04th week of 2012 patent applcation highlights part 41 |
Patent application number | Title | Published |
20120021346 | IMAGE BEARING MEMBER AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING SAME - An image bearing member having a substrate and a layer provided overlying the substrate, which has a cured material in which a compound comprising three or more methylol groups and a charge transport group is cross-linked. | 2012-01-26 |
20120021347 | TONER, METHOD FOR FORMING TONER, DEVELOPER, AND IMAGE FORMING METHOD - To provide a toner A containing: base particles, each containing polyester, microcrystalline wax, and a colorant; and spherical silica particles having an average primary particle diameter of 100 nm to 150 nm, wherein the microcrystalline wax has an onset temperature of 45° C. to 60° C. as determined by DSC, and a carbon number distribution of 25 to 55. | 2012-01-26 |
20120021348 | TONER - In a toner formed of toner particles which include a colorant, a wax, and a binder resin containing a crystalline resin (a) primarily composed of a polyester, the crystalline resin has an endothermic peak temperature (Tp) in a range of 50° C. to 80° C., and in a viscoelasticity measurement of the toner, G″(Tp−10) is in a range of 5.0×10 | 2012-01-26 |
20120021349 | TONER - In differential scanning calorimetry of a toner, regarding a binder resin in the toner, (i) the peak temperature T | 2012-01-26 |
20120021350 | ELECTROPHOTOGRAPHIC TONER - A polyester resin for a toner, obtained by polycondensing a carboxylic acid component and an alcohol component, wherein the carboxylic acid component and/or the alcohol component contains an aromatic compound represented by the formula (Ia): | 2012-01-26 |
20120021351 | CONTINUOUS PROCESS FOR PRODUCING TONER USING AN OSCILLATORY FLOW CONTINUOUS REACTOR - The present disclosure provides for oscillatory flow continuous reactors suitable for use in forming emulsion aggregation toners. The reactor may include at least one receptacle being a flexible, tubular member. The reactor may also include a plurality of baffles disposed, at spaced apart intervals, along an interior space of the tubular member, each of the plurality of baffles including one or more orifices. Additionally, one or more fluids may flow through the tubular member. The oscillatory flow continuous reactor may be used in an emulsion aggregation process to produce toner particles. | 2012-01-26 |
20120021352 | TONER MANUFACTURING METHOD - Disclosed is a manufacturing method of toner which includes at least polyester resin and colorant, comprising the steps of: (A) dissolving, into an organic solvent, the polyester resin and ultrahigh molecular weight styrene resin in which a peak is present in a range larger than 500 thousands and smaller than 3 million in a molecular weight distribution, and preparing a binder resin solution; (B) dispersing the binder resin solution as binder resin solution droplets into an aqueous medium; (C) removing the organic solvent from the binder resin solution droplets, and preparing a resin particle dispersion; and (D) aggregating resin particles from which the organic solvent is removed and colorant particles containing the colorant with each other, and forming toner particles. | 2012-01-26 |
20120021353 | METHOD FOR PRODUCING TONER - Disclosed is a method for producing toner, comprising (1) mixing, with an aqueous medium, a resin solution of an organic solvent in which amorphous polyester resin having unsaturated dicarboxylic acid monomer units is dissolved, and forming an amorphous polyester resin particle dispersion; (2) adding a radical polymerization initiator to the amorphous polyester resin particle dispersion obtained in (1), cross-linking the amorphous polyester resin, and forming a cross-linked amorphous polyester resin particle dispersion; and (3) mixing at least the cross-linked amorphous polyester resin particle dispersion obtained in (2), with a crystalline polyester resin particle dispersion, aggregating cross-linked amorphous polyester resin particles and crystalline polyester resin particles, and forming toner particles. | 2012-01-26 |
20120021354 | COLORED CURABLE COMPOSITION, COLOR RESIST, INK-JET INK, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID-STATE IMAGE PICKUP DEVICE, IMAGE DISPLAY DEVICE, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, AND COLORANT COMPOUND AND TAUTOMER THEREOF - A colored curable composition including: at least one selected from the group consisting of a compound represented by the following Formula (1a) and a tautomer thereof; and at least one polymerizable compound, | 2012-01-26 |
20120021355 | COATING COMPOSITION FOR DUV FILTERING, METHOD OF FORMING PHOTORESIST PATTERN USING THE SAME AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE BY USING THE METHOD - Provided are a coating composition for deep ultraviolet (DUV) filtering during an extreme ultraviolet (EUV) exposure, the coating composition including about 100 parts by weight of a solvent including a first solvent (the first solvent being an alcoholic solvent); and about 0.05 parts by weight to about 5 parts by weight of a coating polymer having a degree of absorption of about 50%/μm or greater with respect to 193-nm incident light. | 2012-01-26 |
20120021356 | LITHOGRAPHIC PRINTING PLATE SUPPORT AND PRESENSITIZED PLATE - A presensitized plate bringing about the lithographic printing plate which exhibits a high resistance to scumming and in which formation of bulges causing image dropouts is suppressed is provided with the lithographic printing plate support which includes an aluminum plate and an anodized film of aluminum provided on the aluminum plate, and has a micropore extending in the anodized film in the direction of depth from a film surface opposite with a film surface facing the aluminum plate. The micropore is sealed at least partially on its inside with protrusions made of boehmite, and the protrusions made of boehmite which are located on the anodized film have a mean height of less than 15 nm. | 2012-01-26 |
20120021357 | POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME - A photosensitive insulating resin composition, comprising a polymer, a photosensitizer, and an amide derivative that is expressed by the following general formula (1); | 2012-01-26 |
20120021358 | PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE, DEVELOPER FOR LITHOGRAPHIC PRINTING PLATE PRECURSOR, AND REPLENISHER FOR LITHOGRAPHIC PRINTING PLATE PRECURSOR DEVELOPMENT - A process for making a lithographic printing plate is provided that includes (A) a step of preparing a lithographic printing plate precursor that includes above a support a photosensitive layer that includes (i) a binder polymer, (ii) an ethylenically unsaturated compound, and (iii) a radical polymerization initiator, (B) an exposure step of exposing the lithographic printing plate precursor, and (C) a development step of removing the photosensitive layer of a non-exposed area of the lithographic printing plate precursor, the development step (C) being carried out by means of a developer that includes an enzyme. There are also provided a developer for a lithographic printing plate precursor, the developer including (a) an enzyme and (b) a surfactant, and a replenisher for lithographic printing plate precursor development, the replenisher including an enzyme. | 2012-01-26 |
20120021359 | UPPER LAYER-FORMING COMPOSITION AND RESIST PATTERNING METHOD - A liquid immersion lithography upper-layer film-forming composition includes (A) a polymer that includes a structural unit (I) shown by the following formula (1), and (S) a solvent. R | 2012-01-26 |
