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01st week of 2012 patent applcation highlights part 32
Patent application numberTitlePublished
20120003101CASTING METHOD FOR MANUFACTURING A WORK PIECE - A method for manufacturing a work piece is provided. The method includes preparing fibreglass in a mould, preparing a closed mould cavity around the fibreglass, flushing the closed mould cavity with an oxygen-free gas, injecting resin in the closed mould cavity, and curing the casted work piece. Furthermore, a work piece manufactured by the above method is provided2012-01-05
20120003102DENSE VERTICALLY CRACKED THERMAL BARRIER COATINGS - This invention relates to dense, vertically cracked thermal barrier coatings made from high purity yttria or ytterbia stabilized zirconia powders. The high purity yttria or ytterbia stabilized zirconia powder consisting essentially of less than about 0.01 weight percent silicon dioxide (silica), less than about 0.002 weight percent aluminum oxide (alumina), less than about 0.005 weight percent calcium oxide, less than about 0.005 weight percent ferric oxide, less than about 0 to about 0.002 weight percent magnesium oxide, less than about 0 to about 0.005 weight percent titanium dioxide, from about 1.5 to about 2 weight percent hafnium oxide (hafnia), from about 6 to about 25 weight percent yttrium oxide (yttria), less than 0.1 weight percent other impurity oxides, and the balance zirconium oxide (zirconia) and the balance zirconium oxide (zirconia). The thermal barrier coatings are intended to be used in cyclic thermal environments such as for gas turbine blades, vanes and seal surfaces exposed in the hot section of gas turbine engines.2012-01-05
20120003103TURBINE ROTOR ASSEMBLY - A turbine rotor assembly (2012-01-05
20120003104PIEZO-CONTROLLED AND-OR PRESSURE RIPPLE COMPENSATING FLUID SEPARATION PUMP - An embodiment discloses a fluid pump for use in a fluid separation system for separating compounds of a fluidic sample in a mobile phase, the fluid pump comprising a reciprocatable piston configured for moving the mobile phase, a pump drive configured for driving the reciprocatable piston, and a control unit configured for controlling the pump drive so that pressure ripples in a pressure profile of the fluid pump are at least partially compensated to thereby bring the pressure profile in accordance with a predefined target characteristic. Another embodiment discloses a fluid pump for use in a fluid separation system for separating compounds of a fluidic sample in a mobile phase, the fluid pump comprising a reciprocatable piston configured for moving the mobile phase, and a pump drive configured for driving the reciprocatable piston using a piezomechanism.2012-01-05
20120003105DRY VACUUM PUMP - The invention pertains to a dry-type vacuum pump comprising: 2012-01-05
20120003106TUNABLE CHOKE TUBE FOR PULSATION CONTROL DEVICE USED WITH GAS COMPRESSOR - A method and system for reducing pulsation in a gas compressor system. A pulsation control device, such as a filter bottle or side branch absorber, is installed at a port into some location on the compressor system. The pulsation control device has a choke tube with a variable cross-sectional area, such as by having multiple conduits that may be opened or closed or a diameter that may be varied. In operation, the cross sectional area of the choke tube is varied depending on the compressor speed.2012-01-05
20120003107PUMPS AND PUMP HEADS COMPRISING VOLUME-COMPENSATION FEATURE - A fluid pump having a pump housing that includes at least one expansion joint, provides volume compensation, as needed, to adjust for changes in pressure in the pump housing. Various embodiments automatically and passively reduce static pressure in the pump housing associated with a freezing event, thereby preventing damage to the pump head. Volume compensation is achieved by employing, in each expansion joint, a dynamic seal that allows relative movement of two portions of the pump housing, and a bias that provides a selected counter-force to the movement of the housing portions. The subject pumps are particularly suited for use in automotive and other rugged applications, in which fluid pumps may experience recurring freezing events.2012-01-05
20120003108CENTRIFUGAL PUMP APPARATUS - A centrifugal blood pump apparatus includes an impeller provided in a blood chamber, first and second permanent magnets provided in one surface and the other surface of the impeller respectively, a third permanent magnet provided in an inner wall of the blood chamber, and a magnetic element and a coil for driving the impeller to rotate with a diaphragm being interposed. First and second grooves for hydrodynamic bearing different in shape and depth from each other are formed in the inner wall of the blood chamber facing the impeller, and third and fourth grooves for hydrodynamic bearing different in shape and depth from each other are formed in the diaphragm facing the impeller. The second and fourth grooves for hydrodynamic bearing generate high hydrodynamic pressure when the impeller is activated to rotate, while the first and third grooves for hydrodynamic bearing generate high hydrodynamic pressure when the impeller steadily rotates.2012-01-05
20120003109BLOWER FAN - A blower fan includes an impeller cup; a shaft including an end arranged to project axially upward from the impeller cup; a rotor magnet fixed to the shaft; a first bearing and a second bearing arranged axially above and below, respectively, the impeller cup; a first bearing support portion and a second bearing support portion arranged to support the first and second bearings, respectively; and a first housing and a second housing arranged on axially upper and lower sides, respectively. The first and second housings are joined to each other at an axial level higher than an axial position of a joint between the second housing and a second joining portion arranged to join the second housing and the second bearing support portion to each other.2012-01-05
20120003110PUMP FOR DOSING FLUIDS - A pumping assembly is provided which is suitable for use in a variety of dosing pumps. The pumping assembly comprises a pump body with a pump bore, and a sleeve fixed within the pump bore. The sleeve has a first end, a second end and a sleeve bore. A plunger is adapted to enter the first end of the sleeve and to reciprocate within the sleeve bore. The sleeve has at least one port to allow fluid flow through a wall of the sleeve. The, or each, port is elongated in a direction substantially orthogonal to a direction of reciprocation.2012-01-05
20120003111MECHANICAL SYSTEM FOR MOVEMENT ALONG A HOUSING AXIS - A mechanism for moving elements in a fluid filled housing a pump with the element to be moved attached rigidly to the pump or to a port assembly connected to the pump. The pump assembly or port assembly moves as a result of differential pressure created between a first and a second chamber separated from each other by the pump assembly or port assembly. Movement of the fluid in one direction increases or decreases pressure, the pressure change resulting in a net force in one direction or the other.2012-01-05
