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06th week of 2015 patent applcation highlights part 40
Patent application numberTitlePublished
20150037387Biomatrix Composition and Methods of Biomatrix Seeding - Apparatus and methods are described for generating autologous tissue grafts, the apparatus including a point of care SVF isolation unit that includes a tissue digestion chamber in fluid communication with a lipid separating chamber, whereby SVF cells are isolated without centrifugation; and a cell seeding chamber in fluid communication with the SVF isolation unit, said cell seeding chamber adapted to support a cell scaffold. Methods and materials for cell seeding, including through the provision of micro rough scaffold surfaces, are also provided.2015-02-05
20150037388EDIBLE SLOW DISSOLVING FILM FOR TREATING ORAL ULCERATIONS - The invention relates, in one aspect, to a mucoadhesive edible slow dissolving film comprising a salt of alginic acid, an edible cellulose derivative, an edible protein, and edible polymer delaying the dissolution in a physiological fluid of the edible film selected from polyvinylpyrrolidone, a carboxyvinyl polymer and mixtures thereof, in an amount effective to delay the dissolution time of the film in a biological fluid. The edible film is suitable for cicatrizing oral ulcerations or lesions or for forming a layer on oral mucosae or gingiva affected by ulcerations or lesions for protecting against mechanical abrasions, infections or caustic agents.2015-02-05
20150037389Edible Product Comprising Reconstituted Plant Material - The present invention relates to an edible product, which comprises a fibrous plant product and a plant extract applied thereto. Further, the invention relates to a corresponding method for producing said edible product and its use in at least one of food, food supplement, medicinal, cosmetic, well-being, nutraceutical or phytotherapeutical applications. The plants used may be all plants comprising one or more substances of interest for an edible product.2015-02-05
20150037390SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY - Cationic, anionic, and/or zwitterionic bis-urea compounds self-assemble by non-covalent interactions in aqueous solution to form high aspect ratio nanofibers. The nanofibers reversibly bind drugs by non-covalent interactions, forming drug compositions for exhibiting sustained release of the drug.2015-02-05
20150037391Local administration of gallium compositions to treat pain - Provided are methods of treating pain, including neuropathic pain, in human and veterinary individuals. These methods employ locally administrable pharmaceutical gallium compositions, including pharmaceutical gallium compositions suitable for administration to the skin and mucous membranes. The compositions comprise pharmaceutically acceptable gallium compounds, such as gallium maltolate or gallium nitrate, together with pharmaceutically acceptable carriers suitable for local administration, including those suitable for topical administration. The administration of such compositions provides relief from pain, itching, allodynia, hyperalgesia, and related symptoms.2015-02-05
20150037392LIQUID-PERMEABLE PRIMARY DRESSING HAVING A FRACTION OF HEAVY METAL - The present invention relates to a fluid-permeable primary dressing in strip form, having pores, perforations or honeycomb lattices, which enable the passage of fluid, further having a content of at least one heavy metal present in elemental or ionic form.2015-02-05
20150037393ADHESIVE PATCHES FOR USE IN SUNLESS TANNING - Adhesive patches for protecting skin imperfections such as age spots, from discoloring and/or darkening during sunless tanning are provided herein. The adhesive patches are sized and shaped to fully or partially cover the skin imperfections during application of a sunless tanning product such to provide a user with uniform color development over the entire skin, and, in some embodiments, to allow for the skin imperfection to appear less visible.2015-02-05
20150037394DRUG DELIVERY FORMULATIONS - Mixtures of C2015-02-05
20150037395TRANSDERMAL HORMONE DELIVERY SYSTEM: COMPOSITIONS AND MTEHODS - A transdermal hormone delivery system (THDS) is disclosed. The THDS is useful for control of fertility and as therapy for a variety of diseases and conditions treatable by robust delivery of progestin and estrogen hormones, particularly the progestin, levonorgestrel. The THDS comprises a backing layer, an adjoining adhesive polymer matrix comprising an effective amount of at least a progestin hormone, delivery of which is enhanced by one or more skin permeation enhancing agents present in pre-determined amounts. The THDS is capable of providing effective daily doses of progestin and estrogen hormones from a small surface area in contact with the skin, e.g., less than 20 square centimeters. Methods of fertility control and various types of hormone replacement therapy utilizing the THDS are also disclosed.2015-02-05
20150037396Targeted Delivery of Anti-Fungal Agents - The present application discloses a targeting composition that actively targets chitin-like materials, such as those found in fungi, a drug delivery vehicle comprising a micelle that comprises the targeting composition and one or more anti-fungal drugs, and methods of using the drug delivery vehicle.2015-02-05
20150037397PHARMACEUTICAL COMPOSITIONS OF PYRIDINIUM AND QUINOLINIUM DERIVATIVES - The present invention relates to pharmaceutical compositions comprising a compound of formula (I) and a cyclodextrin or a liposome, to the process of preparing said compositions and their use for antitumor, antiviral, antiparasitic and antifungal treatment.2015-02-05
20150037398MOLECULE MIXTURE COMPRISING AN AMPHIPATHIC MOLECULE TYPE A, WHICH HAS A POSITIVE TOTAL CHARGE IN THE HYDROPHILIC RANGE, AND AN AMPHIPATHIC MOLECULE TYPE B AND A POLYPHENOL C, METHOD FOR PRODUCING SAID MOLECULE MIXTURE AND USE THEREOF - A molecule mixture comprising an amphipathic molecule of type A, which has an overall positive charge in the hydrophilic region, an amphipathic molecule of type B and a polyphenol C, the method for producing the molecule mixture, and the use thereof. The molecules of types A and B are present at a molecular ratio of A:B of 1(±0.2):1(±0.2) mol/mol. A method for producing the mixture and the use is also disclosed.2015-02-05
20150037399NOVEL USE OF PIPOXOLAN AND ITS PHARMACEUTICAL COMPOSITION - The present disclosure concerns the novel use of pipoxolan and its pharmaceutical composition. Pipoxolan is useful therapeutic drugs for pathological conditions caused by vascular smooth muscle cell proliferation and migration to relieve a body appeared vascular injury, cerebrovascular ischemia, intimal hyperplasia, atherosclerotic stenosis, cerebral ischemia, and stroke.2015-02-05
