05th week of 2015 patent applcation highlights part 47 |
Patent application number | Title | Published |
20150031470 | GOLF CLUB - A golf club | 2015-01-29 |
20150031471 | Iron Golf Club Head - An iron golf club head has a strike plate mounted securely in a front face of a head body. The head body has a sealed cavity formed in back of the strike plate so that only the peripheral edge of the strike plate is connected to the head body. When the iron golf club head strikes the golf ball, the strike plate deforms to independently bear the striking force and the cavity provides room to receive the deformation of the strike plate. Therefore, the rebounding effect is enhanced when the iron golf club head hits the golf ball. | 2015-01-29 |
20150031472 | Golf Club Heads With Sole Weights And Related Methods - Some embodiments include a golf club head with a tapered sole weight. Other embodiments for related club heads and methods are also disclosed. | 2015-01-29 |
20150031473 | Sole with a Shaft Adjusting Hole for a Gold Club Head - A sole with a shaft adjusting hole for a golf club head includes a recessed portion adjacent to a striking portion and a root of the gold club head. The recessed portion includes a shaft adjusting hole. The sole of the golf club head is a plate separate from the striking portion and a crown of the golf club head. The shaft adjusting hole includes a bottom wall and a peripheral wall extending upward from the bottom wall. The peripheral wall includes a plurality of inclined plane faces. | 2015-01-29 |
20150031474 | GOLF CLUBS AND GOLF CLUB HEADS - A head for a ball striking device includes a face having a striking surface and a rear side located behind the face, a rear member connected to the rear side of the face member and having a front surface confronting the rear side of the face member, and a resilient material separating the rear member from the face member, such that the resilient member engages the rear member and the face member and is configured to transfer momentum between the face member and the rear member. The face member has projections extending rearwardly from the rear side of the face member proximate the heel and toe sides of the head. The rear member has receivers in the front surface on the heel and toe sides of the head, where the projections are received in the corresponding receivers. | 2015-01-29 |
20150031475 | GOLF BALLS HAVING A CORE LAYER MADE FROM PLASTICIZED THERMOPLASTIC COMPOSITIONS - Multi-layered golf balls containing a dual-core structure are provided. The core structure includes an inner core (center) comprising a thermoplastic composition, preferably including: a) ethylene acid copolymer, b) plasticizer, and c) cation source. Preferably, a fatty acid ester such as ethyl oleate is used as the plasticizer. The outer core layer is preferably formed from a thermoset composition such as polybutadiene rubber. The core layers have different hardness levels. The core assembly preferably has a positive hardness gradient extending across the entire assembly. The core structure and resulting ball have relatively good resiliency at given compressions. | 2015-01-29 |
20150031476 | GOLF BALL WITH DIMPLE PATTERN ARRANGED IN SPHERICAL POLYGONS HAVING SIDES WITH DIFFERENT LENGTHS - Provided is a spherical polyhedron division structure of a golf ball where dimples are arranged to have a well-defined symmetry and a dimple pattern. In the spherical polyhedron division structure, wherein an arbitrary point on a surface of a spherical body constituting a golf ball is defined as a pole, a great circle dividing the spherical body into a northern hemisphere and a southern hemisphere with respect to the pole as a reference point is defined as an equator, the surface of the spherical body is divided into six areas formed by segments connecting the pole and points obtained by dividing the equator in units of 60°, each area is divided into spherical polygons formed by four spherical rectangles and two spherical triangles having sides with different lengths, and the spherical polygons arranged in different adjacent areas are symmetric with each other. | 2015-01-29 |
20150031477 | GOLF BALL - A golf ball has a large number of dimples on a surface thereof. The golf ball meets the following mathematical formula (I): | 2015-01-29 |
20150031478 | Soccer Training Device - An inside foot soccer pass training device is disclosed. The passing device includes a curved race and a foot carriage that can travel from one end of the race to the other. The curved race guides the foot carriage into a proper technical position, which allows a user to improve their technique of the inside foot soccer pass. Embodiments include multiple tracks, an overall tensioner designed to strengthen inner leg muscles, an impact device designed to mimic the feel of hitting an actual soccer ball, and electric force monitors to compute both the impact the foot carriage makes on the impact device and the force on the foot carriage as it moves along the race. | 2015-01-29 |
20150031479 | Leg Drive Measuring and Training Apparatus for Baseball and Softball Pitchers - An apparatus for measuring a baseball and softball pitcher's “leg drive” for training and coaching purposes and for developing a strong leg drive. The apparatus includes a lower ground engaging plate and an upper pitcher's foot supporting plate. The plates are slidingly secured to one another such that the upper plate is linearly moveable relative to the lower plate. A force measuring element is provided between the upper and lower plates. A pitchers rubber is secured to the upper plate. A pitcher uses the apparatus by stepping on the upper plate and pushing against the rubber while pitching, thereby linearly moving the upper plate against the element. The element thereby provides an output indicative of the pitcher's leg drive. The element can be a load cell or a spring mechanism. An audible sound is generated when the spring force is overcome. | 2015-01-29 |
20150031480 | Ball Hurling Target Game and Associated Apparatus. - A game for at least 2 players wherein one of the players attempts to score points by hurling a plastic ball with the aid of a scoop racket into one of three scoring areas of their opponents “goal”. Opposing players stand at opposite ends of a playing field with said goal(s) positioned in front of each player. Goals are situated a certain distance apart from each other, the three scoring areas are mounted at adjustable heights above the playing surface and can be positioned in a common plane (or not). Said scoring areas are of various diameters and point values. Said scoring areas are distinctly apart from each other (not abutted) and are attached to a fixed post (standard). Points are awarded to players for hurling the ball into one of their opponent's scoring areas with point values inversely proportional to the diameter of the scoring area scored upon. | 2015-01-29 |
20150031481 | GAME BALL - The present disclosure relates to a game ball and methods for stitching a thread with a high coefficient of friction upon a stripe member present on the game ball. At least one stitching is thus formed upon the stripe member. The stitching formed from the thread enhances the grip and/or spin characteristics of the resulting game ball, improving handling and playability. | 2015-01-29 |
20150031482 | GAME BALL WITH GRIP ZONES - The present disclosure relates to a game ball having one or more grip zones that have greater frictional interaction compared to the outer surface of the game ball. The grip zones are made by stitching of a coated thread upon at least one cover panel to create the grip zone. The grip zone formed from the coated thread enhances the handling characteristics and playability of the resulting game ball. | 2015-01-29 |
