03rd week of 2016 patent applcation highlights part 7 |
Patent application number | Title | Published |
20160015554 | COLOSTOMY APPLIANCE - The present invention discloses a colostomy appliance consisting of two pouches, in which one pouch is designed to collect the faecal waste, and the other pouch is designed to receive the above pouch. The first pouch can be easily inserted into the second pouch and removed from the second pouch when it is fully loaded by waste. The liner pouch is made of plastic material which is flushable and biodegradable. The outer pouch is made of laminated breathable PE and nonwoven material, allowing for increased comfort and functionality of collecting waste next to an individual's abdomen. The outer pouch is sprayed on the inside with odour control compound to mitigate the faecal odour. Both the two pouches are designed for ease of use. Wearers can easily carry and replace the inner pouch in public facilities and the materials used for the pouch are silent ensuring discreetness during movement. | 2016-01-21 |
20160015555 | TISSUE CROSSLINKING FOR TREATMENT OF SNORING AND OBSTRUCTIVE SLEEP APNEA - A method of treating snoring and/or OSA in a subject in need of such treatment. The method includes crosslinking proteins of the subject's soft palate tissue or pharynx tissue. The crosslinking can occur by contacting the soft palate or pharynx tissue with a crosslinking reagent. In addition, the crosslinking can occur without heating, contracting or denaturing of the tissue, or any combination thereof. | 2016-01-21 |
20160015556 | Cuspid and First Bi-Cuspid Bite Retainer for Sleep Apnea - A retainer with a block extending downwards from an otherwise generally flat surface is disclosed. The block corresponds to a region of one or more of the cuspids or pre-molars. A side block or other device on the upper retainer also abuts a wing or other abutment device of a lower retainer, causing the lower jaw to be pushed forward relative to the upper jaw and resting position (regular organic closing position) of the upper and lower jaw together. Thus, the upper teeth are pushed forward and a space is created between the teeth behind the (lower) block preventing an apnea during sleep. | 2016-01-21 |
20160015557 | Variable Stiffness Flexure - An intrauterine device includes a central support member, first and second internal flexures and first and second external flexures. The first and second internal flexures each include a first section having a first stiffness, a second section having a second stiffness, and third section having a third stiffness, wherein the second stiffness is more flexible than the first and third stiffness and wherein the first section of each internal flexure is coupled to the central support member. The first and second external flexures are coupled to the central support member and coupled to the third sections of the first and second internal flexures, the first and second external flexures in combination with the first and second internal flexures being configured to extend from a collapsed position parallel to the central support member to a deployed position flexing away from the central support member. | 2016-01-21 |
20160015558 | DEVICES AND METHODS FOR COOLING PATIENTS - A pneumatic cooling device including a housing having a first end and a second end. A handle extends from an outer surface of the housing. An inlet is positioned at substantially the first end of the housing and is configured to receive a supply of medical grade air into the housing. An outlet is positioned at substantially the second end of the housing and is configured to deliver the supply of medical grade air outside of the housing. A pathway extends through the housing between the inlet and the outlet and is configured to passively move the supply of medical grade air between the inlet and the outlet. | 2016-01-21 |
20160015559 | Heated Undergarment for the Treatment of Fibromyalgia - An undergarment for the treatment of Fibromyalgia is provided. The undergarment is shaped to be worn about the torso of a patient and the undergarment includes a plurality of electrical heating elements secured to the undergarment, each of the plurality of electrical heating elements positioned at a location substantially coincident with a Fibromyalgia trigger point of the patient. The use of the undergarment allows the patient to be active while continually receiving therapeutic treatment for the discomfort caused by Fibromyalgia. | 2016-01-21 |
20160015560 | METHODS TO IMPROVE THE PERFORMANCE OF THERMOELECTRIC HEATING/COOLING DEVICES - The present disclosure provides methods to improve the performance of heat exchangers used in thermoelectric cooling/heating devices, wherein improved heat conduction between heat exchanger and thermal exchange fluid is accomplished. Additionally, a method is disclosed to minimize the necessary delay used to protect the thermoelectric modules against thermal shock when switching from heat to cold, or vice versa. Thermal shock can damage thermoelectric modules when the direction of current passing through the modules is instantly switched. | 2016-01-21 |
20160015561 | Heatable and Coolable Therapeutic Device - A heatable and coolable therapeutic device provides a soothing sensation to areas of pain on a person's body. The device includes a first ball. The first ball is spaced from a second ball. Each of the first and second balls has a hollow interior. A spacer is coupled to and extends between the first ball and the second ball. The first ball, the second ball and the spacer define a cohesive unit. A heat-retentive material is positioned in the hollow interior of each of the first ball and the second ball. The heat-retentive material maintains a selectable one of an elevated temperature and a decreased temperature relative to ambient temperature over an extended period of time. | 2016-01-21 |
20160015562 | INTRAOCULAR LENS INSERTION DEVICE AND INTRAOCULAR LENS INSERTION SYSTEM - An intraocular lens insertion device includes: a plunger that extrudes a deformable intraocular lens into an eye along an extrusion axis, the deformable intraocular lens including an optical part and one or a plurality of support parts extending outward from a periphery of the optical part; an installation part in which the intraocular lens is installed in a state where at least one support part is placed closer to a proximal end side of the extrusion axis than the optical part; and an off-axis movement part that presses the support part of the intraocular lens installed in the installation part from a direction different from the extrusion axis to deform and move the support part. | 2016-01-21 |
20160015563 | SYSTEMS, METHODS, AND DEVICES FOR CANNULA INSERTION - A cannula insertion system configured to divide a cannula insertion process into a two-step process. The first step advances a needle portion a first distance and the second step advances the needle portion a second distance. The first step and the second step may be at different angles. At least one of the angles may be less than 90°. At least one of the steps may be mechanically assisted. | 2016-01-21 |
20160015564 | DRUG-DELIVERY PUMPS AND METHODS OF MANUFACTURE - Embodiments of method of manufacturing an implantable pump, including providing an upper layer comprising a dome structure for housing a drug chamber and a cannula in fluid communication with the drug chamber, providing a middle deflection layer adjacent the drug chamber, providing a bottom layer comprising electrolysis electrodes, and bonding the upper layer, middle deflection layer, and bottom layer to form the pump. | 2016-01-21 |
