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05th week of 2012 patent applcation highlights part 55
Patent application numberTitlePublished
201200290412-ARYL IMIDAZOLINE DERIVATIVES - 2-Aryl imidazoline derivatives are provided that are useful as anti-obesity agents or the like. A compound represented by Formula (I) or a pharmaceutically acceptable salt thereof: wherein R2012-02-02
20120029042CLONIDINE FOR TREATMENT OF BONE CANCER - The present invention is directed to a method for treating osteolytic bone cancer. The method comprises implanting a drug depot locally at or near the osteolytic bone cancer, wherein the drug depot comprises at least one biodegradable polymer and clonidine in an amount from about 0.1 wt. % to about 30 wt. % of the drug depot.2012-02-02
20120029043Pharmaceutical Composition Containing An N-Phenylpyrazole Derivative, And Use Thereof For Preparing A Topical Veterinary For Flea Control - The invention relates to a liquid pharmaceutical composition that contains an N-phenylpyrazole derivative as an active principle, benzyl alcohol, and an appropriately selected organic solvent, and to the use of such a composition for preparing a topically applied antiparasitic veterinary drug for preventing and/or treating flea infestation in pets, in particular in dogs and cats.2012-02-02
201200290447-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF - Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided.2012-02-02
20120029045METHOD FOR TREATING PORT WINE STAINS - A method of using photodynamic therapy to perform selective targeted therapy of biological tissue. The method includes intravenously injecting a porphyrin-based photosensitizing drug followed by irradiating the tissue with light while the drug is being injected. The duration of the irradiation and other parameters are controlled so that the selected biological tissue is treated and non-selected tissue is not damaged. By controlling the flow rate of the injection and other parameters, so that irradiation of the effected tissue overlaps with injection of drug, the target tissue is effectively treated without damage to non-target tissue.2012-02-02
20120029046CRYSTALLINE FORM OF SUNITINIB AND PROCESSES FOR ITS PREPARATION - The present invention relates to a novel crystalline form of sunitinib free base designated form I and to processes for its preparation. The invention also relates to its use as an API and in the preparation of various forms of sunitinib. Further, the invention relates to pharmaceutical compositions comprising the novel crystalline form and salts, solvates and hydrates prepared according to the invention, and to the uses of said pharmaceutical compositions in the treatment and/or prevention of cancer.2012-02-02
20120029047USE OF HDAC INHIBITORS FOR THE TREATMENT OF BONE DESTRUCTION - The present invention relates to the use of HDAC inhibitors for the treatment of bone destruction caused by cancer, inflammatory diseases and osteoporosis.2012-02-02
20120029048PHENYLALKYL N-HYDROXYUREAS FOR TREATING LEUKOTRIENE RELATED PATHOLOGIES - The method of treating patients by administering N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea for treatment of leukotriene related pathologies and compositions for this use.2012-02-02
20120029049Antisense Modulation of Superoxide Dismutase 1, Soluble Expression - Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding superoxide dismutase 1, soluble. Methods of using these compounds for modulation of superoxide dismutase 1, soluble expression and for treatment of diseases associated with expression of superoxide dismutase 1, soluble are provided.2012-02-02
20120029050COMPOSITIONS AND THEIR USES DIRECTED TO DIACYLGLYCEROL ACYLTRANSFERASE 1 - Disclosed herein are compounds, compositions and methods for modulating DGAT-1 activity. Preferably, the expression of DGAT-1 from a nucleic acid is inhibited. Methods are provided for treating, ameliorating or treating liver fibrosis, either directly or by treating an underlying etiological factor. Preferably, the treatment, amelioration or prevention comprises administering a DGAT-1 activity modulator.2012-02-02
20120029051siRNA Targeting VEGFA and Methods for Treatment In Vivo - Vascular endothelial growth factor A (VEGFA) is a chemical signal produced by cells that stimulates the growth of new blood vessels, and overexpression of VEGFA can lead to undesirable physiological conditions. Through the identification of new siRNA and modifications that improve the silencing ability of these siRNA in vivo, therapeutic compositions and methods have been invented to address the problems associated with this overexpression.2012-02-02
20120029052Short Interfering Ribonucleic Acid (siRNA) for Oral Administration - Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification.2012-02-02
20120029053Short Interfering Ribonucleic Acid (siRNA) for Oral Administration - Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification.2012-02-02
20120029054RNA Interference Mediated Inhibition of GATA Binding Protein 3 (GATA3) Gene Expression Using Short Intefering Nucleic Acid (siNA) - The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of GATA3 gene expression and/or activity, and/or modulate a GATA3 gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsR-NA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against GATA3 gene expression.2012-02-02
20120029055MODULATORS OF APOPTOSIS AND THE USES THEREOF - Here we demonstrate that miR-125b, a brain-enriched microRNA, is a negative regulator of p53 in animals. miR-125b-mediated downregulation of p53 is dependent on the binding of miR-125b to a microRNA response element in the 39 untranslated region of p53 mRNA. Overexpression of miR-125b represses the endogenous level of p53 protein and suppresses apoptosis in cells. In contrast, knockdown of miR-125b elevates the level of p53 protein and induces apoptosis in cells. This phenotype can be rescued significantly by either an ablation of endogenous p53 function or ectopic expression of miR-125b in zebrafish. Ectopic expression of miR-125b suppresses the increase of p53 and stress-induced apoptosis. Together, our study demonstrates that miR-125b is an important negative regulator of p53 and p53-induced apoptosis during development and during the stress response.2012-02-02