20120021360 | METHOD OF MANUFACTURING LIQUID EJECTION HEAD - A method of manufacturing a liquid ejection head includes: exposing a negative organic resin layer to be a flow path forming member except for regions in which an ejection orifice and a fluid resistance portion are to be formed, respectively, and heating the negative organic resin layer and a flow path pattern to move a portion of the negative organic resin layer which corresponds to the fluid resistance portion toward a substrate; and exposing and developing the region of the negative organic resin layer in which the fluid resistance portion is to be formed. | 2012-01-26 |
20120021361 | RADIATION-PROTECTION DEVICE - A radiation-protection device is provided that includes a substrate and a surface structure formed on the substrate. The surface structure has an arrangement and interacts with radiation and the substrate to at least (a) substantially transmit or attenuate radiation at a wavelength and an energy below a threshold energy, and (b) substantially reflect radiation at the wavelength and an energy above the threshold energy. | 2012-01-26 |
20120021362 | Laser Imaging - A method of forming an image on a substrate, which comprises applying to the substrate an activatable colour forming compound wherein said activatable colour forming compound is initially unreactive but becomes reactive upon activation; activating said colour forming compound in the areas of the substrate where the image is to be formed, and, reacting the activated colour forming compound into its coloured form to produce an image. A substrate imaged using this method is also provided. | 2012-01-26 |
20120021363 | Co-Crystals and Their Use - A method of forming an image on a substrate by irradiation thereof, wherein the substrate comprises therein or thereon a co-crystal of a polymerisable unsaturated monomer and a spacing component, wherein the co-crystal is capable of undergoing a radiation-activated colour change reaction. A co-crystal of a diacetylene and a spacing component, whereby the reactivity of the diacetylene is reduced is also provided, together with a surface coating composition comprising this co-crystal. | 2012-01-26 |
20120021364 | METHOD AND SYSTEM FOR THE PRODUCTION OF A COMBUSTIBLE GAS FROM A FUEL - Method and system for the production of a combustible gas from a fuel, comprising the conversion of the fuel, at a temperature that is between 600 and 1000° C. and at a pressure that is lower than 10 bar, into at least a combustible gas that comprises CH | 2012-01-26 |
20120021365 | PREMIXING COMBUSTION DEVICE - In a premixing combustion device ( | 2012-01-26 |
20120021366 | Fuel composition comprising alkyl ester - Use of a composition comprising a base formulation of one or more alkyl esters of a C | 2012-01-26 |
20120021367 | Alternating Regenerative Furnace and Process of Operating Same - Alternating regenerative furnace and process of operating an alternating regenerative furnace, in which during the transition phase in which the respective regenerators switch between heat-recovery mode and pre-heating mode and vice-versa, the regenerator or regenerators which before the transition phase were in heat-recovery mode inject a mixture of flue gas and oxygen-containing gas into the combustion chamber of the furnace, which mixture combusts with fuel injected into the combustion chamber to produce heat. | 2012-01-26 |
20120021368 | MULTI-OPERATION WAFER BAKING SYSTEM - A multi-operation wafer baking system includes a chassis; a wafer loading device mounted on the chassis for laterally moving a wafer; a cruciform transportation device mounted on the chassis for receiving a wafer from the wafer loading device and including a base, an elevation platform, and a rotation platform mounted on the elevation platform and having four carrier arms for carrying wafers; an annular baking device mounted on the chassis to oppose the cruciform transportation device and including a central turn table, a plurality of wafer racks, and a plurality of baking tray assemblies functioning to receive wafers from corresponding wafer racks for performing a baking operation on the wafer; and an unloading device mounted on the chassis for receiving baked wafers. This system allows for baking wafers in a multi-operation manner to thereby improve throughput. | 2012-01-26 |
20120021369 | PERIODONTAL DISEASE SPACE MAINTENANCE DEVICES AND METHODS - Devices and methods are provided for maintaining space to treat a periodontal defect adjacent to a tooth, the devices and methods comprise a supporting structure comprising a pin, or suture or mesh having a body configured to extend over the periodontal defect and hold gingival tissue above the defect, the supporting structure having a first end configured to retain the supporting structure against at least a portion of the tooth and a second end configured to be attached or implanted in or on at least a portion of bone adjacent to the periodontal defect. The devices and methods provided maintain space between at least gingival tissue and the periodontal ligament and avoid compression of any bone replacement material in the defect. In some embodiments, the devices and methods provided can be removed from the healed periodontal defect without the need to cut into healed soft tissue. | 2012-01-26 |
20120021370 | BIODEGRADABLE STENTS AND METHODS FOR TREATING PERIODONTAL DISEASE - Biodegradable stents and methods for selectively guided tissue regeneration in treating a periodontal defect adjacent to a root of a tooth are provided. The biodegradable stents and methods comprise a coronal portion and a transverse portion or shelf, which reduce unwanted migration of gingival epithelium, gingival connective tissue, and soft tissue and enable the cementum and periodontal ligament cells to re-establish the periodontal ligament in a proper sequence resulting in a new periodontal attachment. | 2012-01-26 |
20120021371 | SPRAY NOZZLE AND DENTAL CLEANING SYSTEM - A dental cleaning system for providing a liquid jet for a mouth rinse includes a nozzle member, a nozzle attachment coupled to the nozzle member to define an axially extending chamber, a liquid duct configured to supply pressurized liquid to the chamber, a pressure piece disposed within the chamber, and a nozzle outlet extending out of the chamber and configured to discharge a cleaning jet. | 2012-01-26 |
20120021372 | DENTAL HAND PIECE WITH DIRECTIONAL GUIDER CROSS REFERENCE TO RELATED APPLICATION - A dental hand piece includes a reference line generator attachable to the face of a patient to generate a reference line in parallel to the top surfaces of the teeth of the patient, and a directional guider, for example, laser guider located on the front end of the hand piece body for generating a horizontal light beam for alignment with the reference line and a vertical light beam for indicating the hole-drilling position to help the dentist in drilling a hole perpendicular to the occlusal surface for accurate installation of a fixture to assure a successful dental implantation surgery. | 2012-01-26 |
