05th week of 2012 patent applcation highlights part 52 |
Patent application number | Title | Published |
20120028740 | HEIGHT ADJUSTMENT MECHANISM FOR A BASKETBALL SYSTEM - In one example, a basketball system includes a basketball goal, a support structure, a connecting structure connecting the basketball goal and the support structure, and a height adjustment mechanism connected to the support structure and the connecting structure. The height adjustment mechanism includes: a biasing mechanism connected at least indirectly to the connecting structure and including a locking pin movable between a first position where the biasing mechanism is locked and a second position where the biasing mechanism is unlocked; and, a handle including an outer surface configured such that rotation of the handle results in a corresponding linear movement of the locking pin as the outer surface slidingly engages the locking pin. The height adjustment mechanism is configured such that a single movement of the handle is sufficient to effect both unlocking of the biasing mechanism and adjustment of a height of the basketball goal. | 2012-02-02 |
20120028741 | ARROW POINT ALIGNMENT SYSTEM - An arrow apparatus includes a hollow arrow shaft, an arrow point alignment structure, an arrow point, and a central connection member. The hollow arrow shaft has an outer surface, an interior, and a leading end surface. The arrow point alignment structure includes a tapered portion and is positioned on the outer surface of the arrow shaft at a location proximal of the leading end surface of the arrow shaft. The arrow point is in contact with the tapered portion of the arrow point alignment structure. The central connection member extends into the interior and in contact with the leading end surface. | 2012-02-02 |
20120028742 | SCENT SHOOTER - A scent shooter apparatus and scent filled pellet is disclosed. The scent shooter may include a projectile launcher. A vessel may be coupled to the projectile launcher and configured to hold a pellet and release the pellet during operation of the apparatus. The apparatus may include a piercer mounted on the vessel. The piercer may be disposed to pierce the pellet during operation of the apparatus. The scent filled pellet may include a hardened shell. A control release agent may be disposed inside the pellet to control release of the scent. | 2012-02-02 |
20120028743 | Toy Ball Apparatus with Reduced Part Count - A toy ball apparatus is disclosed herein that includes a mesh defining an outer surface of the toy ball apparatus. The mesh includes four mesh components that are coupled together to enclose a closed volume, each mesh component including a plurality of loop structures, each loop structure having a curved inner perimeter surface formed to at least partially surround a hole communicating with the closed volume and surrounded at least partially by a polygonal outer perimeter. Each mesh component has cooperative mating surfaces formed along an outer perimeter of the mesh component, the cooperative mating surfaces being formed along at least a portion of the outer perimeter of each of a plurality of the loop structures in the mesh component. The adjacent mesh components are joined together along the cooperative mating surfaces. | 2012-02-02 |
20120028744 | BELT TENSIONING UNIT - A belt tensioning unit ( | 2012-02-02 |
20120028745 | IDLER AND BEARING ASSEMBLY AND A METHOD OF MANUFACTURING SAME - The assembly comprises a bearing unit ( | 2012-02-02 |
20120028746 | TRANSMISSION FOR USE IN A MOTOR AND A PEDAL-POWERED VEHICLE AND TRANSMISSION METHOD THEREOF - A transmission for use in an electrically-driven bicycle and/or a scooter is disclosed, in which the transmission coupled with a motor is embedded together with the motor in a hub of a rear or front wheel. According to the transmission and a transmission method, the power generated from the motor or a pedal is outputted through a transmission device to a hub shell of the wheel. The output of the motor or other output of the motor which is subject to a reduction unit is used as the input of the transmission device. A one-way clutch to which the power of a driver is received in a one-way rotation manner is prepared to the other side of the input of the transmission device, while the input of the transmission device is commonly used as a carrier for a series of planetary gears in the transmission device. The carrier includes a multistage planetary gear coupled with the carrier by means of a pin; sun gears, engaged with their respective planetary gears of the multistage planetary gear and selectively confined to the shaft by an external speed change lever; a ring gear, engaged with the multistage planetary gear, for transferring a gear shifted power of the transmission device to the hub shell; a first speed pawl, coupled with the carrier by means of the pin, for directly transferring the power of the carrier to the ring gear by being coupled with gear teeth of the ring gear when every sun gear is not confined to the shaft by the external speed change lever; a transmission control unit, manipulated by the external speed change lever, for selectively confining the sun gears to the shaft. The ring gear and the hub shell are connected to each other with an output pawl, so that the power cannot be reversely inputted when the hub shell is rotated with a higher speed than the ring gear. | 2012-02-02 |
20120028747 | VEHICULAR POWER TRANSMISSION DEVICE - Power generated by an engine is inputted to a carrier of a first planetary gear mechanism. Power generated by a motor is inputted to a sun gear of a second planetary gear mechanism. Power from a ring gear of the first planetary gear mechanism and power from a carrier of the second planetary gear mechanism are combined and transmitted to an axle of driving wheels. While power input from the engine to the carrier of the first planetary gear mechanism is maintained, rotation of a sun gear of the first planetary gear mechanism is restricted with a first clutch, a second clutch or a first brake. While power input from the motor to the sun gear of the second planetary gear mechanism is maintained, rotation of a ring gear of the second planetary gear mechanism is restricted with a second brake or a third clutch. | 2012-02-02 |
20120028748 | LUBRICATION SYSTEM FOR A PLANETARY GEAR SET - A planetary gear set for a transmission, the planetary gear set having a sun gear, a ring gear and a carrier assembly. The carrier assembly includes an annular first carrier member, at least one pinion pin, and at least one planet gear assembly. The first carrier member has at least one radial groove connecting a step surface to an inner surface of a pinion pin bore. A pinion pin has a bearing surface and a bore. The bore has a first and a second open end, the first open end in communication with the bearing surface the second open end in communication with the radial groove of the carrier member. | 2012-02-02 |