20120003112UNIAXIAL ECCENTRIC SCREW PUMP - Provided is a uniaxial eccentric screw pump which can prevent the life of a bearing sliding portion from decreasing due to a thrust load applied from a high pressure side to a low pressure side. An external thread-like motor directly coupled with a driving shaft is rotated and eccentrically moved with respect to the axis of a stator to deliver a fluid from an intake side to a discharge side. The pump is provided at an end of the discharge side of the motor and extends toward the discharge side in the axial direction of the stator. The uniaxial eccentric screw pump includes an annular small-diameter portion and a seal member. The seal member 2012-01-05
20120003113SCREW COMPRESSOR - A screw compressor includes a casing, a screw rotor, an oil sump containing lubricant oil, a lubrication passage and a flow rate controller. The screw rotor is inserted in a cylinder portion of the casing to form a fluid chamber. The screw rotor rotates to suck a fluid into the fluid chamber for compression. The lubrication passage supplies the lubricant oil in the oil sump to the fluid chamber due to a difference in pressure between the oil sump and the fluid chamber. The flow rate controller reduces a flow rate of the lubricant oil supplied to the fluid chamber in accordance with a decrease in operating capacity of the screw compressor.2012-01-05
20120003114Nanostructured Mn-Al Permanent Magnets And Methods of Producing Same - A bulky consolidated nanostructured manganese aluminum alloy includes at least about 80% of a magnetic τ phase and having a macroscopic composition of MnXAlYDoZ, where Do is a dopant, X ranges from 52-58 atomic %, Y ranges from 42-48 atomic %, and Z ranges from 0 to 3 atomic %. A method for producing a bulky nanocrystalline solid is provided. The method includes melting a mixture of metals to form a substantially homogenous solution. The method also includes casting the solution to form ingots, measuring compositions of the ingots; crushing the ingots to form crushed powders, and milling the crushed powders to form nanocrystalline powders. The method further includes verifying the presence of τ phase and determining the amount of the τ phase, and simultaneously consolidating the nanocrystalline powders into a bulky nanocrystalline solid and undergoing phase transformation from ε phase to at least 80% τ phase, β and γ2 phases.2012-01-05
20120003115PROCESS FOR PRODUCTION OF SEMISOLIDIFIED SLURRY OF IRON-BASE ALLOY; PROCESS FOR PRODUCTION OF CAST IRON CASTINGS BY USING THE PROCESS, AND CAST IRON CASTINGS - A process for the production of a semi-solidified iron alloy slurry having a crystallized solid phase and a residual liquid phase, wherein a material having a hypoeutectic cast iron composition is used, and an additive agent having a boiling point that is lower than at least a crystallization initiation temperature of primary crystals of the material is added to a melt of the material when the melt temperature is within a specific temperature range of not lower than the crystallization initiation temperature of the primary crystals and not greater than a temperature that is 50° C. higher than the crystallization initiation temperature, to thereby simultaneously conduct the stirring of the melt by the boiling of the additive agent and the cooling of the melt to a temperature falling within a semi-solidification temperature range thereof.2012-01-05
20120003116AUSTENITIC STAINLESS STEEL - An austenitic stainless steel, which consists of by mass %, C≦0.02%, Si: 0.01 to 0.50%, Mn: 0.01 to 2.0%, Cr: 24 to 26%, Ni: 19 to 22%, Mo: more than 0.10% to less than 0.50%, N: more than 0.04% to not more than 0.15%, and one or two elements selected from Nb≦0.30% and V≦0.40%, with the balance being Fe and impurities, and among the impurities P≦0.030%, S≦0.002% and Sn≦0.015%, and satisfies [2.5≦36Nb+53V+15N≦25.0] and [S+{(P+Sn)/2≦−5.76×102012-01-05
20120003117PROCESS FOR MANUFACTURING STEEL BLANKS - The invention relates to a manufacturing process for steel blanks. The invention relates in particular to a manufacturing process of a steel blank comprising electroslag remelting (ESR—ElectroSlag Remelting) or vacuum arc remelting (VAR—Vacuum Arc Remelting) to obtain very good mechanical properties. The blanks obtained can be used especially in the field of the manufacture of pressurised equipment elements and especially cannon tubes.2012-01-05
20120003118PROCESSING OF TITANIUM-ALUMINUM-VANADIUM ALLOYS AND PRODUCTS MADE THEREBY - A method of forming an article from an α−β titanium including, in weight percentages, from about 2.9 to about 5.0 aluminum, from about 2.0 to about 3.0 vanadium, from about 0.4 to about 2.0 iron, from about 0.2 to about 0.3 oxygen, from about 0.005 to about 0.3 carbon, from about 0.001 to about 0.02 nitrogen, and less than about 0.5 of other elements. The method comprises cold working the α−β titanium alloy.2012-01-05
20120003119ANTIMICROBIAL PEPTIDES - The present invention is directed to a method for disinfecting or sterilizing food, particularly, fresh produce, fruits and vegetables, by applying antimicrobial polypeptides (AMP). The AMP used in the present invention consists of from 13 to 20 amino acids and has an amphipathic alpha helix structure, wherein 3 or more of the amino acids form a positively charged domain extending axially along the alpha helix.2012-01-05
20120003120HEAT RECOVERY IN BIOWASTE STERILIZATION - According to the present invention a method for heat recovery in a device for the sterilization of biological material is provided. The present method eliminates the risk of contaminating the sterilized effluent with unsterilized biological material via the heat recovery system. In a device according to the invention, a heat recovery circuit is provided for transferring heat from the sterilized effluent stream to the biologically hazardous feed stream. Protection against contamination through leaks is obtained by maintaining at all times a pressure difference preventing biologically hazardous material from bypassing the heat treatment and flowing in the direction of the sterilized material.2012-01-05
20120003121SAMPLE ANALYZER - A sample analyzer is provided that does not require a plurality of reagent containers containing the same type of reagent to be connected, that can continue measurement even when a reagent container becomes empty, and that allows the timing of replacement of the reagent container to be recognized suitably. A reagent storage section is provided that is connected to a reagent container containing a reagent through a fluid channel and that stores the reagent transferred from the reagent container. A message for prompting replacement of the reagent container is outputted when it is detected that the remaining amount in the reagent container is a predetermined amount or less. A message for prompting to suspend sample measurement in the measurement section is outputted when it is detected that the remaining amount in the reagent storage section is a predetermined amount or less.2012-01-05