20150031483 | BICYCLE DERAILLEUR - A bicycle derailleur is basically provided with a main body, a chain cage, a first pulley, a second pulley and a chain contact member. The main body is configured to be mounted to a bicycle. The chain cage is pivotally coupled to the main body movement between at least a first orientation and a second orientation. The first pulley is rotatably coupled to one of the chain cage and the main body. The second pulley is rotatably mounted to the chain cage to move therewith relative to the main body. The chain contact member is coupled to the main body. The chain contact member includes a non-rotatable chain contact portion that projects into a chain path between the first and second pulleys while the chain cage is in the first orientation, and that is located outside of the chain path between the first and second pulleys while the chain cage is in the second orientation. | 2015-01-29 |
20150031484 | TENSIONER WITH SINGLE TORSION SPRING HAVING MULTIPLE NESTED WINDINGS - A tensioner is disclosed that may be part of a power system where the tensioner provides tension to an endless power transmitting element such as a belt, chain, or other continuous loop. The tensioner includes an arm that is rotatable about a first axis and a spring. The spring has at least one inner winding, an outer winding, and a transition zone. The outer winding has an outer coil that defines an outer diameter. The inner winding has an inner coil that defines an inner diameter. The inner diameter of the inner coil is less than the outer diameter of the outer coil such that at least a portion of the inner winding is received by the outer winding. The outer winding and the inner winding of the spring both urge the arm to rotate about the first axis and into tensioning engagement with the power transmitting element. | 2015-01-29 |
20150031485 | TENSIONER WITH MULTIPLE NESTED TORSION SPRINGS - A tensioner is disclosed that may be part of a power system where the tensioner provides tension to an endless power transmitting element such as a belt, chain, or other continuous loop. The tensioner has an arm that is rotatable about a first axis. The tensioner also includes an outer spring and at least one inner spring. The outer spring has an outer coil that defines an outer diameter. The inner spring has an inner coil that defines an inner diameter. The inner diameter of the inner coil is less than the outer diameter of the outer coil such that at least a portion of the inner spring is received by the outer spring. The outer spring and the inner spring both urge the arm to rotate about the first axis and into tensioning engagement with the power transmitting element. | 2015-01-29 |
20150031486 | METHOD AND DEVICE FOR MANUFACTURING ENDLESS METAL RING, AND ENDLESS METAL RING - A method for manufacturing an endless metal ring by cutting an annular member made of maraging steel containing molybdenum into a ring element having a predetermined width, wherein a melted-solidified layer is formed on an outer circumference of the annular member, and the melted-solidified layers are arranged to be continuous in a circumferential direction of the ring element. | 2015-01-29 |
20150031487 | VEHICLE DRIVE DEVICE - A vehicle drive device having a control device making another first planetary gear device constituent member and a second planetary gear device constituent member non-rotatable by a brake to perform electric motor running for running with power of a second electric motor while an engine is put into a non-drive state, when the engine is started during the electric motor running the control device causing a first electric motor to rotate the engine while the other first planetary gear device constituent member and the one second planetary gear device constituent member are kept non-rotatable by the brake, and when the brake is released after start of the engine, the control device controlling the first electric motor before release of the brake so a torque applied to the brake due to power of the engine reaches a magnitude balancing with a torque applied to the brake due to a running load. | 2015-01-29 |
20150031488 | VEHICLE DRIVE DEVICE - A vehicle drive device comprising: an engine, a first electric motor, and a second electric motor disposed on a first axis; a first axis output portion outputting power of the first axis; a second axis input portion that is an input portion of a second axis to which power from the first axis output portion is input, the second axis being parallel to the first axis; a second axis output portion outputting power of the second axis; a transmission changing speed between the second axis input portion and the second axis output portion, the transmission being disposed on the second axis; and a third axis input portion that is an input portion of a third axis to which power from the second axis output portion is input, the third axis being parallel to the first axis, the first axis output portion, the second axis input portion, the second axis output portion, and the third axis input portion all being disposed between the first electric motor and the second electric motor in a direction of the first axis, the transmission including at least a first planetary gear device and a second planetary gear device, the second axis input portion and the second axis output portion being disposed between the first planetary gear device and the second planetary gear device in a direction of the second axis. | 2015-01-29 |
20150031490 | DIFFERENTIAL HAVING STEEL HYDRAULIC TRANSFER BUSHING - A differential gear mechanism constructed in accordance to one example of the present disclosure can include a differential casing defining first and second output shaft openings. The differential casing can have a case housing portion that defines fluid porting therein. The case housing portion including a hub extending therefrom. The hub can have an inner hub portion and an outer hub portion. The outer hub portion can be stepped down from the inner hub portion. The hub can include a stepped annular face at a transition between the inner and the outer hub portions. A hydraulic transfer bushing can be received by the outer hub of the case housing portion. The hydraulic transfer bushing can define fluid porting therein. The hydraulic transfer bushing can be disposed on the outer hub at a location where the fluid communication porting is fluidly connected to the fluid porting of the case housing portion. | 2015-01-29 |
20150031491 | POWER SHIFT TRANSMISSION - The invention relates to a power shift transmission ( | 2015-01-29 |
20150031492 | MULTI-SPEED TRANSMISSION - Transmissions with at least three gearing-arrangements with similar first and second gearing-arrangements that produce a number of transmissions having an eleven forward-speed and two reverse-speed ratios, having ten forward-speed and three reverse-speed ratios, and having five forward-speed and one reverse-speed ratios by selective engagement of three shift-elements in various combinations. Some embodiments include four simple planetary-gearsets and six shift-elements of which two or three are brakes. Another embodiment includes a double-pinion planetary-gearset and six shift-elements of which three are brakes. Other embodiments include three simple planetary-gearsets and five shift-elements of which one or two are brakes. | 2015-01-29 |
20150031493 | MULTI-RATIO TRANSMISSION - A multi-stage transmission having eight forward and one reverse gear includes planetary gearsets, shafts and shift elements. The sun gear of gearset (P | 2015-01-29 |
