06th week of 2009 patent applcation highlights part 43 |
Patent application number | Title | Published |
20090035666 | CONTAINER FOR HOUSING A MASK BLANK, METHOD OF HOUSING A MASK BLANK, AND MASK BLANK PACKAGE - A container is adapted to receive a mask blank having a resist film and includes a container body having an upper opening and a cap put on the container body. The container body has an opening edge provided with an annular elastic member made of polyolefin elastomer or the like and extending throughout entire circumference. When the cap is put on the container body, the elastic member is interposed at a joint portion between the cap and the container body to hermetically seal the container. | 2009-02-05 |
20090035667 | Method for correcting mask - There is provided a method for correcting a photo mask, which allows the difference between a test mask and a corrected mask with respect to an error of line width depending on coarse/dense pattern to be decreased when the photo masks are corrected by optical proximity effect correction. | 2009-02-05 |
20090035668 | Method and materials for patterning a neutral surface - A self assembly step for the manufacture of an electronic component comprising, e.g., a semiconductor chip or semiconductor array or wafer comprises forming a diblock copolymer film placed on a random copolymer film substrate operatively associated with the electronic component and the diblock copolymer film wherein the surface energy of the random copolymer film is tailored by use of a photolithographic process prior to the self assembly step. By prior deterministic control over regional surface properties of the random copolymer film, domains of the diblock copolymer film form only in predefined areas. This approach offers simplified processing and a precise control of regions where domain formation occurs. Selective removal of some of the domains allows for further processing of the electronic component. | 2009-02-05 |
20090035669 | WORK POSITION INFORMATION OBTAINING METHOD AND APPARATUS - A work position information obtaining apparatus capable of obtaining a position of a work with respect to a table with high accuracy. Moving a table with a work placed thereon relative to an imaging section. Obtaining work position information representing a position of the work with respect to the table based on imaged information obtained by imaging table and work reference marks by the imaging section and moving direction positions of the table at the time of imaging the table and work reference marks. Obtaining the positional deviations of the table at the time of imaging the table and work reference marks, with reference to a positional deviation of the table obtained in advance in association with each of the moving direction positions of the table. Then, eliminating an error included in the work position information arising from the difference between each imaged positional deviation. | 2009-02-05 |
20090035670 | Hard imaging methods, liquid marking agent monitoring methods, and hard imaging devices - Hard Imaging Methods, Liquid Marking Agent Monitoring Methods, and Hard Imaging Devices are described. According to one embodiment, a hard imaging method includes forming a plurality of latent images using a hard imaging device, using the hard imaging device, developing the latent images using a liquid marking agent, wherein bubbles are present in the liquid marking agent during the developing, calibrating the hard imaging device, and reducing bubbles present in the liquid marking agent during the calibrating compared with the bubbles present in the liquid marking agent during the developing. Additional embodiments are described in the disclosure. | 2009-02-05 |
20090035671 | ADJUSTMENT METHOD, EXPOSURE METHOD, DEVICE MANUFACTURING METHOD, AND EXPOSURE APPARATUS - An adjustment method for adjusting an illumination condition in illuminating an original plate using an illumination optical system and projecting an image of a pattern formed on the original plate onto a substrate through a projection optical system includes measuring a polarization state of light that has passed through the illumination optical system, the original plate, and the projection optical system in a state where the original plate is located on an object plane of the projection optical system, and adjusting the polarization state based on the measured polarization state. | 2009-02-05 |
20090035672 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING PHOTOCONDUCTOR, AND PROCESS CARTRIDGE - To provide an electrophotographic photoconductor that comprises a support and a cross-linked layer formed over the support, wherein the cross-linked layer comprises at least light curable of radically polymerizable compound, the difference of maximum value of the post-exposure electrical potential and minimum value of the post-exposure electrical potential when writing is conducted under the condition that image static power is 0.53 mW, exposure energy is 4.0 erg/cm | 2009-02-05 |
20090035673 | IRON CONTAINING HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS - A photoconductor that includes a substrate; an undercoat layer thereover wherein the undercoat layer contains, for example, a metal oxide, and an iron containing compound; a photogenerating layer; and at least one charge transport layer. | 2009-02-05 |
20090035674 | UV ABSORBING HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS - A photoconductor that includes a substrate; an undercoat layer thereover comprised of a metal oxide, and an ultraviolet light absorber component; a photogenerating layer; and at least one charge transport layer. | 2009-02-05 |
20090035675 | COPPER CONTAINING HOLE BLOCKING LAYER PHOTOCONDUCTORS - A photoconductor that includes, for example, a substrate; an undercoat layer thereover wherein the undercoat layer contains a metal oxide, and a copper containing compound; a photogenerating layer; and at least one charge transport layer. | 2009-02-05 |
20090035676 | IODONIUM HOLE BLOCKING LAYER PHOTOCONDUCTORS - A photoconductor that includes, for example, a substrate; an undercoat layer thereover wherein the undercoat layer contains a metal oxide and an iodonium containing compound; a photogenerating layer; and at least one charge transport layer. | 2009-02-05 |
20090035677 | CONDENSATION POLYMER PHOTOCONDUCTIVE ELEMENTS - The present invention relates to photoconductive elements having an electrically conductive support, an electrical barrier layer and, disposed over the conductive layer, a charge generation layer capable of generating positive charge carriers when exposed to actinic radiation. The electrical barrier layer, which restrains injection of positive charge carriers from the conductive support, comprises a crosslinkable condensation polymer having as a repeating unit a planar, electron-deficient, tetracarbonylbisimide group and optionally a crosslinker, | 2009-02-05 |
20090035678 | MIXED CYCLIC PHENOL SULFIDES, AND CHARGE CONTROL AGENTS AND TONERS USING THE SAME - The present invention discloses a mixed cyclic phenol sulfide which is a mixture of the cyclic phenol sulfide wherein m is 8 and the cyclic phenol sulfide wherein m is an integer other than 8, the cyclic phenol sulfide being represented by the following formula (1): | 2009-02-05 |
20090035679 | MAGNETIC TONER - A magnetic toner is disclosed having magnetic toner particles containing a binder resin and a magnetic iron oxide. The magnetic toner has a specific saturation magnetization and a specific residual magnetization in ascertain magnetic field. The binder resin includes a polyester component polymerized with an aromatic carboxylic acid titanium compound as a catalyst. | 2009-02-05 |
