| Entries |
| Document | Title | Date |
|---|
| 20100261658 | PEPTIDE FOR ACTIVATING AQUAPORIN SYNTHESIS - The present invention concerns a peptide of the general formula (I):
| 10-14-2010 |
| 20100267642 | USE OF COMPLEX FORMS OF CALMODULIN-LIKE SKIN PROTEIN CLSP - The present invention relates to the use of a complex form of calmodulin-like skin protein (CLSP), of polypeptides derived from this protein or of analogues thereof, as a marker for evaluating a state of an epithelium. | 10-21-2010 |
| 20100273718 | Milk Protein Hydrolyzates with Reduced Immunogenic Potential - Hydrolyzate compositions comprising at least one milk protein or whey hydrolyzed with at least one proteolytic enzyme are provided. The hydrolyzates reduce the immunogenicity of the milk or whey protein in a subject predisposed to having an immune reaction to the protein. Methods for making the compositions are also provided, as food products and nonfood products comprising the compositions. | 10-28-2010 |
| 20100279946 | USE OF AN ACTIVE PRINCIPLE FROM FLAX FOR USE IN A COMPOSITION FOR ACTIVATING CYTOCHROME C - The present invention concerns the use, in a cosmetic composition, of an effective quantity of active principle originating from flax (genus | 11-04-2010 |
| 20100286056 | COMPOSITIONS FOR REDUCING OXIDATIVE STRESS AND USES THEREOF - The present invention relates to the use of one or more tripeptides selected from the group consisting of | 11-11-2010 |
| 20100298231 | PMMA BINDING PEPTIDES - Peptides are provided that have binding affinity for polymethyl methacrylate (PMMA). The polymethyl methacrylate-binding peptides may be used to prepare peptide-based reagents suitable for use in a variety of applications. The peptide-based reagents may be used to couple benefit agents to a PMMA polymer surface or may be used to couple a benefit agent comprising a PMMA polymer surface to a target surface, such as a body surface. | 11-25-2010 |
| 20100311667 | NOVEL COMPOUNDS, USE THEREOF IN COSMETIC AND COSMECEUTIC APPLICATIONS, AND COMPOSITIONS COMPRISING SAME - A compound of the formula I: R-A-Gly-His-B (I) wherein: A and B are independently of each other a L-lysine residue, a D-lysine residue, or a L- or D-lysine residue in which the NH | 12-09-2010 |
| 20100311668 | PERSONAL CARE AND COSMETIC COMPOSITION CONTAINING TETRAPEPTIDES WITH THE MOTIFS GX1X2G, PX1X2P, OR PX1X2K - The present invention relates to topical personal care and skin care compositions comprising: a) a safe and effective amount of a tetrapeptide selected from the group of tetrapeptides with the motif GX | 12-09-2010 |
| 20100331260 | Stabilized bitamin c derivatives having a peptide molecule, preparation method thereof, and composition containing the same - The present invention relates to a stabilized vitamin C derivative with a peptide molecule linked to vitamin C or a pharmaceutically acceptable salt thereof, a method of preparing the same, and a composition containing the same. | 12-30-2010 |
| 20110021438 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING THEM AND USES THEREOF - The invention concerns novel compounds of the N-acylamino-amide family, compositions, in particular cosmetic or pharmaceutical, containing them, and their use for treating body or face skin ageing, whether chronobiologic or light-induced, and in particular skin ageing caused by decrease of skin elasticity and/or by collagen degradation in the structure of tissues. | 01-27-2011 |
| 20110021439 | USE OF TRANSESTERIFIED OLIVE OIL IN THE COSMETIC FIELD - The use of transesterified olive oil for increasing the penetration rate of cosmetically-active and/or dermatologically-active ingredients or as cosmetic moisturiser is disclosed. | 01-27-2011 |
| 20110034393 | USE OF A NOVEL NATURAL AGENT IN COSMETIC COMPOSITIONS - The invention relates to cosmetic or dermatological compositions containing mannoproteins as an active ingredient and/or adjuvant, to the use of said cosmetic or dermatological compositions and to cosmetic treatment methods. | 02-10-2011 |
| 20110034394 | COMPOSITION COMPRISING PROTEIN AND DISPERSE FAT - The present invention relates to a method for the manufacture of a composition comprising proteins and fats, said method providing a simple and non-expensive way of obtaining fat-containing proteinaceous products of high nutritional value that are easy to handle and at the same time possess high stability towards coalescence and oxidation. More particularly, a method is provided for the manufacture of a composition comprising protein and fat in disperse form, the method comprising the following steps: (i) providing a suspension having a pH value higher than 7.0, said suspension comprising water, proteinaceous material, fat, and optionally alkali; (ii) incubating the suspension from (i) at a temperature in the interval 50-150° C.; (iii) homogenizing the suspension from (ii) to form a dispersion; and (iv), if desired, subjecting the dispersion from (iii) to a subsequent treatment; wherein the proteinaceous material in step (i) comprises vegetable-based proteinaceous material, and/or yeast-based proteinaceous material; wherein the suspension in step (i) comprises at least 5% fat by weight of dry matter. The current invention also relates to the compositions obtained by the method and to compositions obtainable by the method of the invention and, further, to the use of these compositions. | 02-10-2011 |
