| Entries |
| Document | Title | Date |
|---|
| 20080249487 | BLOOD LEAKAGE DETECTION DEVICE - A blood leakage detection device for attachment to the skin of a patient at a wound such as one caused by insertion a cannula into a vein or artery comprises a support of a flexible material having a top side and an opposite bottom side, a zone of adhesive for attachment to the skin on the bottom side of the support extending along its periphery except for a sector of from about 5° to about 150°, a blood absorbent patch disposed on the support and extending inwardly of the adhesive zone and, optionally, in the sector, and a blood detection probe comprising a probe head disposed at or near the centre of the support in the absorbent patch or abutting the bottom side thereof. A blood transport element can be disposed between the support and the absorbent patch. | 10-09-2008 |
| 20080262445 | Transdermal Delivery of Hydrophobic Bioactive Agents - A method and related compositions, including the use of N-acyl derivatives of sarcosine, provide for the delivery of bioactive agents through tissue surfaces such as the skin. The method and composition are particularly well suited for hydrophobic active agents such as serotonin (5HT | 10-23-2008 |
| 20090062754 | Transdermal drug delivery systems comprising a coated release liner - The present invention refers to a transdermal delivery device comprising a backing layer, at least one adhesive layer, and a release liner coated with a UV-cured highly crosslinked silicone. The present invention also refers to a method of preparing a transdermal delivery device comprising a backing layer, at least one adhesive layer, and a release liner coated with a UV-cured silicone. | 03-05-2009 |
| 20090088707 | DRESSING, METHOD AND KIT FOR SKIN CRACK REPAIR - The invention provides a dressing, method and kit components useful for effectively and conveniently treating skin cracks or other skin conditions requiring a moist healing environment. | 04-02-2009 |
| 20090234308 | Transdermal systems having control delivery system - Transdermal delivery systems are disclosed including a backing layer, a polymer membrane within the backing layer, an adhesive layer for attaching the delivery system to the patient's skin or mucosa, and a releasable layer covering the adhesive layer prior to use, the polymer membrane impregnated with sufficient fluid medium to alter the rate of transmission of an active agent through the polymer membrane, with the amount of fluid medium being greater than the amount retained by the fluid membrane upon drying. | 09-17-2009 |
| 20090299304 | STABILIZED TRANSDERMAL DRUG DELIVERY SYSTEM - A solid dispersion transdermal drug delivery system comprising a therapeutic agent in a stable amorphous form and a combination polymeric stabilizing and dispersing agent having a hydrogen bond-forming functional group, and a method of manufacturing these systems is provided. The weight ratio of the combination polymeric stabilizing and dispersing agent to the therapeutic agent is also disclosed. | 12-03-2009 |
| 20100010458 | MAGGOT DEBRIDEMENT THERAPY DRESSINGS AND METHODS - Maggot debridement therapy dressing embodiments and methods are discussed for the treatment of a variety of indications including wound care, including septic wound care and the like. | 01-14-2010 |
| 20100222753 | Patch With Hydrophilic Adhesive - The invention concerns a patch ( | 09-02-2010 |
| 20100280467 | Adhesive Patch - An adhesive patch is provided that allows the user to apply it in a safe and hygienic manner without touching the drug-containing matrix during the sequence of actions from the removal of the liner to the application of the patch. Specifically, the adhesive patch has a multilayer structure that includes a backing, an adhesive drug-containing matrix that is spread substantially entirely over one surface of the backing, and a liner that adheres to the drug-containing matrix surface. The adhesive patches have the following features: | 11-04-2010 |
| 20100292660 | DERMAL DELIVERY DEVICE WITH ULTRASONIC WELD - A method of enclosing an active ingredient layer between a release liner and a backing layer of a dermal patch by ultrasonically welding a seal between the backing layer and the release liner. A pressure sensitive layer is further provided between the backing layer and release liner. | 11-18-2010 |
| 20100298788 | Adhesive Patch and Production Method Thereof - An adhesive patch, such as poultice-type patch, is provided, which is suitable for mass production and allows the user to apply it without touching the drug-containing matrix. A production method of such a adhesive patch is also provided. | 11-25-2010 |
| 20100305522 | FLUID MEDICATION DELIVERY DEVICE - A fluid delivery device for transdermal delivery of a fluid to a patient. The device comprises an envelope that may be applied to a patient's skin. The envelope comprises at least one diffusion layer coupled to at least one impermeable layer such that at least a chamber is defined therebetween. Other embodiments include internal diffusion layers, and thus possess additional chambers, as well. In one arrangement, an adhesive boundary layer permits the device to be removably secured to a patient and inhibits radial migration of fluid beyond the periphery of the device. In another arrangement, preferably, an anti-microbial layer is provided to inhibit the growth of microorganisms. | 12-02-2010 |
| 20100318042 | ADHESIVE PATCH - Provided is an adhesive patch including a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a woven fabric knitted in stockinette stitch on both sides having two or more rows of crimped polyethylene terephthalate multifilament yarns, the adhesive layer contains 25 to 50% by mass of a liquid organic ingredient and 25 to 50% by mass of a thermoplastic elastomer based on the total mass of the layer and contains 10% by mass or more of methyl salicylate as the liquid organic ingredient based on the total mass of the layer, and the storage elastic modulus (G′) of the adhesive layer is 30000 to 75000 Pa at 10 rad/s and 37° C. | 12-16-2010 |
| 20110071482 | DEVICES AND METHODS FOR SIGNALING WHEN ACTION IS DUE IN RELATION TO A MEDICAL DEVICE - Methods and devices for signaling to a subject or subject's care giver the occurrence of at least one event selected from: a) expiration or impending expiration of a predetermined time period and/or b) a change in a physiological or device-associated variable, associated with a medical device that is positioned on, in or connected to the subject's body. | 03-24-2011 |
| 20110125113 | TISSUE ENCLOSURE - Provided is a device for providing a vacuum to a tissue, including a first tissue cover for covering the tissue and having first peripheral portion with a tissue facing contact surface adapted to be sealingly affixed to a first tissue portion surrounding the tissue, the device being adapted for enabling a vacuum to be selectively applied to the tissue in operation of the device; a substantially contiguous layer of flowable sealing material configured for covering a second tissue portion abuttingly adjacent at least a part of the first peripheral portion, where the sealing material is configured for filling gaps between the contact surface and the first tissue portion that may form leaks, by flowing towards the contact surface under suction provided when the vacuum is applied to the damaged tissue in operation of the device, and where the sealing material is uncoupled with respect to the contact surface at least prior to affixing the contact surface to the first tissue portion; and a second tissue cover covering at least a part of the layer. The device may be provided in the form of a kit. A system and method including the device are also provided. | 05-26-2011 |
| 20110137269 | KIT FOR THE TREATMENT OF ONYCHOMYCOSIS - The invention concerns an occlusive or semi-occlusive dressing and a treatment kit for onychomycosis containing dressings according to the invention and a container of urea paste. | 06-09-2011 |