20160015565 | LASER PROBE WITH A REPLACEABLE OPTIC FIBER - A laser probe with a replaceable optic fiber may include a reusable handle, a reusable housing tube, a reusable handle adapter, a reusable machine adapter, and a replaceable optic fiber. The handle adapter may interface with a proximal end of the handle. The machine adapter may interface with a surgical machine. The replaceable optic fiber may include an optic fiber having a first optic fiber end and a second optic fiber end, a first connector, and a second connector. The optic fiber may be disposed within the first connector and the second connector. The first connector may be temporarily fixed within the handle adapter and the second connector may be temporarily fixed within the machine adapter. | 2016-01-21 |
20160015566 | EAR-ENGAGING AND EYE-COVERING HEAD ASSEMBLY - The present invention relates to an eye-protector assembly. The assembly includes arcuate-shaped protective cover. The assembly includes an eye-covering member pivotably connected to the protective cover. The protective cover is shaped to receive the eye-covering member when the eye-covering member is pivoted towards the cover. The assembly includes a pair of connector mechanisms for selectively coupling the protective cover to a hearing protector. | 2016-01-21 |
20160015567 | OPTICAL MICROPHONE FOR IMPLANTABLE HEARING INSTRUMENT - An implanted microphone is provided that allows for isolating an acoustic response of the microphone from vibration induced acceleration responses of the microphone. The present invention measures the relative motion between a microphone diaphragm, which is responsive to pressure variations in overlying media caused by acoustic forces and acceleration forces, and a cancellation element that is compliantly mounted within a housing of the microphone, which moves primarily in response to acceleration forces. When the microphone and cancellation element move substantially in unison to acceleration forces, relative movement between these elements corresponds to the acoustic response of the microphone diaphragm. This relative movement may be directly measured using various optical measuring systems. | 2016-01-21 |
20160015568 | EARPLUG AND PUMPING SYSTEMS - An earpiece, earphone, earbud or earplug includes an inflatable element operatively attached to a distal end by an inflation channel, and an anti-distal end of the inflation channel that provides a pressuring force via fluid transfer of a fluid to maintain an expansion of the inflatable element. The inflatable element can be pressurized to a gauge pressure range between 0.05 bar and 3.0 bar. In some embodiments, the inflatable element is pressurized to a gauge pressure range from 0.3 bar to 0.25 bar and maintains such gauge pressure range for at least 12 hours. In some embodiments, the inflatable element uses a material of a predetermined permeability for a given density of fluid and a given thickness of the inflatable element such that an inflation pressure drops from 1.2 atmospheres to 1 atmospheres in 8 hours after the inflatable element is pressurized to 1.2 atmospheres. Other embodiments are disclosed. | 2016-01-21 |
20160015569 | ANISOTROPIC DRAPES AND SYSTEMS - An anisotropic wound drape for treating a wound on a patient includes a flexible sheet for placing over a tissue site. The flexible sheet includes a first isotropic zone, and a second isotropic zone. The first isotropic zone and the second isotropic zone are configured to provide the flexible sheet with anisotropic stretching properties. The anisotropic drape may used as part of a reduced-pressure wound treatment system. Other systems and methods are also presented. | 2016-01-21 |
20160015570 | A CONFORMABLE MEDICAL DRESSING - The disclosed medical dressing is highly flexible and conformable over skin, while maintain strong adhesive securement to skin over extended periods of time. The dressing comprises a backing layer, support material, and a plurality of specifically placed slits in the support material, which allow for stretching and recovery of the backing layer. | 2016-01-21 |
20160015571 | REDUCED-PRESSURE DRESSINGS EMPLOYING TISSUE-FIXATION ELEMENTS - A reduced-pressure system for treating a tissue site on a patient includes a distribution manifold that adheres to a tissue site to allow retention without external support. The distribution manifold includes a porous member and a tissue-fixation element. The tissue-fixation element maintains the porous member substantially adjacent to the tissue site while a sealing member is applied. In one instance, the tissue-fixation element is a soluble adhesive that partially covers either the tissue-facing side of the porous member or a tissue-facing side of a fluid-permeable substrate layer that is on the tissue-facing side of the porous member. Other systems, distributions manifolds, and methods are presented. | 2016-01-21 |
20160015572 | TAMPON AND METHOD OF MAKING - A tampon has a pair of longitudinally extending side edges and an absorbent member. The absorbent member has an insertion area, a withdrawal area, and an intermediate area between the insertion area and the withdrawal area and an attachment area. The absorbent material has a plurality of fiber integrated nonwoven layers but are without fiber integration adjacent layers outboard of the attachment area. A withdrawal line extends from the withdrawal area and is attached to the absorbent member in the attachment area such that each of the plurality of absorbent layers is attached to an adjacent nonwoven layer in the attachment area. | 2016-01-21 |
20160015573 | Fluid Absorbent Surgical Device for Cannulas - A surgical device that absorbs fluid material on a surface of a cannula comprises a handle, and an absorbent portion coupled to a first end of the handle. The absorbent portion comprises a plurality of absorbent discs separated by at least one spacer. The plurality of absorbent discs and the at least one spacer are disposed about a post, and the at least one spacer is restrained from axial movement relative to the post. | 2016-01-21 |
20160015574 | WEARING ARTICLE AND MANUFACTURING PROCESS FOR THE SAME - A wearing article includes a front waist panel, a rear waist panel and a crotch panel having an absorbent structure wherein respective inner end edges of the front and rear waist panels cooperate with both side edges of the crotch panel extending in a longitudinal direction to define peripheries of a pair of leg-openings. The crotch panel is provided with a pair of elasticized leg sheets joined to both side edges of the absorbent structure and extending in a longitudinal direction. Each of the elasticized leg sheets having a non-elasticized region adjacent to the absorbent structure and an elasticized region adjacent to the non-elasticized region so that the non-elasticized region rises along the associated side edge of the absorbent structure to the associated leg-opening and the elasticized region extends outward in a transverse direction of the wearing article so as to form the associated leg-opening. | 2016-01-21 |
20160015575 | DISPOSABLE PULL-ON DIAPER - The present invention aims to provide a disposable pull-on diaper improved so that the diaper may be conveniently put on the wearer's body. | 2016-01-21 |