20150037400CYTOTOXIC AGENTS - A method of killing a cell that is lacking in effective p53 protein activity, particularly as compared to wild type, is provided characterised in that it comprises delivering to the cell a single stranded DNA including a portion with at least one base, internally located with respect to any 3′ and 5′ ends of the DNA, that is un-basepaired with another base in a form that is capable of being internalised by the cell.2015-02-05
20150037401siRNA Compositions and Methods for Inhibiting Gene Expression in Tumor Initiating Cells of breast Cancer - Disclosed are methods and compositions for siRNA-mediated therapy of mammalian diseases. In particular, compositions and methods are disclosed for treatment of therapy-resistant human breast cancers. In exemplary embodiments, siRNA molecules are presented that effectively knock down gene expression of one or more polynucleotides in breast cancer tumor initiating cells.2015-02-05
20150037402Methods and Compositions for Treating Gastric Disorders - Improved efficacy in treatment of gastric disorders with botulinum toxin is obtained using liposomal encapsulated botulinum formulations for topical administration of the botulinum toxin. The liposomes are typically administered in a physiologically acceptable carrier such as saline or phosphate buffered saline by application onto the surface of the tissue within into the gastrointestinal (GI) tract in need of treatment. Preferably, the formulation is applied via a roller, sponge or nozzle that is attached to an endoscope.2015-02-05
20150037403USE OF miR-23a-3p AND/OR miR-27a-3p MIMICS AS THERAPEUTIC AGENTS FOR INHIBITION OF NEURONAL APOPTOSIS FOLLOWING BRAIN INJURY - The present invention relates to a method for treating a brain injury due to a traumatic event, disease or ischemic attack in a mammal subject, wherein the method comprises administering to the mammal subject an effective amount of miR-23a-3p and/or miR-27a-3p mimics to reduce activation of Puma, Noxa and Bax therby causing a subsequent reduction in neuronal apoptosis.2015-02-05
20150037404METHODS FOR JOINT LUBRICATION AND CARTILAGE WEAR PREVENTION MAKING USE OF GLYCEROPHOSPHOLIPIDS - A method for lubricating a joint of a mammal by administering into a cavity of the joint a composition of liposomes that are multilamellar vesicles (MLV) dispersed in a fluid medium, the liposomes having a mean diameter of between about 0.8 μm to about 10 μm and including membranes of at least one glycerophospholipid (GPL) having two C2015-02-05
20150037405PHARMACEUTICAL COMPOSITIONS OF LEVODOPA AND CARBIDOPA - The present invention relates to pharmaceutical compositions of levodopa and carbidopa. In particular, the invention relates to modified release pharmaceutical compositions of levodopa and carbidopa with at least one organic acidic excipient. The invention also relates to processes for the preparation of such compositions and use thereof for treatment of Parkinson's disease.2015-02-05
20150037406NOVEL CRYSTALLINE FORM OF SITAGLIPTIN SULFATE - A novel crystalline form of sitagliptin sulfate is provided. In addition, a method for obtaining the crystalline form, pharmaceutical compositions comprising the novel crystalline form and the crystalline form for use as a medicament are provided.2015-02-05
20150037407METHOD TO IMPROVE THE SAFETY OF HANDLING OF HIGH POTENCY DRUGS IN SOLID DOSAGE FORMS WITHOUT CHANGING THEIR EFFICACY - A method to improve the safety of handling of drug substances that are dispensed as solid oral dosage forms is described that does not alter the drug-release profile and the therapeutic efficacy of the pharmaceutical product.2015-02-05
20150037408Delayed Release Pharmaceutical Compositions of Salsalate - The present invention relates to modified release pharmaceutical compositions comprising salsalate. The invention also relates to processes for the preparation of such compositions.2015-02-05
20150037409CONTROLLED RELEASE HYDROCODONE FORMULATIONS - A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and controlled release material.2015-02-05
20150037410PHARMACEUTICAL COMPOSITIONS OF RANOLAZINE AND DRONEDARONE - The present disclosure relates to a solid composition comprising ranolazine and a spray-dried phosphoric acid salt of dronedarone in a bilayer tablet.2015-02-05
20150037414Stable controlled release pharmaceutical compositions containing fenofibrate and pravastatin - A controlled Release Pharmaceutical composition comprising an effective amount of Pravastatin and Fenofibrate, characterised in that the difference, in absolute value, between the times of maximal concentration (T2015-02-05
20150037415PROCESS FOR THE PREPARATION OF A SOLID, ORALLY ADMINISTRABLE PHARMACEUTICAL COMPOSITION - The present invention relates to a process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, and its use for the prophylaxis and/or treatment of diseases.2015-02-05
20150037416HEMOSTATIC DEVICE - A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.2015-02-05
20150037417MORPHINE POLYMER RELEASE SYSTEM - A pharmaceutical composition for controlled release of an active substance is provided. The active substance is released into an aqueous medium by erosion of at least one surface of the composition. The composition comprises i) a matrix comprising a) polymer or a mixture of polymers, b) an active substance and, optionally, c) one or more pharmaceutically acceptable excipients, and ii) a coating.2015-02-05
20150037418COSMETIC COMPOSITION - A cosmetic composition, comprising the following components (A), (B), (C), and (D):2015-02-05
20150037419Functional PLA-PEG Copolymers, the Nanoparticles Thereof, Their Preparation and Use for Targeted Drug Delivery and Imaging - Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging The present invention concerns novel functional PEG-PLA containing copolymers, the nanoparticles containing the same, their process of preparation and their use for site specific targeted drug delivery and imaging.2015-02-05
20150037420Sustained Release Formulation Comprising Octreotide and Two or More Polyactide-co-glycolide Polymers - The present invention relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and two or more different polylactide-co-glycolide polymers (PLGAs).2015-02-05
