to a sum of the amount of terminal hydroxyl group (a) and an amount of terminal acetyl group (b) which is 0.70 to 1.00; and 10 to 100 parts by weight of a mica (B). The mica (B) included in the liquid crystalline polyester resin composition has a volume-average particle size of 10 to 50 μm. The mica (B) has an aspect ratio of 50 to 100. | 2015-02-05 |
20150038632 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION - The present invention provides curable compositions comprising non-tin metal catalysts that accelerate the condensation curing of moisture-curable silicones/non-silicones. In particular, the present composition employs a metal free catalyst system comprising a diazabicyclic compound as the catalyst. The diazabicyclic compounds exhibit catalytic activity comparable or superior to organotin such as DBTDL and exhibit certain behavior in the presence of components such as adhesion promoters that allow for tuning or adjusting the cure characteristics of the present compositions and provide good adhesion and storage stability. | 2015-02-05 |
20150038633 | RESIN COMPOSITION AND USE THEREOF - Disclosed is a resin composition comprising a melt-moldable side chain 1,2-diol-containing PVA-based resin (A), and fluororesin containing a polar functional group capable of reacting with or forming hydrogen bond(s) with hydroxyl group (B). The component (A) and the component (B) have excellent affinity, and therefore if either the component (A) or component (B) becomes matrix, the other can be finely dispersed into the matrix, thus providing a resin composition having excellent gas-barrier property, solvent resistance, and bending fatigue resistance. The present invention also provides emulsified dispersion and binder in which the resin composition is used. | 2015-02-05 |
20150038634 | IMPACT MODIFIED DENTURE BASE COMPOSITIONS - The present invention provides a composition including at least one polymerizable liquid component having at least one rubber impact modifier; at least one polymerization initiator, and at least one polymer component. | 2015-02-05 |
20150038635 | ANTI-SETTLING COMPOSITION AND METHODS FOR USE - An anti-settling additive, compositions containing anti-settling additives and methods for use, the additive containing a monomer or polymer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C | 2015-02-05 |
20150038636 | COMPOSITION, ELASTOMER BODY AND COUPLING - The invention relates to a composition, especially for an elastomer body of an elastic coupling, comprising the following components:—polyisoprene rubber having a proportion of 20 to 30% by weight,—butadiene rubber having a proportion of 20 to 30% by weight, based in each case on the total weight of the composition. The invention further relates to the use of the composition for production of an elastomer body, especially for an elastic coupling, preferably elastic shaft coupling. The invention additionally relates to an elastomer body, especially for an elastic coupling, which comprises the composition. The invention also relates to a coupling comprising the composition or the elastomer body. | 2015-02-05 |
20150038637 | High Filler Loaded Polymer Composition - This disclosure relates to a polymer composition comprising (A) a first polymer; (B) one or more fillers; and optionally (C) a cross-linking pack including cross-linking agents and coagents. The first polymer comprises at least one of (i) a propylene-based copolymer and (ii) an ethylene/C | 2015-02-05 |
20150038638 | FLEXIBLE WHITE REFLECTIVE DIELECTRIC FOR ELECTRONIC CIRCUITS - This invention is directed to a polymer thick film white reflective flexible dielectric composition comprising urethane resin, thermoplastic phenoxy resin, and white reflective powder. Dielectrics made from the composition can be used in various electronic applications to protect electrical elements and particularly to reflect light in 3D circuits containing LED's. | 2015-02-05 |
20150038639 | ONE POT BIOCATALYTIC PEROXIDE MEDIATED CURE - The present invention relates to a composition comprising a stable aqueous dispersion of crosslinkable polymer particles, a peroxidase enzyme, and a hydrophobic hydroperoxide having a 10-hour half life temperature of at least 100° C. The composition provides a robust one-pot peroxidase mediated cure for latex particles bearing a variety of polymerizable functional groups. | 2015-02-05 |
