02nd week of 2021 patent applcation highlights part 11 |
Patent application number | Title | Published |
20210008269 | METHOD FOR TREATING DRUG INTOXICATION - Methods and devices are disclosed for the treatment of a subject suffering from drug intoxication by cleansing a contaminated sample from the subject with adsorption media. The adsorption media composition is selected for its antithrombogenic properties and for its ability to adhere to one or more drug targets to be reduced or eliminated. The media can further be held in a cartridge for use in extracorporeal treatments such as those of hemoperfusion. Contacting the contaminated sample from the subject with the absorption medium allows for the separation of a portion of the drug target from the sample, producing a cleansed sample that can be infused into the subject. | 2021-01-14 |
20210008270 | BLOOD PURIFICATION DEVICE AND METHOD FOR PRODUCING SAME - A blood purification device includes a porous molded body containing an inorganic ion-adsorbing material and is characterized by the following: the concentrations of Mg, Al, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, Ga, Rb, Sr, Y, Zr, Mo, Ru, Ag, Cd, Sn, Cs, La, Pr, Sm, Gd, Tb, Ta, Au, Tl, Co, In, and Bi are each 0.1 ppb or less and the concentrations of Ba, Nd, Pb, And Ce are each 1 ppb or less in a physiological saline solution for injection both three months and six months after said physiological saline solution for injection is sealed in the blood purification device; and the number of fine particles having a size of 10 μm or more is 25 or less and the number of fine particles having a size of 25 μm or more is 3 or less in 1 mL of the physiological saline solution for injection. | 2021-01-14 |
20210008271 | METHOD AND DEVICE FOR THE EXTRACORPOREAL REMOVAL OF PATHOGENS AND/OR AN EXCESS OF COMPONENTS FROM A CELL SAMPLE OF A PATIENT - The invention relates to a method for the extracorporeal removal of pathogens and/or an excess of components from a cell sample of a human or animal patient suffering from an illness. The method comprises the steps: a) determination of at least one protein cluster (CMP) that is characteristic of the illness of the patient; b) preparation of the cell sample of the patient; and c) extracorporeal removal of components having the at least one determined protein cluster from the cell sample. The invention further relates to a device for carrying out said method. | 2021-01-14 |
20210008272 | SYSTEMS AND METHODS FOR OPTIMIZATION OF PLASMA COLLECTION VOLUMES - A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the volume/weight of anticoagulated plasma that is collected is optimized. In one example, a nomogram is provided that utilizes the donor's hematocrit to calculate the volume/weight of raw plasma within a plasma product having the maximum volume permitted by the FDA nomogram. In a plasmapheresis procedure having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the donor's increasing hematocrit, thus resulting in a greater total volume of plasma product to be collected during the plasmapheresis procedure. | 2021-01-14 |
20210008273 | DRUG SOLUTION ADMINISTRATION DEVICE - A drug solution administration device can prevent deformation resulting in bending of a plunger and a drug solution container during delivery of a drug solution. The drug solution administration device includes: a drug solution container having a cylindrical main body filled with drug solution; a housing that holds the drug solution container; a plunger that expels the drug solution in the drug solution container; and a fixing member that fixes the drug solution container to the housing. The housing includes a chassis having a support surface that supports the bottom surface of the main body of the drug solution container, and the fixing member includes a guide part mounted along the main body of the drug solution container from a side opposite the bottom surface of the main body of the drug solution container in a circumferential direction, and an engagement part engageable with the chassis of the housing. | 2021-01-14 |
20210008274 | DRUG SOLUTION ADMINISTRATION DEVICE AND CONTROL METHOD FOR DRUG SOLUTION ADMINISTRATION DEVICE - A drug solution administration device is able to prevent liquid supply of a drug solution from ending in a state where some of the drug solution remains in a drug solution container. The drug solution administration device includes a drug solution container filled with a drug solution and having a distal end opening, a housing that holds the drug solution container, a plunger that pushes out the drug solution in the drug solution container, a drive mechanism that advances the pusher toward the distal end opening of the drug solution container, a detection unit that detects a detection target part of the plunger to detect liquid supply completion of the drug solution based on a detection result, and a control unit that controls an operation of the drive mechanism. The control unit further advances the pusher after the detection unit detects the liquid supply completion. | 2021-01-14 |
20210008275 | PREFILLED SYRINGE, LIQUID MEDICINE ADMINISTRATION SYSTEM, AND SYRINGE PUMP - A prefilled syringe is disclosed, which includes: a liquid medicine; a barrel including a cylindrical body section containing the liquid medicine, and a nozzle section provided on a distal end side of the body section that discharges the liquid medicine; a cap sealing a distal end opening; a gasket sliding on an inner circumferential surface of the body section; a plunger that can be mounted to the gasket; and an RFID tag having a fixed location with respect to the outer circumferential surface and has an antenna and a memory, the antenna being structured from an antenna wire wound in a rectangle, an outer diameter of the body section being 14 mm to 33 mm, the maximum circumferential length of the antenna is 9 mm to 25 mm, and the circumferential length of the outer circumferential surface is 2.0 times to 7.0 times the maximum circumferential length of the antenna. | 2021-01-14 |
20210008276 | ADMINISTERING INSTRUMENT AND DRUG SOLUTION ADMINISTERING SYSTEM - An administering instrument is disclosed, which is capable of preventing a needle tube from coming out of a living body during administration of a drug solution and a drug solution administering system including the administering instrument and a medicinal solution administering device. The administering instrument includes a puncture part that has a contact surface contacting a body surface H of a user, a needle holding part for holding a needle tube, and a communication passage communicating with a lumen of the needle tube. The puncture part includes a fixing part that is disposed above the contact surface and fixes the first end part of the tube to the puncture part in a state where the first end part of the tube is inclined toward the contact surface of the puncture part. | 2021-01-14 |
20210008277 | ADMINISTERING INSTRUMENT AND DRUG SOLUTION ADMINISTERING SYSTEM - An administering instrument is disclosed, which is capable of preventing a needle tube from coming out of a living body during administration of a drug solution and a drug solution administering system including the administering instrument and a drug solution administering device. The administering instrument includes a first end part connected to a puncture part holding the needle tube, a second end part connected to a connector connectable to the drug solution administering device, and a tube body communicating from the first end part to the second end part, a tube configured to supply the drug solution from a lumen of a drug solution container to the needle tube via a communication part of the connector and a communication passage of the puncture part, and the tube body has a total length longer than a straight-line distance between the first end part and the second end part. | 2021-01-14 |
20210008278 | INFUSION SET WITH SAFETY DEVICE - An infusion base for attachment to a user of an infusion set comprises an adapter having a lower portion, an inner wall portion, and a gap between the lower portion and the inner wall portion. At least one of the lower portion and the inner wall portion is configured to receive an attachment. | 2021-01-14 |
20210008279 | Patch-Sized Fluid Delivery Systems and Methods - A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device. | 2021-01-14 |
20210008280 | SYSTEMS AND METHODS FOR DELIVERING A FLUID TO A PATIENT WITH REDUCED CONTAMINATION - An apparatus includes a cannula assembly, a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing includes an inlet port removably coupled to the cannula assembly and defines an inner volume. The fluid reservoir is fluidically coupled to the housing and configured to receive and isolate a volume of bodily fluid from a patient. The flow control mechanism is at least partially disposed in the inner volume. The actuator is operably coupled to the flow control mechanism and is configured to move the flow control mechanism between a first configuration, in which bodily fluid can flow, via a fluid flow path defined by the flow control mechanism, from the cannula assembly, through the inlet port and into the fluid reservoir, to a second configuration, in which the fluid reservoir is fluidically isolated from the cannula assembly. | 2021-01-14 |
