| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 623230510 | Composite bone | 48 |
| 20080255676 | Two piece cancellous construct for cartilage repair - The invention is directed toward a cartilage repair assembly comprising a shaped allograft two piece construct with a demineralized cancellous cap and a mineralized cylindrical base member defining a blind bore with a through going transverse bore intersecting the blind bore. The demineralized cancellous cap has a cylindrical top portion and a smaller diameter cylindrical stem extending away from the top portion which fits into the blind bore of the mineralized base member. The cap stem defines a transverse through going bore which is aligned with the through going bore of the base member to receive a cylindrical cortical pin holding the cap within the base member. The shaped structure is dimensioned to fit in a drilled bore in a cartilage defect area so that the assembly engages the side wall of the drilled bore in an interference fit. | 10-16-2008 |
| 20080288083 | Osseointegration Implant - The invention relates to an osseointegration implant having a three-dimensional structure, which at least partly covers the surface of the implant. The structure is of a latticework wherein the ratio of the volume of interstices of the latticework to the volume of the mass of the latticework is increasing towards the bone contacting face. Such a latticework matches the characteristics of natural bone and assures that the requisite amount of loading is transferred to the surrounding bone. This minimizes the stress applied to the interface between the host tissue and the implant eliminating atrophy resulting from either insufficient or excessive loading to result in both reduced surgical cost and complications associated with implantation. | 11-20-2008 |
| 20090043398 | METHOD OF PRODUCING GRADIENT ARTICLES BY CENTRIFUGATION MOLDING OR CASTING - The present invention provides a method for producing articles with a gradient of density, porosity and/or concentration by subjecting a viscous material to centrifugation during production of the article. The viscous material may be a composite material comprising a hydrogel. The viscous material can be molded or cast into the article. In certain embodiments, the viscous material is used to create an articulating surface implant such as a replacement plug, a knee spacer, or a spinal disc. The article may also be an implant such as a shoulder implant or other socket type implant that is produced by centrifuging in two axes which produces a gradient relative to both axes of rotation. | 02-12-2009 |
| 20090265016 | MATERIAL FOR SURGICAL USE IN TRAUMATOLOGY - The present invention relates to a material, structure, and method for surgical use in traumatology. More particularly, the present invention relates to a composite material, a temporary biocompatible support structure, and related methods of use of the same in aiding osteosynthesis during healing of a bone fracture. The material keeps its strength in a solid phase in vivo and, to aid removal upon healing, can be transformed into a substantially fluid phase, including, for example, a pulverized state, by the application of energy at a chosen time. | 10-22-2009 |
| 20100145468 | ARTIFICIAL BONE CAPABLE OF BEING ABSORBED AND REPLACED BY AUTOGENOUS BONE AND ITS PRODUCTION METHOD - An artificial bone capable of being absorbed and replaced by an autogenous bone, which comprises a cylindrical body obtained by rolling a sheet-shaped apatite/collagen composite, a hollow center portion of the cylindrical body penetrating from one end surface to the other end surface having a diameter of 100-1000 μm. | 06-10-2010 |
| 20100168868 | LAYERED GRADIENT MATERIAL FOR BIOLOGICAL USE AND METHOD FOR PRODUCING THE SAME - A layered gradient material which comprises a plurality of layers composed of a mixture of hydroxyapatite and calcium tertiary phosphate and is obtained by producing a layered body by stacking a plurality of layers in which the compounding ratio of hydroxyapatite to calcium tertiary phosphate is stepwise or continuously changed and then sintering the layered body by the spark plasma sintering method is excellent in mechanical strength such as compressive strength, flexural strength and Young's modulus, and further, is excellent in biological reactivity such that in the case where it is used as a bone substitute material, bone destruction and new bone reconstruction actively occur. Accordingly, it is extremely useful as a biological material such as a bone substitute material, artificial tooth root and dental cement. | 07-01-2010 |
| 20100234966 | BONE REPAIR OR AUGMENTATION DEVICE - Bone repair or augmentation devices comprising a porous body ( | 09-16-2010 |
| 20100268349 | ASSEMBLED IMPLANT - This invention is directed to an assembled implant comprising two or more portions of bone that are held together in appropriate juxtaposition with one or more biocompatible pins to form a graft unit. Preferably, the pins are cortical bone pins. Typically, the cortical pins are press-fitted into appropriately sized holes in the bone portions to achieve an interference fit. The bone portions are allograft or xenograft. | 10-21-2010 |
