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06th week of 2015 patent applcation highlights part 49
Patent application numberTitlePublished
20150038292CONTROL DEVICE FOR VEHICLE DRIVE DEVICE - A control device of a vehicle drive device includes an engine having a supercharger and an automatic transmission outputting power of the engine to drive wheels, when a supercharging pressure at the end of the upshift is increased as compared to the start of the upshift such that an engine torque at an end of an upshift of the automatic transmission is made larger than that at a start of the upshift, a target supercharging pressure being set depending on a predicted engine operation state after the upshift to allow a shift operation to proceed while an increase of the supercharging pressure is started before a completion of the upshift such that the supercharging Pressure reaches the target supercharging pressure, the supercharging pressure being controlled such that a target engine torque determined based on a vehicle state is achieved, and when the supercharging pressure cannot be increased in the upshift before the end of the upshift to a magnitude required for generating the target engine torque at the end of the upshift, a predefined engine torque lower than the target engine torque at the end of the upshift being retained after the end of the upshift.2015-02-05
20150038293DUAL CLUTCH POWERTRAIN ARCHITECTURE - A powertrain architecture includes an engine and a transmission coupled through a launch device that is configured to be selectively mechanically coupled to the engine and to the transmission. A ring gear is positioned at least partially around the launch device. An engine lock up clutch mechanically couples the engine to the ring gear. A turbine lock up clutch mechanically couples the launch device to the ring gear. Ancillary devices are provided to receive power from or transmit power to the ring gear. The engine lock up clutch and the turbine lock up clutch selectively engage the ring gear to power at least one ancillary device.2015-02-05
20150038294METHOD FOR CONTROLLING A TRANSMISSION COUPLED TO AN ENGINE THAT MAY BE AUTOMATICALLY STOPPED - Methods and systems for controlling a transmission coupled to an engine during an engine start are presented. In one example, a method adjusts a transmission tie-up force in response to an indication of transmission slip. The method may improve vehicle launch for stop/start vehicles.2015-02-05
20150038295POWER TRANSMISSION APPARATUS - A power transmission apparatus comprises an input shaft, an output shaft, a clutch device, and an actuator. The clutch device comprises a clutch hub, a clutch housing, a clutch pack, an input side cam mechanism for pressing the clutch pack toward the output shaft, an output side cam mechanism for pressing the clutch pack toward the input shaft, a return spring for urging the clutch pack to have its elements moved away from each other, and a drive shaft having an input side gear for transmitting the driving force of the actuator to the input side cam mechanism, and an output side gear for transmitting the driving force of the actuator to the output side cam mechanism.2015-02-05
20150038296SHIFT CONTROL SYSTEM FOR ELECTRIC VEHICLE - A shift control device for an electric vehicle that is arranged to perform a downshift by a combination of a disengagement of a frictional element and an engagement of an engagement element, and a shift control means configured to perform a shift control of the automatic transmission, the shift control device includes: a regenerative cooperative brake control means which is configured to perform a regenerative cooperative brake control by a switching to increase a frictional torque of a frictional brake device provided to the driving wheel to follow a decrease of a regenerative torque when the regenerative torque by the electric vehicle is decreased, the shift control means setting a timing of a start of a coast downshift to disengage the frictional element, at least to a timing after a timing at which the switching of the regenerative cooperative brake control is started.2015-02-05
20150038297POWER GENERATING MANUALLY OPERATED TREADMILL - The present invention relates to a manually operated treadmill adapted to generate electrical power comprising a treadmill frame, a running belt supported upon the treadmill frame and adapted for manual rotation, and an electrical power generator mechanically interconnected to the running belt and adapted to convert the manual rotational motion of the running belt into electrical power.2015-02-05
20150038298HEAD AND NECK EXERCISE APPARATUSES - A head and neck exercise apparatus may include a member operatively arranged with a valve mechanism with a threshold pressure. The apparatus may further include an acoustic apparatus, membrane, chromogenic material, or moveable element that may be configured to respond when the pressure within the member is greater in magnitude than the threshold pressure. The head and neck exercise apparatus may also include a member operatively arranged with an acoustic apparatus, membrane, chromogenic material, or moveable element that may be configured, without a valve mechanism, to respond when the absolute pressure within the member is greater in magnitude than a threshold absolute pressure.2015-02-05
20150038299HEAD AND NECK EXERCISE METHODS - Methods for instructing a user to perform head and neck exercises with head and neck apparatuses are disclosed. The apparatus may include a member operatively arranged with a valve mechanism with a threshold pressure. The apparatus may further include an acoustic apparatus, membrane, chromogenic material, or moveable element that may be configured to respond when the pressure within the member is greater in magnitude than the threshold pressure. The head and neck exercise apparatus may also include a member operatively arranged with an acoustic apparatus, membrane, chromogenic material, or moveable element that may be configured, without a valve mechanism, to respond when the absolute pressure within the member is greater in magnitude than a threshold absolute pressure.2015-02-05
20150038300UNIVERSAL FITNESS APPARATUS - An exercise apparatus having: a frame having a vertical support; at least one articulating arm mount affixed to the vertical support; a first articulating arm connected to the at least one articulating arm mount; a second articulating arm connected to the at least one articulating arm mount, the second articulating arm adapted to independently articulate from the first articulating arm; a pair of resistive elements, each resistive element operatively connected to one of the first and second independently articulating arms to provide resistance; and a cable and pulley system connecting each resistive element to a point on a longitudinal axis of one of the first and second articulating arms.2015-02-05
