Class / Patent application number | Description | Number of patent applications / Date published |
623230760 | Having means to promote cellular attachment | 18 |
20080249639 | Medical Artificial Nerve Graft Containing Silk Fibroin and Its Preparation Method - A medical artificial nerve graft containing silk fibroin used in bridging of nerve damage and its preparation method. The medical artificial nerve graft comprised of vessel or comprised of vessel and fibre scaffold, wherein at least one of the vessel and the fibre scaffold contains component of silk fibroin, and the wall of the vessel has three-dimensional structure provided with numerous microaptures. The preparation method includes the following steps: silk is used to prepare silk fibre; the silk fibroin fibre is used to prepare the vessel or the fibre scaffold containing silk fibroin; and combining the fibre scaffold with the vessel i.e. inlaying the fibre scaffold into the vessel and so on. | 10-09-2008 |
20080269910 | Medical prosthetic devices having improved biocompatibility - The invention relates to a medical prosthetic device having a metal material, such as titanium or an alloy thereof, where the surface parts of the metal material are coated with a layer of a corresponding hydroxide material, such as titanium hydroxide. Preferably, the hydroxide layer includes one or more biomolecule substances associated therewith. The invention also relates to an electrolytic process for the preparation of a medical prosthetic device. | 10-30-2008 |
20090030528 | DEVICES AND METHODS FOR TREATING DEFECTS IN THE TISSUE OF A LIVING BEING - An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may include, or have blended in, an additive, such as an osteoinductive factor, for example biocompatible ceramics and glass. | 01-29-2009 |
20090043400 | DEVICES AND METHODS FOR TREATING DEFECTS INTHE TISSUE OF A LIVING BEING - An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. | 02-12-2009 |
20090048685 | Method And Apparatus For Occluding A Lumen - A method and apparatus of occluding a lumen of a body cavity, more preferably, the lower uterine segment and/or cervix of a female patient is provided that results in a significant reduction or complete elimination of uterine bleeding, thereby providing a treatment option for conditions such as menorrhagia or dysmenorrhea. | 02-19-2009 |
20090105843 | Method for Bonding a Titanium Based Mesh to a Titanium Based Substrate - A method for metallurigically bonding a metal wire mesh to a metal substrate which allows the use of a fragile open weave mesh and/or a thin wall substrate. A thin nickel based layer is placed between a titanium based substrate and a titanium based wire mesh. The mesh and substrate are lightly clamped in intimate contact against the nickel interlayer therebetween, e.g., by wire wrapping. The sandwich, or assembly, (i.e., substrate, interlayer, mesh) is then heated to a temperature, below the melting point of titanium and nickel but sufficient to form a eutectic titanium-nickel alloy (e.g. , Ti | 04-23-2009 |
20100057219 | DEVICE SURFACE DESIGN FOR BETTER CELL ADHESION - Embodiments herein relate to devices promoting cell adhesion and methods of making thereof In some embodiments, one or more insoluble or non-degradable second surface components are positioned over one or more soluble or degradable first surface components over a surface. The first surface components can be degraded or dissolved to produce bumps or raised portions formed from the second surface components on the surface. | 03-04-2010 |
20100082114 | TISSUE REPAIR IMPLANT - Described herein are tissue repair implants comprising at least a first layer of peritoneal membrane. The first layer of peritoneal membrane can be located adjacent to a second layer of peritoneal membrane and can be in direct contact with the second layer of peritoneal membrane. Additional layers (e.g., a third or fourth layer) can be included. Where more than one layer is present, the layers can be affixed to one another. For example, a first layer of peritoneal membrane can be attached to the second layer of peritoneal membrane by an adhesive bond, suture, or staple. One or more of the peritoneal membranes can be non-crosslinked, partially crosslinked, or substantially fully crosslinked. Any of the layers of peritoneal membrane may be attached to a wall (e.g., an interior or exterior wall) of an abdominal tissue by an adhesive, suture, and/or staples. | 04-01-2010 |
20100211184 | Magnetic implants and methods for treating an oropharyngeal condition - Magnetic devices and implantation methods are provided for use in the treatment of obstructive sleep apnea. The devices include a sheet-like element having ferromagnetic qualities. The device may also include a permanent magnet attached to the sheet-like element by magnetic forces. The devices are implanted in soft tissue surrounding the airway and in tissue space beneath the pharyngeal wall to exert forces on and/or change the shape of the soft tissue. The magnetic devices may also include a bladder containing a magnetorheological fluid that stiffens soft tissue when exposed to a magnetic field. | 08-19-2010 |
