Class / Patent application number | Description | Number of patent applications / Date published |
607050000 | Promoting tissue growth or healing | 75 |
20080255633 | METHODS AND SYSTEMS FOR FOCUSED BIPOLAR TISSUE ABLATION - Large tissue regions are treated using pairs of electrode arrays. The electrode arrays may be concave and disposed in tissue so that their concave portions are opposed to each other. Axial conductors may be provided extending from the arrays and toward each other in order to increase the heating of tissues lying along the axis between the deployed electrode arrays. By properly spacing the electrode arrays apart and selecting the diameters of the arrays, desired volumes of tissue may be treated, typically with a bipolar, radiofrequency current. | 10-16-2008 |
20080269838 | REGULATION OF GENES VIA APPLICATION OF SPECIFIC AND SELECTIVE ELECTRICAL AND ELECTROMAGNETIC SIGNALS - Methods and devices for the regulation of gene expression by cells via the application of fields generated by specific and selective electric and electromagnetic signals so as to target diseased or injured tissue for treatment. By gene expression is meant the up regulation or down regulation of the process whereby specific portions (genes) of the human genome (DNA) are transcribed into mRNA and subsequently translated into protein. Methods and devices are provided for the targeted treatment of injured or diseased tissue that include providing specific and selective electric and electromagnetic signals and exposing tissue to the fields generated by the signals so as to regulate gene expression. In particular, methods and devices are provided for the targeted treatment of bone defects, osteoarthritis, osteoporosis, cancer, and other disease states. | 10-30-2008 |
20080294222 | APPARATUS FOR ATTACHMENT AND REINFORCEMENT OF TISSUE, APPARATUS FOR REINFORCEMENT OF TISSUE, METHODS OF ATTACHING AND REINFORCING TISSUE, AND METHODS OF REINFORCING TISSUE - There are disclosed methods and apparatus for attachment and reinforcement of tissue, and methods and apparatus for reinforcement of tissue. In an embodiment, the apparatus includes an energy applicator configured to apply energy to generate heat within a target tissue to evaporate water to create dried tissue, and denature at least one of collagen and elastin to attach portions together, and a biopolymer applicator configured for to receive the heat generated to allow biopolymer material to change from solid to molten, and to allow the biopolymer to fill dried tissue to reinforce portions of the target tissue and provide a hermetic seal. | 11-27-2008 |
20080306571 | Devices For Treatment of Central Nervous System Injuries - A device for stimulating axon growth of the nerve cells in the spinal cord of mammals includes a device having a DC stimulus generator ( | 12-11-2008 |
20080319507 | Tissue Treatment Device and Method of Restricting Use of Device - Embodiments include electromagnetic energy-based tissue treatment devices which comprise biometric sensors in combination with memory storing biometric data from authorized treatment providers, and methods of restricting use of the devices based on comparing biometric data from potential treatment providers to the stored biometric data from authorized treatment providers. Delivery of a treatment can be permitted when the biometric data from a potential treatment provider is found to match the biometric treatment data for an authorized treatment provider. The devices of the invention can further be configured to collect usage data and usage setting of the device, and usage data can be used in conjunction with biometric data to determine whether or not an authorized user has exceeded or will exceed a recommended treatment regimen. | 12-25-2008 |
20090018613 | REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) GENE EXPRESSION IN TISSUE VIA THE APPLICATION OF ELECTRIC AND/OR ELECTROMAGNETIC FIELDS - Methods and devices for the regulation of gene expression in tissue by applying an electric and/or electromagnetic field generated by specific and selective signals so as to treat diseases, conditions, and/or tissue. Gene expression is the up-regulation or down-regulation of the process whereby specific portions (genes) of the human genome (DNA) are transcribed into mRNA and subsequently translated into protein. Methods and devices are described for the regulation of Vascular Endothelial Growth Factor (VEGF) protein gene expression in endothelial cells of various targeted tissues via the capacitive coupling or inductive coupling (e.g., by electrodes or one or more coils or other field generating devices disposed with respect to the targeted cells) of specific and selective signals to the cells of these tissues, where the resultant electric and/or electromagnetic fields treat diseased or injured tissues. The resulting methods and devices are useful for the targeted treatment of peripheral vascular disease, cardiovascular disease, macular degeneration, wound healing, tendon and ligament healing, in preventing tumor growth or spread, and other conditions in which VEGF protein may be implicated. | 01-15-2009 |
20090062885 | Method and device for treating osteoarthritis and cartilage disease, defects, and injuries in the human hip - A method of determining the voltage and current required for the application of specific and selective electric and electromagnetic signals to diseased articular cartilage in the treatment of osteoarthritis, cartilage defects due to trauma or sports injury, or used as an adjunct with other therapies (cell transplantation, tissue-engineered scaffold, growth factors, etc.) for treating cartilage defects in the human hip joint and a device for delivering such signals to a patient's hip. Anatomic, analytical, and planar circuit models are developed to determining the impedances, conductivities, and current flows in the human hip joint and its surrounding soft tissues and skin that are required to produce a 20 mV/cm electric field in the synovium and articular cartilage of the human hip. The voltage of the signal applied to the surface electrodes or to a coil(s) or solenoid is varied based on the size of the hip joint; larger hip joints require larger voltages to generate the effective electric field. | 03-05-2009 |