| 20110190716 | TRANSDERMAL DRUG DELIVERY DEVICE - There is disclosed a transdermal drug delivery device for the pre-treatment and treatment of poisoning by highly toxic organophosphates, in the form of a matrix system comprising a backing layer, a drug containing adhesive layer and a release liner, in which the drug containing adhesive layer comprises a neutral polyacrylate without functionality having a uniform dispersion of a parasympathomimetic and a parasympatholytic therein. | 08-04-2011 |
| 20110218506 | AMOROLFINE PATCH FOR THE TREATMENT OF ONYCHOMYCOSIS - A transungual patch/device useful for the treatment of onychomycosis includes:
| 09-08-2011 |
| 20110238021 | TRANSDERMAL DELIVERY DEVICE AND METHOD - A transdermal delivery device is provided for delivering at least one active therapeutic compound to rapidly induce a therapeutic effect, the device comprising: a pad for receiving a depot of the at least one therapeutic compound, the pad having a portion of material of high compression resistance; and the device also comprising a backing layer of greater cross-section than the pad. A method for rapidly reducing a therapeutic effect and a transdermal delivery but for delivering at least one therapeutic compound to rapidly induce a therapeutic effect are also provided. | 09-29-2011 |
| 20110288508 | BIOADHESIVE PATCH - The present invention relates to a moist, layered bioadhesive patch comprising one or more polymers. Moreover, the invention relates to a method of producing a monolayered film and a method of drying said film. Additionally, the invention relates to methods of producing bioadhesive, layered patches by combining layers of the monolayered film to obtain a desired thickness of the patch. Patches according to the invention may be used as such, or for delivering pharmaceutically active compounds, such as in a drug delivery system. | 11-24-2011 |
| 20120022474 | PLASTER WITH MEDICATION DISPENSER - An adhesive plaster ( | 01-26-2012 |
| 20120029447 | TRANSDERMAL PHARMACEUTICAL PREPARATION AND ADMINISTRATION OF TIROFIBAN - The present invention provides a titratable transdermal drug delivery system comprising an effective dose of an antithrombotic agent, such as tirofiban, or a pharmaceutically acceptable salt thereof. The dosage of the drug delivered is proportional to the size of the patch applied and achieves 60-85% platelet inhibition. The system enables and individualized treatment for patients. Also provided are methods for the treatment of various disorders where platelet inhibition is desired. | 02-02-2012 |
| 20120089105 | SELF-ADHESIVE SKIN PATCH AND COMBINATION SET FOR COSMETIC SKIN CARE - The present invention relates to a skin patch comprising a matrix adhering to the skin and containing at least one active cosmetic substance and a combination with a skin wrapping to generate an effective compression for the treatment of cellulite and/or striae. | 04-12-2012 |
| 20120197221 | TRANSEPIDERMAL DRUG DELIVERY SYSTEM CONTAINING RIVASTIGMINE - Disclosed is a pharmaceutical composition containing rivastigmine. Specifically, disclosed is a transepidermal drug delivery system including a rivastigmine-containing drug layer and a supporter adhered to one surface of the drug layer to support the drug layer, wherein the drug layer contains 10 to 40 parts by weight of a rubber, 20 to 80 parts by weight of a rosin ester resin and 0.1 to 10 parts by weight of an acrylic adhesive and the drug layer has a thickness of 40 μm to 100 μm. | 08-02-2012 |
| 20120209223 | TRANSDERMAL THERAPEUTIC SYSTEM FOR ADMINISTRATION OF FENTANYL OR AN ANALOG THEREOF - Disclosed is a transdermal therapeutic system for administering an active ingredient through the skin comprising:
| 08-16-2012 |
| 20120220962 | TRANSDERMAL AND TOPICAL ADMINISTRATION OF VITAMINS USING BASIC PERMEATION ENHANCERS - Methods are provided for enhancing the permeability of skin or mucosal tissue to topical or transdermal application of pharmacologically or cosmeceutically active agents. The methods entail the use of a base in order to increase the flux of the active agent through a body surface while minimizing the organic base. Compositions and transdermal systems are also described. | 08-30-2012 |
| 20120226245 | TRANSDERMALLY ABSORBABLE PREPARATION - Disclosed is a transdermally absorbable preparation, in which an adhesive agent produced by crosslinking at least one copolymer is contained in an adhesive layer and the aging period in the production of the adhesive layer can be shortened. The transdermally absorbable preparation comprises a support and an adhesive layer arranged on the support and containing an adhesive agent and a medicinal component. The transdermally absorbable preparation is characterized in that the adhesive agent comprises a resin mixture comprising 100 parts by mass of a specific acrylic copolymer (A) and 0.1 to 30 parts by mass of a specific acrylic copolymer (B) or 0.05 to 2 part(s) by mass of a polyamine compound, and the adhesive layer additionally contains an organic acid. | 09-06-2012 |
| 20120265158 | Transdermal Patch Formulation - A method for preparing a transdermal patch comprising a substrate layer is provided, the method comprising the steps of contacting an active pharmaceutical ingredient with a retaining means to provide a composition, applying the composition obtained in step (a) to a carrier material to form a substrate layer of the transdermal patch, wherein the retaining means remain within the final transdermal patch. | 10-18-2012 |
| 20120283671 | ANTI-INFLAMMATORY ANALGESIC ADHESIVE PATCH FOR EXTERNAL USE - An external patch containing diclofenac hydroxyethylpyrrolidine prepared by laminating an adhesive layer on a backing, wherein said adhesive layer is characterized by comprising 5-50% by weight of styrene•isoprene•styrene block copolymer, 20-50% by weight of a tackifier resin, 5-70% by weight of a softening agent, and 0.5-20% by weight of one or more solubilizers selected from N-methyl-2-pyrrolidone, propylene glycol and dimethyl sulfoxide as essential ingredients, and 0.5-20% by weight of diclofenac hydroxyethylpyrrolidine as an active ingredient. The patch has excellent transdermal absorption, less skin-irritation and excellent stability of the drug. | 11-08-2012 |
| 20120302974 | NIPPLE COVER - One aspect of the present application relates to a covering member for a protruding portion of a patient's body. This cover is flexible and collapsible so that it conforms to the shape of the encased portion of the body. | 11-29-2012 |
| 20120310187 | TRANSPARENT TRANSDERMAL NICOTINE DELIVERY DEVICES - A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%. | 12-06-2012 |
| 20120316519 | Tape Preparation - A tape preparation is provided which does not use a backing such as a plastic film, knit or a woven fabric, or a nonwoven fabric, has very high conformability to skin, and is easy to use at the time of application. There is provided a tape preparation | 12-13-2012 |
| 20120316520 | TRANSDERMAL THERAPEUTIC SYSTEM FOR ADMINISTERING LIPOPHILIC AND/OR SPARINGLY SKIN-PERMEABLE ACTIVE SUBSTANCES - A transdermal therapeutic system for administering lipophilic, poorly water-soluble and/or sparingly skin-permeable pharmaceutical active substances. The active substance is present in a multi-component enhancer system consisting of 4 components and each component of the multi-component enhancer system is selected from a different one of the substance groups: a) terpenes, b) cyclic glucitol ethers, c) medium-chain triglycerides of capric and caprylic acid and/or of linoleic acid; and d) longer-chain alcohols having a chain length of 8 or more carbon atoms. | 12-13-2012 |
| 20120323190 | Percutaneous Absorption Preparation Comprising Anti-Dementia Drug - The present invention relates to a percutaneous absorption preparation which can administer an anti-dementia drug stably and efficiently for a long period such as one week. More specifically, the present invention relates to a percutaneous absorption preparation comprising a drug-containing layer comprising an anti-dementia drug, a polymer compound having an amino group, a polyhydric alcohol fatty acid ester, a polyhydric alcohol, a polyvalent carboxylate ester, and a styrenic polymer compound. | 12-20-2012 |