20150031494 | AUTOMATIC TRANSMISSION DEVICE - An automatic transmission is provided to adjust the speed between input and output members. The transmission is configured with four planetary gears having, (i) first to third rotary elements, (ii) fourth to sixth, (iii) seventh to ninth, and (iv) tenth to twelfth rotary elements. Three couplings are provided between (i) first and sixth rotary elements, (ii) second and ninth rotary elements, and (iii) third and eighth rotary elements. Three clutches are provided between (i) second coupling element and tenth rotary element, (ii) fifth and twelfth rotary elements, and (iii) fourth and tenth rotary elements. Three brakes are provided at (i) the fifth rotary element, (ii) the fourth rotary element, and (iii) seventh rotary element. The input member is connected to the tenth rotary element and the output member is connected to the third coupling element. | 2015-01-29 |
20150031495 | MULTI-RATIO TRANSMISSION - A multi-ratio transmission with nine forward and one reverse gear. Sun gears of first and third gearsets (P | 2015-01-29 |
20150031496 | MULTI-SPEED TRANSMISSION - A family of transmission gearing arrangements each establish at least one reverse gear ratio and between nine and fifteen forward gear ratios. A shiftable gearing arrangement establishes a variety of gear ratios speed ratio between the input and a first shaft. In some embodiments, a fixed speed ratio is established upstream or downstream of the shiftable gearing arrangement. In reverse and low gear ratios, a low clutch couples the first shaft to the output. In the high gear ratios, a combining planetary gear set establishes a linear speed relationship between the first shaft, a second shaft rotating at a speed proportional to the input, and the output. | 2015-01-29 |
20150031497 | MULTI-RATIO TRANSMISSION - A multi-stage transmission with eight forward and one reverse gear, including input and output shafts, planetary gearsets, gear stages, shift elements and shafts. Input shaft couples the carrier of gearset (P1) and, via clutch (15), can couple shaft (5) that couples the ring and sun gears respectively of gearsets (P2, P3). The ring gear of gearset (P1) couples shaft (6), which couples the sun gear of gearset (P2). Shaft (3) couples the sun gear of gearset (P1), can couple the housing via brake (03), and can couple shaft (8), which couples the ring gear of gearset (P3). The carrier of gearset (P2) couples shaft (4), which can couple the output shaft (2) via gear stage (S1) and clutch (24). The carrier of gearset (P3) couples shaft (7), which couples gear stage (S2), which couples the output shaft. A clutch (46, 56 or 45) can engage to block gearset (P2). | 2015-01-29 |
20150031498 | MULTI-RATIO TRANSMISSION - A multistage transmission with eight forward and one reverse gear, including an input and output shafts, planetary gearsets, gear stages, shift elements and shafts. The input shaft couples the carrier of gearset (P | 2015-01-29 |
20150031499 | DRIVE HUB FOR PLANET PINION CARRIER FREENESS CHECK - An assembly includes a sun gear that includes a external gear teeth and internal axial spline teeth, a drive hub including a first sleeve portion formed with lateral holes, and insert assemblies, each insert assembly including a sleeve located in one of the holes and secured to the first sleeve portion, a plunger located in the sleeve for displacement along the sleeve, and a spring urging the plunger laterally outward toward engagement with the spline teeth. | 2015-01-29 |
20150031500 | CONTINUOUSLY VARIABLE TRANSMISSION - Disclosed is a continuously variable transmission including: a pair of pressing means that form a torque transmission contact portion in a disk overlapping area where the input disk and the output disk are overlapped; target slip rate setting means that is configured to set a target slip rate between the input disk and the output disk in the torque transmission contact portion to a value higher than a torque transmission start slip rate in the torque transmission contact portion; and control means that is configured to control a force for clamping and pressing both the disks using the pressing means such that an actual slip rate in the torque transmission contact portion becomes the target slip rate. | 2015-01-29 |
20150031501 | HYBRID-ELECTRIC VEHICLE WITH CONTINUOUSLY VARIABLE TRANSMISSION - A hybrid-electric vehicle having a continuously variable transmission is provided. The continuously variable transmission further includes a forward disconnect clutch configured to selectively couple and decouple the continuously variable transmission and a first set of drive wheels. The hybrid-electric vehicle further includes a rear e-axle assembly, which allows the vehicle to operate in an electric-only mode, in which the vehicle is propelled with power generated solely by at least one electric power component. When the vehicle is operated in electric-only mode, the transmission disconnect clutch is disengaged, such that the continuously variable transmission is decoupled from the first set of drive wheels to allow the continuously variable transmission to operate in a low loss state. A method of transitioning an all-wheel drive hybrid-electric vehicle between an electric only mode and a hybrid mode, i.e., completing a “flying start,” is also provided. | 2015-01-29 |
20150031502 | METHOD FOR OPERATING A DRIVE TRAIN AND CONTROL DEVICE - A method for operating a drive train of a hybrid vehicle with a hybrid drive comprising at least an electric machine and an internal combustion engine, wherein an automated manual transmission is connected between the internal combustion engine and an output, wherein the electric machine is coupled via a friction clutch to a shaft of the automated manual transmission. Wherein in the automated manual transmission, by interruption of the drive torque provided by the hybrid drive on the output, shifts are executed in such a way that in a first phase the drive torque provided at the output is first reduced, subsequently in a second phase the actual gear shift is executed and following that in a third phase drive torque is built up at the output. Wherein for execution of the actual shift after a gear disengagement of an actual gear of the shift and before a gear engagement of a target gear of the shift, the automated manual transmission is synchronized using a flywheel mass of the electric machine such that, when the friction clutch is opened, the rotational speed of the electric machine is brought to an inertial rotational speed and that subsequently the friction clutch is first closed to the inertial synchronization of the manual transmission and subsequently at least partially opened again. | 2015-01-29 |
20150031503 | HYBRID SYSTEM CONTROL DEVICE - A control device of a hybrid system includes an engine; a motor/generator; an automatic clutch to a first engaging unit side of which an engine rotary shaft is connected; a differential device provided with a plurality of rotational elements to each of which an MG rotary shaft and a second engaging unit side of the automatic clutch are separately connected; a first transmission a rotary shaft of which is connected to the rotational element to which the second engaging unit is connected; a second transmission a rotary shaft of which is connected to another rotational element; and an output shaft connected to a driving wheel side, wherein at the time of EV driving, transmission control is performed and the automatic clutch is disengaged such that the first transmission and the second transmission can perform torque transmission between the input shaft and the output shaft. | 2015-01-29 |