20120021373 | Multi-Purpose Dental Instrument - A dental mirror tool having a body comprises a manifold disposed on the tool body proximate the mirror, a plurality of output ports disposed in an outlet side of the manifold and disposed to emit streams of light and fluid and air or suction toward a predetermined target, and a selection system for selecting the light, fluid, or air or suction emitted toward the predetermined target. In another aspect, a method for directing streams of light, fluid, air, or suction toward a target during a dental procedure, comprising the steps of attaching a manifold having output orifices for light, fluids, air, or suction to a body of the tool; connecting the orifices to sources of light, fluid, air, or suction; and controlling a substance emitted from the orifices to be directed toward the target. | 2012-01-26 |
20120021374 | OSCILLATING SPRAY TIP FOR ORAL IRRIGATOR - An oral irrigator tip defines a main fluid passage and first and second side fluid passages on a opposite sides of the main fluid passage. Each side fluid passage has an inlet and an outlet both in fluid communication with the main fluid passage. First and second island structures may be formed between the main fluid passage and respective side fluid passages. Fluid flow through the main fluid passage is drawn to sidewalls of the islands due to the Coanda effect. At least a portion of the fluid stream entering the main fluid passage is diverted through the first and second side fluid passages to create feedback loops that push the fluid flow through the main fluid passage alternately from side to side. An oscillating fluid stream is thereby delivered from the oral irrigator tip. | 2012-01-26 |
20120021375 | DEVICES AND METHODS FOR COLLECTING AND ANALYZING FLUID SAMPLES FROM THE ORAL CAVITY - Devices for collecting a fluid sample from the oral cavity, the device including a mouthpiece that includes a chamber, the chamber including front and rear inner walls; and means for collecting the fluid sample from the oral cavity; and methods of collecting and analyzing samples of fluid from the oral cavity, including the steps of placing the device in the oral cavity, collecting the fluid sample and conducting an analysis of the fluid sample. | 2012-01-26 |
20120021376 | GUTTA-PERCHA REMOVER - A gutta-percha remover suitable for removing gutta-percha and having flexibility with good compliancy to curvature of a root canal and superior removing capability for forming a sufficient gap between the gutta-percha and the root canal wall is provided. | 2012-01-26 |
20120021377 | ELECTRIC IMPLANT TORQUE WRENCH - An electric implant torque wrench includes a main unit, having a torque generating mechanism for outputting a torque and a control knob for adjusting and setting the torque, a handle having a flexible tube connected to the main unit for receiving the torque outputted by the main unit, and a clutch mechanism connected to the handle for receiving the torque outputted by the main unit for rotating a rotary tip to drive a dental implant into a patient's gum. The clutch mechanism stops the rotary tip from rotation when the torque outputted by the main unit reaches the value set by the control knob during installation of the dental implant. | 2012-01-26 |
20120021378 | DENTAL PROSTHETIC AND RESTORATION REMOVAL SYSTEM AND METHOD - A system for removing dental prosthetics and restorations effectively and efficiently without damaging the dental prosthetic or restoration and with minimal discomfort to a patient is disclosed. The system features central holder designed for receiving and securely supporting a single or plurality of support arms in a spaced apart arrangement, whereby each support arm is capable of supporting an adjustable and pivoting attachment designed to adhesively engage and remove a dental prosthetic and restoration with the application of force. The system also features a plurality of independent attachments that can be used to adhesively engage and effectively remove a dental prosthetic and restoration with the application of force. | 2012-01-26 |
20120021379 | PERIODONTAL SCALER - A periodontal scaler is provided, comprising an arcuate shank and an arcuate blade. The arcuate blade being designed to conform to the roughly cylindrical surfaces found on the roots of teeth. This conforming feature of the instrument's blade increases its cleaning efficiency by maximizing contact between the blade's surface and the root, and guiding the instrument along the root by holding its convex edges within the concave shape of the blade. | 2012-01-26 |
20120021380 | AREA-SPECIFIC DENTAL INSTRUMENT - An area-specific dental instrument is provided, which comprises an arcuate S-shaped shank and an arcuate blade further comprising a sharpened convex surface. This instrument can be capable of cleaning plaque and calculus from the lingual surfaces of anterior teeth and concave surfaces between teeth at the cemento-enamel junction. | 2012-01-26 |
20120021381 | DENTAL IMPLANT AND DENTAL COMPONENT CONNECTION - A dental implant, components, and kit are provided. The implant can comprise a body, attachment means for attaching the implant to bone, and a recess. The recess can be disposed within the body and open towards a proximal end thereof. The recess can comprise a proximally-disposed receiving chamber and a distally-disposed threaded chamber. The receiving chamber can comprise an interlock chamber, which can be disposed at a distal end of the receiving chamber and have a polygonal cross-section. The implant can be multi-functional such that components for various dental prostheses and procedures can be provided having portions that can, for example, engage the interlock chamber of the implant, mate with the receiving chamber of the implant, and/or mate with the proximal end the implant for supporting the prosthesis and/or facilitating the procedure. | 2012-01-26 |
20120021382 | ACCESSORY HEAD FOR A POWERED TOOTHBRUSH AND TOOTHBRUSH INCORPORATING THE SAME - A replaceable accessory head for a powered toothbrush. The user selects one of a plurality of dental care accessory assemblies for flossing, brushing teeth, or for stimulating the gums. That assembly is engaged with the head which in turn is engaged with the handle and is locked thereto. This locking motion also causes the assembly to become locked to the head and the assembly may then be used for its intended purpose. A vibratory mechanism in the handle is activated causing vibration in the accessory assembly and thus improving the flossing, brushing or gum stimulation motions. When the assembly is worn out or when a different dental hygiene task is to be undertaken, the user detaches the head from the handle, thereby simultaneously unlocking the accessory assembly from the head. The assembly is then disengaged and is replaced by a different accessory assembly. | 2012-01-26 |
20120021383 | Radically Curable Urethane Dimethacrylates and Compositions Thereof for Tougher Dental Prosthetics - A radically curable polyurethane composite for dental restorations, including provisional restorations, includes polyurethane dimethacrylate prepolymers that have at least one flexible unit within a polyurethane dimethacrylate backbone, and one or more dimethacrylate monomers. Composite materials made with polyurethane dimethacrylate prepolymers of the invention exhibit superior and optimal properties of flexural strength and deflection-at-break relative to conventional dental resin composites. Composite materials of the invention also provide improved melt-resistance in response to the heat of grinding or finishing, thereby improving the fit of restorations made from the composite and preserving the finishing instruments. Methods of treating a tooth using the radically curable polyurethane composite and methods of making the polyurethane dimethacrylate prepolymers with flexible units is also provided. A kit including the radically curable polyurethane composite is also described. | 2012-01-26 |
