01st week of 2019 patent applcation highlights part 40 |
Patent application number | Title | Published |
20190003917 | METHOD AND SYSTEMS FOR A VESSEL LEAKAGE TIGHTNESS TEST - A leakage tightness testing system and a method for checking a tightness of a test vessel having a test vessel internal volume and a test vessel thermal inertia characteristic are provided. The leakage tightness testing system includes an external reference vessel coupled in flow communication to the test vessel. The external reference vessel includes an external reference vessel volume that includes an insulative material layer at least partially covering the external reference vessel. The insulative material layer is configured to approximately match a thermal inertia characteristic of the external reference vessel to the thermal inertia characteristic of the test vessel. The leakage tightness testing system also includes a leakage testing device coupled in flow communication to the test vessel and the external reference vessel. The leakage testing device includes a leakage sensor. | 2019-01-03 |
20190003918 | MULTI-LASER GAS LEAKAGE DETECTOR - A system remotely detects a gas leakage from a pipeline in an area. The system detects a gas leakage by determining an absorption or emission of gasses in the area. The gas detection system includes at least two light sources. The lasers can include lasers for detecting absorbance of gasses in the area, lasers for stimulating emission of gasses in the area, and lasers for detecting a pathlength. Absorption is determined based on the relative amplitude difference of emitted and reflected light beams. Emission is determined based on an amount emission stimulated by absorbed lasers. Pathlength is determined calculating time of flight of a light beam. The detection system calculates a concentration of the gasses in the area using the determined absorption and pathlength. The detection system can also generate an image representing a gas leakage in the area. The detection system may be attached to an unmanned aerial vehicle. | 2019-01-03 |
20190003919 | IMAGE PROCESSING DEVICE FOR GAS DETECTION, IMAGE PROCESSING METHOD FOR GAS DETECTION, IMAGE PROCESSING PROGRAM FOR GAS DETECTION, COMPUTER-READABLE RECORDING MEDIUM HAVING IMAGE PROCESSING PROGRAM FOR GAS DETECTION RECORDED THEREON, AND GAS DETECTION SYSTEM - A gas-detection image-processing device includes: a calculation unit that calculates identification values respectively corresponding to a plurality of pixels constituting an infrared image of a monitoring target, the identification values being identification values for identifying a pixel constituting a gas image and a pixel constituting a non-gas image; and an identification unit that, on the basis of the identification values, identifies, in a monitoring image that is generated by using the infrared image, a pixel constituting the gas image and a pixel constituting the non-gas image. | 2019-01-03 |
20190003920 | VISUALIZATION OF MULTI-PIPE INSPECTION RESULTS - Apparatus and methods to visualize pipes of a multi-pipe structure associated with a well site can be implemented in a variety of applications. Responses acquired from signals received in response to transmission of a probe signal from a transmitter operatively disposed within the multi-pipe structure may be processed to determine regions of equivalent metal loss in the pipes. In response to processing the responses, a visualization of the pipes, including defects, may be generated. Additional apparatus, systems, and methods are disclosed. | 2019-01-03 |
20190003921 | CONNECTION END FITTING OF A FLEXIBLE LINE, MEASUREMENT DEVICE AND ASSOCIATED METHOD - An end fitting including an end part of the tubular sheath, an end section of each elongate element, an end vault, and a cover defining a chamber for receiving each end section. The end fitting includes at least one transducer for generating an ultrasonic wave guided in the elongate element, the generation transducer being placed on the elongate element in the receiving chamber, the generation transducer having a volume of less than 200 mm | 2019-01-03 |
20190003922 | DEVICE AND METHOD FOR MOIRE MEASUREMENT OF AN OPTICAL TEST SPECIMEN - An apparatus for the moiré measurement of an optical test object includes a grating arrangement made of a first grating ( | 2019-01-03 |
20190003923 | AUTOMATIC ANALYSIS OF A SET OF OPTICAL FIBERS OF AN OPTICAL CABLE - A device for connecting to an optical cable having a set of optical fibers may include a microscope, an assembly to move the microscope in a continuous manner about an axis substantially parallel to a mating surface of the optical cable, and without moving the device, to bring one or more optical fibers, of the set of optical fibers, within a field of view of the microscope without moving the optical cable, and one or more processors. The device may receive an indication to perform a set of analyses of the set of optical fibers of the optical cable. The device may perform the set of analyses of the set of optical fibers by modifying a position of the microscope of the assembly of the device in a set of directions. The device may output a result of the set of analyses for display. | 2019-01-03 |
20190003924 | ABNORMALITY DIAGNOSTIC METHOD FOR FEED AXIS AND ABNORMALITY DIAGNOSTIC DEVICE FOR THE SAME - It is an object to perform an abnormality diagnosis for a feed axis without additionally adding a sensor or the like. A frequency characteristic of a feed axis and a damage frequency that occurs when the feed axis that has been damaged performs an axis operation are obtained, a frequency where a gain is maximized in the obtained frequency characteristic is calculated, and a feed velocity where the frequency matches the damage frequency is calculated. An axis operation is performed on the feed axis with the calculated feed velocity, and a frequency analysis is performed on servo information regarding a control of a servo motor during the axis operation. Then, the presence and absence of a peak of the damage frequency is confirmed from a result of the frequency analysis, and when the peak is present, it is determined that it is abnormal. | 2019-01-03 |
20190003925 | SYSTEMS AND METHODS FOR INSPECTING BLADES OR VANES IN TURBOMACHINERY - A scanner for inspecting a component is disclosed. The scanner may include a main body having a clamp attachable to the component, a first arm moveably attached to the main body, a first probe attached to the first arm, a first axial actuator in mechanical communication with the first arm, a second arm moveably attached to the main body, a second probe attached to the second arm, a second axial actuator in mechanical communication with the second arm, and a radial actuator in mechanical communication with the first arm and the second arm. | 2019-01-03 |
20190003926 | TEST DEVICE OF UNIVERSAL NAIL/SCREW HOLDING POWER - A test device of universal nail/screw holding power is provided. The device is capable of penetrating a nail/screw into a test piece at any angle and positioning the test piece on which a nail/screw is penetrated at any angle to test the nail/screw holding power. The device includes a base, two opposite supporting plates, two coaxial disks, an upper bearing plate, a lower bearing plate, a side bearing plate, a through groove, a trapezoid slot, and a plurality of trapezoid bolts on the same circumference. When the disk is turned, at least one trapezoid bolt is stretch into the trapezoid slot; when the at least one trapezoid bolt engages with the trapezoid slot and then is tightened up, the at least one trapezoid bolt and the trapezoid slot cooperatively limit the turn of the disk. | 2019-01-03 |
20190003927 | MONITORING DEVICE, MONITORING METHOD, AND PROGRAM - Among a plurality of sensors that detect a state of a control subject, a relationship fluctuation level between a magnitude of a signal output by a subject sensor and a magnitude of a signal output by another related sensor is calculated for each subject sensor and related sensor combination. Moreover, the subject sensor and related sensor combinations for which a value of the relationship fluctuation level is a predetermined value or more are identified, and a respective number of appearances of the subject sensor and the related sensor included in the identified combinations thereof is calculated. | 2019-01-03 |
20190003928 | Diagnostic Device and Diagnostic Method for Rotary Machine - A rotary machine diagnostic device has a current acquisition unit that acquires current from a sensor, which measures the driving current of a rotary machine driving a machine to be driven; a sampling unit that performs sampling of the acquired driving current; a frequency range conversion unit that converts data concerning the time range subjected to sampling into a frequency range; a sideband detection unit that sets the driving current as a carrier wave in the frequency range, and detects, as a sideband, the spectrum appearing on each side of the carrier wave subjected to amplitude modulation; and an abnormality detection unit that detects whether or not there are abnormalities in the rotary machine and the machine to be driven on the basis of the difference in frequency between the sideband frequency detected by the sideband detection unit and the frequency of the carrier wave. | 2019-01-03 |