20090112286 | NEURAL CHANNEL BRIDGE AIDED BY A MICRO-ELECTRONIC SYSTEM - Methods and equipment used to regenerate sensory, motorial, or visceral signals of injured, broken or diseased nerves of mammalia, such as humans, are provided. In some embodiments, a lineup of downward and upward channels to bridge injured neural channels is disclosed. The downward or upward channels can be connected to electrodes which are in contact with upper or lower nerve stumps. The channels can be used to detect, amplify, and recognize the motorial or sensory signals, to generate related Functional Electrical Stimulation (FES) signals, and to supply the FES signals to the electrodes on the lower or upper nerve stumps. Neural signals can thus be regenerated and the injured motorial or sensory channels can be bridged. | 04-30-2009 |
20090132003 | Wireless Electrical Stimulation of Neural Injury - An apparatus for wireless electrical stimulation of a neural injury includes a first electronic implant ( | 05-21-2009 |
20090240306 | Pancreatic stimulator for type II diabetes - The present invention relates to methods of preventing, managing and/or treating blood sugar disorders, particularly those related to diabetes, by stimulating pancreas externally and non-invasively. Therapeutically repairing and regenerating beta cells of islets of langerhans enhance their ability to produce insulin to treat high blood sugar. The transformation of insensitive or impaired islets of langerhans results in an increased insulin secretion and in increased insulin level in blood plasma. This improves the glucose toxicity and improves beta cells dysfunction. This also regulates the pancreatic secretion that induces a feeling of satiety, which leads to weight loss. | 09-24-2009 |
20090254148 | Telemetrically Controllable System for Treatment of Nervous Sytem Injury - An apparatus ( | 10-08-2009 |
20090270945 | Portable Applicator for Collagen Stimulation - A portable applicator for pulsating signal therapy comprises a support body ( | 10-29-2009 |
20100069995 | Method for Improving Functional Recovery After Stroke by Electrical Stimulation of a Cranial Nerve - According to some embodiments, a method for improving functional recovery after cerebro-vascular accidents, such as strokes, in humans and animals comprises stimulating a cranial nerve with electrical current. According to some embodiments, a method for improving functional recovery after stroke in a human or animal in need thereof comprises applying to the cranial nerve of the human or animal a stimulating electrical signal that causes neurophysiological, morphological, chemical, or neuronal connective alteration in the brain, where the alteration changes neural function in the brain so as to change functional recovery and functional dynamics in the human or animal. According to some embodiments, a method for improving functional recovery after stroke in a human or animal in need thereof comprises applying to a first cranial nerve a first stimulating electrical signal optimized so as to promote stroke recovery. The method may further comprise applying to one or more of the first cranial nerve and a second cranial nerve a second stimulating electrical signal optimized so as to control a concomitant dysfunction. | 03-18-2010 |
20100087894 | HIGH-FREQUENCY TREATMENT APPARATUS AND HIGH-FREQUENCY TREATMENT METHOD - A high-frequency treatment apparatus includes a treatment high-frequency wave output unit configured to output a treatment high-frequency wave to be applied to a treatment target living tissue, a detection unit for detecting an impedance of the treatment target living tissue, and a control unit configured to control the treatment high-frequency wave output unit on the basis of the result of the detection in the detection unit, the control unit configured to set a treatment frequency of the treatment high-frequency wave to a first treatment frequency in order to treat the living tissue primarily by Joule heat when the impedance of the treatment target living tissue is lower than a threshold value and to set the treatment frequency to a second treatment frequency higher than the first treatment frequency in order to treat the living tissue primarily by high-frequency dielectric heating when the impedance of the treatment target living tissue is higher than the threshold value. | 04-08-2010 |
20100094380 | ELECTRONEURAL INTERFACE FOR A MEDICAL IMPLANT - Embodiments are generally directed to improving the interface between one or more electrode contacts of a medical implant and the neurons of a recipient of the medical implant. In an embodiment, a growth factor is applied to stimulate the growth of peripheral processes (also referred to as dendrites). Then an electric field is applied to direct the growth of the peripheral processes towards the electrode contact. Growing peripheral processes towards the electrode contacts may reduce the charge required to stimulate the peripheral processes and improve operation of the medical implant. | 04-15-2010 |
20100131031 | METHODS OF DIAGNOSIS AND TREATMENT OF WOUNDS, METHODS OF SCREENING FOR ELECTRICAL MARKERS FOR WOUNDS PROGNOSIS IN PATIENTS - Described herein are electrical markers, specifically alternate current (AC) signals whose appearance in patients with wounds, specifically chronic wounds, correlates to the prognosis of the wounds. Related methods that can be used for diagnosis and treatment of wounds are disclosed. Also described herein are methods that can be used to identify electrical signals of wounds. | 05-27-2010 |
20100152811 | NERVE REGENERATION SYSTEM AND LEAD DEVICES ASSOCIATED THEREWITH - Various systems and methods for promoting nerve regeneration are disclosed. The system may include an elongated lead configured to be implanted within a patient's body. The system may also include a plurality of electrodes disposed along the elongated lead and configured to deliver electric stimulation to an area of a patient's body. The plurality of electrodes may comprise at least one transmitting electrode in communication with the controller, wherein the at least one transmitting electrode is configured to transmit an electric signal to one or more other electrodes. The controller may be configured to control operation of the at least one transmitting electrode. | 06-17-2010 |
20100152812 | SYSTEMS AND METHODS FOR PROMOTING NERVE RECOGNITION - Various exemplary systems and methods for promoting nerve regeneration are disclosed. In certain exemplary embodiments, a nerve regeneration system may include a lead configured to be placed in a body proximate a damaged nerve, a portion of the lead being configured to stimulate the damaged nerve. The system may also include a control module configured to monitor a signal indicative of the nerve's response to the stimulation and adjust a parameter of the stimulation in response to the monitored signal. | 06-17-2010 |