20120021384 | CHARACTERIZATION OF AN ANTIBIOTIC IMREGNATED DELIVERY SYSTEMS AS AN INTRACANAL MEDICAMENT IN ENDODONTIC THERAPY - Endodontic fibers comprising a biocompatible polymer vehicle permeable to medicaments, or combinations of medicaments, wherein the biocompatible polymer vehicle comprises one or more biocompatible and/or biodegradable polymers are described. Such fibers can be used, for example, in a method for the local delivery and sustained release of medicaments to periodontal or intracanal treatment sites. Endodontic fibers described include periodontal fibers and intracanal fibers. | 2012-01-26 |
20120021385 | Celestial weapons orientation measuring system - A celestial weapons orientation measuring system. The system includes a miniature celestial direction detection device. The device includes an inclinometer, a camera for imaging at least one celestial object and a processor programmed with a celestial catalog providing known positions at specific times of at least one celestial object and algorithms for automatically calculating target direction information based on the inclination of the system as measured by the inclinometer and the known positions of the celestial object as provided by the celestial catalog and as imaged by the camera. Similar to the training technique discussed in the background section, the pretend enemy wears a GPS detector and transmitter, and a computer system is preferably provided which determines when a trigger-pull results in a “casualty”. Preferred embodiments also include an inertial navigation sensor including a magnetic compass and a memory-based optical navigation system that permits continued operation on cloudy days and even in certain in-door environments. | 2012-01-26 |
20120021386 | METHOD AND APPARATUS FOR PROVIDING INFORMATION ABOUT A VEHICLE - Embodiments of this invention relate to a method and apparatus for providing information about a vehicle for training a driver. Vehicle data is received from a vehicle data gathering mechanism ( | 2012-01-26 |
20120021387 | PAINT SET - Provided is a paint set that can allow optimal colors to be easily selected, mixed and arranged and, at the same time, can attain a learning effect about three attributes of colors or a hue circle even during work production. A plurality of chromatic color paints each having a hue are arranged circularly in a storage case to constitute a hue circle. | 2012-01-26 |
20120021388 | SYSTEM AND METHOD FOR WEIGHT MANAGEMENT - A system and method for weight management and loss is provided. The system and method regulate the quantity and constitution of the food and the system and method regulate the speed at which a meal is consumed so as to trigger a natural satiety response. In one aspect of the invention there is provided a timer ( | 2012-01-26 |
20120021389 | INTERACTIVE IMMERSION SYSTEM FOR MOVIES, TELEVISION, ANIMATION, MUSIC VIDEOS, LANGUAGE TRAINING, ENTERTAINMENT, VIDEO GAMES AND SOCIAL NETWORKING - This invention is an apparatus and a method for language training and general entertainment and role-playing. It employs a digital processing system plays back audio or audio-visual program material, using special software to selectively direct the audio of this playback through the system's speakers or a headset, with the user taking the headset audio—in particular speech—as a model and prompt to repeat this speech. The user plays the role of the speaker in the program material, and the software further permits the user to record, in audio or audio-video, her dubbing efforts along with the program material, producing a version of the program material with the user's voice recorded in place of, or in conjunction with, the voice of a character in the program material. The user's recorded performance can also be overlaid onto the original program material. | 2012-01-26 |
20120021390 | Method and system for developing language and speech - A method, system and apparatus for developing concepts, language and speech in language learning disabled and generally learning disabled subjects. The approach attempts to build associations between the various implementations of language, namely, visual, oral, aural and written language within the subject. The technique utilizes the subject's main strengths, often the visual sense and develops language by building on that strength, gradually progressing to spoken and heard language. Graphically rich content is sued to convey the concepts to the subject. The disclosed techniques may be implemented using a computer program. | 2012-01-26 |
20120021391 | NEUROCOGNITIVE AND PSYCHOMOTOR PERFORMANCE ASSESSMENT AND REHABILITATION SYSTEM - A file system storing an executive program and a plurality of modules such that when the executive program is executed by a processor the executive program controls the plurality of modules. The modules include a plurality of test modules for executing a specific individual test to test a cognitive attribute of a user; a plurality of test batteries having one or more specified test modules, at least one registration module for registering each of the plurality of users; a plurality of interpretive modules for interpreting results of the test batteries; and at least one report module for immediately generating a cognitive status report for reporting the test battery results as determined by the plurality of interpretive modules. | 2012-01-26 |
20120021392 | LIFE SKILLS TOOL KIT AND METHOD - The Life Skills Tool Kit is a series of twelve key life skills in a multimedia format. Designed to convey life skills development information from a caregiver to a young child, in order for the child to listen, learn, practice and own positive habits and winning behaviors. Each life skill in the series contains a; DVD, coloring sheet, recognition sticker, reward card, practice board(s), reminder poster, and instruction sheets (with twelve indicia characters). The digital content is age appropriate information in digital storybook format which features puppets, animation and music. This evidenced based Life Skills Tool Kit is a unique learning method. | 2012-01-26 |
20120021393 | Method for Operating a Training Device and Training Device - A method for operating a training device is provided. According to the method, a property of a user using the training device during a training session is automatically determined, and a fitness level of the user is automatically determined from the user property. Based on the fitness level of the user a performance of a virtual opponent is automatically defined, and information representing the performance of the virtual opponent is output to the user. | 2012-01-26 |
20120021394 | METHODS FOR PHYSIOLOGICAL MONITORING, TRAINING, EXERCISE AND REGULATION - A computer assisted method for treating pain in a subject comprising measuring activity of one or more internal voxels of a brain of said subject associated with pain; communicating instructions to said subject which modulate activity of said voxel; and training said subject to control said internal voxel. | 2012-01-26 |
20120021395 | EDUCATIONAL SYSTEM FOR DENTAL PROFESSIONALS - An education system is disclosed. Unique interactive interfaces can give a user random access to patient data while taking an examination. Examination formats can include an item sequence format, which prompts a user to select and order proper treatments. A treatment map examination format can prompt a user to select a treatment and where to apply it. A dental treatment map can be used to map treatments to teeth surfaces, and a course authoring tool can allow a user to create a course, examinations, and scoring metrics. | 2012-01-26 |