| 20110040388 | BIOCOMPATIBLE IMPLANT - A biocompatible implant for bone repair comprising a flexible membrane fitted around a bone defect and a platelet-rich plasma gel composition contained within the void space created by the membrane, its application and kit of parts thereof are described. | 02-17-2011 |
| 20110066253 | CERAMIC COATED ORTHOPAEDIC IMPLANTS AND METHOD OF MAKING SUCH IMPLANTS - Orthopaedic implants with scratch-, wear- and corrosion-resistant ceramic coatings on metal substrates are provided, as well as methods for making such coatings. The metal substrate is advantageously HIP'd and homogenized prior to coating with the ceramic, and the HIP'd and homogenized metal substrate is preferably ground and polished prior to coating with the ceramic. The ceramic coating may include a band with multiple thin alternating layers of titanium nitride, titanium carbonitride or both titanium nitride and titanium carbonitride, and may include an alumina overcoat. The present coatings curtail the growth of microcracks that can otherwise result from surface cracks or scratches on coated substrates, and thereby provide improved wear characteristics, scratch resistance, and prevent the penetration of corrosive fluids to the substrate material. | 03-17-2011 |
| 20110166669 | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles - Constructs that are at least partially constructed of allograft cancellous bone are disclosed, along with cartilage particles that may be used with the constructs for repairing articular cartilage defects. A multi-piece construct includes a base member, a cap member and at least one pin that secures the cap member to the base member. The base member may be constructed of mineralized cancellous bone, and is used to replace the subchondral bone removed when a surgeon cuts a bore in the area of an adjacent cartilage defect. The base member includes a blind bore and first and second through-going transverse bores in opposite sides of a wall of the base member. The cap member includes an upper section that has a thickness that is similar to that of a patient's surrounding articular cartilage layer and a stem depending from the upper section that is dimensioned to be received in and by the blind bore of the base member. The stem includes a transverse through-going bore, which may be aligned with the transverse through-going bores of the base member to receive the pin therein when the construct has been assembled. The cap member is at least partially formed of demineralized allograft cancellous bone, into which a mixture containing lyophilized, freeze-milled allograft cartilage particles may be infused for the repair of articular cartilage defects. The cartilage particles have a size within a range of from about 10 microns to about 210 microns. | 07-07-2011 |
| 20110276147 | Bone Graft Substitutes and Methods Thereof - An osteoinductive bone graft substitute composition that does not return to its original shape upon hydration or manipulation is disclosed, comprising, in combination, about 86-89% by weight of a calcium phosphate particulate mineral component and about 11-14% by weight of a purified fibrillar collagen, the mineral component including about 20% to about 60% by weight of hydroxyapatite and about 60% to about 20% by weight of tricalcium phosphate. A package configured to store a bone graft composition is disclosed, comprising an inner sterile polymeric V-shaped pouch located in an outer sterile polymeric V-shaped pouch. Methods for repairing a bone defect in a patient are disclosed using the osteoinductive bone graft substitute composition. | 11-10-2011 |
| 20120136456 | CERAMIC FOAM ARTIFICIAL BONE - A sterile artificial bone product is provided. The sterile artificial bone product comprises a sintered porous ceramic foam material having a density of 0.3 to 1.5 g/cc, and a porosity of 40 to 95%, pores of the material having a pore diameter distribution of 10-500 microns. Additionally, a bioactive compound is coupled to the ceramic foam material. Other embodiments are also described. | 05-31-2012 |
| 20120203355 | Devices and Methods for Tissue Engineering - A resorbable tissue scaffold fabricated from bioactive glass fiber forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the bioactive glass fiber in the porous matrix. Strength of the bioresorbable matrix is provided by bioactive glass that fuses and bonds the bioactive glass fiber into the rigid three-dimensional matrix. The resorbable tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue. | 08-09-2012 |
| 20120245703 | COMPOSITE BONE MATERIAL IMPLANT AND METHOD - The present invention relates to a method of forming a bone composite, comprising: providing bone tissue; grinding said bone tissue to form ground tissue; molding the ground bone tissue into a bone composite; applying a binder to the bone composite; applying a vacuum to the mold, and optionally milling or refining the bone composite to the desired shape. The present invention includes the use of a carbohydrate, water, cyanoacrylate and demineralized bone. | 09-27-2012 |