| 20110092439 | METHOD OF PROMOTING WOUND HEALING - The present disclosure relates to methods of administering relaxin to promote wound healing and reduce scar formation. The disclosure further contemplates the use of relaxin in reconstructive and plastic surgery. | 04-21-2011 |
| 20110098230 | COSMETIC USE OF ANNEXIN II-TYPE PROTEINS FOR TREATING DRYNESS OF THE SKIN - The present invention relates to the use, in particular cosmetic and/or therapeutic use, of annexin II, of polypeptides derived from this protein or of analogues thereof, of a nucleic sequence encoding such a polypeptide or of a modulator of the activity, the stability or the expression of such a polypeptide, in particular for preventing and/or treating the signs of skin dryness. | 04-28-2011 |
| 20110098231 | Skin Cosmetic - A skin cosmetic comprising the following ingredients (A), (B), and (C), and also satisfying the condition (D):
| 04-28-2011 |
| 20110105406 | Transparent Cosmetic Compositions - The present invention relates to a cosmetic composition comprising: a) from about 0.05% to about 10% of a salt form active; b) from about 0.001% to about 2% of a thickening agent; and c) water, wherein the composition has a turbidity no higher than about 10 NTU, and has a pH in the range of about 5.0 to about 6.8. | 05-05-2011 |
| 20110130338 | USE OF SERINE PROTEASE INHIBITORS IN THE TREATMENT OF SKIN DISEASES - This invention relates to therapeutic compounds which are inhibitors of serine proteases, to pharmaceutical compositions thereof and to their use in the treatment of the human or animal body. More specifically, the present invention relates to a method for the treatment, diagnosis or prognosis of skin diseases comprising the administration to a subject in need thereof of a therapeutically effective amount of a Serine protease inhibitor. | 06-02-2011 |
| 20110130339 | COSMETIC COMPOSITION FOR SKIN CELL REGENERATION MIMICKING EXTRACELLULAR MATRIX - The present invention relates to a cosmetic composition which mimics the extracellular matrix to stimulate the regeneration of skin cells, and more particularly to a cosmetic composition which contains active ingredients consisting of low-molecular-weight materials, which easily permeate through the skin, at a composition ratio similar to that in the extracellular matrix. The cosmetic composition stimulates the repair of the skin to maintain homeostasis and is effective for the regeneration of skin cells. | 06-02-2011 |
| 20110144030 | CONJUGATE OF HYALURONIC ACID FOR COSMETIC TREATMENT AND PREPARATION METHOD - This invention discloses a new conjugate compound that comprises at least one HA oligomer derivatised through one thiolated linker, whereby it binds to at least one metal nanoparticle, such as, for example, a gold nanoparticle. Moreover, it discloses methods of obtaining it, as well as the use thereof in a cosmetic treatment, and cosmetic compositions that contain them. | 06-16-2011 |
| 20110152198 | PHARMACEUTICAL COMPOSITIONS CONTAINING BOTULINUM TOXIN - This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides. In some embodiments, the average molecular weight of a disaccharide unit of the polysaccharide is between about 345 D and about 1,000 D. | 06-23-2011 |
| 20110160145 | TREATMENT OF FINE WRINKLES WITH CLOSTRIDIA NEUROTOXINS - Methods of using clostridial toxins and other biological agents to thin skin and control fine wrinkles in humans are provided. In preferred embodiments the methods provide beneficial effects in humans. | 06-30-2011 |
| 20110172161 | Composition for therapeutic and cosmetic botulinum toxin - This invention relates to a composition of botulinum based pharmaceuticals used for therapeutic and cosmetic treatment. This invention offers an improvement on the prior art by eliminating the potential of blood-borne contamination with botulinum based pharmaceuticals. Recombinant serum albumin is taught for use in the place of human serum albumin as a stabilizing or enhancing agent. | 07-14-2011 |
| 20110183913 | NOVEL LIPID DIPEPTIDE AND GEL - There is provided a gelator that is capable of forming a gel by an extremely small amount of addition in a wide pH range from acidic to alkaline regions, and a gel having high environmental compatibility, biocompatibility, and biodegradability. A gelator comprising: a lipid peptide of Formula (1) wherein R | 07-28-2011 |
| 20110183914 | Personal Care Compositions - Personal care compositions comprising a dipeptide and methods of using such compositions to treat the condition of keratinous tissue. The C terminal amino acid of said dipeptide is threonine. The personal care composition can be applied topically, ingested orally, injected, or used as part of a combined treatment regimen. | 07-28-2011 |
| 20110212897 | WNT3A FOR INHIBITION OF SCARRING - Provided is WNT3A, or a therapeutically effective fragment or derivative thereof, for use as a medicament for the prevention, reduction or inhibition of scarring. Also provided is a method of preventing, reducing or inhibiting scarring, the method comprising administering a therapeutically effective amount of WNT3A, or a therapeutically effective fragment or derivative thereof, to a patient in need of such prevention, reduction or inhibition. The methods and medicaments of the invention are suitable for use in the prevention, reduction or inhibition of scarring arising as a result of healing of a wound, or scarring associated with a fibrotic disorder. The methods and medicaments disclosed are of particular use in preventing, reducing or inhibiting scarring of the skin. | 09-01-2011 |