20120029056DIFFERENTIALLY EXPRESSED MICRORNAS AS BIOMARKERS FOR THE DIAGNOSIS AND TREATMENT OF SJOGREN'S SYNDROME - The identification of differentially expressed microRNAs in patients with Sjögren's syndrome is disclosed herein. Provided is a method of diagnosing a subject as having Sjögren's syndrome by measuring the level of at least one differentially expressed miR gene product identified herein. An alteration in the level of the at least one miR gene product in the biological sample of the subject relative to a control indicates the subject has Sjögren's syndrome. Also provided is a method of treating a patient with Sjögren's syndrome by administering to the patient a therapeutically effective amount of an agent that inhibits expression of a miR gene product that is up-regulated in the patient with Sjögren's syndrome relative to a control, or by administering to the patient a therapeutically effective amount of an isolated miR gene product that is down-regulated in the patient with Sjögren's syndrome relative to a control. A method of restoring salivary flow in a patient with Sjögren's syndrome is also provided.2012-02-02
20120029057Antisense Oligonucleotides for Inducing Exon Skipping and Methods of Use Thereof - An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.2012-02-02
20120029058Antisense Oligonucleotides for Inducing Exon Skipping and Methods of Use Thereof - An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.2012-02-02
20120029059Antisense Oligonucleotides for Inducing Exon Skipping and Methods of Use Thereof - An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.2012-02-02
20120029060Antisense Oligonucleotides for Inducing Exon Skipping and Methods of Use Thereof - An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.2012-02-02
20120029061RNA SEQUENCE-SPECIFIC MEDIATORS OF RNA INTERFERENCE - The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications.2012-02-02
20120029062Interior functionalized hyperbranched dendron-conjugated nanoparticles and uses thereof - Provided herein are nanoparticle platforms and combinatorial drug delivery vehicles comprising gold nanoparticles with a plurality of thilolated hyperbranched dendrons conjugated to the nanoparticle surface. The thiolated hyperbranched dendrons comprise chemically-modifiable surface groups, functionalized interior groups and nano-cavities within the hyperbranched structure to which a variety of payload molecules may be conjugated, optionally via a linker. Payload molecules may comprise nucleic acids, anticancer drugs and small molecule inhibitors, optionally with, non-cytotoxic signaling agents, for example, fluoroscein isothiocyanate. Also provided are methods for delivering one or more therapeutic agents to a cell or tissue or for treating a pathophysiological condition in a subject by delivering the combinatorial drug delivery vehicles to a cell or tissue associated with the pathophysiological condition to facilitate internalization of the vehicle to effect treatment.2012-02-02
20120029063CHIMERIC NK RECEPTOR AND METHODS FOR TREATING CANCER - The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.2012-02-02
20120029064 FORMULATION OF SILIBININ WITH HIGH EFFICACY AND PROLONGED ACTION AND THE PREPARATION METHOD THEREOF - A high-efficacy, long-acting formulation of silibinin, comprising silibinin solid dispersion, silibinin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the mass ratio of these components is silibinin solid dispersion:silibinin-loaded silica nanoparticles:slow-release matrix material:release enhancer=1:0.5˜1.25:0.1˜0.3:0.1˜0.3; the drug loading rate of the said silibinin-loaded silica nanoparticles is 51.29˜51.77%; the said silibinin solid dispersion contains povidone K30, soybean lecithin, acrylic resin IV, wherein the mass ratio between silibinin and other medical accessories is silibinin:povidone K30:soybean lecithin:acrylic resin IV=1:1˜3:0.3˜0.8:0.2˜0.5. Compared with the existing formulations, the half life of the high-efficacy, long-acting formulation of silibinin disclosed in this invention is 14.8 times longer while the mean residence time (MRT) of which is 4.52 times longer; when tested in vivo in Beagle dogs, this new formulation of silibinin presents a smoother concentration-time curve and reaches the continuous release for 72 hours. This invention discloses its preparation method.2012-02-02
20120029065COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS - Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.2012-02-02
20120029066USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS - Novel Use of flavones having 2-phenylchromen-4-one skeleton is disclosed herein. The flavones are useful as lead compounds for manufacturing a medicament or a pharmaceutical composition for treating a patient diagnosed with a psychiatric disorder with sensorimotor gating deficits.2012-02-02
20120029067Polyphenol Proteasome Inhibitors, Synthesis, and Methods of Use - The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.2012-02-02
20120029068TRANSDERMAL FLUID - The present invention relates to a transdermal fluid. The transdermal fluid containing an active amount of a tocotrienol is described, useful for the treatment or prevention of a cancer or a tumour or an inflammatory disorder, particularly breast cancer. The fluid can be used either in combination with known medication or exclusively.2012-02-02
20120029069Compound Extracted From Antrodia Cinnamomea and Pharmaceutical composition comprising the same - This invention relates to a novel compound extracted from 2012-02-02
