| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 800020000 | Fish | 32 |
| 20080320610 | Transgenic fish with increased unsaturated fatty acid content - The present invention relates to fish with increased unsaturated fatty acid content by transfer of a fatty acid desaturase gene thereinto, and a production method of these fish with increased unsaturated fatty acid content. The fatty acid desaturase gene is one or more members selected from among Δ4 fatty acid desaturase gene, Δ5 fatty acid desaturase gene and Δ6 fatty acid desaturase gene, and it is preferable that these genes originate in a freshwater fish. It is preferable that the expression of a fatty acid desaturase gene originating in a freshwater fish is promoted by a β-actin promoter originating in medaka. By modifying the fatty acid metabolic pathway of fish, problems to be solved by the present invention may be to provide fish having a high vitality and a tolerance to handling and low temperature, which will enable the use of a vegetable fat or animal fat as a formula feed. Such vegetable fat is less expensive and can be easily controlled in qualities, thereby largely contributing to the reduction of cost and labor in fish nursery sites. | 12-25-2008 |
| 20090077681 | Methods for Diagnosing and Treating Heart Disease - The invention provides methods of diagnosing heart disease, such as heart failure, methods for identifying compounds that can be used to treat or to prevent heart disease, and methods of using these compounds to treat or to prevent heart disease. Also provided in the invention are animal model systems that can be used in screening methods. | 03-19-2009 |
| 20090113565 | Methods for Detecting Fluorescent Proteins and Animals Having Fluorescent Proteins - Provided are methods for detecting expression of nucleic acids encoding mutant fluorescent proteins. In the methods, a nucleic acid encoding a mutant fluorescent protein, or a full complement thereof, is introduced into a cell or organism. The cell or organism is allowed to replicate. Expression of the nucleic acid is detected by emission of fluorescent light. Animals including a nucleic acid encoding a mutant fluorescent protein, or a full complement thereof, are also provided. | 04-30-2009 |
| 20090133138 | NEW GENE FRAGMENT, NOVEL TRANSGENIC ZEBRAFISH AND METHODS FOR PRODUCING TRANSGENIC ZEBRAFISH - The present invention provides a method for producing systemic red fluorescent zebrafish. The present invention also provides a new gene fragment and a systemic red fluorescent zebrafish. | 05-21-2009 |
| 20090133139 | NUCLEOTIDE SEQUENCE OF SHRIMP ACTIN PROMOTER AND ITS USE IN GENETIC TRANSFORMATION BIOTECHNOLOGY - The present invention relates to an isolated β-actin nucleic acid promoter molecule from shrimp; nucleic acid constructs including the β-actin promoter molecule; and expression vectors, host cells, and transgenic animals transduced with the isolated β-actin nucleic acid promoter. Also disclosed are methods for imparting to an animal resistance against a pathogen, regulating growth of an animal, increasing stress tolerance in an animal, and increasing cold tolerance in an animal that involves transforming an animal with a nucleic acid construct including the isolated β-actin nucleic acid promoter molecule of the present invention. | 05-21-2009 |
| 20090144841 | Polymorphisms in the human gene for the multidrug resistance-associated protein 1 (MRP-1) and their use in diagnostic and therapeutic applications - The present invention relates to a polymorphic MRP-1 polynucleotide. Moreover, the invention relates to genes or vectors comprising the polynucleotides of the invention and to a host cell genetically engineered with the polynucleotide or gene of the invention. Further, the invention relates to methods for producing molecular variant polypeptides or fragments thereof, methods for producing cells capable of expressing a molecular variant polypeptide and to a polypeptide or fragment thereof encoded by the polynucleotide or the gene of the invention or which is obtainable by the method or from the cells produced by the method of the invention. Furthermore, the invention relates to an antibody which binds specifically the polypeptide of the invention. Moreover, the invention relates to a transgenic