20150038301Core Exercise Apparatus and Methods - A dual-mode exercise apparatus may include an articulating arm assembly coupled through a joint to a support assembly. In an illustrative embodiment, the arm assembly may include a seat centrally mounted above a ball-and-socket joint and a stabilizer member for the hands and/or feet of the user. In a first mode of operation a user sits on the seat and uses his or her core muscles to articulate the seat on the ball-and-socket joint against the resistance provided by, for instance, weights mounted on distal portions of the arm assembly. In certain embodiments the apparatus may further provide a second mode of operation which simulates rowing a kayak. In a corresponding illustrative embodiment a user sits in a second seat positioned rearward of the arm assembly and the arm assembly includes handle members. In operation the user articulates the handles in a manner akin to rowing a kayak.2015-02-05
20150038302Weightlifting Barbell - A weightlifting barbell includes a steel shaft and sleeves constructed of engineered plastic (e.g., POM, Teflon®, Nylon, UHMW, and the like). The engineered-plastic sleeve is relatively light weight and provides impact strength suitable for executing weightlifting exercises.2015-02-05
20150038303Kinetic Dumbbell - A kinetic dumbbell includes offset weighted ends keyed to a single axle and a grip residing over the axle and between the weighted ends. The axle and weighted ends are free to rotate with respect to the grip. The weighted ends include slots accepting weights to adjust an offset weight of each weighted end. A timer/counter may be attached to one end to signal a user that an exercise is completed. The axle is attached to the weighted ends using a key through the axle, the key residing in channels in the weighted ends to rotationally fixing the axle to each weighted end, and screws and washers to hold the weighted ends on the axle. Bushings reside over the axle and engage each end of the handle to position the handle on the axle.2015-02-05
20150038304MULTI-PURPOSE EXERCISE BENCH WITH VERSATILE RESISTANCE ACCESSORY - A multi-purpose exercise bench having a versatile resistance accessory configurable for use to provide weight-training resistance in a variety of exercises is provided. A multi-purpose exercise bench comprises: an elongated frame configured to rest on a flat floor in a stable manner; a lower seat portion supported on the frame; a resistance accessory mounted to the frame, the resistance accessory comprising: a pad movably mounted to the frame to be movable between a first position and a second position; a locking mechanism operable to lock the pad in either of the first position and the second position; and a plurality of resistance bands attached to the pad. A multi-purpose exercise system include the multi-purpose exercise bench and an exercise bar defining at least one groove dimension to receive at least one receiver ring attached to at least one of the resistance bands.2015-02-05
20150038305SURFBOARD REPLICATING BALANCE BOARD SYSTEM - A balance board adapted for riding rail-to-rail, preferably so that at least a portion of a rider's feet will be placed on the board over the elongated roller. The balance board includes an elongated, planar board having a length that exceeds a width. The balance board further includes two pair of stops mounted to an underside of the board, each pair of stops being mounted near opposite ends of the board, and each stop of the pair of stops being mounted near opposite sides of the board. The balance board further includes a traction region between each stop of each pair of stop.2015-02-05
20150038306APPARATUS FOR CHANGING WELDING TIP - An apparatus for interchanging welding tips of a spot welding gun. The apparatus replaces a welding tip installed in a robot arm and includes welding tip removal componentry combined with the robot arm, welding tip mounting means combined with one side of the welding tip removal componentry, and a welding tip supply spaced apart from the welding gun at a specific distance and configured to supply a welding tip to the welding tip mounting componentry.2015-02-05
20150038307AUTOMATIC TOOL STORING MECHANISM - An automatic tool storing mechanism has a plurality of main magazine, transporting means, and a tool exchanging arm. Each main magazine holds a large number of pots with tools. The transporting means transports the pots with tools one by one between the main magazine and the waiting position close to the main spindle. The tool exchanging arm takes out an unused or preused pot with tool which is waiting at the waiting position and attaches it to the main spindle and also removes the used tool from the main spindle and places it in the pot.2015-02-05
20150038308Adjustable Roller Frame - An adjustable roller frame may include a frame, a pair of extension arms that are slidable within a channel in the frame, and a pair of cam assemblies that are used to selectively prevent and permit the extension arms to slide.2015-02-05
20150038309Method For Lubricating Pressure Relief Valves - A method for applying a lubricant to a pressure relief valve during the process of applying the pressure relief valve to packaging. The method includes temporarily separating layers of the valve with a vacuum applicator when the lubricant is applied. A pressurized nozzle sprays or atomizes the lubricant into the valve opening. Graphite suspended in liquid silicone is used as the lubricant; it is recirculated in a reservoir to keep the graphite in suspension. Optical sensors check for valves before the entrance to, and after exit from, the vacuum applicator.2015-02-05
20150038310Oil Centrifuge with Centrifuge Rotor - An oil centrifuge has an integral, rotatably mounted centrifuge rotor and a feed tube connected to the centrifuge rotor. A flow path is provided that supplies oil to the centrifuge rotor. The feed tube is a section of the flow path. The flow path has a throttle point having a reduced throttle cross section that is reduced relative to an upstream flow path cross section of the flow path upstream of the throttle point.2015-02-05
20150038311CENTRIFUGE EQUIPPED WITH A BALANCING MECHANISM AND METHOD OF BALANCING SUCH A CENTRIFUGE - The disclosure relates to a centrifuge with a balancing mechanism and method of balancing such a centrifuge. The centrifuge includes a vertical shaft driven in rotation by a motor, and a mechanism for balancing the parts integral with said vertical shaft. The mechanism includes a plate integral with the vertical shaft, at least one compensating mass freely displacing on the plate, the mass being designed to limit the imbalance of parts integral with the vertical shaft, and a mechanism for blocking the compensating mass, the blocking mechanism being designed to immobilize the compensating mass on the plate when the rotation speed exceeds a determined value.2015-02-05
20150038312COMPOSITION FOR PRODUCING GLASS SOLDERS FOR HIGH-TEMPERATURE APPLICATIONS AND USE THEREOF - The invention relates to compositions for the manufacture of glass solders for high-temperature applications up to temperatures of approx. 1000° C. and to their use. SiO2 having a proportion in the range from 48 mol-% to 62 mol %, Al2O3 having a proportion in the range from 0.5 mol % to 6 mol %, B2O3 having a proportion in the range 4 mol % to 12 mol % and BaO having a proportion in the range 12 mol % to 30 mol % as well as CaO having a proportion in the range from 2.5 mol % to 15 mol %, or an R2O3 having a proportion in the range 0.5 mol % to 20 mol % are contained in the composition in accordance with the invention, where the R2O3 is selected from La2O3, Y2O3, Sc2O3 and from a further oxide of a chemical element from the series of lanthanoids. In this respect, an SiO2:BaO ratio in the range from 1.9 to 4 is observed and no ZrO2 is contained.2015-02-05