20120029070BURDOCK FRUIT EXTRACT CONTAINING ARCTIGENIN AT HIGH CONTENT AND PROCESS FOR PRODUCING SAME - PROBLEM TO BE SOLVED2012-02-02
20120029071COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING RADIATION INJURY - The invention provides compositions and methods featuring Nrf2 activators for treating or preventing radiation-associated tissue damage.2012-02-02
20120029072PLEUROMUTILIN DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY MICROBES - Disclosed are pleuromutilin derivatives of formula (I)2012-02-02
20120029073PHARMACEUTICAL COMPOSITIONS HAVING DESIRABLE BIOAVAILABILITY - The present invention is directed to the provision of pharmaceutical compositions. The compositions include a therapeutic agent and a relatively low amount of surfactant for providing higher bioavailability of the therapeutic agent. The compositions are particularly desirable as ophthalmic compositions in which the therapeutic agent is a prostaglandin such as travoprost and the surfactant is a vegetable oil such as castor oil.2012-02-02
20120029074CONTROLLING TRANSGENE EXPRESSION ACROSS THE SKIN - The invention relates to the use of a skin permeating compound such as phloretin for controlling transgene expression under control of the 2012-02-02
20120029075COMPOSITIONS CONTAINING C1 TO C7 ORGANIC ACID MONOGLYCERIDES AND GLYCEROL, THEIR PREPARATION AND USE AS ANTIBACTERIALS AND ANTI-MOULD AGENTS - Described are antibacterial and anti-mould compositions containing high amounts of C2012-02-02
20120029076MICRONIZED POLYMER POWDER AND COSMETIC COMPOSITION THEREOF - The invention provides a micronized polymer powder compos Won for the use in personal care and cosmetics, the micronized polymer powder composition comprising at least one thermoplastic polyester based on at least one diol and at least one dicarboxylic acid selected from the group consisting of cyclic and branched aliphatic dicarboxylic acids having 4-12 carbon atoms and aromatic dicarboxylic acids having 8-12 carbon atoms. The present invention provides also a cosmetic composition comprising the at least one micronized polymer powder composition according to the invention.2012-02-02
20120029077Animal Feed Additive and Animal Feed Comprising Alkyl Esters of Medium Chain Fatty Acids, and their Use in Animal Feed - The invention is directed to an animal feed suitable for feeding mammals, birds and fish, comprising an alkyl ester of a fatty acid, wherein said fatty acid has a chain length of 5-12 carbon atoms, and wherein the dosage of said ester in said animal feed is 50 ppm by weight or higher, based on the total weight of said animal feed.2012-02-02
20120029078COMPOSITIONS COMPRISING MYRISTIC ACID AND USES THEREOF - The teachings herein are directed to antibacterial and anti-inflammatory pharmaceutical compositions that include myristic acid. Further embodiments herein are directed to methods of administering sufficient amounts of myristic compositions to patients in need thereof in order to prevent or treat inflammation and/or bacterial infection. Myristic acid has been established to outperform other cetylated fatty acids in treating infection and inflammation, such as 1-TDC which includes cetylated myristic acid. The compositions and methods provided herein can further be used with additional anti-inflammatory, antibacterial, and delivery agents.2012-02-02
20120029079PHARMACEUTICAL COMPOSITIONS CONTAINING FLUORINATED OR PERFLUORINATED CARBOXYLIC ACIDS - The molecules of formula (I) are useful in treating diabetes, obesity, hypercholesterolaemia, hyperlipidaemia, cancer, inflammation or other conditions in which modulation of lipis of eicosanoid status or functions may be desirable. Formula (I): Z2012-02-02
20120029080REDUCTION OF RISK OF OBESITY - A nutritional composition comprising a significant amount of arachidonic acid (ARA) is described. Such nutritional composition is particularly suitable for infants below the age of 3 years, preferably between birth and 12 months of life. The composition can be used to reduce the risk of developing overweight/obesity and/or insulin resistance later in life.2012-02-02
20120029081Solid Pharmaceutical Compositions Containing Pregabalin - A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone.2012-02-02
20120029082NUTRITIONAL OR THERAPEUTIC COMPOSITIONS TO INCREASE BODILY GLUTATHIONE LEVELS - Nutritional or therapeutic compositions containing glutamic acid, cystine, glycine and a selenium precursor and methods for their utilization to increase glutathione synthesis and thereby enhance the immune system are described.2012-02-02
20120029083POLYMORPHIC FORMS OF ALISKIREN HEMIFUMARATE AND PROCESS FOR PREPARATION THEREOF - Provided are amorphous and polymorphic forms of aliskiren hemifumarate, pharmaceutical compositions thereof, and processes for their preparation.2012-02-02
20120029084Topical Nepafenac Formulations - Topical suspension compositions of nepafenac are disclosed. The compositions are especially suitable for topical ophthalmic administration.2012-02-02
20120029085STABILIZATION OF QUINOL COMPOSITION SUCH AS CATECHOLAMINE DRUGS - Compositions and methods are provided for obtaining stabilized quinol compositions, such as catecholamine drugs (e.g., epinephrine solutions), and also for obtaining stable pharmaceutical formulations that comprise a stabilized quinol composition and a second pharmacologically active component such as a local anesthetic or other active drug ingredient having a reversibly protonated amine group. Stability is achieved through the inclusion of an appropriately selected pH buffer and a thiol agent, based on redox and pH buffering principles including pKa of the buffer and of the reversibly protonated amine group.2012-02-02
20120029086Compositions and Method for Temporary Reduction of Nasal and Sinus Pain - Compositions and method that are expedient, safe, non-habit forming, and non-sedating for temporary reduction of nasal and sinus pain comprised of a local anesthetic or local anesthetics in a pharmaceutically acceptable carrier by instillation into the nasal cavity and sinuses by method of nasal spray. 2012-02-02