20150038640 | NOVEL POLYMER DISPERSANTS - The present invention relates to novel polymer dispersants and to a liquid compositions containing solid fine particles, such as organic or inorganic pigments and fillers, and the polymer dispersants. The polymer dispersants have at least one functional moiety of the formula I, which is bound to one of the termini or to the backbone of the polymer: (I) where # indicates the point of attachment to the terminus and/or to the polymer backbone; k is 0, 1, 2, 3 or 4, m is 0, 1, 2, 3, 4, 5, 6, 7, 8 or 9, A is a chemical bond or a divalent moiety selected from the group consisting of C | 2015-02-05 |
20150038641 | DISPERSING ADDITIVES BASED ON PHOSPHORIC ACID ESTER DERIVATIVES - The present invention relates to phosphoric acid derivatives, which are present as urea urethanes and contain a radical with an affinity for the binder in addition to at least one phosphoric acid ester group. Said phosphoric acid derivatives are especially suitable as wetting agents and dispersants. | 2015-02-05 |
20150038642 | OLEOPHOBIC COATINGS - A polymeric coating for a glass substrate includes a hexafluoropropylene oxide derived silane polymer. The hexafluoropropylene oxide derived silane polymer has a molecular weight of greater than about 5500, a thickness of between about 2 and about 15 nanometers and a coefficient of friction constant of less than about 0.35. A water contact angle of the polymeric hexafluoropropylene oxide derived silane coating decreases by less than about 27% after being subjected to 10000 abrasion cycles. | 2015-02-05 |
20150038643 | SILICON COMPOUND AND METHOD FOR PRODUCING SAME, AND USE THEREOF - A novel silicon compound capable of initiating radical polymerization is provided. The silicon compound is represented by the following general formula (1) | 2015-02-05 |
20150038644 | UREIDO-FUNCTIONALIZED AQUEOUS POLYMERIC DISPERSION - The present invention relates to a stable aqueous dispersion of acrylic based polymer particles with a first and a second polymeric domain, wherein the first polymeric domain is film-forming at room temperature and the second polymeric domain has a T | 2015-02-05 |
20150038645 | BIOMIMETIC ADHESIVE COMPOSITIONS COMPRISING A PHENOLIC POLYMER AND METHODS FOR USE THEREOF - Biomimetic adhesive compositions can be used in various aspects of subterranean treatment operations. Methods for treating a subterranean formation can comprise: providing an adhesive composition that comprises a first polymer comprising a plurality of monomers that comprise a phenolic moiety, a biopolymer that is crosslinkable with the first polymer, a crosslinking agent, and an oxidizing agent; introducing the adhesive composition into a subterranean formation; and forming a coacervate-bound surface in the subterranean formation by crosslinking the first polymer. | 2015-02-05 |
20150038646 | COMPOSITION FOR PRODUCING SHEET FOR FORMING LAMINATE, PROCESS FOR PRODUCING THE SAME, AND SHEET FOR FORMING LAMINATE - To provide a composition for producing a sheet for forming a laminate, which contains an ethylene-vinyl acetate copolymer and a polyethylene resin, by which the above-described problems in the width of the temperature range in which a processable viscosity range is obtained and the like are improved and which excels in processing properties such as a film-forming property when producing a sheet, and a sheet for forming a laminate using this. A composition for producing a sheet for forming a laminate, which contains an ethylene-vinyl acetate copolymer and polyethylene, wherein the composition has a sea-island structure in which the ethylene-vinyl acetate copolymer is a sea phase and the polyethylene is an island phase, and a sheet for forming a laminate using this. | 2015-02-05 |
20150038647 | TELECHELIC POLYOLEFIN AND PREPARATION THEREOF - Telechelic polyolefin of formula(I) and its derivatives: | 2015-02-05 |
20150038648 | Molecularly Imprinted Polymers Selective for Tobacco Specific Nitrosamines and Methods of Using Same - A class of molecularly imprinted polymers that specifically recognizes and binds to TSNAs are useful, for example, in analysis and separation of TSNAs from biological fluids. Such polymers are also useful in methods of treating and manufacturing tobacco products and materials. | 2015-02-05 |
20150038649 | BIO-INSPIRED METHOD OF OBTAIN MULTIFUNCTIONAL DYNAMIC NANOCOMPOSITES - A method for a polymeric or nanocomposite material. The method includes assembling a multiphase hard-soft structure, where the structure includes a hard micro- or nano-phase, and a soft micro- or nano-phase that includes a polymeric scaffold. In the method, the polymeric scaffold includes dynamically interacting motifs and has a glass transition temperature (T | 2015-02-05 |