20190003929 | Computer System and Method for Recommending an Operating Mode of an Asset - Disclosed herein are systems, devices, and methods related to assets and asset operating conditions. In particular, examples involve determining health metrics that estimate the operating health of an asset or a part thereof, determining recommended operating modes for assets, analyzing health metrics to determine variables that are associated with high health metrics, and modifying the handling of operating conditions that normally result in triggering of abnormal-condition indicators, among other examples. | 2019-01-03 |
20190003930 | CARTRIDGES FOR SAMPLE PARTITIONING - Cartridges for sample partitioning and methods of making and using the cartridges are provided. The cartridges include a pouch to receive a mated stem-well film and a sealing film covered by a release liner. The stem film and the sealing film can be respectively separated from the well film and sealing film simultaneously by pulling a pull tab. | 2019-01-03 |
20190003931 | SAMPLING DEVICE FOR INTRODUCING INDIVIDUALIZED SEED GRAINS INTO A MEASURING DEVICE, SYSTEM AND METHOD FOR SORTING A PLURALITY OF SEED GRAINS, AND USES THEREOF - The present invention relates to a system ( | 2019-01-03 |
20190003932 | Speed Loop for Take-Off and Return by Single Pipeline Probe - A sample take-off system incorporating a small volume pump with a speed loop for pressurizing excess extracted sample for return into the process stream using a single multi-channel probe for both take-off and return of the excess extracted sample is illustrated and described. | 2019-01-03 |
20190003933 | SEPARATION DEVICES FOR BIOLOGICAL SAMPLES - Devices for physically separating biological samples and methods for separating biological samples are disclosed. An example device may include a vessel for holding a biological sample. The biological sample may include a plurality of cells and a fluid. A filter membrane may be disposed within the vessel and positioned adjacent to an end region of the vessel. An auger member may be disposed within the vessel. The auger member may be designed to drive cells within the biological sample into contact with the filter membrane. | 2019-01-03 |
20190003934 | Clearing Agent and Mounting Media for Microscopy - A clearing agent and mounting solution for microscopy is disclosed comprising at least trichloroethanol and/or derivatives thereof, where the refractive index of the solution is greater than or equal to about 1.3810. Also disclosed are methods of preparing specimens for microscopy. | 2019-01-03 |
20190003935 | FILTRATION DEVICE WITH REMOVABLE PROTECTIVE MEMBER - A cell filtration assembly adapted to capture cells from a biological sample during centrifugation includes a filter support member including a sample well and a filter membrane that spans the sample well. In some cases, the filter support member and/or the filter membrane may be adapted to be sectioned. In some cases, a protective element may be disposed over at least a portion of the filter support member in order to protect the filter support member from tissue processing reagents during processing of the cells captured from the biological sample. | 2019-01-03 |
20190003936 | SYSTEM AND METHOD FOR DESORBING AND DETECTING AN ANALYTE SORBED ON A SOLID PHASE MICROEXTRACTION DEVICE - Disclosed herein is a system for desorbing and detecting an analyte sorbed on a solid phase microextraction (SPME) device. This SPME device The system includes a desorption chamber containing solvent required for desorption of analytes from SPME device; a flow injector in fluid connection with the desorption chamber, the desorption chamber and the flow injector being fluidly connected by at least a flow-insulating fluid connector; a solvent source in fluid connection with the flow injector; and a fluid switch that: in a desorption position, allows the solvent to be sprayed from the flow injector while flow-insulating any desorption solution in the desorption chamber, and in an detecting position, turns off the solvent source while maintaining the fluid connection between the flow injector and the desorption chamber, transferring the desorption solution through the flow-insulating fluid connector to the flow injector as a substantially undiluted plug of liquid. The SPME device can be configured to be various morphologies such as, fibers, blades, thin film membranes and even magnetic particles. When magnetic particles are used an additional holder that contains an embedded magnet which holds a plate with a well to hold said magnetic particles is added to the system. | 2019-01-03 |
20190003937 | ENZYMATIC SAMPLE PURIFICATION - An enzymatic purification method involves the introduction of a sample comprising a target analyte and amino acids into a porous matrix of a reaction chamber. The reaction chamber includes first pores and second pores. The first pores contain polypeptide synthesis enzymes that react with the amino acids to form polypeptides. First pores having a first size to be accessible by amino acids but inaccessible by the subsequently formed polypeptides. The second pores have a second size greater than the first size, are in contact with the first pores and form a series extending from within the reaction chamber to a waste chamber. The formed polypeptides are migrated through the series of second pores to the waste chamber. The target analyte of the sample is extracted from the reaction chamber. | 2019-01-03 |
20190003938 | PRINTING OF FSL CONSTRUCTS - Method of localizing cells to at least one discrete area on a surface of a substrate by propelling droplets of an aqueous dispersion of a synthetic construct of the structure F-S-L from a plurality of orifices located in a print head of an inkjet printer onto the surface. In the structure F-S-L, F is a functional moiety capable of associating with the cells by direct or indirect non-covalent interaction with biotin or an epitope of an antigen presented at the surface of the cells, S is a spacer selected to provide a construct that is dispersible in water at a temperature of 25° C. in the absence of organic solvents or detergents, and L is a diacyl- or dialkyl lipid. | 2019-01-03 |
20190003939 | THAWING METHODS AND APPARATUS - The invention provides a method of thawing a sample comprised in a container, the method comprising the steps of: a) calculating an agitation program as a function of either or both of the sample volume and the type of the container, and the ice fraction in the sample, and optionally the thermal conductivity of the sample container; b) agitating said sample according to the program to agitate at least one region of the sample; and c) changing the agitation program applied to at least one region of the sample in response to changes in the sample volume and/or sample ice fraction. The invention further provides a method of reducing shearing to cells during a method of agitation, and methods for thawing a sample wherein a sample container is differentially heated. An apparatus for use in the methods is also provided, as is an apparatus for thawing and/or cooling a sample which comprises a resilient vessel wall. | 2019-01-03 |
20190003940 | PHOTODEGRADABLE SAMPLE COLLECTION SYSTEM AND METHOD - A method includes providing a biological sample, providing a sample collection device, wherein the sample collection device includes a sample binding surface including a photodegradable polymer configured to bind the biological sample, contacting the biological sample with the sample binding surface of the sample collection device, and irradiating the sample binding surface and the bound biological sample using light emitted from a light source to initiate degradation of the photodegradable polymer of the sample binding surface to cause release of the biological sample. | 2019-01-03 |
20190003941 | DEVICES AND METHODS FOR TENSION MEASUREMENTS AND APPLICATIONS OF SAME - A device for measuring a tension of a bio-object construct as it is being stretched that includes a microscope, a holding member for accommodating the bio-object, and a probe. The microscope includes a condenser, an objective and a stage positioned therebetween. The stage is movable along a horizontal plane. The holding member is fixable on the stage. The probe has a first end attached to the condenser, and a second end placed in the holding member. The stage operably moves such that the bio-object construct moves toward the second end of the probe and contacts with the second end of the probe, thereby causing a displacement of the second end of the probe and a displacement of the bio-object construct, which are used to measure the tension of the bio-object construct. | 2019-01-03 |