20160015576 | EXTRUSION BONDED LAMINATES FOR ABSORBENT ARTICLES - An absorbent article of the present invention may comprise a topsheet, an outer cover, and an absorbent core disposed therebetween. The outer cover may comprise an extrusion bonded laminate. The EBL may comprise a multi-layer coextruded elastomeric film and a nonwoven. The film may comprise a core layer, a first outer layer, and a second outer layer, wherein the core layer is between the first and second outer layers. The nonwoven may comprise fibers and/or filaments. The first outer layer may be non-adhesively joined to the nonwoven via extrusion coating. Further, the outer cover may be elastic to at least about 50% engineering strain. The nonwoven may have high chemical affinity for the first outer layer. The first outer layer may have a low chemical affinity for the core layer; and the multi-layer coextruded elastomeric film may have a basis weight no greater than about 40 gsm. | 2016-01-21 |
20160015577 | DISPOSABLE ABSORBENT PRODUCTS IN A STACKED ARRANGEMENT - Disposable absorbent products are stacked along a stacking axis. Each of a first plurality of folded disposable absorbent products is folded into at least two panels so as to define first and second ends and front and back oppositely-facing exterior faces of each of the first plurality of folded products, with the respective front faces of the first plurality of folded products facing a common, first direction. At least one folded disposable absorbent product is folded substantially in the same manner as the first plurality of folded products to thereby define first and second ends and front and back oppositely-facing exterior faces of that at least one folded product, with the front face of that at least one folded product facing a second direction opposite from the first direction. | 2016-01-21 |
20160015578 | DIAPER - A diaper has a diaper body, two straps and at least one strap hook-and-loop fastener. The diaper has an absorbent portion, a front covering portion connected with the absorbent portion, at least one body hook-and-loop fastener mounted on the front covering portion, and a rear covering portion connected with the absorbent portion. The straps are elongated and are respectively connected with two sides of the rear covering portion. The at least one body hook-and-loop fastener is selectively attached to the outer side of one of the straps. The at least one strap hook-and-loop fastener is mounted on one of the inner side and the outer side of one of the straps, and the at least one strap hook-and-loop fastener is selectively attached to the other strap. Therefore, the diaper can be suitable for different users of different waist sizes. | 2016-01-21 |
20160015579 | ABSORBENT ARTICLE - The absorbent article provides a signal viewable from the top surface of the absorbent article. This signal includes a colored portion having a first shade and a second shade. | 2016-01-21 |
20160015580 | LEVER-OPERATED WHEELCHAIR - In one embodiment, a wheelchair drive mechanism adapted to mount to a wheelchair includes a drive lever adapted to be rotated forward and rearward by a user of the wheelchair, a clutch mechanism associated with the drive lever, wherein actuation of the clutch mechanism causes the drive lever to be coupled to a wheel of the wheelchair such that they rotate together, and a clutch actuation device provided on the drive lever that is operable by the wheelchair user to actuate the clutch mechanism. | 2016-01-21 |
20160015581 | METHOD AND APPARATUS FOR AUTOMATED POSITIONING OF USER SUPPORT SURFACES IN POWER DRIVEN WHEELCHAIR - By programming position parameters corresponding to user support surfaces of a power driven wheelchair, movement of the user support surfaces is automated. The user support surfaces can be positioned individually, as part of a sequence or as part of a series of sequences. Accordingly, with little effort, a user can position the user support surfaces of the wheelchair to a predefined position. | 2016-01-21 |
20160015582 | ADJUSTING DEVICE FOR A HEIGHT-ADJUSTABLE PLATFORM AND METHOD FOR ADJUSTING THE HEIGHT OF THE PLATFORM - The height of a platform relative to a support surface is adjustable by rotating a drive shaft to actuate a first height-adjusting device and a second height-adjusting device, thereby changing the height of the respective ends of the first and second height-adjusting devices relative to the support surface. The drive shaft is selectively drivable by either a drive motor or a manually-operable drive. | 2016-01-21 |
20160015583 | ADJUSTABLE SUPPORT DEVICE ADJUSTABLE BY AN ELECTRIC MOTOR - An adjustable support device adjustable by an electric motor, for supporting padding of seating or reclining furniture has an outer frame and a base body having at least two support parts. The two support parts are adjustable relative to one another. An adjustment element, which is in drive connection with a drive unit, is associated with at least one of the adjustable support parts. The adjustment element is a pivot lever which is pivotable under the traction effect of a pull cable of a Bowden cable, and the pivot lever is pivotably connected to the associated support part, and is supported on a support situated on the outer frame. Or the pivot lever is pivotably connected to the outer frame, and with its free end forms a support for the support part to be adjusted. | 2016-01-21 |
20160015584 | GAIT BELT - A support belt assists caretaker in moving an ambulatory-impaired person. A strap has a plurality of attachment fixtures such as grommets that are longitudinally spaced and has a buckle for engaging the strap around a torso of an individual. The connector is engageable between a selected two of the attachment fixtures to draw one portion of the strap to closely encircle the ambulatory-impaired person and to form another portion of the strap into a grasping loop. A second support belt can be attached to the strap by two or more belt connector in order to double the portion of the torso encircled or to support buttocks or thigh of the ambulatory-impaired person. | 2016-01-21 |
20160015585 | Infant Warming Device with Rotating Patient Support Power, Signal Control Data and Communications - An electrical connection system that can feed power, signal, data, and communication lines into a rotating or static patient support system in an infant warming device. | 2016-01-21 |
20160015586 | Infant Care Transport Device with Shock and Vibration System - A shock and vibration system for an infant care transport system with an enclosed infant care device. The shock and vibration system utilizes multiple damping systems that create a floating patient support system that allows the infant care device to move in the various axes of motion instead of being rigidly mounted to the frame or sub-frame, or any substructure. | 2016-01-21 |
20160015587 | Warming Therapy Device with Integrated Moveable Video and Still Camera - An integrated and movable video and/or still camera is integrated into a warming therapy device to allow caregivers to point the camera in an area of interest in which they are interested in recording or displaying the patient located on a support surface. The system may include an audio recording device. | 2016-01-21 |
20160015588 | HEAD POSITIONING DEVICE, MEDICAL SYSTEM, MEDICAL INSTRUMENT POSITIONING DEVICE, AND HOLDING SHELL - Provided is an inexpensive device capable of accurately positioning a medical instrument relative to the head of a user. A head positioning device ( | 2016-01-21 |