20150038650 | CROSSLINKED NANOSTRUCTURED CAST SHEETS - Transparent and impact-resistant crosslinked acrylic composition consisting of a brittle matrix (I) having a glass transition temperature of greater than 0° C. and of elastomeric domains having a characteristic dimension of less than 100 nm consisting of macromolecular sequences (II) having a flexible nature with a glass transition temperature of less than 0° C. | 2015-02-05 |
20150038651 | Dinuclear Indium Catalysts and Their Use for (Co)Polymerization of Cyclic Esters - Provided are novel dinuclear indium catalysts of formula (A) that are capable of living and immortal ring opening polymerization and copolymerization of cyclic ester monomers for the preparation of biodegradable polymers and copolymers, in particular polyesters. Also disclosed are polymerization methods and polymer products. These dinuclear indium catalysts allow less costly, highly reactive living polymerization of cyclic ester monomers with possible high turn over rates and/or substantial stereo chemical and microstructure control. | 2015-02-05 |
20150038652 | BLENDS OF BIORENEWABLE POLYAMIDES AND METHODS OF MAKING THE SAME - The invention discloses a method to produce a blended polymer by mixing polyamide 11 and polyamide 6, 10. The method may be utilize melt mixing or may utilize blended solutions. The invention also includes a blended polymer, wherein the blended polymer is produced from polyamide 11 and polyamide 6,10. | 2015-02-05 |
20150038653 | TIN FREE POLYMER POLYOLS - Embodiments include polymer polyol dispersions which include a polyol liquid phase and solid particle phase. Embodiments include methods of making the polymer polyol dispersions. The polymer polyol dispersions are essentially free of tin, have a solid content of between about 20 and 50 wt % based on the total weight of the polymer polyol dispersion, and have a viscosity at 20C of less than 9000 mPas. The solid particle phase has more than 90% by weight of particles in the solid particle phase having a particle diameter of less than 5 μm. | 2015-02-05 |
20150038654 | EMULSIFIER FOR EMULSION POLYMERIZATION AND EMULSION POLYMERIZATION METHOD USING SAME - An emulsifier for emulsion polymerization includes a compound represented by the following general: | 2015-02-05 |
20150038655 | HIGH-PRESSURE RADICAL ETHYLENE CO-POLYMERIZATION PROCESS WITH A REDUCED TEMPERATURE OF THE REACTION MIXTURE PRIOR TO INTRODUCTION INTO THE REACTION ZONE - The present invention relates to a high-pressure radical ethylene polymerization process in which ethylene is polymerized with a polyunsaturated olefin comprising at least 6 carbon atoms and at least two non-conjugated double bonds of which at least one is terminal; and/or an alpha-omega-divinylsiloxane according to Formula (I) wherein R | 2015-02-05 |
20150038656 | Process for preparing polymers and reactor for performing the process - The invention relates to a process for preparing polymers from monomers and/or oligomers by adding a liquid comprising the monomers and/or oligomers dropwise to a continuous liquid phase in a reactor, the continuous liquid phase being immiscible with the liquid comprising the monomers and/or oligomers, and the monomers and/or oligomers reacting in the continuous liquid phase to give the polymer. The liquid comprising the monomers and/or oligomers is shaped to droplets outside the continuous liquid phase, which are subsequently introduced into the continuous liquid phase. The invention further relates to a reactor for performing the process, comprising a tube through which a continuous liquid phase flows, and means of generating droplets, the means of generating droplets being arranged such that the droplets are generated outside the continuous liquid phase and then introduced into the continuous liquid phase. | 2015-02-05 |
20150038657 | PREPARATION PROCESS OF BRANCHED CONJUGATED DIENE POLYMER - There is provided a process for preparing a branched conjugated diene polymer by copolymerizing 1 to 100% by weight of a branched conjugated diene compound (1) monomer: | 2015-02-05 |
20150038658 | METHOD FOR PRODUCING (METH)ACRYLATE COPOLYMER - [Object] To produce a (meth)acrylate copolymer useful as a photocurable resin composition at a temperature favorable to industrial production in a short time. | 2015-02-05 |