20120021396 | SYSTEM AND RELATED METHOD FOR INSTRUCTING PRACTITIONERS RELATIVE TO APPROPRIATE MAGNITUDE OF APPLIED PRESSURE FOR DENTAL PROCEDURES - System and method for teaching a dental practitioner an appropriate pressure to apply during a dental procedure. The system includes a dental tool for use in a dental procedure and a substrate including a coating of a removable scratch-off material. The scratch-off material is adhered to the substrate so as to have an adherence strength that is specifically configured so that the scratch-off material coating is removable from the substrate by manipulating the dental tool against the scratch-off material coating upon application of a minimum threshold pressure that is substantially equal to that to be applied during a selected actual dental procedure. In this manner, an inexperienced practitioner is able to learn the appropriate magnitude of pressure to be applied during a procedure (e.g., application and burnishing of a hemostatic composition into bleeding soft tissue) in a non-threatening environment without having to actually work on a live, bleeding patient. | 2012-01-26 |
20120021397 | Model Human Eye and Face Manikin for Use Therewith - A model human eye that is structurally suited for practicing surgical techniques, including extraocular muscle resection and recession, is presented. The model eye comprises a hemispherical-shaped, bottom assembly having multiple retinal layers and a hemispherical-shaped, integrally molded top assembly having a visually transparent cornea portion surrounding a visually opaque sclera portion. The model eye further comprises an annular iris, a lenticular bag, an anterior chamber having a first fluid disposed therein, and a posterior chamber having a second fluid disposed therein. The model human eye further comprises a cylindrical member extending outwardly from the sclera portion, where the cylindrical member mimics an optic nerve, and a cone-shaped elastomeric assembly attached to a distal end of the cylindrical member and having four elastomeric members extending outwardly, where a distal end of each elastomeric member is attached to the sclera portion, and where each of the elastomeric members mimics a rectus muscle. | 2012-01-26 |
20120021398 | SYSTEM AND METHOD FOR DETECTING UNAUTHORIZED COLLABORATION ON EDUCATIONAL ASSESSMENTS - A collaboration detection system and a method for detecting collaboration amongst a class of two or more students in answering a plurality of problems of an assessment administered to the students are provided. The system includes a tangible processor and a memory with instructions to be executed by the tangible processor. The processor executes the instructions for accessing granular assessment data associated with each student. The granular assessment data includes an independent determination of correctness of the answer submitted by the student for each respective problem of the plurality of problems of the assessment. The processor then executes the instructions for determining for each combination of students of the class of students the number of problems for which it was determined that the same problem was answered incorrectly by all of the students of the combination of students. | 2012-01-26 |
20120021399 | METHOD AND SYSTEM FOR DEVELOPING AND ADMINISTERING SUBJECT-APPROPRIATE IMPLICIY-ASSOCIATION TESTS - The current application is directed to developing and administering subject-appropriate ITAs. The various to developing and administering subject-appropriate ITAs evaluate many aspects of ITA content, content presentation, and administration with regard to particular categories of test subjects in order to develop subject-appropriate ITAs (“SAITAs”) and to administer SAITAs appropriately to the categories of test subjects for which the tests are developed. Aspects of SAITA presentation and administration that are evaluated include input devices, presentation formats, presentation language, presentation media, colors used in presentation of tutorials and stimuli, words, pictures, and symbols used in a presentation of tutorials and stimuli, the pace and length of various portions of SAITAs, human vs. computer administration of SAITAs, presentation of feedback to test subjects during SAITAs, ITAs and many other aspects of ITA content, content presentation, and administration. SAITAs employ systematic methods for both development and administration of SAITAs. | 2012-01-26 |
20120021400 | MULTI-DIRECTION BOARD AND ACCESSORY INTERLOCK SYSTEM - A modular system is described and claimed featuring one of numerous connector embodiments having a plurality of the same or different component channels for providing a user flexibility in the types and arrangements of modular components for the office space. The connectors may have channels on one or more of a plurality of faces of the connector—front, bottom, back and top, and the components have complimentary configurations for slidable engagement with the channels of the connectors. | 2012-01-26 |
20120021401 | DISPOSABLE CARTRIDGE FOR AUTOMATIC AND CONTINUOUS WATER QUALITY MONITORING - A disposable cartridge for use in assaying an analyte in an automated water quality monitoring analyzer comprising: (a) a platform; (b) array of containers for separately containing at least one reagent, a buffer and a so freeze dried preparation of luminescent bacteria, said containers being mounted on said platform; (c) reaction chamber mounted on said platform and configured for being moved between said containers, such that said reagent, said buffer and said freeze dried preparation of luminescent bacteria are conveyed to said reaction chamber in a predetermined sequence such that light detectable by said analyzer is emitted; (d) fluid transferring means for fluid transfer and mixing between said containers, reaction chamber, and analyzer; (e) conveying means for moving said cartridge to predetermined positions within said automated water quality monitoring analyzer for enabling analysis of said analyte. | 2012-01-26 |
20120021402 | BIOSENSOR APPARATUSES AND METHODS THEREOF - A biosensor has one or more field effect transistors each comprising a source region and a drain region separated by a channel region and a gate positioned offset and spaced from the channel region. The biosensor also has one or more molecular probes coupled to at least one of the channel region and the offset gate, the one or more molecular probes configured to mate with at least one target. A method for detection of a target is also disclosed. One or more targets are immobilized as an electric field shunt between an offset gate and a channel region for one or more biosensors. A target measurement value is determined in proportion to a number of the one or more biosensors having the electric field shunt. | 2012-01-26 |