20210008281 | Infusion Unit - Improvements in an infusion unit are disclosed. The infusion unit is a portable pump that can be used with patient that have wrist access or decubital PICC/MID-LINES without the risk of line accidently getting pulled. The infusion unit is in the shape of a conveniently shell that has an appearance of an arm cast. There are no hoses that extend beyond the body of the infusion unit and any vein penetration is completely covered under the body of the infusion unit. The secure enclosed unit prevents unauthorized tampering and entry into the unit. The medication dosing can be remotely monitored, fusion resumed, changed by nursing and the patient. The infusion unit has a wireless connection to a network to adjust medication and monitor vital signs, namely heart rate, O2 level and blood pressure that can be monitored and recorded for review. | 2021-01-14 |
20210008282 | Self-Controllable Load Spring Washer - Provided herein is a load spring washer configured for use with a medical injection device, having a main body having a proximal surface and a distal surface and one or more protrusions extending proximally away from the proximal surface of the main body. | 2021-01-14 |
20210008283 | Integrated Disinfection Device - Syringe tip caps are described herein. Such syringe tip caps may include a cup, a cap, a locking feature, a peelable seal and an absorbent material. The cap having locking features and a chamber appropriately sized to adapt to and interlock with an annular wall of the cup. | 2021-01-14 |
20210008284 | Pre-filled plastic syringe containing a VEGF antagonist - The present invention relates to a pre-filled syringe containing a VEGF antagonist and comprising a plastic barrel which is silicone-free, kits comprising this syringe and the use of the syringe for the administration of a VEGF antagonist in the treatment of ocular diseases. | 2021-01-14 |
20210008285 | SYRINGE, SYRINGE ASSEMBLY, AND MANUFACTURING METHOD OF SYRINGE - A syringe of a syringe assembly is provided with a body portion capable of being filled with a drug solution and a female port nozzle portion which extends from a distal end of the body portion and includes a communication port on a proximal end of the female port nozzle. The body portion includes a distal end wall surface and a side wall surface to which a liquid lubricant is applied. The distal end wall surface includes a concave portion arranged radially outside an inner edge portion adjacent to the communication port and concave in a distal end direction more than at least a part of the inner edge portion, and the concave portion is arranged to fully surround the communication port and may store the liquid lubricant. | 2021-01-14 |
20210008286 | Recording Device For Injection Device - A recording device for injection device includes a housing, a viewing window, a photographic module, a light splitting element and a signal transmission device. The housing is removably mounted on a dose scale window of an injection device. The viewing window is formed on a surface of the housing, and a viewing path is formed from the viewing window to the dose scale window. The photographic module is located on the housing, and provided with an image-capturing optical axis which is perpendicular to the viewing path. The light splitting element is located at an intersection of the viewing path and the image-capturing optical axis for guiding information located in the dose scale window to the photographic module and the viewing window, respectively. The signal transmission device is electrically connected to the photographic module for transmitting signals of the photographic module to an external device. | 2021-01-14 |
20210008287 | DATA COLLECTION APPARATUS FOR ATTACHMENT TO AN INJECTION DEVICE - A data collection device comprises an attachment assembly for attaching the data collection device to a dose setting dial of a medicament administration device and a sensor configured to detected an identifier provided on a surface of an internal component of the medicament administration device, the sensor comprising an ultrasound sensor configured to detect a geometric identifier formed on the surface of the internal component of the medicament administration device. A system comprises the data collection device and the medicament administration device. | 2021-01-14 |
20210008288 | STATE ESTIMATION FOR DRUG DELIVERY SYSTEMS - A flexible and reliable delivery state estimator or evaluator is provided for a drug delivery device. The proposed delivery status estimation architecture includes a position sensor that provides a continuous position sensor signal indicative of a current position of a component of the delivery device movable continuously from a first to a second component position, as well as a position discriminator that redefines the continuous position sensor signal to generate an approximate binary input signal on behalf of a state estimator. The discriminator absorbs any difficulty that may arise from a limited reproducibility or enhanced variability of the original continuous sensor signal, specifically including a user-originated signal spread in a movement of a needle protection sleeve of the delivery device. | 2021-01-14 |
20210008289 | GASKET PRESSING TOOL AND DRUG ADMINISTRATION TOOL USING THE SAME - A gasket pressing tool includes a syringe attachment member attached to an outer tube, a gasket pressing member that presses a gasket of a syringe, a pressing member biasing body accommodated in the gasket pressing member, a biasing body pressing tubular member that accommodates a rear end portion of the pressing member biasing body and has side portions provided with opening portions, and movement restriction members of the pressing member held by the tubular member and having engagement protrusions that enter through the opening portions of the tubular member. The pressing tool has an engaged state maintaining function for the engagement protrusion of the movement restriction member and the pressing member-side engagement portion of the pressing member, and an operation function for the engagement protrusion for releasing the engagement therebetween. | 2021-01-14 |
20210008290 | FAT SUCTION AND GRAFT SYRINGE HAVING NEGATIVE PRESSURE ADJUSTMENT MEANS - The present invention relates to a fat suction and graft syringe, and more specifically, to a fat suction and graft syringe having a negative pressure adjustment means, wherein a negative pressure state in a barrel can be maintained during a procedure only by pulling and releasing a plunger, and only by slightly rotating the plunger, the plunger can be pushed inside the barrel without being constrained by a multi-level holding plate and a single-surface rotation clip, whereby the syringe has enhanced convenience in the use and production thereof so that many practitioners accustomed to using a normal syringe can easily use the syringe without separately learning how to manipulate the syringe. | 2021-01-14 |
20210008291 | SYRINGES - Embodiments of this invention provide syringes calibrated for use with a predetermined liquid medication having an active pharmaceutical ingredient (API) at a particular weight per unit volume (w/v) concentration. Such syringes comprising a plunger and a barrel are configured such that the plunger, and/or an end portion of the plunger, is sealingly receivable through an opening at one end the barrel and within the barrel and slidingly moveable lengthwise within the barrel. This configuration allows formation of a reservoir inside the barrel into which the liquid medication may be loaded through an intake opening for the liquid medication at the other end of the barrel. Syringe barrels according to this invention possess line increments that form two or more graduated scales of API weight dosages extending lengthwise along the barrels. The increment lines provide for highly precise and accurate measurement of fine-increment weight dosages of the API. | 2021-01-14 |
20210008292 | Dosage Limiting Device - An adjustable dosage limiting device includes a member that interfaces to a plunger flange of a syringe and a barrel loop that slides along a barrel of the syringe. A locking mechanism, when engaged, fixes a distance between the member that interfaces to a plunger flange and the barrel loop, and hence, locks the barrel loop in place with respect to the plunger flange. Once locked in place, the adjustable dosage limiting device limits a dosage provided by the syringe based upon a distance between the member that interfaces to a plunger flange and the barrel loop as set by the locking mechanism. | 2021-01-14 |
20210008293 | DEVICE FOR PREPARING A DOSE OF MEDICAMENT ON DEMAND - The invention concerns a device for preparing a dose of medicament on demand, comprising at least one receptacle ( | 2021-01-14 |