20150038659 | PROCESS FOR PREPARING HALOGENATED POLYMERS - The invention concerns a process for the aqueous suspension, micro-suspension, emulsion or micro-emulsion polymerization of at least one halogenated monomer, in particular chlorinated, for example vinyl chloride, by itself or with one or more other vinyl monomers, preferably less than 50% by weight of one or more other vinyl monomers, in which at least one shortstopper and at least one perhalogenate, acting as a whitening agent, are added. | 2015-02-05 |
20150038660 | CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS - The present invention relates to a catalyst component for polymerization of an olefin comprising a compound represented by the Fischer projection of: wherein R | 2015-02-05 |
20150038661 | WATERSOLUBLE LINEAR COPOLYMER - The invention concerns the water-soluble linear heterochain dipolymer having the general formula: | 2015-02-05 |
20150038662 | ALKYLENE OXIDE-MODIFIED DIPENTAERYTHRITOL (METH)ACRYLATE AND REACTIVE COMPOSITION CONTAINING SAME - An alkylene oxide-modified polyfunctional (meth)acrylate is provided wherein the problems according to high crystallinity or high viscosity are improved, and the photosensitivity, etc. is enhanced. The compound has a structure represented by the following formula (I), provided that in the formula (I), R represents a substituent represented by the formula (II); AO represents one member or two or more members selected from alkylene oxide units represented by —CH | 2015-02-05 |
20150038663 | MULTISTAGE DRAWING PROCESS FOR DRAWING POLYMERIC ELONGATED OBJECTS - The invention relates to a multistage drawing process for the drawing of polymeric elongated objects, containing a first drawing stage and a final drawing stage and optionally containing at least one intermediate drawing stage subsequent to the first drawing stage and prior to the final drawing stage, comprising in the following order the steps of: a. providing a polymeric elongated feed object; b. drawing the elongated object in the first drawing stage with a draw ratio of between 30% and 90% of the maximum drawing ratio achievable in the first drawing step; c. optionally drawing the elongated object in the at least one intermediate drawing stage with a draw ratio of between 30% and 90% of the maximum drawing ratio achievable in the at least one intermediate drawing step; d. drawing the elongated object in the final drawing stage with a draw ratio of at most 5, preferably of at most 3. | 2015-02-05 |
20150038664 | METHOD FOR PRODUCING POLYETHER - To provide a method for producing a polyether having a weight average molecular weight of from 15,000 to 550,000. | 2015-02-05 |
20150038665 | PRODUCTION OF POLYOLS USING DISTILLERS GRAINS AND PROTEINS AND LIGNIN EXTRACTED FROM DISTILLERS GRAINS - Processes for the production of polyols from sources such as dried distillers grains plus solubles (DDGS) make use of a two-stage reaction scheme. In the first stage, the proteinaceous starting material is reacted with an aminating agent, such as diethanolamine (DEOA), to generate amino-amides and amides. These products are then reacted with an alkoxylating agent, preferably a substituted or unsubstituted epoxide to yield polyols. These polyols may be further reacted with isocyanates to give low-cost rigid polyurethane foams. In alternate forms, lignin may be directly converted to polyols by reaction with an alkoxylating agent, optionally followed by reaction with an isocyanate to produce polyurethanes. | 2015-02-05 |
20150038666 | Photoelectric Conversion Material, Method For Producing The Same, And Organic Photovoltaic Cell Containing The Same - A bulk heterojunction-type organic photovoltaic cell, i.e., BHJ solar cell, has a photoelectric conversion layer containing a mixture of a donor domain and an acceptor domain. The donor domain contains a polymer as a donor (photoelectric conversion material), and the polymer is obtained by reaction of a polyphenylene having a structural unit selected from moieties represented by the following general formulae (1) to (3). For example, the acceptor domain contains phenyl-C | 2015-02-05 |
20150038667 | POLY(PHENYLENE ETHER) COPOLYMER AND METHOD OF MAKING - A poly(phenylene ether) copolymer comprising about 5 to 40 mole percent repeat units derived from 2-phenylphenol and 60 to about 95 mole percent repeat units derived from 2,6-dimethylphenol, wherein the poly(phenylene ether) copolymer has a weight average molecular weight of at least 8,000 atomic mass units, is disclosed. Also disclosed is a method of preparing the poly(phenylene ether) copolymer, the method comprising oxidatively copolymerizing a monomer mixture comprising about 5 to 40 mole percent 2-phenylphenol and about 60 to about 95 mole percent 2,6-dimethylphenol in the presence of a solvent, molecular oxygen, and a polymerization catalyst comprising a metal ion and at least one amine ligand to form a solution of the poly(phenylene ether) copolymer in the solvent, wherein a ratio of total moles of 2-phenylphenol and 2,6-dimethylphenol to moles of metal ion is about 10:1 to about 1200:1. | 2015-02-05 |