20120028749 | VEHICLE POWER TRANSMISSION DEVICE - A power transmission apparatus for a vehicle is provided which is equipped with a power split device and a speed variator. The power transmission device is designed to set a speed ratio of speed of rotation of an output of a power source to speed of rotation of a driven wheel in a power circulation mode of a power split device to lie within one of a positive range in which a sign of the speed ratio is positive and a negative range in which a sign of the speed ratio is negative. This results in a decrease in degree of torque acting on the speed variator such as a continuously variable transmission, thus permitting a required degree of durability of the speed variator to be reduced. | 2012-02-02 |
20120028750 | DIFFERENTIAL GEAR AND VEHICLE PROVIDED WITH DIFFERENTIAL GEAR - A differential gear is structured such that a first differential case and a second differential case overlap one another in the radial direction such that a first joining portion of the first differential case, i.e., a portion of an outward flange that is on the outer peripheral side of a through-hole, is positioned on the outer peripheral side of a second joining portion of the second differential case, i.e., a joining protrusion that is inserted in the through-hole. In addition, the ring gear is arranged facing those joining portions in the direction of the axis, and laser beam welded from the outer peripheral side at the portion where the ring gear faces both of those joining portions. Accordingly, the three members, i.e., the first differential case, the second differential case, and the ring gear, are all integrally joined together by a single welding operation, and manufacturing costs can be reduced. | 2012-02-02 |
20120028751 | Shift mechanism for a planetary gear transmission - A shift mechanism for a transmission comprising a planetary gear transmission, a shift cam engaged with a planetary gear assembly in the planetary gear transmission, the shift cam having a shift cam stop, a rotatable cable ring connected to a moveable cable, the cable ring comprising a ramped portion, a rotatable ramped ring, the ramped ring comprising a ramped portion cooperatively engaged with the cable ring ramped portion, and further the ramped ring having a stop cooperatively engagable with the shift cam stop, a rotation of the cable ring urges the ramped ring a predetermined distance in a direction normal to the plane of rotation of the cable ring, the shaft cam held against rotation by engagement with the ramped ring, and at which predetermined distance the ramped ring is allowed to rotate with the cable ring simultaneous with the axial movement of the ramped ring, and a spring connected between the cable ring and the shift cam, the shaft cam reacting to the spring force rotates upon rotation of the ramped ring by an amount of rotation that is limited by engagement of the shift cam stop with the ramped ring stop and during which rotation of the shift cam the transmission shifts gears. | 2012-02-02 |
20120028752 | FLYWHEEL MODULE - A flywheel module comprises a coupling unit which has an input shaft and an output shaft. This coupling unit has a first coupling of which a first coupling half can be connected to a combustion engine and a second coupling half can be connected to a continuously variable transmission. The flywheel module further comprises a flywheel unit which has an in/output and is formed by a flywheel and a reduction gear unit connected to the flywheel. This flywheel unit is exclusively connected to the in/output via the coupling unit. | 2012-02-02 |
20120028753 | Electric power tool - An electric power tool includes a cylindrical reducer case accommodating the speed reduction mechanism. The speed reduction mechanism includes a planetary gear train and a movable member which is axially slidable to be engaged with or disengaged from the planetary gear train. The electric power tool includes the reducer case including a slide hole formed through a sidewall of the reducer case and axially extended and a rotary plate which is rotatable around a periphery of the reducer case about the axis, the rotary plate including an operation slot formed axially obliquely and overlapped with the slide hole; a supporting member radially outwardly protruded from the movable member and extended through the slide hole and the operation slot; and a biasing unit for applying a pressing force to the supporting member in a moving direction of the supporting member when the rotary plate is rotated to a position. | 2012-02-02 |
20120028754 | LIQUID EQUALIZED GEAR SYSTEM AND METHOD FOR USING SAME - A carrier for use in a planetary gear system. The carrier has a plurality of openings or slots offset from a midline thereof. The carrier includes alignment mechanisms positioned in each of the plurality of openings or slots to substantially align each planet gear about the midline of the carrier. The carrier may be used in a planetary gear system for use in a wind turbine. One aspect incorporates eccentric rings in the openings. Another aspect incorporates inserts in the slots. Each of the rings and inserts has openings that, when properly positioned, will substantially bisect the carrier midline. | 2012-02-02 |
20120028755 | PIN FOR PLANETARY GEAR SYSTEM - A pin for coupling a planet gear to a carrier in a planetary gear system is disclosed. The pin includes a first end, a second end, and an outer surface extending between the first end and the second end. In some embodiments, the pin further includes means for modifying the compliance of the pin at an interface between the pin and the carrier. In other embodiments, the pin further include a compliance feature defined in the outer surface, the compliance feature allowing greater compliance of the pin in the tangential direction than in the radial direction. | 2012-02-02 |
20120028756 | COMPLIANT CARRIER WALL FOR IMPROVED GEARBOX LOAD SHARING - A planetary gear system and a method of fabricating same. The planetary gear system includes at least one planet gear, at least one planet pin receiving the at least one planet gear, and a carrier. The carrier itself includes at least one carrier opening for accommodating the at least planet gear, at least one planet pin opening for receiving the at least one planet pin, and at least one flex portion within a wall of the carrier for providing enhanced compliance to the carrier in response to force directed on the at least one planet gear. | 2012-02-02 |
20120028757 | CONTROL APPARATUS FOR HYBRID VEHICLE - In a hybrid vehicle having a locking mechanism in which a play elimination process is required in the locking, a torque shock in the play elimination is reduced. In a hybrid vehicle | 2012-02-02 |
20120028758 | DIRECT INJECTION ALCOHOL ENGINE WITH BOOST AND SPARK CONTROL - Boosted engine operation and spark timing of an engine may be adjusted with alcohol content of the fuel in a direct injection engine. Further, various adjustments may be performed in numerous related systems to account for increased maximum engine torque, such as traction control, transmission shifting, etc. | 2012-02-02 |
