Class / Patent application number | Description | Number of patent applications / Date published |
604087000 | Means broken, cut, pierced or torn to permit mixing | 41 |
20080312588 | Cartridge For Storage and Delivery of a Two-Phase Compound - This invention finds application in the field of the devices and methods for physical or chemical mixing of products and particularly relates to a cartridge for storage and sterile delivery of a two-phase compound. The cartridge comprises a first tubular member ( | 12-18-2008 |
20090093757 | Mixing/Administration Syringe Devices, Protective Packaging and Methods of Protecting Syringe Handlers - A syringe device having a syringe barrel and a syringe piston having a container housing. At least a portion of the container housing is insertable within an internal chamber of the syringe barrel. A fluid passageway extends from the container housing through a piston stem. A method of protecting a syringe handler including providing the components of a syringe device and encasing the components in a protective film. The protective film is loose to allow manipulation of the syringe components relative to one another without opening or puncturing the film. Protective syringe device packaging that includes a laminate film of material sealed to encase the components of a syringe device containing a potentially harmful agent. | 04-09-2009 |
20090137951 | DEVICE FOR ADMINISTERING SEVERAL LIQUID MEDICINES TO A PATIENT - This device comprises a tube ( | 05-28-2009 |
20090254032 | MULTI-CHAMBER CONTAINER - The present invention relates to a multi-chamber medical bag, which is capable of obtaining a positive mixture of medicines, prior to the discharge thereof. A weak seal | 10-08-2009 |
20100191182 | Mixing Tool - The present invention provides devices and methods for mixing a formulation containing two or more constituents, such as a drug product and a diluent. The devices have a chamber for securing a container of the drug product. Various embodiments are presented. In one embodiment the device has two or more sides connected by a hinge, the two or more sides defining the chamber between them, and a handle for grasping and manipulating the device. In another embodiment the device has a housing with two or more side bars defining the chamber, the container being visible from outside the housing between the side bars and having a stopping element at the distal end, and a handle having two arms for grasping. | 07-29-2010 |
20100298768 | Pen Injection Device and Method of Using Same - Pen injection devices ( | 11-25-2010 |
20110087164 | DUAL CONTAINER FLUID TRANSFER DEVICE - A fluid transfer device is disclosed and described, the device comprising a housing comprising a first piercing assembly associated with the housing, the first piercing assembly adapted for accessing a first container, the first piercing assembly comprising a first piercing member comprising at least one conduit. A second piercing assembly is associated with the housing, the second piercing assembly adapted for accessing a second container, the second piercing assembly comprising a second piercing member comprising at least one conduit. | 04-14-2011 |
20110178459 | Multi-Chamber Mixture Dispensing System - Disclosed is a dispensing system a dispenser having a first chamber containing a first material and a second chamber containing a second material. The dispenser is configured to selectively retract one of the chambers at least partially within the other to transition the dispenser between an extended position and a compact position. The first chamber includes an open top end that is, before use, covered with a first breakable membrane. A breaker ring, at least initially covered with a second breakable membrane, is configured to break the breakable membranes when the dispenser is transitioned between an extended position and a compact position. In the compact position, with the membranes broken, the first material and second material are free to form a mixture that can be dispensed via an opening in the dispenser's openable tip. | 07-21-2011 |
20120016296 | AUTOINJECTOR WITH MIXING MEANS - An autoinjector comprising:
| 01-19-2012 |
20120035537 | SYSTEMS AND METHODS FOR COMBINING MATERIALS - A method of combining a drug in a first container and a liquid in a second container includes placing the first container and the second container in fluid communication with a housing, combining the liquid and the drug in the first container, transferring the liquid and the drug from the first container to the housing, and transferring the liquid and the drug from the housing to a third container. | 02-09-2012 |
20120109053 | Applicator Tip - An applicator tip for use with a fluid applicator includes a base configured for releasable engagement with a fluid applicator at a proximal end of the base. The base includes a chamber defined therein configured for retaining a mixing component therein. One or more penetrable members are disposed within the base to at least partially encloses the chamber to retain the mixing component therein. A shaft extends distally from the base and defines a longitudinal axis. The shaft has a lumen extending therethrough configured for passage of a fluid therethrough. Upon penetration of the penetrable member, fluid from the fluid applicator flows into the chamber such that the fluid and the mixing component form a mixture to be applied. | 05-03-2012 |
