| 05th week of 2014 patent applcation highlights part 50 |
| Patent application number | Title | Published |
|---|
| 20140031184 | Tool Holder for Receiving and Locking a Tool Taper on a Tool Magazine, Unlocking Device, and Tool Magazine - The present disclosure relates to a tool holder to receive and lock a tool taper on a tool magazine, an unlocking device to unlock a tool taper that is received and is locked in a tool holder of this type, and a tool magazine for a machine tool comprising one or more tool holders of this type and an unlocking device of this type. | 2014-01-30 |
| 20140031185 | WOOD CHIPPER FEED ROLLER - A feed system that is configured to more effectively grab and pull brush and tree materials into a chipper is provided. The system of the present disclosure is configured such that a large, heavy tree trunk can be continuously pulled into the chipper. The system includes two feed rollers one above the other in an offset arrangement. | 2014-01-30 |
| 20140031186 | Reinforced Bag - A bag has a reinforcement that is configured in a predetermined manner for reinforcing at least a portion of the bag. One or more predetermined areas of the bag may be reinforced. The bag may have one or more layers, and may be reinforced by placing and affixing reinforcing media in selected areas. The nature of the reinforcing media—its dimensions and structural properties—may be selected with respect to targeted uses of the bag. The bag may be subjected to one or more types of potentially failure-causing strain (e.g. bending, twisting, puncture, tensile, compression) during the useful life of the bag. For example, the bag may be stressed during filling the bag with product, top sealing, conveying by hand or machine, loading and stacking, transportation, storage, selling and final use by the consumer. | 2014-01-30 |
| 20140031187 | SACK PAPER WITH VAPOUR BARRIER - The present invention provides a method of forming a coating on a porous sheet, comprising the steps of: providing a porous sheet and a dispersion comprising at least one polyolefin; applying said dispersion on at least one surface of said sheet; and optionally, heating said sheet to a temperature above the melting temperature of said at least one polyolefin. Moreover, the present invention relates to methods for manufacturing single and two ply sacks and the use of at least one polyolefin as a water vapour barrier coating on a material suitable for a ply of a sack. | 2014-01-30 |
| 20140031188 | METHOD AND APPARATUS FOR ERECTING PART OF A CONTAINER - The invention relates to a method and apparatus for erecting part of a container, specifically containers referred to as “trays” in the art. The method includes using a mandrel to fold four walls ( | 2014-01-30 |
| 20140031189 | METHOD OF HALF-CUT CUTOUT PROCESSING OF LABEL PAPER - A method of half-cut cutout processing of label paper | 2014-01-30 |
| 20140031190 | CREASING ACCESSORY AND METHOD OF PROVIDING A CREASE IN A SUBSTRATE - The invention relates to an accessory used to crease substrate ( | 2014-01-30 |
| 20140031191 | CENTRIFUGE - A centrifuge including: a rotor configured to hold a sample and configured to be detachably mounted, a rotation chamber accommodating the rotor, a plurality of motors configured to be rotationally driven by three-phase AC power, and a control device configured to control centrifuging operation, wherein one of the plurality of motors is a centrifuge motor configured to rotate the rotor, and the control device is configured to change distribution of power supplied to the centrifuge motor and power supplied to another motor of the plurality of motors during one operation. | 2014-01-30 |
| 20140031192 | GLASS SUBSTRATE FOR DISPLAY AND DISPLAY - A glass substrate for a display, which is formed of a glass having a light weight and having high refinability with decreasing environmental burdens, the glass comprising, by mass %, 50 to 70% of SiO | 2014-01-30 |
| 20140031193 | PHOTOCATALYTIC METHODS FOR PREPARATION OF ELECTROCATALYST MATERIALS - The invention relates to methods and structures of metal particles on a support material, including platinum-containing nanoparticles on a carbon support. Such materials can be used as electrocatalysts, for example as improved electrocatalysts in polymer electrolyte membrane fuel cells (PEM-FCs). | 2014-01-30 |
| 20140031194 | Integral Synthesis Gas Conversion Catalyst Extrudates and Methods For Preparing and Using Same. - Methods for preparing integral synthesis gas conversion catalyst extrudates including an oxide of a Fischer-Tropsch (FT) metal component and a zeolite component are disclosed. The oxide of the FT metal component is precipitated from a solution into crystallites having a particle size between about 2 nm and about 30 nm. The oxide of the FT metal component is combined with a zeolite powder and a binder material, and the combination is extruded to form integral catalyst extrudates. The oxide of the FT metal component in the resulting catalyst is in the form of reduced crystallites located outside the zeolite channels. No appreciable ion exchange of FT metal occurs within the zeolite channels. The acid site density of the integral catalyst extrudate is at least about 80% of the zeolite acid site density. | 2014-01-30 |
| 20140031195 | ANIONIC GOLD-HYDROXO COMPLEX SOLUTION AND PROCESS FOR PRODUCING MATERIAL LOADED WITH GOLD NANOPARTICLES - The method for producing a material loaded with gold nanoparticles, includes: impregnating a carrier with an anionic gold-hydroxo complex solution including a transparent solution that has a pH of not lower than 8, does not contain a halide anion, and contains a conjugate base of a weak acid not coordinated to gold and an anionic hydroxo complex of trivalent gold having a square planar molecular geometry whose at least one ligand is OH | 2014-01-30 |