20090035680 | POSITIVE CHARGE CONTROLLING AGENT, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC TONER CONTAINING THE SAME - Provided are a positive charge controlling agent which is excellent in compatibility with and dispersibility in a binder resin, prevented from discoloring, excellent in chargeability, and reduced in the content of organic compounds having low boiling points, thereby giving no strong odor; a process for producing the same; and an electrophotographic toner which exhibits excellent chargeability and colorability, and the controlled production of VOC. The positive charge controlling agent includes a copolymer obtained by copolymerizing a styrene monomer (M1), a (meth)acrylic acid alkyl ester monomer (M2), and a quaternary ammonium salt (M3) of a dialkylaminoalkyl(meth)acrylate monomer, wherein a copolymerizing ratio (mass %) of the monomers, (M1)+(M2):(M3), is 99.5:0.5 to 65:35, and at least one end thereof is RCOO— or RO—, where R is an alkyl group, an aryl group, an aralkyl group, or an alicyclic group. | 2009-02-05 |
20090035681 | TONER, PROCESS FOR PRODUCING TONER, AND TWO-COMPONENT DEVELOPING AGENT - A toner or two-component developer is obtained by mixing, aggregating, and heating resin particles, colorant particles, and wax particles in an aqueous medium. A gel permeation chromatography (GPC) measurement of the resin particles shows that a weight-average molecular weight is 10000 to 60000, and the ratio of the weight-average molecular weight to a number-average molecular weight is 1.5 to 6. The wax particles include at least a first wax and a second wax. An endothermic peak temperature (melting point Tmw | 2009-02-05 |
20090035682 | TONER AND PROCESS FOR PRODUCING THE SAME - A toner of the present invention includes a first wax and a second wax. The endothermic peak temperature of the first wax by the DSC method is 50° C. to 90° C. The endothermic peak temperature of the second wax is 5° C. to 50° C. higher than that of the first wax. Jmw | 2009-02-05 |
20090035683 | TONER, TWO-COMPONENT DEVELOPER AND IMAGE FORMATION DEVICE - A toner comprising a small-particle diameter external additive having a number average particle diameter of 7 to 20 nm, a large-particle diameter external additive having a number average particle diameter of 40 to 80 nm and a toner particle having a volume average particle diameter of 4 to 7 μm, wherein the large-particle diameter external additive is stuck to the surface of the toner particles in a semi-embedded state and has a rate of liberation of 0.1% by weight or less from the surface of the toner particle. | 2009-02-05 |
20090035684 | IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD - An image forming method is disclosed, which includes steps of cleaning toner remaining on a photoreceptor surface by a cleaning blade which is arranged on counter direction to rotation direction of the photoreceptor, supplying a fatty acid metal salt onto the photoreceptor surface after the cleaning, spreading the supplied fatty acid metal salt on the photoreceptor surface by using a spreading blade which is arranged on trail direction to rotation direction of the photoreceptor, charging the photoreceptor by a charging member, exposing the photoreceptor to form a latent image, developing the latent image by a developer to form a toner image on the photoreceptor, and transferring the toner image onto an image receiving member by a transfer roller facing to the photoreceptor through the image receiving material, in which the toner comprises a binder resin and a colorant, in which the toner has a glass transition point of from 20 to 45° C. and the binder resin contains 50% or more of vinyl polymer resin by weight based on the whole weight of the binder resin. | 2009-02-05 |
20090035685 | COLOR TONER - The color toner has capsule type toner particles each having a surface layer (B) mainly formed of a resin (b) on the surface of a toner base particle (A) containing at least a binder resin (a), a colorant, and a wax, in which (1) a temperature Tp at which a curve | 2009-02-05 |
20090035686 | CORE-SHELL POLYMER NANOPARTICLES AND METHOD OF MAKING EMULSION AGGREGATION PARTICLES USING SAME - Nano-sized particles for use in making emulsion aggregation toner particles have a core portion and a shell portion, wherein the core portion of the nano-sized particles includes crystalline resin and the shell portion includes amorphous resin and is substantially to completely free of the crystalline resin. | 2009-02-05 |
20090035687 | Colored Particles and Manufacturing Method Thereof - Colored particles and their manufacturing method are disclosed. Each of the colored particles composed of a core shell structure comprising a core particle and a colored shell layer formed on a surface of the core particle; and the core particle is composed of a hydrophobic resin; the colored shell layer comprises an active agent structure resin having a hydrophobic part and a hydrophilic part, and a colorant particle; a volume based median particle diameter of the colored particles is 2 to 100 μm; and
| 2009-02-05 |
20090035688 | TONER, AND TONER PRODUCTION PROCESS - In a chart of molecular weight distribution measured of a toner, i) the toner has a main peak in the region of molecular weight of 16,000 to 60,000, and ii) where the molecular weight at the main peak is represented by M1, and where the height at the molecular weight M1 is represented by H(M1), the height at a molecular weight of 4,000 by H(4000) and the height at a molecular weight of 15,000 by H(15000), the H(4000), the H(15000) and the H(M1) satisfy a specific proportion. The toner has a weight-average molecular weight (Mw) of 15,000 to 80,000, and, in an endothermic chart, i) the toner has an endothermic main peak in the range of 40 to 1300C, and ii) the calorimetric integral value represented by the peak area of the endothermic main peak is 10 to 35 J per 1 g of the toner. | 2009-02-05 |
20090035689 | Treatment For Enhancing Crack Resistance Of Organic Photoconductors - A method of treating a photoconductor for enhancing crack resistance when it comes into contact with a liquid toner comprises bending a photoconductor sheet having a length and a width to a tube having an outer diameter and a length corresponding to the width of the photoconductor sheet with the photoconductive layer facing outward. The tube of the photoconductor sheet is then inserted into a cylinder having an inner diameter greater than the outer diameter of the tube and a length of at least the length of the tube of the photoconductor sheet. The treatment of the tube of the photoconductor sheet in the cylinder takes place by maintaining it in the cylinder at a temperature of from about room temperature to an elevated temperature. The tube of the photoconductor sheet, is removed from the cylinder while it is at about room temperature. | 2009-02-05 |
20090035690 | PRINTING SYSTEM, PROCESS, AND PRODUCT WITH MICROPRINTING - The invention relates to printing of documents, for example bank checks. According to the various aspects of the invention, a printing system, process and product with microprinting are provided. Documents printed as described may include digitally variable microprint and other enhancements. The invention is particularly useful for enhanced security documents and the production thereof. | 2009-02-05 |
20090035691 | POSITIVE RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND COMPOUND - A positive resist composition that includes a base material component (A) that contains an acid-dissociable, dissolution-inhibiting group and exhibits increased alkali solubility under the action of acid, and an acid generator component (B) that generates acid upon exposure, wherein the base material component (A) contains a compound (A | 2009-02-05 |
20090035692 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING MEHTOD - A positive resist composition, includes: (A) a compound capable of generating an acid upon irradiation with actinic rays or radiation; (B) a resin of which solubility in an alkali developer increases under an action of an acid; (C) a compound capable of decomposing under an action of an acid to generate an acid; and (D) a compound which itself acts as a base for the acids generated from the component (A) and the component (C) but decomposes upon irradiation with actinic rays or radiation to lose a basicity for the acids generated from the component (A) and the component (C). | 2009-02-05 |