20150031504 | VEHICLE ROLLBACK CONTROL APPARATUS AND METHOD - In one aspect of the invention there is provided a control system for a vehicle, the vehicle having a powertrain comprising a prime mover and a driveline, the control system being configured selectively to control the driveline to assume a first state in which a transmission of the driveline is substantially fully connected to the prime mover and a second state in which when the vehicle is stationary the transmission is at least partially disconnected or decoupled from the prime mover thereby to reduce a torque loading on the prime mover, the control system being configured to control the driveline to assume the second state when the vehicle is held stationary by brake means in response to actuation of driver operable brake control means, the control system being operable upon release of the brake control means to verify that a first portion of a powertrain of the vehicle is rotating at a speed exceeding a prescribed threshold and to command the driveline to assume the first state before permitting release of the brake means. | 2015-01-29 |
20150031505 | HYBRID ELECTRIC WEIGHT DEVICE - A hybrid electric weight device applying to exercise equipment, comprising: a frame body, a load mechanism having a main shaft, a motor torque member and a spring member, a force mechanism having at least a set of rods, load cells and handles, an acceleration processing board having an acceleration sensor and a microprocessor, a digital watch arranged on the frame body for users inputting an exercise set value; and a servo controller. When operating the force mechanism, the users feel the load generated by both motor torque member and spring member of the load mechanism; the servo controller continues to compare differences in the value of the load cell, digital watch and acceleration processing board and then corrects the current value to drive the motor torque member for the users feeling smooth while operating the force mechanism. | 2015-01-29 |
20150031506 | RESPIRATORY MUSCLE ENDURANCE TRAINING DEVICE AND METHOD FOR THE USE THEREOF - A respiratory muscle endurance training device (RMET) includes a chamber and a patient interface. In one implementation, one or both of a CO, sensor or a temperature sensor can be coupled to the chamber or patient interface to provide the user or caregiver with indicia about the CO, level in, or the temperature of, the chamber or patient interface, and/or the duration of use of the device. In another implementation, the RMET may have a fixed volume portion adjustable to contain a measured portion of a specific patient's inspiratory volume capacity. Methods of using the device are also provided. | 2015-01-29 |
20150031507 | Device Suitable For Rehabilitation And Use Thereof - A system for extending a finger of a hand comprises structural elements configured to be inserted into a flexed finger and capable of providing a controllable force to extend the finger. In some embodiments, structural elements comprise a cam connected to a spacer, the spacer connected to a first strut, and a second strut holding a loading assembly, an end piece and a spring. The loading assembly compresses or relaxes the spring, which exerts a variable force on the end piece, which rotates the cam and the first strut about an extension angle. When the extension angle is minimal, the first and second struts are substantially parallel. A method of extending a finger of a hand substantially fixed in a flexed position comprises inserting a system comprising structural elements into the finger and thereafter providing a force to extend the finger and maintaining the force for a period of time. | 2015-01-29 |
20150031508 | MULTIFACETED LINEAR TRAINING DEVICE - The present invention, the Multifaceted Linear Training Device, is a pliable exercise device that allows the user to perform various resistance exercises. This exercise invention consists of a resilient pliable outer shell, a supple padded inner sheath, and a flexible weighted inner mass with a multitude of fastening straps and handles designed to enhance the strength training effectiveness of this device. These handles provide an ergonomic user interface for this resistance system and thus a unique method to exercise the entire body. When the straps and handles are combined, this innovative device may be transformed into a weight vest and worn during exercise. This multifaceted resistance system allows the user a choice of dead, dynamic, or progressive weight training options. This invention may also be integrated with free-weights and other traditional workout equipment to create new enhanced training exercises. | 2015-01-29 |
20150031509 | Weight Training Barbell System - A weight training barbell system provides modifiable barbells that facilitate the attachment of plate weights, various elastic straps, inelastic bands, handles, grips, and connectors, in a compact space saving design. The weight training barbell system incorporates various features that allow it to perform specialized exercises that provide same or greater intensity from a workout using lower weights. The weight training barbell system accomplishes this through the use of specialized components that permit a user to redistribute weight along the length of the bar and components that add resistance, in more than one direction, while lifting the bar. The weight training barbell system can be utilized to perform compression lifting exercises, offset lifting exercises, and self spotting exercises. | 2015-01-29 |
20150031510 | GYROSCOPIC APPARATUSES AND METHODS OF USING SAME - A gyroscopic exercise apparatus, comprising: at least one control-moment gyroscope; at least one motion sensor for sensing movement of the apparatus; at least one spindle motor for providing rotation to a rotor of the gyroscope; and, at least one reversible motor for providing rotation to at least one gimbal of the gyroscope. | 2015-01-29 |
20150031511 | SYSTEM FOR RESISTANCE TRAINING - A portable athletic training system which permits a user to perform resistance exercises while stationary or in motion comprising a form fitting torso wrap, at least one wrist wrap, at least one ankle wrap, and at least one elastic cord removably connected between to a loop to perform resistance exercises. The anterior of the torso wrap incorporates a loop in each quadrant, each lateral portion incorporates a loop, and the posterior portion incorporates at least three loops positioned vertically aligned with the user's spine with one loop proximal to the user's cervical spine, one loop proximal to the user's thoracic spine, and one loop proximal to the user's lumbar spine. | 2015-01-29 |
20150031512 | DOOR-MOUNTED PORTABLE EXERCISE APPARATUS - A door-mounted portable exercise apparatus having a non-elastic adjustable strap that extends vertically around a door. An attached connector maintains the adjustable strap in a snug position around the door. A first anchor and a second anchor are secured to the adjustable strap by a re-enforcing strap near the top edge of the door. When the door is closed, the first anchor is positioned near the junction of the closing face of the door and the door frame, and the second anchor is positioned near the junction of the opening face of the door and the door frame. At least two non-elastic loops are attached near the top and bottom of the adjustable strap by short strips on the closing side of the door. Elastic bands of various tensions can be attached to or passed through at least one non-elastic loop of the apparatus to permit a wide range of exercise motions by a user. | 2015-01-29 |