20150038668 | Branched Polyesters Based On Citric Acid, Their Preparation And Use - Branched polyesters obtained by polycondensation of citric acid with at least one poly-alcohol having at least two hydroxyl groups and, if desired, further polycarboxylic acid components, the molar ratio of citric acid to polyalcohol being 2.4:1 to 1:3. | 2015-02-05 |
20150038669 | Process to Produce Polycarbamate Using a Gradient Feed of Urea - A process to produce polycarbamate comprising providing urea in liquid form; and adding the urea in liquid form to a polyol in a reduced gradient profile to form polycarbamate product is provided. Also provided are: (a) a reaction product of the process and (b) an apparatus for operating the process. | 2015-02-05 |
20150038670 | Process for Preparing Polycarbamate and Reaction Product Thereof - A first process to produce polycarbamate comprising providing urea in liquid form; and adding the liquid urea to a polyol is provided. A second process for producing polycarbamate comprising adding solid urea to a polyol in liquid form to form a reaction mixture is provided. Also provided is a reaction product produced by the first process or second process. | 2015-02-05 |
20150038671 | Efficient Synthesis of CN2097 and RC7 and Their Analogs - Synthesized macrocyclic ligand, CN2097 and analogs, optimized with systemic structure modifications to develop the compounds with lower molecular weights and less peptidic characters. | 2015-02-05 |
20150038672 | Modular Imaging Agents Containing Amino Acids and Peptides - Targeting agents are derived from coupling together formed imaging amino acids or formed multi-modal, multi-chelating metal, multi-dye imaging agents, or combinations of these, that may be conjugated directly, or activated, or attached to linkers to which targeting groups, such as peptides, proteins, antibodies, aptamers, or small molecule inhibitors, may be conjugated in the final steps of the synthesis to form a wide variety of TMIAs. | 2015-02-05 |
20150038673 | MUTANT DOUBLE CYCLIZED RECEPTOR PEPTIDES INHIBITING BETA1-ADRENOCEPTOR ANTIBODIES - The present invention relates to novel β-AR homologous cyclopeptide-mutants comprising only two cysteine residues able to form an intramolecular linkage, to linear peptides that can form these cyclopeptide-mutants and to nucleic acid molecules encoding these cyclopeptide-mutants and linear peptides. Moreover, vectors and recombinant host cells comprising said nucleic acid molecule and a method for producing the disclosed cyclopeptide-mutants are provided. Further provided is a composition comprising the peptides, nucleic acid molecules, vectors or host cells of the invention. The present invention also relates to therapeutic and diagnostic means, methods and uses taking advantage of the peptides of the invention and to means, methods and uses for detecting anti-.beta.-adrenergic receptor antibodies like anti-β | 2015-02-05 |
20150038674 | USE OF GLP-2 ANALOGUES IN PULMONARY DISEASES FOR THERAPEUTIC PURPOSE - The present invention relates to the use of GLP-2 analogue in an efficient amount for the production of a drug specific to treat a pulmonary disease which IS caused by oxidative stress, inflammation and/or apoptosis in an organism. | 2015-02-05 |
20150038675 | PEPTIDE HAVING AFFINITY FOR SILICON NITRIDE (SI3N4), AND USE THEREOF - The purpose of the present invention is to provide: a peptide having an affinity for silicon nitride; a polynucleotide encoding the peptide; an expression vector for expressing the peptide having an affinity for silicon nitride; an expression vector for expressing a peptide fusion protein that comprises the peptide having an affinity for silicon nitride and a target protein; a transformant obtained by introducing the expression vector into a host cell; a peptide fusion protein obtained from the transformant; a silicon nitride substrate to which a peptide having an affinity for silicon nitride has been bonded; a method for immobilizing a target protein to a silicon nitride substrate; a composition for immobilizing a target protein to a