20120029087USE OF RASAGILINE FOR THE TREATMENT OF OLFACTORY DYSFUNCTION - Disclosed are methods of treating olfactory dysfunction by periodically administering a therapeutically effective amount of rasagiline or a pharmaceutically acceptable salt of rasagiline to a subject.2012-02-02
20120029088ANTI-ANXIETY COMPOSITION - This invention provides a highly safe anti-anxiety composition that can be used for treatment or prevention of anxiety disorders. Such anti-anxiety composition comprises, as an active ingredient, a carotenoid.2012-02-02
20120029089PREPARING BIODEGRADABLE HYDROGEL FOR BIOMEDICAL APPLICATION - Biodegradable dextran based hydrogel suitable for biomedical application is produced by subjecting polysaccharide substituted with unsaturated moiety, e.g. dextran methacrylate, in aqueous medium to UV or visible light irradiation in the precense of riboflavin/L-arginine or riboflavin/chitosan to cause photocrosslinking of polysaccharide substituted with unsaturated moiety.2012-02-02
20120029090Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them - Modified alkoxylation products of the formula (I), their use and processes for preparing them2012-02-02
20120029091METHOD OF CONTROLLING THE RELEASE OF AN ACTIVE INGREDIENT FROM A DOSAGE FORM - A method of controlling or adjusting release of an active ingredient from a dosage form comprising the active ingredient and a polysaccharide derivative has been found. The method comprises the steps of 2012-02-02
20120029092PRODUCT CONTAINING DIAMIDES, METHOD FOR MAKING SAME AND USES THEREOF - The product comprises at least two diamide compounds selected from the diamide compounds of following formulae (Ia), (Ib), and (Ic):2012-02-02
20120029093SYSTEM AND METHOD FOR RECYCLING SURFACTANT IN EMULSION PRODUCTION - A system for producing emulsions includes a liquid supply system, an emulsification system in liquid connection with the liquid supply system to receive a first liquid and a second liquid from the liquid supply system while in operation to be used to produce an emulsion therefrom, and a surfactant recovery system connected to the emulsification system to receive the emulsion when produced from the first and second liquids. The second liquid is immiscible with the first liquid, and the surfactant recovery system recovers at least a portion of surfactant from the emulsion when the emulsion is received from the emulsification system. A method of producing an emulsion includes providing first and second immiscible liquids, emulsifying the first and second liquids to provide an emulsion comprising a plurality of droplets of the first liquid in the second liquid, the emulsion having a first concentration of a surfactant, subjecting the emulsion to a change in an environmental condition that causes the surfactant to coalesce into localized regions of concentrated surfactant, and removing at least some of the localized regions of concentrated surfactant from the emulsion such that the emulsion has a second concentration of the surfactant that is less than the first concentration of the surfactant.2012-02-02
20120029094CELLULAR FOAM ADDITIVE - Highly specialized three-dimensional structural kinetic mixing particles to promote low surface energy regions for bubble and nucleation sites resulting in stronger, lighter weight foam having consistent cellular structures. The foam composition includes particles that continue to remain active as foam constituent fluids move during the foam expansion process. The continued mixing promotes better dispersion of blowing agents as well as increased mobility through better dispersion of reactive and nonreactive additives throughout the polymer during expansion of the foam thereby improving cellular consistency. The addition of kinetic mixing particles will produce similar results in any structural foam material that uses endothermic blowing agents, exothermic blowing agents and/or gas foam injection systems.2012-02-02
20120029095Sabatier process and apparatus for controlling exothermic reaction - A Sabatier process involving contacting carbon dioxide and hydrogen in a first reaction zone with a first catalyst bed at a temperature greater than a first designated temperature; feeding the effluent from the first reaction zone into a second reaction zone, and contacting the effluent with a second catalyst bed at a temperature equal to or less than a second designated temperature, so as to produce a product stream comprising water and methane. The first and second catalyst beds each individually comprise an ultra-short-channel-length metal substrate. An apparatus for controlling temperature in an exothermic reaction, such as the Sabatier reaction, is disclosed.2012-02-02
20120029096OLEFIN SELECTIVE FT CATALYST COMPOSITION AND PREPARATION THEREOF - The present invention relates to a hydrocarbon synthesis catalyst comprising in its unreduced form a) Fe as catalytically active metal, b) an alkali metal and/or alkaline-earth metal in an alkali metal- and/or alkaline-earth metal-containing promoter, the alkali metal, c) and a further promoter comprising, or consisting of, one or more element(s) selected from the group of boron, germanium, nitrogen, phosphorus, arsenic, antimony, sulphur, selenium and tellurium, to a process for the synthesis of a hydrocarbon synthesis catalyst, to a hydrocarbon synthesis process which is operated in the present of such a catalyst and to the use of such a catalyst in a hydrocarbon synthesis process.2012-02-02
20120029097SHAPE MEMORY MATERIALS COMPRISING POLYELECTROLYTE SEGMENTS - The present invention concerns shape memory materials comprising polyelectrolyte segments. These segments can be used for fixing a permanent shape and/or such segments can also be employed as switching segments responsible for the fixation and release of the temporary shape.2012-02-02