20120172793 | FIXTURING MEMBER AND DEVICE FOR PERMITTING MIXING IN A PEN INJECTOR - In one aspect, a fixturing member for fixing a source of flowable material relative to a pen injector so as to permit introduction of the flowable material into the pen injector is provided herein. The fixturing member includes a body having a web with opposing proximal and distal faces. A distal wall extends distally from the distal face of the web, with the distal wall at least partially encompassing a distal chamber. Features are formed on the body for removable mounting onto a pen injector. Also, features are formed on the body for mounting onto a source of flowable material, A cannula extends through the web the cannula having proximal and distal ends with a lumen extending therebetween. The distal end of the cannula is located in the distal chamber and positioned such that, with the member being mounted to a pen injector, the distal end is located to be in the pen injector. The proximal end of the cannula is located proximally of the proximally face of the web such that, with the member being mounted to a source of flowable material, the proximal end of the cannula is located to be in communication with the flowable material. Advantageously, with the subject invention, a fixturing member is provided which facilitates mixing of substances in a pen injector in preparing a pen injector for injection. | 07-05-2012 |
20120179096 | Locking Syringe System - The invention provides methods and apparatus for reconstituting fluids and substances and injecting the reconstituted materials. Apparatus may include an injection needle having a hub, a draw-up needle having a hub, and a safety cap for engagement with a syringe barrel or reservoir for transfer and/or reconstitution and injection of fluids. The apparatus includes engagement means for securely engaging the hubs of the needles and/or cap to minimise inadvertent pricks with either of the needles during the filling of a syringe with reconstituted materials and injecting the materials. Preferably the engagement means incorporates a channel on one hub and a protrusion on the other hub. The system may incorporate a second bore for quick draw-up of materials and fluids for injection. Preferably, the apparatus comprises of polymeric materials which can be injection moulded. The invention includes methods for drawing-up and reconstituting fluids for injection. | 07-12-2012 |
20120209171 | CARTRIDGE FOR POWDER AND LIQUID DRUG - A cartridge or injector for holding and mixing a medical product is provided herein including a tubular body having a cylindrical wall having first and second opposing ends. The wall includes inner and outer surfaces with the inner surface having a generally constant cross-section along at least a drug mixing area. A first stopper is slidably disposed within the wall between the first and second ends, the first stopper defining a liquid-tight seal with the inner surface. A second stopper is slidably disposed within the wall between the first stopper and the first end, the second stopper defining a liquid-tight seal with the inner surface. A flexible insert is disposed at or in proximity to the second end, the insert forming a liquid-tight seal with the wall, the insert being pierceable by a medical needle or other piercing instrument. A rigid retainer is fixed to the wall having an opening therein for providing access to the insert for piercing by a medical needle. The insert extends into the retainer and forms a liquid-tight seal across the opening. Advantageously, with the subject invention, a reconstitution assembly may be provided which has a sufficiently large distal opening during assembly which allows a dry component to be introduced into the device in a dry state. | 08-16-2012 |
20120209172 | Bone-Regeneration Material - The invention relates to a process for producing a bone-regeneration material. According to the method, a bio-compatible, open-pored body is exposed to a vacuum and osteoinductive and/or osteogenic substances are absorbed into the pores of the body, for example by means of a vacuum generated therein. It is thus possible to produce a bone-regeneration material, which contains osteoinductive and/or osteogenic substances in the pores of the bio-compatible body, said substances acting as a network structure for new somatic cells that are to grow into the porous body. | 08-16-2012 |
20120238951 | MULTI-CHAMBER MIXTURE DISPENSING SYSTEM - Disclosed is a dispensing system a dispenser having a first chamber containing a first material and a second chamber containing a second material. The dispenser is configured to selectively retract one of the chambers at least partially within the other to transition the dispenser between an extended position and a compact position. The first chamber includes an open top end that is, before use, covered with a first breakable membrane. A breaker ring, at least initially covered with a second breakable membrane, is configured to break the breakable membranes when the dispenser is transitioned between an extended position and a compact position. In the compact position, with the membranes broken, the first material and second material are free to form a mixture that can be dispensed via an opening in the dispenser's openable tip. | 09-20-2012 |
