| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 623230570 | Including bioactive coating | 23 |
| 20080255677 | Surfaces differentially adhesive to bacteria and eukaryotic cells - A surface coating comprises a primer coat that permits adhesion of eukaryotic cells thereto, and a plurality of macromolecular structures attached to the primer coat. At least some of the macromolecular structures have a cell-resistant character, meaning that cells generally will not adhere to them. The macromolecular structures are distributed across an area of the primer coat so that the surface coating permits adhesion of the eukaryotic cells to the primer layer and resists the adhesion of non-eukaryotic cells. Typically, the primer coat comprises a self-assembled polymeric monolayer and the macromolecular structures comprise nanoscale hydrogels. Such surface coatings may be formed on articles of manufacture for insertion into the body, such as orthopedic devices. | 10-16-2008 |
| 20080306608 | OSTEOCHONDRAL PLUG GRAFT, KIT AND METHOD - Each of an osteochondral plug graft and a kit comprises a trapezoid shaped construct configured for osteochondral implanting. An osteochondral regeneration method comprises forming a recipient socket in a chondral area of an articular joint in need of repair; harvesting a trapezoid shaped graft from another chondral area; and implanting the trapezoid shaped graft into the recipient socket. | 12-11-2008 |
| 20090319051 | OSTEOCHONDRAL PLUG GRAFT, KIT AND METHOD - Each of an osteochondral plug graft and a kit comprises a trapezoid shaped construct configured for osteochondral implanting. An osteochondral regeneration method comprises forming a recipient socket in a chondral area of an articular joint in need of repair; harvesting a trapezoid shaped graft from another chondral area; and implanting the trapezoid shaped graft into the recipient socket. | 12-24-2009 |
| 20100249944 | Multizone Implants - Medical devices having more than one degradation zone or degradation mechanism are used for orthopedic repair devices and soft tissue fixation devices. | 09-30-2010 |
| 20100331997 | IMPLANT FOR INTRODUCTION INTO AN ALVEOLAR SPACE - The implant is intended for introduction into an alveolar space. It is configured as an absorbable composite body made of at least a first and a second part body. The first part body is configured as a cone, truncated cone or cylinder having a body base face. The second part body is configured as a cover membrane with a membrane face, which is larger than the body base face. The cover membrane is placed on the body base face, so it projects laterally everywhere over the body base face. The first and second part body are rigidly connected to one another in the region of the mutually adjacent body base face and membrane face. | 12-30-2010 |
| 20110112654 | BONE IMPLANT APPLICATION - One arrangement in combination, a bone implant, and one or more bioactive substances which can reduce inflammation in implant surgery, preferably in the field of dentistry. The implant may also comprise one or more bioactive substance(s) that can promote osseointegration of said bone implant. At least one of said one or more bioactive substances may be capable of reducing proliferation, differentiation, and/or activity of osteoclasts, stimulating proliferation of osteoblasts, and/or reducing inflammation. | 05-12-2011 |
| 20110213468 | Silane Coating Process for High Alkali Bioactive Glasses - A method of preparing a ceramic-resin composite material for bone repair, including preparing a predetermined amount of pH controlled substantially anhydrous coupling agent by mixing a liquid silane material, alcohol and organic acid, producing particulate bioactive glass having a desired particle size of less than about 53 mesh, measuring a desired quantity of the particulate bioactive glass into a mixing vessel, heating the mixing vessel and particulate bioactive glass to about 100 degrees Celsius, mixing the heated quantity of particulate bioactive glass and spraying a predetermined amount of substantially anhydrous coupling agent into the heated quantity of particulate bioactive glass to define an admixture, mixing the admixture for sufficient time to define a quantity of substantially evenly coated particles, heating the quantity of substantially evenly coated particles for sufficient time to evolve excess solvent therefrom, and incorporating the quantity of substantially evenly coated particles into a resinous matrix to define a bone replacement medium. | 09-01-2011 |
| 20110276148 | IMPLANTABLE MEDICAL DEVICE - An implantable medical device, which comprises a device substrate, a coating on the substrate which includes a drug which is highly soluble in water, and a protective layer which overlies the coating. The protective layer comprises a polymer selected from the group consisting of polylactic acid, polyglycolic acid and a lactic acid/glycolic acid copolymer having a weight average molecular weight of not more than 40,000. | 11-10-2011 |
| 20120016489 | TEXTURED BONE BLOCK IMPLANTS - Implantable pliable bone blocks comprising a solid block of cortical bone characterized by a length, width and thickness, having a first and a second face on opposite sides of the block. The first and second faces have a plurality slot features. The angle of incidence of the slot features of the first face and the x-axis and the angle of incidence of the slot features of the second face and the x-axis (a | 01-19-2012 |
| 20120310366 | METHODS AND COMPOSITIONS TO ENHANCE BONE GROWTH COMPRISING A STATIN - Implantable medical devices and methods are provided that have one or more statins disposed therein. The medical devices may be implanted at near or in a bone defect to enhance bone growth. In some embodiments, the medical device provided allows for sustain release of the statin and facilitates bone formation and repair of the fracture site. | 12-06-2012 |
| 20130110252 | IMPLANT FOR CARTILAGE REPAIR | 05-02-2013 |