silicon nitride substrate, the composition comprising a peptide having an affinity for silicon nitride; and a linker for immobilizing a target protein to a silicon nitride substrate, the linker comprising a peptide having an affinity for silicon nitride. The invention involves a peptide having an affinity for silicon nitride, the peptide comprising (1-1) a peptide having the amino acid sequence of one of SEQ ID NOS: 1, 2 and 23 to 27, (1-2) a peptide that has an affinity for silicon nitride and comprises an amino acid sequence obtained by deleting, adding, and/or substituting one or more amino acids in one of the amino acid sequences indicated in (1-1), or a fragment of one of the peptides. | 2015-02-05 |
20150038676 | Biologically Active Peptides - A peptide or peptide derivative comprising:
| 2015-02-05 |
20150038677 | PROCESS FOR THE SYNTHESIS OF TELAPREVIR, OR PHARMACEUTICALLY ACCEPTABLE SALTS OR SOLVATES AS WELL AS INTERMEDIATE PRODUCTS THEREOF - The invention relates to a process for the preparation of telaprevir, or a pharmaceutically acceptable salt or solvate thereof, wherein the process requires a smaller number of process steps and/or does not require the use of toxic and instable compounds compared to the known processes. Another embodiment refers to telaprevir, or a pharmaceutically acceptable salt or solvate thereof as well as to intermediate products for preparation of the same, wherein the afore-mentioned products are obtained by the process described herein. | 2015-02-05 |
20150038678 | Interleukin-10 Polypeptide Conjugates and Their Uses - This invention relates to interleukin-10 (IL-10) polypeptide conjugates comprising at least one non-naturally-encoded amino acid. | 2015-02-05 |
20150038679 | Interleukin-3 Polypeptide Conjugates and Their Uses - The disclosure provides methods for targeting interleukin-3 receptor-expressing cells, particularly inhibiting the growth of such cells by using an interleukin-3 (IL-3) variant conjugated to a toxin that will affect cells expressing the interleukin-3 receptor. Further disclosed are interleukin-3 (IL-3) variants comprising one or more non-naturally encoded amino acids, and the structures of non-naturally encoded amino acids. | 2015-02-05 |
20150038680 | SPIDER SILK DRAGLINE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USE THEREOF - The disclosure provides spider silk polypeptides and polynucleotides encoding the same. Methods of using such polypeptides and polynucleotides and designing novel biomaterials using repeat units of the polypeptides and polynucleotides. | 2015-02-05 |
20150038681 | METHOD OF PREPARING A PRODUCT BY DIALYSIS - A method of preparing a product, preferably in the form of a functionalized high molecular weight component such as, for example, a functionalized protein includes passing a first liquid comprising a component A along one side of a semi-permeable membrane and passing a second liquid comprising a component B along another, preferably opposing, side of the membrane, wherein the membrane excludes passage of component A but allows passage of component B, and after passage of component B through the membrane, a chemical reaction takes place between component A and component B, preferably with the formation of covalent bonds. | 2015-02-05 |
20150038682 | ANTIBODIES OR FUSION PROTEINS MULTIMERIZED VIA HOMOMULTIMERIZING PEPTIDE - The invention provides antibodies or fusion proteins with modified heavy chain IgG constant regions that promote assembly of multimeric complexes. Within an antibody or fusion protein unit there are two heavy chains each including at least CH2 and CH3 regions. The two heavy chains bear complementary modifications (e.g., knob and hole) to promote coupling of the heavy chains within a unit. One and only one of the heavy chains in a unit is fused at its C-terminus to a homomultimerizing peptide. The presence of the homomultimerizing peptide promotes association between units. For example, if the homomultimerizing peptide is a homotrimerizing peptide it promotes association of three units to form a trimeric complex. | 2015-02-05 |
20150038683 | METHODS AND COMPOSITIONS FOR THE GENERATION AND USE OF CONFORMATION-SPECIFIC ANTIBODIES - The present invention features methods and compositions for the generation and use of conformation-specific antibodies or fragments thereof. | 2015-02-05 |