20120259279 | Buffering Agent Delivery System for Anesthetic Syringe - A syringe for dispensing anesthetic from a cartridge having an interior wall defining a hollow interior sized and shaped for receiving a dose of anesthetic, and a piston. The syringe includes a tubular plunger slidably received in the hollow interior of the tubular cartridge. The plunger has a hollow interior extending between a distal end shaped for engaging the piston and an open proximal end. The syringe includes a plunger rod slidably received in the hollow interior of the tubular plunger. The rod has a sharp distal end adapted to penetrate the piston, a proximal end, and a length extending between the distal end and the proximal end sized so a delivery portion of the rod extends through the piston into the cartridge when the rod is driven through the piston. The delivery portion includes a recess for receiving a buffering agent to reduce acidity of the dose of anesthetic. | 10-11-2012 |
20120323172 | INLINE LIQUID DRUG MEDICAL DEVICES WITH LINEAR DISPLACEABLE SLIDING FLOW CONTROL MEMBER - Inline liquid drug medical device having a longitudinal device axis, a housing with a linear displaceable sliding flow control member displaceable along a transverse bore from a first flow control position for establishing flow communication between a first pair of ports for liquid drug reconstitution purposes to a second flow control position for establishing flow communication between a second pair of ports for liquid drug administration purposes, and a manually operated actuating mechanism for applying a linear displacement force for urging the flow control member to slide along the bore from its first flow control position to its second flow control position. | 12-20-2012 |
20130110039 | SYRINGE CARPULE FOR STORING, TRANSPORTING AND IN SITU MIXING OF LIDOCAINE AND SODIUM BICARBONATE AND DELIVERY OF BUFFERED ANESTHETIC SOLUTION | 05-02-2013 |
20140005597 | KIT AND METHOD FOR USE IN ADMINISTERING THERAPEUTIC BOTULINUM TOXIN (BOTOX) | 01-02-2014 |
20140005598 | INTEGRATED PUNCTURE NEEDLE ADAPTER | 01-02-2014 |
20140012191 | VAGINAL HYGIENE SYSTEM - A device and kit are described for mixing and instillation of a two-part chemical system within a body cavity, under pressure. More particularly, a vaginal hygiene system is illustrated utilizing a two-part chemical system effective for achieving stasis of the vaginal flora, whereby bacterial vaginosis is effectively mitigated, thereby eliminating undesirable vaginal discharge and discomfort. In one embodiment a kit is described including a highly portable dispenser having separate and distinct reservoirs which segregate the two-part chemical system until the desired time of use, and further include a combination applicator nozzle and blending manifold, wherein activation of the device results in the fluidic coupling of the chemical reservoirs, and provides immediate intermixing of the two-part chemical system concomitant with pressurized expulsion through an imperforate nozzle into the vaginal canal. | 01-09-2014 |
20140039386 | Cefuroxime safety delivery system - The present invention relates to safety delivery systems for intracameral administration of an appropriate dose of cefuroxime subsequent to cataract and other eye surgery. A preferred embodiment of an cefuroxime safety delivery system according to the invention comprises (a) a perforable sterile vial sterile-filled with a measured amount of cefuroxime, (b) a reconstitution syringe with a male luer fitting sterile-filled with 0.1 ml of isotonic salt solution per mg cefuroxime in the perforable vial and a vial adapter with a female luer fitting or one or more needles with female luer fitting, and (c) one or more sterilized delivery syringes with male luer fitting, each delivery syringe being capable of holding at least 0.1 ml of ejectable liquid and containing a marking indicating a fill volume of 0.1 ml of ejectable liquid. | 02-06-2014 |
20140058319 | Compact Device For Rapidly Mixing and Delivering Substances To a Patient - Injection devices are disclosed for injections of substances. The disclosed devices separately may hold two separate substances, e.g., solid, liquid or gas substances, in separate compartments which are interrupted so that the separate substances come into contact during the activation of the device. One disclosed device includes a needle for injection and two substances that are mixed with only a few actions by the operator of the device. The device may or may not activate mixing by the removal of a sleeve which triggers compartment interaction through movement of pins, pegs, springs, wires, string, or other mechanisms which allow the materials held in separate chambers to come into contact with each other. Operator error during mixing and checking the dosage of substances to be injected is avoided with the disclosed devices. Also, the needle is maintained in a sterile state because the needle is held internally of the device until the sleeve is removed and the device begins to activate. | 02-27-2014 |
20140148758 | VAGINAL HYGIENE SYSTEM - A device and kit are described for mixing and instillation of a two-part chemical system within a body cavity, under pressure. More particularly, a vaginal hygiene system is illustrated utilizing a two-part chemical system effective for achieving stasis of the vaginal flora, whereby bacterial vaginosis is effectively mitigated, thereby eliminating undesirable vaginal discharge and discomfort. In one embodiment a kit is described including a highly portable dispenser having separate and distinct reservoirs which segregate the two-part chemical system until the desired time of use, and further include a combination applicator nozzle and blending manifold, wherein activation of the device results in the fluidic coupling of the chemical reservoirs, and provides immediate intermixing of the two-part chemical system concomitant with pressurized expulsion through an imperforate nozzle into the vaginal canal. | 05-29-2014 |
