| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514200700 | Staphylococcus (e.g., Staphylococcus aureus, etc.) | 71 |
| 20100249041 | COMPOSITIONS COMPRISING ORNITHINE KETOGLUTARATE (OKG) - Suggested are new compositions comprising Ornithine Ketoglutarate (OKG) and a cosmetically acceptable carrier the latter selected from the group consisting of aliphatic alcohols or polyols having 2 to 15 carbon atoms or oil bodies. | 09-30-2010 |
| 20100249042 | COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS - The fullness and length of eyelashes and eyebrows can be enhanced by topical application of a composition comprising at least one peptide copper complex to an area of skin at the base of the eyelashes and eyebrows. Disclosed are compositions and methods for such treatment. | 09-30-2010 |
| 20100298235 | Epithelial cell growth promoter - It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof. | 11-25-2010 |
| 20110021444 | COMPOSITIONS FOR CONTROLLING HAIR GROWTH - FP-1 is a protein that is specifically expressed in the follicular papilla of the hair follicle. The nucleic acid and amino acid sequences of FP-1, as well as antibodies that specifically bind FP-1 are provided. In addition, methods of isolating follicular papilla cells and methods of modulating hair growth are also disclosed. | 01-27-2011 |
| 20110201562 | FORMULATIONS AND METHOD FOR TREATING BALDNESS - The present invention includes 1) a novel formulation for the treatment of hair loss comprising oleanolic acid (a 5α-reductase inhibitor), apigenin (a vasodilator), and biotinyl-GHK (a cell metabolism stimulant), 2) a novel additive for the treatment of hair loss comprising oleanolic acid, apigenin, biotinyl-GHK and a delivery agent, 3) a personal care, cosmetic, and/or dermopharmaceutical composition comprising oleanolic acid, apigenin, biotinyl-GHK, and at least one additional ingredient, and 4) a method for treating hair loss comprising the administration of oleanolic acid, apigenin, and biotinyl-GHK. | 08-18-2011 |
| 20120165270 | INHIBITION OF HAIR FOLLICLE GROWTH BY THE WNT INHIBITOR DKK1 - The invention provides methods of inhibiting hair growth in a post-natal subject by contacting a matured hair follicle cell with a DKK polypeptide. The inhibitory mechanism induced by a DKK polypeptide results in a reversible, transient inhibition of hair growth. | 06-28-2012 |
| 20120214746 | USE OF A COMPOSITION COMPRISING A NON-FERMENTED RICE PEPTIDE HYDROLYZATE FOR STIMULATING HAIR GROWTH - The present invention relates to the use of a composition comprising at least one non-fermented rice peptidic hydrolyzate as an active agent for slowing down and limiting hair loss and/or stimulating hair growth. Said composition is also intended to protect the follicular adult stem cells as well as their specific microenvironment. In addition, the composition according to the invention combats the aging and particularly the photoaging of hair. Lastly, the present invention relates to several non-therapeutic treatment methods utilizing said composition. | 08-23-2012 |
| 20120220541 | USE OF YEAST PEPTIDE HYDROLYSATE AS AN ACTIVE AGENT FOR STRENGTHENING HAIR - The invention concerns the use of a composition comprising at least one yeast ( | 08-30-2012 |
| 20120329726 | Hair Shape Susceptibility Gene - A genetic polymorphism and a hair shape susceptibility gene that are related to hair shape, and a method for determining the genetic susceptibility to hair shape in individual test subjects are provided. Disclosed is a hair shape susceptibility gene, which overlaps with a haplotype block in 1q21.3 region (D1S2696 to D1S2346) of human chromosome 1 and comprises a portion or the entirety of the base sequence of the haplotype block, wherein the haplotype block is determined by a linkage disequilibrium analysis conducted on a single nucleotide polymorphism (SNP) marker whose allele frequency differs statistically significantly between a group having a curly hair trait and a group having a non-curly hair trait, and consists of a base sequence set forth in any one of SEQ ID NO: 1 to NO: 5. | 12-27-2012 |
| 20130109631 | AGENT FOR GROWING, RESTORING AND REGENERATING HAIR AND METHOD OF PRODUCING A PREPARATION CONTAINING THE SAME | 05-02-2013 |
| 20130225504 | USE OF A CORN PEPTIDIC HYDROLYZATE AS AN ACTIVE AGENT STIIMULATING HAIR GROWTH - The invention relates to a cosmetic treatment method intended to stimulate hair growth, restore hair growth, and/or limit hair loss. The cosmetic treatment method includes providing a composition comprising at least one corn ( | 08-29-2013 |