20100318193 | TOPOGRAPHICALLY ENGINEERED STRUCTURES AND METHODS FOR USING THE SAME IN REGENERATIVE MEDICINE APPLICATIONS - The present invention provides compositions including a cell contacting surface or film comprising nanotopography of nanofibers, nanotubes, nanochannels, microchannels or microwells, which are capable of enhancing or promoting cell differentiation or cell viability. The compositions are useful as medical implants, including orthopedic implants, dental implants, cardiovascular implants, neurological implants, neurovascular implants, gastrointestinal implants, muscular implants, and ocular implants. The present invention also provides methods of treating a patient in need of such an implant. | 12-16-2010 |
20120253474 | PLATFORM FOR SOFT TISSUE ATTACHMENT - One embodiment of the implant comprises a porous metal bone ingrowth portion ( | 10-04-2012 |
20120310368 | Surgical Implant - A surgical implant comprising: a substrate having an exterior surface and a plurality of layers disposed over the substrate exterior surface. The substrate comprises a polymeric material, and the plurality of layers comprises: an activated substrate surface layer; a valve metal layer; and a porous valve metal oxide layer, wherein the valve metal layer is disposed between the activated substrate layer and the porous valve metal oxide layer. The disclosure provides for a method for producing a polymeric surgical implant. The exterior substrate surface is treated by one or more processes comprising: plasma activation; electron beam irradiation; ultraviolet light; and low energy Ar+ ion beam irradiation; producing an activated substrate surface layer. A plurality of layers is applied over the activated substrate surface layer. The surface is converted by a spark-anodization process in an alkaline bath containing Ca and P ions into a layer of porous valve metal oxide. | 12-06-2012 |
20140094932 | MATERIALS AND METHODS FOR PROTECTING AGAINST NEUROMAS - The subject invention provides devices and methods for alleviating discomfort associated with neuroma formation. The devices and methods of the invention effectively use the body's natural response of reconstructing implanted biomaterials to minimize the size of, isolate, and protect a neuroma. In preferred embodiments, the subject device is a cylindrical cap, wherein the internal chamber of the cylindrical cap physically partitions the nerve to enable an arrangement of nerve fibers (as opposed to haphazardly arranged nerve fibers often produced in neuromas). In addition, the cap's material remodels into a tissue cushion after implantation, which protects the neuroma from being stimulated and inducing pain. | 04-03-2014 |
20140114435 | TOPOGRAPHICAL FEATURES AND PATTERNS ON A SURFACE OF A MEDICAL DEVICE AND METHODS OF MAKING THE SAME - The invention relates to medical devices that has a surface configured to promote the migration of cells onto the surface of the medical device. In particular, the surface of the medical device has a noncontiguous pattern of topographical features formed therein or thereon. | 04-24-2014 |
20140114436 | MEDICAL DEVICES AND METHODS FOR IMPROVING THE BIOCOMPATIBILITY OF MEDICAL DEVICES - A medical device configured to be at least partially implanted within a host. The medical device includes an outer surface at least a portion of which is impermeable to cells but is permeable to molecules secreted by cells, the outer surface separating a space inside the medical device from a surrounding tissue of the host. The medical device also includes a diffusion sink positioned within the space and configured to cause molecules that are secreted into the tissue by immune cells during a foreign body response (FBR) to diffuse, through random motion, through the portion and into the diffusion sink. | 04-24-2014 |
20150018969 | Drug-Impregnated Encasement - A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity configured to receive the medical implant. In one embodiment, the biologically-compatible material is bioresorbable. The body may include a plurality of apertures, such as perforations or holes, extending from the cavity through the body. The sleeve may further include a first end, a second end, and a drug impregnated into the resorbable sheet. In one possible embodiment, the first end of the sleeve may be open for receiving the medical implant therethrough and the second end may be closed. The implant may be encased in the sleeve and implanted into a patient from which the drug is dispensed in vivo over time to tissue surrounding the implantation site. In one embodiment, the body is made from at least one sheet of a biologically-compatible material. | 01-15-2015 |
20150374477 | POROUS DEVICES AND PROCESSES FOR PRODUCING SAME - A method for making a polymer with a porous layer from a solid piece of polymer is disclosed. In various embodiments, the method includes heating a surface of a solid piece of polymer to a processing temperature and holding the processing temperature while displacing a porogen layer through the surface of the polymer to create a matrix layer of the solid polymer body comprising the polymer and the porogen layer. In at least one embodiment, the method also includes removing at least a portion of the layer of porogen from the matrix layer to create a porous layer of the solid piece of polymer. | 12-31-2015 |
20160008513 | TONSILLECTOMY SPONGE | 01-14-2016 |