| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 623230580 | Polymers | 30 |
| 20080249633 | Biodegradable Materials and Methods of Use - The present invention provides novel and inventive biodegradable and biocompatible materials and methods of use in biomedical area. Inventive materials can be formed by blending PLGA with ACP or any one of their family members. Inventive materials can be used in making biodegradable products including but not limit to drug eluting stents, vascular graft, bone substitutes such as bone fixation screws, surgical sutures and anti-adhesive membranes, and/or drug-slow release control vehicle etc. | 10-09-2008 |
| 20080262631 | Method For Providing a Polymeric Implant With a Crystalline Calcium Phosphate Coating - This invention relates to a method for crystallizing an amorphous calcium phosphate (Cap) by high energy laser light irradiation. The method is particularly suited for crystallizing CaP coatings on polymeric substrates, particularly implant objects. | 10-23-2008 |
| 20080306609 | Fixation of Elastomer to Rigid Structures - A surgical implant, especially an artificial intervertebral disc, includes a rigid substrate ( | 12-11-2008 |
| 20100076572 | DEVICE AND METHOD FOR RECONSTRUCTION OF OSSEOUS SKELETAL DEFECTS - A synovial joint implantable apparatus for the reconstruction of skeletal defects with a flexible member, which is preferably resorbable, attached to a rigid structural prosthesis such as a total hip or total knee replacement implant. The cavitary space defined and surrounded by the flexible member is filled with osteoconductive and/or inductive materials which eventually matures into new column of bone. The prosthesis is supported by the bed of graft material surrounding it and is gradually unloaded as the bed matures into solid bone. The fixation of the prosthesis into native bone depends on the specific implant and the anatomic area of its use. The flexible member is secured to the margins of the prosthesis using rails, runners, sutures, or other attachment devices that prevent the escape of the bone graft and maintain an initial column of support for the implant. Should the metal implant even need removal, the reconstituted bone can be separated from the implant in such a way as to restore bone stock and facilitate future revision surgical procedures. | 03-25-2010 |
| 20100262259 | PROCESS FOR PRODUCING BONE GRAFTING MATERIAL, BONE GRAFTING MATERIAL, THREE-DIMENSIONAL SUPPORT FOR CELL CULTURE, AND SEPARATION SUPPORT FOR CHROMATOGRAPHY - A novel method for producing a bone filling material is provided. The method comprises the steps of: (a) kneading ingredient comprising calcium-based material and material comprising binder; (b) molding a predetermined shape of the mixture obtained in step (a) with an injection molding machine having a mold; (c) removing the binder contained in the mold formed in step (b) (i.e., degreasing) to obtain a degreased body; (d) and heating and sintering the degreased body obtained in step (c) to obtain a sintered body. | 10-14-2010 |
| 20110282464 | Reactive Surgical Implants - The present disclosure relates to a sprayable surgical implant. The implant includes a first component including microparticulates and a second component including at least one cross-linking reagent. The at least one cross-linking reagent reacts with the microparticulates to form the surgical implant. | 11-17-2011 |
| 20120022665 | POLYMER SLIDING MATERIAL, ARTIFICIAL JOINT MEMBER, MEDICAL APPLIANCE, AND MANUFACTURING METHOD THEREFOR - Disclosed is a sliding member with excellent durability and capable of maintaining wear resistance over a long period of time. Further disclosed is an artificial joint member for which the film thickness of the polymer base material is reduced. Further disclosed is an artificial joint which is capable of demonstrating high lubricity, biocompatibility, and resistance to dislocation after introduction into the body. Further disclosed are a medical appliance material and a medical appliance which demonstrate excellent biocompatibility. The sliding material or the medical appliance material is formed by a polymer layer or a biocompatible material layer (B) being provided by coating at least a portion of the surface of a polymer base material (A), the surface of which has a ketone group, and the polymer layer or biocompatible layer (B) is characterized by being formed by surface graft polymerization, wherein the polymer base material (A) is immersed in a reaction system which contains a monomer (C), the polymer base material (A) is exposed to light, and polymerization of the monomer is initiated from the surface of the polymer base material (A). Using the sliding material or medical appliance material, an artificial joint member, an artificial joint, a medical appliance material, and a medical appliance are manufactured. | 01-26-2012 |