| 20110218153 | Topical Glutathione Formulations For Menopausal Skin - Topical compositions to address menopausal skin conditions comprise an effective amount of S-acyl glutathione derivative and a carrier. Methods for addressing menopausal skin conditions comprise applying a composition containing S-acyl glutathione derivative in a dermatologically acceptable carrier to skin tissue. The acyl group is a saturated or unsaturated aliphatic C | 09-08-2011 |
| 20110245182 | Topical Uses of Szeto-Schiller Peptides - Provided are methods for improving the appearance aging or of peri-menopausal, menopausal, or post-menopausal skin comprising: applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition comprising at least one Szeto-Schiller peptide and a dermatologically acceptable carrier. Compositions for use in the methods are also provided. | 10-06-2011 |
| 20110245183 | Topical Uses of Szeto-Schiller Peptides - Provided are methods for improving the appearance aging or of peri-menopausal, menopausal, or post-menopausal skin comprising: applying to the skin tissue of a mammal in need of such regulation, a safe and effective amount of a composition comprising at least one Szeto-Schiller peptide and a dermatologically acceptable carrier. Compositions for use in the methods are also provided. | 10-06-2011 |
| 20110269693 | Apparatus for treatment of dermatological conditions - This invention relates to ultrasound delivery apparatus comprising flexible arrays of transducers and to methods and topical compositions for the treatment of skin, in particular for the treatment of cosmetic skin conditions and to improve the appearance of sun damaged and/or aged skin; the invention further relates to the use of such apparatus and compositions in methods of treating skin, which methods may incorporate the application of ultrasound. The composition may comprise one or more anti-gfycation agent, one or more anti-oxidant, a dermatologically acceptable excipient and optionally one or more substance capable of inducing expression of a molecular chaperone. | 11-03-2011 |
| 20110269694 | NOVEL ANTI-AGING PEPTIDES AND COSMETIC AND/OR PHARMACEUTICAL COMPOSITION CONTAINING SAME - The present invention relates to peptide compounds of general formula (I) | 11-03-2011 |
| 20110269695 | NOVEL ANTI-AGING PEPTIDES AND COSMETIC AND/OR PHARMACEUTICAL COMPOSITION CONTAINING SAME - Peptide compounds of general formula (I) R | 11-03-2011 |
| 20110301091 | COMPOSITIONS AND METHODS FOR REDUCING THE SIGNS OF AGING OF THE SKIN - Compositions and methods used to reduce the visible signs of aging of the skin by recalibrating the expression of genes, genetic networks, and cellular pathways in the human skin, particularly using combinations of natural compounds that produce synergistic effects on the expression of genes and genetic networks. | 12-08-2011 |
| 20120040912 | PROTEASOME-ACTIVATING ANTI-AGING PEPTIDES AND COMPOSITIONS CONTAINING SAME - The present invention relates to peptidic compounds of general formula (I): | 02-16-2012 |
| 20120094919 | USE OF TRIPEPTIDES - The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican. | 04-19-2012 |
| 20120094920 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING A PEPTIDIC HYDROLYZATE THAT CAN REINFORCE THE BARRIER FUNCTION - The invention relates to a peptidic hydrolyzate enriched in bioactive peptide, capable of reinforcing the skin barrier function and stimulating epidermal differentiation. The invention is also relative to a cosmetic and/or pharmaceutical composition comprising, in a physiologically acceptable medium, said hydrolyzate as active principle. The invention further relates to the use, in a cosmetic composition, of the active principle according to the invention to activate the HMG-CoA reductase in the cutaneous cells, and to prevent and combat the cutaneous signs of aging and photo-aging. | 04-19-2012 |
| 20120094921 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING A RELIEVING PEPTIDIC HYDROLYZATE - The invention concerns a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, a peptide hydrolyzate which is enriched in soothing bioactive peptide. The invention also concerns the use, in a cosmetic composition, of the active principle in accordance with the invention to activate HMG-CoA reductase in skin cells and to prevent or combat skin irritations. | 04-19-2012 |
| 20120129786 | NOVEL COMPOSITION - The present invention relates to compositions comprising a peptide with 2-12 amino acids substituted with a lipophilic moiety and a water soluble salt of an alkali, earth alkaline metal or transition metal. Furthermore, the invention relates to a container comprising such compositions. Additionally, the invention relates to the use of a water soluble salt of an alkali, earth alkaline metal or transition metal for reducing the adhesion of a peptide with 2-12 amino acids substituted with a lipophilic moiety to a surface. | 05-24-2012 |
| 20120135937 | INJECTABLE COMBINATION OF ADRENERGIC RECEPTOR AGONISTS WITH FILLERS, FOR DECREASING SKIN REACTIONS DUE TO INJECTION - The present invention concerns an injectable composition comprising a filler or a botulinum toxin and an adrenergic receptor agonist, and its use for diminishing, decreasing or avoiding skin reactions due to injection, specially redness, ecchymosis, bruising, bleeding, erythema, oedema, necrosis, ulceration, swelling and/or inflammation. | 05-31-2012 |