| 20120253470 | COMPOSITIONS FOR BONE TISSUE REPAIR AND USES THEREOF - The technology described herein relates to compositions for promoting bone growth or regeneration. The compositions described herein can comprise bioactive agents and scaffold materials. | 10-04-2012 |
| 20120259425 | Precision Shaped Compressed Demineralized Cancellous Bone Product and Method to Make Same - The precision formed compressed demineralized cancellous bone matrix product is made by the process of: (a) providing a demineralized cancellous bone matrix in a compression mold for the tissue implant; (b) freeze-drying the demineralized cancellous bone matrix in the mold to form freeze-dried compressed demineralized cancellous bone matrix; (c) compressing the matrix contained within the compression mold for a time and under conditions sufficient to form a tissue implant part there from; and (d) removing the precision formed compressed demineralized cancellous bone matrix product. In an alternative embodiment, the precision formed compressed demineralized cancellous bone matrix product is made by: (a) providing a compressed demineralized cancellous bone matrix; (b) freeze-drying the compressed demineralized cancellous bone matrix to form freeze-dried compressed demineralized cancellous bone matrix; and (c) cutting said compressed demineralized cancellous bone matrix to form tissue implant or tissue implant part. The precision formed compressed demineralized bone matrix product can promote healing. | 10-11-2012 |
| 20120265321 | ARTIFICIAL BONES AND METHODS OF MAKING SAME - An artificial bone generally includes a substantially continuous outer wall defining an inner cavity, an inner core disposed within at least a portion of the inner cavity, wherein the inner core includes a porous material having stiffness within a range of stiffness properties for mammalian cancellous bone and strength within a range of strength properties for mammalian cancellous bone, and a barrier layer disposed between the outer wall and the inner core to separate the outer wall from the porous material. | 10-18-2012 |
| 20130218291 | PLGA/HA HYDROXYAPATITE COMPOSITE BONE GRAFTS AND METHOD OF MAKING - The present invention involves tissue engineering constructs made from a new composite bone graft material made from biocompatible poly(D,L-lactic-co-glycolic acid) (PLGA) and bioceramic particles exposed on its surface using a gas foaming particle leaching (GF/PL) method and infused with collagen. Methods and apparatus for of forming scaffolds are also disclosed. | 08-22-2013 |
| 20130253661 | METHOD AND APPARATUS FOR TREATING BONE FRACTURES, AND/OR FOR FORTIFYING AND/OR AUGMENTING BONE, INCLUDING THE PROVISION AND USE OF COMPOSITE IMPLANTS - A composite implant comprising an injectable matrix material which is flowable and settable, and at least one reinforcing element for integration with the injectable matrix material, the at least one reinforcing element adding sufficient strength to the injectable matrix material such that when the composite implant is disposed in a cavity in a bone, the composite implant supports the bone. | 09-26-2013 |
| 20130261764 | MULTIFUNCTIONAL PROSTHESES WITH MULTILAYER COVERING AND METHODS OF PRODUCTION THEREOF - Multifunctional prostheses which include a prosthesis body having at least one interface wall suitable for interfacing with at least one bone tissue, and which also include a substrate are provided. Advantageously, a first covering comprising first functional groups suitable to form chemical bonds, is applied to said substrate. On the side of the first covering the substrate may include protuberances and/or recesses suitable for promoting the attachment of said first functional groups. A second covering comprising nanostructures may be applied to the first covering, on the side opposite the substrate, and an interface covering comprising molecules may be applied to the second covering on the side opposite the first covering. Second functional groups suitable to form chemical bonds, so as to strengthen the bonds between the second covering and the interface covering may be inserted between the interface covering and the second covering. Methods of making such prostheses are also provided. | 10-03-2013 |
| 20130304229 | BONE REGENERATION USING BIODEGRADABLE POLYMERIC NANOCOMPOSITE MATERIALS AND APPLICATIONS OF THE SAME - A structure of, and a method of producing, a biocompatible structure for bone and tissue regeneration are disclosed. The method includes dissolving a polyurethane polymer in methanol, adding hydroxyapatite (HAP) nanoparticles to form a uniformly distributed mixture, applying the mixture to a polytetrafluoroethylene (PTFE) surface to form a polymer film, cutting the polymer film into strips, stacking the strips with layers of bone particles disposed therebetween, coating the stacked strips and layers by the mixture and allowing it to dry, adding bone particles to the coating, and plasma treating the structure to form the biocompatible structure. A weight percentage of the HAP nanoparticles to the polymer is about 5-50% such that a resorption rate of the biocompatible structure substantially matches a rate of tissue generation in the biocompatible structure. | 11-14-2013 |