20150037421ARRDC1-MEDIATED MICROVESICLES (ARMMS) AND USES THEREOF - The invention provide isolated arrestin domain-containing protein 1 (ARRDC1)-mediated micro vesicles (ARMMs). Methods for generating and for isolating ARMMs are also provided herein. ARMMs can be used to deliver agents, for example, nucleic acids (e.g., siRNAs, microRNAs, lincRNAs), proteins (e.g., transcription factors, chromatin modulators, kinases, phosphorylases, or recombinases), or small molecules to target cells in vitro and in vivo, and methods for such ARMM-mediated delivery are provided herein. Diagnostic and therapeutic methods using ARMMs are also described herein.2015-02-05
20150037422COMPOSITIONS AND METHODS FOR OCULAR DELIVERY OF A THERAPEUTIC AGENT - Embodiments of various aspects described herein are directed to silk-based compositions for ocular delivery of at least one active agent, e.g., at least one therapeutic agent and methods of using the same. In some embodiments, the silk-based compositions can provide sustained release of at least one therapeutic agent to at least a portion of an eye. Thus, some embodiments of the silk-based compositions can be used for treatment of an ocular condition, e.g., age-related macular degeneration.2015-02-05
20150037423ORALLY-DISINTEGRATING SOLID PREPARATION - The present invention provides an orally-disintegrating solid preparation such as a tablet produced by tabletting fine granules showing controlled release of a pharmaceutically active ingredient and an additive, and the like, and the orally-disintegrating solid preparation containing fine granules coated with a coating layer containing a polymer affording a casting film having an elongation at break of about 100-about 700%. With the preparation, breakage of fine granules during tabletting can be suppressed in the production of an orally-disintegrating solid preparation containing fine granules showing controlled release of a pharmaceutically active ingredient.2015-02-05
20150037424SUSTAINED RELEASE ORAL SOLID PREPARATION - Provided is a sustained release oral solid preparation comprising aripiprazole or a salt thereof as an active ingredient described below, and a method for producing the sustained release oral solid preparation.2015-02-05
20150037425POWDER COMPOSITIONS FOR INHALATION - The present invention relates to pharmaceutical powders for inhalation produced by a method consisting of a first step of mixing particles of a force-controlling agent selected from a salt of a fatty acid with particles of one or more pharmacologically active materials and a second step of sieving or blending the powder with a carrier material.2015-02-05
20150037426MODIFIED STARCH MATERIAL OF BIOCOMPATIBLE HEMOSTASIS - A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.2015-02-05
20150037427NANO DELIVERY SYSTEMS - The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either hydrophobic or hydrophilic, from stable nanoparticles of opposite characteristics. The protection of the active agent was achieved by loading the agent to be protected, into nanocarriers, which were subsequently encapsulated into sub-micron nanoparticles. The sub-micron nanoparticles formation has been successfully achieved by the use of novel nano spray techniques.2015-02-05
20150037428GEOMETRICALLY ENGINEERED PARTICLES AND METHODS FOR MODULATING MACROPHAGE OR IMMUNE RESPONSES - Disclosed herein are geometrically engineered particles having varied shapes and sizes and surface charge which can incorporate drugs and/or other biomaterials for targeted delivery, such as pulmonary delivery. The size, shape, etc. of a particle can be designed and corresponding particles can be prepared that target or de-target immunological responses to the particles themselves, for example, the response of alveolar macrophages. Methods of modulating immune responses by utilizing the particles are also disclosed. The particles can be composed substantially of therapeutic, drug and polymer or can comprise polymers and proteins. The particles may also be composed of diagnostic agents and additional biomaterials to confer aerosolization and cellular uptake properties. The particles also may have a range of physical features such as fenestrations, angled arms, asymmetry and surface roughness, charge which alter the interactions with cells and tissues.2015-02-05
20150037429Controlled Release Microparticles - Formulations for controlled, sustained release of biologically active agents for the treatment of ocular disorders have been developed. These formulations are based on solid microparticles formed of the combination of biodegradable, synthetic polymers such as poly(lactic acid) (PLA), poly(glycolic acid) (PGA), and copolymers thereof. The microparticles are characterized by low burst levels and efficient drug loading and sustained release.2015-02-05
20150037430FORMULATION OF A BLOOD COMPOSITION THAT IS RICH IN PLATELET AND/OR GROWTH FACTORS AND CONTAINS GELLED PROTEINS, AND A METHOD FOR ITS PREPARATION - Formulation comprising, or derived from, an initial blood composition, wherein the formulation is rich in platelets and/or growth factors and proteins originating from the initial blood composition, and wherein the proteins are in a gelled state. The invention also refers to method for preparing the formulation, comprising the steps of heating and then cooling the initial blood composition at certain temperatures and times. Among other advantages, the formulation in accordance with the invention is biocompatible and biodegradable, presents the desirable biological or medical properties provided by the presence of platelets or growth factors, and also presents high dimensional stability over time.2015-02-05
20150037431USE OF PLATELET RICH PLASMA COMPOSITION IN THE TREATMENT OF CARDIAC CONDUCTION ABNORMALITIES - Methods and kits for treating a cardiac arrhythmia using a platelet rich plasma (PRP) composition are provided. Any type of arrhythmia may be treated using the PRP composition. The PRP composition may comprise PRP developed using blood collected from a patient suffering the cardiac arrhythmia. The PRP composition may be buffered to a physiological pH and may include one or more anti-arrhythmic agents, anti-coagulants, or other drugs. The PRP composition may be delivered using a nebulizer, minimally invasively, or surgically.2015-02-05
20150037432SELF-ASSEMBLY OF COLLAGEN FIBERS FROM DERMIS, FASCIA AND TENDON FOR TISSUE AUGMENTATION AND COVERAGE OF WOUNDS AND BURNS - The present invention is a composition of a self-assembly of collagen fibers made from a plurality of sized pieces of a source material. The source material made from animal or human tissue selected from one of dermis, tendon, fascia or dura mater. The self-assembly occurring by induction of a magnetic field in a liquid medium.2015-02-05