non-human animal. The invention also relates to a solid support comprising one or a plurality of the above mentioned polynucleotides, genes, vectors, polypeptides, antibodies or host cells. Furthermore, methods of identifying a polymorphism, identifying and obtaining a pro-drug or drug or an inhibitor are also encompassed by the present invention. In addition, the invention relates to methods for producing of a pharmaceutical composition and to methods of diagnosing a disease. Further, the invention relates to a method of detection of the polynucleotide of the invention. Furthermore, comprised by the present invention are a diagnostic and a pharmaceutical composition. Even more, the invention relates to uses of the polynucleotides, genes, vectors, polypeptides or antibodies of the invention. Finally, the invention relates to a diagnostic kit. | 06-04-2009 |
| 20090255005 | Method for Preparing Fish Embryo - An object of the invention is to effectively prepare a fish embryo with a correct chromosomal ploidy by nuclear transplantation in which an exogenous fish nucleus is transplanted in a cytoplasmic recipient. For this object, the invention comprises a step of preparing a fish embryo by transplanting a fish cell nucleus to an unfertilized egg. The step of preparing a fish embryo comprises a step of imposing physical and/or chemical stress to the unfertilized egg after activation. By imposing such stress, the stage of haplosis in a female nucleus which happens at the early stage of a series of developmental steps occurring in an unfertilized egg is suppressed and the correct ploidy of an obtained embryo is at least secured. | 10-08-2009 |
| 20090255006 | Transgenic Zebrafish - Transgenic zebrafish containing sqt genomic sequences driving expression of a reporter gene are provided. This line faithfully reproduces the spatiotemporal expression pattern of endogenous sqt, and at the late blastula stage is expressed in the YSL as well as in the blastomeres. The data show that expression in embryonic and extra-embryonic tissues is controlled by separable regulatory elements, including at least two elements that mediate the response to Nodal signals in different cell types. An element upstream of the transcription start site mediates the response to Nodal signaling specifically in the EVL cells. By contrast, a conserved Nodal response element (NRE) in the first introns is required for transgene expression in the blastomeres. The data show that expression of the transgene in the blastomeres depends on Nodal signaling activity. Furthermore, expression of sqt and cyc in the blastomeres depends upon Nodal signals from the YSL. These experiments suggest that Nodal signals in the YSL act to induce nodal-related gene expression in the embryo margin by activating the Nodal autoregulatory pathway. Targeted depletion of Nodal signals from the YSL results in embryos lacking endoderm and head mesoderm, similar to the defects observed in mice lacking Nodal function in the visceral endoderm. Thus, the data provides strong genetic evidence for the functional conservation between the YSL and the visceral endoderm. This suggests a common evolutionary origin for teleost and mammalian extra-embryonic tissues, despite their profound morphological differences. | 10-08-2009 |
| 20100037330 | Efficient Somatic Cell Nuclear Transfer In Fish - The present disclosure provides methods of producing enucleated cells by photoablation. Such enucleated cells may be used as recipient cells for Somatic Cell Nuclear Transfer and cloning. The nuclear donor and/or enucleated recipient cells may be any fish cells, such as zebrafish, koi, or medaka fish cells. Such methods may be used to efficiently produce transgenic fish including by way of example zebrafish, koi, and medaka fish. | 02-11-2010 |
| 20100037331 | RECOMBINANT CONSTRUCTS AND TRANSGENIC FLUORESCENT ORNAMENTAL FISH THEREFROM - The present invention relates to the method and use of reef coral fluorescent proteins in making transgenic red, green and yellow fluorescent zebrafish. Preferably, such fluorescent zebrafish are fertile and used to establish a population of transgenic zebrafish and to provide to the ornamental fish industry for the purpose of marketing. Thus, new varieties of ornamental fish of different fluorescence colors from a novel source are developed. | 02-11-2010 |