| 20130331342 | SYSTEMS AND METHODS FOR IDENTIFYING COSMETIC AGENTS FOR HAIR/SCALP CARE COMPOSITIONS - Provided are methods and systems for determining functional relationships between a cosmetic agent and a hair biology condition of interest. Also provided are methods and systems for identifying cosmetic agents that affect a hair biology condition, as well as the use of agents identified by such methods and systems for the preparation of cosmetic compositions, personal care products, or both. | 12-12-2013 |
| 20140024603 | Method for Enhancing the Growth and Fullness of Hair - New fibroblast growth factor receptor 1 (FGFR1) inhibitors have been identified which are useful for promoting the retention and/or growth of keratin fibers, such as hair of the scalp, hair of the face (moustache, beard, etc.), eyebrows, eyelashes, and the like. The FGFR1 inhibitors may be formulated in effective amounts in a variety of cosmetic and personal care products. | 01-23-2014 |
| 20140349947 | HAIR GROWTH AGENT (EMBODIMENTS) AND METHOD FOR HAIR REGROWTH - The invention relates to the field of cosmetology, in particular to the hair regrowth, to the compositions of sodium salts of unfractionated heparins, to the lipid and peptide nanocomplexes for external use, to the methods for inducing and/or stimulating hair growth and/or reducing loss of hair using these compositions in the area of hair loss. | 11-27-2014 |
| 20140364378 | METHOD AND PHARMACEUTICAL COMPOSITION FOR HAIR GROWTH - The present disclosure relates to a method and a pharmaceutical composition for hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to an interest. | 12-11-2014 |
| 20150105330 | ACTIVE MIXTURES - Suggested is an active mixture comprising
| 04-16-2015 |
| 20150148300 | METHOD AND PHARMACEUTICAL COMPOSITION FOR HAIR GROWTH - The present disclosure relates to a method and a pharmaceutical composition for hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to a party of interest. | 05-28-2015 |
| 20160074470 | METHOD FOR PROMOTING HAIR GROWTH - The present disclosure relates to a method of applying a pharmaceutical composition for promoting hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to a party of interest. | 03-17-2016 |
| 20160081903 | METHOD FOR PROMOTING HAIR GROWTH - The present disclosure relates to a method of applying a pharmaceutical composition for promoting hair growth. The pharmaceutical composition includes a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1. The method includes administering a hair growth peptide (HGP) which includes all or part of the amino acid sequence SEQ ID No: 1 to an interest. | 03-24-2016 |
| 20100323951 | ANTIBACTERIAL PEPTIDES ACTIVE IN SYSTEMIC INFECTIONS - Antimicrobial peptides of the formula are provided: X | 12-23-2010 |
| 20110021415 | ANTIMICROBIAL PEPTIDES - The present invention relates to peptides comprising amino acids according to Formula I | 01-27-2011 |
| 20110028386 | Antimicrobial Peptides - Disclosed are antimicrobial peptides with useful or superior properties such as antimicrobial activity, desirable levels of hemolysis, and advantageous therapeutic index against various microorganisms, especially | 02-03-2011 |
| 20110046040 | Microorganism-inactivating agent - With a microorganism-inactivating agent comprising a composition containing γ-polyglutamic acid and/or cross-linked product of γ-polyglutamic acid; a calcium ion donor; a sodium ion donor; and an aluminum ion donor, microorganisms in water are inactivated. By further including one or more selected from microbiostatic agents and microbicides into the microorganism-inactivating agent, various microorganisms in water are inactivated to a level at which the water is suitable for drinking. | 02-24-2011 |
| 20110077193 | Artemisinin Derivatives with Natural Amino Acids, Peptides, and Amino Sugars for the Treatment of Infection and Topical Condition in Mammals - The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars, and isomers and salts thereof (formula I). The compounds of the present invention possess wide-spectrum antibacterial and antifungal biological activity suitable for topical or oral application for the treatment of infections and topical ailments in mammals, including acne, rosacea, topical wounds, infections, dandruff, skin disfigurements caused by infection, skin discoloration, age spots, wrinkles, excess facial oil, and veterinary problems including canine infections; | 03-31-2011 |