20090035693 | PHOTOSENSITIVE RESIN COMPOSITION, PRODUCTION METHOD FOR CURED RELIEF PATTERN USING IT, AND SEMICONDUCTOR DEVICE - According to the present invention, there is provided: a photosensitive resin composition comprising a polyamide resin having a specific structure, a photosensitive agent, and a compound having at least two sulfonate ester groups; a production method for a cured relief pattern using the photosensitive resin composition; and a semiconductor device containing the cured relief pattern formed according to the production method. | 2009-02-05 |
20090035694 | POLYMERIC DYES, OVERCOAT COMPOSITIONS AND THERMAL LITHOGRAPHIC PRINTING PLATES - A thermal lithographic printing plate overcoat composition comprising (a) a water-soluble polymeric dye having an absorption band between about 300 and about 600 nm; and (b) micro-particles or nano-particles is provided. A negative-working thermal lithographic printing plate comprising (a) a hydrophilic substrate; (b) a near infrared imaging layer disposed on the hydrophilic substrate; and (c) an overcoat layer disposed on the imaging layer, said overcoat layer comprising a water-soluble polymeric dye having an absorption band between about 300 and about 600 nm; and micro-particles or nano-particles is also provided. Finally, a water-soluble polymeric dye having an absorption band between about 300 and about 600 nm is provided. | 2009-02-05 |
20090035695 | POSITIVE WORKING LITHOGRAPHIC PRINTING PLATES - A positive-working lithographic printing plate precursor is disclosed comprising on a grained and anodized aluminum support having a hydrophilic surface or which is provided with hydrophilic layer, a coating comprising:
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20090035696 | PHOTORESIST COMPOSITION - Disclosed are a photoresist composition characterized by containing a polymer (A) containing a carboxyl group or a hydroxyl group, a polyfunctional alkenyl ether (B) represented by the general formula (I) below, and a photoacid generator (C) and the like. (In the formula, R | 2009-02-05 |
20090035697 | NEGATIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN - A chemically amplified negative resist composition is provided in addition to a method of forming a resist pattern from which a desirable pattern shape can be obtained. A negative resist composition in which a resin component (A) contains a resin component (A1) having a structural unit (a1) containing an alicyclic group having a fluorinated hydroxyalkyl group and a structural unit (a2) derived from an acrylic acid ester and containing a hydroxyl group-containing alicyclic group; and an acid generator component (B) contains an acid generator (B1) expressed by the following general formula (B1): | 2009-02-05 |
20090035698 | POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING METHOD - The present invention is a positive resist composition and a resist pattern forming method including a resin component (A) which has a polymer compound (A1) having a structural units (a1) including an acetal type acid dissociable, dissolution inhibiting group, a structural unit (a2) derived from an acrylate ester having a lactone-containing polycyclic group, and a structural unit (a3) derived from an acrylate ester having a polar group-containing aliphatic hydrocarbon group, and an acid generator component (B) having an onium salt-based acid generator (B1) having a cation portion represented by a general formula (b-1) shown below | 2009-02-05 |
20090035699 | FLUORINATED MONOMER, FLUORINATED POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS - Fluorinated monomers of formula (1) are useful in producing polymers for the formulation of radiation-sensitive resist compositions. R | 2009-02-05 |
20090035700 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION - (1) A polymer compound for photoresist compositions which is high in storage stability and small swelling at the development and (2) a compound which is a raw material for such a polymer compound are provided; and (3) a photoresist composition with improved LWR containing the subject polymer compound are further provided. In detail, [1] a tertiary alcohol derivative represented by the following general formula (1) is provided. | 2009-02-05 |
20090035701 | Photoresist and pattern-forming process using the same - A photolithography process using a photoresist is as following. A substrate is provided for coating a photoresist thereon to form a photoresist layer and the photoresist is formed by mixing photocatalyst particles and polymer binder in a solvent. The photoresist layer is well-adhesive and has good mechanical strength. A light is illuminated on the photoresist layer through a photo mask having a pre-designed pattern thereon. Then, the portion of the photoresist layer where the light projects is removed by water or another environment-friendly solvent so as to reduce the harmful waste produced in the processes. | 2009-02-05 |
20090035702 | PROCESS FOR PRODUCING COMPOUND HAVING ACID-LABILE GROUP - The present invention provides a process for producing a compound having a group represented by general formula (II): | 2009-02-05 |
20090035703 | Regeneratable, structured plate comprising oxidation catalysts - A regeneratable plate having a structured surface comprising hydrophilic and hydrophobic regions. The plate comprises a substrate, a first layer comprising a hydrophilic oxidation catalyst arranged on the substrate, and a second layer which is hydrophobic and is imagewise arranged on the first layer to thereby afford the structured surface comprising hydrophobic regions and hydrophilic regions. A process for making the plate by imagewise exposure is also described. | 2009-02-05 |
20090035704 | Underlayer Coating Composition Based on a Crosslinkable Polymer - The present invention relates to an underlayer coating composition capable of being crosslinked comprising a polymer, a compound capable of generating a strong acid, and optionally a crosslinker, where the polymer comprises at least one absorbing chromophore and at least one moiety selected from an epoxy group, an aliphatic hydroxy group and mixtures thereof. | 2009-02-05 |
20090035705 | METHOD OF FORMING PATTERN, METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, AND CLEANING APPARATUS - A method of forming a pattern includes forming a resist layer on a substrate, cleaning a surface of the substrate under a control that a shear stress acting on an interface between a cleaning liquid and the substrate during the cleaning becomes larger than a shear stress acting on an interface between an immersion liquid and the substrate during immersion exposure, exposing the resist layer by the immersion exposure to form a latent image on the resist layer, and developing the resist layer to form a resist pattern on the substrate. | 2009-02-05 |
20090035706 | Method for Fabricating Micromachine Component of Resin - A method for fabricating a micromachine component of resin comprising step (a) of forming a sacrifice layer on a substrate, step (b) of forming at least two photosensitive resin composition layers sequentially on the sacrifice layer, and performing photolithography of each photosensitive resin composition layer to form an air gap portion defining the circumferential edge potion of the micromachine component and an air gap portion where an internal structure of the micromachine component is constituted to form a multilayer structure, step (c) for depositing dry film resist on the multilayer structure of the cured photosensitive resin composition layer, and performing photolithography of the dry film resist layer to form a cured dry film resist layer in which an air gap portion defining the circumferential edge of a shroud layer and an air gap where the structure of the shroud layer is constituted are formed, and step (d) for separating the micromachine component having the multilayer structure of the cured photosensitive resin composition layer and the cured dry film resist layer from the substrate by removing the sacrifice layer. | 2009-02-05 |