| 20130138221 | METHODS AND COMPOSITIONS FOR IMPROVING IMPLANT OSSEOINTEGRATION - The disclosed methods, uses and articles are in the field of orthopedic and dental implants. In particular, the disclosure relates to compositions and methods for improving the osseointegration of such implants. | 05-30-2013 |
| 20130166040 | REAGENTS AND METHODS FOR PREPARING TEETH FOR IMPLANTATION - The invention provides reagents and method for replacing teeth lost to periodontitis and other diseases and disorders resulting in tooth loss, and provides materials and methods that result in replacement or reimplanted teeth that have a higher rate of stable, long-term implantation status. In a first aspect, the invention provides an implantable tooth, comprising a natural or artificial animal tooth having a microporous tooth root surface, wherein said tooth root surface comprises a plurality of periodontal ligament progenitor cells coating all or a portion of the tooth root. In particular embodiments, the tooth is a natural tooth, especially a human tooth. In alternative embodiments, the tooth is an artificial tooth. In particular embodiments, the tooth comprises a periodontal ligament progenitor cell coating that further comprises one or a plurality of extracellular matrix proteins. In a second aspect, the ivnention provides kits for preparing an implantable tooth. | 06-27-2013 |
| 20130197660 | IMPLANTABLE DEVICES HAVING ANTIBACTERIAL PROPERTIES AND MULTIFUNCTIONAL SURFACES - Implantable devices having antibacterial activity for preventing periprosthetic infections and for improving osteointegration capacity are provided. Methods for making and using such devices are also provided. | 08-01-2013 |
| 20130211540 | MULTILAYER SURGICL MEMBRANE - One aspect of the present invention relates to a multilayer surgical membrane. The surgical membrane can include a substantially fluid impermeable outer layer, an inner layer that includes a plurality of fenestrae, and a middle region disposed between the inner and outer layers. The middle region can include at least one channel that extends through the middle region. The middle region can have a first surface in contact with the inner layer. The at least one channel can imbibe fluid under a compressive or tensile load and the fenestrae can deform to exude fluid under the load. | 08-15-2013 |
| 20130245783 | Implant With Antimicrobial Coating - The invention relates to an implant with a coating ( | 09-19-2013 |
| 20130282136 | METHOD FOR MODIFYING THE WETTABILITY AND OTHER BIOCOMPATIBILITY CHARACTERISTICS OF A SURFACE OF A BIOLOGICAL MATERIAL BY THE APPLICATION OF BEAM TECHNOLOGY AND BIOLOGICAL MATERIALS MADE THEREBY - A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated. | 10-24-2013 |
| 20130297038 | BONE IMPLANTS AND METHODS COMPRISING DEMINERALIZED BONE MATERIAL - Bone implant compositions and methods are provide that have an outer surface, the outer surface comprising demineralized bone and having a cavity disposed in the outer surface, the cavity having a demineralized bone material coated therein; and an inner surface of the bone implant comprising cortical bone, the inner surface contacting the outer surface. The bone implant compositions and methods provided are osteoinductive and allow rapid bone fusion. | 11-07-2013 |
| 20140222160 | METHOD OF USING MEDICAL IMPLANTS - Disclosed herein is a method of using a medical implant in a subject. The method comprises treating a medical implant with ultraviolet light (UV) in a closed environment, causing the temperature of the medical implant to be between room temperature (Rt) and about 37° C., and immediately, and placing the implant of a temperature from about the room temperature to about 37° C. in a site in need within the subject. | 08-07-2014 |
| 20140277571 | IMPLANTS WITH WEAR RESISTANT COATINGS AND METHODS - An implant comprises a substrate and a coating on a surface of the substrate, and the coating comprises silicon nitride and has a thickness of from about 1 to about 15 micrometer. A method of providing the implant comprises coating a surface of the implant substrate with the coating comprising silicon nitride and having a thickness of from about 1 to about 15 micrometer by physical vapour deposition. | 09-18-2014 |
| 20150359636 | METHOD FOR MODIFYING THE WETTABILITY AND OTHER BIOCOMPATIBILITY CHARACTERISTICS OF A SURFACE OF A BIOLOGICAL MATERIAL BY THE APPLICATION OF BEAM TECHNOLOGY AND BIOLOGICAL MATERIALS MADE THEREBY - A method of preparing a preformed bone shape for implantation provides irradiating at least a portion of a preformed bone shape by a Neutral Beam derived from a GCIB, and the preformed bone shape so irradiated. | 12-17-2015 |
| 20160158417 | DYNAMIC POROUS COATING FOR ORTHOPEDIC IMPLANT - A dynamic porous coating for an orthopedic implant, wherein the dynamic porous coating is adapted to apply an expansive force against adjacent bone so as to fill gaps between the dynamic porous coating and adjacent bone and to create an interference fit between the orthopedic implant and the adjacent bone. | 06-09-2016 |
| 20220133480 | SYSTEM AND METHOD TO FUSE BONE - Systems and methods include a method to fuse two sections of bone. The method includes various operations such as accessing the chest cavity (e.g., by severing the sternum) and preparing the sternal edges of the two sections of bone. Sternal wires are implanted around the two sections of bone to create a cradle in a space between the two sections of bone. Cancellous bone tissue may be harvested from the patient and used to hydrate an implant before trimming the implant and/or placing the implant in the cradle. The sternal wires are tightened to compress the implant between the two sections of bone; and the ends of the sternal wires are tied together to create a sternal structure comprised of the implant tightly compressed between the two sections of bone. The sternal construct can act as a bone gasket to improve healing and fusing for the two sections of bone. | 05-05-2022 |