20120028759 | VEHICULAR POWER TRANSMISSION CONTROL APPARATUS - When a gear position at a higher speed range than a “specific gear position at a lower speed range” (e.g., first speed) is determined (when the torsional vibration is difficult to occur), a clutch torque is controlled such that a clutch is in a totally engagement state (a revolution speed Ne of an output shaft of an engine=revolution speed Ni of an input shaft of a transmission). On the other hand, when the “specific gear position at the lower speed range” (e.g., first speed) is determined (when the torsional vibration is easy to occur), the clutch torque is controlled such that the clutch is in the semi-engagement state (Ne−Ni=predetermined positive value A). In the semi-engagement state, a “damping action by a slip on the clutch” is acted on the torsional vibration, whereby the amplitude of the torsional vibration can be reduced. | 2012-02-02 |
20120028760 | PORTABLE ISOMETRIC EXERCISE DEVICE AND METHOD - The present invention is a portable isometric exercise device with resistance generated by a spring force including an electronic light or sound indicator to signal that a constant force level is being maintained. When a force is applied to the spring and a desired level of resistance is achieved, a continuous signal will be generated to advise the user that the isometric force exercise is being maintained. If the force is reduced, the signal will terminate to advise the user that the user has not maintained the required level of resistance. | 2012-02-02 |
20120028761 | INTERFACING PORTABLE MEDIA DEVICES AND SPORTS EQUIPMENT - Circuits, methods, and apparatus that allow sports or other equipment, such as gym or other cardio equipment, to write data to a media player. Examples further provide the uploading of this data to a computer and third-party website. To monitor progress, the third-party website can be used to track workout data over time. The third party-website can also collect data from other users, which is particularly useful for providing a competitive environment. This data can then be graphically displayed in various ways to provide encouragement. | 2012-02-02 |
20120028762 | Methods and Computer Program Products For Providing Audio Performance Feedback to a User During an Athletic Activity - Methods and computer program products for providing audio performance feedback to a user during an athletic activity are disclosed. In an embodiment, a method for providing audio performance feedback to a user during an athletic activity using a portable fitness monitoring device includes the steps of the portable fitness monitoring device receiving one or more audio feedback files, the portable fitness monitoring device generating audio performance feedback during the athletic activity by reference to an index, wherein the index is associated with the one or more audio feedback files, and the portable fitness monitoring device providing the audio performance feedback to the user during the athletic activity audibly through an audio output device. | 2012-02-02 |
20120028763 | TRAMPOLINE WITH SLEEVE JOINT COUPLING - A trampoline is disclosed that includes first, second, and third frame members, a pole member, and a sleeve joint coupling. The sleeve joint coupling includes a first arm with a first passage, a second arm with a second passage, a third arm extending away from the second arm and including a third passage, and an aperture. The first passage has a first axis, and the second and third passages shares a substantially common axis. The first axis is substantially perpendicular to the substantially common axis. The first frame member is received in the first passage, the second frame member is received in the second passage, the third frame member is received in the third passage, and the pole member is received in the aperture to extend away from the first frame member. At least one of the second and third arms defines an uppermost surface of the sleeve joint coupling. | 2012-02-02 |
20120028764 | HAND-EXERCISING AND WRIST-MASSAGING PLATFORM - A platform ( | 2012-02-02 |
20120028765 | ADJUSTABLE STANDING MUSCULAR RELEASING AND STRETCHING EXERCISE DEVICE - The present invention is an adjustable standing muscular releasing and stretching exercise device for a user. The device has a vertical linear column base, a support handle that can be vertically moved and attached along the linear base, a pair of adjustable releasing rollers on a horizontal bar with a roller connection that is movably connected to the linear base, a horizontal floor base that is attached to and supports the linear base, a raised non-skid foot platform that is attached to and extends over said floor base and an adjustable non-skid calf step perpendicularly and slidably attached to said foot platform. | 2012-02-02 |
20120028766 | Weight Lifting Sandals - A weight lifting system consisting of thin light-weight sandals to be strapped to a person's shod feet, the sandals having additional parts that are designed to attach to and detach from corresponding hardware on weights and weight holding devices. The sandals are designed and built so they will not interfere with walking or other exercises. The hardware works quickly and easily and a plurality of different weights is preferred with the net result being that the user can quickly and easily pick up and put down weights with their feet, change the amount of weight, and change weights from foot to foot and, hence, can easily move from one exercise to another, and there is no need to remove the sandals when performing other exercises. | 2012-02-02 |
20120028767 | Weights for Weight Lifting Shoes and Sandals - Weights and weight holding devices with hardware that is designed to attach to corresponding parts on shoes or sandals. The hardware works quickly and easily with the net result being that the user can quickly and easily pick up and put down weights with their feet, change the amount of weight, and change weights from foot to foot enabling the user to easily move from one exercise to another, and there is no need to remove the shoes or sandals when performing other exercises or walking. | 2012-02-02 |
20120028768 | Adjustable Weighted Exercise Method and Apparatus - Disclosed is an adjustable weighted exercise apparatus which in one implementation may include a base frame assembly attachable to a strap assembly for connection to a user, the base frame assembly including a base frame; a weight support member connected to the base frame and disposed to maintain a weight at a distance from the user. In some implementations, the weight support member may be further connected to at least one support bar connected to the base frame. A method hereof may include enhancing exercise of a body including disposing a weight at a distance from a user's body; and, exercising the user's body. | 2012-02-02 |
20120028769 | AIR-BRAKE SAFETY DEVICE FOR EXERCISE RESISTANCE BAND - A parachute-like safety device for use with an exercise resistance band. The parachute-like device can attach to the ends of the band to act as handles, and furthermore, such a device can be used at the center portion of a typical exercise resistance band. The benefit of either use, is that in the event of the accidental release (snap back) of any part of the device, the parachute-like device will “catch-air” and function as an air-brake as it is forced to rapidly move through the air, so as to slow down movement of the resistance band and therefore diminish or prevent injury caused by the snap-back effect. | 2012-02-02 |