20160015589 | SUPPORTING FRAME AND MOTION ASSISTANCE APPARATUS INCLUDING THE SAME - A supporting frame and a motion assistance apparatus including the same may be provided. In particular, the supporting frame including a first frame including a hinge connecting portion, a second frame configured to slidingly move with respect to the first frame, and an assistance force sensing portion on at least one of the first frame and the second frame may be provided. | 2016-01-21 |
20160015590 | HAND EXOSKELETON DEVICE - In a hand exoskeleton device, according to a three-layered sliding spring mechanism, the motion of the device is changed by a single drive mechanism to transmit power to the metacarpophalangeal, proximal and distal interphalangeal joints of a human finger, thereby enabling support of the daily activity motions of the finger. According to the hand exoskeleton device, when compared with a conventional device, there can be realized a device which is small in size and weight and is capable of supporting the gripping motions of the human finger. The hand exoskeleton device is characterized in that the three joints of the finger can be bent and extended by the single drive mechanism and it can transmit large drive power. Further, the device body is flexible, thereby enabling safe movement. | 2016-01-21 |
20160015591 | OVERHEAD STANDING AND AMBULATION ASSISTIVE EXERCISE DEVICE - An exercise apparatus adapted to hang from an overhead structure used for providing walking and ambulation assistance to users in aid of exercise and physical rehabilitation. The device has a pulley assembly adapted for anchoring directly to an overhead structure or indirectly by a track secured thereto, and includes a hoist line permitting manual force to be used to raise and lower a sling assembly that is secured in the underarms of the user for lifting. | 2016-01-21 |
20160015592 | Micromechanical Force Devices for Wound Healing Acceleration - An apparatus provides micromechanical forces on a wound bed to accelerate healing of a wound. The apparatus includes a pressure chamber having a substantially airtight plunger and an inlet fluidly connected to a first end of a conduit. A constant force spring is operatively connected to apply a constant force to the plunger. A suction cup is in fluid communication with a second end of the conduit. | 2016-01-21 |
20160015593 | Compression Device Having Cooling Capability - A compression device has improved cooling capability. The device includes a wicking layer adapted to move moisture. A portion of the wicking layer is exposed from under bladder material defining a bladder. In use, the wicking layer wicks moisture from the patient's limb and the wicked moisture is able to evaporate through the device at the portion of the wicking layer that is exposed. | 2016-01-21 |
20160015595 | MASSAGE DEVICE - The invention relates to a massage device comprising a device housing, with electromechanical means arranged in the housing for generating mechanical vibrations, along with electronic means arranged in the housing for activating the means for generating mechanical vibrations, and with a power source, connected to the means for generating mechanical vibrations and the electromechanical means, wherein the means for generating mechanical vibrations comprise at least one coil element and at least one ferromagnetic core arranged parallel or coaxial with the coil element and movably guided parallel to a cylinder axis, characterized in that the core has a mass m1, the mass ratio m1:m2 of which to the total mass m2 of the massage device is in the range from 1:100 to 1:3. | 2016-01-21 |
20160015597 | Portable Infrared Sauna - Disclosed in this document are devices and methods for creating temporary enclosures made substantially of wood or cellulose based materials that are unadulterated or not processed with foreign chemicals, wherein the enclosure is capable of supporting a bulb assembly to form a temporary sauna. One embodiment of the temporary enclosure is a near infrared sauna system that supports a near infrared heat source and maintains adequate temperature. The infrared sauna system exposes a person sitting inside the enclosure to the comfort and benefits of a near infrared sauna. In this document, innovative elements combine to create a temporary building structure that overcomes the need for nails, screws and other external tools previously necessary when using unadulterated materials, such as poplar wood and bamboo. | 2016-01-21 |
20160015598 | Biological Sample Containment System and Label - A biological sample containment system that includes a biological specimen collection container for collecting a biological sample and a label for the container is disclosed. In one embodiment, the label includes a first or front side and a second or rear side having a readable information portion. The label is affixable to the container by the second side and with the label affixed to the container, the readable information portion on the second side is readable through a portion of the container. By including readable information on the second or rear side of the label, the amount of readable information that can be included on the label is increased by using the previously unused rear side of the label. | 2016-01-21 |
20160015599 | RECEPTION, DRAINING AND TRANSFER OF A HIGH QUANTITY OF BIOPHARMACEUTICAL FLUID UNDER PRESSURE WITH A VIEW TO SUBSEQUENT TREATMENT - Device for receiving and draining a high quantity of biopharmaceutical fluid under pressure includes an inner bag, having an inner container for receiving the fluid and provided with a filling port, a drain port, a filling tube having a filling inlet for connection to a filling line, a drain tube having a drain outlet for connection to a drain line, an outer container in which the bag is placed, a compression chamber between the outer container and the bag, an injection port for injecting pressurized draining gas into the chamber, sealed bushings passing through the container via the filling and drain tubes, the deformation capacities of the bag and container being such that, when the draining gas is injected into the chamber, the bag is compressed and the biopharmaceutical fluid is emptied. The outer container includes a receptacle forming the outer chamber, the tubes passing therethrough via permanently fixed connections. | 2016-01-21 |
20160015600 | COATED PACKAGING - A vessel has an interior surface facing a lumen. The interior surface includes a tie coating or layer, a barrier coating or layer, and a pH protective coating or layer. The tie coating or layer can comprise SiO | 2016-01-21 |
20160015601 | NEEDLE-LESS VIAL ASSEMBLY FOR USE WITH NEEDLE-FREE SYSTEM - A needle-less vial assembly that includes a substance transfer assembly configured to telescopically engage with a vial neck of a vial. A first portion of the substance transfer assembly is configured to sealingly engage with an interior wall of the vial neck, where the first portion includes a first inlet configured to receive a substance from the vial. A second portion of the substance transfer assembly is configured to matingly engage with a syringe, and includes an outlet configured to dispense the substance to the syringe. A channel is defined through the first portion and the second portion, thereby enabling fluid communication of the substance from the vial to the syringe via the first inlet and the outlet. | 2016-01-21 |