20210008294 | POWER SUPPLY FOR DRUG DELIVERY SYSTEMS - A space-saving, autonomous power supply enables a monitoring unit to monitor a minimum number of delivery events of a drug delivery device. The monitoring unit has delivery status sensing means for monitoring a device delivery status, a status indicator with an indicator element such as an LED controllable to indicate delivery or module status to a user, and a power supply supplying power to the status sensing means and status indicator of the monitoring unit. The power supply has a peak current source, in particular a rechargeable battery or accumulator, providing a load current for operating the status sensing means and status indicator of the monitoring unit. The power supply has a recharge circuit with a converter and a charging resistor for providing a limited recharge current to the peak current source, plus a recharge source for repeatedly providing an optimized recharge source current to the recharge circuit. | 2021-01-14 |
20210008295 | PREFILLED SYRINGE - The prefilled syringe according to the present disclosure includes: a liquid medicine; a barrel including a cylindrical barrel body section that contains the liquid medicine, and a nozzle section that is provided on a distal end side of the barrel body section and configured to discharge the liquid medicine, the barrel being provided with a proximal end opening on a proximal end section of the barrel body section; a cap configured to seal a distal end opening provided on a distal end section of the nozzle section; a gasket configured to slide on an inner circumferential surface of the barrel body section; a syringe plunger configured to be mounted to the gasket and has an insertion section that can be inserted into the barrel body section; and an RFID tag mounted on the insertion section and including an antenna for communication and a memory. | 2021-01-14 |
20210008296 | INJECTION DEVICE WITH MEANS FOR DETERMINING EXPELLED DOSE - The present invention provides an injection device ( | 2021-01-14 |
20210008297 | GASKET PRESSING TOOL FOR SYRINGE OR LIQUID MEDICINE EJECTION TOOL, AND LIQUID MEDICINE ADMINISTRATION TOOL INCLUDING THE SAME - A liquid medicine ejection tool includes a syringe and a gasket pressing tool. The gasket pressing tool includes a gasket pressing member that can enter a gasket in the syringe. The gasket has an original lumen portion axial length, and a gasket-mounting portion of the gasket pressing member has an axial length longer than the original lumen portion axial length. When the gasket pressing member is mounted on the barrel of the gasket, a mounting portion distal surface of the gasket-mounting portion abuts on a lumen distal surface of a lumen portion of the gasket, and a gasket proximal surface pressing portion of the gasket pressing member becomes close to or abuts on a proximal surface of the gasket. | 2021-01-14 |
20210008298 | NOZZLE FIXTURE FOR AN INHALATION DEVICE - The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a fixture for a nebulizing nozzle to be used in such an inhalation device. A nozzle fixing assembly ( | 2021-01-14 |
20210008299 | EPIDERMAL SUSPENSION SPRAY DEVICE - A dermo-epidermal suspension spray device, said device comprising: a refill capsule (H) to contain skin pieces, said refill capsule (H) placed inside a sample loader (B); a stirrer mechanism to be connected to said refill capsule (H/ | 2021-01-14 |
20210008300 | Heat Units Using a Solid Fuel Capable of Undergoing an Exothermic Metal Oxidation-Reduction Reaction Propagated without an Igniter - A heating unit comprising an electrically conductive substrate. A solid fuel layer comprising a metal reducing agent, a metal containing oxidizing agent and a binder is coated on a surface of the substrate, the solid fuel layer having a solid fuel surface spaced from the substrate. A first electrode coupled to the substrate. A second electrode coupled to the solid fuel surface. A power supply is configured to be selectively coupled to the first and second electrodes to provide a voltage between the metallic substrate and the solid fuel surface. The voltage acts to propagate an exothermic metal oxidation-reduction reaction without the use of an igniter. | 2021-01-14 |
20210008301 | INSUFFLATION SYSTEM - Various implementations include an insufflation system for use with an endoscope. The insufflation system includes a housing, CO | 2021-01-14 |
20210008302 | INHALER - An inhaler for delivery of a medicament by inhalation is disclosed. The inhaler comprises the following components. An inhaler body for receiving a canister having a dispensing valve. A drive mechanism comprising a biasing means such as a spring and a moving component such as a yoke, the drive mechanism for driving the canister, when received in the inhaler body, from a rest position in which the valve is closed to at least an actuating position in which the valve is open. The drive mechanism drives the canister when the biasing means is released from a loaded configuration to move the moving component from a first position to a second position. A resetting mechanism, for example a mouthpiece cap arrangement for pushing upwardly on the yoke, for resetting the drive mechanism by moving the moving component from the second position to the first position and reloading the biasing means to the loaded configuration. A return mechanism for returning the canister from the actuating position to the rest position, wherein the return mechanism comprises a damping system, the damping system configured to enable the canister to automatically return from the actuating position to the rest position within a predetermined time period measured from the release of the biasing means from the loaded configuration. A method of operation of an inhaler is also disclosed. | 2021-01-14 |
20210008303 | VAPOR MIXING APPARATUS - A vapor blending device is provided, generally having a base, a carrier removably couplable to the base for carrying a first and second vapor generating system. The first and second vapor generating systems including airflow generators and controllers configured to vary voltage to each of the first and second vapor generating devices and the airflow generators. A container is positioned in fluid communication with the first and second vapor generating systems and configured to retain a quantity of vapor. In some examples, one controller is configured to cause the first vapor generating system to generate a quantity of a first vapor, and another controller is configured to cause the second vapor generating system to generate a quantity of a second vapor in a predetermined ratio to the quantity of the first vapor. The vapor in the predetermined ratio is stored in the container for later removal. | 2021-01-14 |
20210008304 | METERED DOSE INHALER ADD-ON DEVICE, OBSERVANCE IMPROVEMENT SYSTEM AND METHOD FOR IMPROVING OBSERVANCE OF USE IN METERED DOSE INHALERS - The present invention relates to an add-on device for a metered dose inhaler, an observance improvement system, and a method for improving observance of use in metered dose inhalers, the add-on device comprising an observance system housing component comprising an observance system with at least one pressure sensor; a mouthpiece component configured to fit, surround and removably engage with an exterior surface of a mouthpiece outlet provided on the metered dose inhaler; wherein said observance system housing is configured to fit and removably engage with said mouthpiece component; and said mouthpiece component is specifically adapted to conform to the exterior surface of the mouthpiece outlet of the metered dose inhaler without obstructing delivery of a dose of drug through said outlet. | 2021-01-14 |
20210008305 | INDUCTION SPACER FOR INHALER - A spacer for an inhaler includes a housing defining a chamber. The housing has an ambient port in fluid communication with ambient air, an inhaler port configured for attachment of an inhaler, and an outlet. The spacer further includes a fan for generating a flow of air through the chamber from the ambient port to the outlet. The fan may be powered by way of a spring such that the fan generates the flow of air as stored energy is released from a spring. Embodiments of the spacer may have an actuator for triggering a release of stored energy from the spring thereby actuating the fan. A mask or mouthpiece may be provided at the outlet. | 2021-01-14 |
20210008306 | INHALER WITH APERATURED POROUS SUPPORT ELEMENT - An inhaler article includes a body extending from a mouthpiece end to a distal end with an endpiece element at the distal end. A capsule cavity is defined within the body and extends a cavity length. An air inlet region is between the endpiece element and the capsule cavity. The air inlet region has an air inlet and an air passageway extending from the air inlet to the capsule cavity. The air passageway has an inner diameter less than an inner diameter of the capsule cavity. A porous support element defines a downstream end of the capsule cavity. The porous support element includes one or more apertures extending the length of the porous support element. | 2021-01-14 |