| 20130325142 | ANISOTROPIC POROUS SCAFFOLDS - A method of fabricating an anisotropic porous scaffold includes heating a previously-formed porous metal scaffold to permit deformation of a material of the previously-formed porous metal scaffold, and deforming, while heated, the previously-formed porous metal scaffold in at least a first direction. | 12-05-2013 |
| 20130345825 | BONE SUBSTITUTE MATERIAL - The invention relates to: —a porous biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material comprising a sintered CAP core and at least one uniform and closed epitactically grown layer of nanocrystalline HAP deposited on top of the sintered CAP core, whereby the epitactically grown nanocrystals have the same size and morphology as human bone mineral, i.e. a length of 30 to 46 nm and a width of 14 to 22 nm, which is impregnated with collagen fibers at a weight ratio of said collagen fibers to said porous biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material of at least 2%,—a process of preparing the above porous CAP/HAP bone substitute material, which comprises (a) mixing a slurry of collagen fibers and a porous biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material comprising a sintered CAP core and at least one uniform and closed epitactically grown layer of nanocrystalline HAP deposited on top of the sintered CAP core, whereby the epitactically grown nanocrystals have the same size and morphology as human bone mineral, i.e. a length of 30 to 46 nm and a width of 14 to 22 nm, and (b) eliminating the water by vacuum suction, —an implant which comprises a porous collagen matrix surrounding and impregnating particles or granules of porous biphasic calcium phosphate/hydroxyapatite (CAP/HAP) bone substitute material comprising a sintered CAP core and at least one uniform and closed epitactically grown layer of nanocrystalline HAP deposited on top of the sintered CAP core, whereby the epitactically grown nanocrystals have the same size and morphology as human bone mineral, i.e. a length of 30 to 46 nm and a width of 14 to 22 nm, —the use of the above bone substitute material as implant or pros thesis for bone formation, bone regeneration, bone repair and/or bone replacement at a defect site in a human or animal. | 12-26-2013 |
| 20140005796 | CERAMIC MONOBLOCK IMPLANTS WITH OSSEOINTEGRATION FIXATION SURFACES | 01-02-2014 |
| 20140012393 | COMPLEX SUPPORT BODY FOR REGENERATING BONE-CARTILAGE, METHOD FOR MANUFACTURING THEREOF, AND COMPOSITION FOR TREATING BONE AND CARTILAGE RELATED DISEASES COMPRISING SAME AS ACTIVE INGREDIENT - The present invention relates to a complex support body for regenerating bone-cartilage, a method for manufacturing thereof, and a composition for treating bone and cartilage related diseases comprising the same as an active ingredient, and more particularly, to a complex support body for regenerating bone-cartilage, which comprises a bone regeneration layer consisting of a biodegradable polymer and a biocompatible ceramic, and a cartilage regeneration layer, which is coupled to the bone regeneration layer and in which cells that can be differentiated into cartilages cells are fixed; a method for manufacturing thereof; and a composition for treating bone and cartilage related diseases comprising the same as an active ingredient. The complex support body of the present invention for regenerating bone-cartilage is manufactured as a three-dimensional support body, which is similar to a living tissue, according to a bioplotting method, and exerts the effect of regeneration into a bone tissue and a cartilage tissue, respectively, depending on materials encountered in the environment where the complex support body for regenerating bone-cartilage is used. | 01-09-2014 |
| 20140121781 | INJECTABLE AND MOLDABLE BONE SUBSTITUTE MATERIALS - An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites. | 05-01-2014 |
| 20140222159 | ASSEMBLED CARTILAGE REPAIR GRAFT - Bifunctional and assembled implants are provided for osteochondral implantation. | 08-07-2014 |
| 20140243993 | CARTILAGE MOSAIC COMPOSITIONS AND METHODS - Compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles and a biocompatible carrier are provided. Methods of manufacturing cartilage compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles are also provided. | 08-28-2014 |
| 20140257513 | COMPOSITE DEVICE THAT COMBINES POROUS METAL AND BONE STIMULI - An orthopaedic implant for filling voids in bones, and methods of using the same. The orthopaedic implant comprises an open porous metal component, having pores for promoting bone regeneration, and a resorbable bone growth promoting component which is resorbed into new bone. The orthopaedic implant and methods of the present disclosure provide structural support for the bone as well as osteoconductive and/or osteoinductive matrix for promoting bone re-growth within bone void. Advantageously, the orthopaedic implants and methods disclosed herein are useful in filling critically sized bone voids. | 09-11-2014 |