| 20120323191 | ADHESIVE SKIN PATCH - The invention is intended to provide an adhesive patch which contains a drug except bisoprolol and which effectively inhibits the occurrence of oozing out or sticking out of the adhesive layer components from the exposed area of the adhesive layer of the adhesive patch during storage as well as the occurrence of oozing out of the drug from the adhesive layer thereby preventing the reduction in drug content. The support, the release liner and the adhesive layer constituting the adhesive patch each are formed to have a rectangular planar shape and the entire adhesive patch are formed to have a rectangular planar shape, and a protrudent part is formed on the support-side surface of the adhesive patch at a corner thereof. In addition, the adhesive patch may be formed to have a middle part and a peripheral part, and the protrudent part may be formed at a corner of the rectangular middle part. Further, between the adjacent at least two protrudent parts, a connecting built-up part may be provided in which the thickness of the adhesive patch is smaller than the thickness of the adhesive patch in the protrudent part. In case where the release liner has a split part, the split part is made so as not to traverse the protrudent part. | 12-20-2012 |
| 20130006203 | ADHESIVE PATCH CONTAINING BISOPROLOL - The invention is intended to provide an adhesive patch which effectively inhibits the occurrence of oozing out or sticking out of the adhesive layer components from the exposed area of the adhesive layer of the adhesive patch during storage as well as the occurrence of oozing of bisoprolol or a salt thereof from the adhesive layer thereby preventing the reduction in drug content. The support, the release liner and the adhesive layer constituting the adhesive patch each are formed to have a rectangular planar shape and the entire adhesive patch are formed to have a rectangular planar shape, and a protrudent part is formed on the support-side surface of the adhesive patch at a corner thereof. In addition, the adhesive patch may be formed to have a middle part and a peripheral part, and the protrudent part may be formed at a corner of the rectangular middle part. Further, between the adjacent at least two protrudent parts, a connecting built-up part may be provided in which the thickness of the adhesive patch is smaller than the thickness of the adhesive patch in the protrudent part. In case where the release liner has a split part, the split part is made so as not to traverse the protrudent part. | 01-03-2013 |
| 20130018334 | Biodegradable wound care products with biocompatible artificial skin treatment and healing acceleratorAANM Glynn; Kenneth P.AACI FlemingtonAAST NJAACO USAAGP Glynn; Kenneth P. Flemington NJ USAANM Martin; AlainAACI RingoesAAST NJAACO USAAGP Martin; Alain Ringoes NJ US - A biodegradable wound care product with biocompatible artificial skin treatment. It includes a biodegradable bandage support member and a biodegradable adhesive on at least a portion thereof. The support member is made of a biodegradable material, such as natural or artificial textiles, plastics or papers. A biodegradable actives carrier is attached to a portion of the biodegradable bandage support member and is a synthetic or natural biodegradable adhesive or a combination thereof. An active ingredient is located on the biodegradable actives carrier including a layer of biocompatible algae artificial skin including sterilized water and at least 60% by weight of reconstituted seaweed, preferably Laminaria seaweed. A healing accelerator that is an alpha keto acid or an alpha keto acid derivative is also included. The active ingredient is prepared by first drying the raw materials, converting the raw materials to a powder and then reconstituting the powder with sterilizes water and other possible actives and/or inerts. | 01-17-2013 |
| 20130018335 | NOVEL BANDAGE INCLUDING AGGLOMERATES OF PARTICLES SUITABLE FOR RAPIDLY GELLING OR SOLUBILISINGAANM Pernot; Jean-MarcAACI DijonAACO FRAAGP Pernot; Jean-Marc Dijon FR - The present invention relates to a bandage including an adhesive hydrocolloid mass, wherein said bandage includes, on at least one portion of the surface of the adhesive mass intended for being in contract with the wound when the bandage is being used, a plurality of agglomerates made up of particles linked to one another, preferably in a multi-layer configuration, at least 90% and preferably at least 95% of said particles being made up of one (or more) material(s) selected among polysaccharides, proteins and synthetic polymers, and being suitable for solubilizing or gelling in under ten seconds, and preferably still in less than one second when in contact with the exudate from the wound. The bandage according to the invention is intended for treating wounds such as blisters, exuding wounds, burns and dermal-epidermal lesions, whether superficial, deep, chronic or acute. | 01-17-2013 |
| 20130018336 | NOVEL DRESSING INCLUDING A WEB OF MICROFIBERS OR NANOFIBERS SUITABLE FOR GELLING OR SOLUBILIZINGAANM Pernot; Jean-MarcAACI DijonAACO FRAAGP Pernot; Jean-Marc Dijon FR - The present invention relates to a repositionable bandage including an adhesive hydrocolloid mass, wherein said bandage includes, on at least one portion of the surface of the adhesive mass intended for being in contract with the wound when the bandage is being used, a web of microfibers or nanofibers, at least 90% and preferably at least 95% of which being made up of one (or more) material(s) selected among natural or synthetic polymers, and being suitable for solubilizing or gelling in under ten seconds, and preferably still in less than one second when in contact with the exudate from the wound. The bandage according to the invention is intended for treating wounds such as blisters, exuding wounds, burns and dermal-epidermal lesions, whether superficial, deep, chronic or acute. | 01-17-2013 |
| 20130018337 | DERMAL DELIVERY DEVICE WITH IN SITU SEAL - This invention relates to a transdermal drug delivery device that comprises an active ingredient (AI) layer, having a skin contacting surface and a non-skin contacting surface and comprising a volatile component, a release liner impermeable to the volatile component adjacent the skin contacting surface of the Al layer having a perimeter that extends beyond the perimeter of the AI layer in all directions, and an overlay comprising a pressure sensitive adhesive (PSA) that does not absorb the volatile component adjacent the non-skin contacting surface of the Al layer having a perimeter of which extends beyond the perimeter of the Al layer in all directions, wherein the release liner and the PSA of the overlay are in contact with and adhered to each other around the perimeter of the Al layer to form a seal that reduces or prevents volatile component loss. | 01-17-2013 |
| 20130023839 | PATCH PREPARATION - The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability and in anchoring property of its drug-containing pressure-sensitive adhesive layer, and has a preferred patch feeling. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 μm to 16 μm; and the pressure-sensitive adhesive layer is laminated on the polyester nonwoven fabric layer. | 01-24-2013 |
| 20130046257 | METHODS OF USING AGENTS THAT MODULATE CLAUDIN EXPRESSION - This invention relates to the use of agents that modulate claudin-1 and/or -23 expression or activity for purposes of regulating tight junction (“TJ”) formation among keratinocytes that express claudin-1 and/or -23, or other cell types that over- or under-express claudin-1 and/or -23. Several aspects of the present invention relate to increasing claudin-1 and/or -23 expression or function to enhance tight junction formation among claudin-1 and/or -23 expressing cells, particularly keratinocyte and antigen presenting cells. Several other aspects of the invention relate to decreasing claudin-1 and/or -23 expression or function to diminish tight junction formation among claudin-1 and/or -23 expressing cells, particularly keratinocytes and antigen presenting cells. Transdermal drug and vaccine formulations including agent(s) that decrease -1 and/or -23 expression or function to diminish tight junction formation among claudin-1 and/or -23 expressing cells, as well as a trans dermal patch for delivering the same, are also included. | 02-21-2013 |