20190003942 | MOBILE BIPENDULUM IMPACT TEST MACHINE - A bipendulum impact test machine for imparting impact damage includes a frame of beams where a weighted sled swings from a pair of links extending from a carriage. The carriage and sled are vertically adjustable along a set of vertical shafts of the frame. The sled is permanently horizontally oriented and parallel with the carriage. Interchangeable impact tips are removably and adjustably engaged with the sled. The impact tips have a variety of shapes in order to simulate different impact scenarios. The device is mobile and capable of imparting impact damage to large aircraft parts even in an installed condition. | 2019-01-03 |
20190003943 | FLOOR JOIST - A floor joist including a first piece of lumber including a first set of fingers and a first set of grooves is provided. A second piece of lumber including a second set of fingers and a second set of grooves is also provided. A finger joint is formed by a combination of the first second of fingers with the second set of grooves and a combination of the second set of fingers with the first set of grooves. A first set of pockets are formed between the combination of the first second of fingers with the second set of grooves, and a second set of pockets are formed between the combination of the second set of fingers with the first set of grooves. | 2019-01-03 |
20190003944 | METHOD FOR DEFINING THRESHOLD STRESS CURVES UTILIZED IN FATIGUE AND DAMAGE TOLERANCE ANALYSIS - A method for defining a threshold stress curve utilized in fatigue and/or damage tolerance analysis, the method including conducting a direct test method on a plurality of specimens with a notch to generate raw data, the notch in each of the specimens having a notch dimension; determining a plurality of analyzed data points based upon the raw data; determining a regression line based upon the plurality of data points, the regression line including an exponential portion and a power law portion; and connecting the exponential portion and the power law portion of the regression line to form a threshold stress curve based on the regression line. | 2019-01-03 |
20190003945 | ACCELERATED PAVEMENT TESTING - A method of testing pavement includes repeatedly simulating wheel loading on the pavement by repeatedly applying a plurality of discreet forces with a downwards component, in series and one after the other, to an upper surface of a test strip of the pavement thereby to simulate a load exerted by a travelling wheel and hence subjecting the pavement to accelerated testing. Also provided is an accelerated pavement testing device ( | 2019-01-03 |
20190003946 | Testing and/or Inspection Device - A testing and/or inspection device for determining the resistance of objects to abrasion, impacts and/or scratches, including an adaptive retaining device for the object to be inspected, at least one means for placing an active test object proximate to the object to be inspected, and a device for moving the active test object hitting the object to be inspected, as well as a control, inspection and/or display device for controlling and/or inspecting the speed and force at which the active test object contacts the object to be inspected. The device moves the active test object against, on and/or along the object to be inspected, with a carrier device for the active test object, which may be loaded with a weight, and is equipped with a fluid-activated drive, with a non-rotatable thrusting and/or towing device, which is actuated by a control and/or regulating unit and/or can be connected thereto. | 2019-01-03 |
20190003947 | Temperature compensated density viscosity sensor having a resonant sensing element - A fluid density measurement device ( | 2019-01-03 |
20190003948 | DEVICES AND METHODS FOR DETERMINING THE DENSITY OF INSULATION - The present disclosure relates to devices and methods for determining the density of insulation (e.g., in a cavity). For example, one aspect of the disclosure is a device that includes a probe, an actuator, a sensor, and a control system. The control system is configured to cause the actuator to oscillate the probe. The sensor is configured to generate a signal that represents the density of insulation. Another aspect of the disclosure relates to a method for determining the density of insulation. The method includes placing a probe into contact with the insulation, causing, via an actuator, the probe to oscillate while in contact with the insulation, and generating, via a sensor, a signal that represents the density of insulation. | 2019-01-03 |
20190003949 | TEST APPARATUS FOR ESTIMATING LIQUID DROPLET - A method is for determining information about liquid droplet fallout during operation of a gas-liquid flare apparatus. The method includes disposing a plurality of tiles in a spaced apart fashion over a monitoring area. A gas hydrocarbon fuel is injected into the gas-liquid flare apparatus to create a combustible flow, and a test fluid is injected into the gas-liquid flare apparatus such that the test fluid is dispersed into the combustible flow. The combustible flow is combusted in in the gas-liquid flare apparatus, resulting in fallout of liquid droplets of the test fluid onto the plurality of tiles. Images of the liquid droplets on the plurality of tiles are analyzed so as to determine the information about liquid droplet fallout in the monitoring area, using a computer. The information about liquid droplet fallout may be used to estimate combustion inefficiency of the gas-liquid flare apparatus. | 2019-01-03 |
20190003950 | SYSTEM AND METHOD OF SENSOR RECONDITIONING IN AN EXHAUST AFTERTREATMENT SYSTEM - A system includes: an exhaust aftertreatment system that includes a particulate matter sensor that includes a heating element configured to selectively provide heat to the particulate matter sensor; and a controller programmed to: receive particulate matter data indicating a state of the particulate matter sensor; determine that the particulate matter sensor is in a full state based on the particulate matter data; and activate the heating element to: (i) a first temperature for a first period of time, the first temperature being sufficient to burn off water or ammonia; (ii) a second temperature for a second period of time immediately after the first period of time, the second temperature being greater than the first temperature and being sufficient to burn off urea, biuret, or melamine; and (iii) a third temperature for a third period of time immediately after the second period of time, the third temperature being greater than the second temperature and being sufficient to burn off carbon. | 2019-01-03 |
20190003951 | METHOD FOR CALIBRATING BIOLOGICAL PARTICLE COUNTER AND CALIBRATION DEVICE OF BIOLOGICAL PARTICLE COUNTER - The biological particle counter has a first circuit configured to generate a first signal corresponding to fluorescence from the biological particle in response to irradiated light. A measurement value obtainer is configured to obtain, from the biological particle counter, a voltage value of the first signal for a calibration particle obtained in such a manner that a fluorescence agent infiltrates into a surface of a polystyrene particle. A circuit adjuster is configured to use reference data indicating a correspondence relation between a fluorescence agent parameter value correlated to the content of the fluorescence agent and a reference voltage value of the first signal corresponding to the fluorescence agent parameter value, thereby specifying the reference voltage value of the first signal corresponding to the fluorescence agent parameter value for the calibration particle. The first circuit is adjusted such that the voltage value of the first signal for the calibration particle reaches the reference voltage value. | 2019-01-03 |
20190003952 | Particle Detection Methods and Systems for Practicing Same - Aspects of the present disclosure include methods for detecting events in a flow cytometer. Also provided are methods of detecting cells in a flow cytometer. Other aspects of the present disclosure include methods for determining a level of contamination in a flow cell. Computer-readable media and systems, e.g., for practicing the methods summarized above, are also provided. | 2019-01-03 |