20150038313METHOD AND APPARATUS FOR PERFORMING LASER FILAMENTATION WITHIN TRANSPARENT MATERIALS - Systems and methods are described for forming continuous laser filaments in transparent materials. A burst of ultrafast laser pulses is focused such that a beam waist is formed external to the material being processed without forming an external plasma channel, while a sufficient energy density is formed within an extended region within the material to support the formation of a continuous filament, without causing optical breakdown within the material. Filaments formed according to this method may exhibit lengths exceeding 10 mm. In some embodiments, an aberrated optical focusing element is employed to produce an external beam waist while producing distributed focusing of the incident beam within the material. Various systems are described that facilitate the formation of filament arrays within transparent substrates for cleaving/singulation and/or marking. Optical monitoring of the filaments may be employed to provide feedback to facilitate active control of the process.2015-02-05
20150038314CHALCOGENIDE GLASS - Boron-containing network sulfide glass which may be useful in IR transmitting applications, such as IR optics, laser or fiber amplifiers doped with rare earths with emission in the near IR, and methods of making the same.2015-02-05
20150038315METHOD FOR PRODUCING CHEMICALLY TEMPERED GLASS - To provide a method for producing chemically tempered glass, whereby frequency of replacement of the molten salt can be reduced. A method for producing chemically tempered glass, which comprises repeating ion exchange treatment of immersing glass in a molten salt, wherein the glass comprises, as represented by mole percentage, from 61 to 77% of SiO2015-02-05
20150038316GLASS PLATE - To provide a glass plate which can be made to have higher Te than conventional glass plates when its iron content is substantially the same as the conventional glass plates, to have substantially the same level of Te as conventional glass plates when its iron content is larger than the conventional glass plates, or to have very high Te when its iron content is smaller than conventional glass plates, and which presents good productivity. A glass plate which comprises, as represented by mol percentage based on oxides, SiO2015-02-05
20150038317Direct Smelting Process - A molten bath-based direct smilting process comprises controlling the process conditions in a direct smelting vessel so that molten slag in a molten bath of metal and slag in the vessel has a viscosity in a range of 0.5-5 poise when the slag temperature is in the range of 1400-1550° C. in the molten bath in the vessel.2015-02-05
20150038318Building Brick Comprising A Porous Material, The Microstructure Of Which Is Controlled By The Addition Of A Nucleating Agent During The Process Of Preparing Same - A building brick with cellular structure comprising a porous material, said porous material being obtained by a process comprising the following successive steps: 2015-02-05
20150038319MEDICAL CERAMIC MATERIAL AND MANUFACTURING METHOD THEREOF - The present invention provides a medical ceramic material with a color other than black or white, especially blue, with which it is possible to secure sufficient durability and to maintain a good appearance by sufficiently suppressing a color difference between before and after the irradiation of gamma-rays for sterilization. The medical ceramic material is formed using a composite material containing alumina and zirconia. The composite material contains cobalt oxide. The content of cobalt oxide is set to be 0.2 wt % to 1.0 wt % with respect to 100 wt % of the composite material excluding cobalt oxide.2015-02-05
20150038320INORGANIC FIBER AND PROCESS FOR MANUFACTURING SAME - Provided is a method for producing inorganic fiber including: preparing a spinning raw material liquid which comprises an aluminum source, a calcium source, a silicon source and a spinning auxiliary, in which the content of the spinning auxiliary is, in terms of solid matter, 3 parts by mass or more relative to 100 parts by mass of the total of the aluminum source, the calcium source and the silicon source; spinning the spinning raw material liquid by a sol-gel method to obtain crude inorganic fiber; and firing the crude inorganic fiber to produce inorganic fiber that comprises 35 mass % to 88 mass % of Al2015-02-05
20150038321Activated Carbon And Coal Combustion Residue Treatment System And Method - A method for treating powdered activated carbon (PAC) and/or coal combustion residues (CCRs) by heating at least one of a spent PAC and/or a CCR to separate at least one heavy metal from the at least one of the spent PAC and/or the CCR to create a clean stream and a heavy metal stream, combining the heavy metal stream with a water soluble alkaline-earth metal sulfide to create a combined stream, and removing at least a portion of the at least one heavy metal from the combined stream. The heating may further include heating the at least one of the spent PAC and/or the CCR in an inert atmosphere. Further, the combining may include combining the heavy metal stream with the water soluble alkaline-earth metal sulfide and a catalyst and/or a surfactant or hyperdispersant.2015-02-05
20150038322ZEOLITE SSZ-70 HAVING ENHANCED EXTERNAL SURFACE AREA - A method is disclosed for preparing zeolite SSZ-70 using an imidazolium cation as a structure directing agent in conjunction with a polyethyleneimine modifier. The SSZ-70 zeolite is characterized as having an external surface area larger than conventional SSZ-70 zeolites.2015-02-05
20150038323PASS-THROUGH CATALYTIC SUBSTRATE INCLUDING POROUS CERAMIC BEVELED CORNER PORTIONS AND METHODS - A pass-through catalytic substrate can comprise a plurality of porous ceramic substrate walls defining flow channels extending between an inlet end and an outlet end of the catalytic substrate. The pass-through catalytic substrate can include a plurality of porous ceramic beveled corner portions positioned at intersecting corners of the substrate walls within the flow channels. In one example, the porous ceramic beveled corner portions each include a heat capacity less than about 1.38 J/cm2015-02-05
20150038324CATALYST SUPPORT MATERIALS, CATALYSTS, METHODS OF MAKING THEM AND USES THEREOF - Catalyst support materials, catalysts, methods of making such and uses thereof are described. Methods of making catalyst support material include combining anatase titania slurry with i) a low molecular weight form of silica; and ii) a source of Mo to form a TiO2015-02-05