| 20120157388 | EXTERNAL COMPOSITION FOR SKIN - A moisturizing agent comprising one or more than one compound selected from the group consisting of lysyl-β-alanine represented by the following general formula (1) and a salt thereof: | 06-21-2012 |
| 20120172308 | Oligopeptides And Their Use In Cosmetics - The present invention relates to the cosmetic use of oligopeptides, cosmetic preparations which comprise such oligopeptides as well as certain oligopeptide derivatives themselves. | 07-05-2012 |
| 20120172309 | TRANSGLUTAMINASE-ACTIVATING PEPTIDE AND COSMETIC OR PHARMACEUTIAL COMPOSITION CONTAINING SAME - The present invention relates to a peptide of general formula (I): | 07-05-2012 |
| 20120190627 | COSMETIC USE OF LACRITIN-TYPE POLYPEPTIDES - The present invention is directed to the use, in particular cosmetic use, of an effective amount of at least one lacritin-type polypeptide, of an analogue thereof or of a fragment thereof, of at least one nucleic acid sequence encoding this polypeptide, or of at least one agent that modulates the activity, the stability or the expression of this polypeptide, or its interaction with syndecan-1, as an agent useful for the care of the skin and of appendages thereof. | 07-26-2012 |
| 20120238506 | ACACIA MACROSTACHYA SEED EXTRACT AND COMPOSITIONS CONTAINING SAME - The invention relates to a composition containing an extract of seeds of | 09-20-2012 |
| 20120245098 | Topical Palmitoyl Glutathione Formulations - A topical composition for application to aging skin, comprising an effective amount of S-acyl glutathione derivative of formula (I) | 09-27-2012 |
| 20120309689 | HATCHING FLUID ENZYMES AND USES THEREOF - The present invention relates to various polypeptides from fish hatching fluid, their encoding nucleic acid sequences, pharmaceutical compositions comprising said polypeptides and nucleic acid molecules and their use in various medical and cosmetic applications to the skin, particularly for moisturizing skin and/or for exfoliation of the horny layer of the skin for treating or preventing skin disorders or conditions in an animal. | 12-06-2012 |
| 20130018000 | RECOMBINANT FILAGGRIN POLYPEPTIDES FOR CELL IMPORTATION - Disclosed are recombinant polypeptides that include (a) a filaggrin amino acid sequence and (b) a cell importation signal sequence that includes a motif of two to fifteen amino acids, wherein the motif includes at least one arginine residue and at least one methionine residue. Also disclosed are nucleic acids encoding the recombinant polypeptides of the present invention, and compositions that include the recombinant polypeptides and nucleic acids of the present invention. Methods of treating or preventing a skin disease or skin disorder using the compositions of the present invention are also included, as well as kits that include a sealed containing that includes a recombinant polypeptide of the present invention. | 01-17-2013 |
| 20130029917 | USE OF A PEPTIDE HYDROLYSATE OF PEA AS MOISTURIZING ACTIVE AGENT - The invention relates to the cosmetic use of a peptide hydrolysate of pea ( | 01-31-2013 |
| 20130053327 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF - A novel polypeptide isolated from the cornified envelope, polypeptides similar to the latter or fragments of the polypeptide as well as a cosmetic and/or pharmaceutical composition containing same are described. The mainly cosmetic and/or therapeutic use of the polypeptide, or similar polypeptides or fragments of the amino acid sequence of the polypeptide, or an encoding nucleotide sequence for the polypeptide, to reinforce the barrier function of the epidermis and prevent and/or treat the signs of skin dryness or prevent and/or treat disorders of the barrier function or the fragilisation of the epidermis. Finally, the isolated encoding polynucleotide for the polypeptide are also disclosed. | 02-28-2013 |
| 20130102540 | Compositions and Methods for Skin Treatment - Compositions for the treatment of the skin. The compositions reduce and/or reverse the visible appearance of skin damage. In the preferred embodiment, the composition includes Retinyl Palmitate Polypeptide; Ascorbylmethylsilanol Pectinate; Tocopheryl Polypeptide; Cholecalciferol Polypeptide; and Niacinamide Polypeptide. | 04-25-2013 |
| 20130116194 | COSMETIC COMPOSITION FOR RESTORING LIPIDIC LAYER OF THE STRATUM CORNEUM IN ORTHORHOMBIC - The present invention refers to a cosmetic composition of the oil-in-glycol type comprising (a) at least one sucrose non-ionic surfactant or derivatives thereof, (b) at least one fatty alcohol, (c) at least one glycol and (d) at least one ingredient selected from aminoacid and/or peptide, as well as associated uses, products and methods. The composition of the invention is capable of restoring the cutaneous barrier, reorganizing the lipidic layer of the stratum corneum in orthorhombic, conceding hydration, renewal and cellular energization in the long run. In a particular embodiment, said composition can be used simultaneously as an emulsifying system for preparing cosmetic products, for example, in the preparation of creams, lotions, etc. | 05-09-2013 |
| 20130157957 | Moisturizing Composition Comprising an Aminopeptide Mixture - The invention is directed to skin moisturizing compositions comprising an aminopeptide mixture. The composition replenishes the skins natural moisturization factor and delivers excellent sensory benefits. The composition is not unpleasantly viscous during and after application. | 06-20-2013 |