20100160999 | Electrical Stimulation of Cell and Tissue Growth with Two-and Three-Dimensionally Patterned Electrodes - The present invention is generally directed to a method for regulating cellular and tissue physiology, a device for practicing the method, and a process for fabricating the device. In general the process comprises the steps of providing at least one patterned electrode, providing a least one cell, placing the at least one electrode in electrical communication with the at least one cell, and applying a voltage to the electrode thereby delivering an effective amount of a patterned electric field or current thus regulating the physiology and/or growth of the at least one cell. | 06-24-2010 |
20100174343 | APPARATUS AND METHODS FOR FACILITATING WOUND HEALING AND TREATING SKIN - Electrode systems and methods are provided for applying electrical stimulation to a wound or skin. The electrode systems may include a feedback sensor configured to detect at least one wound healing factor or other treatment factors and may adjust the electrical stimulation based on feedback sensor measurements. The electrode systems may include multiple center electrodes for attachment to the wound. Multiple therapies may be stored on the electrode systems and a selected one of the stored therapies may be applied. A timer may be included to indicate the length of time a therapy has been applied. The electrode system may include a control module configured as a flexible circuit which conforms to the shape of the wound or the skin to which it is applied. In addition, a medical kit may be supplied for use in applying therapies, including multiple control modules and multiple electrodes. | 07-08-2010 |
20100204752 | Negative Pressure and Electrostimulation Therapy Apparatus - A negative wound pressure therapy apparatus includes a wound dressing for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around wound tissue. The apparatus also includes a fluid conduit in fluid communication with the reservoir. The fluid conduit defines a fluid flow path for carrying fluids from the reservoir. The apparatus also includes a vacuum source in fluid communication with the fluid conduit. The vacuum source is suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. The apparatus also includes at least one biomedical electrode mounted with respect to the wound dressing for transmitting electrical energy to stimulate healing of the wound tissue. | 08-12-2010 |
20100204753 | CELL CONSTRUCT, ITS PROCESS OF MANUFACTURE, AS WELL AS A DEVICE, IMPLANT AND PROCESSES FOR THE MECHANICAL STIMULATION OF CELLS IN VITRO AND IN VIVO - A cell construct includes cells in contact with at least one basement membrane and/or at least one stroma, wherein the basement membrane or stroma contains elements for applying mechanical stimulation on the cells. The process of manufacture of the cell construct and its use, as well as a device, an implant and processes for the mechanical stimulation of cells in vitro and in vivo are also described. | 08-12-2010 |
20100268300 | LOW FREQUENCY ELECTRICAL STIMULATOR DEVICE FOR THE PREVENTION AND TREATMENT OF CHRONIC WOUNDS - A low frequency electrical stimulation device for the prevention and healing of chronic wounds resulting from diabetes, or other type of pathology. This device applies electrical stimulation through a square bipolar signal, and a paused squared bipolar signal in at least one of the output channels, and at different therapy times and frequencies that will depend upon the specific needs of the patient. | 10-21-2010 |
20100280573 | METHOD FOR ELECTRICAL STIMULATION OF CUTANEOUS SENSORY RECEPTORS - A method of stimulating sensory nerves is disclosed that comprises the steps of providing an electrode plate with a pattern of needle-like (NL) electrodes and conductive plate (CP) electrodes disposed on a front face of the plate element, the NL electrodes being configured to apply electrical stimulation to cutaneous Aδ/C fibers, and the CP electrodes being configured to apply electrical stimulation to cutaneous Aβ fibers; mounting the electrode plate on a patient's skin with the front face in an abutting relationship with the patient's skin, the abutting relationship causing the NL electrodes to penetrate the epidermis of the patient's skin; and applying electrical stimulation to the patient's skin via the pattern of NL electrodes and CP electrodes, the electrical stimulation being applied so that Aβ fiber input from the CP electrodes overlaps in time at the patient's spinal cord and/or brain stem with Aδ/C fiber input from the NL electrodes. | 11-04-2010 |
20100292756 | BIOELECTRIC IMPLANT AND METHOD - Bioelectric implants are provided in three distinct embodiments, namely a bone/tissue anchor, a suture construction, and a plate. The bioelectric implants function in dual capacities as both fixation devices, and as galvanic cells for the production of electrical energy used for therapeutic purposes in tissue regeneration and healing. The bioelectric anchor may take the general form of a screw or pin having a hollow interior or cavity that extends through the body of the anchor. A coating can be applied to the cavity to form the anode portion of the galvanic cell. The outer surface of the anchor serves as a cathode. Bodily fluids and tissue act as an electrolyte to facilitate the chemical reactions necessary for the galvanic cell. For the suture construction, one or more strands of material are the cathode, and one or more strands of peripheral surrounding material act as the anode. Bodily fluids/tissue in contact with the suture act as an electrolyte. The bioelectric plate can be used in combination with the bioelectric anchor to supplement delivery of electrical energy. The plate has anode and cathode portions also making it a source of electrical energy. | 11-18-2010 |
20100292757 | METHOD AND DEVICE FOR PLASMA-SUPPORTED SURFACE TREATMENT - A method and a series of devices for dry cleaning, activating, modifying, coating, and biologically decontaminating (degerming, disinfecting, sterilizing) surfaces by means of an atmospheric pressure plasma generated using a surface barrier discharge are provided. The invention is used for dry cleaning, activating, coating, modifying, and biologically contaminating surfaces by means of an atmospheric pressure plasma generated in a defined, flowing gas atmosphere by a surface barrier discharge, comprising a high-voltage electrode that is covered with a dielectric or ferroelectric material, an electrically conducting grounded contact electrode, a high-voltage supply, a gas supply, and a gas nozzle (encompassing a gas outlet); said gas nozzle is located in the direct vicinity of the grounded contact electrode, is integrated into the contact electrode, or acts as the grounded contact electrode. | 11-18-2010 |