20120021403 | Human Endogenous Retrovirus with Foamy-Like Properties and Uses Thereof - The invention relates to the discovery of a human endogenous retrovirus (HERV) family, Type I HERV-K (HML-2) which appear to be active in vitro and in vivo, infectious, and which have the have the salient features and properties of foamy retroviruses. Based on its natural replication in humans, and that it protects the host from viral and tumor transformation, this non-pathogenic endogenous virus could be developed as a replication competent gene therapy vector. It also is expected to have much higher efficacy than other vectors as it crosses the bloodbrain barrier and infects almost all cell types in the host (proliferating or not). It may naturally lyse tumor cells or infected cells, and thus could even be used without genetic modification. Of course, this vector could be used in traditional ways with it ability to replicate genetically removed. In addition to its value as a vector, as it is reactivated with infection, its detection could also be used to monitor the safety of gene therapy (irrespective of vector type used), as well as other biological therapies including vaccination, blood transfusion, transplantation and xenotransplantation. Finally it may be used to screen for new therapeutic and prophylactic treatments for a wide variety of diseases. | 2012-01-26 |
20120021404 | Method for Diagnosis and Monitoring of Viral Infection by Analysis of Viral Transrenal Nucleic Acids in Urine - The present invention relates to methods for diagnosis or monitoring of viral infection by detecting the presence of transrenal viral nucleic acids or nucleic acids of viral origin in urine sample, with or without isolation of nucleic acids from a urine sample. The analysis of the nucleic acids is performed through hybridization of the nucleic acids with specific probes, or through a chain amplification reaction with specific primers. The methods are applicable to all viral pathogenic agents, including RNA, DNA, episomal, or integrated viruses. | 2012-01-26 |
20120021405 | Single Chain Antibody for the Detection of Noroviruses - The present invention concerns compositions and methods for detecting Norovirus or Norovirus particles. In particular, the present invention encompasses antibodies for detecting Norovirus or Norovirus particles, including, for example, monoclonal antibodies that have broad specificity of binding to various genogroups of norovirus. | 2012-01-26 |
20120021406 | METHOD FOR MONITORING A STERILIZATION PROCESS - The disclosed invention relates to a method for monitoring a sterilization process. The method comprises: (A) exposing an article to be sterilized and a biological indicator to a sterilization medium during a sterilization process, the biological indicator comprising a cell with a plasma membrane; and (B) measuring the membrane potential of the cell to detect the viability of the cell. | 2012-01-26 |
20120021407 | Methods and Devices for Rapid Urine Concentration - The present invention provides a device for the concentration of one or more target analytes contained in a urine sample. The device comprises a tube comprising an upper portion defining an opening for receiving the urine sample and a lower tapered portion terminating in collection reservoir. The tube contains a predetermined amount of a particulate binding agent which specifically binds the one or more target analytes and of a predetermined amount of a binding buffer. The device comprises means for seating the opening of the tube. The present invention further provides methods and kits for concentrating one or more target analytes in murine sample. | 2012-01-26 |
20120021408 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS - This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides. | 2012-01-26 |
20120021409 | Common Light Chain Mouse - A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making light chain variable regions in mice, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, are provided. | 2012-01-26 |
20120021410 | TRIGGERED MOLECULAR GEOMETRY BASED BIOIMAGING PROBES - The present embodiments relate to engineering imaging probes based on “triggered molecular geometry.” Upon detection of a molecular signal, nucleic acid hairpin monomers assemble an imageable molecular shape with prescribed geometry. In some embodiments the prescribed shape can be imaged directly. In some embodiments, the prescribed shape can serve as a spatial organizer or amplification scheme for other imaging entities, such as fluorophore and fluorescent proteins. | 2012-01-26 |
20120021411 | AUTOMATED HIGH-THROUGHPUT SEED SAMPLER AND METHODS OF SAMPLING, TESTING AND BULKING SEEDS - A seed sampling system includes a seed transport configured to hold multiple individual seeds together as a group and transport the multiple individual seeds together as the group, and to allow the multiple individual seeds to be oriented, substantially simultaneously, while the multiple individual seeds are being held in the seed transport. The seed sampling system also includes a seed sampling subsystem configured to remove tissue from the oriented multiple individual seeds. And, a method for removing tissue from the multiple individual seeds includes loading the multiple individual seeds in the seed transport, orienting the multiple individual seeds in the seed transport substantially simultaneously, and removing tissue from the oriented multiple individual seeds. | 2012-01-26 |
20120021412 | Compositions and Methods for Detecting Pathogen Specific Nucleic Acids in Urine - The invention is based upon the discovery that small nucleic acids from non-viral pathogens are able to cross the kidney and are present in urine of a subject when the subject is infected with the non-viral pathogen. These transrenal DNAs are especially prevalent at smaller sizes under about 300 bp. Thus the invention provides compositions and methods for the diagnosis of infection of a subject with non-viral pathogens through the detection of transrenal nucleic acids from those pathogens in the urine of the subject. | 2012-01-26 |
20120021413 | Method for Detecting Mutation in Exon 12 of JAK2 Gene, and Nucleic Acid Probe and Kit Therefor - A probe for detecting a polymorphism in exon 12 of the JAK2 gene, the probe comprising at least one of the oligonucleotides in (a) to (c) below:
| 2012-01-26 |
20120021414 | DIAGNOSTIC MARKERS OF IMMUNOSENESCENCE AND METHODS OF USE THEREOF - Embodiments of the present invention provide diagnostic markers of immunosenescence and methods of identifying individuals with impaired immune function based on a combination of such markers obtained from various analyses, primarily from blood, testing immune function including the analysis of immune cell subset frequencies, gene expression, cytokine and chemokine levels, and signaling responses to stimulation with cytokines (‘cytokine response’). Particular combinations of markers can predict with high accuracy whether an individual will respond to active vaccination and become protected against recurring diseases. | 2012-01-26 |
20120021415 | Methods for Determining Response to Neoadjuvant Therapy and Survival Using MicroRNA-10b - The present invention provides methods for determining response to neoadjuvant therapy and metastasis-free survival in pancreatic ductal adenocarcinoma based upon the level of microRNA expression and optionally the presence of a protein cancer cell marker in biological samples such as formalin-fixed paraffin-embedded specimens using in situ hybridization and optionally an immunohistochemical assay. | 2012-01-26 |
20120021416 | BIOLAYER INTERFEROMETRY MEASUREMENT OF BIOLOGICAL TARGETS - Disclosed are methods and compositions for the ultrasensitive detection of oligonucleotides, proteins, protein complexes, biomolecules, and infectious agents using a peroxidase driven deposition of substrates onto interferometry capable biosensors, coupled to the specific recognition of the target molecules. More specifically, methods are disclosed to specifically immobilize biological target molecules onto the surface of interferometry capable biosensors and to associate the target molecules with peroxidase enzymes. Through the peroxidase driven deposition of substrates onto the interferometry capable biosensors there is the ability to achieve ultrasensitive detection and quantification of specific target molecules. | 2012-01-26 |