| 20110105386 | USE OF ANTIMICROBIAL POLYMERS FOR RE-SENSITIZATION OF MICROORGANISMS UPON EMERGENCE OF RESISTANCE TO ANTI-MICROBIAL AGENTS - Methods and compositions for treating microbial infections associated with an emergence of resistance of a pathogenic microorganism to an antimicrobial agent, following treatment with antimicrobial agent are disclosed. The methods are effected by using a polymer which exhibits antimicrobial re-sensitizing activity, for re-sensitizing the pathogenic microorganisms to the antimicrobial agent, in combination with the antimicrobial agent. Further disclosed are novel polymers having an antimicrobial re-sensitizing activity. | 05-05-2011 |
| 20110130326 | DEFENSINS FOR TREATMENT OF INFECTIVE ENDOCARDITIS - The present invention relates to methods for treating infective endocarditis, such as bacterial endocarditis, with defensin polypeptides. | 06-02-2011 |
| 20110152176 | AGR-MEDIATED INHIBITION AND DISPERSAL OF BIOFILMS - The present invention involves the use of activators of bacterial agr quoroum-sensing systems to block, inhibit or reverse biofilm formation. The biofilm may be located on an industrial or medical surface, or may be located in a subject, such as in a wound or infected organ, or on an in-dwelling medical device. | 06-23-2011 |
| 20110160124 | ANTIMICROBIAL PROTEIN COMPOSITIONS AND PRODUCTION THEREFOR FROM MARINE BACTERIA - Several bacterial species were isolated from marine segment obtained from seabed sediment at depths exceeding 1700 feet. At least four of the bacteria produced a compound that showed antibacterial activity against one or more multiple-drug-resistant (MDR) bacteria isolated from hospitals and clinics. One isolate, SJCH-12, exhibited a broad range of activity against MDR strains tested, including methicillin resistant | 06-30-2011 |
| 20110245153 | Neutralizing Agents for Bacterial Toxins - Stabilized variable regions of the T cell receptor and methods of making the same using directed evolution through yeast display are provided. In one embodiment, the variable region is variable beta. In one embodiment, the stabilized T cell receptor variable regions have high affinity for a superantigen, such as TSST-1 or SEB. These T cell receptor variable regions are useful as therapeutics. | 10-06-2011 |
| 20110257078 | ANTIBACTERIAL COMBINATION THERAPY FOR THE TREATMENT OF GRAM POSITIVE BACTERIAL INFECTIONS - There is described a composition comprising a therapeutically active imidazole, and derivatives thereof, and an agent active on a bacterial cell surface selected from the group consisting of one or more of colistin, nisin, D-cycloserine, fosfomycin, fosfomycin trometamol, fosfomycin disodium and polymixin B, and derivatives thereof. | 10-20-2011 |
| 20110294721 | ANTIMICROBIAL PEPTIDES - The present invention relates to a peptide comprising or consisting of a sequence of formula I A-B-C-D-E-F-G-H-I (formula I), wherein A is a peptide consisting of three or four basic amino acid residues; B is a peptide consisting of two to four hydrophobic amino acid residues; C is an amino acid residue selected from the group consisting of hydrophobic and basic amino acid residues; D is a peptide consisting of two hydrophobic amino acid residues; E is an amino acid residue selected from the group consisting of hydrophobic and basic amino acid residues; F is a peptide consisting of three amino acid residues selected from the group consisting of glycine and hydrophobic amino acid residues; G is an amino acid residue selected from the group consisting of hydrophobic and basic amino acid residues; H is a peptide consisting of two or three amino acid residues selected from the group consisting of serine and hydrophobic amino acid residues; I is a peptide consisting of two to four basic amino acid residues; or a peptidomimetic thereof, wherein the basic amino acid residues are selected from the group consisting of arginine, lysine and histidine; wherein the hydrophobic amino acid residues are selected from the group consisting of leucine, alanine, isoleucine, valine and phenylalanine; and wherein said peptide or peptidomimetic has antimicrobial and/or antiviral activity. Furthermore, the invention relates to a nucleic acid molecule encoding the peptide of the invention, a vector comprising the nucleic acid molecule as well as a host cell comprising the nucleic acid molecule or the vector. The present invention also relates to a method for producing the peptide of the invention, a composition comprising the peptide or peptidomimetic of the invention as well as to the peptide or peptidomimetic of the invention for use in treating infectious diseases. | 12-01-2011 |