20120028770 | PORTABLE EXERCISE DEVICE AND METHOD - A portable exercise device comprising: a support member, configurable to be installed such that it is generally stationary when in use; a first rotatable hand grip device attached to the support member, the rotatable hand grip device comprising: a first housing attached to the support member; a first grip rotatable within the first housing, the rotation taking place generally within an imaginary plane that is generally perpendicular to the direction of earth's gravity, and where the first grip is generally sized so that a user's hand can grasp and hold on to the first grip; a second rotatable hand grip device attached to the support member, the rotatable hand grip device comprising: a second housing attached to the support member; a second grip rotatable within the second housing, the rotation taking place generally within an imaginary plane that is generally perpendicular to the direction of earth's gravity, and where the second grip is generally sized so that a user's hand can grasp and hold on to the second grip. A method of using a portable exercise device with rotating grips, the method comprising: grasping grips in a chin-up position; pulling body up towards the grips; rotating grips into a pull-up position; finishing pulling body to the top of the exercise position, but with hands in a pull-up position; beginning to lower body back to a starting position; rotating the grips of both hands back to a chin-up position; and completing a repetition of the exercise back at the start position, with hands in a chin-up position. A method of using a portable exercise device with rotating grips, the method comprising: grasping grips in a pull-up position; pulling body up towards the grips; rotating grips into a chin-up position; finishing pulling body to the top of the exercise position, but with hands in a chin-up position; beginning to lower body back to a starting position; rotating the grips of both hands back to a pull-up position; and completing a repetition of the exercise back at the start position, with hands in a pull-up position. | 2012-02-02 |
20120028771 | AUTOMATIC TOOL STORING MECHANISM - An automatic tool storing mechanism which has a plurality of magazine, transporting means, and a tool exchanging part. Each magazine holds a number of pots each provided with tools. The transporting means transports tool-mounted pots one by one between the position close to the magazine and the waiting position close to the main spindle. The tool exchanging arm takes out an unused tool from the pot which is waiting at the waiting position and attaches it to the main spindle and also removes the used tool from the main spindle and places it in the pot. (FIG. | 2012-02-02 |
20120028772 | ROLLER COMPRISING A DRIVE SHAFT AND A ROLLER RING, AS WELL AS A METHOD FOR ASSEMBLING SUCH A ROLLER - The invention relates to a roller of the type that comprises, on one hand, a drive shaft, which has a cylindrical envelope surface having a certain outer diameter and a certain length, and, on the other hand, a shorter roller ring, which includes an outer ring of a hard material and an inner ring concentric with the same and of a more ductile material, which includes a cylindrical inside having a certain inner diameter and is, on one hand, permanently united to the outer ring in a metallurgical way, and, on the other hand, rotationally rigidly connected with the drive shaft in order to, from the same, transfer torque to the outer ring. According to the invention, the rotationally rigid joint between the drive shaft and the roller ring solely consists of a shrink-fit joint that is established between the envelope surface of the drive shaft and the inside of the inner ring and has an interference of at least 0.01% of the outer diameter of the drive shaft. | 2012-02-02 |
20120028773 | Method For Repairing A Roller, And Roller - The invention relates to a method for repairing a printing roller having a roller base body made ( | 2012-02-02 |
20120028774 | APPARATUS AND METHOD FOR LOADING CAVITIES OF PLUG SPACE PLUG FILTER ROD - An apparatus for serially delivering filling media to spaced apart cavities of an endless filter rod, which includes a conveyor which conveys a strip of plug wrap along a feed path, a transfer wheel arrangement which serially delivers filter segments to the plug wrap as it moves along the feed path such that the filter segments are arranged in plug-space-plug relation with cavities separated by the filter segments, and a filling wheel which rotates about a horizontal axis and includes pockets or cleats which receive filling media at the loading zone and deliver the filling media to the cavities at a discharge station along the feed path. | 2012-02-02 |
20120028775 | THERMAL CONTAINER - A thermal insulating liner for a container lid has a top sheet and a bottom sheet spaced by a core. The bottom sheet has an exterior metal foil layer. A side edge-to-side edge transverse cut line extends through the bottom sheet proximate each of two opposed ends of the liner. The liner has reduced thickness end margins extending between each said side edge-to-side edge transverse cut line and each of the opposed ends. A die to make the lid liner has a central well and, proximate each end of the die, an upward step to a land with an inside edge of the step having a ramp surface. A first cutting blade protrudes upwardly from the land and a second cutting blade protrudes upwardly above the land at each end of the die and above the level of the first cutting blade. | 2012-02-02 |
20120028776 | AUTOMATED GLUING DEVICE - A gluing device for automatically gluing and folding a gluable item. The gluing device includes a support structure upon which a gluing apparatus and a support plate assembly are mounted. The support plate is configured for supporting and aligning a gluable item for gluing and assembly by the gluing apparatus. The gluing apparatus includes a first clamp configured for selectively and securely holding a first portion of the gluable item on the support plate, a glue dispensing nozzle fluidly coupled to a glue supply, and a folding apparatus configured for folding the first portion of the gluable item onto a second portion of the gluable item after glue has been applied. A method for automatically gluing and folding a gluable item is also disclosed. | 2012-02-02 |
20120028777 | Method for producing an absorbent disposable incontinence diaper and apparatus for conducting the method - The invention relates to a method for producing an absorbent disposable incontinence diaper ( | 2012-02-02 |
20120028778 | Sheet Processing Apparatus and Image Forming Apparatus - A finisher deforms a fold end portion of a sheet bundle with a lower pressing plate and an upper pressing plate. A pressing unit holds a sheet bundle so that the fold end portion is positioned between the lower pressing plate and the upper pressing plate. A third pressing roller includes a third pressing surface that presses the fold end portion of the sheet bundle between the lower pressing plate and the upper pressing plate. The third pressing roller moves in between the lower pressing plate and the upper pressing plate. The third pressing roller or the pressing unit moves so that the third pressing surface of the third pressing roller presses the fold end portion at a predetermined position based on a tip of the fold end portion. The fold end portion projects after the sheet bundle is held between the lower pressing plate and the upper pressing plate. | 2012-02-02 |