20120029098PROTON CONDUCTING MATERIALS - Materials are provided that may be useful as ionomers or polymer ionomers, including compounds including bis sulfonyl imide groups which may be highly fluorinated and may be polymers.2012-02-02
20120029099POLYMER ELECTROLYTE MATERIALS BASED ON BLOCK COPOLYMERS - The present invention relates generally to electrolyte materials. According to an embodiment, the present invention provides for a solid polymer electrolyte material that has high ionic conductivity and is mechanically robust. An exemplary material can be characterized by a copolymer that includes at least one structural block, such as a vinyl polymer, and at least one ionically conductive block with a siloxane backbone. In various embodiments, the electrolyte can be a diblock copolymer or a triblock copolymer. Many uses are contemplated for the solid polymer electrolyte materials. For example, the novel electrolyte material can be used in Li-based batteries to enable higher energy density, better thermal and environmental stability, lower rates of self-discharge, enhanced safety, lower manufacturing costs, and novel form factors.2012-02-02
20120029100PROCESS FOR PRODUCING CATION EXCHANGERS - Strongly acidic cation exchangers with high mechanical, osmotic and oxidation stability can be prepared by sulfonating bead polymers formed from one or more vinylaromatic monomer(s), one or more crosslinker(s) and from 0.2 to 20% by weight of one or more vinyl ethers and/or vinyl esters.2012-02-02
20120029101EXPANDED POLYPROPYLENE COPOLYMER RESIN PARTICLES - Disclosed is an expanded polypropylene copolymer resin particle whose base resin is a polypropylene random copolymer resin having a melting point of not more than 145° C., the base resin having a H/W ratio of not more than 8 where H (%) is a maximum height of an elution peak and W (° C.) is a peak width at half a height of the peak in an elution curve obtained from a differential value of eluted content measured by cross fractionation chromatography, and a ratio (Mw/Mn) of a weight-average molecular weight (Mw) and a number-average molecular weight (Mn) being not less than 3.5 in a molecular weight distribution measurement of a whole of eluted components. With such an expanded polypropylene copolymer resin particle, it is possible to provide expanded polypropylene copolymer resin particles which are capable of producing an in-mold expansion-molded article with a low molding heating vapor pressure, and which causes few deformation or shrinkage of an obtained in-mold expansion-molded article (i.e. having a broad molding heating temperature range) even if the in-mold expansion molding is carried out with a high molding heating vapor pressure and has a low decrease in physical properties such as compression strength.2012-02-02
20120029102FRACTURE FIXATION SYSTEMS - Systems for bone fracture repair are disclosed. One system includes a biocompatible putty that may be packed about a bone fracture to provide full loadbearing capabilities within days. The disclosed putties create an osteoconductive scaffold for bone regeneration and degrade over time to harmless 2012-02-02
20120029103POLYMER FOAM AND FOAM ARTICLES FOR FIRE PROTECTION - The invention provides a cellular polyurethane foam composition for forming a cellular ceramic under fire conditions, the composition comprising: at least 40% by weight based on the total weight of the composition of a polyurethane; from 10% to 40% by weight based on the total weight of the composition of silicate mineral filler; from 5% to 20% by weight based on the total weight of the composition of at least one inorganic phosphate that forms a liquid phase at a temperature of no more than 800° C.; from 0.1% to 10% by weight based on the total weight of the composition of a heat expandable solid material; and wherein the total proportion of inorganic components constitutes in the range of from 20% to 60% by weight of the total composition.2012-02-02
20120029104COMPOSITION COMPRISING STABLE POLYOL MIXTURES - Single-phase fluid compositions, comprising at least two isocyanate-reactive polyol components which are inherently incompatible with each other and as a mediator additive at least one copolymer compatibilizer additive effectuating compatibility between the originally incompatible polyol components, said copolymer comprising structural units having at least one nitrogen group which can be protonized.2012-02-02
20120029105METHOD FOR CREATING A FOAMED MASS SYSTEM - A method for producing a foamed mass system comprising thermally sensitive substances, wherein the mass system is foamed at a first temperature in a first step, and the thermally sensitive substances are added to the mass system in a subsequent step at a second temperature lower than the first temperature2012-02-02
20120029106METHOD FOR PRODUCING LOW-CHLORINE POLYBIPHENYL SULFONE POLYMERS - The present invention relates to a process for the production of low-chlorine-content polybiphenyl sulfone polymers, to the polybiphenyl sulfone polymers obtainable in this way, to polybiphenyl sulfone polymers with less than 800 ppm content of organically bonded chlorine, to thermoplastic molding compositions and moldings, fibers, films, membranes, or foams comprising the polybiphenyl sulfone polymers mentioned, and also to their use for the production of moldings, of fibers, of films, of membranes, or of foams.2012-02-02
20120029107NOVEL OLIGOFUNCTIONAL PHOTOINITIATORS - The invention pertains to novel oligofunctional photoinitiators of the formula (1) or (1A). R2012-02-02
20120029108UV-CURABLE INK JET INK COMPOSITION - A UV-curable ink jet ink composition contains a polymerizable compound, a photopolymerization initiator containing an acylphosphine-based photopolymerization initiator having a phenyl group in the molecule thereof, and a fluorescent brightening agent. The fluorescent brightening agent in a predetermined concentration has a higher maximum absorbance than the photopolymerization initiator in the same concentration, in a wavelength region of 360 to 420 nm.2012-02-02