20100331910 | ELECTRICAL STIMULATION UNIT AND WATERBATH SYSTEM - A method and apparatus for treating an appendage of a subject. The apparatus provides for exposing the appendage to an aqueous solution; and providing a pulsed current to the aqueous solution to treat the appendage. | 12-30-2010 |
20110015697 | ELECTRICAL WOUND HEALING SYSTEM AND METHOD - A wound healing system comprising an array of electrodes incorporated in a device for applying an electrical signal to a wound. The electrodes are configurable to form at least one composite electrode and the electrical signal is applied to the wound via the composite electrode(s). The system preferably includes means for determining the state of the wound, the electrode composition of the composite electrode(s) depending on the determined state of the wound. Advantageously, the electrode composition of the composite electrode(s) is adjustable in response to changes in the determined state of the wound. | 01-20-2011 |
20110015698 | PULSED ELECTROMAGNETIC ENERGY TREATMENT APPARATUS AND METHOD - An apparatus and method for the treatment of chronic wounds using electromagnetic energy. The apparatus includes a generator and at least one applicator. The generator can produce electromagnetic energy and the applicator can apply the electromagnetic energy produced by the generator. A detector is disposed on the applicator that can measure the field strength of the electromagnetic energy applied. | 01-20-2011 |
20110093037 | COMPLIANT ELECTRODE FOR PATENT FORAMEN OVALE CLOSURE DEVICE - A medical device for use in delivering RF energy to a tissue opening is disclosed. In one embodiment, the medical device comprises a compliant electrode. The compliant electrode can include a shape memory material, such as NITINOL, to facilitate the electrode having at least one relaxed orientation. The electrode can be deployed from a delivery shaft inside the left atrium, for example, of a heart through the delivery shaft. The electrode can be configured to substantially conform to the tissue proximate the tissue opening. After energy is applied to the tissue between the left and right electrodes, the left electrode can be removed from the left atrium by being received back into the delivery shaft and the delivery shaft thereafter removed from the opening. | 04-21-2011 |
20110112606 | Semiconductor System Integrated With Through Silicon Vias for Nerve Regeneration - An integrated circuit (IC) chip ( | 05-12-2011 |
20110144718 | COMPOSITION AND METHOD FOR THE TREATMENT OR PREVENTION OF SPINAL DISORDERS - The present invention provides compositions of matter suitable for the prevention of and/or treatment of a spinal disorder and/or spinal pain, e.g., caused by and/or associated with intervertebral disc (IVD) degeneration and methods of treatment of a spinal disorder and/or spinal pain. For example, the compositions of the present invention comprise a modulator of growth differentiation factor (GDF)-6 signaling sufficient to reduce or prevent or delay IVD degeneration and/or to enhance or induce IVD regeneration. The present invention also provides medical devices comprising said compositions, and methods of treatment making use of said compositions. | 06-16-2011 |
20110178574 | WOUND TREATMENT SYSTEM AND METHOD - A wound treatment system and method is described. The system includes a silver containment element and an electromagnetic element. The electromagnet element is controllable to produce a pulsed magnetic field proximate to the silver containment element to control the number of active ions in the silver containment element. | 07-21-2011 |
20110190849 | NEURAL STIMULATION DEVICES AND SYSTEMS FOR TREATMENT OF CHRONIC INFLAMMATION - A system for treating chronic inflammation may include an implantable microstimulator, a wearable charger, and optionally an external controller. The implantable microstimulator may be implemented as a leadless neurostimulator implantable in communication with a cervical region of a vagus nerve. The microstimulator can address several types of stimulation including regular dose delivery. The wearable charger may be worn around the subject's neck to rapidly (<10 minutes per week) charge an implanted microstimulator. The external controller may be configured as a prescription pad that controls the dosing and activity of the microstimulator. | 08-04-2011 |
20120004703 | Electrosurgical Generator to Ablation Device Adaptor - An electrosurgical system is provided that includes an electrosurgical generator configured to output a first electrosurgical waveform and a probe configured to deliver a second electrosurgical waveform to tissue. The system also includes an adapter coupled between the electrosurgical generator and the probe and operable to convert the first electrosurgical waveform to the second electrosurgical waveform. The adapter includes a step down transformer configured to convert the first electrosurgical waveform to the second electrosurgical waveform. | 01-05-2012 |
20120016441 | DEVICE FOR ELECTRIC PULSE STIMULATION OF HEALING OF WOUNDS - A device that improves the efficiency of the treatment process, shortens healing time, and treats large-area wound surfaces and various forms of local inflammatory processes comprising an HF generator, power source, timer, pedal, electronic module control device, and a device for delivering exposure energy from the generator to biological tissue, wherein the pedal is pressed, a signal arrives at a timer and electronic module for controlling a device for the metered movement of a needle electrode. By means of this module, movement to a specified depth can be ensured. After the needle electrode is inserted into biological tissue, a signal to turn on the HF generator is sent automatically from the timer and a movement sensor. The current of the HF generator is modulated by a modulator that is fed to needle electrode. The timer turns off the HF generator, and the needle electrode is extracted from the biological tissue. | 01-19-2012 |
20120035683 | METHOD FOR TREATING DEGENERATIVE DISC DISEASE USING NONINVASIVE CAPACITIVELY COUPLED ELECTRICAL STIMULATION DEVICE - A method for treatment of degenerative disc disease using capacitively coupled electrical stimulation. In one embodiment, a subject diagnosed as having degenerative disc disease is treated by placing first and second electrodes on the subject's body at the site of an identified disc in a state of degenerative disc disease, and applying an electric field to the identified disc via the first and second electrodes with the intent to treat the degenerative disc disease. The electric field is created with an electrical signal having a frequency within a range of 20 to 100 kHz and having a symmetrical waveform with an amplitude within a range of 0.1 to 20 volts peak-to-peak, preferably a frequency of approximately 60 kHz and an amplitude of approximately 5 volts peak-to-peak. | 02-09-2012 |