20210008307 | IHALER WITH VORTEX CAPSULE CAVITY - An inhaler article includes a body extending along a longitudinal axis from a mouthpiece end to a distal end with an endpiece element at the distal end. A capsule cavity is defined within the body and extends along the longitudinal axis a cavity length. The capsule cavity includes a helical feature on or in an inner surface of the capsule cavity. The helical feature extends along the cavity length. An air inlet region is between the endpiece element and the capsule cavity. The air inlet region has an air inlet and an Nair passageway extending from the air inlet to the capsule cavity. A porous element defines a downstream end of the capsule cavity. A mouthpiece air channel extends from the capsule cavity, through the porous element to the mouthpiece end. | 2021-01-14 |
20210008308 | ACCLIMIZATION THERAPY FOR FIRST TIME CPAP AND NIV USERS - A method of acclimatizing a patient to provide continuous positive airway pressure (CPAP) therapy, including operating a device for treating sleep disordered breathing (SDB). The device provides continuous positive airway pressure to the patient during sleep via a mask configured to provide a seal with respect to airways of the patient. The method comprises applying full therapeutic pressure during a first session, monitoring a mask pressure during application of the full therapeutic pressure, calculating a difference between the full therapeutic pressure and the mask pressure, comparing the difference to a threshold representing an acceptable level of leak, generating a first signal in response to said comparing, and in response to said first signal indicating a fault in the seal, decreasing an applied pressure to below the full therapeutic pressure during the first session in order to improve the seal of the mask against the patient's face. | 2021-01-14 |
20210008309 | COMBINATION RESPIRATORY THERAPY DEVICE, SYSTEM AND METHOD - A combination respiratory therapy management system creates a combined respiratory therapy prescription that can be executed by a combined respiratory therapy device to provide multiple coordinated respiratory therapies to a patient. The system can update the combined respiratory therapy prescription and implement the updates while the combined respiratory therapy device is in use. An integrated graphical user interface provides the patient and clinician with customization options and quick access to preselected operations of the combined respiratory therapy device. Additional features of the system enable remote access and control of the combination respiratory therapy device by remote clinicians. | 2021-01-14 |
20210008310 | CONTINUOUS POSITIVE AIRWAY PRESSURE (CPAP) DEVICE - A CPAP device includes a housing. A suction port is provided in a top plate portion of a casing of the air blower. The air blower chamber has a facing wall portion facing the top plate portion with a distance therebetween. A wall portion defining the air blower chamber is provided with an introduction port for introducing external air. In a space between the facing wall portion and the top plate portion, a flow adjustment portion that partitions the space into flow paths arranged side by side around a rotation axis is provided. An outer end portion and an inner end portion of each of the flow paths in a direction orthogonal to the rotation axis are respectively constituted of a first open end and a second open end, the first open end and the second open end being open along the direction orthogonal to the rotation axis. | 2021-01-14 |
20210008311 | METHODS AND APPARATUS WITH IMPROVED VENTILATORY SUPPORT CYCLING - A ventilator that delivers air at different pressures to a patient during inspiratory and expiratory cycles of breathing and that cycles from inspiratory to expiratory operation when the patient's respiratory flow passes a threshold level. The threshold generally increases from the beginning of inspiration to the end of inspiration. The increase can be linear over all or only a portion of the inspiratory cycle, and the threshold can be adjusted so that cycling is prevented during the initial portion of an inspiratory cycle. The minimum and maximum levels may both be functions of peak flow and the threshold may increase as a function of elapsed inspiratory time. The rate at which the threshold increases from a minimum level to a maximum level may be adjustable for individual patient needs and may be determined from previous breaths. | 2021-01-14 |
20210008312 | POWERING BREATHING APPARATUS - Described herein is a respiratory therapy system comprising: a primary power supply, a secondary power supply, and a breathing apparatus configured to provide respiratory therapy. The breathing apparatus comprises a controller. There is a connection between the primary power supply and the breathing apparatus configured to facilitate transmission of power and data between the primary power supply and the breathing apparatus. The controller is configured to monitor a parameter of the primary power supply, and disengage the primary power supply if the parameter differs from a parameter threshold. The controller is configured to engage the secondary power supply on disconnection of the primary power supply such that the breathing apparatus can continue operation without interruption. | 2021-01-14 |
20210008313 | Ventilator Setting Adjustment System - An automatic ventilator adjusting system has a three-way inline adapter coupled to 1) a breath sample line, 2) a ventilator (either invasive or non-invasive), and 3) a patient. The breath sample line is coupled to a Gas Exchange Monitor (GEM) and preferably has a female Luer lock end. Ventilator settings can be automatically set and/or adjusted using 1) an algorithm preferably having a feedback loop and 2) inputs including one or more of: gPaO | 2021-01-14 |
20210008314 | Endotracheal Tube To Bag Valve Device Connecting Assembly - An endotracheal tube to bag valve device connecting assembly for quick access to an endotracheal tube for suctioning includes a first tube and a second tube that are coupled to a hinge so that the first tube is positioned to be swiveled relative to the second tube to align the first tube with the second tube, wherein the first tube and the second tube define a pipe. A first end of the pipe is configured to selectively couple to a patient valve of a bag valve device. A second end of the pipe is configured to selectively couple to an endotracheal tube. The pipe is configured to allow flow of gas from the bag valve device to the endotracheal tube. The first tube is positioned to be swiveled on the hinge so that the second tube is configured to insert a suction tube into the endotracheal tube to clear an airway. | 2021-01-14 |
20210008315 | ENDOTRACHEAL TUBE HOLDER DEVICE - An endotracheal tube holder device is provided for securely holding an endotracheal tube to a patient during intubation. The tube holder device includes a support rail placed above a lip of a patient. An auxiliary clip is coupled to the support rail and slidably movable along the length of the support rail for holding an accessory device relative to the patients face. The auxiliary clip includes both a horizontal accessory clip and a vertical accessory clip to releasably retain the accessory device horizontally and vertically, respectively. A tube fastener is coupled to the support rail and includes a tube holder base, an adjustment clip coupled to the tube bolder base for laterally repositioning the tube holder base along the support rail, and a securement tie. The securement tie may be wrapped around a portion of the endotracheal tube to secure the tube to the tube holder base. | 2021-01-14 |
20210008316 | HEADGEAR WITH LOCK DISENGAGEMENT MECHANISM - A respiratory mask system is provided comprising a respiratory mask and a head engaging portion, wherein the head engaging portion is configured to couple to the respiratory mask to engage a wearer's head via a disengageable mechanism. The dis-engageable mechanism may comprise a linking member attached to the head engaging portion, a disengagement member attached to the respiratory mask and configured to receive the linking member, wherein the disengagement member is configured to be moveable between a first position and a second position, a control configured to allow a wearer of the mask to move the disengagement member towards the first position and one or more surfaces defined by the disengagement member and configured to exert a frictional force on the linking member. | 2021-01-14 |