| 20130060209 | Athletic Tape - Adhesive tape for use in connection with treatment of injuries is described. Tape may be configured to relieve pressure and increase circulation at the injury site, as well as deliver a topical drug solution, including NSAID solutions. Elements such as drug solutions, adhesive, water soluble gels, and so forth may be disposed in patterns configured to increase efficacy and user comfort. | 03-07-2013 |
| 20130138055 | SPECIALLY-SHAPED BANDAGES FOR TREATING WARTS ON HUMAN DIGITS - A bandage is described comprising a rubber-based adhesive and a flexible substrate that is particularly adapted for application onto warts located on the ends of human digits. The flexible substrate is waterproof, skin-colored and shaped in various ways so as to securely attach onto the ends of human fingers and toes. The shape of the bandage promotes long-term use of the bandage to induce the body's inflammatory response and to prevent transmission of the wart virus to other persons. | 05-30-2013 |
| 20130138056 | NONAQUEOUS PRESSURE-SENSITIVE ADHESIVE FOR MEDICINAL TAPE PREPARATION FOR PERCUTANEOUS ABSORPTION, MEDICINAL TAPE PREPARATION FOR PERCUTANEOUS ABSORPTION, AND PROCESS FOR PRODUCING THE SAME - The present invention is directed to a nonaqueous pressure-sensitive adhesive that may be used in medicinal tape preparations for percutaneous absorption. The adhesive may comprise a copolymer obtained by copolymerization of a (meth)acrylic monomer having an acetoacetyl group in the molecule and one or more monomers from among other (meth)acrylic monomers without acetoacetyl groups and copolymerizable vinyl monomers, in a nonaqueous solvent. Suitable (meth)acrylic monomers having an acetoacetyl group in the molecule are acetoacetoxyalkyl methacrylates, and especially 2-acetoacetoxyethyl methacrylate. The pressure-sensitive adhesive of the invention uses no polyamine derivatives, isocyanate compounds, polyvalent metal chelate compounds, etc., as crosslinking agents, and therefore toxicity is not a concern and skin is not irritated. A medicinal tape preparation for percutaneous absorption of the invention has superior adhesive strength and cohesive strength, and is highly safe with low skin irritation. It also has excellent drug release and percutaneous absorption properties. | 05-30-2013 |
| 20130138057 | BACKING HAVING THREE-LAYER STRUCTURE AND AQUEOUS PATCH USING THE BACKING - The present invention relates to a backing having a three-layer structure prepared by sticking together an inner fiber layer for holding a pasty preparation, a film layer having through-holes, and an air-permeable outer fiber layer which prevents leaking out of the pasty preparation or a liquid component exuded from the pasty preparation, and also relates to an aqueous patch using the backing which can be applied for a long time. | 05-30-2013 |
| 20130144226 | MEDICAL ADHESIVE PATCH - A medical adhesive patch includes: a support film including a barrier layer which contains polyvinyl alcohol and a layered inorganic compound, and which is laminated on one surface of a support including polyurethane; an adhesive layer which contains a medicine, and which is laminated on the barrier layer of the support film, a degree of saponification of the polyvinyl alcohol is equal to or more than 70% and equal to or less than 95.5%. | 06-06-2013 |
| 20130165875 | TRANSDERMAL ABSORPTION PREPARATION - The present, invention relates to a transdermal absorption preparation. The transdermal absorption preparation of the present invention comprises a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant, and a transdermal absorption promoter. Also, the present invention provides a transdermal absorption preparation comprising a drug-containing adhesive layer, a drug-protective layer, and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, acrylic rubber, an anti-crystallisation agent, and a transdermal absorption promoter. When the transdermal absorption preparation of the present invention is used for the treatment of Parkinson's disease or restless leg syndrome, no side effect due to an increase in the initial drug concentration in blood occurs and the skin penetration effect of the drug is excellent. | 06-27-2013 |
| 20130165876 | PATCH PREPARATION - The present invention relates to a patch preparation having a central part and a peripheral part surrounding the central part, the patch preparation comprising: a patch preparation main body having a support and an adhesive layer which contains a drug and is formed on the support; and a release liner laminated on the adhesive layer, wherein the peripheral part has a predetermined area, and a peel force between the adhesive layer and the release liner in the predetermined area is greater than a peel force between the adhesive layer and a release liner in the central part. | 06-27-2013 |
| 20130184663 | MEDICAL ADHESIVE PATCH - A medical adhesive patch, includes: a support film including a barrier layer which contains a water-soluble polymer compound and montmorillonite, and which is laminated on one surface of a support including polyurethane; an adhesive layer which contains a medicine and a plasticizer, and which is laminated on a barrier layer of the support film, the medical adhesive patch has a percentage content of montmorillonite in the barrier layer is equal to or more than 2 percent by weight and equal to or less than 22 percent by weight. | 07-18-2013 |
| 20130211351 | Pharmaceutical patch for transdermal administration of (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4-b]indol]-4-amine - The invention relates to a pharmaceutical patch for transdermal administration of the pharmacologically active ingredient (1r,4r)-6′-fluro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4-b]indol]-4-amine or a physiologically acceptable salt thereof, the patch comprising a surface layer, an adhesive layer, and a removable protective layer, wherein the adhesive layer is located between the surface layer and the removable protective layer. | 08-15-2013 |
| 20130211352 | PERCUTANEOUSLY ABSORBED PREPARATION - The purpose of the invention is to produce an imidafenacin-containing percutaneously absorbed preparation, wherein the drug not only is not allowed to crystallize but also has adequate skin penetration. The imidafenacin-containing percutaneously absorbed preparation comprises isostearic acid and a fatty acid ester, which function as crystallization-preventing agents. | 08-15-2013 |
| 20130211353 | PERCUTANEOUS ABSORPTION TYPE FORMULATION - Provided is a percutaneous absorption type formulation of a drug such as imidafenacin and silodosin, wherein stable absorption through the skin is realized. The percutaneous absorption type formulation containing a drug such as imidafenacin and silodosin further contains a transdermal absorption promoting agent, and fatty acid ester and/or fatty acid amide that further improve(s) the function of the transdermal absorption promoting agent. | 08-15-2013 |
| 20130226112 | PERCUTANEOUS ABSORBENT AND ADHESIVE SHEET FOR SKIN PATCH - The invention provides an adhesive sheet for adhesion to the skin, as well as a transdermal absorption preparation containing the adhesive sheet and a drug or a pharmaceutically acceptable salt thereof in the adhesive layer of the adhesive sheet. The adhesive sheet comprises a support and an adhesive layer formed on the support, wherein the adhesive layer contains at least a thermoplastic elastomer, and more than 300 parts by weight of liquid paraffin per 100 parts by weight of the elastomer, and wherein the adhesive layer contains not more than 10 wt % of a tackifier. | 08-29-2013 |
| 20130226113 | UV STABLE TRANSDERMAL THERAPEUTIC PLASTER WITH A UV ABSORBING ADHESIVE LAYER SEPARATED FROM THE DRUG MATRIX - The invention relates to a UV stable transdermal therapeutic system (TTS) consisting of a back layer, at least one matrix containing an active substance and optionally, a withdrawal film and an UV-radiation absorber. An adhesive layer containing said UV-radiation absorber is arranged between the back layer and the matrix containing an active substance which is distant as much as possible from a surface, a separation layer is arranged between the adhesive layer containing said UV-radiation absorber and the matrix containing an active substance, which is as remote as possible from the surface which is impermeable to the active substance and UV-radiation absorber. The inventive transdermal therapeutic system exhibits a high stability and is devoid of inconveniences of existing TTS containing a light-sensitive substance. | 08-29-2013 |