20120065703 | Conductive Biopolymer Implant For Enhancing Tissue Repair And Regeneration Using Electromagnetic Fields - Embodiments of the present invention relate generally to the field of tissue repair and regeneration. More specifically, embodiments of the present invention relate to medical devices, materials or constructs, such as conductive biocompatible polymers having one or more networks of metal nanowires that enhance tissue repair and regeneration using electromagnetic fields. | 03-15-2012 |
20120089201 | METHOD AND APPARATUS FOR ELECTROMAGNETIC ENHANCEMENT OF BIOCHEMICAL SIGNALING PATHWAYS FOR THERAPEUTICS AND PROPHYLAXIS IN PLANTS, ANIMALS AND HUMANS - Apparatus and methods for delivering electromagnetic signals configured specifically to accelerate the asymmetrical kinetics of the binding of intracellular ions to their respective intracellular buffers, to enhance the biochemical signaling pathways plant animal and human molecules, cells, tissues, organs, portions of entire organisms and entire organisms employ for growth, repair and maintenance. Described herein are devices and methods that utilize repetitive bursts of waveforms configured to maximize the bound concentration of intracellular ions at their associated molecular buffers to enhance the biochemical signaling pathways living systems employ for growth, repair and maintenance. For example the systems and methods described herein may drive the binding of calcium to calmodulin (CaM), thereby enhancing the CaM-dependent nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling pathway. | 04-12-2012 |
20120136414 | Microcurrent-Generating Topical Or Cosmetic Systems, And Methods Of Making And Using The Same - The present invention relates to a topical or cosmetic system that includes a metal and a semiconductor element. One element acts as an electron donor and the other element acts as an electron acceptor. Such metal and semiconductor elements are in contact through a metal/semiconductor junction. The system also includes an electrically conductive medium that extends across the skin surface and electrically connects the metal and semiconductor elements. The electrical resistance of the conductive medium is significantly smaller than that of the metal/semiconductor junction, so that the majority of electrical current generated between the metal element and the semiconductor element flows across the skin surface through the conductive medium in the absence of any power source. The present invention also relates to methods of using the above-described system for preventing or treating skin damage. | 05-31-2012 |
20120253423 | Artificial Nerve Networking System and Method for Functional Recovery of Damaged Nerve - Disclosed are a system and a method for artificial nerve networking capable of restoring a damaged nerve and allowing selective detection, analysis, transmission and stimulation of a signal from the damaged nerve. The artificial nerve networking system according to an embodiment of the present disclosure includes: a first nerve conduit connected at one end of a damaged nerve; a second nerve conduit connected at the other end of the damaged nerve; and an artificial nerve networking unit electrically connected to the first nerve conduit and the second nerve conduit and recovering the function of the damaged nerve by transmitting and receiving a signal to and from the damaged nerve. | 10-04-2012 |
20120277825 | Apparatus and method for treating and preventing formation of pressure ulcers - An apparatus and means of detecting tissue conditions conducive to pressure ulcer formation and reversing these conditions which includes the steps of: noninvasively detecting tissue parameters indicative of tissue health, calculating when these conditions fall outside normal healthy physiological ranges in such a manner that indicates future formation of a pressure ulcer, and in such a situation applying therapeutic stimulation to normalize tissue physiological condition. Said apparatus and method comprise a single, wearable unit. The device can be used in bed or in a wheelchair to treat and prevent the development of pressure ulcers. | 11-01-2012 |
20130073001 | APPARATUS AND METHOD FOR REJUVENATING SKIN - A skin rejuvenation device and method for the cosmetic or anti-aging reduction of wrinkles and other skin conditions is disclosed. The skin rejuvenation device comprises an array of positive and negative electrodes for the delivery of electrical microcurrents in the attoampere to milliampere range, light sources to deliver photonic stimulation and/or transducers to deliver ultrasonic stimulation to the skin and underlying tissues. | 03-21-2013 |
20130096645 | SURGICAL INSTRUMENTS AND TECHNIQUES FOR TREATING GASTRO-ESOPHAGEAL REFLUX DISEASE - Instruments for thermally-mediated treatment of a patient's lower esophageal sphincter (LES) to induce an injury healing response to thereby populate the extracellular compartment of walls of the LES with collagen matrices to altere the biomechanics of the LES to provide an increased intra-esophageal pressure for preventing acid reflux. A preferred embodiment is a bougie-type device for trans-esophageal introduction that carries conductive electrodes for delivering Rf energy to walls of the LES (i) to induce the injury healing response or (ii) to “model” collagenous tissues of the LES by shrinking collagen fibers therein. | 04-18-2013 |
20130218235 | Excessive fibrous capsule formation and capsular contracture apparatus and method for using same - An apparatus comprising an electromagnetic signal generating means for emitting signals comprising bursts of at least one of sinusoidal, rectangular, chaotic, and random waveforms, having a frequency content in a range of about 0.01 Hz to about 100 MHz at about 1 to about 100,000 waveforms per second, having a burst duration of 1 usec to 100 msec, and having a burst repetition rate from about 0.01 to about 1000 bursts/second, wherein the waveforms are adapted to a frequency response of a fibrous capsule formation and capsular contracture target pathway structure and to have sufficient signal to noise ratio of at least about 0.2 in respect of a given fibrous capsule formation and capsular contracture target pathway structure to modulate at least one of ion and ligand interactions in that fibrous capsule formation and capsular target pathway structure wherein the signal to noise ratio is evaluated by calculating a frequency response of the impedance of the target path structure divided by a calculated frequency response of baseline thermal fluctuations in voltage across the target path structure, an electromagnetic signal coupling means wherein the coupling means comprises at least one of an inductive coupling means and a capacitive coupling means, connected to the electromagnetic signal generating means for delivering the electromagnetic signal to the fibrous capsule formation and capsular contracture target pathway structure, and a garment wherein the electromagnetic signal generating means and electromagnetic signal coupling means are incorporated into the garment. | 08-22-2013 |