20150038325CATALYST COMPOSITION FOR EXHAUST GAS CLEANING AND CATALYST FOR AUTOMOBILE EXHAUST GAS CLEANING - The present invention is to provide an exhaust gas purification catalyst composition and a catalyst for exhaust gas purification for automobile, superior in purification performance of a carbon monoxide (CO), a hydrocarbon (HC) and nitrogen oxides (NO2015-02-05
20150038326Chemically Modified Mycological Materials Having Absorbent Properties - A method of producing an absorbent biocompatible material which comprises mixing at least one mycological material, such as a fungus or fungal tissue, with at least one lignocellulosic material to provide a biocomposite material comprising the at least one mycological material and the at least one lignocellulosic material. The biocomposite material then is contacted with at least one substance that increases the hydrophilicity of the biocomposite material, thereby providing an absorbent biocomposite material that has a variety of uses, such as absorbent materials for use in vegetation propagation and preservation, animal bedding, animal litter, filler in diapers, cold chain materials for temperature regulation, ice packs, absorbent foams and mats, such as decorative floral arrangement foams, carpet mats, and absorbent booms applied to chemical spills.2015-02-05
20150038327COMPOSITION FOR CONTROLLING PLANT DISEASES AND USE THEREOF - A composition for controlling plant diseases containing a pyridazine compound represented by Formula (I) and one or more compounds selected from a group (A) exhibits an excellent control effect against plant diseases. The present invention provides a composition for controlling plant diseases containing the pyridazine compound represented by Formula (I) and one or more compounds selected from a group (A), and a method for controlling plant diseases containing a step of applying an effective amount of the pyridazine compound represented by Formula (I) and one or more compounds selected from a group (A) to a plant or soil for cultivating a plant.2015-02-05
20150038328COMPOSITION FOR CONTROLLING PLANT DISEASES AND USE THEREOF - A composition for controlling plant diseases, containing a pyridazine compound represented by Formula (I) and ethaboxam, exhibits an excellent control effect against plant diseases. The present invention provides a composition for controlling plant diseases, containing the pyridazine compound represented by Formula (I) and ethaboxam, and a method for controlling plant diseases, including a step of applying an effective amount of the pyridazine compound represented by Formula (I) and ethaboxam to a plant or soil for cultivating a plant.2015-02-05
20150038329MESOIONIC PESTICIDES - Disclosed are compounds of Formula 1,2015-02-05
20150038330Chemical Compositions and Methodology to Enhance Plant Growth and Development - Plant seeds, seedlings, or developing plants are treated with aqueous, dry, or appropriately solvated chemical formulations composed of nucleotides or nucleosides buffered with an effective amount of non-toxic biologically compatible agents, simultaneously with an antioxidant and lipoxygenase enzyme inhibitor. The purpose is to improve or optimize seed germination rate, seedling vigor, and ultimately plant growth characteristics and yield performance. In the preferred embodiment, seeds or other plant tissues are treated with adenosine monophosphate buffered with an excess amount of phosphoric acid salts at about pH 7.0 as described in U.S. Pat. No. 4,209,316. The improvement described in this application comprises the simultaneous addition of a similar quantity of propyl gallate to the adenosine monophosphate maintaining pH around 7.0 or below. Addition of a lesser, fractional quantity of a magnesium salt, such as magnesium sulfate, is to be included in the formulation to potentiate the action of the chemical treatment if planting soil or medium is shown to be magnesium deficient.2015-02-05
20150038331RICE RESISTANT TO HPPD AND ACCASE INHIBITING HERBICIDES - Rice is described that is tolerant/resistant to a plurality of herbicides, for example, ACCase and HPPD inhibitors. Use of the rice for weed control and methods of producing tolerant/resistant rice are also described.2015-02-05
20150038332Herbicidal Isoxazolo[5,4-B]Pyridines - The invention relates to isoxazolo[5,4-b]pyridine compounds of formula I,2015-02-05
20150038333PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS - The present invention relates to a plant protective composition comprising α-hydroxy-acid or a derivative thereof. The present invention further relates to a method of protecting plants from biotrophic pathogens comprising contacting the plants with the plant protective composition.2015-02-05
20150038334SUPERCONDUCTING FILM-FORMING SUBSTRATE, SUPERCONDUCTING WIRE, AND SUPERCONDUCTING WIRE MANUFACTURING METHOD - A tape-shaped superconducting film-forming substrate is disclosed, which includes a film-forming face for forming a laminate including a superconducting layer thereon, a rear face that is a face at a side opposite to the film-forming face, a pair of end faces connected to the film-forming face and the rear face, and a pair of side faces connected to the film-forming face, the rear face, and the pair of end faces, in which each of the pair of side faces includes a spreading face that spreads toward an outer side in an in-plane direction of the film-forming face from an edge part of the film-forming face toward the rear face side. A superconducting wire and a superconducting wire manufacturing method are also disclosed.2015-02-05
20150038335CEREBROSPINAL FLUID ASSAY - The present invention is directed to methods of isolating particles, such as nucleic acid-containing particles or microvesicles, from a biological sample and extracting nucleic acids therefrom, wherein the biological sample is cerebrospinal fluid. The present invention further provides methods for aiding diagnosis, prognosis, monitoring and evaluation of a disease or other medical condition in a subject by detecting a biomarker associated with a disease or medical condition thereof.2015-02-05
20150038336METHOD FOR RELATIVE QUANTIFICATION OF NUCLEIC ACID SEQUENCE, EXPRESSION, OR COPY CHANGES, USING COMBINED NUCLEASE, LIGATION, AND POLYMERASE REACTIONS - The present invention is directed to methods for identifying the presence of one or more target nucleotide sequences in a sample that involve a nuclease-ligation reaction. In some embodiments, the ligation products formed in the nuclease-ligation process of the present invention are subsequently amplified using a polymerase chain reaction. The ligated product sequences or extension products thereof are detected, and the presence of one or more target nucleotide sequences in the sample is identified based on the detection.2015-02-05
20150038337METHODS OF SELECTING BIOLOGIC-PRODUCING CELL LINES BY NEXT GENERATION SEQUENCING - An optimized multi-step cell line screening method based on next generation sequencing (NGS) and mass spec (MS) is disclosed. The method helps reduce variants in the biologic-producing cell line and improve the efficiency of cell line development process.2015-02-05