20150038684 | BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF - The invention is directed to a bispecific chimeric antigen receptor, comprising: (a) at least two antigen-specific targeting regions; (b) an extracellular spacer domain; (c) a transmembrane domain; (d) at least one co-stimulatory domain; and (e) an intracellular signaling domain, wherein each antigen-specific targeting region comprises an antigen-specific single chain Fv (scFv) fragment, and binds a different antigen, and wherein the bispecific chimeric antigen receptor is co-expressed with a therapeutic control. The invention also provides methods and uses of the bispecific chimeric antigen receptors. | 2015-02-05 |
20150038685 | MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITION - An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of | 2015-02-05 |
20150038686 | Polymeric Carriers of Therapeutic Agents and Recognition Moieties for Antibody-Based Targeting of Disease Sites - The present invention concerns methods and compositions for delivery of therapeutic agents to target cells, tissues or organisms. In preferred embodiments, the therapeutic agents are delivered in the form of therapeutic-loaded polymers that may comprise many copies of one or more therapeutic agents. In more preferred embodiments, the polymer may be conjugated to a peptide moiety that contains one or more haptens, such as HSG. The agent-polymer-peptide complex may be delivered to target cells by, for example, a pre-targeting technique utilizing bispecific or multispecific antibodies or fragments, having at least one binding arm that recognizes the hapten and at least a second binding arm that binds specifically to a disease or pathogen associated antigen, such as a tumor associated antigen. Methods for synthesizing and using such therapeutic-loaded polymers and their conjugates are provided. | 2015-02-05 |
20150038687 | METHOD FOR THE PREPARATION OF DIAZOALKANES - The present invention relates to a method of forming diazoalkanes. One aspect of the present invention provides a method for the production of a N-alkyl-N-nitroso compound from a starting material, comprising the use of a tribasic acid to acidify an amine. A second aspect of the present invention provides a method for the production of a diazoalkane, comprising reacting a N-alkyl-N-nitroso compound with a base and a phase transfer catalyst, wherein no organic solvent is used. | 2015-02-05 |
20150038688 | USE OF METALLOPORPHYRINS AND SALEN COMPLEXES FOR THE CATALYTIC OXIDATION OF ORGANIC COMPOUNDS - A method of decomposing an organic substrate includes identifying an organic substrate or its constituents having one or more desired or undesired properties; and contacting the organic substrate with an oxidizing agent and a catalyst selected from the group consisting of sterically hindered and electronically activated metallotetraphenylporphyrins, metallophthalocyanines and metallosalen complexes in an aqueous or aqueous-organic solution to produce a treated composition comprising one or more degradation products, wherein the degradation products have one or more desired properties and/or lack the undesired properties of the organic substrate. | 2015-02-05 |
20150038689 | Reagent-Controlled Stereoselective Glycosylation - Provided are methods for the efficient stereoselective formation of glycosidic bonds, without recourse to prosthetic or directing groups. | 2015-02-05 |
20150038690 | GELATIN-BASED NANOPARTICLE COMPLEX FOR TUMOR-TARGETED DELIVERY OF siRNA AND METHOD FOR PREPARING THE SAME - Disclosed is a gelatin-based nanoparticle complex for tumor-targeted delivery of siRNA for specific gene silencing in tumor cells. The gelatin-based nanoparticle complex includes: poly-siRNA chains whose ends are modified with thiol groups; and thiolated gelatin bound to the poly-siRNA chains through disulfide crosslinking and charge interactions. The gelatin-based nanoparticle complex is not degraded in the bloodstream and can be efficiently absorbed into tumor cells without cytotoxicity. The delivered siRNA can effectively silence target gene expression. Also disclosed is a method for preparing the gelatin-based nanoparticle complex. | 2015-02-05 |
20150038691 | POLYNUCLEOTIDE CONFIGURATION FOR RELIABLE ELECTRICAL AND OPTICAL SENSING - A mixed polynucleotide includes a first double stranded (ds) portion, a second portion including at least one single stranded (ss) portion, and a third ds portion. The second portion connects the first ds portion and the third ds portion to provide a modified polynucleotide. | 2015-02-05 |
20150038692 | SYNTHESIS OF PROTECTED 3'-AMINO NUCLEOSIDE MONOMERS - Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base. | 2015-02-05 |