20210008317 | COMPACT ORONASAL PATIENT INTERFACE - A breathing arrangement includes a patient interface, at least one inlet conduit, and a headgear assembly. The patient interface includes a mouth covering assembly including a cushion structured to sealingly engage around exterior of a patient's mouth in use, a nozzle assembly including a pair of nozzles structured to sealingly engage within nasal passages of a patient's nose in use, and a flexible element connecting the mouth covering assembly and the nozzle assembly. The at least one inlet conduit is structured to deliver breathable gas into at least one of the mouth covering assembly and the nozzle assembly for breathing by the patient. The headgear assembly is removably connected to at least one of the mouth covering assembly and the nozzle assembly so as to maintain the mouth covering assembly and the nozzle assembly in a desired position on the patient's face. | 2021-01-14 |
20210008318 | RESPIRATORY ASSEMBLY AND METHODS OF USING THE SAME - Nasal respiratory assembly comprises a pair of sheets. Each sheet defines an opening sized and shaped to fit over the nostril of a patient, with a ferromagnetic ring positioned at an underside of the sheet, with an upper side of the sheet configured for sealable engagement with the nostril. A pair of posts is provided, each post including a magnetic ring positioned at a first end and a receptacle positioned at a second end, the magnetic ring removably attachable to the ferromagnetic ring. A connector is also provided, the connector including a pair of channel openings at a post end, each channel opening sized and shaped to cooperate with one of the post receptacles to form a substantially airtight connection therewith, and an inlet at a vent end that is fluid communication with a flexible tubing connected to a fluid source. | 2021-01-14 |
20210008319 | BREATHING ASSISTANCE APPARATUS - In one embodiment, a nasal cannula is shaped to fit within a user's nares, where the nasal cannula includes at least one prong allowing high flow delivery of humidified gases and creates positive airway pressure in the patient's airway. The prongs have angled ends such that, in use, gases flowing through the prongs are directed to the user's nasal passages. The nasal cannula body is partially swivelling and preferably has a ball joint connector. In another embodiment the nasal cannula may have at least one flared end prong that preferably seals within a patient's nare. | 2021-01-14 |
20210008320 | CUSTOM PATIENT INTERFACE AND METHODS FOR MAKING SAME - A method of manufacturing a patient interface for sealed delivery of a flow of air at a continuously positive pressure with respect to ambient air pressure to an entrance to the patient's airways includes collecting anthropometric data of a patient's face. Anticipated considerations are identified from the collected anthropometric data during use of the patient interface. The collected anthropometric data is processed to provide a transformed data set based on the anticipated considerations, the transformed data set corresponding to at least one customised patient interface component. At least one patient interface component is modeled based on the transformed data set. | 2021-01-14 |
20210008321 | ORAL CAPNOGRAPHY ACCESSORY DEVICE - An oral capnography accessory device provides a pathway for sampling oral exhalations of carbon dioxide from a mouth of a patient. The device is used in combination with a bite block. The device includes a main body extending linearly along a longitudinal axis, latch arms extending from a buccal facing surface of the main body and forming a cavity into which the bite block is insertable, and tube attachment extending from a lingual facing surface of the main body. Tubing is insertable through a passageway therethrough of the tube attachment. The device is configured for use with a nose or face mask, and with a monitoring system. | 2021-01-14 |
20210008322 | METHOD FOR INHALATION EFFECT ON THE BODY, AND APPARATUS FOR IMPLEMENTING SAME - The invention allows for considerably improving the efficiency of inhalation treatment of various diseases and conditions in pulmonology, therapy, intensive treatment, anesthesiology, and sports medicine and is provided with new integral technical solutions while employing the opportunities of microelectronic technology and modern components. A modular structure of the apparatus simplifies its manufacture, ensures the ease of setting it up, and operation in various operating modes. When using the invention, monitoring of the ventilation indicators and patient condition with achieving his high safety level may be ensured; in sports medicine a problem of rehabilitation and training of athletes with the background of extreme loads and increased ventilation indicators is solved. | 2021-01-14 |
20210008323 | COMPLIANT COUPLER OR ADAPTOR - A CPAP device includes a flow generator including an outlet, a humidifier including an inlet, and an adaptor connector between the outlet of the flow generator and the inlet of the humidifier. The connector includes a flexible and conformable sealing portion that is movable to accommodate misalignment. | 2021-01-14 |
20210008324 | RESPIRATORY SYSTEM WITH HUMIDIFIER AND CONFORMABLE RESERVOIR - A humidifier for humidifying a flow of air to be delivered to a patient includes a base unit having at least one wall defining a receiving space. The base unit also includes a variable volume reservoir configured to hold a body of water and receive the flow of air to humidify the flow of air for delivery to the patient. The receiving space is configured to receive the variable volume reservoir and the variable volume reservoir is conformable to a shape of the receiving space. The humidifier further includes a heater for heating the body of water. | 2021-01-14 |
20210008325 | HUMIDIFICATION CHAMBER AND APPARATUS AND SYSTEMS INCLUDING OR CONFIGURED TO INCLUDE SAID CHAMBER - In one embodiment, there is provided a humidification chamber for use in a medical humidification system. The humidification chamber may comprise: a base and a top linked by a side wall to define the chamber, the chamber being configured to contain a volume of water; a gases inlet configured to receive a gases flow from a gases source; and a gases outlet, wherein the gases inlet is orientated relative to the side wall to introduce the gases flow to the humidification chamber at a direction substantially tangential to the side wall of the humidification chamber. | 2021-01-14 |
20210008326 | SYSTEMS AND METHODS FOR AN INDUCTIVELY HEATED ANESTHETIC VAPORIZER - Systems and methods are provided for delivering anesthetic agent to a patient. In one embodiment, an anesthetic vaporizer includes a vaporizing chamber configured to hold a liquid anesthetic agent, and an inductive heating element positioned exterior to the vaporizing chamber and housed within a gas-tight barrier, the inductive heating element operated to selectively heat a target. | 2021-01-14 |
20210008327 | SYSTEMS AND METHODS FOR A DISPOSABLE ANESTHETIC VAPORIZER - Systems and methods are provided for delivering anesthetic agent to a patient. In one embodiment, an anesthetic vaporizer includes a housing defining a sump, the sump configured to hold a self-contained supply of liquid anesthetic agent, a heating element electrically coupled to an electrical mating component, a gas inlet passage and a gas outlet passage, a manifold fluidically coupled to the gas inlet passage and the gas outlet passage, the manifold coupled to the housing and forming a gas-tight seal with the sump, and a quick disconnect pneumatic system coupled to the gas inlet passage and the gas outlet passage, sealing the gas inlet passage and the gas outlet passage from atmosphere. | 2021-01-14 |
20210008328 | HIATAL HERNIA TREATMENT - An improved hiatal hernia treatment enhances recovery after surgery by reducing a patient's pain at an area of treatment. The area of treatment contains a hiatal hernia and must be extensively divided before the hiatal hernia can be treated. The improved hiatal hernia treatment reduces pain through directed application of anesthetic via an applicator positioned within the area of treatment. Reduction of pain increases patient comfort reduces the need for pain medication, and lowers patient blood pressure to enhance recovery. | 2021-01-14 |
20210008329 | SLEEP PARALYSIS DETECTION DEVICE WITH EXTERNAL STIMULATION - The present invention relates to a device for providing an intervention for users who suffer from sleep paralysis. More specifically, the present invention illustrates a wearable device that measures the user's heart rate while they sleep. If the heart rate rises above a pre-set threshold level, then the device activates an element that exerts an external stimulus on the user causing the user to wake or providing a focal point for the user to overcome the sleep paralysis. | 2021-01-14 |
20210008330 | METHODS AND SYSTEMS OF VIRTUAL REALITY (VR) BEHAVIOR MODIFICATION - One aspect of the invention provides a system for virtual reality (VR) behavior modification. The system includes a VR headset adapted or configured to generate a VR environment comprising at least one VR object corresponding to a behavioral condition of a user; display the VR environment to the user; receive a response from the user comprising an interaction of the user with the at least one VR object; determine a behavioral modification score for the user based on the received response; and alter the at least one VR object based on the received response and the determined behavioral modification score. | 2021-01-14 |