20150031513 | AUXILIARY DEVICE FOR EXERCISING ABDOMINAL MUSCLES - There is provided an auxiliary device for abdominal muscle exercise, and more particularly, to an auxiliary device for abdominal muscle exercise having a simple shape in which two supports are connected to each other by a board for easily exercising and strengthening the body. To achieve the objects of the present invention, the auxiliary device for abdominal muscle exercise comprises: a first support ( | 2015-01-29 |
20150031514 | MULTIPURPOSE EXERCISE APPARATUS - An exercise apparatus for cooperating with an exercise ball during performance of core exercises thereon. The exercise apparatus comprises: (i) an exercise platform comprising a framework defining a first opening approximate its proximal end for receiving therein a first padded exercise mat and a second opening approximate its distal end for receiving therein a second padded exercise mat; (ii) an upright framework engaged with the exercise platform framework at its proximal end, the upright framework having a vertically adjustable backplate with an adjustable headrest and an adjustable handlebar grip, a handgrip support rail and a stabilizer bar integrally engaged with the proximal end of the exercise platform; (iii) a first padded exercise mat for demountable installation into the first opening defined in the exercise platform framework; and (iv) a second padded exercise mat for demountable installation into the first opening defined in the exercise platform framework. | 2015-01-29 |
20150031515 | Cast Device with Implanted Tubes - A cast device useable with an image forming apparatus is provided. The cast device includes at least one tube and a cast body. The cast body includes the at least one tube implanted into the cast body using a combined casting process. | 2015-01-29 |
20150031516 | Lid For Beverage Container - A lid for a beverage container is described. The lid has a basin that is designed to enhance the user's olfactory experience when drinking a beverage from the container and lid. As the user tilts the container and lid to take a drink, the beverage pours through an opening on the basin valley and flows across a sipping surface area to the user's mouth, thus allowing the beverage to aerate, evaporate, and cool. The basin is sized and dimensioned to channel and concentrate the vapor rising from the beverage towards the user's nose as the user sips the beverage. The basin and the opening are sized and dimensioned to provide a comfortable and secure feeling when drinking hot beverages. In this manner, the lid enhances the drinker's olfactory experience and provides better controllability of the flow of a hot beverage to prevent burn injuries. | 2015-01-29 |
20150031517 | PACKING METHOD AND UNIT FOR FOLDING A BLANK ON A PACKING MACHINE - A packing method and unit for folding a blank on a packing machine; a first suction pickup head engages a first panel of the blank inside a store; a second suction pickup head engages a second panel of the blank inside the store; the pickup heads are moved from a withdrawal position at the store to a release position at a packing conveyor, insert the blank inside a pocket on the packing conveyor; and the blank, folded into a ‘U’, is released inside the pocket on the packing conveyor; as the pickup heads are moved from the withdrawal position to the release position, a relative movement between the first pickup head and the second pickup head is produced to fold the blank into a ‘U’ before the blank is inserted into the pocket on the packing conveyor. | 2015-01-29 |
20150031518 | PEELABLE SEALS INCLUDING POROUS INSERTS - Peelable seals including porous inserts are described. An example peelable seal includes a porous insert positioned between a first sheet and a second sheet. The porous insert includes a plurality of interwoven strands and a plurality of pores adjacent the interwoven strands through which a bond is formed between the first sheet and the second sheet when heat is applied to at least one of the first sheet, the second sheet or the porous insert. | 2015-01-29 |
20150031519 | PACKING UNIT AND METHOD FOR FOLDING A BLANK ON A PACKING MACHINE - A packing unit and method for folding a blank on a packing machine; the packing unit having: a packing conveyor having at least one pocket for receiving the blank; and a feed device for inserting the blank into the pocket on the packing conveyor; the packing conveyor has at least a first conveyor belt defining a bottom wall, of the pocket; at least a second conveyor belt separate from, parallel to, and alongside the first conveyor belt, and defining the bottom wall of the pocket together with the first conveyor belt; a first retaining member, which projects perpendicularly from the first conveyor belt and defines a front wall of the pocket; and a second retaining member, which projects perpendicularly from the second. conveyor belt and defines a rear wall of the pocket. | 2015-01-29 |
20150031520 | SHEET PROCESSING APPARATUS AND IMAGE FORMING SYSTEM - A sheet processing apparatus including a first conveying member that conveys a sheet, a second conveying member that receives the sheet conveyed by the first conveying member and further conveys the sheet to a subsequent stage, a third conveying member that receives the sheet conveyed by the first conveying member and further folds the sheet, a guiding member that guides the sheet when the sheet is folded by the third conveying member, and is arranged between the second conveying member and the third conveying member. The sheet is guided along the guiding member when a bending part of the sheet is conveyed to the third conveying member by rotating the second conveying member in a reverse direction while the sheet is held by the first conveying member and the second conveying member. | 2015-01-29 |
20150031521 | SAMPLE CARRIER CENTRIFUGE - The invention relates to a sample carrier centrifuge for a sample carrier ( | 2015-01-29 |
20150031522 | CARBON-CARBON COMPOSITES INCLUDING ISOTROPIC CARBON ENCAPSULATING LAYER AND METHODS OF FORMING THE SAME - A technique of forming a carbon-carbon composite material includes infusing a liquid carbonizable precursor into a porous preform, and the infused precursor is subsequently pyrolyzed to convert the precursor to isotropic carbon. The preform then can be densified with a densifying agent, followed by infusion of the liquid carbonizable precursor into the densified preform. In some examples, after pyrolyzing the liquid carbonizable precursor, isotropic carbon extends substantially throughout a volume of the carbon-carbon composite material. | 2015-01-29 |
20150031523 | Scheelite Microwave Dielectric Ceramic Material and Preparation Method Thereof - An embodiment of the present invention provides a scheelite microwave dielectric ceramic material. For example, a structure expression of the scheelite microwave dielectric ceramic material can be Bi(V | 2015-01-29 |
20150031524 | CRYSTALLIZABLE GLASS COMPOSITION - A crystallizable glass composition containing, in % by mole in glass component composition, 40 to 70% SiO | 2015-01-29 |
20150031525 | OPTICAL GLASS AND USE THEREOF - An optical glass is oxide glass wherein Si | 2015-01-29 |
20150031526 | TUNGSTEN/TITANIA OXIDATION CATALYST - A catalyst article for treating an emission gas is provided comprising (a) an oxidation catalyst comprising at least one noble metal on a WO | 2015-01-29 |