20190003953 | CELL DETECTION METHOD - Provided is a cell detection method which makes it possible to effectively and accurately perform gene analysis only on target cells. The cell detection method includes a sorting step of obtaining first information derived from cells in a sample solution by using a flow cytometry method and sorting target cells into a container having arrays of wells each having an opening based on the first information, an imaging step of imaging the cells sorted into the container, and a determination step of obtaining second information derived from cells based on the image of the cells captured by the imaging step and determining cells to be analyzed from the sorted cells. | 2019-01-03 |
20190003954 | SYSTEM FOR MONITORING AND CONTROLLING EQUIPMENT LIFE DUE TO CORROSION DEGRADATION - A corrosion maintenance scheduling and implementation system and method measure one or more characteristics of corrosion in equipment before and after implementation of a corrosion remediation action, determine one or more of a change in the one or more characteristics of the corrosion between before and after implementation of the corrosion remediation action, one or more historical operational characteristics of the equipment, or one or more forthcoming operational characteristics of the equipment, and modify a schedule of the corrosion remediation action for the equipment based on one or more of the one or more characteristics of corrosion that are measured, the change in the one or more characteristics of the corrosion, the one or more historical operational characteristics of the equipment, and/or the one or more forthcoming operational characteristics of the equipment. | 2019-01-03 |
20190003955 | METHOD AND APPARATUS FOR DISCRIMINATING BETWEEN BLOODSTAINS, AND COMPUTER PROGRAM FOR EXECUTING THE METHOD - Provided is a method of discriminating between bloodstains, the method including obtaining a captured image of an analysis target; analyzing the captured image and extracting a scattering image of a plurality of bloodstains in the analysis target; estimating a scattering angle of the scattering image; and determining the plurality of bloodstains to be an impact spatter bloodstain if the scattering angle is greater than a preset reference angle, and determining the plurality of bloodstains to be a cessation cast-off bloodstain if the scattering angle is less than the reference angle. | 2019-01-03 |
20190003956 | CONTRAST-AMPLIFYING CARRIERS USING A TWO-DIMENSIONAL MATERIAL - A contrast-amplifying carrier for observing a sample, includes a transparent substrate bearing at least one absorbent coating suitable for behaving as an antireflection coating when it is illuminated at normal incidence at an illumination wavelength λ through the substrate and when the face of the coating opposite the substrate is in contact with a medium referred to as a transparent ambient medium, the refractive index n | 2019-01-03 |
20190003957 | METHOD FOR THERMAL CONTROL DURING SURFACE PLASMON RESONANCE ANALYSIS - Disclosed is an SPR sensor which includes a thermally controlled biosensor. Additionally, the current disclosure describes SPR techniques which include the step of heating the SPR sensor to temperatures greater than ambient temperature. | 2019-01-03 |
20190003958 | ACOUSTIC PROBE AND ACOUSTIC APPARATUS - An acoustic probe includes a plurality of transducers that receives acoustic waves and a supporting body including a supporting portion having a symmetrical concave surface, such as a spherical cap surface, which supports the transducers in a spiral array. The supporting position R at which the supporting portion supports the transducers is given as R(r | 2019-01-03 |
20190003959 | BLIND SEPARATION BASED HIGH ACCURACY PERSPECTIVE DETECTION METHOD FOR MULTILAYER COMPLEX STRUCTURE MATERIAL - The present disclosure discloses a blind separation based high accuracy perspective detection method for a multilayer complex structure material. The method is achieved through blind separation of single channel periodic signals and frequency modulation interference of laser wave numbers. In this method, time series interference images captured by a photodetector are subjected to zero mean normalization; a vector Θ of amplitude, frequency and phase field, which is to be solved and reflects characteristics of each interface in the multilayer complex-structure material, is created and is solved using a mathematical optimization method; a phase field distribution of the vector Θ is finally extracted and is subjected to phase unwrapping, to realize high accuracy detection on an internal distribution of the multilayer complex structure material. The present disclosure has advantages that limitation on a Nyquist depth measurement resolution caused by a limited laser wave number frequency sweep range is overcome, and high accuracy distribution conditions of each interface layer in the multilayer complex-structure material can be acquired. | 2019-01-03 |
20190003960 | METHODS AND APPARATUS FOR POLARIZING RETICLE INSPECTION - Disclosed are methods and apparatus for measuring and controlling polarization for inspection of a semiconductor sample. The method includes (i) setting up an inspection system in a specific mode of operation, (ii) incrementing a first waveplate of the system through a plurality of rotations while keeping a second waveplate of the system static, (iii) measuring an intensity signal from non-patterned areas of the sample for each rotation of the first waveplate, (iv) incrementing the second waveplate through a plurality of rotations while keeping the first waveplate static (v) measuring an intensity signal from non-patterned areas of the sample for each rotation of the second waveplate, (vi) generating a model of a plurality of polarization and waveplate parameters for the system to simulate the intensity signals that were measured for each rotation of the first and/or second waveplate, and (vii) determining the polarization and waveplate parameters for the system based on the model and a polarization state on photomask plane based on the polarization and waveplate parameters. | 2019-01-03 |
20190003961 | Automatic Titration Device - A titration system is disclosed for determining content of an analyte in a sample. The titration system comprises: a controller; a reaction vessel; a titration vessel and an indicator vessel in fluid communication with the reaction vessel; a spectroscopy unit; a sensor for outputting a signal to the controller based on a force exerted by the reaction vessel on the sensor. The controller executes a stored program to: (i) perform titration by delivering to the reaction vessel a first mass of a first fluid comprising the sample, a second mass of a second fluid comprising indicator, and a third mass of a third fluid comprising titrant; (ii) detect color change in the mixture in the reaction vessel based on a signal from the spectroscopy unit and stop titration; and (iii) calculate content of the analyte in the sample based on the first mass, the second mass, and the third mass. | 2019-01-03 |
20190003962 | UV SOLID STATE DETECTION AND METHODS THEREFOR - Devices, systems and methods for detecting molecules in a solid state using UV lights in a dry condition are provided. Interaction between a plurality of molecules, a conformational change of a molecule, a size difference between a plurality of molecules and a presence of a molecule can be detected in a dry environment by measuring a light absorption in at least one of light transmission mode and light reflection mode. In a preferred embodiment, the measurement of a light absorption is performed at a wavelength of ultraviolet light between 260 nm and 285 nm. | 2019-01-03 |
20190003963 | NONDESTRUCTIVE MEASUREMENT APPARATUS - A nondestructive measurement apparatus includes a casing including a grip portion capable of being held in hand and a measurement portion having a ring shaped abutting portion to be abutted to a measurement target such as fruit or vegetable; a light source group including a plurality of light sources arranged to be separated in a circumferential direction in an interior thereof; a ring lens arranged in a ring shape smaller than the abutting portion at an inner portion of the abutting portion, for emitting lights from the light source group to an external of the casing in a ring shape; and a light guide member having one end surface exposed to an inner side of the ring lens and another end surface positioned in the interior of the casing, for emitting lights incident from the one end surface to the external from the another end surface. | 2019-01-03 |