20210008331 | SMART RELAXATION MASKS WITH WIRED EARPIECES - A relaxation mask includes: a main body that defines a pair of eye cavities; wiring; an earpiece that is coupled to the main body via the wiring; and a spring configured to bias the earpiece towards the main body. | 2021-01-14 |
20210008332 | LIGHT DIFFUSERS FOR SMART RELAXATION MASKS - A relaxation mask includes: a main body that defines a pair of eye cavities; and a light diffuser. The light diffuser includes a first lens that is disposed within a first one of the eye cavities. A first ledge is disposed along a top edge of the first lens and extends outwardly therefrom. A first light emitting component is supported on the first ledge and is configured to fire downward into the first lens. | 2021-01-14 |
20210008333 | SLEEP INTERVENTION EQUIPMENT, SYSTEM AND METHOD - A sleep intervention equipment, system and method are provided. The sleep intervention equipment includes a physical sign detection device, a first processor, and a sleep intervention device. The first processor is communicatively connected to the physical sign detection device and the sleep intervention device, respectively. The physical sign detection device is configured to detect a user's physical information without touching the user, and send the physical information to the first processor. The first processor is configured to determine a sleep stage and/or breath state of the user according to the physical information, and send a corresponding control instruction to the sleep intervention device according to the sleep stage and/or breath state of the user. The sleep intervention device is configured to perform a corresponding sleep intervention behavior in response to the control instruction. The sleep stage includes a waking state, an approaching waking state, or a sleep state. | 2021-01-14 |
20210008334 | EYESHADE AND ELECTROENCEPHALOGRAM DETECTION SYSTEM - An eyeshade and an electroencephalogram detection system are provided. The eyeshade includes an eyeshade main body; and an electroencephalogram acquisition unit, a controller and a heating unit which are disposed on the eyeshade main body. The electroencephalogram acquisition unit is configured to acquire a brain electrical signal of a wearer. The controller includes a converter and is configured to receive the brain electrical signal from the electroencephalogram acquisition unit, the converter is detachably coupled to the electroencephalogram acquisition unit and is configured to convert the brain electrical signal into a communication signal and transmit the communication signal to outside when coupled to the electroencephalogram acquisition unit. The heating unit is configured to heat an eye region of the wearer. | 2021-01-14 |
20210008335 | NON-PHARMACEUTICAL SYSTEMS AND METHODS OF TREATING THE SYMPTOMS OF FIBROMYALGIA - Non-pharmaceutical systems and methods of treating the symptoms of fibromyalgia are described. The method includes administering a therapeutically effective amount of a sensory stimulus to a person, wherein the sensory stimulus includes one or more visual stimuli and one or more auditory stimuli. | 2021-01-14 |
20210008336 | SYSTEMS, DEVICES AND METHODS FOR PERFORMING MEDICAL PROCEDURES IN THE INTESTINE - A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat at least one of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH). | 2021-01-14 |
20210008337 | Pistoning Prevention System (PPS) of Indwelling Foley Catheters - A pistoning prevention system (PPS) that will improve catheter associated urinary tract infection rates of an indwelling Foley catheter while maintaining reliability, comfort, & safety. With the PPS incorporated within a Foley catheter during manufacturing it will eliminate the excess stretch along a specific length of a Foley catheter that resides within the patient's urethra. The excessive amount and ease of stretch is responsible for the pistoning action of an indwelling Foley catheter moving in and out of the urethra. This action is responsible for the retrograde movement of bacteria outside the body & into the urethra, bladder, & kidneys increasing preventable infections. With much prevention work globally, the pistoning action of a Foley catheter is now known to be partially or wholly to blame for the attributed $340 million spent in the U.S. on healthcare costs & 13,000 associated deaths making this an immediate global patient safety emergency. | 2021-01-14 |
20210008338 | PERICARDIAL ACCESS - Medical devices and instruments, particularly pericardial access systems and devices and related methods are disclosed. Some example pericardial access devices may include a distally located, expandable skirt configured to engage the pericardium. When extended, the skirt may be wider than the tubular body of the device. Some example pericardial access devices may include an at least partially transparent, repositionable tip. | 2021-01-14 |
20210008339 | ENDOSCOPIC MEDICAL DEVICE AND METHOD OF USE - A medical device including a handle body having a proximal end and a distal end, a spool on the handle body and to move between the distal end and the proximal end of the handle body, a catheter extending from the distal end of the handle body, an actuator attached to the spool and extending through the catheter, such that the actuator is removably connected to one or more dispensable devices at a distal end of the catheter, a spool controller to prevent connection with another of the dispensable devices to the actuator after a predetermined number of dispensable devices have been dispensed by the medical device. | 2021-01-14 |
20210008340 | DELIVERY SYSTEM AND METHOD OF ASSEMBLING SUCH - A catheter delivery system ( | 2021-01-14 |
20210008341 | SHAFT ACTUATING HANDLE - Certain aspects relate to a handle mechanism that permits control of linear motion of a shaft secured within the handle via two different interfaces for actuating the linear motion. In some aspects, a rotational interface can allow for fine control linear positioning of the shaft, for example by allowing a user to rotate the rotational interface to extend or retract the shaft. In some aspects, a plunging interface can enable a faster linear motion, for example by implementing a biasing mechanism that releases to drive rapid linear motion. | 2021-01-14 |
20210008342 | GUIDE EXTENSION CATHETER - Guide extension catheters and related methods are disclosed. A guide extension catheter can comprise an elongate tube member, a push member, and an external manipulation member. The push member can be eccentrically coupled relative to the tube member and extend proximally therefrom for slidably positioning the tube member within and partially beyond a distal end of a guide catheter. The manipulation member can be coupled to a proximal end of the push member, where the manipulation member can be configured to secure the guide extension catheter in place during use by attaching to an external object such that the tube member and push member remain stationary without user engagement. | 2021-01-14 |
20210008343 | GUIDE EXTENSION CATHETER - Guide extension catheters and related methods are disclosed. A guide extension catheter can comprise an elongate tube member, a push member, and a removable support member. The push member can be eccentrically coupled directly or indirectly to the elongate tube member and can extend proximally therefrom for slidably positioning the elongate tube member within and partially beyond a distal end of a guide catheter. The removable support member can comprise a structure that surrounds at least a portion of the push member. The removable support member alone, or when placed over the push member, can be more rigid along its longitudinal axis than the elongate tube member and can have a cross-sectional | 2021-01-14 |
20210008344 | Bendable Sheath and Delivery System Using Bendable Sheath - A bendable sheath and a delivery system using the bendable sheath. The bendable sheath comprises a tube body ( | 2021-01-14 |
20210008345 | STEERABLE GUIDE CATHETER - A flexible guide tube having a deflectable distal end is disclosed with at least first and second tensioning lines coupled to a deflectable distal end of the flexible guide tube. The first tensioning line is configured to deflect the distal end of the flexible guide tube in a first direction and the second tensioning line is configured to deflect the distal end of the flexible guide tube in a second direction that is opposite the first direction. A handle is coupled to flexible tube, the handle having a medial portion with a longitudinal axis substantially parallel with at least a portion of the flexible guide tube, a first actuator disposed proximal the medial section, and a second actuator disposed distal the medial section. | 2021-01-14 |