| 20130165388 | Method of Producing a Paralytic Peptide - The invention relates to a low molecular weight peptide (or suite of related peptides) isolated from the submaxiliary saliva glands of shrews of the species | 06-27-2013 |
| 20130231291 | FERMENTED SOYA BASED MIXTURE COMPRISING ISOFLAVONES- AGLICONES, EQUOL AND LUNASIL, PROCESS FOR THE PREPARATION AND USES THEREOF IN FOOD, MEDICAL AND COSMETIC FIELDS - The present invention concerns a mixture comprising isoflavones-aglicones, such as daidzein, genistein and glycitein, in addition to equol and lunasin, said mixture being based on soya fermented using lactic acid bacteria isolated from food matrices and use of said mixture for protection of skin and similar and of human intestinal cells with particular reference to prevention of inflammatory state and protection of barrier functions and hair loss treatment. | 09-05-2013 |
| 20130244948 | COMPOSITIONS OF CELLS, MEDIA, AND METHODS THEREOF - The disclosure provides a composition that comprises co-culture of small embryonic-like stem cells and mesenchymal stem cells, where cell media is reduced or lacking in exogenously supplied growth factors, as well as compositions of growth media that result from, or are manufactured by, co-culture of at least two types of different cells. Also provided are methods for selecting cell media that meet criteria pertaining to cell migration (gap assays) and to confluence. | 09-19-2013 |
| 20130252903 | COMPOSITIONS FOR REDUCING OXIDATIVE STRESS AND USES THEREOF - The present invention relates to the use of one or more tripeptides selected from the group consisting of | 09-26-2013 |
| 20130261063 | ADMINISTRATION OF CELLS AND CELLULAR EXTRACTS FOR REJUVENATION - The invention describes methods and agents for improving cosmetic appearance, for promoting, improving or restoring health of cells and tissues, preferably skin, and more preferably, for restoring aged or damaged skin to a healthy appearance. In some embodiments, the invention relates to compositions of cells, eggs, cell extracts, egg extracts, and extract components such as purified nucleic acids, polypeptides, lipids, carbohydrates or other natural products. | 10-03-2013 |
| 20130288978 | DERMATOPONTIN-ACTIVATING PEPTIDES AND COSMETIC COMPOSITIONS INCLUDING SAME - This invention relates to peptides activating dermatopontin in the skin. | 10-31-2013 |
| 20130296251 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING A YEAST PEPTIDE HYDROLYSATE AND USE OF THE YEAST PEPTIDE HYDROLYSATE AS AN ACTIVE AGENT FOR STRENGTHENING HAIR - A method of attenuating or preventing hair loss in a human in need thereof comprising applying to the human in need thereof a composition comprising an effective amount of a hair-loss attenuating peptide hydrolysate and a cosmetically acceptable carrier. | 11-07-2013 |
| 20130324476 | COSMETIC USE OF DERMICIDIN, AND ANALOGUES OR FRAGMENTS THEREOF - The present invention relates, in particular, to the use of a sequence of amino acids of dermicidin or an analogue or fragment thereof, and at least one sequence of nucleic acids coding said sequence as a biomarker for ageing skin and/or the signs of skin ageing which are possibly associated with skin dryness. | 12-05-2013 |
| 20130324477 | PEPTIDES THAT MODULATE COMPLEX SASPASE-FLG2 - The invention relates to a peptide isolated from SASpase or FLG2, a fragment or homologue thereof, which can modify the three-dimensional shape of a complex formed by interaction between a first amino acide sequence from Filaggrin-2 and a second amino acid sequence from SASPase. | 12-05-2013 |
| 20130331332 | COMPOSITION COMPRISING PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA - An injectable composition comprising peroxisome proliferator-activated receptor-gamma for subcutaneous administration and a method for improving imperfections of the skin, wherein the injectable composition is subcutaneously administered at the area of skin imperfections comprising the steps: a) identifying an area of skin imperfections, b) administering a safe and cosmetically effective amount of the composition subcutaneously to the area of skin imperfections. | 12-12-2013 |
| 20130338078 | SKIN CARE FORMULATIONS INCLUDING OCTAPEPTIDE COMPLEXES AND METHODS FOR THEIR MANUFACTURE - The present invention relates to skin care formulations including octapeptide complexes. A preferred embodiment of the skin care formulation is a multi-active serum, which treats numerous skin problems associated with environmental exposure and aging. In one aspect, the multi-serum may be formulated for treatment of facial skin, and may optionally be applied as a mask. In another aspect, the multi-active serum may be formulated specifically for the treatment of delicate skin in the under-eye area of the fact. This embodiment of the invention may be applied as an under eye mask. In yet another aspect, the invention provides a method of manufacturing skin care formulations including octapeptide complexes. | 12-19-2013 |
| 20140045766 | NOVEL ANTI-AGING PEPTIDES AND COSMETIC AND/OR PHARMACEUTICAL COMPOSITION CONTAINING SAME - Methods of restoring the circadian rhythm and resynchronizing the biological clock of cells are described. The methods include topically applying a topical composition comprising a cosmetically acceptable medium and an effective quantity of a peptide compound of general formula (I), R | 02-13-2014 |