20160015602 | Method and Apparatus for Medication Storage and Delivery - An intelligent pill box device comprising: a base and a display panel. The base includes a plurality of cylindrical shaped receptacles for storing medication bottles wherein each receptacle includes a radio frequency identification reader, a faraday cage, and a load cell at the bottom of the receptacle to measure the weight of the contents of the receptacle. | 2016-01-21 |
20160015603 | Infant Feeding System - A method of feeding breast milk to an infant includes providing a spout pouch having a spout, providing a plurality of adapters configured to couple to the spout pouch, coupling the spout of the spout pouch to a first adapter, coupling the first adapter to a breast pump, operating the breast pump to express breast milk into the spout pouch, so that the spout pouch collects the expressed breast milk, coupling a second adapter to the spout of the spout pouch, and coupling the second adapter to a nipple, so that expressed breast milk flows from the spout pouch to the nipple. Other systems, methods, and components are also provided. | 2016-01-21 |
20160015604 | TWO-COMPONENT ADHESIVE FOR BONDING ARTIFICIAL TEETH TO A DENTURE BASE - A mixture containing at least one first component A and at least one second component B, characterized in that said at least one first component A comprises a methyl methacrylate, a copolymer of methyl methacrylate dissolved in excess methyl methacrylate, optionally comprising, additionally dissolved therein, at least one polyfunctional (meth)acrylate, especially ethylene glycol dimethacrylate, butanediol dimethacrylate, hexanediol dimethacrylate, triethylene glycol dimethacrylate (TEGDMA), tetraethylene glycol dimethacrylate, diurethane dimeth-acrylate, bis(hydroxymethacryloyloxypropoxy)phenylpropane (bis-GMA), polyethylene glycol dimethacrylate, trimethylolpropane trimethacrylate, ditrimethylol-propane tetraacrylate;and a peroxide-based free-radical initiator, wherein said copolymer of methyl methacrylate is present in an amount of 30-50 parts by weight dissolved in a solution of 65-85 parts by weight of monomeric methyl methacrylate and 3-15 parts by weight of the polyfunctional (meth)acrylate, especially the triethylene glycol dimethacrylate (TEGDMA), mixed with a solution of 0.5 to 3 parts by weight of said peroxide-based free-radical initiator, especially dibenzoyl peroxide, in 70-90 parts by weight of monomeric methyl methacrylate, and said at least one second component B comprises methyl methacrylate and a tertiary amine. | 2016-01-21 |
20160015605 | DENTAL GYPSUM POWDER - The problem to be solved is to provide a dental gypsum powder capable of suppressing mixing of bubbles in a kneaded object while including a resin component. A dental gypsum powder includes 0.5 to 4 wt. % of a solid component included in acrylic polymer dispersion; and 0.001 to 0.2 wt. % of cyclic siloxane including 3 to 10 SiO(CH | 2016-01-21 |
20160015606 | Sunscreen Compositions Comprising Uniform, Rigid, Spherical, Nanoporous Calcium Phosphate Particles and Methods of Making and Using the Same - Aspects of the invention include sunscreen formulations that include uniform, rigid, spherical nanoporous calcium phosphate particles. Also provided are methods of making the sunscreen formulations. The sunscreen formulations find use in sunblocking applications. | 2016-01-21 |
20160015607 | Shaving Oil Wipe - A shaving oil wipe made from combining a wipe or wipe-type product with natural fats or oils for shaving. The shaving oil wipe includes a package unit and at least one shaving oil wipe received in the package unit. The shaving oil wipe includes a fibrous carrier and a shaving oil composed of oils from either natural or synthetic sources. The shaving oil is disposed on the surface of the fibrous carrier or impregnated on the fibrous carrier. When the shaving oil of the shaving oil wipe is applied on a user's skin, a layer of oil is produced on the skin to provide good lubrication for shaving. Convenience of usage, good portability, and efficient application of shaving oil to skin are advantages. | 2016-01-21 |
20160015608 | COMPOSITION FOR HAIR FRIZZ REDUCTION - An aqueous hair leave-on composition directed to an aqueous hair leave-on composition for hair frizz reduction comprising from about 0.15% to about 12.0% of a moisture control material or mixture of moisture control materials wherein the moisture control material is selected from one or more of the following class:
| 2016-01-21 |
20160015609 | NOVEL WATER-IN-OIL EMULSIONS WITH A HIGH CONTENT OF AQUEOUS PHASE AND OF LIQUID CONSISTENCY, WHICH ARE STABLE ON STORAGE - An oil-in-water emulsion including, by 100% of its mass: 60% to 98% of aqueous phase (A | 2016-01-21 |
20160015610 | COLOUR CHANGING COMPOSITION IN EMULSION FORM COMPRISING AN EMULSIFYING HYDROPHILIC GELIFYING AGENT - The instant invention relates to a colour changing composition in the form of an emulsion comprising, at least: a) microcapsules containing releasable colorant(s), said microcapsules comprising: —a core comprising one organic material, —at least one layered coating surrounding said core, the layered coating comprising at least one polymer, at least one colorant, and advantageously at least one lipid-based material, b) at least one emulsifying hydrophilic gelifying agent chosen from 2-acryl-amido-2-methylpropanesulphonic acid copolymers, and c) at least one C6-C10 aromatic ether of C2-C9 polyol. | 2016-01-21 |
20160015611 | COLOUR CHANGING COMPOSITION IN EMULSION FORM COMPRISING A PARTIALLY NEUTRALIZED, CROSSLINKED ACRYLIC HOMOPOLYMER OR COPOLYMER - The instant invention relates to a colour changing composition in the form of an emulsion comprising, at least: a) microcapsules containing releasable colorant(s), said microcapsules comprising: —a core comprising one organic material, —at least one layered coating surrounding said core, the layered coating comprising at least one polymer, at least one colorant, and advantageously at least one lipid-based material, b) at least partially neutralized, crosslinked acrylic homopolymers or copolymers preferably in a non-particulate form. | 2016-01-21 |
20160015612 | Preservative System for Cosmetic Formulations-Compositions and Methods Thereof - The present invention relates to preservation of cosmetic formulations. More specifically, the present invention relates to a preservative composition for cosmetic formulations comprising thymol, monolaurin and magnolol obtained from supercritical fluid extracts of | 2016-01-21 |
20160015613 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND FRAGRANCES - Disclosed are active ingredient combinations of alkylamidothiazoles and one or more cosmetically or dermatologically relevant fragrances. | 2016-01-21 |
20160015614 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND UV-FILTER SUBSTANCES - Disclosed are active ingredient combinations of alkylamidothiazoles and one or more cosmetically or dermatologically acceptable UV-filter substances. | 2016-01-21 |
20160015615 | COMBINATIONS OF ALKYLAMIDOTHIAZOLES AND PRESERVATIVES - Disclosed are active ingredient combinations of alkylamidothiazoles and one or more cosmetically or dermatologically acceptable preservatives. | 2016-01-21 |