20210008346 | MEDICAL TUBE HOLDER - A medical tube holder is proposed. The medical tube holder includes: holder bodies and surrounding an outer surface of a medical tube; and fluid pockets provided in the holder bodies to form a predetermined space and discharge fluid stored therein to the outer surface of the medical tube while at least a part of the fluid pockets is broken when pressed by an external force. The fluid pockets are formed in the medical tube holder, and when the fluid pockets are pressed by the external force, the fluid pockets are broken and a fluid (i.e., a lubricant) stored therein is discharged to an outer surface of the medical tube. Accordingly, a user may easily apply the fluid such as the lubricant by using the medical tube holder. | 2021-01-14 |
20210008347 | CATHETER ASSEMBLY WITH SEGMENTED STABILIZATION SYSTEM - A catheter assembly with segmented or step-wise deployment stabilization system includes a base or handle, puncture needle extending from the handle, and a deployment mechanism or mechanisms to selectively extend from the distal end of the needle for first length a hollow stabilizing component and as a second step to a second further length a stabilizing guide wire element. The hollow stabilizing component has some degree of flexibility as does the guide wire to minimize chance of damage to surrounding tissue. The user can feel resistance and have the opportunity to retract either component and attempt redeployment without a retraction of the puncture needle and a second poke of the patient's skin. In the example for peripheral venous catheterization, the system reduces the probability of blood vessel puncture. The deployment mechanism can have a guiding system which ensures the proper sequence of deployment. | 2021-01-14 |
20210008348 | CATHETER ASSEMBLY - A catheter assembly including a catheter carried by a catheter adapter, a needle having a sharp distal tip and disposed in the catheter such that in a first needle position, the needle extending beyond the catheter, a septum actuator having openings, the septum actuator disposed in the catheter adapter and configured to pierce a septum, and a spring clip disposed in the septum actuator and engaging the openings of the septum actuator in the first needle position. | 2021-01-14 |
20210008349 | MAGNETIC CATHETER SYSTEM AND METHODS - A catheter system may include a needle assembly coupled to a catheter adapter. The needle assembly may include a housing, an introducer needle, a distal opening, a first magnet, and a second magnet. In response to proximal withdrawal of the introducer needle, the first magnet may move towards the second magnet, which may block the distal opening and/or prevent blood from leaking out the distal opening. | 2021-01-14 |
20210008350 | CATHETER SYSTEM FACILITATING REDUCED DRAG FORCE - A catheter system may include a needle assembly coupled to a catheter adapter. The needle assembly may include a housing, an introducer needle, a proximal opening, a distal opening, and a needle tip shield feature. A distal tip of the introducer needle may be configured to be proximally withdrawn from a first position to a second position in which a bump feature of the introducer needle contacts and is prevented from moving through the proximal opening. In response to withdrawal of the distal tip proximally from the second position to a third position, the housing may move proximally, and the needle tip shield feature may be released to block the distal opening. The needle tip shield feature may not contact the introducer needle when the distal tip moves proximally from the first position to the second position and from the second position to the third position, which may reduce a friction-based drag force on the introducer needle. | 2021-01-14 |
20210008351 | INTEGRATED COIL VASCULAR DEVICES - The present disclosure relates to vascular devices such as guidewires and microcatheters having integrated coil sections for optimizing torquability, flexibility, and ability to shape and maintain the distal tip. A guidewire device includes a core and a tube structure coupled to the core such that at least a portion of the core passes into the tube structure. A distal section of the tube structure includes a spiral cut arrangement that configures the distal section as an integral coil integrally incorporated as part of the tube structure. The integrated coil configuration increases the flexibility of the tube structure to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device. | 2021-01-14 |
20210008352 | HOUSING FOR STORAGE AND MANIPULATION OF A SURGICAL GUIDE WIRE - A housing has a spiral passageway which contains a catheter which may be manually extracted from the housing by means of a wheel having a polygonal or otherwise textured circumferential surface and mounted on a shaft which extends through a non-circular bearing defined in an outer portion of the housing. An inner portion of the wheel extends into the spiral passageway adjacent the wire catheter and an outer portion of the wheel outwardly from the housing whereby the upper surface of the knob can be manipulated by a member of the surgical team in one direction and the wire catheter below the knob will be advanced in the opposite direction. The non-circular bearing has a generally circular outer portion in which the textured surface of the knob is only intermittently in contact with the catheter whereby the wire catheter may be advanced, and a generally linear inner portion sloping inwardly towards the catheter. When the knob's shaft is held loosely in the outer portion of the bearing, the wire catheter is free to travel. However when the knob's shaft is moved into the sloping portion of the bearing, the operator can push the knob in one direction to force the knob against the wire catheter and lock the catheter into intimate contact with the lower surface of the passageway, and in the opposite direction to retract the knob slightly away from the catheter thereby permitting limited movement of the catheter relative to the housing. | 2021-01-14 |
20210008353 | Steerable Guidewire and Method of Use - This invention is a transvascularly placed steerable guidewire, further including internal steerability and the ability to articulate in a direction at right angles to its longitudinal axis at or near its distal end. The steerable guidewire is generally fabricated from stainless steel and includes an outer tube, an inner tube, hub structures, and a distal articulating region. The steerable guidewire can be advanced through a body lumen in its straight configuration and then be selectively articulated or curved to permit negotiation of tortuous curvature. The steerable guidewire hub can be removed to permit advancement of catheters over its proximal end followed by re-attachment of the hub to permit deflection of the distal end of the steerable guidewire. Removal of the hub can result in a limp guidewire or maintenance of a forced curvature of the distal end of the guidewire. | 2021-01-14 |
20210008354 | ANGIOPLASTY OF CALCIFIED ARTERIES - A medical device comprises a catheter having a lumen extending between a distal end and a proximal end of the catheter and a balloon having an expandable interior volume coupled to the distal end of the catheter with its interior volume in fluid communication with the lumen of the catheter. A spring-loadable mechanical structure is disposed within the balloon configured to snap between first and second configurations upon actuation by an actuation mechanism. Upon actuation, the spring-loadable mechanical structure creates pressure pulses in fluid within the balloon interior volume which are transmitted to the walls of the balloon to disrupt calcified material or other hardened material within a vessel of the human or animal body in which the balloon is situated. | 2021-01-14 |
20210008355 | GUIDE EXTENSION CATHETER - This patent document discloses guide extension catheters for use with a predefined length guide catheter and related methods for treating blood vessel lesions and abnormalities. A guide extension catheter can include a push member, an elongate tube member, and a balloon radially surrounding a portion of the elongate tube member. The balloon can include an inflatable tube coupled to an elongate shaft having a lumen for receiving inflation fluid, and the inflatable tube can be coiled in a helical manner around the elongate tube member. A bioactive layer can coat an outer surface portion of the balloon and, when the balloon is inflated, one or more drugs of the bioactive layer can be received by the blood vessel. Inflation of the balloon can engage the elongate tube member with an inner surface of the blood vessel and/or an inner surface of the guide catheter. | 2021-01-14 |
20210008356 | PARANASAL SINUS FLUID ACCESS IMPLANTATION TOOLS, ASSEMBLIES, KITS AND METHODS - An implantation tool to implant a paranasal sinus fluid access implant device to fluidly connect the lacrimal apparatus in the orbit with a paranasal sinus has a securement mechanism reconfigurable from a securement configuration to secure the implant device to a mounting portion of a carrier member to a released configuration to release the implant device from the carrier member, and with a release mechanism disposed at least partially in an interior working space housed within the implantation tool. An implantation method with an approach through the palpebral fissure advances the implant device through a surgical route mostly under tension. | 2021-01-14 |