20190003964 | TERAHERTZ FULL POLARIZATION STATE DETECTION SPECTROMETER - The invention relates to a terahertz full polarization state detection spectrometer, which comprises a terahertz wave generator, a polarizer, a polarization splitter, a horizontal terahertz detector and a vertical terahertz detector. The terahertz wave generator generates a terahertz wave and the polarizer optimizes the terahertz wave for purity. The sample to be detected modulates the terahertz wave after purity optimization to obtain the terahertz modulated wave. The terahertz modulated wave is decomposed by the polarization splitter into a horizontal terahertz wave and a vertical terahertz wave whose polarization states are perpendicular to each other. The two terahertz waves are detected by two corresponding terahertz detectors respectively. According to the detected result, the characteristic of the sample is analyzed. The terahertz full polarization state detection spectrometer can quickly and accurately detect all kinds of full polarization state terahertz waves and improve the detection accuracy and efficiency of the sample. | 2019-01-03 |
20190003965 | Absorbance Measuring Device and Method Thereof - A highly-reliable absorbance measuring device that enables highly-accurate measurement of absorbance, and a method thereof are provided. | 2019-01-03 |
20190003966 | Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy - Disclosed are compositions which can mimic DNA and/or RNA in cells of a subject and methods of using them as a substrate in testing efficacy of one or more compositions in reducing and/or preventing radiation, such as ultraviolet (UV) radiation-caused DNA and/or RNA damage of said subject. Also disclosed are systems related to the disclosed methods. | 2019-01-03 |
20190003967 | METHOD FOR CREATING A DIGITAL FLUORESCENT IMAGE - In a method for creating a digital fluorescent image, the light emitted per pixel from an object plane is converted into a sequence of amplitudes, each of which is associated with one specific measurement time, the sequence of amplitudes is auto-correlated in a manner that is delayed by at least one time offset, and a specific correlation amplitude, from which a total amplitude is determined, is formed for each of the time offsets. | 2019-01-03 |
20190003968 | DETECTION CHIP, DETECTION KIT, DETECTION SYSTEM, AND METHOD FOR DETECTING DETECTION TARGET SUBSTANCE - A detection chip includes: a liquid container; and a light-transmitting substrate in which one of two surfaces facing each other faces an inside of the liquid container and an LSPR structure that generates localized surface plasmon resonance by light irradiation is disposed on the other surface of the two surfaces or in a region sandwiched between the one surface and the other surface. | 2019-01-03 |
20190003969 | EMISSION LIFETIME MEASURING METHOD AND APPARATUS FOR MEASURING A MEAN LIFETIME OF ELECTRONICALLY EXCITED STATES - An emission lifetime measuring method, in particular for measuring a mean lifetime of electronically excited states of a sample, comprises the steps of illuminating the sample with at least one excitation light pulse, time-resolved detecting an emission response from the sample and creating a temporal detector response function, and calculating the mean lifetime of the electronically excited states on the basis of the detector response function, wherein the at least one excitation light pulse is shaped such that the sample achieves an equilibrium excited steady-state including a linearly increasing or constant number of the electronically excited states, the detector response function has a linear response function section with a constant slope, and the mean lifetime (τ) of the electronically Diode current and pulse width control excited states is calculated on the basis of at least one of a time position of the linear response function section relative to a reference time of the at least one excitation light pulse and the slope of the linear response function section. Furthermore, an emission lifetime measuring apparatus ( | 2019-01-03 |
20190003970 | MENTHOL DETECTION ON TOBACCO - A method for detecting mentholated tobacco, comprising irradiating tobacco containing menthol and a fluorescent taggant with radiation and observing the tobacco for fluorescence from the taggant. A system and method for detecting and separating mentholated tobacco from non-mentholated tobacco within a product stream is also provided. | 2019-01-03 |
20190003971 | A BIOSENSOR - Disclosed herein is an apparatus comprising: a probe carrier, an optical system and a sensor; wherein the probe carrier comprises a substrate, a first layer and a second layer; wherein the substrate comprises a first surface, a second surface, one or more locations on the first surface configured to be deposit sites for one or more probes; wherein the second surface is at an opposite side of the substrate from the first surface; wherein the first layer is on the first surface of the substrate or is embedded in the substrate under the first surface; wherein the second layer is on the second surface of the substrate or is embedded in the substrate under the second surface; the first and second layers are configured to reduce crosstalk between probes at different locations. | 2019-01-03 |
20190003972 | SYSTEM AND METHOD FOR MEASURING SUN-INDUCED CHLOROPHYLL FLUORESCENCE - A chlorophyll fluorescence measuring system having at least one spectrometer coupled to a data logger. The data logger provides direct control of the spectrometer and includes on-board memory for storage of target and reference spectrum data obtained by the spectrometer. The data logger may be coupled to an external computer that receives and analyzes target and reference spectrum data to determine SIF using a spectral fitting algorithm. The system may include a spectrometer aiming system coupled to and controlled by the data logger. The system may also include one or more environmental sensors configured to measure environment variables. The environmental sensors may be coupled to the data logger for control and data storage. The environmental data may be communicated to the external computer for use in the spectral fitting algorithm. The data logger may be connected to a network for remote monitoring and control. | 2019-01-03 |
20190003973 | NUCLEIC ACID NANOSTRUCTURE BARCODE PROBES - Provided herein are, inter alia, barcode probes comprised of transiently or stably fluorescently labeled nucleic acid nanostructures that are fully addressable and able to be read using standard fluorescent microscope and methods of use thereof including methods of use as detectable labels for probes. | 2019-01-03 |
20190003974 | READER DEVICE FOR LUMINESCENT IMMUNOASSAYS - The present disclosure, among other things, describes a reader system comprising a casing, an optical system, en electromechanical motor system, and one or more digital processors. | 2019-01-03 |
20190003975 | OPTICAL ANALYTE DETECTION SYSTEMS AND METHODS OF USE - Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time. | 2019-01-03 |
20190003976 | Multi-Parameter Water Analysis System with Analysis Application Updateable via a Cloud-Based Data Resource - Multi-parameter water analysis system with a water parameter sensing device configured to wirelessly provide detector data and a smart phone displayable indicator of water analysis test results that are calculated by an analysis application that is updateable via a cloud-based data resource to account for a manufacturing change in indicator chemistry and/or an improvement in test result display. The water parameter sensing device includes an optical sensing apparatus configured to detect light from each of a plurality of indicators for different parameters when the indicator and a chemical parameter are exposed to each other, a processor to process information of the detected light, and wireless communication circuitry for communicating detector data based on the information about the detected light to a remote device. Social networking of water quality data allows sharing to other users. | 2019-01-03 |
20190003977 | ANALYTE SENSING DEVICE - An analyte sensing device and a mobile device incorporating an analyte sensing device are disclosed. One example of an analyte sensing device is disclosed to include a body, a sensor die, and a substantially transparent material positioned such that the sensor die is sandwiched between the body and the substantially transparent material. The sensor die may be in optical communication with the substantially transparent material and in electrical communication with the body. | 2019-01-03 |
20190003978 | PROCESS AND APPARATUS TO DETECT MERCAPTANS IN A CAUSTIC STREAM - The present invention relates to a system to detect mercaptides or sulfides in a caustic stream. More particularly, this invention relates to an on-line analyzer for measuring mercaptides using a color changing reagent to quantify mercaptide or sulfide concentration in a caustic stream. The on-line analyzer which includes a liquid sensor which can provide valuable feedback to an operator for controlling a processing unit for the catalytic oxidation of mercaptides to disulfides in an alkaline environment. | 2019-01-03 |