20120003122FLOW CONTROLLER ASSEMBLY FOR MICROFLUIDIC APPLICATIONS AND SYSTEM FOR PERFORMING A PLURALITY OF EXPERIMENTS IN PARALLEL - A flow controller assembly for microfluidic applications includes at least one microfluidic flow controller, which includes a microfluidic chip, a thermal energy transmitter, a flow sensor for measuring the flow rate of a fluid running through the flow controller and a data control unit. The data control unit, which is connected to the flow sensor by a first data connection which allows the data control unit to receive flow rate measurement data from the flow sensor, and which is also connected to the thermal energy transmitter by a second data connection allows the data control unit to influence the thermal output of the thermal energy transmitter, includes a data processing unit that determines the difference between the measured flow rate and a preset desired flow rate and to regulate the thermal output of the thermal energy transmitter in order to obtain or maintain the desired flow rate.2012-01-05
20120003123FECAL SAMPLING DEVICE AND METHOD - A device for testing a specimen comprising a first panel, a metering aperture structure having a plurality of metering apertures formed therein for receiving the specimen therethrough, a second panel opposite the first panel, a sheet disposed between the first and second panels, the sheet including a test area aligned with the plurality of metering apertures, a spacer element disposed between the first panel and the sheet, wherein the metering aperture structure is spaced away from the test area thereby improving readability of the testing. A method of manufacturing a specimen testing device is also disclosed.2012-01-05
20120003124CHEMICAL ANALYSER - A chemical analyser analyses a sample for a target chemical. The sample and reagent are added to a measurement cell until a detectable change is observed. A reference compound, which does not take part in the reaction between the target chemical and reagent, is added to the reagent. By measuring the concentration of the reference compound, the amount of reagent used may be determined. In one embodiment, a mechanism introduces the sample, adds reagent, mixes, cleans, and flushes the measurement cell, which incorporates a longitudinal chamber having inlets for the sample and reagent and an outlet for measured sample/reagent mixtures. A detector located in or adjacent to the chamber between the inlets and outlet and a piston movable in the chamber carries seals such that movement of a piston sequentially opens the inlets and expels the fluid. The analyzer also includes a device that delivers reagent to a measurement cell.2012-01-05
20120003125EXHAUST GAS PURIFICATION APPARATUS - An exhaust gas purification apparatus 2012-01-05
20120003126High Intensity Air Purifier - This document describes a high intensity air purifier (HAIP), a super oxidation purifier, and a controller for controlling operation of any of various purification systems. In some implementations, a HAIP includes an air purifier system coupled within a housing having an air inlet and an air outlet. The air purifier system includes a pre-filter coupled to the air inlet, an axial fan for receiving and forwarding air from the air inlet. The air purifier system further includes a UV reaction chamber having a UV-light source for providing UV light to the forwarded air from the air inlet and a reflective lining to reflect the provided UV light, to provide UV purified air from the UV reaction chamber. The air purifier system further includes a chemical catalyst cartridge for receiving the UV purified air from the UV reaction chamber, for further purifying the UV purified air, and a post filter coupled to the air outlet.2012-01-05
20120003127CATALYST SEPARATION SYSTEM - A catalyst separation system is provided with: a reactor where hydrocarbons are synthesized by a chemical reaction of a synthesis gas including carbon monoxide gas and hydrogen gas as main components, and a catalyst slurry having solid catalyst particles suspended in a liquid; filters which separate the hydrocarbons and the catalyst slurry; and a gas-liquid separator which separates the liquid hydrocarbons flowing out of the filter into gas hydrocarbons and liquid hydrocarbons.2012-01-05
20120003128COATED CERAMIC PART - A device including a first part having a substrate made of a material based on a silicon compound, a coating made of a coating material having a ceramic oxide, a transition layer having silica extending between the substrate and the coating, the transition layer exhibiting a thickness of less than 10 μm, and a first shrink ring and/or a layer made of a compliant material having an alloy with at least two materials selected from silver, gold and palladium, the coating defining at least a portion of the interface between the first part, and the first shrink ring and/or the layer made of a compliant material.2012-01-05
20120003129PIPETTE FOR A PIPETTE SYSTEM HAVING PIPETTE AND SYRINGE - A pipette for a pipette system comprising a pipette and a syringe. The pipette housing has a longitudinal axis. A syringe to be handled with the pipette is insertable with its fastening portion and plunger head into the pipette housing and is removable or discardable from said pipette housing in the direction of the longitudinal axis of the pipette housing, i.e., axially. The syringe has as cylinder and a plunger with a plunger head which projects out of the end of the cylinder even when the plunger has been completely inserted into the cylinder. A pipette housing comprises an axially accessible plunger gripping device for the plunger head of the syringe. An actuating device for the plunger gripping device is mounted on the plunger displacing device and is axially displaceable with said adjusting device.2012-01-05
20120003130ALUMINA PRODUCTION PROCESS - An improved process for producing alumina from bauxite is disclosed comprising the steps of: 2012-01-05
20120003131INTEGRATED DIESEL PARTICULATE FILTER AND ELECTRIC LOAD BANK - An apparatus for dissipating energy into the exhaust gas of an internal combustion engine includes a container for confining a flow path for exhaust gas from an internal combustion engine where the container has an inlet and an outlet. A porous, electrically conductive mesh is placed in the container such that exhaust gas can flow through the conductive mesh. At least two electrical terminals are in permanent electrical contact with the conductive mesh. An electrical power supply completes an electrical circuit through the conductive mesh with the power supply having two or more electrical outputs electrically connected to an equal number of electrical terminals on the conductive mesh. The apparatus provides a filter, heater, electrical load and silencer.2012-01-05