| 20120035741 | SELF-EXPANDABLE BIOPOLYMER-MINERAL COMPOSITE - A compressed implant composite for repairing mineralized tissue. The compressed implant composite includes a matrix formed of biopolymeric fibers and a plurality of calcium- and/or silicate-based mineral particles dispersed in the matrix. The matrix constitutes 4 to 80% by weight and the mineral particles constitute 20 to 96% by weight of the composite. The composite is free of soluble collagen and is expandable to a volume 2 to 100 times of its compressed volume (e.g., upon absorption of water). Also disclosed are methods of preparing the above-described composite. | 02-09-2012 |
| 20120101593 | IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS - A solidifying implant composition of a polymer mixed with a bioabsorbable solvent. A method of treating a patient, by implanting the solidifying implant composition into bone, and solidifying the implant composition. A method of improving bone structure in patients by applying the solidifying implant composition to bone, shoring up bone structure, and improving load bearing capacity and aiding healing of microfractures. A method of fixing an implant, by applying the solidifying implant composition to an implant, and shoring up the implant. A method of devascularizing and treating a tumor or vascular lesion. A method of treating a vascular disease. A method of treating aneurysms/pseudoaneurysms. | 04-26-2012 |
| 20120323339 | POROUS PEEK ARTICLE AS AN IMPLANT - The present invention refers to a porous PEEK-type polymer article comprising a porous PEEK-type polymer structure and presenting at least a trimodal pore distribution. The invention describes a process for the production of said porous PEEK-type polymer article comprising: a) contacting a PEEK-type polymer with a composition comprising at least a organic solvent, b) heating at a temperature at which the PEEK-type polymer is dissolved, c) adding at least a porogen agent, d) cooling the mixture obtained in c) at a temperature at least equal or lower than the temperature at which the PEEK-type polymer precipitates, e) forming said cooled mixture into a shaped article, f) removing the organic solvent and the porogen agent, and g) recovering the PEEK-type polymer article. | 12-20-2012 |
| 20130190891 | BONE DELIVERY SYSTEM - A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be formed of polymers for providing extended shelf life and/or increased moisture and radiation resistance, and may include a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust the release of the substance. In various embodiments, the covering may be formed of a biocompatible material and is suitable for a variety of procedure specific uses. | 07-25-2013 |
| 20130211541 | Porous Implant Materials and Related Methods - Provided are porous, biocompatible implant bodies and materials. These materials suitably comprise a population of randomly arranged thermoplastic constituents, with at least some of the constituents being bonded to one another The implant bodies are capable of being manipulated at room temperature from a first shape to a second shape, and of maintaining the second shape at about internal body temperature. Also provided are related methods of fabricating such implants and installing the implants into a subject. | 08-15-2013 |
| 20130226311 | WEDGE APPARATUS FOR USE IN OPERATING ON A BONE - An implantable device includes a polymeric body and a metallic first mounting strip connected to a trailing end portion of the body. The body has a leading end portion, a first side surface, a second side surface, an upper surface, a lower surface and a central opening extending through the upper and lower surfaces. The central opening has an internal surface with an internal leading surface, a first internal side surface and a second internal side surface. A first depth is defined between the leading end and the internal leading surface, a first spacing is defined between the first side surface and the first internal side surface and a second spacing is defined between the second side surface and the second internal side surface. The first spacing is substantially the same as the second spacing and the first depth is less than the first spacing. | 08-29-2013 |
| 20130310948 | POROUS METAL STRUCTURES MADE FROM POLYMER PREFORMS - The present disclosure relates to porous orthopedic implants made from polymer preforms and a method of manufacturing the same. A polymer material may be formed into a preform, such as by an injection molding process or an additive manufacturing process. In an exemplary embodiment, the overall shape and the porous framework of the preform is predetermined to be substantially the same as the overall shape and the porous framework of the final orthopedic implant. Then, the preform may be pyrolyzed and coated with metal to form the final orthopedic implant. | 11-21-2013 |