20150037433METHOD FOR PREPARING BIOLOGICAL TISSUE - A method for preparing tissue for medical applications, in particular tissue for use for an artificial heart valve, wherein the method has the steps of decellularizing the tissue by means of a detergent and subsequently cross-linking the collagen fibers of the tissue by means of a suitable cross-linking agent. At least one lipopeptide, such as surfactin, for example, is used as the detergent for decellularization.2015-02-05
20150037434BIOMATERIALS DERIVED FROM TISSUE EXTRACELLULAR MATRIX - Region-specific extracellular matrix (ECM) biomaterials are provided. Such materials include acellular scaffolds, sponges, solutions, and hydrogels suitable for stem cell culture.2015-02-05
20150037435CULTURE MEDIUM OF ADIPOSE-DERIVED STEM CELL, METHOD FOR PREPARING THE SAME, AND COMPOSITION INCLUDING THE SAME FOR PROMOTING HAIR GROWTH - Provided are a culture medium of an adipose-derived stem cell, a method for preparing the same, and a composition for promoting hair growth, in which the composition includes the culture medium. The adipose-derived stem cell (ADSC-T) according to the present invention exhibits long lifespan, improved cell proliferation rate, and extended proliferation period, as compared with a primary adipose-derived stem cell (ADSC), and thus, the adipose-derived stem cell (ADSC-T) can be usefully used for the study about the adipose-derived stem cell and the mass production of the culture medium of the adipose-derived stem cell. In addition, according to the present invention, the culture medium of the adipose-derived stem cell (ADSC-T) that expresses a T antigen of SV40 exhibits excellent hair growth effectiveness and can be usefully used as a raw material for the hair loss prevention and hair growing agents.2015-02-05
20150037436ACELLULAR SOFT TISSUE-DERIVED MATRICES AND METHODS FOR PREPARING SAME - An acellular soft tissue-derived matrix includes a collagenous tissue that has been delipidated and decellularized. Adipose tissue is among the soft tissues suitable for manufacturing an acellular soft tissue-derived matrix. Exogenous tissuegenic cells and other biologically-active factors may be added to the acellular matrix. The acellular matrix may be provided as particles, a slurry, a paste, a gel, or in some other form. The acellular matrix may be provided as a three-dimensional scaffold that has been reconstituted from particles of the three-dimensional tissue. The three-dimensional scaffold may have the shape of an anatomical feature and serve as a template for tissue repair or replacement. A method of making an acellular soft tissue-derived matrix includes steps of removing lipid from the soft tissue by solvent extraction and chemical decellularization of the soft tissue.2015-02-05
20150037437GLIOMA TREATMENT - A chemotherapy agent or a pharmaceutical composition including chemotherapy agent and artificial cerebrospinal fluid, wherein the chemotherapy agent at a concentration of between 0.01 mg/ml and 0.7 mg/ml for use in the treatment of brain cancer and a method of treating a glioma including administering a chemotherapy agent via convection enhanced delivery2015-02-05
20150037438CHEWABLE GELLED EMULSIONS - An oral pharmaceutical composition in unit dose form, each unit dose comprising a lipophilic drug substance within a unitary carrier body, said body comprising a soft, chewable, gelled oil-in-water emulsion.2015-02-05
20150037439PHYTOGENIC NUTRACEUTICAL COMPOSITION AND METHODS OF USE THEREOF - A nutraceutical composition including as a functional ingredient an effective amount of a substance extracted from dry, fresh or ensilaged phytomass of genus 2015-02-05
20150037440METHOD FOR SUPPRESSING AND RELIEVING ITCHING AND INFLAMMATION - The present invention provides a method for suppressing and relieving itching and inflammation, by administering to a host in need of such treatment an effective amount of the pharmaceutical composition containing highly lipophilic polyalkoxyflavonoid. The pharmaceutical composition and functional food of the present invention for suppressing and relieving itching and inflammation contain highly lipophilic polyalkoxyflavonoid extracted from squeezed juice of a whole portion of a citrus fruit (inclusive of pericarp thereof). Furthermore, the functional food of the present invention contains it.2015-02-05
20150037441PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CONTAINING PHYLLOSTACHYS NIGRA MUNRO VAR HENOSIS STAPF EXTRACT AS ACTIVE INGREDIENT - The present invention relates to a method for treating chronic obstructive pulmonary disease (COPD) comprising the step of administering the extract of 2015-02-05
20150037442Composition to Enhance the Bioavailability of Curcumin - A composition having a curcuminoid and an essential oil of turmeric. A composition having a curcuminoid and an essential oil of turmeric, wherein the essential oil is present in an amount sufficient to cause an enhancement of bioavailability of curcumin when the composition is administered to a human as compared to bioavailability of curcumin obtained upon administration of a composition prepared without adding essential oil to the curcuminoid. A method to prepare a composition having a curcuminoid and an essential oil of turmeric.2015-02-05
20150037443RIGID CORE FOR FORMING TIRE - A rigid core for forming a tire is configured so that the non-uniformity of the amount of thermal expansion of the core body is reduced to improve the quality of the tire. The core body comprises divided core pieces (2015-02-05
20150037444PRESS ASSEMBLY AND COUPLING MECHANISMS FOR SAME - A press assembly for pressurising a body, comprising a frame and a cartridge for applying load to the body, in which the frame comprises a bore for accommodating the cartridge. The press assembly further comprises an axial securement mechanism for securing the cartridge axially within the bore and a radial securement mechanism for securing the cartridge radially within the bore. The press assembly is configured such that the cartridge can be rotated in the bore between a locked condition and an unlocked condition. The radial and axial securement mechanisms are cooperatively configured with respect to each other so when the cartridge is in the locked condition, both the radial and axial securement mechanisms are engaged and when the cartridge is in the unlocked condition the radial and axial securement mechanisms are both disengaged and there is a clearance gap between the cartridge and the bore permitting the cartridge to be axially displaceable within the bore.2015-02-05
20150037445AUTOMATED DEVICES, SYSTEMS, AND METHODS FOR THE FABRICATION OF TISSUE - Described herein are improvements to bioprinting technology that facilitate automation of tissue and organ fabrication processes.2015-02-05