20120021417 | DOPAMINERGIC NEURON PROLIFERATIVE PROGENITOR CELL MARKER Nato3 - The present invention is a probe, a primer, and an antibody, for detecting a dopaminergic neuron proliferative progenitor cell. According to the present invention, there is provided a polynucleotide probe and a polynucleotide primer for use in the detection or selection of a dopaminergic neuron proliferative progenitor cell, which can hybridize with a polynucleotide consisting of a nucleotide sequence of a Nato3 gene, or a complementary sequence thereto, and an antibody against a Nato3 protein, or a part thereof for use in the detection or selection of a dopaminergic neuron proliferative progenitor cell. | 2012-01-26 |
20120021418 | GENE THAT IMPARTS OXYGEN RESISTANCE AND APPLICATION THEREOF - To provide a gene useful for imparting oxygen resistance to a microorganism and use of the gene. | 2012-01-26 |
20120021419 | Analyzing System, Analyzing Apparatus, Container, Analyzing Method, Program, and Recording Medium - An analyzing system that enables further expansion of analysis items and automation of analysis. In the analyzing system for performing an analysis using container | 2012-01-26 |
20120021420 | Synthetic siRNA Detection Method - A method for accurately and easily detecting a synthetic siRNA, for example, a siRNA in which the 3′ end is DNA, and a kit used for the method are provided. The present invention relates to a method for detecting a siRNA in which the 3′ end is DNA, comprising: (a) adding polydeoxyadenosine to the 3′ DNA end of at least one strand of the siRNA to be detected to produce a polydeoxyadenosine-added RNA; (b) annealing a polydeoxythymidine primer having a tag sequence at its 5′ side to the polydeoxyadenosine-added RNA and synthesizing DNA from the primer by a reverse transcription; and (c) detecting the DNA synthesized in (b). | 2012-01-26 |
20120021421 | Bacterial DNA as Markers of Cardiovascular and/or Metabolic Disease - The present invention relates to an in vitro method for predicting and/or diagnosing a cardiovascular and/or metabolic disease in a subject, which method comprises determining the concentration of bacterial DNA in a biological sample of said subject, together with degenerated primers for predicting and/or diagnosing a cardiovascular and/or metabolic disease in a subject. | 2012-01-26 |
20120021422 | METHODS FOR PROCESSING SAMPLES IN A CLOSED CONTAINER - A system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and/or other sample manipulation device can be attached to the inside of the barrier, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device. The barrier can be flexible, and allow the robotic arm to move the pipette head throughout the work area of the tray. All samples, reagents, pipette tips and other tools or devices for processing nucleic acid samples may remain within the closed compartment provided by the container during processing. | 2012-01-26 |
20120021423 | CONTROLS AND CALIBRATORS FOR TESTS OF NUCLEIC ACID AMPLIFICATION PERFORMED IN DROPLETS - System, including methods and apparatus, for performing droplet-based tests of nucleic acid amplification that are controlled and/or calibrated using signals detected from droplets. | 2012-01-26 |
20120021424 | Device and Method for Thermal Cycling - A thermal cycling device for performing nucleic acid amplification on a plurality of biological samples positioned in a sample well tray. The thermal cycling device includes a sample block assembly, an optical detection system, and a sample well tray holder configured to hold the sample well tray. The sample block assembly is adapted for translation between a first position permitting the movement of the sample well tray into alignment with sample block assembly, and a second position, upward relative to the first position, where the sample block assembly contacts the sample well tray. A method of performing nucleic acid amplification on a plurality of biological samples positioned in a sample well tray in a thermal cycling device is also provided. | 2012-01-26 |
20120021425 | MUTATIONS IN THE BCR-ABL TYROSINE KINASE ASSOCIATED WITH RESISTANCE TO STI-571 - The invention described herein relates to novel genes and their encoded proteins, termed Mutants Associated with Resistance to STI-571 (e.g., T315I Bcr-Abl), and to diagnostic and therapeutic methods and compositions useful in the management of various cancers that express MARS. The invention further provides methods for identifying molecules that bind to and/or modulate the functional activity of MARS. | 2012-01-26 |
20120021426 | METHOD OF DETECTING TARGET SUBSTANCE - Provided are a method of detecting a target substance and the like using a probe with a simple design for target substance detection. | 2012-01-26 |
20120021427 | Methods For Rapid Forensic DNA Analysis - The present invention provides methods and primer pairs for rapid, high-resolution forensic analysis of DNA and STR-typing by using amplification and mass spectrometry, determining the molecular masses and calculating base compositions of amplification products and comparing the molecular masses with the molecular masses of theoretical amplicons indexed in a database. | 2012-01-26 |
20120021428 | METHOD FOR DIAGNOSIS OF CANCER AND MONITORING OF CANCER TREATMENTS - The present invention relates to a method for cancer diagnosis and for monitoring cancer treatments based on the analysis of the DNA fragmentation pattern of repetitive elements (preferably LINED or multi copy genes (preferably U1 RNA) identified in body fluid samples isolated from cancer patients. | 2012-01-26 |
20120021429 | Compositions, Products, Methods And Systems to Monitor Water And Other Ecosystems - Disclosed are compositions, products, methods and systems for monitoring ecosystems, such as bodies of water, for a parameter of the ecosystems, such as the presence or absence of mercury. In one embodiment, the product may include a plurality of oligonucleotides immobilized at known locations on a substrate as an array, such that each location on the array is an oligonucleotide having a sequence derived from a single, predetermined operational taxonomic unit (OTU) and wherein at least one sequence on the array is associated with the presence or absence of mercury. The sequences immobilized on the array may be from known, or unknown organisms. Also disclosed are methods for identifying and isolating bioindicators diagnostic of ecosystem parameters, such as whether mercury is present. The compositions, products, methods and systems of the invention may be used for rapid, and continual monitoring of ecosystems for parameters of interest, such as the presence or absence of mercury. | 2012-01-26 |
20120021430 | FUNCTIONAL LIPID CONSTRUCTS - The invention relates to methods for effecting qualitative and quantitative changes in the functional moieties expressed at the surface of cells and multi-cellular structures, and functional lipid constructs for use in such methods. In particular, the invention relates to functional lipid constructs and their use in diagnostic and therapeutic applications, including serodiagnosis, where the functional moiety is a carbohydrate, peptide, chemically reactive group, conjugator or fluorophore. | 2012-01-26 |