| 20140045767 | Topical Palmitoyl Glutathione Formulations - A topical composition for application to aging skin, including an effective amount of S-acyl glutathione derivative of formula (I) | 02-13-2014 |
| 20140051640 | PLANT PROTEIN AND MINERAL POWDER-BASED COLLAGEN MASK - The present patent application relates to a plant protein and mineral powder-based collagen mask, comprising the following constituents by weight percentage: Soya Protein: 1.2-1.5; Ethylene Glycol Phenyl Ether: 0.2-0.5; the rest is purified water. The plant protein and mineral powder-based collagen mask produced by the formula of the present patent application has a strong hydrating function. The moisture content of the plant protein and mineral powder-based collagen mask can be as high as 90%. When meet 37-38 degree body temperature, the plant protein and mineral powder-based collagen mask will release moisture slowly and fully releases after 4-5 hours, so that the skin always keep being moist. Meanwhile, the plant protein and mineral powder-based collagen mask of the present patent application will not suck back the moisture of the skin. | 02-20-2014 |
| 20140057850 | PEPTIDE FOR USE IN THE TREATMENT OF SKIN CONDITIONS - The present invention relates to a peptide of the following formula (I) X | 02-27-2014 |
| 20140066380 | PEPTIDE FRAGMENTS FOR INDUCING SYNTHESIS OF EXTRACELLULAR MATRIX PROTEINS - Short biologically active tetrapeptides are disclosed that are comprised of the sequences GxxG and PxxP where G (glycine) and P (proline) are maintained and x is a variable amino acid. The peptides can be used singly or in combination to stimulate production of extracellular matrix proteins in skin. A rapid, low-cost method of producing heterogenous formulations of tetrapeptides is disclosed. | 03-06-2014 |
| 20140066381 | NOVEL PEPTIDES THAT ARE MODULATORS OF THE PROTEIN TRF2 AND COMPOSITIONS CONTAINING SAME - Peptide compounds of the following general formula (I): | 03-06-2014 |
| 20140080761 | PROTEOGLYCAN-CONTAINING MATERIAL - The present invention was made in view of an object to produce a novel proteoglycan-containing material, and find a novel use and/or a superior effect of the proteoglycan-containing material. The present invention provides a proteoglycan-containing material obtained from fish cartilage, wherein the proteoglycan-containing material comprises an acidic saccharide component having a molecular weight of not less than 2000 kDa. The proteoglycan-containing material provides advantageous effects for skin-moisturizing and skin anti-aging, including a superior skin fibroblast proliferation effect, an effect of enhancing and improving the skin barrier function, an effect of enhancing and improving the skin's capability to produce collagen, a dermis-thickening inhibition effect, and the like. | 03-20-2014 |
| 20140100170 | PLANT-DERIVED ELASTIN BINDING PROTEIN LIGANDS AND METHODS OF USING THE SAME - The present invention describes novel plant derived elastin-like peptides and peptidomimetics that may serve as functional ligands for elastin receptors and stimulate elastogenesis. The novel plant derived peptides provide an alternative (non-animal derived) source of GXXPG (SEQ ID NO. 2) containing peptides. The present invention also describes therapeutic compositions containing novel plant derived peptides or peptidomimetics useful in stimulating elastogenensis and capillary dilatation. The therapeutic compositions of the present invention that comprise novel plant derived peptides or peptidomimetics may be combined with other therapeutic agents. | 04-10-2014 |
| 20140100171 | Methods of Improving the Appearance of Aging Skin - A method of improving the appearance of aging skin includes applying to skin tissue having dullness or lack of radiance, or eleven lines, marionette lines, or horizontal forehead lines, or sagging skin, a composition containing S-acyl glutathione derivative having unsaturated or saturated C | 04-10-2014 |
| 20140113868 | PEPTIDE ANALOGUES WITH AN EXCELLENT MOISTURIZING EFFECT AND USE THEREOF - The present invention relates to a peptide analogue or a pharmaceutically acceptable salt thereof with excellent moisturizing effect, and use thereof for moisturization. More specifically, the present invention relates to a novel peptide analogue or a pharmaceutically acceptable salt thereof, a method for preparation thereof, a moisturizing cosmetic composition comprising the same as an active ingredient, and a pharmaceutical composition for prevention and treatment of xeroderma. | 04-24-2014 |
| 20140135269 | Peptide And Protein-Based Formula For Improving The Appearance Of Skin - The present invention relates to methods and compositions for or treating human skin to reduce the visible appearance of fine lines and wrinkles as well as to enhance the skin's luminosity comprising applying an effective amount of a cosmetic composition of the invention to the skin for a period of time. | 05-15-2014 |