20150037446FUSED FILAMENT FABRICATION SYSTEM AND METHOD - A fused filament fabrication system and method comprises a motor for moving the system along a linear rail during operation, a drive gear coupled to the motor. The drive gear rotates in the direction of the motor during operation and selectively operatively engages first or second idler gears during operation of the system. The system also comprises first and second filaments for the selective passage of material to corresponding first and second extruders, the first filament is positioned between the first idler gear shaft and idler bearing and the second filament is positioned between the second idler gear shaft and idler bearing.2015-02-05
20150037447EXTRUDER - An extruder having an operative unit having a cylinder and at least one extruder screw which is removably accommodated therein, a motor and a gear unit which is separated from the motor via a clutch and which drives the extruder screw, wherein the extruder screw is releasably connected to the gear unit, and a controller installation which controls the operation of the motor or at least of a further installation which is provided. The operative unit or is assigned to the operative unit, wherein at least one information element which identifies the extruder screw and which, during or after insertion of the extruder screw into the cylinder or connection to the gear unit, is automatically acquirable by a sensor element, is provided on the extruder screw, wherein the controller installation, depending on the acquired information, controls the operation of the motor or of the further installation.2015-02-05
20150037448FLOW OF HYDRAULIC FLUID FROM ACCUMULATOR ASSEMBLY AND FROM PUMP ASSEMBLY TO ACTUATOR WHERE HIGHER FLOW IS REQUIRED - A memory assembly (2015-02-05
20150037449MOLDING ELEMENT COMPRISING CUTTING MEANS FOR MOLDING AND VULCANIZING A TIRE TREAD - A molding element) of a mold for molding and vulcanizing a tire treadcontaining a molding surface intended to mold part of the tread surface of the tire and a complex blade of projecting from the molding surface, containing a body oriented mainly in a circumferential direction X and at least one U-shaped secondary branch facing towards this body, the secondary branch being oriented mainly in an oblique direction J, J making a non-zero angle ψ with a transverse direction Y perpendicular to the circumferential direction X, the secondary branch in contact with the main body at two contact zones to delimit a cavity of length L, wherein the molding element has a main cutting means projecting from the molding surface, extending between two of its ends and running parallel to J, the length being less than the length L, and wherein the molding element has at least two secondary cutting means of height Hs extending from one of the ends of the main cutting means as far as one of the contact zones facing this end, and forming an angle θ with this body.2015-02-05
20150037450HONEYCOMB EXTRUSION APPARATUS AND METHODS - A honeycomb extrusion apparatus includes first and second vanes with respective first and second face portions. First and second axial widths of a circumferential feed area are respectively defined between the first and second face portions and the outer feed surface of the die body. In further examples, methods include the steps of selectively adjusting the first axial width and the second axial width of the circumferential feed area by respectively adjusting the first and second vane relative to the mask. In further examples, a honeycomb extrusion apparatus includes a plurality of mask segments that each includes an inner peripheral surface portion. Each of the plurality of mask segments are independently adjustable along a respective radial axis.2015-02-05
20150037451SUPPORT PLATE DEVICE FOR BAKED GOODS - The support plate device for baked goods, pastries, or Viennese baked goods, includes at least one lower plate and at least two molds supported by the lower plate. The device further includes at least one upper plate, which covers the molds. The lower surface of the upper plate engages with the upper ends of the respective edges of the molds. There is a resilient return device for each mold, generating a force urging each mold individually and separately against the lower surface of the upper plate.2015-02-05
20150037452RESIN-RELEASING JIG - Provided are a resin-releasing jig including a base and a releasing layer formed on a surface side of the base, in which the releasing layer is composed of a resin containing a perfluorinated polymer as a main component, and the perfluorinated polymer is crosslinked; and the resin-releasing jig further including a primer layer disposed between the base and the releasing layer, in which the primer layer is composed of a resin containing, as a main component, a perfluorinated polymer and an engineering plastic, the perfluorinated polymer in the primer layer is crosslinked, and the releasing layer has high abrasion resistance and a good adhesive force to the base and thus the resin-releasing jig has good durability. In particular, provided is the resin-releasing jig which is an extrusion molding mold used in an extruder for producing a long resin molded article.2015-02-05
20150037453STRETCH BLOW MOLDING MACHINE WITH RAPID PROTOTYPING COMPONENTS - A method for producing a component for a blow molding module of a stretch blow molding machine which as a component to be produced includes at least one of a blow valve, a blow nozzle, a valve block, a stretching rod, a mold carrier, a shell mold one or more single- or multi-part mold inlay(s) with a container contour, and which entails that the component to be produced is completely or partly produced by use of an additive rapid prototyping method, for example by 3D printing or laser sintering, and is produced from one or more of metal, plastic materials, ceramic materials, or from a combination of metal, plastic materials and/or ceramic materials.2015-02-05
20150037454MOLD ASSEMBLY FOR FOMRING OPTICAL LENS FOR LED - A mold assembly for manufacturing an optical lens for LED, includes an upper die, an upper die core received in the upper die, a bottom die and a bottom die core received in the bottom die. The upper die core includes a bottom surface; the bottom surface has a profile corresponding to a profile of a top portion of the optical lens. The bottom die includes a base and a replaceable die core removably received in the base. The replaceable die core includes an upper surface, and the replaceable die core defines a chamber depressed downwardly at a center of the upper surface. A bottom portion of the optical lens is formed by in the chamber. The replaceable die core defines a plurality of fixing holes recessed downwardly from the chamber for forming positioning feet of the optical lens.2015-02-05