20130245716 | SLEEVE FOR STIMULATION OF TISSUE REGENERATION - The regenerative sleeve encompasses the wound site of an amputated appendage and provides an environment conducive to tissue regeneration. The sleeve includes a tubular reservoir having an outer body that encloses the end of the appendage including the wound site and provides a sealed wound space between the wound site and the outer body. The sleeve also includes a cuff disposed in an opening formed in the outer body, the cuff being configured to fit on the appendage, and an access port disposed on the outer body and configured to allow administration of fluids to the wound space. The sleeve assembly was effective in supporting early stages of murine digit tip regeneration when combined with a porcine urinary bladder matrix (UBM) pepsin digest and electrical stimulation. | 09-19-2013 |
20140031897 | DEVICE FOR THE TREATMENT OF SKIN - A skin treatment device includes a roller rotatably mounted about its longitudinal axis and having needles protruding radially outwardly from its peripheral surface, and a device for establishing electrical contact between at least part of the needles and a voltage source having first and second poles, including first and second terminals capable of being electrically connected to the first and second poles, respectively, a first contacting zone electrically connected to first needles, a second contacting zone spaced and electrically insulated from the first contacting zone and electrically connected to second needles, the terminals and the contacting zones being configured such that when the first terminal is connected to the first contacting zone, the second terminal is likewise connected to the second contacting zone. The first and the second needles are each arranged in a row, the rows being separated from each other in a circumferential direction of the roller. | 01-30-2014 |
20140052216 | METHODS FOR PROMOTING WOUND HEALING - A method for promoting wound healing at a wound site includes subjecting the wound site to electrical pulses to promote wound healing during at least one of the stages of wound healing. The method may further include closing the wound site by sutures or staples prior to and or after applying the electrical pulses that promote wound healing. | 02-20-2014 |
20140277273 | SYSTEMS AND METHODS FOR SELECTIVELY MIGRATING CELLS USING ELECTRIC FIELDS - Systems and methods are provided for migrating cells implanted or endogenous in tissue. The system may include first and second delivery electrodes configured for insertion in tissue and a direct current (DC) power source operatively coupled to the first and second delivery electrodes. The system further may include a programmable controller operatively coupled to the DC power source, wherein the programmable controller is programmed to direct the DC power source to deliver an electric field between the first delivery electrode and the second delivery electrode at a stimulation to nonstimulation ratio sufficient to cause the cells to migrate within tissue selectively. | 09-18-2014 |
20150328450 | WOUND TREATMENT - An electrical stimulator system that includes a component configured to deliver an electrical current to a wound, the electrical current being a stochastic alternating current (AC) signal characterized by a frequency spectrum within the range of 0.5-2000 Hz. The system optionally includes electrodes through which the electrical current is delivered. The electrodes are optionally configured to be affixed on two opposing sides of the wound. | 11-19-2015 |
20150374984 | Microcell Data Transmission - An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface. | 12-31-2015 |
20160001073 | APPARATUS AND METHOD FOR STIMULATING HAIR GROWTH AND/OR PREVENTING HAIR LOSS - A method of treating or preventing a hair-condition of a user comprising: subjecting the user's scalp to at least 200 distinct electrode-scalp contact events during a time-interval of at most one minute and dividable into 5 non-overlapping equal-duration sub-intervals covering the time-interval, method performed such that i. for at least a majority of the electrode-scalp contact events, no electrode of the event enters into the dermis; ii. a duration of each electrode contact event is at most 100 milliseconds; and iii. for each electrode contact event, an electrical current flows between the electrode and the scalp so as to deposit electrode-released ions of a first metal or of a second metal on the scalp, thereby forming a respective metal-ion-deposition island on the user's scalp. | 01-07-2016 |
20160015962 | Smart Patch For Wound Management - A flexible patch is provided that is capable of emitting light in the UV, visible, and/or infrared electromagnetic spectrums. The patch contains a feedback process and system using one or more sensors and a controller on the patch to ( | 01-21-2016 |
20160058998 | METHODS AND DEVICES FOR CELLULAR ACTIVATION - An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface. | 03-03-2016 |
20160058999 | Expandable Wound Dressings - A system for wound treatment includes adjunctive wound therapy devices and substrates comprising multiple first reservoirs and multiple second reservoirs. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface. | 03-03-2016 |
20160059008 | SIGNAL ADJUSTMENT FOR ELECTROTHERAPY - Battery-driven stimulators for electrotherapy usually equip with a small battery to generate specified current waveforms applied to human body for stimulation. Such current waveforms can easily get into a saturated status due to high bio-impedance and low battery power. The present disclosure provides a system in which the waveform is adjusted according to feedbacks taken from a patient to reduce or avoid saturation. | 03-03-2016 |
20160059020 | BATTERY PACK FOR ELECTROTHERAPY DEVICES - An electrotherapy device is provided that includes a battery pack which is detachably connected to a stimulation pack that includes a waveform generator and control circuits. The stimulation pack can include a microprocessor, digital and analog circuits such as waveform generator, memory, IO pin, oscillator, and/or ADC and DAC. The battery pack includes a battery holder a charging and protection circuit and a battery indicator. | 03-03-2016 |