| 20110294722 | ANTIMICROBIAL PEPTIDES - The present invention relates to a peptide comprising or consisting of a sequence of the formula A-B-C-D-E-F (formula I), wherein A is a peptide consisting of three to six basic amino acid residues; B is an amino acid residue or a peptide consisting of two amino acid residues, wherein said residue(s) are hydrophobic amino acid residues; C is a basic amino acid residue or is absent; D is a peptide consisting of two hydrophobic amino acid residues or is absent; E is a peptide consisting of two basic amino acid residues; and F is a peptide consisting of two hydrophobic amino acid residues; or a peptidomimetic thereof; wherein the basic amino acid residue is selected from the group consisting of arginine, lysine and histidine; wherein the hydrophobic amino acid residue is selected from the group consisting of leucine, alanine, valine, phenylalanine, isoleucine and methionine; and wherein said peptide or peptidomimetic has antimicrobial activity. Furthermore, the invention relates to a nucleic acid molecule encoding the peptide of the invention, a vector comprising the nucleic acid molecule as well as a host cell comprising the nucleic acid molecule or the vector. The present invention also relates to a method for producing the peptide of the invention, a composition as well as to the peptide or peptidomimetic of the invention for use in treating infectious diseases. | 12-01-2011 |
| 20110294723 | Compounds - The present disclosure relates to compounds of formula (II): | 12-01-2011 |
| 20110312876 | Method of determining types I, II, III, IV or V or methicillin-resistant staphylococcus aureus (MRSA) in a biological sample - Disclosed are diagnostic methods for determining a subtype of methicillin-resistant | 12-22-2011 |
| 20120015873 | MELANOCORTIN ANALOGS WITH ANTIMICROBIAL ACTIVITY - The present invention finds application in the therapeutic fields. In particular, it concerns new synthetic melanocortin peptides having improved antimicrobial activity. | 01-19-2012 |
| 20120040888 | ANTI-INFECTIVE HYDROXY-PHENYL-BENZOATES AND METHODS OF USE - The invention provides a method for preventing or treating a disease caused by an extracellular microorganism, said method comprising systemically administering to a subject in need thereof a prophylactically or therapeutically effective amount of a salicylic acid (SAL) or a SAL analogue. The extracellular microorganism can be of the bacterial genus | 02-16-2012 |
| 20120108499 | PEPTOID COMPOUNDS - The invention relates to new peptoid compounds of formula (I), as well as their use in the treatment of bacterial infections, such as those caused by vancomycin resistant microorganisms, and to compositions thereof. | 05-03-2012 |
| 20120196791 | COMBINATION THERAPIES USING ANTIBACTERIAL AMINOGLYCOSIDE COMPOUNDS - Methods for treating a bacterial infection in a mammal in need thereof, and compositions related thereto, are disclosed, the methods comprising administering to the mammal an effective amount of an antibacterial aminoglycoside compound and a second antibacterial agent. | 08-02-2012 |
| 20120202736 | SPRAY-DRIED COLLECTIN COMPOSITIONS AND PROCESS FOR PREPARING THE SAME - The present invention relates to a spray-dried composition comprising as an active ingredient at least one member protein of the collectin family or its functional equivalent for treating and preventing microbial infectious diseases. The present invention also relates to a method for producing the same composition. The composition produced by the method of the present invention is effective in suppressing infections caused by viruses, bacteria, fungi, and parasites. Since the composition is developed in a form suitable for inhalation, it can directly provide the active ingredient to the sites of infection from these microbes, and thus treat and prevent respiratory infections and external wounds. | 08-09-2012 |
| 20120289456 | ANTIMICROBIAL PROTEIN COMPOSITIONS AND USES THEREOF - Several bacterial species were isolated from marine segment obtained from seabed sediment at depths exceeding 1700 feet. At least four of the bacteria produced a compound that showed antibacterial activity against one or more multiple-drug-resistant (MDR) bacteria isolated from hospitals and clinics. One isolate, SJCH-12, exhibited a broad range of activity against MDR strains tested, including methicillin resistant | 11-15-2012 |
| 20120295839 | METHOD OF TREATMENT AND PROPHYLAXIS OF BACTERIAL VAGINOSIS - Methods of treatment or prophylaxis of bacterial vaginosis, prevention of recurrence of bacterial vaginosis and alleviation or prevention of symptoms or diagnostic criteria of bacterial vaginosis are provided. The methods include administration of an effective amount of a macromolecule comprising a polylysine, polyamidoamine, poly(etherhydroxyamine) or poly(propyleneimine) dendrimer and one or more sulfonic acid containing moieties attached thereto. | 11-22-2012 |