20150037455NUTRITIONAL COMPOSITIONS CONTAINING SYNERGISTIC COMBINATION AND USES THEREOF - A composition and method for enhancing brain development in a pediatric subject, the method including administering to the pediatric subject a nutritional composition having up to about 7 g/100 kcal of a fat or lipid source, wherein the fat or lipid source includes at least about 0.5 mg/100 kcal of milk or non-milk polar lipids; up to about 5 g/100 kcal of a protein source; at least about 15 mg/100 kcal of lactoferrin from a non-human source; about 0.015 g/100 kcal to about 0.15 g/100 kcal of a prebiotic composition including polydextrose and/or galactooligosaccharide; and at least about 5 mg/100 kcal of a source of long chain polyunsaturated fatty acids.2015-02-05
20150037456SYSTEM AND METHOD FOR DELIVERING HEALTH-PROMOTING SUBSTANCES INTO A HUMAN BODY - A system of delivering a health promoting substance into a human body that includes butter, water, milk protein concentrate, maltitol, erythritol, organic agave inulin, xanthan gum, locust bean gum, and guar gum ingredients at least one flavor ingredient; and a desired health promoting substance. The above ingredients, the flavor ingredient and the desired health promoting substance are formulated as a combined solidified frozen dessert for human consumption.2015-02-05
20150037457PROCESSES FOR PRODUCING LIPIDS - The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.2015-02-05
20150037458METHODS AND COMPOSITIONS FOR IMPROVING GROWTH OF MEAT-TYPE POULTRY - The present invention provides methods of improving growth performance, improving the efficiency of feed utilization, increasing feed digestibility, and decreasing mortality of immature and developing animals receiving animal feed. Methods of producing a crude keratinise enzyme extract and animal feed supplements for achieving the same are also provided.2015-02-05
20150037459Process for Reducing Ethanol Loss While Developing Desirable Organoleptics During Wooden Barrel Aging of Alcoholic Beverage - An alcoholic beverage is aged in a wooden barrel after the barrel is covered by a film having an oxygen transmission rate of at least 50 cc/m2015-02-05
20150037460DAIRY PRODUCT AND PROCESS - The invention process provides a novel process of making cheese comprising the production of a coagulum which is caused to disaggregate into small curd particles in an in-line continuous flow process, separation of the curd particles from the whey and subsequent heating and mechanical working of the curd particles into a cheese mass.2015-02-05
20150037461METHOD FOR PRODUCING FERMENTED MILK PRODUCT USING STERILE FULL-FAT SOYBEAN POWDER AS STARTING MATERIAL AND FERMENTED MILK PRODUCT - Provided are a production method for an edible fermented dairy product using, as a raw material, sterile full fat soy flour, which has a very high nutritional value and has a markedly improved taste evaluation that includes flavor and smooth texture, and a fermented dairy product produced by the method. A production method for a fermented dairy product includes the steps of: producing sterile full fat soy flour having a grain size of from 100 to 1,000 meshes by pulverizing sterile dehulled soybeans prepared so as to have a bacterial count of 300 cells/g or less by using a method of separating whole soybeans into cotyledons, germs, and hulls; adding water to the sterile full fat soy flour to prepare a powdered soy juice, followed by sterilizing the powdered soy juice by heating; homogenizing the powdered soy juice to prepare a homogenized powdered soy juice; and adding a lactic acid bacterium to the homogenized powdered soy juice, followed by fermentation to prepare fermented milk.2015-02-05
20150037462GLUCOSYL STEVIA COMPOSITION2015-02-05
20150037463MICRONIZED CaCO3 SLURRY INJECTION SYSTEM FOR THE REMINERALIZATION OF DESALINATED AND FRESH WATER - The present invention concerns a process for treating water and the use of calcium carbonate in such a process. In particular, the present invention is directed to a process for remineralization of water comprising the steps of (a) providing feed water having a concentration of carbon dioxide of at least 20 mg/l, preferably in a range of 25 to 100 mg/l, and more preferably in a range of 30 to 60 mg/l, (b) providing an aqueous slurry comprising micronized calcium carbonate, and (c) combining the feed water of step (a) and the aqueous slurry of step (b) in order to obtain remineralized water.2015-02-05
20150037464FAUCET-INTEGRATED CARBONATION SYSTEMS AND METHODS - Systems and methods are disclosed for providing carbonated water through a typical kitchen faucet. The faucet-integrated carbonation system can include a carbonated water reservoir coupled to a residential or commercial cold water supply line as well as a CO2015-02-05
20150037465Calcium-Fortified Beverages and Method of Making Thereof - A calcium-fortified beverage and method of making the beverage is provided. A calcium source is included that provides about 40% to about 65% of the calcium from calcium lactate and about 35% to about 60% of the calcium is provided from hydroxyapatite. A component may be included for at least substantially masking the aftertaste of the calcium source.2015-02-05
20150037466DOUBLE FORTIFIED SALT COMPOSITION CONTAINING IRON AND IODINE AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to stable and white iron fortification and iron+iodine double fortification agents, their preparation and use in fortification of salt. These agents help overcome the normal difficulties encountered in iron and iodine fortification such as low iodine stability on storage, development of colour and odour, and use of unwanted additives to impart stability. In one of the invented products, both iron and iodine coexist in stable manner in the same matrix which allow for a more uniform distribution of iodine. The process of preparation is demonstrated to be scalable and utilizes commonly available raw materials which would enable the products to be synthesized in affordable manner.2015-02-05
20150037467METHOD FOR MAKING POUCHES AND A POUCH AS SUCH - The present invention relates to a pouch and a method for making the same. In the inventive method, which is adapted to produce pouches having a limited amount of fusible material, a heat-sealable cord is arranged on a web forming confronting side surface of each pouch. Those confronting side surfaces are fused by heating the heat-sealable cord. The present invention furthermore provides a pouch, in particular containing a brewable or extractable commodity such as tea, with a pocket defined between confronting side surfaces of a web. The pouch of the present invention can have a limited amount of fusible material as the confronting side surfaces are joined by solidified melt of a heat-sealable cord arranged in vicinity of at least one edge of the pouch.2015-02-05