20160015616 | PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS - A personal care composition is provided having a highly volatile fragrance which incorporates alpha pinene, beta pinene, hexyl acetate, limonene, (+)-citronellal, dihydromyrcenol, alpha citronellol, beta citronellol, genaniol, lilial or combinations thereof in conjunction with tricyclodecane amide. The tricyclodecane amide functions to prevent fast volatilization of the highly volatile fragrance components when the personal care composition is applied to skin or hair of the human body. | 2016-01-21 |
20160015617 | Compositions and Methods for Reducing Skin Pigmentation - The present invention provides compositions and methods for reducing skin pigmentation. The invention comprises inhibitors of sialyltransferase, inhibitors of oligosaccharide formation or oligosaccharide activity, and methods of using such inhibitors. In certain embodiments, the invention comprises inhibiting the formation and/or activity of Neu5Ac(α2,6)Gal/GalNAc-containing oligosaccharides. | 2016-01-21 |
20160015618 | SKIN COLLAGEN PRODUCTION-PROMOTING AGENT - A problem of the present invention is to provide a skin collagen production-promoting agent without safety problems. Another problem of the present invention is to provide a skin collagen production-promoting food or drink product and a skin collagen production-promoting cosmetic product containing such a substance. TGF-β and/or a TGF-β degradation product, which is acquired by degrading TGF-β with a protease such as pepsin, pancreatin, etc., are used as a skin collagen production-promoting agent or the active ingredient of a skin collagen production-promoting food or drink product and a skin collagen production-promoting cosmetic product. The aforementioned TGF-β and/or TGF-β degradation product have an effect of increasing the collagen content of the skin. | 2016-01-21 |
20160015619 | TRANSPARENT SOL, GEL COMPOSITION CONTAINING HIGH CONCENTRATIONS OF VITAMIN C AND VITAMIN C DERIVATIVE - The present invention relates to a transparent sol, gel composition containing high concentrations of vitamin C and vitamin C derivative. More specifically, disclosed is a technical field associated with a vitamin C composition, which is usable as an essence, a mask pack, a hydrogel mask, or the like, by making a composition containing a high concentration of vitamin C or vitamin C derivative, a polyalcohol, an acid mucopolysaccharide, and a hydrophilic solvent, into a sol or gel so as to stabilize the high concentration of vitamin C or vitamin C derivative in an aqueous solution. In addition, the present invention has a dosage form of a high-viscosity sol or gel phase since the vitamin C or the vitamin C derivative is dissolved in the aqueous solution, and therefore, provided is a high-viscosity composition having effects of suppressing carbon dioxide which may be generated when vitamin C is unstable, not easily deteriorating by minimizing the contact with air due to little movement when being carried or stored, being convenient to use, having external beauty due to a transparent appearance, and being stable. | 2016-01-21 |
20160015620 | USE OF CHITOSANS TO INCREASE NAIL GROWTH RATE - The present invention is directed to the use of chitosan, a chitosan derivative or a physiologically acceptable salt thereof, to increase nail growth rate. The invention is further directed to the use of chitosans to accelerate nail growth rate during treatment of nail illnesses, nail dystrophy or other nail conditions, in order to shorten considerably the specific treatments of said nail illnesses, nail dystrophy or other nail conditions. | 2016-01-21 |
20160015621 | Sunscreen Formulations - Sunscreen formulations with improved thickening and waterproofmg properties include a polymer prepared from monomers including: styrene, a (meth)acrylic acid-containing monomer and an ester of acrylic acid or methacrylic acid or an acryl amide monomer, and an acrylic acid homopolymer thickener. | 2016-01-21 |
20160015622 | Surfactant Activated Microgel Polymers And Methods To Mitigate The Loss Of Silicone Deposition From Keratinous Substrates - A conditioning and cleansing composition comprising at least one detersive surfactant, a silicone conditioning agent and a nonionic, amphiphilic polymer that mitigates the loss silicone deposition on keratinous substrates is disclosed. The nonionic, amphiphilic polymer is prepared by polymerizing a monomer composition comprising: a) from about 55 to about 95 wt. % of at least one vinyl amide monomer (based on the weight of the total monomers present); b) from about 5 to about 45 wt. % of at least one vinyl ester of an aliphatic carboxylic acid containing an acyl moiety having 2 to 22 carbon atoms (based on the weight of the total monomers present); c) from about 0 to about 1 wt. % of at least one polyunsaturated crosslinking monomer containing at least two polymerizable ethylenically unsaturated moieties (based on the total dry weight of the polymer); d) from about 0 to about 10 wt. % of at least one C1-C22 alkyl (meth)acrylate (based on the weight of the total monomers present); e) from about 0 to about 10 wt. % of an alkoxylated associative monomer (based on the weight of the total monomers present); f) from about 0 to about 10 wt. % of an alkoxylated semi-hydrophobic monomer (based on the weight of the total monomers present); and g) from about 0 to about 5 wt. % of at least one vinyl ester of an aliphatic carboxylic acid containing an acyl moiety having 2 to 22 carbon atoms (based on the weight of the total monomers present) other than vinyl acetate. | 2016-01-21 |
20160015623 | ORAL CARE COMPOSITIONS - Described herein are oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with particular co-polymers as additional excipients; including some embodiments which further comprise a calcium abrasive. | 2016-01-21 |
20160015624 | Sunscreen Compositions - Compositions comprising an organic sunscreen in combination with (i) nylon particles, (ii) silica particles, and (iii) barium sulfate particles provide an improvement in SPF as compared to an otherwise identical composition lacking any one of the three ingredients (i)-(iii). The compositions advantageously provide high diffuse transmittance, giving a natural look to the skin. | 2016-01-21 |
20160015625 | Method of Applying Organic Virgin Coconut Oil to Eyelashes and Eyebrows - A method for applying undiluted 100% Organic Virgin Coconut Oil to the eyelashes and/or eyebrows of a user via a brush is described. The brush employed is preferably equipped with a series of off-set bristles configured to be soft on the lashes, yet firm enough to adequately apply the coconut oil to the lashes and distribute the coconut oil evenly across all lashes. Via this method, the organic virgin coconut oil is applied to the lashes such to ensure that each lash or brow is effectively moisturized in order to enhance the life and aesthetic quality of the eye lashes and/or eyebrows. | 2016-01-21 |
20160015626 | WHOLE STABLIZED OLIVE MILL PROCESS WATER, PRODUCTION THEREOF AND USES THEREOF - The present invention relates to processes for producing treated olive mill process water (OMPW). In some exemplary embodiments, the treated OMPW is used in the preparation/production of body care products. | 2016-01-21 |
20160015627 | LACTOBACILLUS PLANTARUM NCC 2936 PREPARATIONS AND ORAL HEALTH - The present invention relates generally to compositions with a health benefit. In particular, the invention relates to bacterial preparations of | 2016-01-21 |