20090035707 | RHEOLOGY-CONTROLLED CONDUCTIVE MATERIALS, METHODS OF PRODUCTION AND USES THEREOF - Compositions comprising at least one conductive nanomaterial and at least one rheology control additive are disclosed. These compositions can be used to form a film for uses requiring sufficient conductivity and light transparency. Methods of forming a conductive composition include: providing at least one conductive nanomaterial, providing at least one rheology control additive, and blending the at least one conductive nanomaterial and the at least one rheology control additive together to form the conductive composition. Methods of forming patterned transparent conductive coatings include: providing and applying a layer comprising at least one photosensitive or photoimageable composition to a surface, providing and applying a layer comprising at least one conductive nanomaterial and at least one rheology control additive, exposing and developing the layered material, and treating the layer comprising the at least one rheology control additive in order to remove at least part of the rheology control additive. Coating compositions, films, patterned films and structures containing these films and patterned films are also described. | 2009-02-05 |
20090035708 | LAYER PATTERNING USING DOUBLE EXPOSURE PROCESSES IN A SINGLE PHOTORESIST LAYER - A structure and a method for forming the same. The method includes providing a structure which includes (a) a to-be-patterned layer, (b) a photoresist layer on top of the to-be-patterned layer wherein the photoresist layer includes a first opening, and (c) a cap region on side walls of the first opening. A first top surface of the to-be-patterned layer is exposed to a surrounding ambient through the first opening. The method further includes performing a first lithography process resulting in a second opening in the photoresist layer. The second opening is different from the first opening. A second top surface of the to-be-patterned layer is exposed to a surrounding ambient through the second opening. | 2009-02-05 |
20090035709 | Gas combustion apparatus - Apparatus is described for combusting exhaust gases output from a plurality of process chambers. The apparatus comprises a plurality of exhaust gas combustion nozzles ( | 2009-02-05 |
20090035710 | Automatic device for the ignition and control of a gas apparatus and relative driving method - Automatic device for the ignition and control of a gas apparatus comprising at least one burner for regulating the flow of gas from a main pipe towards a nozzle associated with the burner;
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20090035711 | PHOTOCATALYTIC IGNITION SYSTEM - A photocatalytic ignition system is provided that basically comprises an ignition chamber, a photocatalyst and a light source. The ignition chamber is configured to receive an air fuel mixture. The photocatalyst is arranged in the ignition chamber to contact an air fuel mixture. The light source is arranged to shine light on the photocatalyst. The photocatalyst includes a photocatalytic material having an oxygen absorbing and a desorbing function. The photocatalytic ignition system is capable of igniting a lean air fuel mixture with a greatly reduced amount of light energy. | 2009-02-05 |
20090035712 | Reheat Furnace System with Reduced Nitrogen Oxides Emissions - A reheat furnace system and heating process is provided. A hydrocarbon fuel and steam mix is supplied to a chemical recuperator that uses heat from the waste gas of the reheat furnace to produce preheated reformed fuel to the burners of the reheat furnace. The steam may be supplied from a waste heat boiler. | 2009-02-05 |
20090035713 | REHEAT AND TUNNEL FURNACE SYSTEMS WITH REDUCED NITROGEN OXIDES EMISSIONS - A reheat and tunnel furnace system, and heating processes therefor, are provided. A hydrocarbon fuel and steam mix is supplied to a chemical recuperator that uses heat from the waste gas of the reheat or tunnel furnace to produce preheated reformed fuel to the burners of the reheat or tunnel furnace. The steam may be supplied from a waste heat boiler. | 2009-02-05 |
20090035714 | Methods and systems for concurrent tooth repositioning and substance delivery - The present invention provides devices, systems and methods for orthodontic treatment using elastic repositioning appliances while concurrently providing dental and periodontal therapies. Such therapies are traditionally provided with the use of a variety of accessories and devices which are applied when the repositioning appliance is removed from the patient's mouth. The present invention eliminates the need for such removal and additional devices by incorporating these therapies into the repositioning appliance. | 2009-02-05 |
20090035715 | ORTHODONTIC ATTACHMENT MODULE FOR INTRA-ORAL BITE CORRECTORS - A module for attaching an orthodontic bite corrector to an orthodontic buccal tube appliance includes two segments, and each segment includes a rotation stop for limiting undesired rotational movement of bite corrector during movement of the patient's jaws. The segments are movable relative to each other during installation of the attachment module for facilitating placement of the rotation stops in regions next to the buccal tube appliance that might otherwise be difficult to access. | 2009-02-05 |
20090035716 | METHODS AND APPARATUS TO POSITION AND ALIGN TEETH USING AN EXO-SHELL - Methods and related apparatus for positioning and aligning any portion of the dento-facial region of a person. In one embodiment the method includes (a) providing or measuring any aspect of one or more alignment appliances to a person; (b) casting a shadow or making a mark on one or more areas of the dento-facial region of the person or the one or more alignment appliances in close proximity to one or more areas of the dento-facial region of the person with one or more light sources or marking devices; (c) measuring and analyzing data regarding one or more of the size, shape, length, and position of the one or more shadows or marks relative to other shadows or marks, one or more areas of the dento-facial region of the person or the one or more alignment appliances to obtain data; and (e) adjusting or replacing the alignment appliance or modifying the dento-facial alignment treatment plan of the person to align one or more areas of the dento-facial region of the person. | 2009-02-05 |
20090035717 | Electromagnetic radiation emitting toothbrush and transparent dentifrice system - A cleaning and whitening system for teeth having an electromagnetic radiation emitting toothbrush and a dentifrice with a photosensitive agent is disclosed. The toothbrush has a cleaning surface, such as bristles. The toothbrush is also adapted to direct electromagnetic radiation toward the cleaning surface. The electromagnetic radiation may be monochromatic or polychromatic. Further, the electromagnetic radiation may be substantially free of ultraviolet radiation. Additionally, the electromagnetic radiation may consist essentially of wavelengths within a range of 300 to 750 nanometers. The photosensitive agent is dispersed throughout the dentifrice. The dentifrice transmits the electromagnetic radiation through a varying thickness disposed over a target surface during use of the system. As a result, a significant portion of the photosensitive agent reacts, resulting in whitening stains, removing and/or disclosing undesired substances, and/or foaming. The dentifrice may be clear and may have clear abrasive particles. A method for tuning the cleaning and whitening system for teeth includes formulating the dentifrice with photosensitive agents that react to a range of electromagnetic radiation and providing a toothbrush that emits that electromagnetic radiation range. Another method of tuning the cleaning and whitening system includes designing a toothbrush that emits a range of electromagnetic radiation and formulating a dentifrice with photosensitive agents that react to the electromagnetic radiation range. | 2009-02-05 |