20120029109PRODUCING COMPOSITE NANOPARTICLES CONTAINING ORGANIC IONS - A method for producing a composite nanoparticle, including the steps of, collapsing at least a portion of a polyelectrolyte polymer in solution about one or more precursor moieties to form a composite precursor moiety having a mean diameter in the range between about 1 nm and about 100 nm, wherein the polyelectrolyte polymer has an extended conformation in a first solution state and a more compact conformation in a second solution state; and cross-linking the polyelectrolyte polymer of the composite precursor moiety to form a composite nanoparticle wherein the precursory moiety is a charged organic ion.2012-02-02
20120029110PHOTOPOLYMERIZABLE RESIN COMPOSITION FOR TRANSFERRING MICROSTRUCTURE - A photopolymerizable resin composition for transferring a microstructure, which allows a thinner and uniform thin film to be formed, a transfer accuracy of extremely smaller microfine pattern to be excellent, and a curing time of the thin film to be shortened, is provided. The photopolymerizable resin composition for transferring a microstructure comprises the following component (A), component (B), component (C), component (D) and component (E) at the rate described below: 2012-02-02
20120029111AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF - The present invention provides an amphiphilic polysiloxane prepolymer which comprises hydrophilic monomeric units derived from at least one hydrophilic vinylic monomer, polysiloxane crosslinking units derived from at least one polysiloxane crosslinker having at least two terminal ethylenically-unsaturated groups, dangling polysiloxane chains each of which is terminated with one ethylenically unsaturated group, and chain-transfer units derived from a chain transfer agent other than a RAFT agent. A prepolymer of the invention is suitable for making hydrogel contact lenses. The present invention is also related to hydrogel contact lenses made from an amphiphilic polysiloxane prepolymer of the invention and to processes for preparing an amphiphilic polysiloxane prepolymer of the invention and for making silicone hydrogel contact lenses.2012-02-02
20120029112Biopolymer Compositions Having Improved Impact Resistance - The present disclosure is directed to polymer blends comprising a biopolymer and one or more impact modifiers, wherein at least one impact modifier is an ester of formula I:2012-02-02
20120029113PHENOLIC RESIN COMPOSITION FOR SHELL MOLDING, RESIN COATED SAND FOR SHELL MOLDING, AND SHELL MOLD FORMED OF THE SAME - Provided are a phenolic resin composition for shell molding that has low thermal expansion properties and high flexibility, a resin coated sand for shell molding obtained by using the same, and a shell mold formed of the same. The phenolic resin composition for shell molding that is capable of exhibiting advantageous mold characteristic is obtained by a combination of a phenolic resin that is obtained by a reaction of a phenol, a naphthol, and an aldehyde, and a fatty acid amide.2012-02-02
20120029114TIRE WITH RUBBER COMPONENT - Pneumatic rubber tire with a component comprised of a silica reinforced rubber composition comprised of specialized polybutadiene rubber, functionalized styrene/butadiene elastomer and cis 1,4-polyisoprene rubber.2012-02-02
20120029115ROOM-TEMPERATURE CURABLE EPOXY STRUCTURAL ADHESIVE COMPOSITION AND PREPARATION METHOD THEREOF - A room-temperature curable epoxy structural adhesive composition comprises Component A and Component B, wherein Component A comprises a bisphenol A type epoxy resin, an impact resistance modified bisphenol A type epoxy resin, a silane coupling agent, a thixotropic agent and a coloring agent, wherein Component B comprises a polyamide, a polyether amine, a filler and a curing accelerator, wherein said impact resistance modified bisphenol A type epoxy resin is a liquid NBR modified bisphenol A type epoxy resin and/or a core-shell structural polymer toughened bisphenol A type resin. In addition, a preparation method of the said adhesive composition is provided.2012-02-02
20120029116CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS - The invention provides an improvement to the useable lifetimes of phenolic-epoxy, phenolic-benzoxazine, phenolic-epoxy-benzoxazine mixtures and other phenolic mixtures through the use of protected phenolics, where a phenolic compound, polymer, or resin is released on demand by the addition of a deblocking agent.2012-02-02
20120029117ADHESIVE FILM FOR SEMICONDUCTOR ASSEMBLY - An adhesive film composition includes a polymer binder; a curable resin; and about 40 to about 60 wt. % of solvent, wherein the solvent is a binary solvent consisting essentially of at least a first solvent with a boiling point of about 40° C. to about 100° C. and at least a second solvent with a boiling point of about 140° C. to about 200° C.2012-02-02
20120029118TOUGHENED RESIN FIBER LAMINATES WITH TITANIUM PARTICLES - A composite structure includes at least one resin matrix layer having a resin material and a plurality of fiber elements and a plurality of titanium particles provided in the resin material. A method of toughening a resin matrix layer is also disclosed.2012-02-02
20120029119REDISPERSIBLE POLYMER POWDERS PREPARED FROM BLENDS OF CARBOXYLATE - A water redispersible polymer powder is produced by drying an aqueous mixture of a high T2012-02-02