20150038338IDENTIFICATION OF OLFACTORY RECEPTORS SENSITIVE TO DIFFERENT ODORANTS - This disclosure provides methods for identification of olfactory sensosry neurons (OSN) that recognize specific odorants. The method comprises introducing into the OSN, a permanent activity marker which exhibits a detectable and permanent change upon activation of the neuron in response to an odorant and exposure to an exteranal stimulus, such as light. The OSN can be isolated and its receptor characterized.2015-02-05
20150038339Methods And Devices For Sequencing Nucleic Acids In Smaller Batches - The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. A plurality of smaller flow cells is employed, each with a relatively small area to be imaged, in order to provide greater flexibility and efficiency.2015-02-05
20150038340METHODS FOR PREDICTING ANTI-CANCER RESPONSE - The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.2015-02-05
20150038341Digital Amplification - The identification of pre-defined mutations expected to be present in a minor fraction of a cell population is important for a variety of basic research and clinical applications. The exponential, analog nature of the polymerase chain reaction is transformed into a linear, digital signal suitable for this purpose. Single molecules can be isolated by dilution and individually amplified; each product is then separately analyzed for the presence of pre-defined mutations. The process provides a reliable and quantitative measure of the proportion of variant sequences within a DNA sample.2015-02-05
20150038342METHODS AND COMPOSITIONS FOR MULTIPLEX PCR - The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.2015-02-05
20150038343METHODS AND COMPOSITIONS FOR MULTIPLEX PCR - The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.2015-02-05
20150038344Method of Preparing a Nucleic Acid Library - A method of preparing a nucleic acid library in droplets in contact with oil, including: (a) blunt-ending nucleic acid fragments in a droplet in the oil to yield blunt-ended nucleic acid fragments; (b) phosphorylating the blunt-ended nucleic acid fragments in a droplet in the oil to yield phosphorylated nucleic acid fragments; coupling A-tails to the phosphorylated nucleic acid fragments in a droplet in the oil to yield A-tailed nucleic acid fragments; and (d) coupling nucleic acid adapters to the A-tailed nucleic acid fragments in a droplet in the oil to yield the nucleic acid library comprising adapter-ligated nucleic acid fragments.2015-02-05
20150038345Random Array DNA Analysis by Hybridization - The invention relates to methods and devices for analyzing single molecules, i.e., nucleic acids. Such single molecules may be derived from natural samples, such as cells, tissues, soil, air and water without separating or enriching individual components. In certain aspects of the invention, the methods and devices are useful in performing nucleic acid sequence analysis by probe hybridization.2015-02-05
20150038346MONITORING IMMUNE RESPONSIVENESS TO CANCER VACCINATION - The invention is direct to a method for determining a cancer patient's immune responsiveness to anti-cancer vaccination. In one aspect, for each of a plurality of vaccinations, pairs of clonotype profiles are obtained, one immediately prior to vaccination and one during the period of peak immune response, usually within two to twenty days after the vaccination. Responsiveness is correlated to successive increases in identical clonotypes within each pair of clonotype profiles in at least two successive vaccinations.2015-02-05
20150038347SURFACE ENHANCED RAMAN SPECTROSCOPY - Rapid surface enhanced Raman spectroscopy (SERS) assays for ultratrace pathogen detection are provided. One-particle and two-particle sensor assays (e.g., biosensor assays) are provided. In one implementation, for example, an assay forms and concentrates a DNA hybridization complex incorporating paramagnetic particles and Raman active noble metal (e.g., gold, silver and/or copper) nanoparticles (two-particle sensor) or noble metal coated paramagnetic particles that provide both a SERS substrate and magnetic capture ability in a single sensor particle via a noble metal-coated paramagnetic particle, such as a gold-coated paramagnetic particle (one-particle sensor).2015-02-05
20150038348MICROBIAL BIOINDICATORS OF HYDROCARBONS IN WATER AND IN MARINE SEDIMENTS AND METHODS FOR MAKING AND USING THEM - In alternative embodiments, the invention provides products of manufacture and compositions, e.g., nucleic acid probes, for use as identifying agents or indicators to detect the presence of a hydrocarbon in a sample, e.g., in marine sediments, muds, sands and the like, or in a solution, e.g., an aqueous solution, such as a production water, fresh water, underground water or seawater. In alternative embodiments, the invention provides compositions, e.g., nucleic acid probes or primers or primer pairs, for use as sensors and/or identifying agents to detect the presence of a hydrocarbon in a sample (e.g., in fresh water, underground water or seawater, or a marine mud, sand or sediment), where the presence of the hydrocarbon indicates e.g., the presence of a subsurface oil, petroleum or gas accumulation or deposit. In alternative embodiments, the invention provides compositions and methods for use as tools for offshore oil exploration activities.2015-02-05
20150038349Methods and Molecular Pharmacodynamic Biomarkers for Multiple Signaling Pathways in Response to Carboxyamidotriazole Orotate - This invention provides methods, pharmacodynamics biomarker signatures for multiple signaling pathways in a cell sample such as anagen hair, in response to carboxyamidotriazole orotate (CTO) from a subject. CTO has demonstrated response in several cancers having different genomic mutations in clinical studies. This invention provides a diagnostic and prognostic assay for monitoring response to CTO ranging from −100 fold to +25 fold differential expression in several transcriptional signatures associated with tumor inhibition including EGFR, MEK, HDAC, RAS, GFS, WNT, HSP90 or non-voltage dependent calcium signaling, while inducing tumor suppressors signatures such as P53 or EGR1 in the anagen hair assay.2015-02-05
20150038350Method for Determining Condition of Oral Cavity and Analytical Tool, Apparatus, and Program Used for the Method - Means of determining the condition of the oral cavity in a subject is provided. The condition of the oral cavity in the subject is determined by using an analytical tool comprising the following (A), (B), and (C): 2015-02-05
20150038351Gene Signatures That Predispose Or Protect Individuals From Low-Dose Radiation Induced Breast Cancer Or Are Associated with Disease-Free Survival - A method for identifying sensitivity to low-dose ionizing radiation and cancer patient prognosis. Several predictor panels of genes that are predictive for increased or decreased susceptibility for LD-induced cancer and predictor panel that are predictive for increased or decreased disease free survival in women who are newly diagnosed with breast cancer.2015-02-05