| 20130261571 | Transdermal Therapeutic System For Administering Rivastigmine Or Derivatives Thereof - The present invention relates to a transdermal therapeutic system for administering an active substance through the skin, comprising:
| 10-03-2013 |
| 20130261572 | PATCH - Disclosed is a patch which is a formulation including deposited clonidine crystals and provides stable transdermal absorbability even after storage at varying temperatures. The patch disclosed includes a backing and a medicated layer integrally superposed on one surface of the backing. The medicated layer contains: 5 to 30% by weight of clonidine including clonidine in a crystallized state; 25 to 90% by weight of a macromolecular base (A) having a viscosity-average molecular weight of 800,000 or larger; and 5 to 60% by weight of a liquid additive capable of dissolving the clonidine. The weight ratio of the liquid additive to the macromolecular base (A) [the liquid additive/the macromolecular base (A)] is 0.1 to 2.0. | 10-03-2013 |
| 20130267916 | PERCUTANEOUS ABSORPTION PREPARATION CONTAINING RIVASTIGMINE - Disclosed is a percutaneous absorption preparation for treatment of dementia that comprises rivastigmine or its pharmaceutically acceptable salt as an active ingredient, a styrene-isoprene-styrene block copolymer, a tackifier resin, and a plasticizer, which preparation contains a small amount of rivastigmine but allows a sufficient amount of the active ingredient penetrated into the skin to achieve an effective treatment of dementia. | 10-10-2013 |
| 20130274694 | TRANSDERMAL PATCH INCORPORATING ACTIVE AGENT MIGRATION BARRIER LAYER - Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween. | 10-17-2013 |
| 20130281944 | TRANSDERMAL THERAPEUTIC SYSTEM (TTS) COMPRISING ROTIGOTINE - The present invention relates to a patch containing the active ingredient rotigotine for the transdermal delivery of the active pharmaceutical agent rotigotine, comprising a backing layer (1), a matrix layer (2) containing the active ingredient, and a removable protective sheet (4) which is intended for removal before the patch is applied to the skin, characterized in that disposed with areal coverage between the matrix layer (2) and the removable protective sheet (4) is an additional interlayer (3). | 10-24-2013 |
| 20130304002 | SHEET AND LIQUID COMBINATION SYSTEMS FOR DERMAL DRUG DELIVERY - A dermal drug delivery system is provided which comprises at least two components, for example, a sheet of a solid and flexible material, and a vehicle liquid comprising a solvent and optionally other ingredients. A drug, which can be unstable in said solvent but needs the solvent for being delivered into the skin, can be impregnated in the sheet. Other ingredients, such as agents for fastening the drug on the sheet can also be impregnated in the sheet. These two components may be stored separately and joined either shortly before or at the time of application. To use the system, the vehicle liquid may be applied either on the target skin area or on the sheet, and the sheet may then be applied on the target skin area so that the vehicle liquid is positioned between the sheet and the skin and brought into contact with the ingredients impregnated in the sheet. After the sheet and the vehicle liquid are combined in this way, the ingredients in the sheet and in the vehicle liquid are joined to form a combined formulation that is capable of delivering a drug through the skin at a desired rate. The sheet may have low enough permeability to the solvent or its vapor to control the time it takes for the solvent to evaporate across the sheet. When an appropriate local anesthetic agent, such as a tetracaine, is the drug, some embodiments of the system can have wide applications in anesthesia and pain control. | 11-14-2013 |
| 20130310777 | PATCH AND PATCH PREPARATION - The invention provides a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bloom even when an organic fluid component having high polarity is contained therein. The patch contains a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 500,000-1,600,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug. | 11-21-2013 |
| 20130317461 | COMPOSITIONS AND METHODS FOR DELIVERING ESTRADIOL IN TRANSDERMAL DRUG DELIVERY SYSTEMS - A blend of at least two polymers in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. | 11-28-2013 |
| 20130324950 | TRANSDERMAL DELIVERY SYSTEM CONTAINING GALANTAMINE OR SALTS THEREOF - The present invention provides a transdermal delivery system, which comprises a drug-containing matrix layer comprising: galantamine or its pharmaceutically acceptable salt as an active ingredient; and a styrene-butadiene-styrene copolymer or a styrene-isoprene-styrene copolymer as an adhesive. | 12-05-2013 |
| 20130331803 | TRANSDERMAL THERAPEUTIC SYSTEM COMPRISING BUPRENORPHINE - The invention is concerned with a transdermal therapeutic system (TTS) comprising buprenorphine and a method of manufacturing such a TTS. The transdermal therapeutic system is used for the transdermal administration of buprenorphine and analogues thereof. In particular, the invention relates to the use of a transdermal therapeutic system (TTS) for analgesic purposes. The TTS according to the invention comprises a transdermal drug delivery composition comprising buprenorphine and an adhesive component, which is a mixture of a crosslinked and a non-crosslinked acrylic polymer and a penetration enhancer comprising a keto acid. | 12-12-2013 |
| 20140005617 | FENTANYL TRANSDERMAL PATCH | 01-02-2014 |
| 20140018751 | Transdermal therapeutic system with crystallization-inhibiting protective film (Release liner) - The invention relates to pharmaceutical formulations, in particular to transdermal therapeutic systems, which are characterized in that little or no active ingredient crystallizes out at the interface between the removable protective film (release liner) and the active-ingredient-containing matrix. | 01-16-2014 |
| 20140031770 | TRANSDERMAL PATCH - The transdermal patch contains a base layer, a textured pharmaceutical layer, and a detachable layer, sequentially stacked from top to bottom. The textured pharmaceutical layer contains pressure-sensitive adhesive and medicament, and is configured with at least an embossed pattern for contacting with the skin. After the detachable layer is peeled off from the textured pharmaceutical layer and the latter is attached to the skin, the transfer performance of the contained medicament is significantly enhanced by the embossed pattern's increased area of release to the medicament. | 01-30-2014 |
| 20140052081 | DONEPEZIL TRANSDERMAL PATCH - The present invention relates to a donepezil transdermal patch comprising a backing layer and a pressure sensitive adhesive matrix layer, wherein the pressure sensitive adhesive matrix layer comprises donepezil free base and an acrylic pressure sensitive adhesive agent selected from the group consisting of a copolymer of 2-ethylhexyl acrylate and vinyl acetate and a copolymer of 2-ethylhexyl acrylate, vinyl acetate, and hydroxyl-containing monomers, and wherein 2-ethylhexyl acrylate is present in an amount of about 65% to about 75%, vinyl acetate is present in an amount of about 25% to about 35%, and the hydroxyl-containing monomers are in an amount of about 0% to about 10%, based on the total weight of the copolymer. | 02-20-2014 |
| 20140066865 | PATCH PREPARATION - The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability, and has a preferred handleability. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 μm to 16 μm; and the pressure-sensitive adhesive layer is laminated on the polyester base layer. | 03-06-2014 |
| 20140066866 | METHOD FOR HANDLING ADHESIVE LAMINATE SECTIONS - A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method. | 03-06-2014 |