20120029120SYSTEMS AND METHODS FOR REMOVING FINELY DISPERSED PARTICULATE MATTER FROM A FLUID STREAM - Disclosed are methods of removing particulate matter from potash tailings fluid. The invention includes providing an activating material capable of being affixed to the particulate matter, affixing the activating material to the particulate matter to form an activated particle, providing an anchor particle and providing a tethering material capable of being affixed to the anchor particle; and attaching the tethering material to the anchor particle and the activated particle to form a removable complex in the potash tailings fluid. The invention also includes providing an activating material capable of being affixed to the particulate matter in the potash tailings fluid; affixing the activating material to the particulate matter to form an activated particle; providing an anchor particle and enveloping it with an enveloping agent to form an enveloped anchor particle capable of attaching to the activated particle; and combining the enveloped anchor particle with the activated particle to form a removable complex.2012-02-02
20120029121THIN ALUMINIUM FLAKES - The present invention relates to aluminium flakes having a thickness between 7 and 9 nm, coating compositions containing them and the use of the coating compositions for forming (security) products. When the compositions of the present invention are used in coating a hologram the obtained products show an extremely bright OVD image and extremely strong rainbow effect, high purity and contrast.2012-02-02
20120029122FLAME RETARDANT MOLDING COMPOSITIONS - Thermoplastic molding compositions, comprising 2012-02-02
20120029123Fibrous Basic Magnesium Sulfate-Containing Pellets and Production of Molded Propylene Polymer Products - Fibrous basic magnesium sulfate-containing pellets comprising an olefin polymer and fibrous basic magnesium sulfate in a weight ratio of 80:20 to 20:80 and further comprising a nucleating agent in an amount of 0.3 to 8 weight parts based on 100 weight parts of the olefin polymer and in an amount of 0.2 to 4 weight parts based on 100 weight parts of the fibrous basic magnesium sulfate are favorably employable for producing molded fibrous basic magnesium sulfate-containing propylene polymer products which show high flexural modulus, high flexural strength and high yield strength in tension as well as excellent thermal stability.2012-02-02
20120029124Halogen Free Flame Retardant Polyamide Composition - A polymer composition comprising (i) at least one semi-aromatic polyamide having a melting point of at least 270° C., (ii) at least one organophosphorous compound selected from phosphinates, diphosphinates and condensation products thereof, and (iii) at least 0.01 wt. %, based on the total weight of the composition, of calcium oxide.2012-02-02
20120029125HYDROSTABLE POLYETHERIMIDE BLENDS, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM - A composition comprising, based on the total weight of the composition, from 10 to 90 wt. % of a polyetherimide with a weight average molecular weight from 10,000 to 80,000 Daltons; from 10 to 90 wt. % of a polymer selected from polycarbonates, polyester-polycarbonates, polyalkylene terephthalates, or a combination thereof, from 0.005 to 1 wt. % of a hydrotalcite having a particle size of less than 10 micrometer and a magnesium oxide to aluminum oxide mole ratio of 1.0 to 5.0; from 0.01 to 1.0 wt. % of a phosphorus-containing stabilizer; from 0.01 to 1.00 wt. % of a hindered phenol stabilizer; optionally, from 0 to 3 wt. % of a polyolefin; and optionally, from 0 to 5 wt. % of an inorganic metal oxide.2012-02-02
20120029126Method of Reducing Chatter - A method for reducing chatter in an extrusion process, which includes the steps of preparing an extrusion composition by combining a polymer composition with a chatter-reducing formulation, and extruding the extrusion composition to provide a substantially continuous extrudate. The chatter-reducing formulation comprises an alkyltin mercaptide and dibutyltin dilaurate. The resultant extrudate exhibits reduced chatter, which is categorized according to the Reed Scale as less than or equal to 2.2012-02-02
20120029127COATING STRUCTURE, CHEMICAL COMPOSITION FOR FORMING THE SAME, AND METHOD OF FORMING THE SAME - A coating structure includes a UV-cured resin layer and a fluoride monomolecular layer. Organosilicon groups of organosilicon molecules extend from the surface of the resin layer. Wax fine powder and oxide nanoparticles emerge from the surface of the resin layer to form mountain-valley-like microstructures. Fluoride molecules of the fluoride monomolecular layer are chemically bonded with the surface of the resin layer to expose the fluoride groups. During the formation of the coating structure, the UV-curable resin layer is first partially cured, then the fluoride molecules are activated to chemically bond to the surface of the resin layer, and thereafter, the UV-curable resin layer is completely cured.2012-02-02
20120029128Aqueous resin composition - There is provided a practically useful aqueous resin composition which enables to obtain a coating film that is satisfactory not only in corrosion resistance but also in coating adhesion when applied over a metal surface, specifically an aqueous resin composition which enables, in a form of a thin film having a thickness of about 0.1-5 μm, to exhibit various properties practically required for surface treating agents for chromium-free surface-treated steel plates, namely excellent corrosion resistance, adhesion to steel plates, durability against alkaline degreasing agents or solvents which are used for removing a press oil used during press molding, adhesion to an overcoating material which is used for aesthetic purposes, mechanical stability and the like. The aqueous resin composition comprises 100 parts by mass of a copolymer of an α,β-ethylenically unsaturated carboxylic acid and an olefin; and 0.1-10 parts by mass of a carboxylic acid polymer2012-02-02
20120029129POLYAMIDE/POLY(ARYLENE ETHER) COMPOSITION, ARTICLE, AND METHOD - A polyamide-poly(arylene ether) composition is prepared by melt blending specific amounts of components including a polyamide, a poly(arylene ether), a hydrogenated block copolymer of an alkenyl aromatic monomer and a conjugated diene, a compatibilizing agent, and partially saponified ester of a C2012-02-02