| 20140148394 | COMPOSITIONS AND METHODS FOR MODULATING GAMMA-C-CYTOKINE ACTIVITY - The various embodiments relate to peptide antagonists of γc-family cytokines, Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), Interleukin-15 (IL-15), and Interleukin-21 (IL-21). The γc-cytokines are associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (GvHD). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools. Traditional approaches to inhibiting γc-cytokine activity involve raising neutralizing antibodies against each individual γc-cytokine family member/receptor subunit. However, success has been limited and often multiple γc-cytokine family members co-operate to cause the disease state. Combinatorial use of neutralizing antibodies raised against each factor is impractical and poses an increased risk of adverse immune reactions. The present embodiments overcome these shortcomings by utilizing peptide antagonists based on the consensus γc-subunit binding site to inhibit γc-cytokine activity. Such approach allows for flexibility in antagonist design. In several embodiments, peptides exhibit Simul-Block activity, inhibiting the activity of multiple γc-cytokine family members. | 05-29-2014 |
| 20140179616 | PEPTIDES THAT STIMULATE SUBCUTANEOUS ADIPOGENESIS - Peptides of 5 to 14 amino acids in length that stimulate subcutaneous adipogenesis and uses thereof are provided. | 06-26-2014 |
| 20140235547 | In Vivo Synthesis of Elastic Fiber - Disclosed herein are methods of restoring elasticity in tissue using tropoelastin containing compositions. | 08-21-2014 |
| 20140296155 | ANTI-STRETCH MARK SKIN CREAM AND METHOD FOR MAKING AND USING THEREOF - A skin cream and method for making and applying the skin cream having, e.g., a copper component, an ascorbic acid component, a lipid component and a peptide component. The peptide component can include palmitoyl pentapeptide (KTTLS) or hydrolized serecin. The copper component can be a copper solubilizing formulation. The copper solubilizing formulation can include one of (I) copper and a copper-complexing peptide and/or (ii) a copper-complexing protein. The combination of copper and the ascorbic acid component can prevent or reduce a destabilization of the ascorbic acid component. | 10-02-2014 |
| 20140309173 | Peptides For Skin Rejuvenation And Methods Of Using The Same - The invention provides compositions for stimulating the formation of one or more extracellular matrix components that contain a lipoaminoacid derivative of the tripeptide carnosine such as N-Octanoyl Carnosine. Also provided are compositions containing N-Octanoyl Carnosine in combination with selected tripeptide and/or tetrapeptides as well as pharmaceutical and/or cosmetic compositions containing such compositions. The invention further provides methods of using the compositions and compositions of the invention to treat, alleviate, and/or ameliorate a symptom, condition, disorder, or disease of the skin or mucosa, wherein the symptom, condition, disorder, or disease is associated with changes in extracellular matrix components. | 10-16-2014 |
| 20150038428 | ORGANOGELS AND EMULSIONS FOR BIOLOGICAL AND NON-BIOLOGICAL APPLICATIONS - The present invention relates to organogels and emulsions based on ultrasmall self-assembling peptides. It further relates to methods for producing such organogels and emulsions as well as to the use of the organogels and emulsions in biological and non-biological applications. | 02-05-2015 |
| 20150087597 | POLYPEPTIDES AND METHODS OF USE - Described herein are fragments of fibronectin and vitronectin and variants thereof that have certain activities, including growth factor-binding activity. Also described are fragments of growth factors that bind to fibronectin and inhibit binding of full-length growth factors to fibronectin. Compositions containing such fragments are useful in cosmetic treatments (e.g., the treatment of wrinkles or UV photodamage of skin), and the treatment of wounds and cancer. | 03-26-2015 |
| 20150094269 | SILK PROTEIN FRAGMENT COMPOSITIONS AND ARTICLES MANUFACTURED THEREFROM - A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. | 04-02-2015 |
| 20150094270 | PEPTIDE FRAGMENTS FOR INDUCING SYNTHESIS OF EXTRACELLULAR MATRIX PROTEINS - Short biologically active tetrapeptides are disclosed that are comprised of the sequences GxxG and PxxP where G (glycine) and P (proline) are maintained and x is a variable amino acid. The peptides can be used singly or in combination to stimulate production of extracellular matrix proteins in skin. A rapid, low-cost method of producing heterogenous formulations of tetrapeptides is disclosed. | 04-02-2015 |
| 20150105325 | RECOMBINANT ALPHA-FETOPROTEIN AND COMPOSITIONS THEREOF - Disclosed are pharmaceutical and synergistic compositions comprising human recombination alpha-fetoprotein expressed in eukaryotic cells for preparation of therapeutic agents for use in oncology, immunotherapy, stem cell therapy and cosmetology and also for the diagnosis of cancer and embryonic pathologies. | 04-16-2015 |
| 20150148297 | OLEANOYL PEPTIDE COMPOSITION AND COLLAGEN ENHANCEMENT - Disclosed is the a method of skin repair and firming, said method comprising the step of bringing into contact a pentapeptide conjugate of oleanolic acid with skin cells so that the effect of increased cellular communication at the molecular level to bring about gene and protein expression in the cells of the skin that enable repair and firming is realized. The invention demonstrates the effect of the pentapeptide conjugate of oleanolic acid in increasing Transforming Growth Factor-β and Fibroblast Growth Factor gene expressions in the skin. | 05-28-2015 |