| 20130053305 | PEPTIDE COMPOUNDS THAT CAN BE USED AS ANTIBACTERIAL AGENTS - Compounds of formula (I), where: R | 02-28-2013 |
| 20130102524 | Compounds And Their Use - The present invention relates to peptides and their use in the treatment of microbial infections, in particular bacterial infections. In particular, the invention relates to peptides wherein at least 75% of the amino acids of the peptide are arginine and phenylalanine amino acids, at least 50% of the amino acids being arginine amino acids and at least 15% of the amino acids being phenylalanine amino acids. | 04-25-2013 |
| 20130137630 | FORMULATIONS FOR INFUSION OF TYPE B LANTIBIOTICS - Described is a A liquid colloidal pharmaceutical formulation of a type B lantibiotic for infusion or direct injection comprising a type B lantibiotic or a salt thereof, an isotonic aqueous solution comprising a sugar alcohol such as glycerol and/or a saccharide and optionally a buffer, wherein said final formulation for infusion or direct injection is clear of visual particulates. | 05-30-2013 |
| 20130203654 | NOVEL CYCLIC PEPTIDE COMPOUND, METHOD FOR PRODUCING SAME, ANTI-INFECTIVE AGENT, ANTIBIOTIC-CONTAINING FRACTION, ANTIBIOTIC, METHOD FOR PRODUCING ANTIBIOTIC, ANTIBIOTIC-PRODUCING MICROORGANISM, AND ANTIBIOTIC PRODUCED BY SAME - Provided are: a novel compound having a structure different from that of existing drugs; a novel microorganism capable of producing the novel compound; and further; a novel compound effective to a multiple-drug-resistant bacterium. To provide a novel compound having a high therapeutic effect which can be expected to have a low hurdle for practical realization by selecting an intended compound from many candidate compounds based not only on an antibacterial activity but also on evaluation including a therapeutic effect, a cyclic peptide compound shown by the following formula (1) or a pharmaceutically allowable salt thereof and a microorganism with Accession No. NITE BP-870 or a microorganism mutated naturally or artificially therefrom are provided. | 08-08-2013 |
| 20130244929 | BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS - The present invention provides novel lipoglycopeptide compounds which are Type 1 signal peptidase inhibitors (SpsB). Compounds of the present invention are useful for the treatment of various bacterial related infectious diseases, particularly when used as a potentiator of a β-lactam antibiotic such as imipenem and ertapenem. Accordingly, the present invention provides a method for the treatment of bacterial related infections using the compounds described herein, either alone or in combination with a β-lactam antibiotic. | 09-19-2013 |
| 20130267458 | COMPOSITIONS AND USES OF MATERIALS WITH HIGH ANTIMICROBIAL ACTIVITY AND LOW TOXICITY - Improved synthetic copolypeptide antimicrobials contain cationic amino acid residues and may be based on a blocky sequence. These antimicrobials show low mammalian toxicity and may undergo directed self-assembly. The inventive synthetic copolypeptides are useful in treatment of wounds and other infections. | 10-10-2013 |
| 20130288952 | Polypeptides and Immunizing Compositions Containing Gram Positive Polypeptides and Methods of Use - The present invention provides isolated polypeptides isolatable from a | 10-31-2013 |
| 20130310307 | METHODS AND COMPOSITIONS FOR TREATMENT OF MULTIDRUG-RESISTANT BACTERIAL AND FUNGAL INFECTIONS - The invention provides a method of killing an infectious microbe by administering an effective amount of transferrin to an individual having a microbial infection, wherein the transferrin has microbicidal activity, thereby reducing survival of the infectious microbe in the individual. The invention also provides a method of prophylactically treating an individual to decrease the likelihood of contracting a microbial infection, comprising administering an effective amount of transferrin to an individual, wherein the transferrin has microbicidal activity, thereby decreasing the likelihood that the individual will contract a microbial infection. The invention still further provides a method of treating septicemia by administering an effective amount of transferrin to an individual in need thereof, thereby treating the individual. | 11-21-2013 |