20120028779 | SHEET PROCESSING APPARATUS, IMAGE FORMING SYSTEM AND SHEET PROCESSING METHOD - According to one embodiment, a sheet processing apparatus includes a reinforce roller to further reinforce the fold of a sheet which has been folded by a fold roller pair, a support portion to move the reinforce roller from a home position in a direction perpendicular to a sheet conveying direction, a motor to drive the support portion, a sensor to sense a position of the support portion, and a control unit which, in case that the sensor senses a position where the support portion abnormally stops, controls the support portion to move from the abnormally stopped position to a second position which is different from a first position that is a home position. | 2012-02-02 |
20120028780 | SHEET PROCESSING APPARATUS, IMAGE FORMING SYSTEM AND SHEET PROCESSING METHOD - According to one embodiment, a sheet processing apparatus includes a reinforce roller to further reinforce the fold of a sheet which has been folded by a fold roller pair, a support portion to move the reinforce roller in a direction perpendicular to a sheet conveying direction, a motor to drive the support portion, and a control unit to control the motor so that the support portion moves at a faster moving speed at the time of a homeward route than a moving speed at the time of an outward route. | 2012-02-02 |
20120028781 | SHEET FOLDING APPARATUS, IMAGE FORMING APPARATUS USING THE SAME, AND SHEET FOLDING METHOD - A sheet folding apparatus includes: a saddle-stitching unit configured to stitch a center of a sheet bundle; a folding unit configured to fold the sheet bundle at the center to form a fold; a loading base onto which the sheet bundle conveyed from the folding unit is loaded; a nipping plate configured to be pressed to and separated from the loading base in parallel to the loading base and to nip the sheet bundle loaded onto the loading base; and first and second rollers that move along a direction of the fold while nipping and pressing the fold of the sheet bundle nipped by the nipping plate to reinforce the fold. Here, a surface, which faces the loading base, of the nipping plate is provided with an elastic member. | 2012-02-02 |
20120028782 | POWER RINGS - In a decanter centrifuge a bowl is provided and rotates in use around a horizontal axis of rotation, a base plate provided at one longitudinal end of said bowl, the base plate having an internal side and an external side, an outlet opening provided in said base plate, the outlet opening extending through a first angular interval relative to the axis of rotation, and a wall projecting from the external side of said base plate, wherein the wall extends from the vicinity of the outlet opening towards a rim of the base plate, the wall extending through a second angular interval, the second angular interval being at least 30°, and the wall having in a radial plane perpendicular to the axis of rotation an inclination relative to the radial direction of at least 60°. | 2012-02-02 |
20120028783 | Plasticized vinyl acetate coplymer binder compositions for chopped strand mat - A plasticized binder composition suitable as a binder for chopped strand mats comprising (a) a copolymer obtainable by reacting; (i) 60-95 pphwm of vinyl acetate; and (ii) 5-40 pphwm of vinyl ester of α-substituted alkanoic acid; and b) a plasticizer, wherein the weight ratio of copolymer/plasticizer is from 1 to 6. | 2012-02-02 |
20120028784 | PROCESS FOR PRODUCING ALUMINUM TITANATE-BASED FIRED BODY - The invention is to provide a process which can produce a fired body comprising aluminum titanate-based ceramics being excellent in thermal decomposition resistance and having high mechanical strength. The invention is a process for producing an aluminum titanate-based fired body, comprising a step of firing a shaped body of a starting material mixture which contains an aluminum source powder and a titanium source powder, and the aluminum source powder satisfies the following formula (1). In the formula, D90 is a particle diameter corresponding to a cumulative percentage of 90% on a volume basis and D10 is a particle diameter corresponding to a cumulative percentage of 10% on a volume basis, and these are determined from a particle size distribution of the aluminum source powder measured by a laser diffractometry. | 2012-02-02 |
20120028785 | OPTICAL GLASS - The invention provides a novel optical glass which has a refractive index (nd) of 1.78 to 2.2 and an Abbe value (νd) of 16 to less than 40 and is suitable for precision mold press molding by virtue of its having a low glass transition temperature, namely, an optical glass which contains by mole in terms of oxides 25 to 60% B | 2012-02-02 |
20120028786 | FABRICATION OF CORDIERITE ARTICLE USING WASTE STEEL SLAGS - A method of fabricating a cordierite article from one or more steel slags such as blast furnace slag, converter slag and electric furnace slag. The cordierite article is useful for a particulate filter such as Diesel Particulate Filter. | 2012-02-02 |
20120028787 | DIELECTRIC CERAMIC COMPOSITION, DIELECTRIC BODY, CERAMIC SUBSTRATE, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING DIELECTRIC BODY - An electronic component | 2012-02-02 |
20120028788 | Age-Resistant Catalyst for Oxidation of NO to NO2 in Exhaust Streams - The present invention relates to a zeolite comprising platinum. The invention furthermore relates to a method for producing said zeolite comprising platinum according to the invention, to the use of said zeolite as an oxidation catalyst and hydrocarbon reservoir and to a catalyst component comprising the zeolite according to the invention. | 2012-02-02 |
20120028789 | CATALYST FOR REDUCING NITROGEN OXIDES AND METHOD FOR PRODUCING THE SAME - The object is to provide an exhaust gas reduction catalyst that exhibit high nitrogen oxide reduction performance, and to provide a simple and efficient method for producing the catalyst, in which the amount of the waste liquid is reduced, further, an object of the invention is to provide a zeolite-containing catalyst for reducing nitrogen oxides, which does not use an expensive noble metal or the like and which has high nitrogen oxide reduction performance. The present invention relates to a catalyst for reducing nitrogen oxides, which comprises: zeolite at least containing an aluminium atom and a phosphorus atom in the framework thereof; and a metal supported on the zeolite, wherein a coefficient of variation of intensity of the metal is at least 20%, when performing an elemental mapping of the metal in the catalyst with an electron probe microanalyzer, and, a catalyst for reducing nitrogen oxides, which comprises the zeolite containing at least a silicon atom, a phosphorus atom and an aluminium atom, and having an adsorption retention rate of at least 80% in a water vapor cyclic adsorption/desorption test at 90° C. | 2012-02-02 |