20120003132Process for catalytic deoxygenation of coal mine methane - Deoxygenation catalyst for coal mine methane, its preparation method and application in catalytic deoxygenation of coal mine methane in oxygen-containing environment. The catalyst comprises a first composition serving as the active content and a second composition serving as the additive. The first composition consists of one or more platinum group noble metals selecting from the group consisting of Pd, Pt, Ru, Rh and Ir. The second composition consists of one or more alkaline metals or alkaline earth metals selected from the group consisting of Na2012-01-05
20120003133Air Pollution Solution to the Problem of Opacity in Coal Fired Power Plant Stack Emissions - A method of controlling air pollution arising from sulphur trioxide and or sulphuric acid in coal combustion gases, combustion gases passing through the demister region of a wet flue gas desulphurisation unit are exposed to a sulphide based reducing agent such as hydrogen sulphide, such that metal catalysts promoting the oxidation of ammonia leading to the formation of nitrosylsulfuric acid are poisoned and so prevented from catalysing the formation and discharge of sulphuric acid in aerosol emissions in stack gases.2012-01-05
20120003134DEACTIVATION RESISTANT PHOTOCATALYSTS - The present disclosure relates to a fluid purification device that has a deactivation resistant photocatalyst having nanocrystallites of less than 14 nanometers (nm) in diameter with at least 200 m2012-01-05
20120003135WATER TREATMENT - Methods of treating water, methods of removing radium from water, methods for controlling the amount of at least one target element removed from water and the amount of at least one target element in a pellet, a pellet and treated water. The method may generally include providing water including a principal ion and a target element, contacting the water with a fluidized bed, the fluidized bed including seed material, and controlling at least one of a type and a size of the seed material to remove principal ion and target element from the water. The target element may include radium. The principal ion may include calcium, magnesium, etc. A pellet may include a seed material, radium carbonate crystals, and calcium carbonate crystals2012-01-05
20120003136Proppants With Carbide And/Or Nitride Phases - The present invention relates to proppants which can be used to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more proppants of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the proppants of the present invention are further disclosed, as well as methods of making the proppants.2012-01-05
20120003137EXTRACTIVE DISTILLATION OF AsF5 AND PF5 USING HF - Arsenic can be an impurity in phosphorous pentafluoride production processes. It is desirable to remove arsenic from phosphorous pentafluoride prior to using of the phosphorous pentafluoride in the production of lithium hexafluorophosphate. The present technology provides methods of removing arsenic from phosphorous pentafluoride by extractive distillation.2012-01-05
20120003138AZEOTROPE-LIKE COMPOSITION OF PF5 AND HF - Provided are azeotropic and azeotrope-like compositions of PF2012-01-05
20120003139METHOD FOR MANUFACTURING POWER STORAGE DEVICE - It is an object to provide a material for an electrode with improved electron conductivity and a power storage device using the material for an electrode. In a process for manufacturing a material for an electrode including a lithium phosphate compound represented by a general formula LiMPO2012-01-05
20120003140METHOD FOR IMPROVING GYPSUM/PHOSPHORIC ACID SLURRY FILTRATION USING CARBOXYMETHYL CELLULOSE - A chemical process to improve the filtration performance for the removal of gypsum from phosphoric acid/gypsum slurry using a filtration aid that is selected from a class of polymers, lower molecular weight anionic polyelectrolytes, which previously have not been used for this application. The polymer is CMC or Carboxymethyl Cellulose, which is a polymerized cellulose ether. CMC is found to be extremely effective for phosphoric acid/gypsum slurry that was produced from igneous phosphate rock. CMC is also available in food grade, which is novel for filtration aids for the production of phosphoric acid which may be used for human or animal feed.2012-01-05
20120003141PROCESS AND APPARATUSES FOR PREPARING ULTRAPURE SILICON - A process for preparing high-purity silicon by thermal decomposition of a silicon compound includes decomposing the silicon compound by mixing with a carrier gas at a temperature at which the silicon compound is thermally decomposed.2012-01-05
20120003142VAPOR-PHASE PROCESS APPARATUS, VAPOR-PHASE PROCESS METHOD, AND SUBSTRATE - A vapor-phase process apparatus and a vapor-phase process method capable of satisfactorily maintaining quality of processes even when different types of processes are performed are obtained. A vapor-phase process apparatus includes a process chamber, gas supply ports serving as a plurality of gas introduction portions, and a gas supply portion (a gas supply member, a pipe, a flow rate control device, a pipe, and a buffer chamber). The process chamber allows flow of a reaction gas therein. The plurality of gas supply ports are formed in a wall surface (upper wall) of the process chamber along a direction of flow of the reaction gas. The gas supply portion can supply a gas into the process chamber at a different flow rate from each of one gas supply port and another gas supply port different from that one gas supply port among the plurality of gas supply ports.2012-01-05
20120003143OXIDATION TREATMENT METHOD AND OXIDATION TREATMENT APPARATUS - An oxidation treatment method of the present invention includes the step of bringing a solution having an ozone concentration of 120 to 500 mg/L into contact with a substance to be treated made of a combustible substance, thereby subjecting the substance to be treated and the surface thereof to an oxidation treatment. An oxidation treatment apparatus of the present invention includes: a dissolving means that dissolves an oxygen-ozone mixed gas in a fluorine-based solvent to form mixed fluid; an undissolved gas removal means that removes an undissolved gas from the mixed fluid to form a solution; and an oxidation treatment means that brings the solution into contact with a substance to be treated made of a combustible substance, thereby subjecting the substance to be treated and the surface thereof to an oxidation treatment.2012-01-05
20120003144BONE TISSUE REGENERATION WITH CALCIFIED SUBSTANCE PRODUCED BY CULTURED CELLS - Disclosed is a material having a higher and direct bone-inducing ability, which is made of a calcified substance produced by a cell. Specifically disclosed is a material for regenerating a bone tissue, which comprises a calcified substance extracted from a cultured cell expressing a calcification capacity. In the material, the cultured cell expressing a calcification capacity may be a mammalian cell. In the material, the calcified substance may be extracted without sintering at a high temperature. Also disclosed is an artificial bone containing the material.2012-01-05