| 20140038883 | NOVEL AZACOUMARIN DERIVATIVES HAVING MDR PUMP INHIBITING ACTIVITY - The present invention relates to compounds of formula (I), where R | 02-06-2014 |
| 20140073558 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS - The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against | 03-13-2014 |
| 20140087997 | ANTI-MICROBIAL PEPTIDES AND USES OF SAME - A method of treating a bacterial infection in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of a peptide being between 3 and 5 amino acids, wherein at least one amino acid of said 3 and 5 amino acids is selected from the group consisting of tryptophan, cysteine, proline and methionine. | 03-27-2014 |
| 20140235531 | ANTIMICROBIAL PEPTIDES FOR TREATMENT OF INFECTIOUS DISEASES - The present invention is directed to the peptides WKWLKKWIK, WRKFWKYLK, and RRWRVIVKW and use of said peptides as therapeutic agents for the prophylaxis and/or treatment of infections, in particular bacterial and/or fungal infections and diseases caused by bacterial and/or fungal infections. | 08-21-2014 |
| 20140256615 | PEPTIDE-BASED QUORUM SENSING INHIBITORS FOR THE ATTENUATION OF VIRULENCE IN STAPHYLOCOCCUS AUREUS - Compounds that affect quorum sensing (QS) in | 09-11-2014 |
| 20140274879 | METHODS OF USE FOR AN ANTIMICROBIAL PEPTIDE - The present invention encompasses methods for treating an infection and/or treating or reducing inflammation through the administration of a therapeutically effective amount of a peptide to a subject in need thereof. In some aspects, the peptide is a | 09-18-2014 |
| 20140303072 | Method of Determining Types I, II, III, IV or V or Methicillin-resistant Staphylococcus aureus (MRSA) in a Biological Sample - Disclosed are diagnostic methods for determining a subtype of methicillin-resistant | 10-09-2014 |
| 20140315788 | METHODS FOR IMPROVING HEART FUNCTION - The present invention encompasses combination comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and/or muscle function. | 10-23-2014 |
| 20140315789 | ANTIMICROBIAL PEPTIDES AND USES THEREOF - The present disclosure relates generally to antimicrobial peptides, methods for their use, and methods for preparing devices having surfaces which are modified to incorporate OH said peptides. In some embodiments, the antimicrobial peptides are antimicrobial OH cationic peptides modified to comprise a thiol functional group. | 10-23-2014 |
| 20140323391 | BIOMARKERS FOR THE MOLECULAR CLASSIFICATION OF BACTERIAL INFECTION - Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject. | 10-30-2014 |
| 20140329739 | ANTIBIOTIC PEPTIDE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREFOR - Disclosed are an antibiotic peptide and the like, having an amino acid sequence of Ac-Phe-Lys-Lys-Leu-Lys-Lys-Leu-Phe-Ser-Lys-Leu-Trp-Asn-Trp-Lys-NH | 11-06-2014 |
| 20140329740 | ANTI-INFECTIVE HYDROXY-PHENYL-BENZOATES AND METHODS OF USE - The invention provides a method for preventing or treating a disease caused by an extracellular microorganism, said method comprising systemically administering to a subject in need thereof a prophylactically or therapeutically effective amount of a salicylic acid (SAL) or a SAL analogue. The extracellular microorganism can be of the bacterial genus | 11-06-2014 |
| 20150011465 | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME - Novel peptoid oligomers are disclosed that have a formula represented by the following formula I: | 01-08-2015 |
| 20150038407 | OLIGOPEPTIDE COMPOUNDS AND USES THEREOF - The present invention relates to novel agents, pharmaceutical compositions containing them, and theft use in therapy, particularly anti-microbial and anti-cancer therapy. In particular, the present invention relates to novel peptide-based compounds based on SEQ ID NO: 40 which have surprisingly been shown to have inhibitory effects on the growth and/or viability of cells, particularly bacterial and cancer cells. Also provided are therapeutic and non-therapeutic methods which include the use of peptides of the invention. | 02-05-2015 |
| 20150065415 | PRODRUG DERIVATIVES OF (E)-N-METHYL-N-((3-METHYLBENZOFURAN-2-YL)METHYL)-3-(7-OXO-5,6,7,8-TETRAHY- DRO-1,8-NAPHTHYRIDIN-3-YL)ACRYLAMIDE - In part, the present disclosure is directed to prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide compounds with significant solubility and bioavailability profiles. | 03-05-2015 |
| 20150080291 | SHORT ANTIMICROBIAL LIPOPEPTIDES - Disclosed are peptides having biological and therapeutic activity. Particularly disclosed are lipidated di- or tri-peptides analogs of KPV or KdPT that exhibit antimicrobial activity. In particular, the peptides of this invention provide enhanced anti-microbial activity over the base tri-peptides, lysine-proline-valine and lysine-d-proline-tyrosine. The disclosed peptides have the general formula of C12-18 lipid-KXZ-NH | 03-19-2015 |