| 20130338790 | NON-WOVEN FABRIC CONTAINING BONE PROSTHETIC MATERIAL - An object of the present invention is to provide a bone regeneration material suitable for bone (in particular, alveolar bone) regeneration. The present invention provides a non-woven fabric containing a bone prosthetic material wherein the bone prosthetic material is included between biocompatible fibers that constitute the non-woven fabric. The non-woven fabric may be suitably used as a bone regeneration material (in particular, a dental bone regeneration material). | 12-19-2013 |
| 20130345826 | Implants for Bone and Cartilage Repair - An implant for the repair of bone and cartilage that includes a cell conductive zone that contains biopolymeric fibers and an osteoconductive zone that contains biopolymeric fibers and calcium-containing mineral particles. The biopolymeric fibers from one zone overlaps with the fibers in the other zone forming a stable physical and mechanical integration of the two zones thus conferring in vivo stability to the implant. | 12-26-2013 |
| 20130345827 | ORTHOPEDIC IMPLANT WITH POROUS POLYMER BONE CONTACTING SURFACE - The present disclosure relates to orthopedic implants including a porous, non-metallic, bone interface or outer bone contacting surface adapted for promoting bone ingrowth into the pores of such surface. The present disclosure also relates to orthopedic implants having a porous, non-metallic and/or polymeric bone interface or outer bone contacting surface wherein the implant has a stiffness that approaches or substantially matches the stiffness of the surrounding bone and thereby reduces the effects of stress shielding. The present disclosure also relates to methods of making such implants. | 12-26-2013 |
| 20140046454 | FRACTURE FIXATION SYSTEMS - Systems and methods for bone fracture repair are disclosed. One system includes a biocompatible putty that may be packed about a bone fracture to provide full load-bearing capabilities within days. The disclosed putties create an osteoconductive scaffold for bone regeneration and degrade over time to harmless resorbable byproducts. | 02-13-2014 |
| 20140074252 | EXPANDABLE IMPLANT - An implant system includes a fixation device that, in turn can include an expandable implant alone or in combination with an auxiliary implant. The expandable implant includes an expandable implant body that is made from an expandable material. The expandable material includes a polymer matrix and an expandable gas source contained within at least a portion of the polymer matrix. The implant system can further include an energy source configured to heat the polymer matrix to a temperature above its glass transition temperature, thereby causing the gas source to expand inside the polymer matrix. The fixation device can further include an insertion instrument configured to implant the fixation device into an anatomical cavity. | 03-13-2014 |
| 20140128990 | BONE PUTTY - The present invention relates to a macroporous material for filling bone voids. In particular, we describe an implant material comprising bioresorbable polymer granules and a biocompatible water-miscible solvent, wherein the solvent at least partially dissolves and/or softens the polymer granules to form a mouldable mass that can be used to fill a bone defect but hardens when water is added and/or the implant material is placed in an aqueous environment, and wherein the implant material has macroporosity suitable for bone in-growth. | 05-08-2014 |
| 20140277572 | Ultrafine Electrospun Fibers of Poly-4-Hydroxybutyrate and Copolymers Thereof - Methods to produce structures containing ultrafine fibers with average diameters from 10 nm to 10 μm and more preferably from 50 nm to 5 μm, have been developed. These methods produce ultrafine fibers without substantial loss of the polymer's weight average molecular weight. The ultrafine electrospun fibers have an unexpectedly higher degree of molecular orientation, and higher melt temperature than fibers derived by dry spinning. In the preferred embodiment, the polymer comprises 4-hydroxybutyrate. The ultrafine fibers are preferably derived by electrospinning. A solution of the polymer is dissolved in a solvent, pumped through a spinneret, subjected to an electric field, and ultrafine fibers with a high degree of molecular orientation are collected. These structures of ultrafine fibers can be used for a variety of purposes including fabrication of medical devices. | 09-18-2014 |