| 20100050280 | RECOMBINANT CONSTRUCTS AND TRANSGENIC FLUORESCENT ORNAMENTAL FISH THEREFROM - The present invention relates to the method and use of reef coral fluorescent proteins in making transgenic red, green and yellow fluorescent zebrafish. Preferably, such fluorescent zebrafish are fertile and used to establish a population of transgenic zebrafish and to provide to the ornamental fish industry for the purpose of marketing. Thus, new varieties of ornamental fish of different fluorescence colors from a novel source are developed. | 02-25-2010 |
| 20100212038 | TRANSGENIC FISH WITH TISSUE-SPECIFIC EXPRESSION - Disclosed are transgenic fish, and a method of making transgenic fish, which express transgenes in stable and predictable tissue- or developmentally-specific patterns. The transgenic fish contain transgene constructs with homologous expression sequences. Also disclosed are methods of using such transgenic fish. Such expression of transgenes allow the study of developmental processes, the relationship of cell lineages, the assessment of the effect of specific genes and compounds on the development or maintenance of specific tissues or cell lineages, and the maintenance of lines of fish bearing mutant genes. | 08-19-2010 |
| 20100212039 | INFERTILITY CONTROL OF GENETICALLY MODIFIED FISH - A method of inducing male and/or female infertility in a genetically modified (GM) fish is disclosed. Also disclosed is a method of generating an infertile GM fish with a phenotype and/or genotype of interest. The method involves generation of a GM fish whose genome comprises a foreign transgene operably linked to a fish gonad-specific promoter selected from the group consisting of an ovary-specific promoter and a testis-specific promoter. The transgene comprises a suicide gene selected from the group consisting of a reductase and a photosensitizer, in which the reductase is operably linked to a reporter gene. Infertility of the GM fish is induced if the GM fish expressing the reductase is treated with an effective amount of a reductase-activated cytotoxic prodrug or if the GM fish expressing the photosensitizer is treated with light irradiation. | 08-19-2010 |
| 20110099648 | RECOMBINANT GENE WHICH ENHANCES THE ABILITY OF FISH TO TOLERATE LOW DISSOLVED OXYGEN STRESS AND THE USE THEREOF - The invention discloses a recombinant gene which enhances the ability of fish to tolerate low dissolved oxygen (DO) stress and the use thereof. Carp β-actin gene promoter is used as a promoter and | 04-28-2011 |
| 20110239318 | METHODS FOR PRODUCING FISH WITH HIGH LIPID CONTENT - The invention provides methods for producing biofuel from algae, that use fish which have a high capacity of producing and/or accumulating lipids to harvest algae from an algal culture. The invention also provides methods for growing fish that result in a high lipid content. The invention also provides methods for creating fish that have a high capacity of producing and accumulating lipids by breeding and/or recombinant DNA techniques. Also included are transgenic fish that have a higher lipid content than wild-type fish. | 09-29-2011 |
| 20120167241 | CHIMERIC GENE CONSTRUCTS FOR GENERATION OF FLUORESCENT TRANSGENIC ORNAMENTAL FISH - Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5′ end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed. | 06-28-2012 |
| 20120210453 | PURPLE TRANSGENIC FLUORESCENT ORNAMENTAL FISH - The present invention relates to the method and use of fluorescent proteins in making purple transgenic fluorescent fish. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. Thus, new varieties of ornamental fish of different fluorescence colors from a novel source are developed. | 08-16-2012 |
| 20120210454 | BLUE TRANSGENIC FLUORESCENT ORNAMENTAL FISH - The present invention relates to transgenic blue ornamental fish, as well as methods of making such fish by in vitro fertilization techniques. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. | 08-16-2012 |
| 20120233716 | NOVEL FATTY ACID ELONGASE AND USES THEREOF - The present invention relates to nucleic acids derived from Sphaeroforma arctica. The invention also relates to the individual coding sequences and to proteins encoded by these sequences in combination with other sequences as well as to a process for converting oleic acid to linoleic acid to linoleic acid and the production of arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid in a plant. | 09-13-2012 |