20120021431 | DIAGNOSTIC METHODS USING BNP - The present invention provides a new method and kit for determining the overload of atrium or ventricle in a subject comprising at least a step of measuring levels of proBNP-108 in a sample from the subject. The disclosed methods and kits are useful, for example, in the diagnosis, prevention and/or treatment of cardiac diseases, particularly heat failure, aortic stenosis, aortic regurgitation, mitral stenosis, mitral regurgitation, and atrial fibrillation. | 2012-01-26 |
20120021432 | Phosphorylated NF45 Biomarkers, Antibodies And Methods Of Using Same - The present invention relates to isolated phosphorylated NF45 peptides and isolated phosphorylation site-specific antibody or antigen-binding portion thereof that specifically binds a phosphorylated NF45 protein. The present invention also relates to methods of utilizing these antibodies to determine the therapeutic efficacy of a candidate compound and methods for screening for candidate compounds that increase the phosphorylation of NF45 protein in a cell. | 2012-01-26 |
20120021433 | REDUCING OPTICAL INTERFERENCE IN A FLUIDIC DEVICE - This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample. | 2012-01-26 |
20120021434 | METHOD FOR TREATING B CELL REGULATED AUTOIMMUNE DISORDERS - The invention relates to a method for treating B-cell regulated autoimmune disorders using compounds that modulate the activity of c-Rel. | 2012-01-26 |
20120021435 | DETECTION OF LIVING, CIRCULATING, OR DISSEMINATED CELLS OR CELL CONSTITUENTS IN BLOOD OR BONE MARROW FOLLOWING FILTRATION OF BLOOD - A method is disclosed for detecting circulating cells in a body fluid sample. In at least one embodiment, the method includes: filtering the body fluid sample through a porous membrane; transferring the porous membrane with the cells located thereon as filter residue to a cell culture vessel, wherein one surface of the cell culture vessel is coated with a first antibody which is directed to a first cell-specific marker; incubating the porous membrane in the cell culture vessel with a cell culture medium, wherein cell-specific markers released by any cells present are bound by the first antibody to produce a bound first cell-specific marker on the surface coated with the first antibody; removing the porous membrane with the cells located thereon as filter residue from the cell culture vessel; detecting the bound first cell-specific marker on the surface coated with the first antibody. | 2012-01-26 |
20120021436 | Crystal structure of human alpha-N-acetylglucosaminidase - The present invention provides the three-dimensional structure of human α-N-acetylglucosaminidase (NAGLU) protein. This crystallographic information is useful in the identification and development of novel binding compounds of NAGLU, NAGLU mutants, for example, those associated with Sanfilippo syndrome type B (mucopolysaccharidosis III B (MPS III-B)), and other NAGLU family members (family 89 α-N-acetylglucosaminidase) which may modulate the activity and/or stability of mutated NAGLU. Such compounds may be useful for the treatment of Sanfilippo syndrome type B (mucopolysaccharidosis III B (MPS III-B)). | 2012-01-26 |
20120021437 | TETRANOR-PGDM/PGJM SPECIFIC IMMUNOGENS, ANTIBODIES, TRACERS, ASSAY KITS AND METHODS FOR MAKING SAME - Tetranor-PGDM/tetranor-PGJM-specific antibodies, immunogens used to generate them, the processes of their manufacture, and their uses in assay kits for detecting and quantifying tetranor-PGDM and tetranor-PGJM in biological fluids for determining biosynthesis of PGD | 2012-01-26 |
20120021438 | Method of Detecting Target, Method of Suppressing Increase in Background and Detection Apparatus - Provided are a method of detecting a target with high accuracy, a method of suppressing an increase in background, and a detection apparatus. | 2012-01-26 |
20120021439 | SERIAL MULTIPLE ANTIGEN COLOCALIZATION IN PARAFFIN-EMBEDDED TISSUE - The present invention provides a novel method called Sequential IMmunoPeroxidase Labeling and Erasing (SIMPLE) that enables the simultaneous visualization of at least five markers within a single tissue section. Utilizing the alcohol-soluble peroxidase substrate 3-amino-9-ethylcarbazole (AEC), combined with a rapid non-destructive method for antibody-antigen dissociation, the present application discloses the ability to erase the results of a single immunohistochemical stain while preserving tissue antigenicity for repeated rounds of labeling. The present invention also provides methods for visualizing multiple antigens simultaneously. | 2012-01-26 |
20120021440 | METHODS FOR TESTING LIGAND BINDING TO G PROTEIN-COUPLED RECEPTORS - The present invention relates to methods for testing for the binding of a ligand to a G Protein-Coupled Receptor. In particular, the methods of the invention are useful in high throughput screening for ligands which bind to G Protein-Coupled Receptors. | 2012-01-26 |
20120021441 | IN-PROCESS CONTROL IN A METHOD FOR PRODUCING EPO - The invention relates to a method for determining the isoform composition of erythropoietin, comprising the following steps:
| 2012-01-26 |
20120021442 | MARKERS FOR DETECTION OF COMPLICATIONS RESULTING FROM IN UTERO ENCOUNTERS - Described herein are biomarkers, such as protein biomarkers, which are diagnostic of and predictive for complications that result from an in utero encounter, such as an infection by the fetus, that can lead to premature birth (PTB). The biomarkers can be used to identify fetuses and newborns at risk for complications of PTB, such as (Early Onset Neonatal Sepsis) EONS, intra-ventricular hemorrhage (IVH) and other poor outcomes. | 2012-01-26 |
20120021443 | DIRECTIONAL SURFACE PLASMON COUPLED FLUORESCENCE AND CHEMILUMINESCENCE FROM THIN FILMS OF NICKEL, IRON OR PALLADIUM AND USES THEREOF - Nickel, iron and palladium thin films thermally evaporated onto glass supports are used to demonstrate surface plasmon coupled fluorescence (SPCF) and surface plasmon couple chemiluminescence (SPCC) over a broad wavelength range (400-800 nm) for potential assays or other detection systems. Nickel, iron and palladium thin films used in SPCF and SPCC convert otherwise isotropic emission into highly directional and polarized emission, an attractive concept for surface assays. The emission angles of detected emissions occur over a 10 degree range for tested emitted wavelengths. | 2012-01-26 |
20120021444 | METHOD FOR DIAGNOSIS OF CYSTIC FIBROSIS USING KL-6 LEVELS - The present invention provides a method for diagnosis of cystic fibrosis, the method comprising: measuring an amount of KL-6 in a sample of body fluid from a subject, and determining, based on the amount of KL-6 measured, the degree of presence of cystic fibrosis in the subject. | 2012-01-26 |
20120021445 | Pluripotent Stem Cells for Drug Induced Myopathy and Malignant Hyperthermia - The present invention relates to methods of identifying, collecting and isolating pluripotent stem cells, and compositions of purified stem cells for the diagnosis of susceptibility to drug induced myopathy (DIM) and malignant hyperthermia (MH). Specifically, the present invention provides methods of producing skeletal muscle myocytes from patient-specific stem cells, and methods for identifying susceptibility to DIM and MH in patient-specific skeletal muscle myocytes generated from patient-specific stem cells. The present invention also relates to methods, compositions and kits for screening drugs for DIM and MH risk. | 2012-01-26 |