| 20140031196 | FENTON REACTION CATALYST PRODUCED USING REDUCING ORGANIC SUBSTANCE AS RAW MATERIAL - To develop a Fenton reaction catalyst that can maintain divalent iron stably for a long period of time, can utilize trivalent iron or metallic iron, which is an inexpensive iron-supplying source, by converting into divalent iron, and is harmless to the human body and the environment, provided is a Fenton reaction catalyst, including, as an active component, a reaction product obtained by mixing a specific reducing organic substance (e.g., ascorbic acid, a polyphenol-containing plant component, or a plant dry distillation liquid component) with an iron-supplying source at a predetermined ratio in the presence of water. Also provided are a sterilization method, a pollutant degradation method, and a luminescence method based on chemiluminescence, which involve using the Fenton reaction catalyst. | 2014-01-30 |
| 20140031197 | Catalyst Materials - A catalyst material including a catalyst carrier including a porous alumina support and a hindrance layer on the alumina support, the hindrance layer comprising one or more barium sulfate, strontium sulfate, zirconium sulfate, and calcium sulfate is described. The catalyst carrier further includes a rare earth oxide. The catalyst material can further comprise a platinum group metal oxide. The hindrance layer may prevent the rare earth oxide from forming a complex with the support. The catalyst material is useful for methods and systems of abating pollutants from automotive exhaust gas. | 2014-01-30 |
| 20140031198 | PROCESS FOR PREPARING OLEFINS FROM SYNTHESIS GAS USING A COBALT AND MANGANESE CONTAINING CATALYST - The invention relates to a process for preparing a supported catalyst, wherein the catalyst contains cobalt, manganese and a third element selected from the group consisting of aluminium, gallium, indium, thallium, tin, lead and bismuth, and is prepared by co-precipitation of a manganese salt and a cobalt salt on a support, followed by impregnation with a salt of the third element. Further, the invention relates to the catalyst so obtained. | 2014-01-30 |
| 20140031199 | METHANE SYNTHESIS CATALYST PREPARATION METHOD AND CATALYST PRECURSOR - The present invention relate to a methane synthesis catalyst preparation method, comprising a preparation step for a catalytic body and a prereduction step. The prereduction step comprises: calcining the catalytic body to form a nickel aluminate spinel-containing catalyst precursor; and prereducing the catalyst precursor to acquire the methane synthesis catalyst. The catalyst prepared in the preparation method can be used in high-temperature and high liquid-to-gas ratio conditions, shows performance stability, and obviates the need for a further step of high-temperature reduction during vehicle operation. Also provided is the methane synthesis catalyst precursor. The catalyst precursor contains nickel aluminate spinel. | 2014-01-30 |
| 20140031200 | CO2 REFORMING CATALYST, METHOD OF PREPARING THE SAME, AND METHOD OF REFORMING CO2 | 2014-01-30 |
| 20140031201 | CATALYST - A catalyst comprising a plurality of catalyst gauzes that are arranged in series is provided. Each catalyst gauze is made of a first noble-metal-containing wire and a second noble-metal-containing wire which is embedded in the catalyst gauze and which gives the catalyst gauze a preferential direction. The catalyst gauzes according to the invention are arranged in series such that the angles between the preferential directions of neighboring catalyst gauzes are between 0° and 180°. The catalyst ensures a product yield that is reproducible over time and has a long service life. | 2014-01-30 |
| 20140031202 | CATALYST - A catalyst comprising a plurality of catalyst gauzes that are arranged in series is provided. Each catalyst gauze is made of a first noble-metal-containing wire and a second noble-metal-containing wire which is embedded in the catalyst gauze and which gives the catalyst gauze a preferential direction. The catalyst gauzes according to the invention are arranged in series such that the angles between the preferential directions of neighboring catalyst gauzes ranges from 0° to 180°. The catalyst ensures a product yield that is reproducible over time and has a long service life. | 2014-01-30 |
| 20140031203 | WATER-ABSORBENT RESIN, ABSORBENT BODY AND ABSORBENT ARTICLE - The present invention provides a novel water-absorbent resin desirable for use as a hygienic material and the like, and an absorbent material and absorbent article using the water-absorbent resin; the water-absorbent resin having a high gel strength that prevents a reduction in liquid permeation rate by suppressing gel blocking during absorption, and an excellent water-retention capacity at the same time. | 2014-01-30 |
| 20140031204 | ACTIVE COMPOUND COMBINATIONS - The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) 2,6-dichloro-N-[3-chloro-5-(trifluoromethyl)-2-pyridylmethyl]benzamide (CAS-No 239110-15-7, common name fluopicolide) of formula (I) and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively combating undesirable microorganisms of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. | 2014-01-30 |
| 20140031205 | Composition Containing a Pesticide and a Vinylimidazol Terpolymer - The present invention relates to an agrochemical composition containing a pesticide and a copolymer, which contains in polymerized form at least 20 wt % vinylimidazol and/or a quaternized vinylimidazol, an acidic comonomer, and a hydrophobic comonomer, which comprises C | 2014-01-30 |
| 20140031206 | Substituted pyrimidinium compounds for combating animal pests - Substituted imine compounds of formula (I), | 2014-01-30 |
| 20140031207 | Pesticidal Compound Mixtures - The present invention relates to novel pesticidal compositions comprising Hither as component A: clothianidin, as component B: ipconazole Or as component A: clothianidin, as component B: ipconazole as component C: metalaxyl that show surprisingly good insecticidal, acaricidal, nematicidal and fungicidal activities. In particular, these compositions are suited for the treatment of seed. | 2014-01-30 |