20160136417 | TREATING SKIN ULCERS - The invention provides the use of electrical pulses (I, W) to reduce, improve, heal or prevent recurrence of a chronic ulcer, comprising administering to a need ( | 05-19-2016 |
20160158543 | DEVICE FOR TREATING A CUTANEOUS ULCER - A device treats a region of the body of a patient having a cutaneous ulcer, including:
| 06-09-2016 |
607051000 | Hard tissue (e.g., bone) | 16 |
20080215116 | REGULATION OF FIBROBLASTIC GROWTH FACTOR-2 (FGF-2) GENE EXPRESSION IN LIVING CELLS WITH THE APPLICATION OF SPECIFIC AND SELECTIVE ELECTRIC AND ELECTROMAGNETIC FIELDS - Methods and devices are described for the regulation of Fibroblastic Growth Factor-2 mRNA and/or FGF-2 protein in bone cells and other tissues via capacitive coupling or inductive coupling of specific and selective electric and/or electromagnetic fields to the bone cells or other tissues, where the specific and selective fields are generated by application of specific and selective signals to electrodes or one or more coils or other field generating device disposed with respect to the bone cells or other tissues so as to facilitate the treatment of diseased or injured bone and other tissues. By gene expression is meant the up-regulation or down-regulation of the process whereby specific portions (genes) of the human genome (DNA) are transcribed into mRNA and subsequently translated into protein. Methods and devices are provided for the targeted treatment of injured or diseased bone and other tissue that include generating specific and selective signals that generate electric and/or electromagnetic fields in the target tissue optimized for increase of FGF-2 protein gene expression and exposing bone and other tissue to the fields generated by specific and selective signals so as to regulate FGF-2 protein gene expression in such tissue. The resulting methods and devices are useful for the targeted treatment of osteoporosis, osteopenia, osteonecrosis, fresh bone fractures, fractures at risk, nonunion, bone defects, spine fusion, and/or other conditions in which FGF-2 protein has been implicated. | 09-04-2008 |
20090062886 | SYSTEMS AND METHODS FOR DELIVERING ELECTRICAL ENERGY IN THE BODY - Small implantable magnetostrictive-electroactive (ME) device for delivering electrical energy to surrounding tissue. The wireless ME device is activated by a changing magnetic field from an externally applied alternating magnetic field source. The ME device provides a means for stimulating a nerve, tissue or internal organ with direct electrical current, such as relatively low-level direct current for temporary or as needed therapy. The field source (e.g. small coil antenna) may be a hand-held device or affixed to the wearer's skin, clothing or accessories. The ME implant may be configured as pellets which are small enough to be implanted through a surgical needle. In one embodiment, the wireless energy transmission system can be used for stimulating bone growth. | 03-05-2009 |
20090312816 | IONTOPHORETIC AND ELECTROOSMOTIC DISC TREATMENT - Apparatus ( | 12-17-2009 |
20100324626 | Electrotherapy Stimilator for Osteoarthritis - An electrically conductive and compressive wrap is provided having at least a liner of fabric that electronically emits infrared heat therapy to aid electrotherapy into a patient. The conductive wrap emits a low-level pulsed electrical signal associated with the treatment of osteoarthritis and rheumatoid arthritis. The low-level pulse is provided at low amplitude where is it not physically perceived by the user, but at a level that closely mimics the electrical signal that occurs in naturally healing cartilage. The conductive silver fabric serves as an electrode that delivers optimal distribution of current around anatomically adapted, interchangeable and wearable therapy pads for interchangeable use with the therapy system of the present invention. Each pad includes an electrical insulative liner that keeps current applied to the desired area, and a compression cover to simultaneously deliver a therapeutic amount of compressive force to the area. | 12-23-2010 |
20110238132 | Self Powered Ostogenesis and Osseointegration Promotion and Maintenance Device for Endosseous Implant - Osteogenesis and osseointegration promotion and maintenance devices for osseous implants include an implant member having a first electrode, an inlaid second electrode positioned on the member so that it is electrically isolated from and substantially flush with the member surface, and an electrical stimulation mechanism preferably located at the member and operative to provide electrical stimulation signals to endosseous tissue surrounding the implant through the first and second electrodes. The first electrode may be the member itself or a second inlaid electrode. The implant is thus electrically functionalized for osteogenesis and osseointgration acceleration. The device is applicable to both non-dental and dental implants. In all embodiments, the use of inlaid electrode(s) enables the general appearance, external surface and mechanical integrity of the implant to be left essentially unchanged. | 09-29-2011 |
20110288611 | BRACING AND ELECTROSTIMULATION FOR ARTHRITIS - A system for treating arthritis includes at least one joint stabilizing assembly for providing relief from arthritis. At least one signal transmission element engagement member is operatively connected to the joint stabilizing assembly for connecting a signal transmission element. At least one signal transmission element is supported by the at least one signal transmission element engagement member. An electrostimulation unit, electrically connected to the signal transmission element produces a signal for improving the overall function of an arthritic joint. The electrostimulation unit used in conjunction with the joint stabilizing assembly for greater than 150 hours provides a synergistic effect, which results in optimized joint treatment versus using either the joint stabilizing assembly or electrostimulation unit alone. | 11-24-2011 |
20120016442 | REGULATION OF GENES VIA APPLICATION OF SPECIFIC AND SELECTIVE ELECTRICAL AND ELECTROMAGNETIC SIGNALS - Methods and devices for the regulation of gene expression by cells via the application of fields generated by specific and selective electric and electromagnetic signals so as to target diseased or injured tissue for treatment. By gene expression is meant the up regulation or down regulation of the process whereby specific portions (genes) of the human genome (DNA) are transcribed into mRNA and subsequently translated into protein. Methods and devices are provided for the targeted treatment of injured or diseased tissue that include providing specific and selective electric and electromagnetic signals and exposing tissue to the fields generated by the signals so as to regulate gene expression. In particular, methods and devices are provided for the targeted treatment of bone defects, osteoarthritis, osteoporosis, cancer, and other disease states. | 01-19-2012 |