20150038352ANALYSIS OF METHYLATION USING NUCLEIC ACID ARRAYS - Arrays for genome-wide analysis of methylation are disclosed. In a preferred aspect arrays comprising a plurality of probes complementary to a plurality of identified CpG islands in the human, mouse and rat genome are disclosed. The arrays may be used to detect methylation within CpG islands in samples from human, mouse and rat genomes.2015-02-05
20150038353MOLECULAR MARKERS FOR DETECTING NOSEMA INFECTION - The present invention provides a molecular marker for detecting 2015-02-05
20150038354FULL LENGTH ANTIBODY DISPLAY SYSTEM FOR EUKARYOTIC CELLS AND ITS USE - Herein is reported a method of selecting a cell expressing a bispecific antibody comprising the steps of (a) generating a population of eukaryotic cells by transduction with a population of lentiviral virus particles, whereby each cell of the population of cells displays a membrane-bound full length antibody which is encoded by the lentiviral nucleic acid, and which specifically binds to two or more antigens or two or more epitopes on the same antigen, and (b) selecting from the population of eukaryotic cells a cell depending on the properties of the displayed membrane-bound full length antibody, whereby each lentiviral virus particle of the population of lentiviral virus particles comprises a bicistronic expression cassette comprising the EV71-IRES for the expression of the membrane-bound antibody.2015-02-05
20150038355MULTIPLEX BLOCKER BEADS FOR IMMUNOASSAYS - Provided are methods and compositions for immunoassay with improved specificity. The presently disclosed bead-based blocking agents reduce the interference associated with the samples and reagents of such assays.2015-02-05
20150038356GENETIC ASSAYS - Provided herein are methods, compositions, systems, and kits for recombination assays, many of which involve amplification reactions such as PCR or droplet digital PCR.2015-02-05
20150038357PROGNOSIS FOR GLIOMA - Disclosed is a method of determining the survival prognosis of a patient afflicted by a glioma. The method includes assessing the level of expression of one or more specific gene in cells of the glioma.2015-02-05
20150038358METHODS FOR DETECTING TRISOMY 21 - Methods for determining whether a subject, such as a fetus, has Down syndrome are described. In one embodiment, the methods include detecting one or more biomarkers in a biological sample, and determining whether the expression of the biomarkers is altered when compared to expression of the biomarkers in one or more subjects that do not have trisomy 21. In one embodiment, the biological sample is a blood sample, and the biomarkers are cell free plasma RNAs.2015-02-05
20150038359METHOD OF PREDICTING OUTCOME IN CANCER PATIENTS - A method of prognosis for a mammal with cancer is provided. The method includes the steps of determining in a biological sample obtained from the mammal the expression level of each biomarker of the group DSTN, TDRD3, RGS4, MYO1E, RPL3, Hypothetical FLJ13769, ANP32C, MC2R, DKFZp434L092, GPR27, HPS and LCP1; comparing the expression level of each biomarker with the expression level of a housekeeping gene; and rendering a prognosis for the mammal of a greater than 50% survival for an extended period of time when the expression level of DSTN, TDRD3, RGS4, MYO1E, RPL3(1), RPL3(2), RPL3(3), Hypothetical FLJ13769 and ANP32C is decreased in comparison to the expression of the housekeeping gene, and the expression level of MC2R, DKFZp434L092, GPR27, HPS5 and LCP1 is increased in comparison to the expression of the housekeeping gene.2015-02-05
20150038360Method for Multiplex-Detecting Chronic Myelogenous Leukemia Gene Using Cleavable Probe - One embodiment of the present invention provides a detection kit for detecting a chronic myelogenous leukemia (CML) gene expression, wherein the detection kit includes a primer set which is specifically bound to the CML gene; and a cleavable probe which is specifically bound to the inside of a CML gene amplification product which is amplified by the primer set. Another embodiment of the present invention provides a method of measuring the CML gene expression by using the detection kit according to one embodiment of the present invention. The method according to one embodiment of the present invention is used to efficiently detect a low CML gene expression for CML diagnosis and prognosis diagnosis.2015-02-05
20150038361APPARATUS, METHODS, AND APPLICATIONS FOR POINT OF CARE MULTIPLEXED DIAGNOSTICS - Methods and systems for colorimetric detection of a target. Nucleic acid is obtained from a sample potentially containing two pathogens of interest, and is contacted with a plurality of nanoparticles. A first portion of the plurality of nanoparticles are functionalized with oligonucleotides complementary to a first region of the first target and oligonucleotides complementary to a second region of the first target, and a second portion of the plurality of nanoparticles are functionalized with oligonucleotides complementary to a first region of the second target and oligonucleotides complementary to a second region of the second target. The presence of the target nucleic acid causes a detectable colorimetric change, thereby diagnosing the presence of the pathogen.2015-02-05
20150038362High-Throughput Method For Sialic Acid Quantitation - The present invention relates to a method for specifically measuring sialylation of a biomolecule of interest without the interference of other biomolecules present in the sample.2015-02-05
20150038363Method for Stimulating T Cell and Use Thereof - An object of the present invention is to stimulate a T cell without using a peptide/MHC tetramer. In the present invention, the step of supplying an antigen peptide to a T cell having a T cell receptor (TCR) that can recognize the antigen peptide on cell surface to form a complex of a major histocompatibility complex (MHC) molecule on the cell surface of the T cell and the antigen peptide is used, and the T cell is stimulated through recognition by TCR of the antigen peptide as the MHC molecule-antigen peptide complex on the cell surface of the same T cell. Such a stimulating and activating method would be applicable to not only T cells, but also various cells. According to the present invention, an antigen-specific T cell can be identified without establishing any antigen-specific T cell strain, and without using such a reagent as MHC/peptide tetramer. That is, a cancer-specific T cell can be efficiently and conveniently identified.2015-02-05
20150038364MICROARRAY SUBSTRATE, MICROARRAY, MICROFLUIDIC SYSTEM AND METHODS FOR PREPARING THE SAME - A microarray substrate including a piece of fluoropolymer whose surface is modified with polydopamine, in which the polydopamine forms an array of microspots on the surface of the fluoropolymer piece, and allows immobilization of molecules or cells. A microarray including the substrate, a microfluidic system designed for dispensing reagents onto selected locations on the surface of substrates, and a method for preparing the substrate and the microarray, in which a dopamine solution is dispensed onto the fluoropolymer piece using the microfluidic system, and forms an array of polydopamine microspots serving as the reaction sites for microarray analysis.2015-02-05