20150037468BAKERY PRODUCT AND METHOD OF PRODUCING A BAKERY PRODUCT - A bakery product and method of producing the same are provided. The bakery item includes a baked item having an underside, an upper side, and side surface. A first underside sub-region that extends over the entire width and part of the longitudinal extent of the underside is coated. A second underside sub-region that extends over the entire width and part of the longitudinal extent remains uncoated in the form of a grip region. The sub-region of the partial-coat underside which is to be coated is dipped into a bath of not yet set coating substance, which is set by cooling to form the coating. The underside of the baked item, which is to be coated, is oriented at an angle α between 1° and 20° in relation to the original surface of the bath at least during the setting operation.2015-02-05
20150037469HEALTHY BISCUIT - The disclosure concerns a method for producing a ready-to-eat biscuit comprising at least 29 wt % wholegrain cereal flour, 5 wt % to 22 wt % fat, and at most 30 wt % sugar relative to the total weight of the biscuit, wherein the slowly-digestible-starch-over-total-available-starch ratio of the biscuit is at least 31 wt %, the method comprising: mixing a cereal flour comprising the wholegrain cereal flour with fat and sugar and at most 8 wt % added water relative to the total weight of the dough, to form a dough; moulding the dough into the shape of a biscuit; baking the biscuit; wherein the cereal flour comprises refined cereal flour in an amount of at least 14.5 wt % of the dough and wherein the refined cereal flour has a water absorption under 55% as measured by Brabender® Farinograph® according to NF-ISO-5530-1 norm.2015-02-05
20150037470Capsule, Device and Method for Preparing a Beverage by Extraction - The invention relates to a capsule for use in a device for preparing beverages. The invention also relates to an assembly of such a capsule and a device for preparing beverages. The invention further relates to a method for preparing beverages by making use of such an assembly.2015-02-05
20150037471WIRELESS TEMPERATURE SENSING SYSTEM FOR A COOKING APPLIANCE - A temperature sensing system for a cooking appliance includes a control unit having a receiver. The control unit and the receiver are housed within the cooking appliance. The temperature sensing system further includes a wireless temperature sensing probe having a temperature sensor and a wireless transmitter module. The wireless temperature sensing probe is configured to wirelessly communicate with the control unit housed within the cooking appliance.2015-02-05
20150037472TEMPERATURE SENSING SYSTEM FOR A COOKING APPLIANCE - A temperature sensing system for a cooking appliance having an upper housing having a first heating surface and a lower housing having a second heating surface includes a temperature sensing probe, a control panel and a control unit in electrical communication with the temperature sensing probe and the control panel. The temperature sensing probe is removably received by the upper housing and extends through said first heating surface. The control panel has one or more input buttons for allowing a user to select at least one input parameter including a desired internal temperature of a food item.2015-02-05
20150037473METHOD AND SYSTEM FOR DETERMINING THE CONSUMPTION BY AN INFANT OF BEVERAGES PRODUCED FROM CAPSULES IN A BEVERAGE PRODUCTION MACHINE - A system and method for determining the consumption by an infant of beverages produced from capsules in a beverage production machine. Capsule information regarding a plurality of different types of capsules is stored in a server. Further at least one user account including personal information about the infant consuming beverage produced from capsules is stored in said server. A beverage is produced from a capsule and the capsule used therefore by the beverage production machine is identified. The information on the identified capsule is transmitted to the server; such information including at least the date and time the beverage is prepared.2015-02-05
20150037474Prepared Dough for Baked Goods with Novel Organoleptic Properties - The present invention discloses a novel method of creating dough for baked goods, particularly cookies, featuring small amounts of flavoring and texturing additive mixed for an extended period of time with other ingredients such that novel organoleptic properties (flavor and texture or “mouthfeel”) are imparted to the baked goods created from the dough.2015-02-05
20150037475BUTCHERING PROCESSES FOR MEAT PRODUCTS - A method for mass-production butchering of a chuck roll of beef includes: sectioning the chuck roll anterior to and generally parallel to the first rib to separate a neck portion thereof from a remainder thereof; sectioning the remainder into a first portion and a second portion substantially along a natural seam, the first portion comprising rhomboideus, spinalis dorsi, and serratus ventralis muscles, and the second portion comprising multifidus dorsi, complexus, and longissimus dorsi muscles; sectioning the first portion to substantially remove the rhomboideus and the spinalis dorsi therefrom, leaving a denuded serratus ventralis; sectioning the serratus ventralis into a first set of separate portions. The method may further include: sectioning the second portion into a second set of separate portions, each separate portion in the second set including the multifidus dorsi, complexus, and longissimus dorsi muscles.2015-02-05
20150037476USE OF PHOTOSYNTHETIC PIGMENT STABILIZING AGENTS TO REGULATE RIPENING AND QUALITY IN FRUITS AND VEGETABLES - Methods and compositions to temporarily delay the ripening, maturation, senescence and pathogen infection of produce such as fruits, vegetables and ornamental plants are provided. The methods involve the application of a photosynthetic pigment and/or membrane stabilizing chemical (e.g. glycine betaine) to produce which is identified as in need of such delay. Application may be prior to harvest, at or during harvest or post-harvest.2015-02-05
20150037477VACUUM STORAGE APPARATUS WITH SLIDING DRAWERS - Provided is a modular vacuum storage apparatus and method for storing, dispensing, preserving and shipping perishable items.2015-02-05