| 20140350692 | Biomineralization Promoting Materials and Methods of Forming Same - Bone tissue biomimetic materials, biomimetic constructs that can be formed with the materials, and methods for forming the materials and constructs are described. The bone tissue biomimetic materials include electrospun nanofibers formed of polymers that are conjugated with peptides that include acidic amino acid residues. The materials can incorporate high levels of mineralization so as to provide mechanical strength and promote osteogenesis and/or osteoconductivity on/in the bone tissue biomimetic materials. The materials and constructs can be utilized in forming tissue engineered structures for in vitro and in vivo use. Macroscopic bone tissue biomimetic scaffolds formed from the materials can be seeded with osteogenic cells and utilized to develop bone graft materials that can exhibit strength and osteoconductivity similar to the native bone and that exhibit uniform distribution of nutrients in the scaffolds. | 11-27-2014 |
| 20150327893 | COMPOSITE MATERIAL BONE IMPLANT - A composite bone implant. In some embodiments, one or more features are provided, such as markers for passageways, axial engagement of bone screws, sliding support of bone screws and/or a cannulated channel for a guide wire. | 11-19-2015 |
| 20160067375 | 3D BIOMIMETIC, BI-PHASIC KEY FEATURED SCAFFOLD FOR OSTEOCHONDRAL REPAIR - This invention describes methods for the creation of 3D biologically inspired tissue engineered scaffolds with both excellent interfacial mechanical properties, and biocompatibility and products created using such methods. In some cases, a combination of nanomaterials, nano/microfabrication methods and 3D printing can be employed to create structures that promote tissue reconstruction and/or production. In other embodiments, electrospinning techniques can be used to create structures made of polymers and nanotubes. | 03-10-2016 |
| 20160128836 | Systems and Methods for Joint Stabilization - Photodynamic devices for stabilizing a joint are provided. In some embodiments, a photodynamic joint spacer is provided that includes an expandable member configured for attachment to a bone having an excised region; a formable bar configured for attachment to the bone along at least a portion of the expandable member; and a light-sensitive liquid passed into the expandable member to expand the expandable member, wherein the expandable member is shaped by the formable bar to a shape resembling the excised region of the bone, and wherein the light-sensitive liquid is curable upon exposure to light energy to set the expandable member in the shape resembling the excised region to form a photodynamic joint spacer. | 05-12-2016 |
| 20170231767 | Bone Graft Cage | 08-17-2017 |
| 20180021476 | MEDICAL IMPLANT | 01-25-2018 |
| 623230590 | Polymer coating | 3 |
| 20090030524 | ANTIOXIDANT DOPING OF CROSSLINKED POLYMERS TO FORM NON-ELUTING BEARING COMPONENTS - Methods provide a non-eluting antioxidant doped UHMWPE in the form of an implant bearing component. The process includes the steps of: (a) providing a preform; (b) irradiating the preform with γ-irradiation to crosslink the UHMWPE; (c) doping the crosslinked preform by exposing it to an antioxidant composition at a temperature below the melting point of the UHMWPE; (d) removing the doped material from contact with the antioxidant composition; and then (e) annealing by heating the doped material at a temperature above 30° C. and below the melting point of the UHMWPE; followed by (f) making an implant bearing component from the doped material, wherein at least 1 mm but no more than about 15 mm of material are removed to make the component. | 01-29-2009 |
| 20100249945 | SURFACE MODIFICATION OF ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENE - The present invention relates to polymers and, specifically, to surface modification of polymers. In one exemplary embodiment, the present invention increases the bond strength of UHMWPE components to PMMA bone cement by creating a chemical bond between the UHMWPE components and the PMMA bone cement. Specifically, in one exemplary embodiment, a surface of the UHMWPE component that is to be bonded to PMMA bone cement is treated with an oxidizing agent, such as an aqueous solution of hydrogen peroxide. In one exemplary embodiment, the UHMWPE component is treated with hydrogen peroxide by swabbing the surface of the UHMWPE component with the hydrogen peroxide solution. The surface of the UHMWPE component may then be dried and PMMA bone cement applied to the surface of the UHMWPE component. | 09-30-2010 |
| 20130282137 | COATED IMPLANT - An orthopedic implant comprising a metallic substrate coated with a diamond-like carbon (DLC) layer, and a layer of a polymeric material placed over the DLC layer that is less stiff than the substrate, and methods of manufacturing the same. | 10-24-2013 |