| 20150299260 | POLYPEPTIDE EXPRESSED IN THE STRATUM CORNEUM AND USE THEREOF - Polypeptides belonging to the family of late proteins of the cornified envelope (LCE), fragments of the polypeptide, isolated nucleotide sequences encoding the polypeptides, and cosmetic and/or pharmaceutical compositions containing such polypeptides are described. The polypeptides have cosmetic and/or therapeutic use to reinforce the barrier function of the epidermis, prevent and/or treat the signs of skin dryness and prevent and/or treat disorders of the barrier function or the weakening of the epidermis. | 10-22-2015 |
| 20150320743 | INJECTABLE COMBINATION OF ADRENERGIC RECEPTOR AGONISTS WITH FILLERS, FOR DECREASING SKIN REACTIONS DUE TO INJECTION - The present invention concerns an injectable composition comprising a filler or a botulinum toxin and an adrenergic receptor agonist, and its use for diminishing, decreasing or avoiding skin reactions due to injection, specially redness, ecchymosis, bruising, bleeding, erythema, oedema, necrosis, ulceration, swelling and/or inflammation. | 11-12-2015 |
| 20150353605 | SHORT BIO-ACTIVE PEPTIDES FOR PROMOTING WOUND HEALING - Peptides having four to six amino acid residues are disclosed that possess biological activity. These peptides constitute short fragments of the peptide HB-107 (MPKEKVFLKIEKMGRNIRN), which itself is a fragment of the antimicrobial protein cecropin B, and exhibit cell stimulatory and migratory properties. The inventive peptides comprise four to six contiguous amino acid residues located between position 11 and 16 of HB107 (MPKEKVFLKIEKMGRNIRN), namely EKMGRN. The disclosed peptides comprise a useful agent for the medical treatment of injury to the skin, such as from diabetic ulcers. The peptides also are effective in preventing and reversing skin surface damage resulting from various environmental insults Importantly, the therapeutic effects of the peptides manifest at concentrations equal to or greater than those of peptide HB-107, and thus represent a less expensive, more versatile means for developing effective therapies. Methods for the production and use of these peptides are also disclosed. | 12-10-2015 |
| 20160002308 | MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR-DERIVED PEPTIDE AND COMPOSITION CONTAINING SAME - The present invention provides small peptide fragments derived from microphthalmia-associated transcription factor (MITF) and a pharmaceutical composition for preventing or treating melanoma comprising the same as an active ingredient. And also, the present invention provides a cosmetic composition for skin-whitening and/or for inhibiting skin pigmentation, comprising the peptide fragments as an active ingredient. | 01-07-2016 |
| 20160030322 | Applications of Surfactin in Cosmetic Products - Surfactin is a biosurfactant produced by | 02-04-2016 |
| 20160074302 | Skin Care Product and Method of Use - A cosmetic skin care product that includes an applicator and a skin care composition. The applicator includes a uni-directional magnetic array with a pitch of between 1.7 and 2.5 and a magnetic field strength of between about 24.0 and 36.0 mT. The skin care composition includes palmitoyl-lysine-threonine-threonine-lysine-serine and a dermatologically acceptable carrier. The magnetic array is tailored to enhance penetration of the Pal-KTTKS into skin during application of the skin care composition. The applicator may include a second magnetic array juxtaposed on a first magnetic array to form a bi-directional array that enhances penetration of the Pal-KTTKS into skin. | 03-17-2016 |
| 20160101032 | PEPTIDE WITH ANTI-AGING EFFECT AND USE THEREOF - An object of the present invention to discover a short peptide having an anti-aging effect and to provide a novel anti-aging agent comprising the peptide as an active ingredient. The inventors have discovered that a peptide consisting of an amino acid sequence ELKLIFLHRLKRLRKRLKRK (SEQ ID NO: 1) or a partial sequence thereof and having one or more effects selected from the group consisting of promoting fibroblast growth, promoting hyaluronic acid production and contracting a collagen gel, or a derivative or salt of the peptide is useful as an active ingredient of an anti-aging agent. | 04-14-2016 |
| 20160113852 | SEX HORMONE-BINDING GLOBULIN FOR USE AS A MEDICAMENT - Sex hormone-binding globulin and/or any fragment thereof for use as a medicament, in particular for use in the treatment of obesity and hepatic steatosis. The invention also relates to the cosmetic use of the sex hormone-binding globulin and/or any fragment thereof for improving the bodily appearance of a mammal with subcutaneous fat herniated or accumulated within the fibrous connective tissue under the skin, in particular the cosmetic use is for cellulite. | 04-28-2016 |
| 20160113853 | OLEANOYL PEPTIDE COMPOSITION AND SKIN HYDRATION - Disclosed is the a method of effecting skin hydration and enhancing skin barrier function, said method comprising the step of bringing into contact a pentapeptide conjugate of oleanolic acid with skin cells so that the effect of increased cellular communication at the molecular level to bring about gene and protein expression in the cells of the skin that enable hydration and skin barrier functions are realized. | 04-28-2016 |
| 20160374920 | TOPICAL AGENT FOR TRANSDERMAL ADMINISTRATION - The present invention aims to provide a cyclosporine external preparation showing improved transdermal absorbability of cyclosporine. The present invention provides an external preparation containing cyclosporine and a ketone. | 12-29-2016 |