| 20150099694 | IDENTIFICATION AND SUSCEPTIBILITY OF MICROORGANISMS BY SPECIES AND STRAIN - Devices, systems, and methods for strain-specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a colorimetric sensor array to metabolic products of the microorganism. | 04-09-2015 |
| 20150290273 | METHODS FOR TREATMENT OF SKIN AND SKIN APPENDAGES WITH A LINSEED EXTRACT AS AN ACTIVE AGENT ACTIVATING THE SYNTHESIS OF ANTIMICROBIAL PEPTIDES - Methods for the treatment of irritations of the skin and skin appendages caused by microbial stresses are disclosed. The methods include providing a composition comprising a linseed extract, obtained from hydrolysis of linseed proteins, as an active antimicrobial agent in a physiologically acceptable medium, and topically applying the linseed extract onto the skin in need thereof. The methods may be useful in the cosmetic and pharmaceutical field and, more particularly, in the field of dermatology. Cosmetic methods for reinforcing the chemical barrier function of healthy and/or sensitive skin and skin appendages are also disclosed that include the same or similar composition and steps. | 10-15-2015 |
| 20150290281 | METHODS AND DEVICES FOR BONE INFECTION TREATMENT SELECTION - Disclosed are methods for identifying patients at increased risk of developing disseminated staphylococcal infection, which includes the steps of determining that the patient has a mutation in one or more genes selected from a MPDZ network gene, a CGNL1 network gene, a PRKRIR network gene, a MED26 network gene, a tight junction protein gene, or an immune modulator gene; and treating the patient for disseminated staphylococcal infection. Also disclosed are solid substrates and/or assays useful for carrying out the disclosed methods. | 10-15-2015 |
| 20150297673 | NOVEL ANTI-BIOTIC PEPTIDE ORIGINATED FROM RIBOSOMAL PROTEIN L1 OF HELICOBACTER PYLORI AND USE OF THE SAME - The present invention relates to a novel antibiotic peptide originated from the ribosomal protein L1 of | 10-22-2015 |
| 20150337011 | DENDRIMERIC PEPTIDES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME - Novel peptide compounds and pharmaceutical compositions thereof are disclosed that have a formula represented by the following formula (I) wherein L | 11-26-2015 |
| 20150344527 | ANTIMICROBIAL PEPTIDES, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF - Antimicrobial peptides such as, for example, the peptides shown in SEQ ID No 1, SEQ ID No 2, SEQ ID No 3, SEQ ID No 4 or SEQ ID No 5. The peptides have activity against Gram positive bacteria and against Gram negative bacteria. A bactericidal composition is also provided, which may comprise an amount between 0.5 μg/mL and 1024 μg/mL of the peptides; and excipients. | 12-03-2015 |
| 20150366931 | FERMENTED CATIONIC PEPTIDE-BASED ANTIMICROBIAL EXTRACT COMPATIBLE WITH ANIONIC COMPOUNDS - An antimicrobial composition compatible with anionic compounds is prepared by a process of contacting a cationic peptide-based antimicrobial extract with an ion exchange resin. | 12-24-2015 |
| 20160022832 | PROTEAS STABILIZED ANTIBACTERIAL PEPTIDES FOR S. AUREUS - Improved peptide compositions and synbody compositions are disclosed that show improved stability and antibiotic activity. The new antibacterial peptides for | 01-28-2016 |
| 20160039881 | SITE-SELECTIVE FUNCTIONALIZATION OF GLYCOPEPTIDE ANTIBIOTICS - Site-selective functionalized glycopeptide antibiotics, methods of making and using are described herein. The compounds exhibit improved activity against methicillin-susceptible | 02-11-2016 |
| 20160052978 | ANTIMICROBIAL PROTEIN - The inventors provide a composition comprising an antimicrobial polypeptide comprising Blad or an active variant thereof for use in a method of treatment of the human or animal body by therapy or prophylaxis, such as for use in a method of treating or preventing an infection in or on a subject by a microorganism. Also provided is the use of a composition comprising an antimicrobial polypeptide comprising Blad or an active variant thereof to kill, or inhibit the growth of, a microorganism that is pathogenic to a human or an animal at a site that is not on or in the human or animal body. | 02-25-2016 |
| 20160082146 | COMPOSITION FOR USE IN WOUND HEALING IN BURNS - The preset invention relates to a new method for wound healing, particularly in burns, comprising Epinecidin-1 (Epi-1) or Pardaxin (GE33), optionally in the incorporation into collagen. | 03-24-2016 |