20120029130GOLF BALL MATERIAL AND METHOD OF PREPARING THE SAME - The invention provides a golf ball material which is a resin mixture composed of (a) a nonionic olefin-unsaturated carboxylic acid copolymer and/or olefin-unsaturated carboxylic acid-unsaturated carboxylic acid ester copolymer, (b) a nonionic olefin-unsaturated carboxylic acid copolymer and/or olefin-unsaturated carboxylic acid-unsaturated carboxylic acid ester copolymer, (c) an organic acid or a metal salt thereof, (d) a basic inorganic metal compound for neutralizing at least 70 mol % of acid groups in components (a) to (c), and (e) a spherical inorganic filler, which resin mixture has a Shore D hardness of from 40 to 60. The golf ball material of the invention provides an excellent rebound resilience and durability while maintaining the flow properties essential for injection molding.2012-02-02
20120029131Use Of Nonionic Surfactants As Emulsifiers For Emulsion Polymerization (III) - The invention relates to the use of aqueous solutions of nonionic surfactants as gel phase free emulator systems for the emulsion polymerization, wherein said nonionic surfactants are chosen from the group (a) of the addition products from 1 to 40 mol ethylene and/or propylene oxide per mol of allyl alcohol, and (b) of the addition products from 1 to 40 mol ethylene and/or propylene oxide per mol of allyl alcohol, wherein the OH-group of said addition products is end-capped in the sense that it is substituted by a group OR, wherein R is an alkyl group with 1 to 20 C-atoms, which can be saturated or unsaturated, straight chained or branched.2012-02-02
20120029132AQUEOUS DISPERSION, ITS PRODUCTION METHOD, AND ITS USE - Aqueous dispersions including at least one thermoplastic resin; at least one dispersing agent; and water; wherein the dispersion has a pH of less than 12 are disclosed along with dispersions including at least one thermoplastic resin; at least one dispersing agent; and water wherein the dispersion has a volume average particle size of less than about 5 μm. Some dispersions include less than about 4 percent by weight of the dispersing agent based on the weight of the thermoplastic resin. Other dispersions include at least one propylene-rich alpha-olefin interpolymer; at least one dispersing agent; and water. Methods of making such dispersions are also described.2012-02-02
20120029133POLYAMIDE MOULDING COMPOUND FOR PRODUCING MOULDED ARTICLES WITH A SOFT-TOUCH SURFACE AND ALSO CORRESPONDING MOULDED ARTICLES - The invention relates to a polyamide moulding compound for producing moulded articles with a soft-touch surface, the polyamide moulding compound comprising a blend of an amine-terminated, amorphous polyamide and styrene-ethylene/butylene-styrene copolymer and also styrene-ethylene/butylene-styrene copolymer grafted with maleic anhydride. The invention relates furthermore to moulded articles which are produced with this moulding compound and the use thereof.2012-02-02
20120029134POLYAMIDE COMPOSITIONS WITH IMPROVED SALT RESISTANCE AND HEAT STABILITY - Disclosed is a polyamide composition including at least one semi-aromatic copolyamide, said semi-aromatic copolyamide consisting essentially of about 25 to about 55 mole percent repeat units of the formula2012-02-02
20120029135Polyphenylene Sulfide Synthetic Hair Filaments And Processes For Preparing The Same - The present invention provides a polyphenylene sulfide synthetic hair filament. The synthetic hair filament comprises (A) a polyphenylene sulfide resin; and (B) an inorganic particle quencher additive, wherein said PPS resin melt index range is 60˜110, wherein said inorganic quencher additive is added at 0.1˜2.0 parts by weight on a 100 parts by weight PPS resin. The synthetic hair filament has a filament size of about 30 to about 80 dtex. The polyphenylene sulfide resin (A) has a p-phenylene sulfide repeating unit above 85% mole. The inorganic particle quencher additive may be of silicon dioxide, talc or the combinations thereof. A suitable inorganic particle quencher additive has an average diameter range of 0.01˜3.0 μm.2012-02-02
20120029136HYDROPHILIC SILICA AS FILLER FOR SILICONE RUBBER FORMULATIONS - Provided is a hydrophilic precipitated silica which is well suited to use in silicone rubber formulations (RTV-1, RTV-2, HTV and LSR), particularly well suited to use in HTV silicone rubber formulations. It has a BET surface area of 185˜260 m2012-02-02
20120029137LONG-FIBER REINFORCED POLYESTERS - The invention relates to thermoplastic molding compositions comprising: 2012-02-02
20120029138Anti-settling composition and methods for use - An anti-settling additive, compositions containing anti-settling additives and methods for use, the additive containing a monomer or polymer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C2012-02-02
20120029139BLOCK COPOLYMERS HAVING ASSOCIATIVE GROUPS, AND ADHESIVE CONTAINING SAME - The present invention relates to a hot-melt adhesive that comprises a block copolymer having associative groups containing a nitrogen heterocyclic compound. The invention also relates to block copolymers having associative groups specifically adapted for implementation in a hot-melt adhesive2012-02-02
20120029140LOW-STAINING ROOM TEMPERATURE CURABLE COATING COMPOSITION - The present invention provides a low-staining room temperature curable coating composition having an excellent low-staining property and recoatability, and comprising (A) a hydroxyl-containing resin, (B) an isocyanate based curing agent, (C) an organosilicate based hydrophilizing agent, (D) a recoatability modifier and (E) an organic solvent, in which the recoatability modifier (D) comprises at least (D1) an amide-containing polymer and (D2) a silane coupling agent.2012-02-02
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