| 20140081223 | Medicated Patch - A medicated patch is provided which is covered with a liner that enables one to remove the liner unconsciously and readily without losing the initial stickiness of the medicated patch. The external medicated patch includes a backing, an aqueous adhesive drug-containing matrix that is spread substantially entirely over one surface of the backing, and a liner that is larger in size than the surface of the drug-containing matrix to which the liner is attached. The liner larger in size than the surface of the drug-containing matrix to which the liner is attached includes an unattached area that extends from the surface of the drug-containing matrix, or an unattached slack portion that projects upward from the surface of the drug-containing matrix at a position on the surface of the drug-containing matrix. | 03-20-2014 |
| 20140100537 | TRANSDERMAL PHARMACEUTICAL PREPARATION AND ADMINISTRATION OF TIROFIBAN - The present invention provides a titratable transdermal drug delivery system comprising an effective dose of an antithrombotic agent, such as tirofiban, or a pharmaceutically acceptable salt thereof. The dosage of the drug delivered is proportional to the size of the patch applied and achieves 60-85% platelet inhibition. The system enables and individualized treatment for patients. Also provided are methods for the treatment of various disorders where platelet inhibition is desired. | 04-10-2014 |
| 20140155843 | THERAPEUTIC DELIVERY SYSTEM - Therapeutic delivery systems are provided which, in a first embodiment, contain a plurality of multiphase capsules in which first and second therapeutic agents are contained in separate phases within said multiphase capsules, and are disposed to deliver said first and therapeutic agents by at least two different delivery mechanisms. | 06-05-2014 |
| 20140155844 | ANTIMICROBIAL BARRIER DEVICE - The invention relates to an antimicrobial barrier device and methods of manufacture. The antimicrobial barrier comprises one or more antimicrobial drugs that inhibit biofilm formation and bacterial and/or fungal growth. The antimicrobial barrier is suited for use with insertable devices (e.g., catheters) to reduce the incidence of infection at and around the insertion site. | 06-05-2014 |
| 20140155845 | APPLICATION AID - The invention relates to a transdermal therapeutic system ( | 06-05-2014 |
| 20140171886 | Patch for Treatment of Eyelid Disease Containing Clobetasol - A patch for treatment of eyelid diseases that is provided with a support, a pressure-sensitive adhesive layer, and a release layer in this order, wherein (a) the pressure-sensitive adhesive layer includes the following (a-1) to (a-4): (a-1) a styrene-isoprene-styrene block copolymer, a tackifier resin, and a softening agent are contained; (a-2) a ratio (mass ratio) of the styrene-isoprene-styrene block copolymer and the tackifier resin is 1:2 to 1:4; (a-3) a content of the softening agent is 40% to 60% by mass; and (a-4) further 0.005% to 5% by mass of clobetasol or acid ester thereof is contained; and (b) the support has elastic modulus with a Young's modulus of 0.01 to 0.5 GPa: and a method for producing the patch for treatment of eyelid diseases including: forming a pressure-sensitive adhesive layer on a upper surface of a release layer. | 06-19-2014 |
| 20140188057 | TRANSDERMAL DOSAGE FORM FOR LOW-MELTING POINT ACTIVE AGENT - A drug-containing patch allows transdermal administration of a drug. The patch features a hydrophobic reservoir containing the drug, where the reservoir has a first surface and a second surface. A drug-impermeable backing overlies the first surface of the reservoir. A release sheet may overlie the second surface of the reservoir. The hydrophobic reservoir contains a drug and a hydrophobic matrix, where the hydrophobic matrix includes a hydrophobic filler in an amount which is effective to adsorb said drug; and a mixture of polyisobutylene and mineral oil. The hydrophobic matrix may contain hydrophobic colloidal silica as the hydrophobic filler. | 07-03-2014 |
| 20140200530 | TRANSDERMAL ESTROGEN DEVICE AND DELIVERY - Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described. | 07-17-2014 |
| 20140221942 | A Device for the Transdermal Delivery of Alkaline Compounds that are Susceptible to Degradation in Their Free Base Form - The present invention pertains generally to the field of transdermal drug delivery. More specifically, the invention relates to a device for the transdermal delivery of an alkaline pharmaceutically active compound that is susceptible to degradation in its free base form (e.g., rivastigmine) that comprises an adhesive matrix layer, a backing layer and a release or protective layer, wherein the adhesive matrix layer comprises said pharmaceutically active compound, triethylcitrate and hydrochloric acid. The invention also relates to methods of preparing such devices. | 08-07-2014 |
| 20140243764 | COMPOSITIONS AND METHODS FOR CONTROLLING DRUG LOSS AND DELIVERY IN TRANSDERMAL DRUG DELIVERY SYSTEMS - A transdermal delivery system is provided for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric and/or adhesive coating that is applied to either the transdermal system's backing or release liner. The transdermal delivery device is manufactured to optimize drug loading while providing desirable adhesion to skin or mucosa as well as providing modulation of the drug delivery and profile. | 08-28-2014 |
| 20140243765 | PERCUTANEOUSLY ABSORBABLE PREPARATION CONTAINING FENTANYL AND HOMOLOGUE THEREOF - Disclosed is a transdermal preparation, comprising sequentially-stacked layers of a backing layer, a barrier layer, a drug adhesive layer and a release layer, wherein the drug adhesive layer contains a drug selected from the group consisting of fentanyl, an analogue thereof and a pharmaceutically-acceptable salt thereof, a skin permeation enhancer of the drug, and a polyacrylate adhesive, which shows a high skin permeation with a low drug dosage, equivalent to one with high drug dosage, by increasing the skin permeation rate of drug. | 08-28-2014 |
| 20140249492 | TRANSDERMAL PATCH INCORPORATING ACTIVE AGENT MIGRATION BARRIER LAYER - Devices for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch. One outer layer functions as the primary adhesive layer for adhering the patch to the host. The other inner layer contains at least one active agent to be administered to the host. The inner layer is bonded to the outer layer through an opening provided in an interposed active agent impermeable release layer. The release layer separates a circumferential portion of the active agent containing inner layer from the outer adhesive layer to inhibit migration of the active agent therebetween. | 09-04-2014 |
| 20140276483 | TRANSDERMAL METHYLPHENIDATE COMPOSITIONS WITH ACRYLIC BLOCK COPOLYMERS - Described herein are transdermal compositions comprising methylphenidate in a polymer matrix comprising a non-reactive random acrylic polymer and an acrylic block copolymer. Method of making such compositions, and therapeutic methods using them also are disclosed. | 09-18-2014 |
| 20140276484 | Clay Composites and their Applications - Clay composite sheets, mats, films or membranes without polymers. Methods of preparing clay composite sheets, mats, films or membranes without using polymers in the method. Methods of using clay composite sheets, mats, films or membranes prepared without using polymers. Antimicrobial dressing having organo-modified clay product. Transdermal delivery of drugs using organo-modified clay product and methods. | 09-18-2014 |
| 20140303573 | DIAPERS, DIAPER WIPES AND DIAPER PADS WITH ACTIVE INGREDIENTS INTEGRATED THEREIN - A diaper, diaper sheet insert and/or a diaper wipe sheet with active ingredients integrated therein, including ointments for treating diaper rash, baby oils and lotions for treating dry skin, and/or powder treatments for absorbing moisture, including baby powder, corn starch powders and the like. In a first embodiment, the invention provides a diaper having active ingredients integrated therein comprising a skin-contact surface, at least one inner absorption layer, an outer most layer, and a barrier wall having an active ingredients segment and preventing contact of the active ingredients with the diaper's skin-contact surface. The active ingredient may be applied as a coating or integrated as fine particles within the barrier wall. As diaper is worn, or the active ingredient wipe sheet is wiped on the skin, the skin-contact surface comes into contact with skin, transferring active ingredients onto the skin. | 10-09-2014 |