20140221918 | Buffering Agent Delivery System for Anesthetic Syringe - A syringe for dispensing anesthetic from a cartridge having an interior wall defining a hollow interior sized and shaped for receiving a dose of anesthetic, and a piston. The syringe includes a tubular plunger slidably received in the hollow interior of the tubular cartridge. The plunger has a hollow interior extending between a distal end shaped for engaging the piston and an open proximal end. The syringe includes a plunger rod slidably received in the hollow interior of the tubular plunger. The rod has a sharp distal end adapted to penetrate the piston, a proximal end, and a length extending between the distal end and the proximal end sized so a delivery portion of the rod extends through the piston into the cartridge when the rod is driven through the piston. The delivery portion includes a recess for receiving a buffering agent to reduce acidity of the dose of anesthetic. | 08-07-2014 |
20150094651 | SYSTEM AND METHOD FOR DELIVERY OF BIOLOGIC AGENTS - A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen. | 04-02-2015 |
20150112252 | DISPENSE INTERFACE - The invention provides a dispense interface for an ejection device comprising a first part and a second part, at least a first opening, a second opening and a third opening, a fluidic channel and a connection element for each of the openings, wherein the first part is joined to said second part to form at least a part of said fluidic channel connecting said openings with each other and wherein each connection element is configured to accept a needle assembly for a fluid tight connection with said corresponding opening in order to reduce the complexity and provide an easy usage of the dispense interface and at the same time overcome the problems of material compatibility and cross contamination. The invention also relates to a system comprising a dispense interface according to the invention and a needle assembly for each opening. Furthermore, the invention relates to a method for preparing a dispense interface according to the invention. | 04-23-2015 |
20150112253 | DISPENSE INTERFACE - The present application relates to a dispense interface comprising at least a first flat part tightly connected with a second flat part, wherein at least one of the at least two flat parts comprises at least one deepening configured for forming at least one part of a channel profile, wherein the at least one deepening is formed by embossing, wherein the channel profile comprises at least a first inlet channel and a second inlet channel and at least one outlet channel, wherein each of the at least two inlet channels is configured for fluid communication with a respective reservoir of at least two reservoirs. | 04-23-2015 |
20160074586 | AN INJECTION DEVICE - Disclosed herein is a ready-to-use injection device for single use and a container for such device. The container comprises at least one first closed chamber for containine an active substance and optionally a second closed chamber for containing a quid substance comprising an active substance or a solvent. The two chambers are separated by a separation wall which is impermeable and breakable upon exertion of an external force, resulting in enhanced mixing of the substances contained in the device with a minimal formation of air bubbles. The present injection device is safe and particularly well suited for enhanced mixing of pharmaceutically active compositions to be injected in patients and can be used for vaccination programs. | 03-17-2016 |
20160106584 | APPARATUS AND METHODS FOR DRUG DELIVERY USING MULTIPLE RESERVOIRS - A cartridge, including a first member that defines an inner volume and a second member disposed therein, is disposed in a housing. A first reservoir is disposed in the inner volume in a position distal to the second member. The first member is partially disposed in a second reservoir, defined by the housing. The second member is configured to be moved from a first position, in which the first reservoir contains a drug and the second reservoir is fluidically isolated from the inner volume, toward a second position, in which the first reservoir and the second reservoir are in fluid communication with the inner volume, such that the second reservoir receives a volume of the drug from the first reservoir. The first member and the second member are collectively moved relative to the second reservoir to expel the volume of the drug from the second reservoir. | 04-21-2016 |