20190003979 | AUTOMATED AGGLUTINATION ANALYZER WITH CONTOUR COMPARISON - The systems and methods contained herein are directed toward automated analysis of agglutination reactions to determine properties of materials, including viruses and vaccines thereto. Advanced digital imaging and processing techniques are used to determine the presence or absence of viruses or antibodies within a fluid sample. The systems and methods are versatile, and can be used to determine specific properties of biomaterials and viruses, such as titer value, concentration, genotype, phenotype, serotype, vaccine efficacy, viral resistance and other properties of relevance in the medical, research and development fields. Also provided are systems and methods of standardization, repeatability, and data storage and transmittal to reduce errors and subjectivity inherent to conventional assays characterized by human readers. | 2019-01-03 |
20190003980 | LUMINESCENCE MEASUREMENTS IN DIAMOND - A method of and an apparatus for providing an indicator for a diamond as to whether it is natural by testing for the presence or absence of one or more specific markers in the luminescence properties of the diamond, These markers are characterised by luminescence decay time and luminescence wavelength. | 2019-01-03 |
20190003981 | Illumination Source for an Inspection Apparatus, Inspection Apparatus and Inspection Method - Disclosed is an inspection apparatus and associated method for measuring a target structure on a substrate. The inspection apparatus comprises an illumination source for generating measurement radiation; an optical arrangement for focusing the measurement radiation onto said target structure; and a compensatory optical device. The compensatory optical device may comprise an SLM operable to spatially modulate the wavefront of the measurement radiation so as to compensate for a non-uniform manufacturing defect in said optical arrangement. In alternative embodiments, the compensatory optical device may be located in the beam of measurement radiation, or in the beam of pump radiation used to generate high harmonic radiation in a HHG source. Where located in the beam of pump radiation, the compensatory optical device may be used to correct pointing errors, or impart a desired profile or varying illumination pattern in a beam of the measurement radiation. | 2019-01-03 |
20190003982 | Optical Video Measurement System Operable in Multiple Positions - A digital optical video measurement system may include a chassis, a digital imaging system coupled to the chassis, and a light source coupled to the chassis. The light source may be configured to emit light along an optical axis extending in a direction of the digital imaging system. The digital optical video measurement system may also include a table coupled to the chassis. The table may have a first orientation and a second orientation. When the table is in the first orientation, the optical axis may intersect the table. When the table is in the second orientation, the optical axis may be spaced apart from the table. | 2019-01-03 |
20190003983 | APPARATUS AND METHOD FOR NONDESTRUCTIVELY INSPECTING FIBERGLASS AND NONMETALLIC PIPES - A system and method for inspecting a composite material structure for defects includes a) an inspection apparatus having a heating device for heating a surface of the structure, an infrared camera for receiving radiation from the surface in response to heating, a controller configured to generate thermal images from the infrared radiation, b) a training system includes an arrangement for obtaining thermal images from a known composite material sample including a plurality of heating elements positioned to apply heat to an entire surface of the sample, an infrared camera for capturing thermal images of the sample, and a processing system for recording the thermal images in a training database, and c) a computer system coupled to the training system and the inspection apparatus adapted to receive thermal images from the inspection apparatus and detect parameters of defects in the structure using the training database. | 2019-01-03 |
20190003984 | SYSTEMS AND METHODS FOR MONITORING REMOTE INSTALLATIONS - A system for monitoring a petrochemical installation is disclosed. The system can include an optical imaging system comprising an array of optical detectors. The system can comprise processing electronics configured to process image data detected by the optical imaging system. The processing electronics can be configured to detect a target species based at least in part on the processed image data. The processing electronics can further be configured to, based on a detected amount of the target species, transmit an alarm notification to an external computing device over a communications network indicating that the target species has been detected at the petrochemical installation. | 2019-01-03 |
20190003985 | PRINTING RESULT INSPECTION APPARATUS AND METHOD - Provided are a printing result inspection apparatus, a method, and a program capable of determining a printing defect caused by a printing step and a printing paper defect caused by printing paper by reading the printing paper once. A defect determination unit determines whether defected regions extracted from a non-image region are the printing defect or the printing paper defect based on a density change amount and a color, and an image feature amount of a defected region determined as the printing paper defect in the non-image region is stored in paper defect information and is accumulated in a paper defect information storage unit. Next, the defect determination unit determines whether defected regions extracted from image regions are the printing defect or the printing paper defect based on the paper defect information. | 2019-01-03 |
20190003986 | PINHOLE OR HOLE DETECTION DEVICE AND METHOD - A detection device and a detection method for detecting a hole or a pinhole present in a material are provided. The detection device includes: an illumination unit irradiating light at one side of the material; a light receiving unit acquiring an image of the material at the other side of the material to output a detection signal; a detection unit determining whether or not the hole or the pinhole is present in the material using the detection signal; and an illumination control unit dividing the illumination unit into a plurality of regions and controlling the illumination unit to irradiate light having different intensities of illumination for each of the plurality of regions. | 2019-01-03 |
20190003987 | SURFACE DEFECT INSPECTING DEVICE AND METHOD FOR STEEL SHEETS - A surface defect inspecting device for steel sheets includes: an illuminating unit configured to illuminate an imaging target portion on a surface of a steel sheet; first and second diffuse reflection light imaging units arranged at a first angle and at a second angle larger than the first angle with respect to a specular reflection direction of illuminated light reflected from the imaging target portion, respectively, imaging simultaneously reflection light of illuminated light reflected from the imaging target portion; and an image signal processor configured to process first and second diffuse reflection image signals acquired by the first and second diffuse reflection light imaging units, respectively, detecting, as a surface defect portion, a portion for which brightness level is lower than a first predetermined threshold in the first diffuse reflection image signal as well as higher than a second predetermined threshold in the second diffuse reflection image signal. | 2019-01-03 |
20190003988 | System and Method for X-Ray Imaging and Classification of Volume Defects - X-ray imaging and classification of volume defects within a three-dimensional structure includes identifying one or more volume defects within a three-dimensional structure of a sample and acquiring, with a transmission-mode x-ray diffraction imaging tool, one or more coherent diffraction images of the one or more identified volume defects. The process includes classifying the one or more volume defects within a volume of the three-dimensional structure based on the one or more coherent diffraction images, and training an additional optical or electron-based inspection tool based on the one or more classified defects. | 2019-01-03 |
20190003989 | X-RAY INSPECTION APPARATUS AND CORRECTION METHOD FOR X-RAY INSPECTION APPARATUS - To correctly acquire image data of an inspected article by preventing a difference in shade between images caused by a difference in position or sensitivity between sensor elements. An X-ray generation source irradiates an inspection region where an inspected article passes with an X-ray. X-ray detection means receives the X-ray passing through the inspection region using a plurality of sensor elements. Image data generation means generates image data of the inspected article from an output of the X-ray detection means. Incidence condition changing means changes two or more kinds of X-ray incidence conditions common for all of the sensor elements of the X-ray detection means in a state of absence of the inspected article in the inspection region. Correction data generation means acquires correction data that is needed for making a shade of an image uniform for each incidence condition. | 2019-01-03 |