20120003145Process For Recovering Hydrogen And Carbon Dioxide From A Syngas Stream - The present invention provides a process for recovering high purity gaseous hydrogen and high purity gaseous carbon dioxide from a syngas stream by utilizing a hydrogen selective membrane unit and a primary water gas shift reactor in combination with a cryogenic purification unit, a hydrogen recovery unit and a secondary water gas shift reactor or by utilizing a hydrogen membrane/water gas shift reactor in combination with a cryogenic purification unit, a hydrogen recovery unit and a secondary water gas shift reactor. Each of these embodiments may further include a sulfur recovery unit.2012-01-05
20120003146NATURALLY-OCCURRING NANOMATRIX BIOMATERIALS AS CATALYSTS - This disclosure provides systems, methods, and compositions for facilitating hydrogen storage, typically using naturally-occurring nanostructured biomaterials such as diatoms or diatomaceous material in their natural or modified forms to facilitate the hydrogen storage. For example, when the nanostructured biomaterials are in contact with a metal hydride such as a complex or a simple metal hydride, the resulting composition functions a catalytic composition that can reversibly desorb and resorb hydrogen gas in an efficient manner. Examples of modification include, but are not limited to, modification of the nanostructured silica with any number of metals.2012-01-05
20120003147UZM-35 ZEOLITIC COMPOSITION, METHOD OF PREPARATION AND PROCESSES - A new family of crystalline aluminosilicate zeolitic compositions, UZM-35 compositions, has been synthesized. These zeolitic compositions are represented by the empirical formula.2012-01-05
20120003148RADIOIMMUNOTHERAPY AND IMAGING OF TUMOR CELLS THAT EXPRESS VIRAL ANTIGENS - Methods and compositions are provided for treating and imaging a virus-associated cancer, where the methods comprise administering to a subject a radiolabeled binding molecule, wherein the binding molecule binds to a virus antigen expressed by virus-associated cancer cells in the subject.2012-01-05
20120003149NOVEL MONOCLONAL ANTIBODY, AND USE THEREOF - [Theme] To provide a monoclonal antibody against human GPR87. Also, to provide a novel means for diagnosing or treating a malignant tumor.2012-01-05
20120003150THERAPEUTIC RIBONUCLEASES - The present invention relates to the use of ribonucleases (RNases) in the treatment or prevention of disease.2012-01-05
20120003151METHOD FOR EARLY IMAGING OF ATHEROSCLEROSIS - The invention relates to methods of detecting active atherosclerotic plaques associated with blood vessel walls wherein the plaques comprise activated macrophages having accessible binding sites for a ligand. In one embodiment, plaques that block from about 2% to about 60% of the lumen of a blood vessel can be detected.2012-01-05
20120003152COMPOSITIONS AND METHODS OF USE OF TARGETING PEPTIDES FOR DIAGNOSIS AND THERAPY OF HUMAN CANCER - The present invention concerns compositions comprising and methods of identification and use of targeting peptides selective for cancer tissue, particularly prostate or ovarian cancer tissue. The method may comprise identifying endogenous mimeotopes of such peptides, such as GRP78, IL-11Rα and hsp90. Antibodies against such targeting peptides or their mimeotopes may be used for detection, diagnosis and/or staging of prostate or ovarian cancer. In other embodiments, the compositions and methods concern a novel type of gene therapy vector, known as adeno-associated phage (AAP). AAP are of use for targeted delivery of therapeutic agents to particular tissues, organs or cell types, such as prostate or ovarian cancer. In still other embodiments, targeting peptides selective for low-grade lipomas may be used for detection, diagnosis and targeted delivery of therapeutic agents.2012-01-05
20120003153NOVEL INDOLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL AND DIAGNOSTICAL USE - This invention relates to novel indolyl-oxadiazolyl-diazabicyclononane derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.2012-01-05
20120003154ARYLOXYANILIDE DERIVATIVES - The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent of the present invention demonstrates good selective binding to the peripheral benzodiazepine receptor (PBR), in combination with good brain uptake and in vivo kinetics following administration to a subject.2012-01-05
20120003155DENDRIMER BASED NANODEVICES FOR THERAPEUTIC AND IMAGING PURPOSES - A nanodevice composition including N-acetyl cysteine linked to a dendrimer, such as a PAMAM dendrimer or a multiarm PEG polymer, is provided. Also provided is a nanodevice for targeted delivery of a compound to a location in need of treatment. The nanodevice includes a PAMAM dendrimer or multiarm PEG polymer, linked to the compound via a disulfide bond. There is provided a nanodevice composition for localizing and delivering therapeutically active agents, the nanodevice includes a PAMAM dendrimer or multiarm PEG polymer and at least one therapeutically active agent attached to the PAMAM dendrimer or multiarm PEG polymer. A method of site-specific delivery of a therapeutically active agent, by attaching a therapeutically active agent to a PAMAM dendrimer or multiarm PEG polymer using a disulfide bond, administering the PAMAM dendrimer or multiarm PEG polymer to a patient in need of treatment, localizing the dendrimer or multiarm PEG polymer to a site in need of treatment, and releasing the therapeutically active agent at the site in need of treatment.2012-01-05
20120003156METHODS FOR TREATING NEOPLASIA BY INHIBITING LACTATE DEHYDROGENASE AND/OR NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE - The invention provides compositions for the diagnosis or treatment of neoplasias, including lymphomas, leukemias, brain cancers (e. glioblastomas, medulloblastomas), breast cancer, colon cancer, and pancreatic cancer, and methods of use therefor.2012-01-05
20120003157USE OF ANTI-90K MONOCLONAL ANTIBODIES FOR THE PREVENTION AND TREATMENT OF TUMORS AND METASTASES THEREOF - The present invention relates to the use of anti-90K monoclonal antibodies for prevention and treatment of tumors and metastases thereof. In particular, the invention relates to the use of anti-90K monoclonal antibodies able to inhibit the adhesive processes of tumor cells and angiogenesis in tumors such as breast cancer, ovarian cancer, lung cancer, gastrointestinal cancer, melanoma, lymphoma and other tumors overexpressing 90K.2012-01-05
20120003158Biomarkers for Inflammatory Bowel Disease and Methods Using the Same - The present invention provides various biomarkers of inflammatory bowel disease, including biomarkers for Crohn's disease and biomarkers for Ulcerative colitis. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of inflammatory bowel disease, methods for distinguishing between inflammatory bowel diseases, methods of determining predisposition to inflammatory bowel disease, methods of monitoring progression/regression of inflammatory bowel disease, methods of assessing efficacy of compositions for treating inflammatory bowel disease, methods of screening compositions for activity in modulating biomarkers of inflammatory bowel disease, methods of treating inflammatory bowel disease, as well as other methods based on biomarkers of inflammatory bowel disease.2012-01-05