| 20120240248 | Novel Fatty Acid Desaturase and Uses Thereof - The present invention relates to nucleic acids derived from | 09-20-2012 |
| 20120260358 | APTAMER CAPABLE OF BINDING TO VIRAL HEMORRHAGIC SEPTICEMIA VIRUS - A pharmaceutical and a method for preventing and treating VHSV infection in fish with a VHSV-binding aptamer is provided. Also provided are a method for removing VHSV from an area of water and a method and kit for detecting VHSV with high sensitivity using a VHSV-binding aptamer. | 10-11-2012 |
| 20120304322 | METHOD FOR ACQUIRING GENETICALLY IDENTICAL GAMETE FROM LETHAL FISH HAPLOID-DERIVED GERM CELL VIA GERM LINE CHIMERA - Disclosed are a method for acquiring a germ line chimeric fish having fish haploid germ cells, a germ line chimeric fish having haploid germ cells obtained by the aforesaid method, and a genetically identical gamete, said gamete having been derived from a donor haploid germ cell, produced by a germ line chimeric fish obtained by the aforesaid method. | 11-29-2012 |
| 20120317665 | Recombinant Constructs And Purple Transgenic Fluorescent Ornamental Fish Therefrom - The present invention relates to the method and use of fluorescent proteins in making purple transgenic fluorescent fish. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. Thus, new varieties of ornamental fish of different fluorescence colors from a novel source are developed. | 12-13-2012 |
| 20120317666 | Blue Transgenic Fluorescent Ornamental Fish - The present invention relates to transgenic blue ornamental fish, as well as methods of making such fish by in vitro fertilization techniques. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. | 12-13-2012 |
| 20130133093 | RECOMBINANT CONSTRUCTS AND TRANSGENIC FLUORESCENT ORNAMENTAL FISH THEREFROM - The present invention relates to the method and use of reef coral fluorescent proteins in making transgenic red, green and yellow fluorescent zebrafish. Preferably, such fluorescent zebrafish are fertile and used to establish a population of transgenic zebrafish and to provide to the ornamental fish industry for the purpose of marketing. Thus, new varieties of ornamental fish of different fluorescence colors from a novel source are developed. | 05-23-2013 |
| 20130333060 | GREEN TRANSGENIC FLUORESCENT ORNAMENTAL FISH - The present invention relates to transgenic green ornamental fish, as well as methods of making such fish by in vitro fertilization techniques. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. | 12-12-2013 |
| 20140007265 | CHIMERIC GENE CONSTRUCTS FOR GENERATION OF FLUORESCENT TRANSGENIC ORNAMENTAL FISH | 01-02-2014 |
| 20140033338 | GREEN TRANSGENIC FLUORESCENT ORNAMENTAL FISH - The present invention relates to transgenic green ornamental fish, as well as methods of making such fish by in vitro fertilization techniques. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. | 01-30-2014 |
| 20140130195 | ORANGE TRANSGENIC FLUORESCENT ORNAMENTAL FISH - The present invention relates to transgenic fluorescent orange ornamental fish, as well as methods of making such fish by in vitro fertilization techniques. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. | 05-08-2014 |
| 20150096067 | FEED FOR FISH - A fish feed includes carvacrol and/or salvia extract (provided that where the fish feed comprises carvacrol and not salvia extract the lipid content of the fish feed is at least 15 wt %). The salvia extract may be selected from extract of | 04-02-2015 |
| 20160113252 | TILAPIA (OREOCHROMIS NILOTICUS) MYOSIN LIGHT CHAIN 3 PROMOTER - The preset invention relates to a promoter to target a fluorescent protein to the muscles of fish, such as | 04-28-2016 |
| 20160128310 | BLUE TRANSGENIC FLUORESCENT ORNAMENTAL FISH - The present invention relates to transgenic blue ornamental fish, as well as methods of making such fish by in vitro fertilization techniques. Also disclosed are methods of establishing a population of such transgenic fish and methods of providing them to the ornamental fish industry for the purpose of marketing. | 05-12-2016 |