20190003990 | RADIATION DETECTION DEVICE, RADIATION INSPECTION SYSTEM, AND METHOD FOR ADJUSTING RADIATION DETECTION DEVICE - An X-ray detection device is a device that detects X-rays having transmitted through a test subject, and comprises a filter that attenuates some of X-rays, a detector that detects the transmitted X-rays partially attenuated by the filter, a housing, and a holder that has one slit. The detector includes a line sensor, and a line sensor disposed in parallel and close to the line sensor. The holder holds the filter at a predetermined position so that the filter can cover a part of the slit, and the line sensor detects the X-rays attenuated by the filter. | 2019-01-03 |
20190003991 | COMPUTING DEVICE, COMPUTING PROGRAM, X-RAY MEASURING SYSTEM AND X-RAY MEASURING METHOD - A computing device configured to obtain information about a subject using a detection result detected by an X-ray detector which detects an X-ray passing through the subject, which device includes: a unit configured to obtain a detection result of the X-ray detector; a first obtaining unit configured to obtain a complex refractive index of the X-ray after passing through the subject using the detection result; and a second obtaining unit configured to obtain information about the subject in accordance with a correlation between the complex refractive index and a mass absorption coefficient. | 2019-01-03 |
20190003992 | NANO-LEVEL EVALUATION OF KEROGEN-RICH RESERVOIR ROCK - Nano-level evaluation of kerogen-rich reservoir rock is described. A nano-scale beam is formed from kerogen-rich reservoir rock. The nano-scale beam includes reservoir rock and kerogen having polymeric properties. A mechanical experiment is performed on the nano-scale beam. The mechanical experiment is imaged using a scanning electron microscope (SEM) or a transmission electron microscope (TEM). A material parameter of the kerogen in the nano-scale beam is determined based on the mechanical experiment and images obtained responsive to the imaging. | 2019-01-03 |
20190003993 | OPERATION METHOD FOR FLOW SENSOR DEVICE - Method of operating a flow sensor device ( | 2019-01-03 |
20190003994 | A HIGH RESOLUTION, NANOMEMBRANE-BASED, THERMAL DIFFUSIVITY BIOSENSOR FOR LIVING CELLS - A method for measuring thermal diffusivity/conductivity of a microscale sample includes placing a metallic disk atop the sample, and disposing a nanomembrane over the sample and over the metallic disk so that the nanomembrane, so that the metallic disk, the nanomembrane and the sample are in thermal equilibrium with one another. A laser beam is directed to fall onto the nanomembrane over the sample, while a radiation sensor is operated to detect photoluminescent radiation emitted by the nanomembrane in response to the laser beam. A spectral shift in the detected photoluminescent radiation emitted by the nanomembrane is determined, and thermal diffusivity/conductivity is calculated from the determined spectral shift of the photoluminescence. | 2019-01-03 |
20190003995 | DIFFERENTIAL SCANNING MICROCALORIMETER DEVICE FOR DETECTING DISEASE AND MONITORING THERAPEUTIC EFFICACY - The present disclosure provides devices and methods for diagnosing, monitoring the disease progression of, and/or evaluating the risk for developing a disease by detecting thermostable variants of proteins and/or metabolites in biological samples using differential scanning calorimetry. Also disclosed herein are methods for monitoring the efficacy of a particular therapeutic regimen in patients in need thereof. | 2019-01-03 |
20190003996 | COMBINED WATER CUT AND SALINITY METER - Disclosed is a flow meter and method for measuring water cut and salinity of a multiphase mixture. The water-cut meter includes a conduit configured to receive the multiphase mixture, and a probe array configured to measure a cross-sectional area of the conduit. The probe array includes a plurality of coaxial probes connected in parallel. Optionally, the probe array is configured to operate at a single high frequency, for example, 1 to 3 GHz, to minimize conductivity loss relative to capacitance. The flow meter further includes a processor configured to transmit a signal to the probe array and to receive a reflected signal from the probe array using a single channel. The processor is further configured to calculate the water cut and the salinity of the multiphase mixture based on a single complex permittivity of the multiphase mixture calculated from the received reflected signal. | 2019-01-03 |
20190003997 | SENSOR ELEMENT - An electrode for a sensor element 1 that detects a specific substance in a gas to be measured, wherein the electrode is embedded in an insulating substrate having a detection face to which the specific substance adheres, the electrode being embedded in such a manner that a part of the electrode is exposed at the detection face, the electrode comprises an alloy of Pt and at least one metal selected from the group consisting of Rh, Ru, Ir, Os, and Pd, and granular voids dispersed among the alloy, and the content of the metal in the alloy is 40 mass % or less, and the number of the granular voids per unit volume of the electrode for a sensor element is 3/100 μm | 2019-01-03 |
20190003998 | GRAPHITIC CARBON NITRIDE SENSORS - A sensor includes a substrate, a first electrode, a second electrode spaced from the first electrode, and a sensing medium on the substrate between the first electrode and the second electrode. The sensor medium includes a functionalized graphitic material and an uncondensed graphitic carbon nitride disposed upon the functionalized graphitic material. The sensor further includes a system for applying electromagnetic energy to the sensing medium to increase the conductance of the sensing medium, and circuitry including at least one measurement system in operative connection with the sensor to measure a variable relatable to the conductance of the sensing medium which is dependent upon the presence of an analyte to be detected. | 2019-01-03 |
20190003999 | Grid Coatings for Capture of Proteins and Other Compounds - Grids comprising a coating modified with one or more capture agents and a deactivating agent are disclosed. Methods of using such grids in connection with suitable microscopy techniques, such as for determining the structure of target compounds including proteins, are also disclosed. | 2019-01-03 |
20190004000 | SENSOR FOR ANALYTES - An electrochemical sensor is described that includes a counter electrode that prevents against electrical interference when measuring analytes in a fluid sample. The counter electrode can completely surround a working electrode and a reference electrode and can be held at a common potential voltage during operation. The counter electrode can have a U-shape for surrounding on three sides the working electrode and the reference electrode. | 2019-01-03 |
20190004001 | ELECTRO-CHEMICAL SENSOR AND COATING METHOD, PRODUCTION METHOD AND CORRESPONDING USES - The invention relates to an electro-chemical sensor and coating method, production method and corresponding uses. The coating method of an electro-chemical sensor comprises the following steps: coating a carbon-rich substrate, with a carbon content greater than or equal to 0 wt. % in relation to the total weight of the substrate, and with an organic polymer; and applying a cold plasma treatment to said coating. This method permits the production of electro-chemical sensors with a carbon-rich substrate, with a carbon content greater or equal to 50 wt. % in relation to the total weight of the substrate, and a modified organic polymer coating. These new sensors are suitable for the detection of, inter alia, dopamine, glucose, uric acid and ascorbic acid. | 2019-01-03 |
20190004002 | BIOSENSOR DEVICE AND METHOD FOR MANUFACTURING THEREOF AND METHOD FOR DETECTING BIOLOGICAL MOLECULES - A biosensor device includes a substrate plate, a metal conductive layer, a plurality of working electrodes and an insulating layer. The metal conductive layer is disposed over the substrate plate and has an upper surface. The working electrodes are disposed over the upper surface of the metal conductive layer, wherein each of the working electrodes has a top surface and each of the top surfaces is higher than the upper surface of the metal conductive layer. The insulating layer covers the metal conductive layer and surrounds the working electrodes, wherein an upper surface of the insulating layer is located between the top surfaces and the upper surface of the metal conductive layer such that the working electrodes protrude beyond the upper surface of the insulating layer. A method for manufacturing the biosensor device and a method for detecting biological molecules by using the biosensor device are also provided herein. | 2019-01-03 |