20090035718 | DENTAL ISOLATION BLOCK - A dental isolation block adapted for maintaining the mouth of the dental patient open, while keeping the work field dry and exposed with the lip retracted and the tongue suppressed to facilitate performance of a dental procedure by a dental practitioner. The dental isolation block includes a first and second bite platform capable of being disposed between the maxillary arch and mandibular arch, a lip retractor with a first end adjacent the first bite platform and a second end adjacent the second bite platform, and a tongue shield extending between the first and second bite platform. The lip retractor may include a channel for receiving and directing saliva to a suction drain and suction holes all in fluid communication with a dental office suction system. A suction extension may be affixed to the first and/or second bite platform to further evacuate saliva from entering the work field. The dental isolation block can be positioned such that the lip retractor retracts the upper lip if the work field is on the upper arch or to retract the lower lip if the work field in on the lower arch. | 2009-02-05 |
20090035719 | Disposable prophylaxis angle - A dental prophylaxis angle includes a body, a drive gear and a driven gear. The body has a sleeve with an open rear end, a neck, a head, a first axial bore, and a second axial bore. The first axial bore is located in the neck, and the second axial bore is located in the head. The first and second axial bores communicate with each other at an intersection. A channel extends through the body from the base of the neck to the open rear end. The drive gear is adapted to be inserted into said body through said head. The drive gear includes a gear, an intermediate portion and a shaft. The shaft extends rotatably from the open rear end of the sleeve, through the first bore, and into the second bore. The intermediate portion further includes an angled leading edge. The drive gear defines a circumferential groove between said gear and said intermediate portion. The driven gear is rotatably mounted in the head and operatively connected to the drive gear. The body further includes a lip extending into the channel. The lip is adapted to be received by the groove when the drive gear is inserted through said head. | 2009-02-05 |
20090035720 | Cure through laminate veneer applicator - An instrument to compressively place and bond a restorative covering to the surface of a tooth comprising a gripping body ( | 2009-02-05 |
20090035721 | DENTAL IMPLANT AND DENTAL IMPRESSION-TAKING DEVICE ASSEMBLY - The invention relates to an assembly formed by a dental implant ( | 2009-02-05 |
20090035722 | Hydroxyapatite coated nanostructured titanium surfaces - Nanotubular structured titanium (Ti) substrates have been coated with nanoparticulate hydroxyapatite (nano-HA). The nano-HA surface is highly adherent to the nanotubular Ti surface and is free of microparticles. The nano-HA coated nanotubular Ti surface promotes osteoblast cell adhesion and is particularly suitable for orthopedic and dental implants where deposition of osteoblasts and other proteins is important in bone formation. | 2009-02-05 |
20090035723 | MATERIAL WITH A REPETITIVE PATTERN OF MICRO-FEATURES FOR APPLICATION IN A LIVING ORGANISM AND METHOD OF FABRICATION - A material configured for implantation in a living organism. In some embodiments, the material includes a mechanical surface that has long range ordered micro-features. A repetitive pattern of hierarchical micro-features is incorporated in some embodiments, and in some embodiments the micro-features are composite in nature, and may include nano-structures. One embodiment provides a method of modifying the surface of a tissue in a living organism. The method includes a step of dividing a laser beam into a plurality of laser beams and a further step of guiding the plurality of laser beams to create an interference pattern at the surface of the material, and a repetitive pattern of micro-features is formed on the surface of the tissue. | 2009-02-05 |
20090035724 | Site Specific Intra-Oral Application Apparatus - An apparatus ( | 2009-02-05 |
20090035725 | PHOTODISINFECTION OF ORAL CAVITY - A composition for photodisinfection of the oral cavity comprising toothpaste and a photosensitizing composition encapsulated within microspheres, wherein the microspheres release the photosensitizing composition into the oral cavity upon contact with liquid and/or force and the photosensitizing composition includes a photosensitizer that upon irradiation of at least one predetermined wavelength will reduce and/or eliminate microbes in the oral cavity. The present invention also includes a method of applying the composition into the oral cavity and applying irradiation to the oral cavity at a wavelength or wavelengths absorbed by the photosensitizing composition so as to reduce or eliminate microbes in the oral cavity. | 2009-02-05 |
20090035726 | Dental Prosthesis - The method for producing ceramic coping of the present invention comprises the following steps: (i) covering a tooth model with at least one layer of plastic; (ii) coating a plastic covered tooth model from step (i) with alumina gel and letting it dry to form a ceramic coping in green state; (iii) sintering the ceramic coping in green state from step (ii) at a temperature up to 1200° C.; (iv) coating the ceramic coping from step (iii) with crystal hardening powder; (v) firing the crystal hardening powder coated ceramic coping from step (iv) at a temperature up to 1200° C. for effecting crystal hardening of the ceramic coping. Then, the finished ceramic coping can be coated with an outer aesthetic layer to form a dental prosthesis. | 2009-02-05 |
20090035727 | DENTAL DEVICE - A dental device including an elongated handle and an access handle formed along the elongated handle. A tip portion is formed at a distal end of the access handle and tapers to a point flocked with a plurality of bristles. A weakened portion is formed between the access handle and the elongated handle thereby permitting separation of the access handle and the tip portion relative to the elongated handle. | 2009-02-05 |
20090035728 | SELF-ETCHING EMULSION DENTAL COMPOSITIONS AND METHODS - The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface. | 2009-02-05 |
20090035729 | Apparatus for Chewing Obstruction - In one aspect, the present invention is directed to an apparatus for chewing obstruction, the apparatus comprising: a pad, the contour of which corresponds to the contour of one or more molar or premolar teeth; and an adherent, for adhering the pad to one or more molar teeth. Preferably, the thickness of the pad is substantially between 0.5 to 10 mm. The adherent may comprise an adhesive substance. The pad may comprise a flexible substance, such as a spongy material (e.g., polypropylene) and rubber. According to one embodiment of the invention, the adherent is adapted to lose the adhesiveness thereof after a certain time period. Preferably, the time period is between one and five hours. In another aspect, the present invention is directed to a medicament form, comprising: a pad in which a dissolving medicament is absorbed; and an adherent, for adhering said pad to one or more teeth. | 2009-02-05 |
20090035730 | Method and System for Fire Simulation - A fire simulation method and system for simulating ammunition from a weapon. The method includes determining a trajectory of the simulated ammunition, emitting a light beam along a simulation axis, and coding said light beam with information. The method includes determining a point in time when the simulated ammunition passes a target, determining a value related to the distance between the simulation axis and a momentary position of the simulated ammunition along the trajectory at that point in time, and emitting the light beam coded with the determined value during a predetermined time period. | 2009-02-05 |
20090035731 | Electromechanical Tactile Braille Cell Assembly - The present invention discloses an electromechanical tactile cell assembly comprising a plurality of piezoelectric element reeds, each one of the piezoelectric element reeds being bendable at an elongated end portion when a voltage is applied to the reed, a plurality of conductive fulcrum pins secured to a printed circuit board, and a plurality of multiple element conductive supports secured to a printed circuit board, each multiple element conductive support, in combination with the plurality of conductive fulcrum pins, adapted to secure a plurality of piezoelectric reeds, corresponding to the plurality of conductive fulcrum pins, to the printed circuit board. The electromechanical tactile cell is adaptable for use with a Braille display. | 2009-02-05 |