20160015628 | HETEROCYCLIC COMPOUNDS AND THEIR USES - Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use. | 2016-01-21 |
20160015629 | PHARMACEUTICAL COMPOSITION FOR PREPARING DRUG DELIVERY NANO/MICRO BUBBLES - The pharmaceutical composition includes a drug layer comprising an active ingredient, a surfactant, an acidic component and an effervescent ingredient. The active ingredient comprises a nucleic acid, a peptide or a protein. The acidic component and effervescent ingredient of the drug layer are dissolved in the water to react for generating carbon dioxide and bubbles thereof. The surfactants surround the carbon dioxide gas core and form a double-layer structure having an inner layer and outer layer. The active ingredient is embedded in a gap formed between the inner layer and the outer layer of the double-layer structure. | 2016-01-21 |
20160015630 | SPRAYABLE OXYGENATED SALINE COMPOSITION AND METHOD FOR TREATING NASAL CONGESTION, ALLERGY, DRYNESS, EYE IRRITATION, THROAT IRRITATION, WOUNDS, AND SKIN AS APPLIED TO HUMAN TISSUES - An oxygenated saline composition is provided comprising stabilized oxygen, sodium chloride (aqueous saline solution), and optionally one or more homeopathic components. The stabilized oxygen can include quad-atomic oxygen. Also provided is a method for treating, reducing or preventing nasal and/or sinus congestion, allergy, dryness, throat irritation, skin irritation, wounds, or eye irritation comprising administering to an individual in need thereof an effective amount of an oxygenated saline composition comprising stabilized oxygen, aqueous saline solution, and optionally one or more homeopathic components, wherein the composition is administered by intranasal spraying, throat spray, skin spray, sublingually, or by eye drops. | 2016-01-21 |
20160015631 | OCULAR DRUG DELIVERY SYSTEM - An ocular drug delivery system can include a composition in which a formulation including recombinant human growth hormone (rHGH) is contained in a polymer matrix. The composition is configured for placement in or on the eye of a subject, and provides controlled release of an amount of the rHGH to the eye effective to promote healing of a conjunctival, sclera and or corneal wound. | 2016-01-21 |
20160015632 | SUSPENSION COMPOSITIONS OF CYCLOSPORIN A FOR SUBCONJUNCTIVAL AND PERIOCULAR INJECTION - The present disclosure relates to suspension formulations and systems for the treatment of ocular conditions. The suspension formulations can include cyclosporin A and in some embodiments, Form 1 or Form 2 cyclosporin A. A delivery system can be provided that includes two parts, a first part containing particles of cyclosporin and a second part containing other components that can be combined with the first part to make a suspension formulation. The suspension can be injected into the subconjunctival or other periocular space to treat ocular conditions, such as dry eye disease. | 2016-01-21 |
20160015633 | XYLITOL CONTAINING COMESTIBLE PRODUCT - The present invention relates to a process for preparing a comestible product comprising xylitol said method comprising: (a) subjecting a composition comprising xylitol in an amount ranging from about 60% to about 100% by weight to extrusion treatment inside an extrusion apparatus under conditions sufficient to form and maintain the xylitol in a slurry and (b) then shaping the extruded slurry and cooling the product to form a solid. The present invention additionally is directed to a product produced therefrom. | 2016-01-21 |
20160015634 | AQUEOUS SUSPENSIONS OF CICLESONIDE FOR NEBULISATION - This invention relates to a method for the preparation of sterile aqueous suspensions of ciclesonide by sterilization with moist heat. The invention further relates to pharmaceutical compositions in particular to sterile aqueous suspensions of ciclesonide for administration by nebulization in the prophylaxis and/or treatment of respiratory diseases. | 2016-01-21 |
20160015635 | NANO / MICRO BUBBLES FOR DRUG DELIVERY - The present invention provides a nano/micro bubble system for drug delivery comprising a gas core, a plurality of surfactants and an active ingredient. The surfactants surround the gas core and form a double-layer structure having an inner layer and outer layer. The active ingredient is embedded in a gap formed between the inner layer and the outer layer of the double-layer structure and comprises a nucleic acid, a peptide or a protein. | 2016-01-21 |
20160015636 | NOVEL LOW DENSITY LIPOPROTEIN NANOCARRIERS FOR TARGETED DELIVERY OF OMEGA-3 POLYUNSATURATED FATTY ACIDS TO CANCER - The presently disclosed LDL nanocarrier is an effective and appropriate transporter for DHA in biological systems. The LDL-DHA nanoparticle was shown to be preferentially cytotoxic to malignant liver cells. LDL-DHA nanoparticles show great promise as an anti-cancer agent. | 2016-01-21 |
20160015637 | ANTI-ITCHING POWDER - The present invention is anti-itching powder that blocks transmission to stratum corneum and invasion up to epidermal cells by emulsion as a result of further concentration on skin stratum corneum. The emulsion is produced by mixing sweat continuously secreted during rest and sebum. The emulsion becomes a cell disorder composition. Specifically, the anti-itching powder as a fine powder contains main ingredients of aluminum chloride or alum and cyclodextrin. A fine powder as a base is dispersed into and combined with the fine powder. The application of the fine powder over the skin prevents sudden itch without blocking emission and transpiration of moisture in the sweat from the skin stratum corneum. | 2016-01-21 |
20160015638 | STABLE GLUCOKINASE ACTIVATOR COMPOSITIONS - The invention relates to stable pharmaceutical compositions comprising a glucokinase (GK) activator suitable for oral administration. The invention also relates to methods of making and using such pharmaceutical compositions. | 2016-01-21 |
20160015639 | Cyclodextrin Compositions Encapsulating a Selective ATP Inhibitor and Uses Thereof - The invention provides compositions comprising cyclodextrins encapsulating a selective ATP inhibitor, as well as uses thereof. | 2016-01-21 |
20160015640 | CRYSTALLINE MICROSPHERES AND THE PROCESS OF MANUFACTURING THE SAME - Microspheres comprising a core material, wherein the microspheres have a circularity greater than 0.95 and an aspect ratio greater than 0.95, and methods of manufacturing the same. The microspheres may be useful in the manufacture of sustained and modified release active pharmaceutical ingredient (API) microspheres, as a free flowing excipient for mini-tablets and in the manufacture of API dispersions. | 2016-01-21 |
20160015641 | Levothyroxine Formulations - A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 0.1 to 7 milligrams mannitol. | 2016-01-21 |
20160015643 | FORMULATIONS OF ORGANIC COMPOUNDS - The present invention relates to solid pharmaceutical compositions comprising the phosphatidylinositol 3-kinase inhibitor compound 4-(trifluoromethyl)-5-(2,6-dimorpholinopyrimidin-4-yl)pyridin-2-amine or a pharmaceutically acceptable salt thereof, sodium stearyl fumarate, and optionally at least one additional pharmaceutically acceptable carrier. The present invention also relates to the processes for their preparation and to their use as medicaments for the treatment of cancer. | 2016-01-21 |