| 20140031208 | Use of substituted dithiine-tetracarboximides for combating phytopathogenic fungi - The present invention relates to the use of dithiine-tetracarboximide compounds of formula I as defined in the description, and the N-oxides, and salts thereof for combating harmful fungi and seed coated with at least one such compound. The invention also relates to novel dithiine-tetracarboximides, processes and intermediates for preparing these compounds and also to compositions comprising at least one such compound. | 2014-01-30 |
| 20140031209 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2- -CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND A SULFONYLAMINOCARBONYLTRIAZOLINONE - A herbicidal composition containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031210 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND CLOMAZONE - Provided herein are synergistic herbicidal compositions containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031211 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND A DI-METHOXY-PYRIMIDINE AND DERIVATIVES THEREOF - A synergistic herbicidal composition containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031212 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND 4-HYDROXYPHENYL-PYRUVATE DIOXYGENASE (HPPD) INHIBITORS - Provided herein are synergistic herbicidal compositions containing and methods of controlling undesirable vegetation utilizing (a) a compound of formula (I): | 2014-01-30 |
| 20140031213 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND IMIDAZOLINONES - A synergistic herbicidal composition containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031214 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND SYNTHETIC AUXIN HERBICIDES - Provided herein are herbicidal compositions containing and methods for controlling undesirable vegetation utilizing (a) a compound of formula (I): | 2014-01-30 |
| 20140031215 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2- -CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND BROMOBUTIDE, DAIMURON, OXAZICLOMEFONE OR PYRIBUTICARB - Provided herein are synergistic herbicidal compositions containing (a) a compound of | 2014-01-30 |
| 20140031216 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND HALOSULFURON, PYRAZOSULFURON AND ESPROCARB - Provided herein are synergistic herbicidal compositions containing and methods of controlling undesirable vegetation utilizing
| 2014-01-30 |
| 20140031217 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2- -CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND AUXIN TRANSPORT INHIBITORS - Provided herein are herbicidal composition containing and method of controlling undesirable vegetation utilizing (a) a compound of formula (I): | 2014-01-30 |
| 20140031218 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND CERTAIN SULFONYLUREAS - Provided herein are synergistic herbicidal compositions comprising (a) a compound of formula (I): | 2014-01-30 |
| 20140031219 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2- -CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND MICROTUBULE INHIBITING HERBICIDES - Provided herein are synergistic herbicidal compositions containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031220 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND A PROTOPORPHYRINOGEN OXIDASE INHIBITOR - Provided herein are synergistic herbicidal compositions containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031221 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND CELLULOSE BIOSYNTHESIS INHIBITOR HERBICIDES - Provided herein are synergistic herbicidal compositions containing and methods for controlling undesirable vegetation utilizing
| 2014-01-30 |
| 20140031222 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2- -CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND CERTAIN PS II INHIBITORS - Provided herein are synergistic herbicidal compositions containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031223 | HERBICIDAL COMPOUNDS - The present invention relates to novel herbicidal compounds of Formula (I), or an agronomically acceptable salt of said compound wherein R | 2014-01-30 |
| 20140031224 | SAFENED HERBICIDAL COMPOSITIONS INCLUDING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2- -CARBOXYLIC ACID OR A DERIVATIVE THEREOF FOR USE IN RICE - A safened herbicidal composition for use in rice comprising a herbicidally effective amount of (a) a compound of formula (I): | 2014-01-30 |
| 20140031225 | SAFENED HERBICIDAL COMPOSITIONS INCLUDING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2- -CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND METHODS FOR THEIR USE - A safened herbicidal composition for use, for example, in wheat or barley, comprising a herbicidally effective amount of (a) a compound of formula (I): | 2014-01-30 |
| 20140031226 | COMPOSITIONS AND METHODS FOR PROVIDING MICRONUTRIENTS TO CROPS - Aqueous compositions containing glyphosate along with manganese phosphite and/or zinc phosphite are suitable for providing micronutrients for plant health and weed control without concern of chelation of the micronutrient metal by the glyphosate. | 2014-01-30 |
| 20140031227 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND GLYPHOSATE OR GLUFOSINATE - Provided herein are synergistic herbicidal compositions containing and method for controlling undesirable vegetation utilizing (a) a compound of formula (I): | 2014-01-30 |
| 20140031228 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND ACETYL-CoA CARBOXYLASE (ACCASE) INHIBITORS - Provided herein are synergistic herbicidal compositions containing and methods utilizing (a) a compound of formula (I): | 2014-01-30 |
| 20140031229 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND TRIAZOLOPYRIMIDINE SULFONAMIDES - Provided herein are synergistic herbicidal compositions containing (a) a compound of formula (I): | 2014-01-30 |