20090035732 | METHOD FOR LEARNING, TEACHING AND TRAINING DATACENTER IT SOLUTIONS, A DATACENTER IT SOLUTION KIT, AND A METHOD FOR TROUBLESHOOTING A DATACENTER - A set of pre-defined datacenter IT solution tasks which are to be performed by a user for setting up or for extending a datacenter is provided for a pre-defined IT solution. Groups of basic tasks and learning tasks are provided such that each learning task comprises one or more basic task. A sequence of interface tasks is assigned to the basic tasks and learning tasks. An interface task provides a predefined instruction or set of instructions for validation or for verification of the correctness of the performed learning task or interface task. This is done by evaluating a characteristic behaviour of the datacenter and not necessarily by monitoring each step of the user who is fulfilling the tasks. | 2009-02-05 |
20090035733 | DEVICE, SYSTEM, AND METHOD OF ADAPTIVE TEACHING AND LEARNING - Device, system, and method of adaptive teaching and learning. For example, a teaching/learning system includes a real-time class management module to selectively allocate first and second digital learning objects for performance, substantially in parallel, on first and second student stations, respectively. | 2009-02-05 |
20090035734 | Incrementally-sized dishware system and method of using same for weight management - An incrementally-sized dishware system and method for weight management gradually modifies food portion consumption behavior to provide healthier eating habits. The incrementally-sized dishware system and method includes a plurality of incrementally-sized plates having successively differentiated plate surface areas. Each of the incrementally-sized plate surface areas is successively different by an increment to modify food portion delivery to a user. When utilizing the incrementally-sized dishware system and method a user selects a starting plate surface area based on a combination of weight management factors, and over time successively shifts to plates having smaller/larger plate surface areas. Interval changes between the dishes of the incrementally-sized dishware system and method adjust the amount of food consumed and rate of weight loss over time. Children using the incrementally-sized dishware system and method learn to recognize an appropriate meal size for their body size and weight, and establish healthy eating habits that carry into adulthood. | 2009-02-05 |
20090035735 | SYSTEM AND METHOD FOR COMPUTERIZED TRAINING OF ENGLISH WITH A PREDEFINED SET OF SYLLABLES - Systems and methods for computerized teaching of the English language are disclosed. The disclosed embodiments comprise presenting a predefined set of syllables representing the English language to a student visually and audibly such that the user learns to read and write each syllable. Furthermore, the student may be instructed to read and write words of the English language not included in the examples shown in front of each syllable utilizing their knowledge of the syllables. | 2009-02-05 |
20090035736 | Real-time training simulation system and method - A training simulation method and system for training operational service units such as call centre or customer service centres personnel are provided, including providing a simulated scenario to personnel, the scenario progressing in scenario time and the scenario including a plurality of simulated events provided in a predetermined sequence in real time at predetermined scenario times within the scenario, and receiving responses to the events from personnel. The system can simulate scenarios, which unfold to personnel in real time, and the responses of the personnel can be received in real time, so adding to the realism of the simulation being provided. The personnel responses can be marked and assessed to give a competency rating for their responses. | 2009-02-05 |
20090035737 | Injection Training Pad - Disclosed is an injection training pad that allows a user to practice intradermal, subcutaneous and intramuscular injections all on the same device. The injection training pad includes a container having an open top and a closed bottom. A lid having a hole removably engages the open top of the container. The pad also includes a retaining member having a base with at least one leg. At least a portion of the retaining member is disposed within the container. A cap having a flange is positioned between the retaining member and the lid, and a cushion is positioned between the retaining member and the cap. | 2009-02-05 |
20090035738 | Tooth for tooth model, comprising enamel portion impregnated with resin or low melting point glass, and method for producing the same - An object of the present invention is to provide a tooth model capable of exhibiting grinding feel similar to that of a natural tooth, with which students aspiring to become dentists experience intraoral work and perform training related to a treatment, and also experience formation of an abutment tooth, formation of cavity or the like. A difference in the grinding feel between tooth enamel and dentin, which constitute a natural tooth, is reproduced by impregnating a sintered body formed integrally of an inorganic powder such as alumina with a thermosetting resin or a low melting point glass to form an enamel portion. | 2009-02-05 |
20090035739 | DENTAL SIMULATOR - Dental simulation apparatus comprising a six degrees of freedom motion actuator having an upper mobile portion; an artificial mandible secured to the mobile portion of the motion actuator, the artificial mandible being arranged to receive a plurality of artificial teeth or other dental restoratives; and an artificial maxilla rigidly located about the artificial mandible, the artificial maxilla also being arranged to receive a plurality of artificial teeth or other dental restoratives. | 2009-02-05 |
20090035740 | SYSTEMS AND METHODS FOR REMOTE CONTROLLED INTERACTIVE TRAINING AND CERTIFICATION - The present invention relates to systems and methods for training, testing and/or certifying one or more subjects (e.g., at the same time (e.g., in the use of an automated external defibrillator (AED) and/or cardiopulmonary resuscitation (CPR))). In particular, the present invention relates to remote bi-directional communications (e.g., data delivery, acquisition, and/or maintenance). For example, the present invention provides communication between a handheld AED simulation device (e.g., comprising a processor) and one or more simulation devices (e.g., a mannequin (e.g., comprising a processor and/or one or more sensors) connected thereto and/or components (e.g., controls and/or sensors) associated therewith. The present invention also provides a system configured to relay information (e.g., instructions and/or performance data) between one or more processors (e.g., housed on a personal computer or other device) and one or more additional processors (e.g., housed on a simulation device (e.g., a mannequin comprising one or more sensors (e.g., hall effect sensors and/or switch sensors associated therewith). | 2009-02-05 |
20090035741 | RIGID BIRTH SIMULATOR HAVING AN INTERACTIVE OPTICAL DISPLAY - The invention relates to a birth simulator having an interactive optical display for displaying prenatal handling methods and for simulating selected situations during birth. The birth simulator has the following features: A womb torso ( | 2009-02-05 |
20090035742 | ATOM MODELING KIT - A construction kit such as for the depiction of atoms and their electron arrangements in elements and compounds. This kit comprises a plurality of ring components each having plural connection points for connection to other ring components. The connection points typically comprise male connectors or female connectors with each ring component including one or more male connectors, one or more female connectors, or both male and female connectors, so that multiple ring components can be connected in different configurations to form three-dimensional objects in the form of hemispheres or spheres. | 2009-02-05 |