20120028790 | NON-PLATINUM OXYGEN REDUCTION CATALYSTS FOR POLYMER ELECTROLYTE MEMBRANE FUEL CELL AND METHOD FOR PREPARING THE SAME - Provided are a non-platinum oxygen reduction catalyst for a polymer electrolyte membrane fuel cell and a method for preparing the same. More particularly, an oxygen reduction catalyst in which chelated cobalt is impregnated on a conductive polymer coated on a carbon support and a method for preparing the oxygen reduction catalyst by coating a conductive polymer on a carbon support, impregnating chelated cobalt on the conductive polymer and then treating the same with heat and an acid are disclosed. The platinum-free oxygen reduction catalyst of the present invention has superior oxygen reduction activity and durability with high proportion of pyridinic and graphitic nitrogens on the catalyst surface, and thus can be usefully applied for a polymer electrolyte membrane fuel cell. | 2012-02-02 |
20120028791 | Highly Reactive Photocatalytic Material and Manufacturing Thereof - A method for manufacturing anatase TiO | 2012-02-02 |
20120028792 | METHOD FOR PRODUCING ELECTRODE CATALYST, AND ELECTRODE CATALYST - A method for producing an electrode catalyst, comprising a step of calcining a precursor of the electrode catalyst under conditions under which a second material defined below can change into a carbonaceous material,
| 2012-02-02 |
20120028793 | DUAL-OXIDE SINTER RESISTANT CATALYST - A catalyst material for use at elevated temperatures is provided. The material can include a plurality of fibers and a plurality of particles supported on the fibers. In addition, a porous layer can cover the plurality of particles and allow for process fluid to come into contact with the particles, and yet retard sintering of the particles at elevated temperatures is present. The plurality of fibers can be a plurality of nanofibers which may or may not be oxide nanofibers. The particles can be metallic nanoparticles and the porous layer can be a porous oxide layer. | 2012-02-02 |
20120028794 | CATALYSTS FOR THE PRODUCTION OF HYDROGEN - The invention provides a bio-based feedstock steam reforming catalyst comprising: a modified support; a metal component; and a promoter. The process also provides a method of preparing a bio-based feedstock steam reforming catalyst comprising: providing a support material comprising a transition metal oxide; providing a modifier comprising an alkaline earth element; contacting the support material with the modifier to form a modified support; providing a metal component comprising a Group VIII transition metal; contacting the support material, the modified support or combinations thereof with the metal component to form the steam reforming catalyst; and contacting the modified support, the metal component, the steam reforming catalyst or combinations thereof with a promoter. | 2012-02-02 |
20120028795 | Methods For Producing Nanoparticles Using Palladium Salt And Uses Thereof - The disclosed subject matter is directed to a method for producing nanoparticles, as well as the nanoparticles produced by this method. In one embodiment, the nanoparticles produced by the disclosed method have a high defect density. | 2012-02-02 |
20120028796 | NICOTINE ADSORBENT, QUINOLINE ADSORBENT, BENZOPYRENE ADSORBENT, TOLUIDINE ADSORBENT, AND CARCINOGEN ADSORBENT - A nicotine adsorbent includes a porous carbon material having a specific surface area of 10 m | 2012-02-02 |
20120028797 | METAL CATALYST SUBSTRATE AND ITS MANUFACTURING METHOD - A metal catalyst substrate | 2012-02-02 |
20120028798 | POROUS SUBSTRATES FILLED WITH NANOMATERIALS - A composition comprising: at least one porous carbon monolith, such as a carbon aerogel, comprising internal pores, and at least one nanomaterial, such as carbon nanotubes, disposed uniformly throughout the internal pores. The nanomaterial can be disposed in the middle of the monolith. In addition, a method for making a monolithic solid with both high surface area and good bulk electrical conductivity is provided. A porous substrate having a thickness of 100 microns or more and comprising macropores throughout its thickness is prepared. At least one catalyst is deposited inside the porous substrate. Subsequently, chemical vapor deposition is used to uniformly deposit a nanomaterial in the macropores throughout the thickness of the porous substrate. Applications include electrical energy storage, such as batteries and capacitors, and hydrogen storage. | 2012-02-02 |
20120028799 | GROWTH ENHANCEMENT AND CONTROL OF BACTERIAL AND FUNGAL PLANT DISEASES WITH STREPTOMYCES SCOPULIRIDIS - Methods of controlling plant diseases mediated by bacterial or fungal plant pathogens. The method comprises providing | 2012-02-02 |
20120028800 | NOVEL HERBICIDES - Compounds of Formula (I), wherein the substituents are as defined in claim | 2012-02-02 |
20120028801 | Corn Steep Liquor as A Biostimulant Composition - Aspects of the invention relate to organic biostimulant compositions, including, for example, formulations comprising corn steep liquor (CSL) and water. In certain illustrative embodiments, the organic biostimulant composition further comprises from one to five microbial strains as an inoculant. Another aspect of the invention relates to a method of cultivating plants that comprises the steps of preparing an organic biostimulant composition comprising water and CSL, and applying the organic biostimulant composition through a delivery system to a growth medium supporting plants. | 2012-02-02 |
20120028802 | NITROGEN CONTAINING ISETHIONIC ACID SALT IN REGISTERABLE, STABLE AGRICULTURAL FORMULATIONS - Embodiments of the present invention disclose an agricultural composition that is a registerable, stable agricultural formulation that includes at least one nitrogen containing isethionic acid salt, at least one plant protection product, at least one surfactant and optionally at least one inert ingredient. | 2012-02-02 |
20120028803 | PYRIDAZINONE COMPOUND AND USE THEREOF - A pyridazinone compound represented by formula (I) wherein R | 2012-02-02 |
20120028804 | 3-BIPHENYL-SUBSTITUTED-3-SUBSTITUTED-4-KETOLACTAM AND KETOLACTONE AND THEIR UTILIZATION AS PESTICIDE - The present invention relates to novel 3-biphenyl-substituted, 3-substituted 4-ketolactams and -lactones of the formula (I) | 2012-02-02 |
20120028805 | SYSTEM AND METHOD FOR OPERATING A MAGNETIC RESONANCE IMAGING SYSTEM DURING RAMPING - Systems and methods for operating a magnetic resonance imaging (MRI) during ramping are provided. One method includes reducing pressure in a cryogen vessel of an MRI system during magnet ramping. The method also includes returning pressure in the cryogen vessel to a normal operating pressure level after magnet ramping is complete. | 2012-02-02 |
20120028806 | Method For Planar Implementation Of PI/8 Gate In Chiral Topological Superconductors - Disclosed herein is a topologically protected π/8-gate which becomes universal when combined with the gates available through quasi-particle braiding and planar quasi-particle interferometry. A twisted interferometer, and a planar π/8-gate in CTS, implemented with the help of the twisted interferometer, are disclosed. Embodiments are described in the context of state X (CTS) supported by an ISH, although the concept of a twisted-interferometer is more general and has relevance to all anionic, i.e. quasiparticle systems. | 2012-02-02 |
20120028807 | OXIDE SUPERCONDUCTING COIL, OXIDE-SUPERCONDUCTING-COIL ASSEMBLY, AND ROTATING MACHINE - The invention offers a superconducting coil, which is an oxide superconducting coil | 2012-02-02 |