| 20140031230 | AUXIN BIOSYNTHESIS INHIBITOR - An object of the present invention is to provide an auxin biosynthesis inhibitor superior to L-AOPP. The object can be attained by a compound represented by general formula (I): wherein, R | 2014-01-30 |
| 20140031231 | FORMULATIONS OF CLOMAZONE - New formulations of clomazone are provided, as well as new methods for making formulations of clomazone. The new formulations provide improved efficacy, decreased volatility, and/or increased loading of clomazone over the clomazone formulations in the prior art. | 2014-01-30 |
| 20140031232 | DISPERSIBLE HERBICIDAL COMPOSITIONS AND METHODS OF USE - Herbicidal dispersible concentrates include an herbicide and substantially water miscible amide-based solvents. Such concentrates may be diluted in water and used in methods to control weeds. | 2014-01-30 |
| 20140031233 | METHOD FOR PROMOTING PLANT GROWTH - Disclosed is a method for promoting the growth of a plant, comprising treating the plant with an effective amount of a compound represented by the following formula ( | 2014-01-30 |
| 20140031234 | METHOD OF ACTIVATING IMMUNE RESPONSE IN PLANTS - A method of enhancing plant immunity is provided. The method comprises the step of administering to a plant a small molecule that binds to NPR1, or a functionally equivalent homolog thereof, that disrupts the interaction between N-terminal BTB/POZ domain and the C-terminal transactivation domain of NPR1. A method of screening for small molecule compounds that enhance plant immunity is also provided. | 2014-01-30 |
| 20140031235 | SUPERCONDUCTING COIL, SUPERCONDUCTING MAGNET, AND METHOD FOR MANUFACTURING SUPERCONDUCTING COIL - An inner circumferential portion is formed by winding one of first and second superconducting wires each having a band shape. An outer circumferential portion is formed by winding the other of the first and second superconducting wires around the inner circumferential portion. A welding portion joins the first and second superconducting wires to each other by welding between the inner circumferential portion and the outer circumferential portion. The first superconducting wire is higher in strength than the second superconducting wire. The second superconducting wire is smaller in thickness than the first superconducting wire. | 2014-01-30 |
| 20140031236 | OXIDE SUPERCONDUCTOR, ORIENTED OXIDE THIN FILM, AND METHOD FOR MANUFACTURING OXIDE SUPERCONDUCTOR - According to one embodiment, an oxide superconductor includes an oriented superconductor layer and an oxide layer. The oriented superconductor layer contains fluorine at 2.0×10 | 2014-01-30 |
| 20140031237 | Methods of enriching for and identifying polymorphisms - The invention encompasses methods for enriching for and identifying a polymorphism within a nucleic acid sample either by separating a subset of a nucleic acid sample or by selectively replicating a subset of a nucleic acid sample such that the polymorphism is contained within a nucleic acid population with reduced complexity, and then identifying the polymorphism within the enriched nucleic acid sample. Methods also are disclosed for enriching for and identifying a polymorphism by contacting a nucleic acid sample that includes a subset of nucleic acid molecules having a sequence that binds to a sequence-specific binding activity with a molecule having a sequence-specific binding activity under conditions which permit specific binding, such that the subset of nucleic acid molecules bound to the activity is enriched for nucleic acid molecules having the sequence recognized by the sequence-specific binding activity, and detecting a polymorphism with respect to a reference sequence in the subset of nucleic acid molecules. | 2014-01-30 |
| 20140031238 | ALTERNATIVE NUCLEOTIDE FLOWS IN SEQUENCING-BY-SYNTHESIS METHODS - A method for sequencing a polynucleotide strand by using sequencing-by-synthesis techniques. To address the problem of incomplete extension (IE) and/or carry forward (CF) errors that can occur in sequencing-by-synthesis reactions, an alternative flow ordering of dNTPs is used. In contrast to conventional flow orderings, the dNTPs are flowed in an ordering that is not a continuous repeat of an ordering of the four different dNTPs. This alternate flow ordering may reduce the loss of phasic synchrony in the population of template polynucleotide strands that result from IE and/or CF errors. | 2014-01-30 |
| 20140031239 | METHOD OF SEQUENCING - The present invention provides a method of sequencing a single polynucleotide in which the nucleotide base and/or probe which is incorporated during sequencing is labelled with a bead which is detected to identity the base and/or probe which has bound to the single polynucleotide. Particularly, the detection of the bead may be carried out using an apparatus comprising a surface provided with a means for detecting a bead e.g. with one or more light sensitive elements. | 2014-01-30 |
| 20140031240 | TM-ENHANCED BLOCKING OLIGONUCLEOTIDES AND BAITS FOR IMPROVED TARGET ENRICHMENT AND REDUCED OFF-TARGET SELECTION - The invention is directed to modified oligonucleotide compositions and methods for selectively reducing unwanted nucleic acid contaminants and enriching for desired nucleic acid targets from complex genomic nucleic acid mixtures for sequencing applications. The modified oligonucleotide compositions include one or more modified groups that increase the T | 2014-01-30 |
| 20140031241 | PAIRED END BEAD AMPLIFICATION AND HIGH THROUGHPUT SEQUENCING - The present invention is related to genomic nucleotide sequencing. In particular, the invention describes a paired end sequencing method that enables the sequencing of unique read pairs by co-localizing both 5′ ends on a single emulsion polymerase chain reaction bead. The method may use a customized forked adaptor primer pair that is compatible with massively parallel sequencing techniques. The compositions and methods disclosed herein contemplate sequencing complex genomes, amplified genomic regions, as well as detecting chromosomal structural rearrangements. | 2014-01-30 |