20090035743 | Assay System - The present invention provides an agglutination based assay system for determining the presence and/or amount of analyte in a sample comprising a test device having one or more capillary pathways comprising detection regions adapted for non-visual detection of a sample which is releasably engageable with a reader which comprises detection means for detecting the sample at the detection regions in each of said capillary pathways and electronic means for indicating the presence and/or amount of analyte. Also provided are the individual test device and reader components, and an assay method using the system. | 2009-02-05 |
20090035744 | Apparatus and Method for Separating and Storing Human Reproductive Material in a Cryotank - Apparatus and method for separating individual human reproductive material from a fertilization dish and storing the material in a cryotank for future fertilization and implantation. The apparatus includes an elongate cryostraw having a first open end and second heat-sealable open end, a channel extending between said ends, and an internal, calibrated volume VC. A displacement bulb is connected to the first end of the cryostraw for admitting and emitting the material into said cryostraw. The bulb has a total volume VB | 2009-02-05 |
20090035745 | Site-Specific Dosing of Cellular Cultures - Systems and methods for site-specific dosing of cellular cultures are provided. Some of the systems provided comprise at least two laminar flow channels; and an ablatable membrane that is disposed between the at least two laminar flow channels. Other systems provided comprise at least two laminar flow channels; and an ablated membrane that is disposed between the at least two laminar flow channels. Some of the methods provided comprise providing at least two laminar flow channels; providing a membrane disposed between the at least two laminar flow channels, wherein the membrane is selected from the group consisting of an ablatable membrane and an ablated membrane; placing cells into at least one of the at least two laminar flow channels; providing a reagent medium; and flowing the reagent medium through at least one other of the at least two laminar flow channels. | 2009-02-05 |
20090035746 | Device and Method for Preparing a Sample for an Analysis and Device and Method for Analyzing a Sample - A device and method are disclosed for preparing a sample for an analysis and a device and method are disclosed for analyzing a sample. In at least one embodiment, a device is disclosed for preparing a sample for analysis including means for binding at lest one biological structure of the sample, means for releasing at least one biological molecule contained in the at least one structure, and means for binding the at least one released molecule. The means for binding the at least one structure and the means for binding the at least one molecule can move. | 2009-02-05 |
20090035747 | Nucleic Acid and Gene Derived from Novel HCV Strain and Replicon-Replicating Cell Using Said Gene - The present invention relates to a gene derived from a novel fulminant hepatitis C virus strain, an HCV replicon RNA with a high replication efficiency obtained using the gene, and an HCV replicon-replicating cell transfected with the replicon RNA. When the HCV replicon RNA and the HCV replicon-replicating cell of the present invention are used, HCV proteins can be continuously produced in a large amount. | 2009-02-05 |
20090035748 | BROMELAIN AS A CLINICAL SAMPLE PRE-TREATMENT, LYSIS AGENT AND NUCLEASE INHIBITOR - This invention generally relates to the use of the proteolytic enzyme bromelain for treating samples for diagnostic assays. More specifically, the present invention relates to the use of bromelain in methods for pre-treating clinical samples primarily for the purpose of obtaining extractable and amplifiable DNA or RNA from prokaryotic or eukaryotic cells and/or viruses. The present methods also relate to using bromelain as a nuclease inhibitor. The use of bromelain as a nuclease inhibitor is useful in applications where the destructive nature of nucleases are detrimental to downstream applications. This invention also relates to the use of bromelain as a lysis agent for samples to be used, for example, in a molecular based diagnostic assay. The present methods include treating a sample which contains bacteria, viruses, host cells, fungi or parasites with bromelain, typically extracting nucleic acid from the sample, and subjecting the sample to a nucleic acid-based diagnostic assay. | 2009-02-05 |
20090035749 | ANALYSIS OF HIV-1 CORECEPTOR USE IN THE CLINICAL CARE OF HIV-1 INFECTED PATIENTS - A change in viral tropism occurs in many HIV positive individuals over time and can be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been shown to correlate with increased disease progression. In patients undergoing HAART, the predominant populations of virus can be shifted back to CCR5-mediated entry after the CXCR4-specific strains have emerged. The present invention relates to a diagnostic method to monitor coreceptor use in the treatment of human immunodeficiency virus (HIV) infection. The present invention further relates to a diagnostic method applied to HIV-positive individuals undergoing HAART to monitor the suppression of CXCR4 specific strains. The diagnostic methods can be used to assist in selecting antiretroviral therapy and to improve predictions of disease prognosis over time. | 2009-02-05 |
20090035750 | METHOD OF DETECTING HUMAN PAPILLOMA VIRUS BY USING NUCLEIC ACID AMPLIFICATION METHOD AND NUCLEIC ACID CHAIN-IMMOBILIZED CARRIER - Provided is a nucleic acid primer for LAMP amplification for use in the detection of human papilloma virus and identification of its genotype. The present invention also provides a method of detecting human papilloma virus and identifying its genotype, includes a step of amplifying the nucleic acid chains in a sample in LAMP reaction by using multiple primers including at least one primer selected from the nucleic acid primers according to the present invention and a step of detecting presence of amplified products after the amplification reaction and identifying their genotypes. | 2009-02-05 |
20090035751 | Single Molecule Detection Using Molecular Motors - The present invention provides methods and compositions for highly sensitive nucleic acid detection, down to the single nucleic acid molecule level. In one aspect, the present invention provides methods for detecting a target nucleic acid comprising: (a) providing first and second target-specific nucleic acids, wherein the first and second target-specific nucleic acids each comprise sequences complementary to the target nucleic acid; wherein the first target specific nucleic acid is bound to a first affinity tag and the second target-specific nucleic acid is bound to a second affinity tag, wherein the first affinity tag is capable of binding to a molecular motor, and wherein the second affinity tag is capable of binding to a detection probe; (b) contacting the first and second target-specific nucleic acids to a sample under conditions whereby the first and second target-specific nucleic acids will hybridize to the target nucleic acid if the target nucleic acid is present in the sample, wherein upon hybridization to the target nucleic acid the first and second target-specific nucleic acids are directly adjacent to each other; (c) ligating the first and second target-specific nucleic acids together; (d) binding the molecular motor t˜ the first affinity tag and the detection probe to the second affinity tag; (e) inducing movement of the molecular motor; and (f) detecting movement of the molecular motor through the detection probe, wherein the movement of the molecular motor serves to detect the target nucleic acid in the sample. | 2009-02-05 |