20120003159COMPOSITIONS AND METHODS FOR ENHANCING CONTRAST IN IMAGING - Examples of compositions of liposomes and methods of making the same containing high concentrations of contrast-enhancing agents for computed tomography are provided. Example compositions of such liposomes, when administered to a subject, provide for increased contrast of extended duration, as measured by computed tomography, in the bloodstream and other tissues of the subject. Also provided are example methods for making the liposomes stable, that is, resistant to leakage of the contrast-enhancing agents, including the extrusion of the liposomes at high pressures and at high flow rates per total pore area of the extrusion filters.2012-01-05
20120003160Macrophage-Enhanced MRI (MEMRI) in a Single Imaging Session - Methods for performing macrophage-enhanced MRI, utilizing a macrophage imaging agent, in a single imaging session are provided. The macrophage imaging agent may be an ultrasmall superparamagnetic iron oxide particle. One embodiment includes administering a macrophage imaging agent to the subject during an administration session then allowing a passage of time sufficient for accumulation of the agent in macrophages of the subject. Subsequently, in a single imaging session, a macrophage-enhanced magnetic resonance image is acquired to target macrophages and a different magnetic resonance image is acquired to target physiological phenomenon other than macrophages. Additional embodiments provide methods wherein the acquisition of a different magnetic resonance image is achieved by vascular-enhanced MRI protocols or perfusion-enhanced MRI protocols, or combinations thereof. Further embodiments provide methods for utilizing acquired images in assessment of treatment of disease.2012-01-05
20120003161USE OF INOSITOL-TRIPYROPHOSPHATE IN TREATING TUMORS AND DISEASES - Inositol-tripyrophosphate is an allosteric effector of hemoglobin due to its ability to cross the plasma membrane of red blood cells and deliver oxygen to solid tumors, by lowering the oxygen affinity of the hemoglobin of red blood cells. The present invention is directed to the use of inositol-tripyrophosphate to reduce hemoglobin's affinity for oxygen in circulating red blood cells. The present invention is further directed to the use of inositol-tripyrophosphate to inhibit angiogenesis and enhance radiation sensitivity of hypoxic tumors. The present invention is further directed to the use of inositol-tripyrophosphate to enhance PO2012-01-05
20120003162Methods of Preparing Non-Alcohol Bioactive Esential Oil Mouth Rinses - The invention relates generally to liquids such as mouth rinses for the prevention and elimination of bad breath as well as for the reduction of oral microorganisms responsible for the development of dental plaque and tooth decay. In particular, the present invention relates to a method of preparing non-alcohol or reduced alcohol mouth rinses effective at preventing the above-mentioned problems.2012-01-05
20120003163Non-Alchohol Bioactive Essential Oil Mouth Rinses - The invention relates generally to mouth rinses for the prevention and elimination of bad breath as well as for the reduction of oral microorganisms responsible for the development of dental plaque and tooth decay. In particular, the present invention relates to a non-alcohol or reduced alcohol mouth rinses effective at preventing the above-mentioned problems.2012-01-05
20120003164COSMETIC OR DERMATOLOGICAL COMPOSITION CONTAINING AN ACTIVE AGENT WHICH STIMULATES SYNTHESIS OF THE PROTEIN HSP 32 IN THE SKIN - A dermatological or cosmetological composition for an external topical administration, included together with pharmaceutically and/or cosmetologically acceptable excipients: at least one UVA-stabilizing and/or UVB-stabilizing screening agent, at least one compound capable of activating the endogenous synthesis of Heat Shock Protein (HSP) 32 or a functional peptide fragment of such a protein, and forskolin or any extract containing it.2012-01-05
20120003165Ester Gels, Methods of Manufacture, and Uses Thereof - Gels of isopropyl esters of fatty alcohols that include a dimethyl/methylhydrogensiloxane copolymer, a silanol-terminated PDMS or an ethenyl-terminated PDMS, and a hydride functional siloxane. Also provided are methods for making the gels and articles containing them.2012-01-05
20120003166COSMETIC COMPOSITION FOR NAILS AND THE USE OF AN ISOSORBIDE DERIVATIVE - A cosmetic composition for nails containing a plasticizer of natural origin, a derivative of sorbitol, and the use of isosorbide diester as a plasticizer in cosmetic compositions for nails.2012-01-05
20120003167COSMETIC COMPOSITION COMPRISING SILOXANE RESINS AND AT LEAST ONE PHENYL SILICONE OIL - The invention relates to a composition containing the following components in a physiologically acceptable medium, namely: a) a siloxane resin comprising at least 80 mole % of units (i) (R′2012-01-05
20120003168Topical Lightening Composition and Uses Thereof - The disclosure relates to novel topical lightening compositions a skin depigmenting agent and a vehicle. There is provided a topical lightening composition comprising a substituted-4-oxobutanoic acid, ester, or amide tyrosinase inhibitor, and a vehicle. The depigmenting agents of this disclosure can be used as such or as a pharmaceutically acceptable salt including conventional non-toxic salts which include a metal salt or an alkaline earth metal salt, an ammonium salt, or an organic base salt. The depigmenting agents of this disclosure can be incorporated into any cosmetically-, dermatologically-, or cosmeticatically-acceptable vehicle or carrier normally used for topical application. The compositions and methods of the disclosure are effective to lighten skin, hair, lips, and/or nails.2012-01-05
20120003169COMPOSITION COMPRISING A POLYOL, A POLYVINYL ALCOHOL AND A OIL-SOLUBLE POLAR MODIFIED POLYMER - The invention relates to a composition comprising a oil-soluble polar modified polymer, a polyvinyl alcohol and a hyperbranched polyol.2012-01-05
20120003170CHEMICALLY STABLE INGREDIENTS AS LEMON ODORANT - The present invention discloses certain nitrile compounds that are chemically stable and are useful as a lemon odorant or to impart a lemon odor to various consumer articles. The invention also relates to the compositions and articles that contain such compounds as well to the use of the compounds in a method of imparting a lemon odor to the compositions and articles.2012-01-05
20120003171VOLUMIZING SMUDGE RESISTANT MASCARA COMPOSITION - The present invention is directed to a volumizing eye make-up composition having a creamy texture and feel containing: (a) at least one alkyl ethoxylated polymer wax; (b) at least one polar modified polymer; (c) water; (d) optionally, at least one non-volatile solvent; (e) optionally, at least one volatile solvent; and (f) at least one colorant, and wherein the composition preferably has a solids content of less than 40% by weight, based on the weight of the composition.2012-01-05