| 20140031242 | METHOD FOR DISCOVERING PHARMACOGENOMIC BIOMARKERS - The present invention relates to a method of discovering pharmacogenomic biomarkers that are correlated with varied individual responses (efficacy, adverse effect, and other end points) to therapeutic agents. The present invention provides a mean to utilize archived clinical samples to perform genome-wide association study in order to identify novel pharmacogenomic biomarkers. The newly discovered biomarkers can then be developed into companion diagnostic tests which can help to predict drug responses and apply drugs only to those who will be benefited, or exclude those who might have adverse effects, by the treatment. | 2014-01-30 |
| 20140031243 | MULTIPLEX DETECTION OF MOLECULAR SPECIES IN CELLS BY SUPER-RESOLUTION IMAGING AND COMBINATORIAL LABELING - Methods and systems are provided for creating molecular barcodes or indicia for cellular constituents within single cells and for resolving such barcodes or indicia with super-resolution technologies such as super-resolution microscopy. By this approach, numerous molecular species that can be measured simultaneously in single cells. It has been demonstrated that multiple mRNA transcripts can be labeled with a spatially ordered sequence of fluorophores, and that barcodes can be resolved. In addition, alternative splicing events can be characterized by identifying and quantifying mRNA isoforms in an individual cell. | 2014-01-30 |
| 20140031244 | OPTIMIZED PROBE SELECTION METHOD - The present invention provides methods for optimizing oligonucleotide hybridization probes for use in basic and clinical research. Specifically, the invention involves hybridizing serially diluted genomic sample to the oligonucleotide probes on the array, such that a signal intensity is produced for each of the probes; computationally identifying optimized probes which exhibit signal intensities that correspond to the serial dilutions of genomic sample and are reproducibly strong relative to non-optimized probes. | 2014-01-30 |
| 20140031245 | ALZHEIMER'S DISEASE-SPECIFIC ALTERATIONS OF THE ERK1/ERK2 PHOSPHORYLATION RATIO-ALZHEIMER'S DISEASE-SPECIFIC MOLECULAR BIOMARKERS (ADSMB) - The present invention relates to methods of diagnosing Alzheimer's Disease as well as to methods of confirming the presence or absence of Alzheimer's Disease in a subject. The present invention is also directed to methods of identifying a lead compound useful for the treatment of Alzheimer's Disease by contacting non-Alzheimers cells with an amyloid beta peptide, stimulating the cells with a protein kinase C activator, contacting the cells with a test compound, and determining the value of an Alzheimer's Disease-specific molecular biomarker. The present invention is also directed to methods of diagnosing Alzheimer's Disease in a subject by detecting alterations in the ratio of specific phosphorylated MAP kinase proteins in cells after stimulation with a protein kinase C activator. The Alzheimer's Disease-specific molecular biomarkers disclosed herein are useful for the diagnosis of Alzheimer's Disease, monitoring the progression of Alzheimer's Disease in a subject and in screening methods for the identification of compounds for treating or preventing Alzheimer's Disease. The invention is also directed to kits containing reagents for the detection and diagnosis of the presence or absence of Alzheimer's Disease using the Alzheimer's Disease-specific molecular biomarkers disclosed herein. | 2014-01-30 |
| 20140031246 | CIRCULATING MICRORNAS ARE BIOMARKERS OF VARIOUS DISEASES - The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of biomarkers to diagnose and monitor various diseases such as cancer. | 2014-01-30 |
| 20140031247 | METHODS AND COMPOSITIONS FOR GAMMA-SECRETASE ASSAY - Presented herein are polypeptide substrates based on Notch polypeptides, assay methods based on the use of these substrates, and screening methods directed toward identifying inhibitors of γ-secretase activity. The assay methods and the screening methods are adapted for use in high throughput multi-well plate assay apparatuses. In many embodiments the substrate polypeptides are labeled for ease of detection, and/or may bind specific ligands that themselves are labeled. Generally the labels promote high specificity as well as high sensitivity of detection. These features render the assay and screening methods that employ the labeled substrates especially suited for use in high throughput assay formats. | 2014-01-30 |
| 20140031248 | Detection of Amplification Products - Compositions and methods are provided for quantitative detection of amplification products, the methods being suitable for multiplexing. A first oligonucleotide that includes a primer sequence for priming an amplification reaction and also is labeled with a fluorescent label or quencher is mixed with a second oligonucleotide which has a sequence suitable for hybridizing to a portion of the first oligonucleotide and has a fluorescent label if the first oligonucleotide has a quencher or a quencher if the first oligonucleotide has a fluorescent label; and a third nucleotide which includes some or all the primer sequence contained in the first oligonucleotide but is not labeled, the first and third oligonucleotide being combined in a molar ratio of 2.8 to 8.2. | 2014-01-30 |