20120059433 | SYSTEMS AND METHODS FOR IMPLANTABLE LEADLESS BONE STIMULATION - Systems and methods are disclosed to enhance bone growth by stimulating bone sites for bone regrowth, fusion, or grafts. The invention uses electrical stimulation of the bone site, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the bone site. The vibrational energy is generated by a controller-transmitter, which could be located either externally or implanted. The vibrational energy is received by a receiver-transmitter, which could be incorporated into an orthopedic device, such as pin, cage, plate or prosthetic joint used for bone healing. | 03-08-2012 |
20120059434 | Implantable Tissue Growth Stimulator - An implantable tissue growth stimulator is disclosed. The implantable tissue growth stimulator includes electronic circuitry to alter the voltage output by the stimulator. The implantable tissue growth stimulator may he controlled from an external device via wireless communication. The implantable tissue growth stimulator may be configured for use with an implants in particular, the implantable tissue growth stimulator may be incorporated into an orthopaedic device such as a hip prosthesis. The implantable. tissue growth stimulator may be used to stimulate bone growth. | 03-08-2012 |
20120191159 | METHOD AND DEVICE FOR TREATING OSTEOARTHRITIS NONINVASIVELY - Methods and devices are provided for OA treatment of an affected area or joint. In one embodiment, the method may involve identifying a treatment site of the joint, and providing at least one transducer module at the treatment site. The at least one transducer module may be in operative communication with a signal generator module, and may include transducer(s) for delivering stimulative signals (e.g., electromagnetic signals and/or ultrasound signals). The method may also involve stimulating (a) bone remodeling, (b) bone cells and associated precursors, and/or (c) pericytes with the stimulative signals delivered to the treatment site. | 07-26-2012 |
20120197344 | ELECTROSURGICAL SYSTEM AND METHOD FOR TREATING HARD BODY TISSUE - A method of preparing a target hard body tissue, such as osseous or dental tissue, to receive an implant component including; positioning an active electrode in proximity to a target tissue and proximate an electrically conductive fluid, followed by applying a high frequency voltage between the active electrode and a return electrode, the high frequency voltage sufficient to form a plasma. This plasma modifies at least a portion of the target tissue. An implant component may then be placed adjacent at least a portion of the modified target tissue. | 08-02-2012 |
20120215281 | IMPLANT DEVICE FOR STIMULATING OSTEOGENESIS AND OSSEOINTEGRATION - An implant device for stimulating osteogenesis and osseointegration comprises a hollow annular housing member, a pulsed current modulator, and a coil connected to the current modulator. The current modulator and at least a portion of the coil are mounted within the housing member. A frequency of the pulsed current is selected to generate an electromagnetic field of a predetermined flux density that penetrates, and propagates radially outwardly from, the housing member for a sufficiently large propagation distance to stimulate osteogenesis and osseointegration, by means of the generated electromagnetic field, of a bone region in which the implant device is implanted and which is disposed radially outwardly from the housing member. | 08-23-2012 |
20120283798 | ALVEOLAR BONE REGENERATIVE APPARATUS - Provided is an alveolar bone regenerative unit and an alveolar bone regenerative apparatus capable of regeneration treatment for an alveolar bone by sterilizing a periodontium and activating an osteoblast. The alveolar bone regenerative unit includes an active needle electrode of a metal electrode generating heat by power supply and a handle attached to a base of the active needle electrode. The active needle electrode is 25.0 to 41.0 mm long and 0.08 to 0.47 mm in diameter, on which a strippable coat is formed with silicon resin. Supplying power to the active needle electrode causes heat generation at a high temperature because of the thin diameter. The high temperature and electric energy can kill bacteria around a root, thereby being able to activate an osteoblast and regenerate an alveolar bone. | 11-08-2012 |
20130018437 | STIMULATION SYSTEM AND METHOD FOR TREATING FRAGILE BONE DISORDERS - According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a fragile bone disorder or condition. The system includes an electrical stimulation lead adapted for implantation into a subcutaneous area in communication with a predetermined site, wherein the site is neuronal tissue that is associated with C2/C3 dermatome area. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a fragile bone disorder or condition. | 01-17-2013 |
607052000 | With monitoring or testing feature | 2 |
20100121410 | BIOMECHANICAL-STIMULATION APPARATUS AND METHOD FOR BONE REGENERATION - The invention relates to a biomechanical stimulation apparatus for bone regeneration which comprises | 05-13-2010 |
20120330376 | SYSTEMS AND METHODS FOR MAKING AND USING ELECTRICAL STIMULATION SYSTEMS FOR PROVIDING THERAPY TO LARGE ANIMALS - An electrical stimulation system for providing non-invasive therapeutic stimulation to a large animal includes a surcingle for placement around a girth of the large animal. The surcingle includes a non-stretchable first element and a stretchable second element. Foam wedges are disposed on the first element for flanking a spine of the large animal during stimulation. A control module with a signal generator is coupleable to the first element. A treatment electrode is disposed on a lead that is electrically coupleable to the control module. The treatment electrode has a conductive inner surface for disposing over skin of the large animal at a target stimulation location. The treatment electrode transmits to the target stimulation location electrical signals received from the signal generator. A return electrode disposed on the first element is electrically coupled to the control module and receives electrical signals output from the treatment electrode. | 12-27-2012 |