20120003172USE OF VOLATILE LINEAR ALKANE(S) AND LIQUID FATTY ESTER(S) IN AN ANHYDROUS MEDIUM FOR THE TREATMENT OF KERATIN FIBRES, AND AN ANHYDROUS COMPOSITION BASED ON VOLATILE LINEAR ALKANE(S), LIQUID FATTY ESTER(S) AND PARTICULAR OIL(S) - Use, for the cosmetic treatment of keratin fibres such as the hair, of at least one volatile linear alkane and at least one liquid fatty ester of C2012-01-05
20120003173LOW CHLORINE ODOR CONTROL COMPOSITIONS - An odor control composition includes (a) at least one fragrance and (b) a halo active aromatic sulfonamide compound of Formula (I):2012-01-05
20120003174OTIC COMPOSITIONS FOR THE TREATMENT OF INFECTIONS OF THE INTERNAL AND EXTERNAL EAR IN MAMMALS - Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.2012-01-05
20120003175THERAPEUTIC USES OF MASTIC GUM FRACTIONS - The invention relates to pharmaceutical compositions and formulations comprising polymeric myrcene. More particularly, the invention relates to compositions comprising an isolated fraction of polymeric myrcene in a hydrophobic carrier and formulations which maintain the biological activity of the active polymer.2012-01-05
20120003176HYDROGEL-FORMING COMPOSITION COMPRISING NATURAL AND SYNTHETIC SEGMENTS - A hydrogel composition is formed from a natural polymer derivative having a plurality of cross-linkable units depending therefrom, and a synthetic polymer derivative having a plurality of cross-linkable units depending therefrom, said natural and synthetic polymer derivatives having hydrolysable units disposed between the polymer backbone of said derivative and at least some of said cross-linkable units. The use of a combination of natural and synthetic polymers provides for biodegradability of the hydrogel, along with mechanical properties such as strength and elasticity.2012-01-05
20120003177CURCUMIN-CONTAINING POLYMERS AND WATER-SOLUBLE CURCUMIN DERIVATIVES AS PRODRUGS OF PRODRUG CARRIERS - Curcumin, a polyphenol extracted from the rhizome turmeric, has been polymerized to produce a polymer material having a backbone of one or more repeating structural units, at least one of which comprises a curcumin monomer residue. These curcumin-containing polymers have a wide range of pharmacological activities, including, among others antitumor, antioxidant, antiinflammatory, antithrombotic and antibacterial activities. Certain species of these polymers have exhibited remarkable antitumor activity. Water-soluble curcumin derivatives and their use as prodrugs and prodrug carriers are also disclosed.2012-01-05
20120003178EVALUATING THE THERAPEUTIC POTENTIAL OF A GLUCAN - Provided herein are methods for predicting the response of a subject to administration of a glucan prior to said administration, comprising in one embodiment: isolating at least one cell from the subject, wherein the cell is capable of being stimulated by the glucan; contacting the at least one cell with the glucan and incubating for a period of time and under suitable conditions sufficient to stimulate the cell(s) thereby inducing a change in the level of expression, activity and/or secretion of one or more biomarkers from the cell(s); and determining the level of expression and/or secretion of the at least biomarker, wherein the level of expression, activity and/or secretion is predictive of the response of the subject to administration of the glucan.2012-01-05
20120003179ANTI-CTLA-4 AND CPG-MOTIF-CONTAINING SYNTHETIC OLIGODEOXYNUCLEOTIDE COMBINATION THERAPY FOR CANCER TREATMENT - The invention relates to administration of an anti-CTLA-4 antibody, particularly human antibodies to human CTLA-4, such as those having amino acid sequences of antibodies 3.1.1, 4.1.1, 4.8.1, 4.10.2, 4.13.1, 4.14.3, 6.1.1, 11.2.1, 11.6.1, 11.7.1, 12.3.1.1, 12.9.1.1, and MDX-010, in combination with an immunostimulatory nucleotide, i.e., CpG ODN PF3512676, for treatment of cancer. The invention relates to administering a combination of an anti-CTLA-4 antibody and CpG ODN PF3512676 as neoadjuvant, adjuvant, first-line, second-line, and third-line therapy of cancer, whether localized or metastasized, and at any point(s) along the disease continuum (e.g., at any stage of the cancer).2012-01-05
20120003180PERLECAN DOMAIN V PROTECTS, REPAIRS AND RESTORES ISCHEMIC BRAIN STROKE INJURY AND MOTOR FUNCTION - The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for the treatment of stroke, TBI or SCI. DV is also referred to as endorepellin in the art. This application also provides compositions and combination therapies for the treatment of stroke, TCI and/or SCI. Another aspect of the invention provides methods of restoring motor function in subjects having neurological damage arising from a stroke, TBI or SCI.2012-01-05
20120003181Novel Retinoid Inducible Factor and Uses Thereof - The present invention describes a novel retinoid-responsive nucleic acid, and a novel protein. Further, the invention describes the use of such a nucleic acid or protein in various diseases, and for the treatment, the diagnosis and prognosis of various diseases, and also for a method for the prognosis of responsiveness to retinoids.2012-01-05
20120003182GENETIC SEVERITY MARKERS IN MULTIPLE SCLEROSIS - The present invention relates to the use of SNPs in predicting susceptibility and/or severity of Multiple Sclerosis in an individual. The SNPs are located in the introns of the glycosylation enzymes MGAT5 and XYLT1, 3′ of HIF1AN, within introns of MEGF11. FGF14, PDE9A and CDH13 and within desert regions of 4q34 and 17p13.2012-01-05
20120003183ADDITION SALTS OF TROMETHAMINE WITH AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS - The present disclosure is directed to novel crystalline addition salts of (i) tromethamine with (ii) an azabiphenylaminobenzoic acid derivatives of formula (I), pharmaceutically acceptable solvates thereof, pharmaceutical combinations thereof, and methods of treatment.2012-01-05
20120003184SODIUM SALT OF 5-CYCLOPROPYL-2-BENZOIC ACID AS DHODH INHIBITOR - The present disclosure is directed to the sodium salt of 5-cyclopropyl-2-{[2-(2,6-difluorophenyl)pyrimidin-5-yl]amino}benzoic acid, pharmaceutically acceptable solvates thereof, pharmaceutical combinations thereof, and methods of treatment.2012-01-05
20120003185BONE-LIKE PROSTHETIC IMPLANTS - A prosthetic implant comprising a biocompatible three-dimensional scaffold and at least two cell types selected from the group consisting of osteoblasts, osteoclasts, and endothelial cells or progenitors thereof.2012-01-05
20120003186METHOD FOR DEDIFFERENTIATING ADIPOSE TISSUE STROMAL CELLS - A method for dedifferentiating adipose tissue stromal cells (ATSC) is provided. When the ATSC is treated under hypoxia condition and with a 4-(3,4-Dihydroxy-phenyl)-derivative (DHP-derivative), expression of stemness genes, cellular growth-related genes and cellular mobility-related genes increase, and expression of histone and DNA methylation-related genes decrease so that cell proliferation increases and pluripotency for differentiating into adipocytes, osteocytes, myocytes, beta cells and cartilage cells is acquired. When the dedifferentiated ATSC is implanted into animal model with spinal cord injury and diabetic animal model, effects of nerve regeneration and increased blood surge level are confirmed. As a result, the method for dedifferentiating the ATSC can be effectively used in the stem cell research, tissue regeneration and development of cytotherapeutic medicines.2012-01-05