20150038365LUNG CANCER BIOMARKERS - The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.2015-02-05
20150038366Immunoassay for Phenethylamines of the 2C and DO Sub-Families - Immunoassay methods and their requisite components for the detection and determination of phenethylamines of the 2C and DO sub-families are described.2015-02-05
20150038367METHODS FOR DETECTING GENE DYSREGULATIONS - Described herein are methods, compositions and kits directed to the detection of gene dysregulations such as those arising from gene fusions and/or chromosomal abnormalities, e.g., translocations, insertions, inversions and deletions. Samples containing dysregulated gene(s) of interest may show independent expression patterns for the 5′ and 3′ regions of the gene. The methods, compositions and kits are useful for detecting mutations that cause the differential expression of a 5′ portion of a target gene relative to the 3′ region of the target gene.2015-02-05
20150038368Biomolecule Immobilization On A Surface via Hydrophobic Interactions - A method, apparatus, or system for generating a pattern of polynucleotides on a substrate. The method includes providing a substrate having a hydrophobic surface. The method further includes conjugating a polystyrene moiety to a polynucleotide and applying a polystyrene-polynucleotide conjugate to create a plurality of reaction spots on the hydrophobic surface of the substrate. An apparatus includes a substrate with at least one polystyrene-polynucleotide conjugate on a surface of the substrate. A system can analyze a polystyrene-polynucleotide conjugate and the system may perform PCR.2015-02-05
20150038369Method and Kit for Diagnosing Autism Using Gene Expression Profiling - This invention relates to DNA microarray technology, and more specifically to methods and kits for identifying autism and autism spectrum disorders in humans.2015-02-05
20150038370Methods for Antibody Engineering - The invention provides a method for identifying positions of an antibody that can be modified without significantly reducing the binding activity of the antibody. In many embodiments, the method involves identifying a substitutable position in a parent antibody by comparing its amino acid sequence to the amino acid sequences of a number of related antibodies that each bind to the same antigen as the parent antibody. The amino acid at the substitutable position may be substituted for a different amino acid without significantly affecting the activity of the antibody. The subject methods may be employed to change the amino acid sequence of a CDR without significantly reducing the affinity of the antibody of the antibody, in humanization methods, or in other antibody engineering methods. The invention finds use in a variety of therapeutic, diagnostic and research applications.2015-02-05
20150038371TRANSFORMED HUMAN PLURIPOTENT STEM CELLS AND ASSOCIATED METHODS - The present disclosure provides transformed human pluripotent stem cell (t-hPSC). t-hPSCs are not dependent on Oct4 for renewal and survival, however exhibit a sensitivity to reduced levels of the transcription factor Nanog. Also provided are methods of culturing cells for use in a cell-based screening assay comprising placing one or more transformed human pluripotent stem cells into a receptacle and culturing said stem cells in the receptacle to form a monolayer of stem cells without cell overlap. Methods of screening compounds using t-hPSCs are also described.2015-02-05
20150038372METHODS, MICROFLUIDIC DEVICES, AND SYSTEMS FOR DETECTION OF AN ACTIVE ENZYMATIC AGENT - Embodiments of the present invention provide methods, microfluidic devices, and systems for the detection of an active target agent in a fluid sample. A substrate molecule is used that contains a sequence which may cleave in the presence of an active target agent. A SNAP25 sequence is described, for example, that may be cleaved in the presence of Botulinum Neurotoxin. The substrate molecule includes a reporter moiety. The substrate molecule is exposed to the sample, and resulting reaction products separated using electrophoretic separation. The elution time of the reporter moiety may be utilized to identify the presence or absence of the active target agent.2015-02-05
20150038373DE NOVO SYNTHESIZED GENE LIBRARIES - De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.2015-02-05
20150038374DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS - The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detection phase. The ligation phase utilizes a ligation detection reaction between one oligonucleotide probe, which has a target sequence-specific portion and an addressable array-specific portion, and a second oligonucleotide probe, having a target sequence-specific portion and a detectable label. After the ligation phase, the capture phase is carried out by hybridizing the ligated oligonucleotide probes to a solid support with an array of immobilized capture oligonucleotides at least some of which are complementary to the addressable array-specific portion. Following completion of the capture phase, a detection phase is carried out to detect the labels of ligated oligonucleotide probes hybridized to the solid support.2015-02-05
20150038375METHODS AND COMPOSITIONS FOR MULTIPLEX PCR - The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.2015-02-05
20150038376THYROID CANCER BIOMARKER - The methods provided herein use microarray data for feature selection and then use selected targets to generate industry standard qPCR arrays with new clinical sample assay data so order to build a classification model. This multi-step method overcomes the disadvantages of traditional biomarker identification.2015-02-05
20150038377Microfluidic Transfer Pins - A liquid dispenser for a microfluidic assay system is described. The dispenser includes at least one transfer pin for transferring a microfluidic sample of liquid to a target receptacle. A pin tip at one end of the transfer pin is structured to cooperate with an opening in the target receptacle. The tip uses a high voltage potential to transfer the sample from the pin to the receptacle.2015-02-05
20150038378BIOCOMPATIBLE GRAPHENE SENSOR - A graphene biosensor is formed on an electrically insulating substrate with a single-layer graphene sheet arranged between two metallic electrodes. The graphene sheet is in electrical contact with the metallic electrodes. The graphene sheet has perforations creating edges in the graphene sheet. The perforations may be holes on a micrometer scale or in a nanometer scale. The biosensor can be configured as an ISFET. The graphene sheet may comprise affinity probes immobilized on the edges for attaching specific molecules to the graphene sheet. Several graphene sheets may be arranged in a microarray with different affinity probes on different graphene sheets. The sensor may also be arranged on the distal end of a catheter for in situ measurements in a body vessel.2015-02-05