20210008357 | Girth adjustable device - A girth adjustable device for dilation and stretch of body orifices for medical applications, massage, body orifice improvement and activities pleasurable to the body, that can repeatedly, gradually increase and decrease a uniform and sustainable pressure against the entire lateral surface area of body orifices. The girth adjustable device comprises at least one controller, a housing, at least one threaded shaft, at least one module, a plurality of shaft members and at least one sheath. The part of the girth adjustable device that has to be inserted into body orifices is the shaft. In a body orifice, the user increases and decreases the girth size of the shaft via the controller. | 2021-01-14 |
20210008358 | IMPLANT CAPABLE OF RELEASING DRUG, AND MANUFACTURING AND USAGE METHODS THEREFOR - The invention provides a drug-releasing implant, comprises the implant for fixing the surgical site, said implant is provided with the drug cavity for storing drug, said drug cavity is filled with liquid drug; said implant is further provided with micro pipeline, the micro pipeline passes through the drug cavity and the surface of the implant, the drug in the drug cavity is slowly released to the surgical site through the micro pipeline. The implant can effectively fix the bone at the surgical site (fracture site), after the surgery is completed, the drug set in implant's drug cavity slowly releases to the fracture site through micro pipeline, achieve local application of drug and reduce oral medication, so that decrease the fracture patients' medical expenses and psychological stresses, improve the utility of the device. | 2021-01-14 |
20210008359 | 3D Printed Microneedles for Microencapsulated Mammalian Cell Extrusion - A 3D printed biocompatible drug delivery device is provided having a fluid delivery channel distinguishing three segments and a receiving chamber with an array of microneedles. The three segments of the delivery channel are stagnation zones before a drug is extruded and whereby an inverted funnel provides an increasing extrusion surface servicing the drug to the array of microneedles. The design of the device with its flow-related components circumvents the challenge of colloidal stability associated with multi-phase formulations leading to nozzle blockage. Qualitative screening cytotoxicity tests pre and post-extrusion through the drug delivery device using mammalian cells rule out cytotoxicity and outline equivalent viability to control treatments. The biocompatibility results suggest that the fluid delivery design, the photoresin selected as well as the fabrication and sterilization may be extended over a range of regenerative medicine and drug delivery applications. | 2021-01-14 |
20210008360 | Adhesion Member and Microneedle Patch - The present invention chiefly aims at providing a new patch which is excellent in the fixability to the skin, regarding the patch carrying a microneedle array. | 2021-01-14 |
20210008361 | MEDICAL TUBING SYSTEM - A medical tubing system whereby the tubing is configured to break apart when subjected to forces, thereby reducing the risk of patient strangulation through accidental entanglement or deliberate self-harm attempt. | 2021-01-14 |
20210008362 | A FLEXIBLE DOUBLE LUMEN TUBE AND A TUBE COUPLING SYSTEM FOR SAME - A tube coupling system serves for providing annular flow through a flexible annular double lumen tube between fluid reservoir(s) and flexible connection pieces of an annular double lumen device. The tube coupling system has a first coupling component and a second coupling component and an end fitting system. The first coupling component that has a female coupling part and a male coupling part adapted for coupling to a proximal end of the flexible annular double lumen tube. The second coupling component has a second interior pipe that axially extends inside a second exterior pipe, a first end fitting adapted for coupling to at least the female coupling part of the first coupling component, and a second end fitting adapted for coupling to any of the flexible annular double lumen tube or the flexible connection pieces of an annular double lumen device. | 2021-01-14 |
20210008363 | NANOPILLAR ELECTRODE DEVICES AND METHODS OF RECORDING ACTION POTENTIALS - This disclosure provide a nanopillar electrode device, comprising a substrate patterned with a plurality of metal pads. The device may further comprise a plurality of nanopillars electrode arrays, wherein each nanopillar electrode array is attached to the substrate above a metal pad and electrically connected to the pad. The device may further comprise and a chamber surrounding the nanopillar electrodes, which can be used for culturing cells of interest for recording action potentials. The nanopillar electrode device may be configured to apply a voltage through the nanopillar electrodes from a voltage source. Nanopillar electroporation may be used to increase the permeability of cell membranes to allow intracellular recording. Also provided are methods of device fabrication, and methods of use. | 2021-01-14 |
20210008364 | SANDWICH ASSEMBLY SCHEME FOR THIN FILM ELECTRODE ARRAY AND INTEGRATED CIRCUITS ON BOTH SIDES OF PRINTED CIRCUIT BOARD (PCB) AND METHOD OF MANUFACTURE - Disclosed is a sandwich assembly containing a thin film electrode array for use with high density electrodes. To minimize the volume required by the associated electronics, the electrode array and integrated circuits are sandwiched over a Printed Circuit Board (PCB), which may have other integrated circuits on an opposite side. Among other things, the disclosed apparatus, system, and method improve over previous systems by providing holes and vias that facilitate communication between a custom chip above the PCB and a field-programmable gate array (FPGA) below. The thin film electrode array can be fastened by bucking a pillar of stacked gold or other metal balls to rivet the thin film flex circuit. The system can include a thin film array having embedded wire traces and holes, a PCB having vias aligned with the holes, chips including an analog-to-digital converter (ADC) sandwiching the thin film, and solder connections from the chips through the holes to the vias. | 2021-01-14 |
20210008365 | Pulsed Passive Charge Recovery Circuitry for an Implantable Medical Device - The problem of a potentially high amount of supra-threshold charge passing through the patient's tissue at the end of an Implantable Pulse Generator (IPG) program is addressed by circuitry that periodically dissipates only small amount of the charge stored on capacitances (e.g., DC-blocking capacitors) during a pulsed post-program recovery period. This occurs by periodically activating control signals to turn on passive recovery switches to form a series of discharge pulses each dissipating a sub-threshold amount of charge. Such periodic pulsed dissipation may extend the duration of post-program recovery, but is not likely to be noticeable by the patient when the programming in the IPG changes from a first to a second program. Periodic pulsed dissipation of charge may also be used during a program, such as between stimulation pulses. | 2021-01-14 |
20210008366 | NERVE CUFF DEPLOYMENT DEVICES - Nerve cuff deployment apparatuses and methods of using them to deliver a nerve cuff electrode to a target nerve trunk. | 2021-01-14 |
20210008367 | Reducing Motility of Cancer Cells Using Tumor Treating Fields (TTFields) - The spreading of cancer cells in a target region can be inhibited by imposing a first AC electric field in the target region for a first interval of time, with a frequency and amplitude selected to disrupt mitosis of the cancer cells; and imposing a second AC electric field in the target region for a second interval of time, with a frequency and the amplitude selected to reduce motility of the cancer cells. The amplitude of the second AC electric field is lower than the amplitude of the first AC electric field. | 2021-01-14 |
20210008368 | NEUROMODULATION DEVICE AND METHOD FOR USE - Neuromodulation devices and methods of their use are described in which a therapeutic device is configured to generate a treatment for treating pain such as the reduction of the symptoms of chronic and acute pain as well as for treating other conditions. The neuromodulation device generates an output electrical signal in the form of pulses with a fast rise-time spike waveform followed by a longer-duration, lower amplitude primary phase waveform. The output signal includes a broad range of frequency components, with time constants tuned so as to interact with specific cell membrane or cellular components. The output signal may be conducted to the patient via electrodes. The pulses are triggered at variable intervals which prevent habituation. | 2021-01-14 |