20160106909 | Apparatus for Simultaneous Multiple Medicament Administration - The invention relates to an apparatus and a method for simultaneous multiple medicine administration. The apparatus according to the invention comprises a housing in which at least two entry chambers and a collecting point are formed, wherein each entry chamber communicates with the collecting point via a flow path respectively and wherein in each flow path at least one penetration member is arranged, which causes a decrease in pressure downstream to the penetration member with respect to the pressure upstream to the penetration member. According to the method of the invention the independency of flow rates is eliminated irrespective of the equipment that is used, wherein a fluid is fed to a collecting point via separate flow paths and at least one penetration member is arranged within each flow path causing a decrease in pressure downstream to the penetration member with respect to the pressure upstream to the penetration member. | 04-21-2016 |
604088000 | Septum | 9 |
20080319385 | Fluid dispenser with additive sub-system - A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as, antibiotics, analgesics, and like medicinal agents from the device reservoir which is provided in the form of a novel bellows-type assembly. The fluid dispenser includes a unique stored energy mechanism which takes the form of a constant force spring member of novel design that provides the force necessary to continuously and substantially uniformly expel fluid from the device reservoir. The device also includes novel adjustable flow rate control assembly that is disposed intermediate the fluid reservoir outlet and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient. | 12-25-2008 |
20090118669 | Automatic Reconstitution Injector Device - The present invention is directed to an automatic reconstitution drug delivery device. The inventive device effects simple and automatic reconstitution of a dry drug. To effect reconstitution, a user displaces a release button which causes first and second chambers of a drug cartridge to communicate, resulting in automatic mixing of a diluent and dry drug to effect reconstitution of the dry drug. The user then simply sets the dose volume using a dose-setting mechanism, and administers the injection in a manner typical of self-injection drug delivery devices. Whole or partial automatic priming can be also achieved by the device. | 05-07-2009 |
20090326448 | Sterile Drug-Mixing Syringe - The invention is directed to a menstruum prepositioned type sterile drug-mixing syringe and a menstruum separately positioned type sterile drug-mixing syringe including a shell, a needle, a piston and a push-pull rod assembly. The syringe further includes a menstruum bottle, a solute bottle, a sliding sleeve and a needle loading assembly. The menstruum bottle may be fixed to the inner wall of a sliding sheath, and the solute bottle may be fixed to the inner of the shell. Piston may be disposed within the solute bottle. The sliding sleeve may be socketed to the front end of the shell in advance or disposed by other ways. The mouth of the menstruum bottle may be opposite to the mouth of the solute bottle and may be connected by a needle, which has two piercing tips, wherein the needle punctures and is securely connected to the needle loading assembly. | 12-31-2009 |
20110172595 | IMPLANTABLE SITE WITH SEPTUM PRESTRESSED IN TWO DIRECTIONS - The invention relates to an implantable medical device ( | 07-14-2011 |
20110264037 | VIAL ACCESS AND INJECTION SYSTEM - A device for mixing and transferring is described. The device comprises a housing having open ends, a container accessing member having at least one fluid conduit therethrough, the container accessing member extending generally outwardly from one end of the housing. The device comprises a fluid delivery device accessing member having at least one fluid conduit therethrough, the fluid delivery device accessing member extending generally outwardly from the other end of the housing having the container accessing member, the fluid delivery device accessing member and the container accessing member in fluid communication therewith. | 10-27-2011 |
20140243741 | ADMINISTRATION DEVICE FOR MIXING AN ACTIVE SUBSTANCE WITH A DILUTION LIQUID - An administration device comprises a container and a mixing device for mixing an active substance (in a first chamber) with a dilution liquid (in a second chamber). The container has a membrane seal at one end and is combined with a mixing device for mixing the active substance. The administration device has an injection needle unit with a distal needle portion facing away from the container for piercing the skin, and disposed opposite thereto is a proximal needle portion facing the membrane when the administration device is in the initial position, which is thrust through the membrane into the container in a mixing position. The administration device includes a protective sleeve arranged coaxially about the injection needle, movable from the initial position only in the proximal direction relative to the container. The protective sleeve can be non-rotatably connected to the container in the mixing position and rotated relative to the mixing device to perform mixing. | 08-28-2014 |
20150100018 | PRE-USE MIXING PRE-FILLED SYRINGE - A prefilled syringe of a before-use mixing type is provided, which does not require a bypass portion defined by a recessed inner surface portion of an outer cylinder. In the prefilled syringe, a first gasket ( | 04-09-2015 |
20150314071 | Valve Permitting Mixing in a Drug Delivery Device | 11-05-2015 |
20150374917 | Portable Drug Mixing and Delivery Device and Associated Methods - A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a valve between a first and second chamber that are slidably movable relative to each other and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete. | 12-31-2015 |