| 20140303574 | ADHESIVE PATCH ASSEMBLY WITH OVERLAY LINER AND SYSTEM AND METHOD FOR MAKING SAME - An adhesive patch assembly and method for making same. The assembly can include an adhesive patch and a release liner. The patch can include a backing and a skin-contact adhesive. The release liner can further include a first portion and a second portion separated by a hinge. The first portion can be positioned to overlay the backing of the patch when the release liner is folded upon the hinge, and the second portion can be positioned to underlie the skin-contact adhesive of the patch. The method can include positioning the patch on the release liner, such that patch is located on one of the first portion and the second portion of the release liner; and folding the release liner about to locate the patch between the first portion and the second portion of the release liner. | 10-09-2014 |
| 20140323996 | Transdermal Therapeutic System for Administering an Active Substance - The present invention relates to a transdermal therapeutic system for administering an active substance through the skin, said system being suitable for an application period of at least three days, comprising the layers arranged in the following order with respect to each other:
| 10-30-2014 |
| 20140350493 | DERMAL DELIVERY DEVICE WITH IN SITU SEAL - This invention relates to a transdermal drug delivery device that comprises an active ingredient (AI) layer, having a skin contacting surface and a non-skin contacting surface and comprising a volatile component, a release liner impermeable to the volatile component adjacent the skin contacting surface of the Al layer having a perimeter that extends beyond the perimeter of the Al layer in all directions, and an overlay comprising a pressure sensitive adhesive (PSA) that does not absorb the volatile component adjacent the non-skin contacting surface of the Al layer having a perimeter of which extends beyond the perimeter of the Al layer in all directions, wherein the release liner and the PSA of the overlay are in contact with and adhered to each other around the perimeter of the Al layer to form a seal that reduces or prevents volatile component loss. | 11-27-2014 |
| 20140371692 | HYDROGEL COMPOSITIONS - Hydrogel compositions are provided (a) that have a continuous hydrophobic phase and a discontinuous hydrophilic phase, (b) that have a discontinuous hydrophilic phase and a continuous hydrophilic phase, or (c) that are entirely composed of a continuous hydrophilic phase. The hydrophobic phase, if present, is composed of a hydrophobic polymer, particularly a hydrophobic pressure-sensitive adhesive (PSA), a plasticizing elastomer, a tackifying resin, and an optional antioxidant. The discontinuous hydrophilic phase, if present, is composed of a crosslinked hydrophilic polymer, particularly a crosslinked cellulosic polymer such as crosslinked sodium carboxymethylcellulose. For those hydrogel compositions containing a continuous hydrophilic phase, the components of the phase include a cellulose ester composition or an acrylate polymer or copolymer, and a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding thereto. Films prepared from hydrogel compositions containing or entirely composed of the aforementioned continuous hydrophilic phase can be made translucent, and may be prepared using either melt extrusion or solution casting. A preferred use of the hydrogel compositions is in wound dressings, although numerous other uses are possible as well. | 12-18-2014 |
| 20140371693 | ADHESIVE PREPARATION - An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein
| 12-18-2014 |
| 20140378917 | TRANSDERMAL THERAPEUTIC SYSTEM WITH A LOW TENDENCY TO SPONTANEOUSLY CRYSTALLIZE - The present invention provides transdermal therapeutic systems for dispensing a pharmaceutical product, in particular a pharmaceutical product with a low tendency to spontaneously crystallize. The matrix layer or at least one of the matrix layers in said systems contains a silicone hot-melt adhesive, a pharmaceutical product, and particles made of crosslinked polyvinylpyrrolidone. The invention also relates to a method for producing said transdermal therapeutic systems. | 12-25-2014 |
| 20150018782 | TRANSDERMAL PATCH - A transdermal patch for the treatment of Alzheimer's disease includes: a backing, a rivastigmine-containing layer, a pressure-sensitive adhesive layer, and a release liner. In the transdermal patch, the rivastigmine-containing layer contains rivastigmine and an alkyl(meth)acrylate resin, the pressure-sensitive adhesive layer is composed of an acrylic pressure-sensitive adhesive containing a (meth)acrylic acid ester having a hydroxyl group, and neither the rivastigmine-containing layer nor the pressure-sensitive adhesive layer contains an anti-oxidizing agent. | 01-15-2015 |
| 20150025480 | COMPOSITION FOR THE TRANSDERMAL DELIVERY OF FENTANYL - A transdermal drug delivery composition comprises an acrylate copolymer and from about 8% to about 30% by weight fentanyl. A transdermal fentanyl delivery composition comprising methyl laurate or tetraglycol as a permeation enhancer is also provided. The transdermal drug delivery compositions can be used to make a transdermal drug delivery device for the delivery of fentanyl. | 01-22-2015 |
| 20150045749 | PERCUTANEOUS ABSORPTION PREPARATION CONTAINING DONEPEZIL, AND METHOD FOR PREPARING SAME - Provided is a transdermal delivery system (for example, in the form of a patch) having a double-layer structure including a drug-containing matrix layer and an adhesive layer, wherein the drug-containing matrix layer is obtained by completely dissolving donepezil using a certain polymer and then formulating along with an adhesive; and a process for preparing the same. The transdermal delivery system according to the present invention does not show any crystallization of donepezil in the formulation, can release donepezil at a uniform rate for a long time, and can inhibit the release dumping phenomenon that occurs in a transdermal delivery system having a single-layer structure. | 02-12-2015 |
| 20150051559 | TRANSDERMAL PATCH FOR TREATMENT OF DEMENTIA OR ALZHEIMER TYPE DEMENTIA - Disclosed is a transdermal patch for treatment of degenerative neurological disorders like dementia or Alzheimer type dementia. More particularly, the transdermal patch for treatment of neurodegenerative disorder comprises an adhesive monolayer which comprises Rivastigmine in free base form or its pharmaceutically acceptable salts, styrene block copolymer, and a tackifier, wherein total styrene units are in an amount of 4% w/w or more of said adhesive monolayer. | 02-19-2015 |
| 20150148758 | MIRTAZAPINE-CONTAINING TRANSDERMALLY-ABSORBABLE SKIN-ADHESIVE PREPARATION - The purpose is to provide a mirtazapine-containing transdermal patch capable of suppressing deposition of a crystalline component derived from mirtazapine, deterioration in sense of use, and deterioration in adhesiveness to the skin. The transdermal patch contains a support, a drug-containing layer and a release liner, and the drug-containing layer contains mirtazapine and an organic acid. | 05-28-2015 |
| 20150148759 | Pharmaceutical Patch for Transdermal Administration of Tapentadol - The invention relates to a pharmaceutical patch for transdermal administration of the pharmacologically active ingredient Tapentadol or a physiologically acceptable salt thereof, the patch comprising a surface layer, an adhesive layer which comprises a pressure sensitive adhesive and at least a portion of the total amount of the pharmacologically active ingredient that is contained in the pharmaceutical patch, and a removable protective layer, wherein the adhesive layer is located between the surface layer and the removable protective layer. | 05-28-2015 |