| 20160095313 | ANTIMICROBIAL COMPOSITIONS AND METHODS - The present invention is generally related to a product and process to reduce the microbial contamination on organic matter, such as processed meat, fruits and vegetables, plant parts, inanimate surfaces such as textiles and stainless steel, and in the mouth or on dental products. In particular, the invention is related to a product and process to disinfect surfaces using an antimicrobial composition containing an antimicrobial lipid, an enhancer selected from the group consisting of bacteriocins, antimicrobial enzymes, sugars, sugar alcohols, iron-binding proteins and derivatives thereof, siderophores, and combinations thereof, and optionally a surfactant. | 04-07-2016 |
| 20160101148 | TREATMENT AND PREVENTION OF BACTERIAL SKIN INFECTIONS USING ORITAVANCIN - Methods for the treatment and prevention of bacterial skin infections using the glycopeptide antibiotic oritavancin are disclosed. | 04-14-2016 |
| 20160120883 | ANTI-INFECTIVE HYDROXY-PHENYL-BENZOATES AND METHODS OF USE - The invention provides a method for preventing or treating a disease caused by an extracellular microorganism, said method comprising systemically administering to a subject in need thereof a prophylactically or therapeutically effective amount of a salicylic acid (SAL) or a SAL analogue. The extracellular microorganism can be of the bacterial genus | 05-05-2016 |
| 20160130301 | NOVEL PEPTIDE AND USES THEREOF - This present invention provides a novel peptide for inhibiting growth of microorganisms, a pharmaceutical composition, an antimicrobial composition comprising such novel peptide, and a method for inhibiting growth of microorganisms. The novel peptide for inhibiting growth of microorganisms has amino acid sequence: KX | 05-12-2016 |
| 20160158169 | Antimicrobial Compositions with Cysteamine - The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections. | 06-09-2016 |
| 20160158312 | POLYPEPTIDES AND IMMUNIZING COMPOSITIONS CONTAINING GRAM POSITIVE POLYPEPTIDES AND METHODS OF USE - The present invention provides isolated polypeptides isolatable from a | 06-09-2016 |
| 20160177297 | ANTISENSE MOLECULES FOR TREATMENT OF STAPHYLOCOCCUS AUREUS INFECTION | 06-23-2016 |
| 20160194360 | PEPTIDE-BASED QUORUM SENSING INHIBITORS FOR THE ATTENUATION OF VIRULENCE IN STAPHYLOCOCCUS AUREUS | 07-07-2016 |
| 20160200769 | Compound, Transitmycin, Effective Against Bacterial and Viral Pathogens | 07-14-2016 |
| 20160200771 | ANTIBACTERIAL AGENTS: SALINAMIDE DERIVATIVES | 07-14-2016 |
| 20160376306 | N-Terminally Modified Linear and Branched Polyamine Conjugated Peptidomimetics as Antimicrobials Agents - N-terminally modified linear and branched polyamine conjugated peptidomimetics as antimicrobials agents. The invention relates to therapeutically viable antibacterial compositions based on ultra short mimetic of host defense cationic peptides (HDCPs). The invention relates to template based N-terminal modified di-peptidomimetics with or without modifications in polyamine backbone as new antibacterial agents. Most active peptidomimetics were bactericidal and caused a rapid decrease in viability of broad range of Gram-positive and Gram-negative bacterial strains in low micromolar concentration range including activity against clinically relevant pathogen methicillin resistant | 12-29-2016 |
| 20160376322 | Derivative Peptide Compounds and Methods of Use - The present invention provides synthetic peptide compounds and uses thereof for therapy and diagnostics of complement-mediated diseases, such as inflammatory diseases, autoimmune diseases, and microbial and bacterial infections; and non-complement-mediated diseases, such cystic fibrosis and various acute diseases. The invention is directed to modifications of a synthetic peptide of 15 amino acids from the Polar Assortant (PA) peptide, which is a scrambled peptide derived from human Astrovirus protein. In some embodiments, the invention is directed to peptide compounds that are peptide mimetics, peptide analogs and/or synthetic derivatives of PA (e.g., sarcosine derivatives) having, for example, internal peptide substitutions, and modifications, including PEGylation at the N-terminus and C-terminus. The invention further provides methods of selecting at least one synthetic peptide for treating various conditions. | 12-29-2016 |
| 20180020660 | BIOFILM INHIBITOR | 01-25-2018 |
| 20190142892 | CHEMOSYNTHETIC CYCLO-HEPTA MODIFIED PEPTIDE CAPABLE OF INHIBITING TOXIN OF STAPHYLOCOCCUS AUREUS AND USE THEREOF | 05-16-2019 |