| 20140277569 | HYBRID OSTEOINDUCTIVE BONE GRAFT - A bone implant includes a first surface and a second surface. The first and second surfaces include a bioresorbable material. A third surface includes a biocompatible material disposed between the first and second surfaces. The third surface extends between a first end and a second end. The first and second ends each include an inner surface defining a cavity configured for disposal of a spinous process. The bioresorbable material of the first and second surfaces is a faster resorbing material than the biocompatible material of the third surface. The third surface provides structural integrity of the implant to maintain distraction between spinous processes so that the first and second surfaces fuse with at least a portion of the spine. | 09-18-2014 |
| 20140277570 | BONE GROWTH PROMOTION SYSTEMS AND METHODS - This disclosure describes systems and methods for providing a novel delivery system for implantation in a patient. Further, this disclosure describes a delivery system including a carrier that is made of at least one monolithic bone tissue for retaining one or more substances. | 09-18-2014 |
| 20140296996 | MEMBRANE-TYPE ARTIFICIAL SCAFFOLD AND METHOD FOR FABRICATING SAME - Provided herein are a membrane-type artificial scaffold for guided bone regeneration (GBR) and a method for fabricating the same. The membrane-type artificial scaffold according to the present invention comprises: a first layer made of at least one fiber layer arranged in parallel with each other with a first spacing therebetween such that the fiber layer contacts a bone tissue in vivo; and a second layer stacked on the first layer and made of at least one fiber layer arranged parallel to each other with a second spacing therebetween such that the fiber layer contacts a soft tissue in vivo. The first spacing is larger than the second spacing. | 10-02-2014 |
| 20140303744 | DEVICES AND METHODS FOR TREATING DEFECTS IN THE TISSUE OF A LIVING BEING - An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may include, or have blended in, an additive, such as an osteoinductive factor, for example biocompatible ceramics and glass. | 10-09-2014 |
| 20140324187 | Implants and Methods for Correcting Tissue Defects - An implant comprises a plurality of discrete biocompatible molded cement mosaic plates of maximum width w and thickness d connected by wire arms molded into and extending substantially laterally from the mosaic plates. Neighbouring mosaic plates are separated by a gap of width t, and at least some of the mosaic plates have a hexagon shape. | 10-30-2014 |
| 20140358247 | METHODS AND APPARATUS FOR A MULTIPLE TRANSITION TEMPERATURE IMPLANT - A shape-memory device manufactured from shape memory material includes multiple activation temperatures. The multiple activation temperatures arise from either the heat treatment of the device during manufacturing, or by combining different elements with different activation temperatures. To manufacture a shape-memory device with multiple activation temperatures, it is formed into a first shape. A first portion of the shape-memory device is heated to a first temperature, and a second portion of the shape-memory device is heated to a second temperature. The shape-memory device is then worked into a second shape. Accordingly, the first portion has a first transition temperature, and the second portion has a second transition temperature. In use, the shape-memory device is placed into a desired position. Energy is applied such that the first portion, second portion, or both portions are transformed. | 12-04-2014 |
| 20150032221 | BONE REPAIR MATERIAL - Sliceable bone repair material is a porous block-shaped scaffold containing a hydrogel, wherein the hydrogel is formed by Michael type addition of at least two precursor molecules. Said scaffold is made of a synthetic ceramic material and has interconnected macropores having a diameter above 100 μm. In addition said scaffold has a total porosity of 80 to 95%. The total volume of the hydrogel is smaller than the total volume of the interconnected macropores. | 01-29-2015 |
| 20150039097 | BONE REGENERATION USING BIODEGRADABLE POLYMERIC NANOCOMPOSITE MATERIALS AND APPLICATIONS OF THE SAME - A biocompatible structure includes one or more base structures for regeneration of different tissues. Each base structure includes alternately stacked polymer layers and spacer layers. The polymer layer includes a polymer and tissue forming nanoparticles. The polymer includes polyurethane. The tissue forming nanoparticles includes hydroxypatites (HAP) nanoparticles, polymeric nanoparticles, or nanofibers. The spacer layer includes bone particles, polymeric nanoparticles, or nanofibers. The weight percentage of tissue forming nanoparticles to the polymer in the polymer layer in one base structure is different from that in the other base structures. A method of producing the biocompatible structure includes forming multiple base structures stacked together, coating the stacked multiple base structures, and plasma treating the coated structure. | 02-05-2015 |