20150038379METHODS AND DEVICES FOR MICRO-ISOLATION, EXTRACTION, AND/OR ANALYSIS OF MICROSCALE COMPONENTS - Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation apparatus described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation apparatus can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation apparatus can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation apparatus can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device. Also included are methods for selectively isolating cellular material using the apparatuses described herein, as are methods for biochemical analysis of individual regions of interest of cellular material using the devices described herein. Further included are methods of making masking arrays useful for the methods described herein.2015-02-05
20150038380GEAR HAVING EXCELLENT SEIZING RESISTANCE - This gear has a predetermined chemical composition and has, in a surface-layer part, a texture of tempered martensite and/or tempered bainite and a steel material texture in which retained austenite exists in 1-10% by area percentage and in which a carbide is deposited in at least 5% by area percentage, and the nitrogen content at a depth of 20 μm below the surface is 2.0-6.0%. Thus, a gear that achieves even better seizing resistance in a power transmission part subjected to high rotation and high slippage and using a low-kinematic-viscosity lubricating oil is provided.2015-02-05
20150038381LUBRICATING OIL COMPOSITION FOR REFRIGERATING MACHINES - A lubricating oil composition for refrigerating machines contains a base oil and an additive in a form of a coumarin compound. When the present lubricating oil composition for refrigerating machines is used in refrigerating equipment such as an open-type automobile air-conditioner, an electric automobile air-conditioner, a gas heat pump, other air-conditioning equipment, a refrigerating machine, a vending machine, a showcase, a water-heating system and a refrigerating/heating system, it is possible to detect the leakage of a refrigerant with a long-lasting stability. Therefore, when an unsaturated chlorofluorocarbon refrigerant with a poor stability is used in the above-listed equipment, the present lubricating oil composition for refrigerating machines is significantly advantageous.2015-02-05
20150038382GEAR OIL COMPOSITIONS - A gear oil composition, a method for operating an automotive gear, and a method for improving performance of a gear oil that includes a) a major amount of a base oil having a lubricating viscosity; b) a polysulfide extreme pressure agent; and c) a reaction product of an acylated copolymer and a polyamine.2015-02-05
20150038383METHOD FOR PREVENTING EXHAUST VALVE SEAT RECESSION - A method for preventing or inhibiting exhaust valve seat recession in a natural gas fueled internal combustion engine is disclosed. The method involves lubricating the engine with a lubricating oil composition comprising (a) a major amount of an oil of lubricating viscosity, and (b) a minor amount of a natural gas engine oil additive package, wherein the lubricating oil composition is substantially free of each of any zinc compounds and alkaline earth metal salts of a condensation product of an alkylene polyamine, an aldehyde and a substituted phenol.2015-02-05
20150038384LUBRICATING OIL COMPOSITION FOR SHOCK ABSORBER - To provide a lubricating oil composition for a shock absorber for preventing wearing a piston rod and a guide bush in a shock absorber, which composition lowers the friction coefficient at the interface between bronze and chromium and reduces wear area of bronze.2015-02-05
20150038385Method of Lubricating a Driveline Device - The invention provides a method of lubricating a mechanical device by supplying a lubricating composition containing an oil of lubricating viscosity and a compound having 2 to 20 hydroxy-carboxylic acid residues. The invention further relates to the use of the compound in a driveline device to provide at least one of antiwear performance, friction modification (particularly for enhancing fuel economy).2015-02-05
20150038386TERPENE ALCOHOLS FOR USE IN FRAGRANCE COMPOSITIONS AND PERFUMED PRODUCTS - Compounds of formula (I)2015-02-05
20150038387SUPERABSORBING GEL FOR ACTINIDE, LANTHANIDE, AND FISSION PRODUCT DECONTAMINATION - The present invention provides an aqueous gel composition for removing actinide ions, lanthanide ions, fission product ions, or a combination thereof from a porous surface contaminated therewith. The composition comprises a polymer mixture comprising a gel forming cross-linked polymer and a linear polymer. The linear polymer is present at a concentration that is less than the concentration of the cross-linked polymer. The polymer mixture is at least about 95% hydrated with an aqueous solution comprising about 0.1 to about 3 percent by weight (wt %) of a multi-dentate organic acid chelating agent, and about 0.02 to about 0.6 molar (M) carbonate salt, to form a gel. When applied to a porous surface contaminated with actinide ions, lanthanide ions, and/or other fission product ions, the aqueous gel absorbs contaminating ions from the surface.2015-02-05
20150038388Granulated Foam Control Agent For The Rinse Cycle Using Siloxane Wax - A granulated antifoam composition comprising an antifoam, a siloxane wax binder, and a carrier. The antifoam includes a hydrophobic fluid wherein the hydrophobic fluid has a surface tension which is greater than or approximately equal to the dynamic surface tension of an aqueous dispersion of the detergent at above the critical micelle concentration of the surfactant and less than about 62 mN/m. The antifoam further includes a finely divided solid hydrophobic filler dispersed in the hydrophobic fluid.2015-02-05
20150038389AQUEOUS CLEANING COMPOSITIONS INCLUDING AN ALKYL 3-HYDROXYBUTYRATE - Cleaning compositions and methods of making and using the same are provided. The cleaning compositions of the present invention may include at least one alkyl 3-hydroxybutyrate and water, optionally including at least one surfactant and one or more additional additives. The cleaning compositions of the present invention, which are non-toxic and environmentally benign, can be useful to remove many types of soils from a range of different substrates in a variety of domestic, industrial, and/or institutional applications.2015-02-05
20150038390FREESTANDING DETERGENT COMPOSITION NOT REQUIRING AN AUTOMATED DISPENSER - A solid controlled release composition according to the present invention includes at least one cellulosic material, water, at least one active ingredient, and optionally at least one of a saccharide, sugar alcohol or salt. The active ingredient can be a polycarboxylic acid.2015-02-05
20150038391AQUEOUS CLEANING COMPOSITIONS HAVING ENHANCED PROPERTIES - Cleaning compositions and methods of making and using the same are provided. The cleaning compositions of the present invention are both non-toxic and environmentally benign, and are effective at removing both hydrophobic and hydrophilic soils from a wide range of substrate types, including metal, glass, painted wall board, vinyl, concrete, and many others. The cleaning compositions of the present invention may be useful in a variety of domestic, industrial, and/or institutional applications.2015-02-05
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