20120028808 | SUPERCONDUCTOR SUPERIOR IN DEPENDENCY OF CRITICAL CURRENT DENSITY ON MAGNETIC FIELD ANGLE - An oxide superconducting tape comprised of a substrate on which a GdBa | 2012-02-02 |
20120028809 | Textured Powder Wires - A method for fabricating a wire from textured powder includes compressing a powder comprising a plurality of particles into a ribbon. The method further includes encasing the ribbon between two foil sheets to create a sheet of encased ribbon. The method additionally includes rolling the encased ribbon into a substantially cylindrical undrawn wire. The method further includes drawing the undrawn wire to create a substantially cylindrical wire having a diameter less than a diameter of the substantially cylindrical undrawn wire. | 2012-02-02 |
20120028810 | METHOD FOR DEPOSITING OXIDE THIN FILMS ON TEXTURED AND CURVED METAL SURFACES - Method of depositing a layer of oxide of at least one metal element on a curved surface of a textured metal substrate,
| 2012-02-02 |
20120028811 | DEVICE FOR RAPID IDENTIFICATION OF NUCLEIC ACIDS FOR BINDING TO SPECIFIC CHEMICAL TARGETS - The present invention relates to microfluidic chips and their use in SELEX. The microfluidic chip preferably includes a reaction chamber that contains a high surface area material that contains target. One preferred high surface area material is a sol-gel derived material. Methods of making the microfluidic chips are described herein, as are uses of these devices to select aptamers against the target. | 2012-02-02 |
20120028812 | METHOD FOR PRODUCING SECOND-GENERATION LIBRARY - The present invention relates to a method for generating a second-generation library. In a first step, a library of encoded molecules associated with an identifier nucleic acid comprising codons identifying chemical entities that have participated in the formation of the encoded molecule is provided. In a second step, the library is partitioned and encoded molecules having a certain property are selected. Codons of identifiers of selected encoded molecules are subsequently identified, and a second-generation library is prepared using at least some of the chemical entities coded for by the identified codons. The new focussed library may be used for another partition step to select encoded molecules with a certain property. | 2012-02-02 |
20120028813 | Selecting Reference Libraries For Monitoring Of Multiple Zones On A Substrate - A method of configuring a polishing monitoring system includes receiving user input selecting a plurality of libraries, each library of the plurality of libraries comprising a plurality of reference spectra for use in matching to measured spectra during polishing, each reference spectrum of the plurality of reference spectra having an associated index value, for a first zone of a substrate, receiving user input selecting a first subset of the plurality of libraries, and for a second zone of the substrate, receiving user input selecting a second subset of the plurality of libraries. | 2012-02-02 |
20120028814 | OLIGONUCLEOTIDE LIGATION, BARCODING AND METHODS AND COMPOSITIONS FOR IMPROVING DATA QUALITY AND THROUGHPUT USING MASSIVELY PARALLEL SEQUENCING - Described herein is a buffer concentration for highly efficient ligation of two oligonucleotides. The embodiments herein have led to the development of an optimized ligation step used in the sample preparation for sequencing reactions. Further, embodiments herein describe a high-throughput method for sequencing using barcodes or the purpose of multiplexing several samples simultaneously and novel methods for making targeted DNA libraries for re-sequencing on massively parallel next-generation sequencing platforms and for alternatives to gel-purification for recovering the desired templates from small RNA libraries for next generation sequencing. | 2012-02-02 |
20120028815 | NUCLEIC ACID SEQUENCING USING MICROSPHERE ARRAYS - The invention relates to DNA sequencing by synthesis techniques, including those utilizing the detection of pyrophosphate (PPi) generated during the DNA synthesis reaction (pyrosequencing). The methods and compositions utilize biosensor arrays comprising microspheres distributed on a surface. | 2012-02-02 |
20120028816 | METHODS AND SYSTEMS FOR SCREENING FOR AND DIAGNOSING DNA METHYLATION ASSOCIATED WITH AUTISM SPECTRUM DISORDERS - Methods and systems for population screening and diagnostics are provided. In particular methods and systems for population screening of individuals for genetic disorders due to alterations in DNA methylation and for the diagnostic testing for such disorders are provided. | 2012-02-02 |
20120028817 | Methods and Kits for Genome-Wide Methylation of GpC Sites and Genome-Wide Determination of Chromatin Structure - Disclosed are methods and kits for genome-wide methylation of GpC sites and for genome-wide chromatin structural determination. Specifically, the methods and kits of the present invention make possible the simultaneous determination of endogenous DNA methylation state and chromatin architecture across the entire genome. | 2012-02-02 |
20120028818 | MICRO FLUIDIC STRUCTURES - A micro fluidic system includes a substrate, and, provided on said substrate, at least one flow path interconnecting with functional means in which liquid samples can be treated by desired procedures. The flow paths are laid out to form a pattern for the transport of liquid samples to and from said functional means. These flow paths comprise a plurality of micro posts protruding upwards from said substrate, the spacing between the micro posts being small enough to induce a capillary action in a liquid sample applied anywhere within any of said flow paths, so as to force said liquid to move from where said liquid sample was applied. | 2012-02-02 |
20120028819 | METHOD FOR THE DETECTION AND CHARACTERIZATION OF A TOXINOGENIC CLOSTRIDIUM DIFFICILE STRAIN - The invention relates to a method for the detection and characterization of a toxinogenic | 2012-02-02 |
20120028820 | HYBRID SENSOR ARRAY - The present invention provides devices, methods and systems to selectively detect the binding of a molecular species to a biomolecule. In its olfactory sensing application, the hybrid sensor arrays of the present invention provide a high dimensional signature of odorants present that is also readily reversible, together enabling the identification and localization of a source analyte in the presence of the background odorant landscape inherent in a real-world setting. | 2012-02-02 |
20120028821 | PROGRAMMING AND REPROGRAMMING OF CELLS - The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to chimeric animals comprising reprogrammed somatic cells of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells. | 2012-02-02 |
20120028822 | METHODS, FLOW CELLS AND SYSTEMS FOR SINGLE CELL ANALYSIS - A method, flow cell and/or device for increasing the recovery of a limiting analyte in a sample, e.g., for single molecule analysis is disclosed. Methods for preparing a nucleic acid sample from a single cell and capturing nucleic acids on a surface configured for use in or with single molecule analysis are also provided. | 2012-02-02 |