20150031527 | Polyisocyanate Trimerization Catalyst Composition - A trimerization catalyst composition comprising a trimerization catalyst compound selected from one or more organic metal salt, preferably alkali or earth alkali metal salts, and one or more compounds selected from compounds which comprise a carboxamide group having the structure —CO—NH | 2015-01-29 |
20150031528 | PROCESS FOR PRODUCING CARBON SUBSTRATES LOADED WITH METAL OXIDES AND CARBON SUBSTRATES PRODUCED IN THIS WAY - The present invention relates to a process for producing a carbon substrate loaded with metal oxides, in particular a carbon material which contains metal oxide nanoparticles and is preferably suitable for use in a catalyst and/or as a catalyst, wherein, in a first process step, nanoparticles of metal oxides are introduced into a matrix based on at least one organic polymer, in particular are dispersed therein, and, in a second process step, the polymer matrix containing the nanoparticles is subsequently carbonised to carbon, optionally followed by a third process step of activation. | 2015-01-29 |
20150031529 | CATALYST UNIT - A catalyst unit may include a first brick having a first noble metal layer formed along an exhaust gas passage thereof and being disposed on a space that an exhaust gas flow rate may be a predetermined rate, a second brick being disposed onto the first brick and having a second noble metal layer formed along an exhaust gas passage thereof, wherein the second brick may be disposed on a space that an exhaust gas flow rate may be lower than the predetermined rate, and wherein the first brick and the second brick may be attached together to fix the second brick onto the first brick. | 2015-01-29 |
20150031530 | ENGINE EXHAUST CATALYSTS CONTAINING COPPER-CERIA - An emission control catalyst includes copper-ceria to boost low temperature CO oxidation performance, generate exothermic heat during the process, and reduce HC and NO | 2015-01-29 |
20150031531 | Self-Ignition Resistant Thermally-Activated Carbon - Thermally-activated cellulosic-based carbon is rendered more thermally stable by exposure to a halogen and/or a halogen-containing compound. Such treated cellulosic-based carbon is suitable for use in mitigating the content of hazardous substances in flue gases, especially flue gases having a temperature within the range of from about 100° C. to about 420° C. | 2015-01-29 |
20150031532 | Production Of Stabilized Channel Type Cyclodextrin Crystals - The present invention relates to stabilized channel type cyclodextrin crystals. In particular the present invention relates to a method for producing stabilized channel type cyclodextrin crystals, stabilized channel type cyclodextrin crystal comprising a stabilizer, uses of said stabilized crystals and products comprising stabilized channel type cyclodextrin crystals. | 2015-01-29 |
20150031533 | PESTICIDAL MIXTURES INCLUDING SPIROHETEROCYCLIC PYRROLIDINE DIONES - A pesticidal mixture comprising as active ingredient a mixture of component A and component B, wherein component A is a compound of formula (I), in which Q is i or ii wherein X, Y and Z, m and n, A, G, and R, are as defined as in claim | 2015-01-29 |
20150031534 | PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES - Provided is a pesticidal | 2015-01-29 |
20150031535 | Liquid concentrate formulation containing a pyripyropene insecticide III - The present invention relates to a liquid concentrate formulation comprising a pyripyropene pesticide of the formula I as defined below and an alkoxylated aliphatic alcohol as an adjuvant. Moreover, the invention relates to the use of the formulations for the treatment of plants and seed and to corresponding methods. | 2015-01-29 |
20150031536 | HERBICIDAL SULFINIMIDOYL- AND SULFONIMIDOYL BENZOYL DERIVATIVES - The invention relates to sulfmimidoyl- and sulfonimidoylbenzoyl derivatives of the general formula (I). In said formula (I), R, R′, X, W and Z represent radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogens. Q represents a cyclohexandionyl-, pyrazolyl-oder isoxazolyl radical. | 2015-01-29 |
20150031537 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES - There are described 4-nitro-substituted N-(tetrazol-5-yl)-, N-(triazol-5-yl)- and N-(1,3,4-oxadiazol-2-yl)arylcarboxamides of the general formula (I) as herbicides. | 2015-01-29 |
20150031538 | HERBICIDAL PICOLINIC ACID SALT COMPOSITION - A herbicidal concentrate composition comprising a mixture of the monomethylamine and dimethylamine salts of at least one picolinic acid herbicide of formula (Ia): | 2015-01-29 |
20150031539 | Tank mix adjuvant comprising an alkyl polyglucoside and a base - The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base. The invention also relates to a use of a tank mix adjuvant for increasing the efficacy of a pesticide, wherein the tank mix adjuvant comprises an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base; to a tank mix adjuvant which comprises an auxiliary, an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base; to a tank mix adjuvant which comprises an auxiliary, an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, wherein the tank mix adjuvant is present in form in form of a particulate solid, which contains at least 10 wt % of the base; and to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment. | 2015-01-29 |
20150031540 | PYRIDAZINONE HERBICIDAL COMPOUNDS - The present invention relates to compounds of Formula (I), or an agronomically acceptable salt of said compounds wherein X | 2015-01-29 |
20150031541 | MICROBIOCIDAL PYRAZOLE DERIVATIVES - Compounds of the formula (I) wherein the substituents are as defined in claim | 2015-01-29 |
20150031542 | POLYURETHANE DISPERSIONS FOR SEALING THE TEATS OF THE MAMMARY GLANDS IN MILKING ANIMALS - The present invention relates to aqueous polyurethane dispersions for sealing teats of animal mammary glands. | 2015-01-29 |
20150031543 | COMPOSITIONS FOR AEROSOLIZATION OF HIGHLY CONDUCTIVE SOLUTIONS - Compositions for aerosolization of conductive solutions (preferably highly conductive solutions) by way of electrostatic or electrohydrodynamic spraying are provided. Methods for making and using these compositions and electrostatic and electrohydrodynamic aerosol generators containing these compositions are also provided. | 2015-01-29 |
20150031544 | DRY GLASSY COMPOSITION COMPRISING A BIOACTIVE MATERIAL - The present invention relates to formulations and methods for stabilizing and protecting of biologic materials during harsh storing and use conditions, wherein the formulations relate to embedded bioactive materials and biologics, including live bacteria, in a protective glassy matrix. | 2015-01-29 |
20150031545 | ARRANGEMENT WITH THREE SUPERCONDUCTIVE PHASE CONDUCTORS - An arrangement is provided with three superconductive phase conductors each with a conductor, a dielectric and an electrically conductive screen surrounding the dielectric. The three phase conductors are arranged in a cryostat which conducts a cooling agent and which is made from a pipe with a thermal insulation. The screens of each of the conductors are for forming three, or a whole number multiple of three, sections arranged successively in the longitudinal direction by partial screens in a first, a second and a third section at two locations or at two locations spaced apart from each other. The partial screen of a first section of each phase conductor is electrically conductively connected in series to the partial screens of the second section and further to the third section of the two other phase conductors. | 2015-01-29 |