20090035752 | Polynucleotide Participating In Rheumatoid Arthritis And Utilization Of The Same - Analysis is made on the DNA methylation of the region (including a promoter region) upstream from the translation initiation point of a rheumatoid arthritis-associated gene DR3 in human genome. As a result, it is found out that an allele-specific methylation occurs in a CpG sequence located about −380 to −180 bp upstream from translation initiation point (ATG) of the gene DR3. It is further found out that the CpG sequences downstream therefrom of the genes DR3 originating in healthy subjects are all in the unmethylated state, while methylated and unmethylated sequences are both observed in the genes DR3 originating in RA patients. | 2009-02-05 |
20090035753 | Novel druggable regions in the dengue virus envelope glycoprotein and methods of using the same - The present invention relates to novel druggable regions discovered in dengue virus envelope glycoprotein, or dengue virus E protein, which is a class II viral E protein. The present invention further relates to methods of using the druggable regions to screen potential candidate therapeutics for diseases caused by viruses having class II E proteins, e.g. viral fusion inhibitors. | 2009-02-05 |
20090035754 | Methods and compositions for detecting steroids - The present invention provides for methods and systems for detecting steroids. Examples of such steroids include estrogen, progesterone, androgen, testosterone, and derivatives and analogs thereof. Systems useful for carrying out the method include tripartite constructs including a DNA-binding domain, a ligand binding domain, and an activation domain. The present invention provides numerous improvements over previous diagnostic systems for detection of steroids, such advantages include that the method allows for detection of steroid analogs and derivatives, whose structures may not yet be known, the method is generally applicable to a wide variety of organisms, and numerous ligand binding domains may be used in conjunction with the present system. | 2009-02-05 |
20090035755 | Yeast Strain And Screening Method For Identifying Inhibitors Of The Expression Of The Hexose Transporter Genes By A Positive Phenotype - The present invention provides screening procedures for identifying inhibitors of components of regulatory networks by a positive phenotype and modified yeast cell lines suitable for said screening. The screening procedures are especially suited to screen for substances that re-sensitize resistant pathogenic microorganisms or tumor cells by suspending the expression of resistance-relevant genes. The invention further provides methods for constructing said cell lines and their use in screening systems. | 2009-02-05 |
20090035756 | Methods for arbitrary peptide synthesis - Methods, apparatus, systems, computer programs and computing devices related to biologically assembling and/or synthesizing peptides and/or proteins are disclosed. | 2009-02-05 |
20090035757 | SUBSTRACTIVE SINGLE LABEL COMPARATIVE HYBRIDIZATION - Provided are methods of determining differences between nucleic acids in a test sample and a reference sample. In certain embodiments the methods are used for detecting and mapping chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases, or to detecting the phenomena of large scale copy number variants. In particular, provided are advanced methods of performing array-based comparative hybridization that allow reproducibility between samples and enhanced sensitivity by using the same detectable label for both test sample and reference sample nucleic acids. Invention methods are useful for the detection or diagnosis of particular disease conditions such as cancer, and detecting predisposition to cancer based on detection of chromosomal or genetic abnormalities and gene expression level. Invention methods are also useful for the detection or diagnosis of hereditary genetic disorders or predisposition thereto, especially in prenatal samples. Moreover, invention methods are also useful for the detection or diagnosis of de novo genetic aberrations associated with post-natal developmental abnormalities. | 2009-02-05 |
20090035758 | Method of Measurement of Micronucleated Erythrocyte Populations - A method of measuring micronucleated erythrocyte populations is disclosed. The method includes contacting a sample containing erythrocyte populations with a fluorescently labeled antibody specific to immature erythrocytes among erythrocyte populations; adding an aqueous permeation reagent to the sample and incubating the formed permeation sample mixture for an incubation time sufficient to allow the permeation reagent to render cellular membrane of the erythrocyte populations permeable to RNase and dye; adding a RNase reagent to degrade RNA and to inhibit further reaction of permeation reagent; adding a fluorescent nucleic acid dye reagent to stain DNA representing micronuclei in the erythrocyte populations; performing light scatter and fluorescence measurements of the final sample mixture on a flow cytometer; differentiating micronucleated erythrocyte populations from other cell types; and reporting the micronucleated erythrocyte populations of the sample. The method avoids ultracold fixation, centrifugation, and washing cells in sample preparation. | 2009-02-05 |
20090035759 | METHOD AND DEVICE FOR DETECTING THE PRESENCE OF A SINGLE TARGET NUCLEIC ACID IN A SAMPLE - A method comprises loading a sample portion into a sample chamber which comprises means for minimizing diffusion of the sample portion, subjecting the sample portion to an amplification step, and determining whether the sample portion contains at least one molecule of a target nucleic acid. If the sample portion contains a single molecule of the target nucleic acid, the sample portion would attain a detectable concentration of the target nucleic acid after a single round of amplification. Also, a microfluidic device comprising a sample portion and a sample chamber comprising means for minimizing diffusion of the sample portion. Also, a microfluidic device comprising a sample chamber and an amplification targeting reagent positioned in the first sample chamber. | 2009-02-05 |
20090035760 | CalDAG-GEF1 Gene Mutations Associated with Thrombopathy - The present invention relates to methods and compositions for detecting mutations associated with thrombopathy. In particular, the invention relates to methods and composition for detecting mutations in the CalDAG-GEF1 gene that are associated with thrombopathy. | 2009-02-05 |
20090035761 | Method for isolation of DNA, RNA and proteins from formalin-fixed paraffin-embedded tissue specimens - Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue. | 2009-02-05 |
20090035762 | Allele-specific copy number measurement using single nucleotide polymorphism and DNA arrays - Methods and systems for allelic detection and allele-specific copy number are provided herein. The described methods use identification of single nucleotide polymorphism using restriction enzymes and CGH analyses. Microarrays comprising probes designed by the described methods are provided. Also included are methods for identifying SNP sites and copy number in samples obtained from patient populations. | 2009-02-05 |
20090035763 | Methods for Detecting Progression of Low Grade Cervical Dysplasia and for Detecting Adenocarcinomas - The invention provides methods for identifying conditions of low grade cervical dysplasia and assessing the progressive potential of individual lesions to develop into high grade cervical dysplasia and cervical squamous cell cancer as well as cervical adenocarcinoma. | 2009-02-05 |
20090035764 | Methods and systems for evaluating CGH candidate probe nucleic acid sequences - Methods of evaluating candidate CGH probe nucleic acid sequences are provided. Aspects of the methods include providing a candidate CGH probe nucleic acid sequence for a target sequence of a copy number variation (CNV) of a genome. A proximity score is then determined for the candidate CGH probe nucleic acid sequence and employed to evaluate the sequence. Aspects of the invention further include computer programming and systems that include the same which are configured to evaluate candidate CGH probe nucleic acid sequences using a proximity score. | 2009-02-05 |
20090035765 | Polynucleotides and methods for making plants resistant to fungal pathogens - This invention relates to polynucleotide sequences encoding a gene that can confer resistance to the plant pathogen | 2009-02-05 |