20150037478METHOD AND DEVICE FOR DRYING INSTANT NOODLES - An object of the present invention is to provide a method for drying non-fried noodles for obtaining non-fried noodles that are easily loosened without sticking of noodle strings and excellent in restorability. The present invention includes, as a step of drying non-fried noodles, a step of putting gelatinized noodle strings into a retainer, the retainer having one or more small holes in a bottom surface thereof so as to give a ratio of the total area of the small holes to the area of the bottom surface of the retainer of 30% or less, or having no small hole in the bottom surface, that is, the retainer having an aperture ratio of 0 to 30% and blowing a high-speed air flow, preferably having a wind speed of 50 m/s or higher, from above the retainer toward the noodle strings in the retainer.2015-02-05
20150037479WINE AERATING DEVICES AND METHODS OF AERATING WINE - Wine aerating devices and methods of aerating wine are disclosed. A wine aerating device can include an actuator, a piston movable between first and second positions, a pumping chamber coupled to the piston, and a bubble generating material coupled to the pumping chamber. Upon application and release of a force on the actuator, the piston can move between the first and second positions to inject a metered amount of air from the pumping chamber out through the bubble generating material to generate air bubbles into a container of wine.2015-02-05
20150037480Food Processor with Locking Bail Handle - A kitchen appliance for processing foodstuff comprises a housing, a bowl, a bowl lid, and a bail handle. The bowl is removably mountable onto the housing and comprises an upper rim defining a mouth for selectively receiving a rotatable tool within the bowl. The bowl lid is removably mountable onto the upper rim of the bowl and comprises a top wall and a flange depending downwardly therefrom. The bail handle is pivotably affixed to opposing sides of the housing. The bail handle is pivotable between (1) a disengaged position in which the bowl lid may be removed from the bowl and in which the bowl may be removed from the housing and (2) an engaged position in which the bail handle applies downward pressure on the bowl lid to retain the bowl lid on the upper rim of the bowl and to retain the bowl on the housing.2015-02-05
20150037481FOOD PREPARATION DEVICE AND METHOD OF PREPARING FOOD - Methods and apparatuses for mixing food are disclosed. In an embodiment, a mixing device includes a housing including a cavity configured to hold an item and at least one cord attached to the housing. The at least one cord is configured to cause the housing to rotate when the at least one cord is pulled in a direction away from the housing. In another embodiment, a method of mixing includes placing an item inside of a housing, rotating the housing in a first direction to create tension, and releasing the tension so that the housing rotates in a second direction and mixes the item.2015-02-05
20150037482TEMPERATURE SENSING AND CONTROL SYSTEM FOR A COOKING APPLIANCE - A cooking appliance includes an upper housing having a first heating plate, a lower housing having a second heating plate, and a temperature probe extending through one of the first heating plate and the second heating plate for detecting an internal temperature of a food item.2015-02-05
20150037483DEVICE AND METHOD FOR THE CONDENSATION OF A VAPOR IN A VACUUM CHAMBER - A vacuum cooling device for the cooling of foodstuff, in particular hot bakery products comprises a vacuum chamber (2015-02-05
20150037484Methods and Compositions Related to French Fry Dough and Products Thereof - Disclosed herein include embodiments related to an ultra-high surface area French Fry product extruded from dough by a device and requiring a fraction of the cooking time compared with standard French fries, as well as producing a French Fry product that is crispier than standard French fries.2015-02-05
20150037485REDUCED SATURATED AND TOTAL FAT CONTENT PIE CRUSTS - The application relates to a composition comprising from about 2% (w/w) to about 4% (w/w) alkenyl succinic anhydride substituted starch, from about 3% (w/w) to about 8% (w/w) heat-moisture treated wheat flour, from about 5% (w/w) to about 7% (w/w) vegetable oil, and from about 78% (w/w) to about 87% (w/w) of other conventional baking ingredients.2015-02-05
20150037486OIL/FAT COMPOSITION - Provided is a fat or oil composition having high oxidative stability even though containing a large amount of α-linolenic acid, and having suppressed degradation odor and unpleasant odor derived from a rosemary extract at the time of cooking. The fat or oil composition comprises the following components (A), (B), and (C): (A) a fat or oil comprising constituent fatty acids comprising from 15 to 60 mass % of α-linolenic acid; (B) from 0.001 to 0.18 mass % of a rosemary extract; and (C) a dill extract, in which a mass ratio of a content of the component (B) to a content of the component (C), [(B)/(C)], is from 2 to 200.2015-02-05
20150037487FEATHER BASED COMESTIBLE COMPOSITIONS AND METHODS FOR MAKING SUCH COMPOSITIONS - The invention provides methods for making a comestible compositions by producing a mixture comprising from about 20 to about 60% feather, from about 30 to about 65% polyol and from about 0.1 to about 3% feather degradation agent; and heating the mixture to a temperature of from about 120 to about 240° C. under a pressure of from, about 200 to about 1000 psi for a period of from about 2 to about 10 minutes. The invention also provides comestible compositions produced by the methods.2015-02-05
20150037488METHOD FOR THE PRODUCTION OF AN EXPANDED AND DEHYDRATED PROTEIN FOOD - A method for the production of an edible expanded dehydrated protein product which comprise submitting the pork skin pellets to a high temperature and pressure inside a sealed chamber and later to a sudden decompression in order to cause the instantaneous evaporation of the water in the pellet and produce a pork crackling having a fat content very similar to the original pellet, which is substantially lower than in the pork crackling produced by traditional methods.2015-02-05
20150037489BUTCHERING PROCESSES FOR MEAT PRODUCTS - A method for mass-production butchering of a beef chuck roll includes locating an anterior side and a posterior side of the chuck roll, and making a first series of cuts into the chuck roll along lines not intersecting the anterior and posterior sides. The first series of cuts form a first set of separate beef portions with increasing weights from initial to final cuts in the first series. The method also includes making a second series of cuts into the chuck roll along lines not intersecting the anterior and posterior sides to form a second set of separate beef portions.2015-02-05
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