| 20150290142 | Multi-Day Patch for the Transdermal Administration of Rotigotine - The present invention relates to a transdermal therapeutic system, comprising (a) a backing layer, (b) a solvent-based self-adhesive matrix layer containing rotigotine as active ingredient, and (c) a release liner, wherein the self-adhesive matrix layer has a coating weight of about 75-400 g/m | 10-15-2015 |
| 20150335658 | UV STABLE TRANSDERMAL PLASTER - The invention relates to a UV stable transdermal therapeutic system (TTS) consisting of a back layer, at least one matrix containing an active substance and optionally, a withdrawal film and an UV-radiation absorber. An adhesive layer containing said UV-radiation absorber is arranged between the back layer and the matrix containing an active substance which is distant as much as possible from a surface, a separation layer is arranged between the adhesive layer containing said UV-radiation absorber and the matrix containing an active substance, which is as remote as possible from the surface which is impermeable to the active substance and UV-radiation absorber. The inventive transdermal therapeutic system exhibits a high stability and is devoid of inconveniences of existing TTS containing a light-sensitive substance. | 11-26-2015 |
| 20150366719 | METHODS AND DEVICES FOR SKIN TIGHTENING - The present invention relates to methods and devices for skin tightening after incising or excising tissue portions from a subject. Exemplary methods and devices include tunable dressings having an adhesive layer and a regulatable layer or an unstretched layer that responds to one or more external stimuli to contract or expand the dressing, where the contraction or expansion can be uniform or non-uniform. | 12-24-2015 |
| 20150374642 | TRANSDERMAL PATCH - A patch containing a storage layer retaining a drug or a pharmaceutically acceptable salt thereof and an adhesive layer which are formed on a support, wherein the adhesive layer contains a thermoplastic elastomer, and a non-volatile hydrocarbon oil in more than 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the adhesive layer optionally further contains a tackifier at a content of not more than 10 wt %. | 12-31-2015 |
| 20160038435 | TRANSDERMAL FORMULATIONS OF LAQUINIMOD - This invention provides a transdermal patch comprising a) a backing layer; b) a liner; c) optionally, a highly porous membrane; and d) a pharmaceutical composition comprising: (i) optionally, a pressure sensitive adhesive in an amount of up to about 95 wt % of the pharmaceutical composition, (ii) laquinimod in an amount of about 0.1-20 wt % of the pharmaceutical composition, and (iii) optionally, one or more permeation enhancers in a total amount of up to about 70 wt % of the pharmaceutical composition. This invention also provides a method for delivering laquinimod across the skin of the subject and for treating a human subject afflicted with a form of multiple sclerosis comprising administering to the skin of the subject a transdermal patch as described herein. This invention further provides a transdermal patch as described herein for use in treating a human subject afflicted with a form of multiple sclerosis. | 02-11-2016 |
| 20160045634 | Analgesic Formulation and Delivery Bandage - A medical dressing and analgesic formulation that is operable to provide pain relief to an injured area of the human body wherein the medical dressing is constructed so as to allow a user to create a customized size for each application of the medical dressing. The medical dressing further includes a body being planar in manner having a plurality of contiguous portions that are separated by a perforation. Each contiguous portion includes a medicament layer thereon that is operable to treat an injured are for pain. The contiguous portions in one embodiment of the medical dressing are further configured to be divisible into four quadrants wherein the user can select as few as one quadrant or more than one quadrant of each continuous portion so as to size the medical dressing to the appropriate size needed to treat the desired area of the body. | 02-18-2016 |
| 20160051489 | Propynylaminoindan Transdermal Compositions - Propynylaminoindan (e.g., Rasagiline) transdermal compositions are provided. Aspects of the transdermal compositions include a matrix which includes the propynylaminoindan, a pressure sensitive adhesive that includes an acrylate copolymer and a cationic acrylic copolymer. Also provided are methods of using the transdermal compositions and kits containing the transdermal compositions. | 02-25-2016 |
| 20160106892 | FLUIDIC CONNECTOR FOR IRRIGATION AND ASPIRATION OF WOUNDS - Disclosed herein are several embodiments of a negative pressure apparatus and methods of using the same in the treatment of wounds. Some embodiments are directed towards improved fluidic connectors configured to transmit irrigation fluid and to apply aspiration to a wound, for example using softer, kink-free conformable layers. Some embodiments may comprise a first channel for delivering irrigation fluid to the wound and a second channel for transmitting negative pressure and removing fluid comprising irrigation fluid and wound exudate from the wound, wherein the channels comprise a flexible spacer material. Some embodiments are directed toward an irrigation manifold attachable to or incorporated as part of a distal end of an irrigation and aspiration fluidic connector. | 04-21-2016 |
| 20160129229 | Moisturizing Finger Cover - An apparatus worn on the finger that can prevent cracked skin. In order to do so, the apparatus consists of a finger cover, an attachment mechanism, and a quantity of lotion. The finger is inserted into the finger cover through an open end. Next, the finger cover is secured with an attachment mechanism. When secured, the finger will be in contact with the quantity of lotion placed at a closed end of the finger cover. The finger cover is made of transparent plastic. As a result of being transparent, the finger cover has low visibility when worn. The apparatus can be worn when engaging in daily activities since the plastic is lightweight and durable. Since the finger cover is a loose fitting finger cover, the user can wear the apparatus comfortably. | 05-12-2016 |
| 20160143786 | FIBRIN-COATED WOUND DRESSING - A fibrin-coated wound dressing article having a flexible film layer, a pressure-sensitive adhesive layer disposed on the flexible film layer, and a fibrin powder layer disposed on a surface of the pressure-sensitive adhesive layer opposite the flexible film layer. Methods of making and using fibrin-coated wound dressing articles are included. | 05-26-2016 |
| 20160144067 | FILMS AND METHODS OF MANUFACTURE - Embodiments of the present disclosure are directed to perforated polymer films and methods of making the same. In some embodiments, the films are for use with implantable medical devices. In one embodiment there is a flexible body including a polymer film having a first surface and an opposing second surface, the film having a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by a one of the plurality of raised lips. In one embodiment, the film comprises a single layer, and in another embodiment, the film can comprise a plurality of layers. In certain embodiments, the film can comprise an adhesive layer. In another embodiment, one or more of the layers may be a drug containing layer and/or a rate controlling layer for drug release. | 05-26-2016 |
| 20160199314 | TOPICAL DRUG PATCH INCLUDING MICROSPHERES | 07-14-2016 |
| 20160199316 | THREE-LAYER TRANSDERMAL THERAPY SYSTEM (TTS) | 07-14-2016 |
| 20160250226 | DERMAL DELIVERY COMPOSITIONS AND METHODS | 09-01-2016 |
| 20160374956 | MULTILAYER TYPE PATCH - A multilayer-type patch comprising: a support layer; a drug reservoir layer; and an adhesive layer, wherein
| 12-29-2016 |
| 20160374957 | SLOW-RELEASE FORMULATIONS OF 5-HYDROXYTRYPTOPHAN AS AN ADJUNCT TO PRO-SEROTONERGIC THERAPIES - The present invention concerns the treatment of serotonergic dysregulation disordersand/or augmentation of serotonin levels in the brain by add-on treatments to serotonin enhancers, and slow-release formulations of 5-hydroxytryptophan (5-HTP) therefor. | 12-29-2016 |