| 20150081033 | SCAFFOLD-FREE SELF-ORGANIZING 3D SYNTHETIC TISSUE AND ARTIFICIAL BONE COMPLEX FOR BONE/CARTILAGE REGENERATION - An improved method of treating an osteochondral defect is provided, which is a composite tissue for treating or preventing a disease, disorder, or condition associated with an osteochondral defect, comprising a three-dimensional synthetic tissue and an artificial bone, wherein the three-dimensional synthetic tissue is substantially made of a cell and an extracellular matrix derived from the cell, the extracellular matrix contains fibronectin, collagen I, collagen III, and vitronectin, and the extracellular matrix is diffusedly distributed in the tissue. | 03-19-2015 |
| 20150142126 | SYSTEM AND METHOD FOR ATTACHING SOFT TISSUE TO AN IMPLANT - One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein the porous region exhibits a nano-textured surface, and a biocompatible polymer matrix coating the nano-textured surface. The polymer matrix coating comprises a naturally occurring extracellular matrix with biocompatible inorganic materials distributed within the matrix, or a biocompatible polymer and an osteo-inductive agent. | 05-21-2015 |
| 20150328003 | COMPOSITE BONE CONSTRUCTS AND METHODS - Embodiments of the present technology include a graft for administration at a treatment site of a patient. The graft may include a human cadaveric bone material bonded together with a polymeric binder. The human cadaveric bone material may include demineralized bone particles. The demineralized bone particles may have an average diameter less than 1.1 mm, less than 750 μm, less than 500 μm, or less than 250 μm. The human cadaveric bone material may include non-demineralized bone, cancellous bone, and/or cortical bone in embodiments. In some embodiments, bone from animals other than humans may be used, and the patient may be an animal other than a human. | 11-19-2015 |
| 20160038290 | Cartilage Mosaic Compositions and Methods - Compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles and a biocompatible carrier are provided. Methods of manufacturing cartilage compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles are also provided. | 02-11-2016 |
| 20160067046 | COMPOSITE MATERIAL BONE IMPLANT - Radiolucent composite implants. Some embodiments include reconfiguration indicators. Some embodiments include radio-opaque markers, especially along contours. Some embodiments are provided in kit form with accessories such as radiolucent drill guides and/or drives. Some embodiments have fiber reinforcement adapted for various usage scenarios. Some embodiments include metal components, for example, to increase strength. Also described are manufacturing methods. | 03-10-2016 |
| 20160106540 | COMPONENT CONSISTING OF CERAMICS, COMPRISING PORE CHANNELS - A ceramic component that consists of a shell, a filler material and pore channels that pass through the filler material, and can be used as an implant, particularly as a spacer. | 04-21-2016 |
| 20160106838 | METHOD AND APPARATUS FOR TREATING BONE FRACTURES, AND/OR FOR FORTIFYING AND/OR AUGMENTING BONE, INCLUDING THE PROVISION AND USE OF COMPOSITE IMPLANTS - A composite implant comprising an injectable matrix material which is flowable and settable, and at least one reinforcing element for integration with the injectable matrix material, the at least one reinforcing element adding sufficient strength to the injectable matrix material such that when the composite implant is disposed in a cavity in a bone, the composite implant supports the bone. A method for treating a bone comprising: selecting at least one reinforcing element to be combined with an injectable matrix material to form a composite implant capable of supporting the bone; positioning the at least one reinforcing element in a cavity in the bone; flowing the injectable matrix material into the cavity wherein the injectable matrix material interfaces with the at least one reinforcing element; and transforming the injectable matrix material from a flowable state to a nonflowable state to establish a static structure that supports the adjacent bone. | 04-21-2016 |
| 20160114077 | ELASTOMERIC AND DEGRADABLE POLYMER SCAFFOLDS AND HIGH-MINERAL CONTENT POLYMER COMPOSITES, AND IN VIVO APPLICATIONS THEREOF - This invention provides novel synthetic bone grafting materials or tissue engineering scaffolds with desired structural and biological properties (e.g., well-controlled macroporosities, spatially defined biological microenvironment, good handling characteristics, self-anchoring capabilities and shape memory properties) and methods of their applications in vivo. | 04-28-2016 |
| 20160166385 | OSTEOGRAFT IMPLANT | 06-16-2016 |
| 20160250025 | INJECTABLE AND MOLDABLE BONE SUBSTITUTE MATERIALS | 09-01-2016 |