20150031546 | CONNECTION STRUCTURE FOR SUPERCONDUCTING CABLES - A connection structure for superconducting cables includes: superconducting cables that are connected to each other and include cable cores containing formers and superconducting conductor layers, and each cable core is housed in a thermal insulation tube with a cooling medium, wherein the cable cores include electric insulating layers obtained by winding insulating sheets around the superconducting conductor layers, the electric insulating layers on both sides of a conductor connecting part, in which the formers and the superconducting conductor layers are connected to each other, include taper shape portions each having a diameter reducing towards the conductor connecting part, each taper shape portion is formed so as to have an inclination angle changing in a stepwise fashion by a plurality of tapered portions among which a tapered portion nearer the conductor connecting part has smaller inclination angle, and a reinforcing insulating layer is provided between the taper shape portions. | 2015-01-29 |
20150031547 | METHOD OF ELECTRICALLY CONDUCTIVELY CONNECTING TWO SUPERCONDUCTIVE CABLES - A method is disclosed for electrically conductively connecting two superconductive cables. The ends of the two cables are arranged next to each other and parallel to one another, in such a way that their free ends point in the opposite direction, and their conductors are located at least approximately on the same level next to each other. Two conductors of the two cables are electrically conductively connected to each other through electrical contact elements ( | 2015-01-29 |
20150031548 | Band-Shaped superconducting element with improved self-protection in case of quenching - A superconducting element ( | 2015-01-29 |
20150031549 | Cellular High Throughput Encapsulation for Screening or Selection - The invention relates to a method for selecting a sequence set from a library of expressed nucleic acid sequences, wherein cells are provided, each cell comprises an expressed nucleic acid sequence expressed as a target protein. The cells are encapsulated by treating them with a cationic polysaccharide and subsequently treating them with an anionic polysaccharide, yielding encapsulated cells, perforating the membrane of the encapsulated cells, yielding solubilized compartments, contacting them with a ligand to said target protein, the ligand bearing a detectable label, and selecting a subset of solubilized compartments as a function of detectable label and isolating the expressed nucleic acid sequences from the selection as a selected sequence set. | 2015-01-29 |
20150031550 | HUMAN ANTIBODIES AND PROTEINS - The present invention provides composite proteins, including antibodies, which show reduced immunogenicity. In particular, composite antibodies for use in humans are provided, in particular antibodies which have been modified to remove one or more T-cell epitopes. Methods for generating such proteins are also provided. | 2015-01-29 |
20150031551 | CONTROL NUCLEIC ACID SEQUENCES FOR USE IN SEQUENCING-BY-SYNTHESIS AND METHODS FOR DESIGNING THE SAME - A method for nucleic acid sequencing includes (a) disposing a plurality of template polynucleotide strands in a plurality of defined spaces disposed on a sensor array, at least some of the template polynucleotide strands comprising a test or control sequence; (b) exposing a plurality of the template polynucleotide strands in the defined spaces to a series of flows of nucleotide species flowed according to a predetermined ordering; and (c) determining sequence information for a plurality of the template polynucleotide strands in the defined spaces based on the flows of nucleotide species to generate a plurality of sequencing reads corresponding to the template polynucleotide strands, wherein the test or control sequence comprises a sequence determined by identifying, using a variant caller, loci with systematic errors present in a plurality of sequencing runs included in a training set of sequencing runs. | 2015-01-29 |
20150031552 | METHOD FOR DETECTING HYDROXYLMETHYLATION MODIFICATION IN NUCLEIC ACID AND USE THEREOF - A method for detecting hydroxymethylation modification in nucleic acid comprises: glycosylating the nucleic acid, digesting with MspI, ligating the digested fragments to a biotin-labeled linker at both ends thereof, digesting with NlaIII; capturing the digested fragments using streptavidin magnetic beads to produce fragments having the biotin-labeled linker at one end and a CATG 4-base sticky end at the other end, wherein these fragments reveal modification information of their adjacent CCGG sites; ligating the CATG sticky end to a linker containing a recognition site of MmeI or Ecop15I, digesting with corresponding restriction endonuclease to produce short sequence fragments that can reveal modification information of their adjacent CCGG sites; and performing a tag number comparison to obtain information about methylation and hydroxymethylation modification relative levels. A use of the method is also provided. | 2015-01-29 |
20150031553 | METHOD OF MEASURING IMMUNE ACTIVATION - The invention is directed to a method of detecting immune activation in an individual by measuring frequencies and sizes of certain groups of related clonotypes, referred to herein as “clans,” in a clonotype profile of the individual. A clan may arise from a single lymphocyte progenitor that gives rise to many related lymphocyte progeny, each possessing and/or expressing a slightly different immunoglobulin receptor due to somatic mutation(s), such as base substitutions, inversions, related rearrangements resulting in common V(D)J gene segment usage, or the like. Immune activation is correlated to frequencies and sizes of clans in a clonotype profile exceeding reference values for those features. | 2015-01-29 |
20150031554 | EXTRACELLULAR TELOMERE ASSAY - Provided herein is a method of detecting a level of cell injury in a subject, the method comprising detecting an amount of extracellular telomeres in a biological sample from the subject. The amount of extracellular telomeres as compared to a control amount indicates the level of cell injury in the subject. Further provided is a kit for detecting a level of apoptosis in a subject, the kit comprises first and second nucleic acid sequences, wherein the first and second nucleic acid sequences hybridize with an extracellular telomere; and a container. The first and second nucleic acid sequences can comprise SEQ ID NO: 1 and SEQ ID NO:2. | 2015-01-29 |
20150031555 | METHOD FOR CORRECTION OF BIAS IN MULTIPLEXED AMPLIFICATION - This invention relates a method to correct for bias inherent to multiplexed sequence amplification. The resulting corrected data is a much more accurate representation of true quantities than unprocessed data. | 2015-01-29 |
20150031556 | SYSTEM AND METHOD OF GENOMIC PROFILING - The present invention relates to a system and method of genomic profiling and is particularly useful in genomic differentiation of heterogeneous and polyclonal neoplastic cell populations, preferably of flow sorted formalin fixed paraffin embedded samples. The present invention includes methods of improving resolution for identifying aberration in variable carcinoma genomes and/or heterogeneous cell populations. The present invention also includes kits configured to improve genomic resolution and the ability to identify genomic aberration in variable and/or heterogeneous cell populations. | 2015-01-29 |
20150031557 | DETECTION OF SHIGA TOXIN GENES IN BACTERIA - The disclosed invention is related to methods, compositions and kits for targeting nucleic acid derived from Shiga toxin-producing bacteria such as | 2015-01-29 |