| 20140031249 | MULTIPLEX MEASURE OF ISOTYPE ANTIGEN RESPONSE - Described are methods for simultaneous detection and quantifying multiple target analytes, including immunoglobulin isotypes and sub-classes, single and multiple protein antibodies within a test sample contained in a single reaction vessel. Such methods use reaction wells as on a multi-well plate, each single well comprising microarrays of calibration spots, each having a predetermined quantity of a target analyte; and capture spots, each having multiple agent antibodies, including isotypes and subclasses that specifically bind the target analytes. The captured analytes and the calibration spots are detected with fluorescently labeled antibodies specific for each different target analyte. Calibration spots generate calibration curves for quantitative determinations of different target analytes. Also described are methods for detecting and quantifying biomarkers, therapeutic proteins and patient derived antibodies; the use of secondary reagents to determine immunoglobulin classes Ig G, A, M, E and sub-classes including IgG1, IgG2, IgG3, IgG4 and IgA. The intensity of each fluorescent signal allows measurement of a specific immune response to a therapeutic protein and associated analytes; interrogates neutralizing effects of patient antibodies on therapeutic proteins, e.g., insulin therapy. | 2014-01-30 |
| 20140031250 | Biomarkers of Cancer - Methods for diagnosing cancer based on detecting the presence of increased levels of expression of satellite repeats and/or Line-1. | 2014-01-30 |
| 20140031251 | METHODS OF CLASSIFYING HUMAN SUBJECTS WITH REGARD TO CANCER PROGNOSIS - In one aspect, methods, markers, and expression signatures are disclosed for assessing the degree to which a cell sample has epithelial cell-like properties or mesenchymal cell-like properties. In another aspect, methods are provided for predicting cancer patient prognosis based on whether the cancer is classified as having a high or low EMT Signature Score. | 2014-01-30 |
| 20140031252 | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF INLAMMATORY DISORDERS AND FIBROTIC DISEASE - Compositions and methods are disclosed for the treatment and diagnosis of inflammatory diseases and disorders, including pulmonary diseases and fibrotic disorders, including COPD. The invention also provides means for predicting an increased risk of progression of COPD symptoms. | 2014-01-30 |
| 20140031253 | Protein Detection Using Three-Dimensional Carbon Microarrays - The potential of aptamers as ligand binding molecule have opened new avenues in the development of biosensors for proteins, such as cancer oncoproteins. Disclosed herein is a label-free detection strategy using signaling aptamer/protein binding complex for proteins, such as platelet-derived growth factor (PDGF-BB) oncoprotein. The detection mechanism is based on the release of a fluorophore (e.g., TOTO intercalating dye) from the target binding aptamer's stem structure when it captures the protein, e.g., PDGF. Amino-terminated three-dimensional carbon microarrays fabricated by pyrolyzing patterned photoresist are used as a detection platform. The sensor showed near linear relationship between the relative fluorescence difference and protein concentration even in the sub-nanomolar range with an excellent detection limit of 5 pmol. This detection strategy is promising in a wide range of applications in the detection of cancer biomarkers and other proteins. | 2014-01-30 |
| 20140031254 | DETECTION OF CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH ENDOMETRIAL CANCER - The methods and compositions described herein address the need for diagnostic method that could be offered to women during yearly checkups to allow for early detection, diagnosis and classification, and treatment of endometrial cancer. In addition, these methods and compositions address the current need for improving diagnostic accuracy of biopsy procedures in symptomatic patients. | 2014-01-30 |
| 20140031255 | METHOD FOR IDENTIFYING NEONATES AT RISK FOR NECROTIZING ENTEROCOLITIS - The invention provides a method for identifying a neonatal subject at risk for NEC, said method comprising (a) profiling the microbiota in a sample from the GI tract of said subject prior to a conclusive diagnosis of NEC and/or prior to full onset of NEC, (b1) comparing said profile to a standard microbiota profile obtained from corresponding samples from neonatal subjects with NEC or subjects which later developed NEC and determining the degree of correlation between said profile and the standard profile(s), and/or (b2) comparing said profile to a standard microbiota profile obtained from corresponding samples from neonatal subjects which did not develop NEC and determining the degree of correlation between said profile and the standard profile, and (c) identifying the subject as being at risk of NEC if significant correlation is observed in (b1) and/or significant correlation is not seen in (b2). An oligonucleotide probe set for use in the method of the invention, and kits containing the same, are also provided. | 2014-01-30 |
| 20140031256 | METHODS OF DETECTING THERAPEUTIC EXOSOMES - We describe a method of detecting a therapeutic exosome, the method comprising detecting an activity of an exosome. The activity may be selected from the group consisting of: (a) immunodulatory activity; (b) complement inhibition activity; (c) proteasome activity; (d) glycolytic enzyme activity; (e) anti-oxidative activity; (f) extracellular matrix (ECM) modifying activity; (g) NT5E (CD73) ecto-5′-ectonucleotidase activity; (h) ion homeostasis activity; and (i) chaperone activity. If the exosome is detected as having one or more such activities, the exosome is likely to comprise a therapeutic exosome having therapeutic activity. | 2014-01-30 |
| 20140031257 | METHODS AND BIOMARKERS FOR DETECTION OF GASTROINTESTINAL CANCERS - The present invention relates to methods and biomarkers (e.g., epigenetic biomarkers) for detection of gastrointestinal cancers (e.g., colorectal cancer, gastric cancer, pancreatic cancer, liver cancer, cancer of the gall bladder and/or bile ducts (e.g., cholangiocarcinoma)) in biological samples (e.g., tissue samples, stool samples, blood samples, plasma samples, cell samples, gall samples, bile samples, serum samples). | 2014-01-30 |