20160015644 | GASTRO-RETENTIVE SUSTAINED-RELEASE ORAL DOSAGE FORM OF A BILE ACID SEQUESTRANT - Disclosed herein are novel compositions and methods for controlling the release of bile acid sequestrant to the stomach in order to treat or prevent upper GI tract disorders or disorders of the throat. The methods generally include administering to a patient in need thereof a therapeutically effective amount of a pharmaceutical composition comprising at least one bile acid sequestrant dispersed in a polymeric matrix. The bite acid sequestrant composition may be administered alone or in combination with at least one proton pump inhibitor, and optionally one or more agents chosen from antacids, histamine H | 2016-01-21 |
20160015645 | Extended Release Pharmaceutical Composition Of Entacapone Or Salts Thereof - There is provided an extended release pharmaceutical composition comprising from about 200 mg to about 1000 mg of entacapone or salts thereof, optionally with other pharmaceutically acceptable excipients. The invention also provides an extended release pharmaceutical composition comprising triple combination of from about 30 mg to about 300 mg of levodopa, 10 mg to about 100 mg of carbidopa and 200 mg to about 1000 mg of entacapone or salts thereof, optionally with other pharmaceutically acceptable excipients. The invention also relates to process of preparation of such compositions. | 2016-01-21 |
20160015646 | Oral delivery system for sorafenib tosylate - The present invention relates to a gastroretentive tablet for treating unresectable hepatocellular carcinoma, comprising an enteric polymer, a nanoparticle and an excipient, wherein the nanoparticle comprises an oral multikinase inhibitor, wherein the oral multikinase inhibitor is coated with an amino methacrylate copolymer, wherein the oral multikinase inhibitor is sorafenib, and wherein the enteric polymer is methacrylic acid copolymer. The excipient is selected from a group consisting of a retarding agent, a binder, a filler, a diluent, a disintegrant, a lubricant, a colorant, a solubilizing agent, or a mixture thereof. | 2016-01-21 |
20160015647 | BISMUTH LIQUID FILLED HARD CAPSULES - The present disclosure relates to a new, stable, oil based liquid suspension filled hard capsule dosage form for bismuth salts such as bismuth subsalicylate, a process for its manufacture, methods to deliver bismuth salts to humans or animals via stable hard capsules, and improved methods of treating gastrointestinal disorders with such dosage forms. | 2016-01-21 |
20160015648 | ENHANCED DRUG DELIVERY PILL - An ingestible pill includes a coating configured to dissolve in a small intestine; a core, which includes a medication-delivery element, which (a) has a compressed shape when disposed within the coating, and (b) is configured to assume, after the coating dissolves, an expanded shape; a medication; and a mucoadhesive. When unconstrained in the expanded shape, the medication-delivery element (a) is shaped so as to define first and second surfaces on opposite sides of the medication-delivery element, which have respective outer perimeters, which surround respective spaces of the respective surfaces, which spaces have respective greatest dimensions equal to between 2 and 10 cm, and each of which spaces has an area equal to at least 50% of the square of the greatest dimension; and (b) has an average thickness between the first and the second surfaces of less than 6 mm. Each of the medication and the mucoadhesive at least partially coats the first surface. | 2016-01-21 |
20160015649 | PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMINISTRATION OF HYDROPHOBIC DRUGS - Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs are provided. The pharmaceutical compositions include a therapeutically effective amount of a hydrophobic drug, preferably a steroid; a solubilizer, and a surfactant. The synergistic effect between the hydrophobic drug and the solubilizer results in a pharmaceutical formulation with improved dispersion of both the active agent and the solubilizer. As a result of the improved dispersion, the pharmaceutical composition has improved bioavailability upon administration. Methods of improving the bioavailability of hydrophobic drugs administered to a patient are also provided. | 2016-01-21 |
20160015650 | Immediate Release Abuse Deterrent Liquid Fill Dosage Form - The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form. | 2016-01-21 |
20160015651 | HARD CAPSULE FORMULATION - A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule. | 2016-01-21 |
20160015652 | HOLLOW NANOPARTICLES WITH HYBRID DOUBLE LAYERS - The present invention discloses the morphology of hollow, double-shelled submicrometer particles generated through a rapid aerosol-based process. The inner shell is an essentially hydrophobic carbon layer of nanoscale dimension (5-20 nm), and the outer shell is a hydrophilic silica layer of approximately 5-40 nm, with the shell thickness being a function of the particle size. The particles are synthesized by exploiting concepts of salt bridging to lock in a surfactant (CTAB) and carbon precursors together with iron species in the interior of a droplet. This deliberate negation of surfactant templating allows a silica shell to form extremely rapidly, sealing in the organic species in the particle interior. Subsequent pyrolysis results in a buildup of internal pressure, forcing carbonaceous species against the silica wall to form an inner shell of carbon. The incorporation of magnetic iron oxide into the shells opens up applications in external stimuli-responsive nanomaterials. | 2016-01-21 |
20160015653 | FILMS AND DRUG DELIVERY SYSTEMS MADE THEREFROM - The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film. The invention further relates to edible multi-layer films that dissolve in water. In particular, the edible multi-layer films have a first water-soluble film layer and one or more additional water-soluble film layers in at least partial face-to-face engagement with the first film layer. | 2016-01-21 |
20160015654 | ADHESIVE COMPOSITION FOR MEDICAL USE, PATCH FOR MEDICAL USE, AND METHOD FOR PRODUCING THE COMPOSITION - An adhesive composition for medical use of the present invention includes an acrylic copolymer, a medicament having a carboxyl group, and a base, the acrylic copolymer is prepared by copolymerization of a monomer mixture containing 0.1 to 2 mass % of an ethylenically unsaturated carboxylic acid monomer as a monomer A, 58 to 99.9 mass % of an alkyl(meth)acrylate ester having an alkyl group of 4 to 12 carbon atoms as a monomer B, 30 mass % or less of an alkyl(meth)acrylate ester having 1 to 3 carbon atoms as a monomer C, and 30 mass % or less of a monomer having an ethylenically unsaturated group other than those of the monomers A to C (the total of monomers A to D is taken as 100 mass %) as a monomer D, and the content of sulfuric acid in the acrylic copolymer is 700 ppm by mass or less. | 2016-01-21 |
20160015655 | TRANSDERMAL ESTROGEN DEVICE AND DELIVERY - Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described. | 2016-01-21 |
20160015656 | COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE - The present invention relates to a pharmaceutical composition and a method for regenerating normal tissue from fibrotic tissue, the pharmaceutical composition and the method employing a collagen-reducing substance. In accordance with the present invention, normal tissue can be therapeutically regenerated from fibrotic tissue. | 2016-01-21 |