20120028823 | pH MODULATION METHOD TO DETECT LIGAND-RECEPTOR BINDING - The present disclosure relates to detecting receptor-ligand binding by measuring local pH modulation using a pH-sensitive fluorophore. | 2012-02-02 |
20120028824 | METHOD FOR THE IN VITRO DIAGNOSIS OF STROKE - A method for the in vitro diagnosis of stroke and transient ischemic attack (TIA) in an individual, comprising the following steps: (a) measuring the level of proBNP(1-108), or of fragments of proBNP(1-108) comprising a RAPRSP sequence (SEQ ID NO: 1), in a biological sample of the individual; (b) measuring the level of nucleoside diphosphate kinase A (NDKA) in a biological sample of the individual; (c) comparing the level of proBNP(1-108), or of fragments of proBNP(1-108), and the level of NDKA, with one or several cut-off values; and (d) determining therefrom whether a stroke or a TIA has occurred in the individual. | 2012-02-02 |
20120028825 | GALECTIN-1 (GAL1) AS A BIOMARKER FOR DIFFERENTIAL DIAGNOSIS OF OSTEOSARCOMA AND CHONDROSARCOMA - The present invention relates to a method for differential diagnosis of osteosarcoma and chondrosarcoma, especially chondroblastic osteosarcoma and conventional chondrosarcoma, in a patient comprising a step consisting of detecting galectin-1 (GAL1) expression in a bone sample obtained from said patient. | 2012-02-02 |
20120028826 | Methods and Compositions for Analysis of Nucleic Acids - Compositions and methods for analysis of nucleic acids are disclosed. Targets are hybridized to arrays having features that include pairs of co-localized probes within features. The probe pairs may include a first probe type that is oriented so that the 5′ end is free and the 3′ end is attached to the support and a second probe type that is oriented so that the 3′ end is free for extension and the 5′ end is attached to the support. The probes of a feature are complementary to different regions of the same target sequence so they can simultaneously hybridize to a single target with a gap or nick between. The gap may be filled by extension and ligation or ligation. | 2012-02-02 |
20120028827 | METHOD FOR DETERMINING A RISK, FOR A SUBJECT, OF SUFFERING FROM ATOPIC DERMATITIS OR SEVERITY OF ATOPIC DERMATITIS FOR A SUBJECT SUFFERING FROM ATOPIC DERMATITIS AND METHOD FOR USING A SINGLE-NUCLEOTIDE POLYMORPHISM RS12313273 AS A BIOMARKER FOR DETERMINING THE DEVELOPMENT OR SEVERITY OF ATOPIC DERMATITIS - The invention provides a method for determining a risk, for a subject, of suffering from atopic dermatitis, including: obtaining a biosample of the subject; detecting the presence of the single-nucleotide polymorphism rs12313273 (C/T) at position 30881 of the ORAI1 gene (SEQ ID No.: 1) in the biosample; and determining the risk, for the subject, of suffering from atopic dermatitis, wherein the presence of a C allele or genotype CC of the single-nucleotide polymorphism rs12313273 (C/T) indicates that the subject is at increased risk for suffering from atopic dermatitis. | 2012-02-02 |
20120028828 | Fluorescent Methods and Materials for Directed Biomarker Signal Amplification - Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule. | 2012-02-02 |
20120028829 | ANTI-HEDGEHOG ANTIBODIES - The invention relates to anti-hedgehog antibodies, their use in the detection of hedgehog expression in tissue, and to the use of such detection in the treatment of cancer. | 2012-02-02 |
20120028830 | MICROFLUIDIC DEVICE FOR SIMULTANEOUSLY CONDUCTING MULTIPLE ANALYSES - Provided is a rotatable microfluidic device for conducting simultaneously two or more assays. The device includes a platform which can be rotated, a first unit which is disposed at one portion of the platform and detects a target material from a sample using surface on which a capture probe selectively binds to the target material is attached, and a second unit which is disposed at another portion of the platform and detects a target material included in the sample by a different reaction from the reaction conducted in the first unit. | 2012-02-02 |
20120028831 | MiR-29-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML) - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML). The invention also provides methods of identifying anti-AML agents. | 2012-02-02 |
20120028832 | MiR-182-, miR-191, miR-199a-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML) - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML). | 2012-02-02 |
20120028833 | MiR-25-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML) - The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML). The invention also provides methods of identifying anti-AML agents. | 2012-02-02 |
20120028834 | COLOR ENCODED MAGNETIC STRUCTURE - Provided is a color encoding method including providing a composition including a liquid medium and magnetic nanoparticles dispersed in the liquid medium; applying a magnetic field to the composition to align the magnetic nanoparticles; and applying a patterned energy source to the composition to solidify the composition, wherein more than one region of the composition are sequentially solidified with varying magnetic field strength to fix a plurality of color codes | 2012-02-02 |
20120028835 | SECERNIN-1 AS A MARKER FOR CANCER - Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a method for assessing cancer from a liquid sample derived from an individual by measuring SCRN1 in the sample. Measurement of SCRN1 can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery. | 2012-02-02 |
20120028836 | USE OF PROTEIN SATB2 AS A MARKER FOR COLORECTAL CANCER - The invention provides new methods, means and uses in connection with detection, characterization and prognosis of colo-rectal cancer, via the identification of the SATB2 protein as a marker for this cancer type. | 2012-02-02 |
20120028837 | RAPID SCREEN FOR REPRODUCTIVE TOXICANTS - Disclosed herein are methods to assess the biological safety of an agent. The method involves contacting one or more test agents to a culture of | 2012-02-02 |
20120028838 | Quantification of Gene Expression - The present invention relates to a method for measuring the amount of a target nucleic acid in a sample using a standard which is designed to have one base difference compared with the gene of interest or a “target nucleic acid sequence.” Use of such standard in combination with a method of “enhancing” the difference in the standard and the test nucleic acid sample using, for example, a base extension reaction carried right at the mutation site allowing amplification of the standard and target nucleic acids with the same efficiency and facilitating quantification of the target nucleic acid. Thereafter a means of quantifying the “enhanced” standard and target nucleic acid samples is used to determine the amount of the target nucleic acid. In the preferred embodiment, the quantification means is Mass Spectrometry. | 2012-02-02 |
20120028839 | SYNTHETIC IMMUNOGLOBULIN DOMAINS WITH BINDING PROPERTIES ENGINEERED IN REGIONS OF THE MOLECULE DIFFERENT FROM THE COMPLEMENTARITY DETERMINING REGIONS - Libraries of immunoglobulins which each have one or more amino acid modifications in at least one structural loop region of such immunoglobulins, where the modified loop region specifically binds to an epitope of an antigen to which an unmodified immunoglobulin does not significantly bind. | 2012-02-02 |