| 20140031258 | SERUM-BASED MIRNA MICROARRAY AND ITS USE IN DIAGNOSIS AND TREATMENT OF BARRETT'S ESOPHAGUS (BE) AND ESOPHAGEAL ADENOCARCINOMA (EAC) - Robust and reliable molecular diagnostic screening tools for early detection of esophageal and gastrointestinal tract cancers and pre-cancerous lesions, such as Barrett's Esophagus, and esophageal adenocarcinoma are provided. Included in the invention is an array of miRNA probes specific for identifying, diagnosing and prognosticating esophageal and gastrointestinal tract cancers and pre-cancerous lesions in subjects from blood or serum samples. A biochip comprising the array as well as methods for its use are also provided. | 2014-01-30 |
| 20140031259 | BIOMARKERS FOR PREDICTING SENSITIVITY TO CANCER TREATMENTS - Methods for predicting sensitivity to cancer treatments by assessing biomarkers and combinations of biomarkers include evaluating the presence of mutations to Akt, wherein the presence of said mutations correlates with the sensitivity of Akt inhibitors. | 2014-01-30 |
| 20140031260 | Molecular Diagnostic Test for Cancer - Methods and compositions are provided for the identification of a molecular diagnostic test for cancer. The test defines a novel DNA damage repair deficient molecular subtype and enables classification of a patient within this subtype. The present invention can be used to determine whether patients with cancer are clinically responsive or non-responsive to a therapeutic regimen prior to administration of any chemotherapy. This test may be used in different cancer types and with different drugs that directly or indirectly affect DNA damage or repair, such as many of the standard cytotoxic chemotherapeutic drugs currently in use. In particular, the present invention is directed to the use of certain combinations of predictive markers, wherein the expression of the predictive markers correlates with responsiveness or non-responsiveness to a therapeutic regimen. | 2014-01-30 |
| 20140031261 | OLIGONUCLEOTIDE REPLACEMENT FOR DI-TAGGED AND DIRECTIONAL LIBRARIES - Transposomes and oligonucleotide replacement methods to make DNA libraries that have distinct 5′ and 3′ tags, and to make directional libraries that are enriched for a desired strand. | 2014-01-30 |
| 20140031262 | Nanoliter Array Loading - An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid. | 2014-01-30 |
| 20140031263 | RESONANT MICROMACHINED BIOCHEMICAL SENSOR - A sensor system is formed from a micro machined resonant structure with multiple resonant elements, a tracking resonator control electronics, and signal processing algorithms. The moving elements of the resonator are coated with chemically active materials that change mass when exposed to the target chemical resulting in a change in frequency or period of oscillation. The changes in frequency or period are processed by multi-sensor chemical detection algorithms to identify chemical types and concentrations. In essence, the resonator and drive electronics form a closed loop oscillator operating at the resonator's natural frequency. The resonators are formed from silicon using photolithographic processes. The resonator design includes in-plane resonant motion combined with dynamic balance to operate with a high Q even in the presence of atmospheric pressure. | 2014-01-30 |
| 20140031264 | METHOD OF TREATING SUBTERRANEAN FORMATIONS - A method of treating a portion of a subterranean formation through the use of an aqueous fracturing fluid comprising dissolved therein from 0.3 to 3.0% by weight of a viscosifying agent, wherein the viscosifying agent consists of fast dissolving and easy dispersible glyoxalated, ground guar splits containing from 0.01 to 0.05% by weight of glyoxal. | 2014-01-30 |
| 20140031265 | CONTROLLED RELEASE OF SURFACTANTS FOR ENHANCED OIL RECOVERY - A sparingly soluble sulfonate-metal salt particle includes the metal ion salt of an alkyl aryl sulfonate, the metal ion salt of a petroleum sulfonate and a hydrophobically modified hydrophilic polymer, and has an average particle size diameter in a range of from about 50 nm to about 450 nm and is sparingly soluble in water at room temperature. A method of producing a sparingly soluble sulfonate-metal salt particle includes the steps of introducing an aqueous solution containing a metal ion salt into a reactor, introducing an aqueous solution containing a sulfonate surfactant and a polymer into the reactor, and operating the reactor such that the sparingly soluble sulfonate-metal salt particle forms from the interaction of the metal ion from the salt, the sulfonate surfactant and the polymer. | 2014-01-30 |
| 20140031266 | DELIVERY OF AGENTS TO THE CUTTING MECHANISM OF PAPER SHREDDERS - Lubrication system for application of lubricant to the cutting mechanism of paper shredders. Maintenance and lubrication can be performed by applying lubrication agents to the cutting mechanism of a paper shredder without requiring disassembly of the paper shredder. The agents can also include scented agents and decomposing agents or a combination thereof. Lubrication sheets are configured to apply agents to the cutting mechanism of paper shredders. A holder can be positioned on a housing of a paper shredder for retaining one or more lubrication sheets within proximity of the shredding mechanism of the paper shredder. Paper shredders may include means for identifying when lubrication is needed and/or when the cutting mechanism of the paper shredder has been lubricated by a lubrication sheet. | 2014-01-30 |
| 20140031267 | LUBRICANT ADDITIVE COMPOSITION - A lubricant additive composition includes oil soluble metal salts of inorganic and organic acids, and abrasive particles. Use of a lubricant additive composition includes oil soluble metal salts of inorganic and organic acids abrasive particles for wear protection of friction surfaces. | 2014-01-30 |
| 20140031268 | Continuously Variable Transmission Fluid with Extended Anti-Shudder Durability - A lubricant composition comprising (a) an oil of lubricating viscosity; (b) at least two nitrogen-containing materials, comprising (i) at least one amide of the formula R | 2014-01-30 |