20120003187BIOLOGICAL MEDIUM FOR PRESERVING A PREPARATION OF INSULIN-SECRETING CELLS - A method for preserving a preparation of insulin-secreting cells includes the step of placing the preparation of insulin-secreting cells in contact with a biological medium, the biological medium including a nutritive product including albumin, and further includes a peptone or a mixture of peptones in sufficient quantity to preserve the insulin-secreting cells.2012-01-05
20120003188Compositions and Methods of Using Living and Non-Living Bioactive Devices with Components Derived from Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro - The invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries.2012-01-05
20120003189Materials and Methods to Enhance Hematopoietic Stem Cells Engraftment Procedures - This disclosure is directed to the methods of enhancing hematopoietic stem cells (HSPC) and progenitor cell (HSPC) engraftment procedure. Treatment in vivo of a HSPC donor with compounds that reduce PGE2012-01-05
20120003190LATERAL VENTRICLE CELL COMPOSITIONS AND USE FOR TREATING NEURAL DEGENERATIVE DISEASES - A pluripotent stem cell isolated from the lateral ventrical of the brain or choroid plexus is provided. Compositions and methods of isolating and using the cell also is provided.2012-01-05
20120003191VALPROIC ACID, DERIVATIVES, ANALOGUES, AND COMPOSITIONS INCLUDING SAME AND METHODS FOR THEIR THERAPEUTIC USE - The present disclosure includes methods and compositions for treating any condition or disorder that benefits from activation of the Akt signaling pathway. These methods and compositions involve the use of valproic acid, derivatives, analogs and compositions including the same for treating muscular disorders, such as muscular dystrophy.2012-01-05
20120003192HYDROGEL-FORMING COMPOSITION COMPRISING PROTEIN AND NON-PROTEIN SEGMENTS - A hydrogel-forming composition is formed from a protein polymer derivative having a plurality of cross-linkable units depending therefrom, and a non-protein polymer derivative having a plurality of cross-linkable units depending therefrom, said non-protein polymer derivatives having hydrolysable units disposed between the polymer backbone of said derivative and at least some of said cross-linkable units. The use of a combination of protein and non-protein polymers provides for biodegradability of the hydrogel by hydrolysis of the hydrolysable units and/or enzymatic degradation of the proteins, along with mechanical properties such as strength and elasticity.2012-01-05
20120003193Methods and Apparatus for Manufacturing Plasma Based Plastics and Bioplastics Produced Therefrom - Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.2012-01-05
20120003194IN VITRO MICRO-ORGANS, AND USES RELATED THERETO - Micro-organ cultures which include isolated populations of cells having specific characteristics are described. Salient features of the subject micro-organ cultures include the ability to be maintained in culture for relatively long periods of time, as well as the preservation of an organ microarchitecture which facilitates, for example, cell-cell and cell-matrix interactions analogous to those occurring in the source organ. The micro-organ cultures of the invention can be used in methods for delivering gene products to recipient subjects, for identifying cell proliferative and cell differentiating agents, and identification and isolation of progenitor and stem cells. In addition, the micro-organ cultures of the present invention can be used in methods for identifying inhibitors of cell proliferation, cell differentiation and viral infectivity. In other embodiments, the micro-organ cultures can be used for transplantation.2012-01-05
20120003195IN VITRO MICRO-ORGANS, AND USES RELATED THERETO - Micro-organ cultures which include isolated populations of cells having specific characteristics are described. Salient features of the subject micro-organ cultures include the ability to be maintained in culture for relatively long periods of time, as well as the preservation of an organ microarchitecture which facilitates, for example, cell-cell and cell-matrix interactions analogous to those occurring in the source organ. The micro-organ cultures of the invention can be used in methods for delivering gene products to recipient subjects, for identifying cell proliferative and cell differentiating agents, and identification and isolation of progenitor and stem cells. In addition, the micro-organ cultures of the to present invention can be used in methods for identifying inhibitors of cell proliferation, cell differentiation and viral infectivity. In other embodiments, the micro-organ cultures can be used for transplantation.2012-01-05
20120003196LONG LASTING DRUG FORMULATIONS - The present invention is directed to long-lasting therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a vector which comprises a nucleic acid sequence operably linked to one or more regulatory sequences, wherein the nucleic acid sequence encodes a therapeutic polypeptide, such as erythropoietin or interferon alpha.2012-01-05
20120003197BACILLUS ISOLATES AND METHODS OF THEIR USE TO PROTECT AGAINST PLANT PATHOGENS AND VIRUS TRANSMISSION - Methods of inducing systemic acquired resistance to infection in a plant are provided. The methods comprise applying a composition comprising a 2012-01-05
20120003198Lutein/Zeaxanthin for glare protection - The invention relates to the improvement of visual performance, particularly of visual performance in the darkness, by administration of a colorant that is capable of being incorporated into eye tissue and/or causing yellowing of eye tissue, especially carotenoids, such as lutein and zeaxanthin.2012-01-05
20120003199USE OF SYNTHETIC AND BIOLOGICAL FUNGICIDES IN COMBINATION FOR CONTROLLING HARMFUL FUNGI - The present invention relates to the combined use of synthetic fungicides and biological control agents for controlling harmful fungi. To be more precise, the invention relates to a method for controlling harmful fungi, which comprises at least two treatment blocks, where in at least one treatment block the plants are treated with at least one synthetic fungicide and in at least one treatment block the plants are treated with at least one biological control agent, with the proviso that the last treatment block comprises subjecting the plants to at least one treatment with at least one biological control agent.2012-01-05
20120003200BIOLOGICALLY ACTIVE FOOD SUPPLEMENT - A biologically active food supplement intended to increase the athletes' muscle mass comprises 2012-01-05
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