20190004003 | BINDING PROBE CIRCUITS FOR MOLECULAR SENSORS - In various embodiments a molecular circuit is disclosed. The circuit comprises a negative electrode, a positive electrode spaced apart from the negative electrode, and a binding probe molecule conductively attached to both the positive and negative electrodes to form a circuit having a conduction pathway through the binding probe. In various examples, the binding probe is an antibody, the Fab domain of an antibody, a protein, a nucleic acid oligomer hybridization probe, or an aptamer. The circuit may further comprise molecular arms used to wire the binding probe to the electrodes. In various embodiments, the circuit functions as a sensor wherein electrical signals, such as changes to voltage, current, impedance, conductance, or resistance in the circuit, are measured as targets interact with the binding probe. In various embodiments, the circuit provides a means to measure the presence, absence, or concentration of an analyte in a solution. | 2019-01-03 |
20190004004 | SOLID STATE ELECTRODES AND SENSORS HAVING REDOX ACTIVE SURFACE AREAS - Solid-state electrodes comprising Redox Active Surface Areas for use in analyte sensing devices and various product platform devices. | 2019-01-03 |
20190004005 | METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR - A method for sensing an analyte utilizing a sensor having a working electrode, the method includes providing the working electrode with an analyte-specific enzyme and a redox mediator, providing the working electrode to the analyte, accumulating charge derived from the analyte reacting with the analyte-specific enzyme and the redox mediator for a set period of time, connecting the working electrode to circuit after the set period of time, and measuring the signal from the accumulated charge. | 2019-01-03 |
20190004006 | POTENTIOSTAT CIRCUIT - A potentiostat circuit is described for the detection and analysis of analytes within an uncompartmented or galvanically connected pool of liquid and which permits sequential and simultaneous measurements to be performed in multiple electrochemical cells within the uncompartmented or galvanically connected pool of liquid by one or more potentiostats. Accordingly, the potentiostat circuit includes a grounded counter electrode that is configured to prevent against electrical interference when measuring analytes in a fluid sample. The grounded counter electrode can completely surround a working electrode and a reference electrode and can be held at a common potential voltage during operation. The grounded counter electrode can have a U-shape for surrounding on three sides the working electrode and the reference electrode. | 2019-01-03 |
20190004007 | MANUFACTURING METHOD OF GAS SENSOR - Disclosed is a manufacturing method of a gas sensor. The gas sensor has a plate-shaped sensor element with at least one pair of electrode pads, a separator disposed around the sensor element, and at least one pair of opposed metal terminals held in an insertion hole of the separator and electrically connected at contact regions thereof to the respective electrode pads. The manufacturing method includes mounting the metal terminals in the insertion hole of the separator with the use of a mounting jig. The mounting jig has a flat portion interposed between the contact regions of the metal terminals during the mounting of the metal terminals in the separator so as to prevent contact and entanglement of the opposed metal terminals. | 2019-01-03 |
20190004008 | GAS SENSOR ELEMENT AND GAS SENSOR - A gas sensor element including a solid electrolyte body, a sensor electrode, and a reference electrode is provided. The solid electrolyte body has oxygen ion conductivity and includes a measurement gas surface to be exposed to a measurement gas introduced from the exterior and a reference gas surface to be exposed to a reference gas introduced from the exterior. The sensor electrode is provided on the measurement gas surface of the solid electrolyte body. The reference electrode is provided on the reference gas surface of the solid electrolyte body. The sensor electrode includes a porous body containing a solid electrolyte having oxygen ion conductivity and a precious metal, the peak pore size of the sensor electrode being 0.03 μm to 0.3 μm. | 2019-01-03 |
20190004009 | BIO-SENSOR PIXEL CIRCUIT WITH AMPLIFICATION - A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes. | 2019-01-03 |
20190004010 | ONE-STEP CAPILLARY ISOELECTRIC FOCUSING AND MOBILIZATION OF ANALYTES - The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH | 2019-01-03 |
20190004011 | METHOD AND APPARATUS FOR ION MOBILITY SEPARATIONS UTILIZING ALTERNATING CURRENT WAVEFORMS - Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation. | 2019-01-03 |
20190004012 | PIPE INSPECTION TOOL - An inspection tool apparatus includes a core having an axial length. The axial length is determined based on a desired depth of inspection radially from the core. A plurality of arms are coupled to and extend radially from the core. The core and the plurality of arms comprise a high permeability magnetic material. The core or at least one of the plurality of arms is wound by a respective coil that is positioned to receive magnetic flux that is passing through the core or at least one of the plurality of arms. | 2019-01-03 |
20190004013 | CRACK MEASUREMENT DEVICE AND METHOD - According to an exemplary embodiment in the present disclosure, a crack measurement device and a crack measurement method are provided. The crack measurement device according to an exemplary embodiment in the present disclosure includes: an ultrasonic sensor irradiating a first ultrasonic wave in a direction perpendicular to a bottom surface of an object to be inspected, so as to be focused on the bottom surface of the object to be inspected and receiving a reflected wave, reflected from the bottom surface of the object to be inspected; and a monitoring unit providing information on a crack on the basis of intensity of the reflected wave. | 2019-01-03 |
20190004014 | APPARATUS, SYSTEMS, AND METHODS FOR DETERMINING NONLINEAR PROPERTIES OF A MATERIAL TO DETECT EARLY FATIGUE OR DAMAGE - An inspection apparatus detects one or more characteristics of a material sample and includes a transmitter to transmit an initial signal to the material sample, and a receiver to receive a detected signal from the material sample associated with the initial signal. The detected signal has at least a first harmonic signal component and a second harmonic signal component. Data processing circuitry determines a resonant frequency of the first harmonic signal component and an amplitude of the first harmonic signal component at the resonant frequency, and filters the detected signal using a first filter signal having a frequency corresponding to the first harmonic signal component and a second filter signal having a frequency corresponding to the second harmonic signal component. A frequency analysis is performed in the frequency domain on the filtered first and second signals to determine corresponding first and second amplitudes. The first and second amplitudes may be compensated for nonlinearity. One or more nonlinear parameters are determined based on the first and second amplitudes. A user interface communicates one or more characteristics of the material sample based on the first and second compensated amplitudes. | 2019-01-03 |
20190004015 | METHOD FOR OBTAINING DATA RELATING TO THE ELASTICITY OF MATERIALS, USING TORSIONAL WAVES - The invention relates to a method or operating mode which, using a device for emitting and receiving sonic and/or ultrasonic torsional waves, can be used to obtain data relating to the consistency or elasticity of quasi-incompressible solid media, preferably quasi-fluids or biological tissues, based on the separation of non-linear parameters. | 2019-01-03 |
20190004016 | CHROMATOGRAPH DEVICE - A chromatograph device which makes it possible to suppress a carry-over phenomenon. A sample injection unit for collecting a liquid sample and injecting a predetermined amount of liquid sample into a mobile phase; a sample introduction tube a distal end section of which has a needle formed therein and a terminal end section of which is connected to the sample injection unit; a separation column which is coupled via a column coupling tube to the sample injection unit, and through which the mobile phase where the liquid sample has been injected passes; and a detection unit that is connected to the separation column and detects a component in the liquid sample. The column coupling tube is provided with an ultrasonic vibrator for vibrating the tube. | 2019-01-03 |