| 20140031269 | Lubricant and Functional Fluid Compositions Containing Viscosity Index Improver - The disclosed invention relates to lubricant or functional fluid compositions containing viscosity index improvers in the form of self-healing polymers. The polymers may comprise one or more cleavable linkages, such as one or more disulfide bonds and/or one or more diene/dienophile linkages, to permit the polymer to reform if cleaved during use. | 2014-01-30 |
| 20140031270 | Fragrance Compounds - A method of providing a fragrant odour to an application, comprising the addition thereto of at least one compound of the formula I | 2014-01-30 |
| 20140031271 | Preparations for All-Purpose Cleaning Compositions - Multi-purpose cleaning compositions, in particular multi-purpose aqueous alkaline compositions for cleaning surfaces, and base preparations for this purpose. Such base preparations comprise one or more solvents that are at least partially water-miscible, one or more alkali metal salts of carboxylic acids, and water. Such multi-purpose cleaning compositions comprise at least such base preparation, a surfactant, a basifying agent, and water. | 2014-01-30 |
| 20140031272 | COMPOSITIONS - A composition comprising: (a) a lipolytic enzyme; (b) a hydrophobin, as defined herein; and optionally (c) a detergent; is provided. The composition is useful as a cleaning composition for removing lipid-based stains from surfaces. | 2014-01-30 |
| 20140031273 | BIODEGRADABLE STABILITY BINDING AGENT FOR A SOLID DETERGENT - A solid composition includes a polysaccharide hybrid polymer composition and a hydratable salt. In one embodiment, the polysaccharide hybrid polymer composition includes a polysaccharide residue present in an amount from approximately 5% to 90% by weight of the polysaccharide hybrid polymer composition and a residue of at least one ethylenically unsaturated monomer present in an amount from approximately 10% to 75% by weight of the polysaccharide hybrid polymer composition. | 2014-01-30 |
| 20140031274 | BIOLOGICAL ACTIVITY OF PLACENTAL PROTEIN 13 - The present invention relates to the biological and pharmacological effects of placental protein 13 (PP-13), an effect that may be used as a treatment and/or prevention of preeclampsia and placental insufficiencies, in pregnant female mammals, especially pregnant women. The invention relates to a method to treat female mammals with the purpose to precondition the uterine arteries and prevent and/or reverse the pathological conditions associated with placental insufficiency such as preeclampsia, HELLP and/or eclampsia. | 2014-01-30 |
| 20140031275 | METHODS OF ERADICATING BACTERIAL CELL POPULATIONS - Disclosed herein are methods and compositions for the eradication of bacterial infections. In particular, methods and compositions are disclosed for the eradication of persister and slow growing bacterial cell populations. In particular embodiments, the methods and compositions disclosed herein are useful for eradication of biofilms. | 2014-01-30 |
| 20140031276 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING A VIRAL INFECTION - A compound is provided which has a structure I: A-B-C and a method for administering the compound is also provided for use in the prophylaxis and/or treatment of a viral infection, and in particular for preventing and/or inhibiting viral replication, in which A is a quinoline or quinoline-like group, B is a sole amino acid or a peptide or polypeptide having a given amino acid sequence, and C is an O-phenoxy group. According to one embodiment, the compound is a protease inhibitor such as a caspase inhibitor, and the inhibitor can be Q-VD-OPh (N-(2-(quinolyl)valylaspartyl-(2,6-difluorophenoxy)methyl ketone), optionally in an O-methylated form. Antiviral compositions and kits are also provided. | 2014-01-30 |
| 20140031277 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE - The present invention relates to compounds of formula I: | 2014-01-30 |
| 20140031278 | Novel Glucagon Analogues - The present invention relates to novel glucagon peptides with improved stability and solubility at neutral pH, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The glucagon peptides of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity. | 2014-01-30 |
| 20140031279 | Human Insulin Analogues and Derivatives Comprising Cysteine Substitutions - The present invention relates to human insulin analogues containing a substituting cysteine, to human insulin derivatives containing a PEGylated substituting cysteine and methods of making such. The compounds of the invention may be useful for the treatment of diabetes. | 2014-01-30 |
| 20140031280 | METHODS FOR PREVENTING AND TREATING POST-TRAUMATIC STRESS DISORDER (PTSD) - Methods for preventing and/or treating symptoms of Post-Traumatic Stress Disorder (PTSD) are provided. The preferred method comprises administration of an effective amount of insulin to the upper one-third of a mammal's, preferably a human, nasal cavity, thereby enabling the administered at least one effective amount of insulin to bypass the patient's blood-brain barrier and be directly delivered to the patient's CNS. Another embodiment comprises utilizing vasoconstrictors to enhance targeting of an effective amount of insulin to the CNS while reducing non-target exposure. | 2014-01-30 |
| 20140031281 | POLYMER-BASED SUSTAINED RELEASE DEVICE - This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar. | 2014-01-30 |
| 20140031282 | FORMULATION FOR TREATMENT OF HYPERINSULINEMIC HYPOGLYCEMIA FOLLOWING GASTRIC BYPASS SURGERY - An effective combination of 6.25-100 mg of acarbose with a GLP-1 mimetic, such as 5-10 mg exenatide or 0.3-3.0 mg liraglutide. | 2014-01-30 |
| 20140031283 | ANTICANCER FUSION PROTEIN - A fusion protein comprising domain (a) which is the functional fragment of a hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and at least one domain (b) which is the sequence of an effector peptide having anti-proliferative activity against tumour cells, wherein the sequence of domain (b) is attached at the C-terminus or at the N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases. | 2014-01-30 |