20150031558 | METHODS, COMPOSITIONS AND SYSTEMS FOR SAMPLE DEPOSITION - Methods, compositions, systems, apparatus, and kits are provided for depositing samples onto surfaces. The samples can include one or more particles, and the surface can include one or more reaction chambers. In some embodiments, the depositing can include the use of companion particles in combination with sample particles. | 2015-01-29 |
20150031559 | Increased Confidence of Allele Calls with Molecular Counting - Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications. | 2015-01-29 |
20150031560 | SEQUENCING BY ORTHOGONAL SYNTHESIS - A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates. | 2015-01-29 |
20150031561 | BIOMARKER PANELS, DIAGNOSTIC METHODS AND TEST KITS FOR OVARIAN CANCER - Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject potentially is developing cancer. Associated test kits, computer and analytical systems as well as software and diagnostic models are also provided. | 2015-01-29 |
20150031562 | BIOMARKERS FOR MULTIPLE SCLEROSIS AND METHODS OF USE THEREOF - Biomarkers useful for identifying treatments for and monitoring treatment of patients with multiple sclerosis (MS) are provided, as well as methods for their identification, methods of diagnosing MS, relapse of MS patients and disease progression in MS patients. | 2015-01-29 |
20150031563 | Multi Component Antibody Based Detection Technology - The disclosure provides methods for detecting the concurrent presence of at least two targets within a biological sample. The method includes contacting said biological sample with a first binding agent, said first binding agent operably linked to a first sortase molecule, wherein said first binding agent specifically binds to a first target; contacting said biological sample with a second binding agent, said second binding agent operably linked to a first sortase recognition sequence peptide, wherein said second binding agent specifically binds to a second target; adding a sortase substrate under conditions where a first sortase-mediated ligation of the sortase substrate to the first sortase recognition sequence will produce a ligation product, and detecting the ligation product, wherein detection of said ligation product indicates the concurrent presence of the first target and the second target in the biological sample. Also disclosed are kits comprising reagents for performing the methods as claimed. | 2015-01-29 |
20150031564 | LIGAND HAVING THREE FINGER STRUCTURE AND A METHOD FOR DETECTING A MOLECULE BY USING THEREOF - The present invention improves in vitro virus synthesis efficiency and stability of mRNA derived from screened cDNA in a cDNA display method to improve the efficiency and reliability of the production of a peptide by a molecular evolutionary engineering technique. Provided is a ligand which comprises three fingers formed from antiparallel β-sheets and a loop region intercalated between the antiparallel β-sheets, wherein at least a fingertip part formed by the loop region of each of the fingers is bound to the target molecule, and wherein the ligand comprises the amino acid sequence of SEQ ID NO: 1. In the amino acid sequence of SEQ ID NO: 1, X7 represents an arbitrary amino acid residue that constitutes the fingertip part of each of the fingers, each numeric character represents the number of amino acid residues, and X7 and X4 are not composed of the same amino acid residues as each other. | 2015-01-29 |
20150031565 | DETERMINATION OF THE IDENTITIES OF SINGLE NUCLEOTIDE POLYMORPHISMS, POINT MUTATIONS AND CHARACTERISTIC NUCLEOTIDES IN DNA - A method of genotyping single nucleotide polymorphisms (“SNP”) and point mutations in nucleic acid based on chain extension by polymerase. This invention is based on the fact that the neighboring sequence immediately 3′ adjacent to the site is known, and the nucleoside immediately 5′ adjacent to any SNP/point mutation site is also known. An extension primer complementary to the sequence directly adjacent to the SNP on the 3′ side of a target polynucleotide is used for chain extension. Up to four different polymerase reaction mixtures are provided in separate reaction containers, each containing one different potentially chain-extending Bridging Nucleotide. A Reporting Nucleotide having a base complementary to the nucleotide directly adjacent to the SNP on the 5′ side of the target polynucleotide may also be added to each reaction container. | 2015-01-29 |
20150031566 | BIOTINYLATED MHC COMPLEXES AND THEIR USES - The invention demonstrates an improved choice of biotinylation peptide to be used in a combination or fusion with an MHC molecule for immobilizing or multimerising such MHC molecules for a variety of purposes. | 2015-01-29 |
20150031567 | miRNA Biomarkers For Ulcerative Colitis - Methods for diagnosing inflammatory bowel disease and ulcerative colitis using miRNA biomarkers for these diseases are provided. Differential expression of the miRNA biomarkers in blood fractions, e.g., platelets, of diseased individuals as compared to expression levels in normal individuals indicates the presence of IBD or ulcerative colitis. Also provided are microarrays for use in the diagnostic methods, wherein the features of the microarray consist essentially of nucleic acid sequences that hybridize to the miRNA biomarkers and normalization controls. | 2015-01-29 |
20150031568 | METHOD FOR MEASURING PHYSIOLOGICALLY ACTIVE SUBSTANCE OF BIOLOGICAL ORIGIN, AND MICROPARTICLES AND EXTRACT FOR USE IN THE METHOD - Provided is a technique which can detect a physiologically active substance of biological origin or measure the concentration of the physiologically active substance of biological origin with higher accuracy or within a shorter period even when a sample that contains the physiologically active substance of biological origin at an extremely low concentration or a sample that contains a component capable of interfering with an AL is used. Microparticles capable of adsorbing a specific physiologically active substance, e.g., an endotoxin, is dispersed in a sample containing the specific physiologically active substance to cause the adsorption of the specific physiologically active substance onto the microparticles, thereby concentrating the specific physiologically active substance in the sample. Subsequently, the microparticles are separated and collected, then are reacted with an AL to cause an aggregation reaction, and the aggregation is detected by an optical means. In this manner, the measurement of the specific physiologically active substance can be carried out. | 2015-01-29 |
20150031569 | Mutations of the GPR179 Gene in Congenital Stationary Night Blindness - The present invention relates to an in vitro method for diagnosing a complete congenital stationary night blindness (cCSNB) in a subject, which method comprises determining the presence of an alteration in the GPR179 gene in a biological sample of said subject. Screening methods and therapeutic applications are further described. | 2015-01-29 |
20150031570 | METHOD AND APPARATUS FOR RAPID, HIGH SENSITIVITY ANALYSIS OF LOW VOLUME SAMPLES OF BIOLOGICAL MATERIALS - A high throughput biological sample processing system includes a sample carrier with a plurality of wells that progresses through the high throughput biological sample processing system. The system further includes a sample dispensing module, a reagent dispensing module, an accumulation/incubation module, and a detection module. The detection module employs an optical measuring device to encapsulate a biological sample in one of the plurality of wells of the sample carrier and detect energy from the chemistry of the biological sample to determine the amount of an analyte in the biological sample. | 2015-01-29 |